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ONTOLOGY REPORT - ANNOTATIONS

Term:transforming growth factor beta receptor activity
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Accession:GO:0005024 term browser browse the term
Definition:Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
Comment:Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand TGFbeta. For binding to other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.
Synonyms:exact_synonym: TGF-beta receptor activity;   TGFbeta receptor activity;   TGFbeta-activated receptor activity;   TGFbetaR;   transforming growth factor beta-activated receptor activity


show annotations for term's descendants           Sort by:
transforming growth factor beta receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor like type 1 enables ISO (PMID:8242742) RGD PMID:8242742 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591 		JBrowse link
G Amhr2 anti-Mullerian hormone receptor type 2 enables IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:133,579,152...133,588,874
Ensembl chr 7:133,579,393...133,588,258 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Eng endoglin enables NAS
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:15539634 GO_REF:0000033, RGD:1601032 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 contributes_to
enables		 ISO (PMID:1333888)
MGI:98729 (MGI:5688819|PMID:25065622), (PMID:15820682), (PMID:17878231)
(PMID:12015308), (PMID:12065756), (PMID:14633705), (PMID:18625725)		 RGD PMID:1333888 PMID:12015308 PMID:12065756 PMID:14633705 PMID:15820682 More... MGI:5688819 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 enables ISO
IBA		 (PMID:8635485)
MGI:98728 (PMID:17878231)
GO_REF:0000033
(PMID:12015308), (PMID:1333888), (PMID:18453574), (PMID:7852346)		 RGD
GO_Central		 PMID:1333888 PMID:7852346 PMID:8635485 PMID:12015308 PMID:17878231 More... GO_REF:0000033 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 enables TAS
ISO
IBA		 (MGI:3699491|PMID:17295310), (PMID:17823118), (PMID:9659379)
GO_REF:0000033
(PMID:12958365)		 RGD
GO_Central		 PMID:9659379 PMID:12958365 PMID:17295310 PMID:17823118 PMID:1657407 GO_REF:0000033 MGI:3699491, RGD:729942 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341 		JBrowse link
G Tgfbr3l transforming growth factor beta receptor 3 like enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:2,600,874...2,604,211
Ensembl chr12:2,600,934...2,604,222 		JBrowse link
transforming growth factor beta receptor activity, type I term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 enables IBA
ISO		 GO_REF:0000033
(PMID:8388127)		 GO_Central
RGD		 PMID:8388127 GO_REF:0000033 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241 		JBrowse link
G Acvrl1 activin A receptor like type 1 enables ISO
IBA		 (PMID:8242742)
GO_REF:0000033		 RGD
GO_Central		 PMID:8242742 GO_REF:0000033 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A enables ISO
IBA		 (PMID:9136927)
GO_REF:0000033		 RGD
GO_Central		 PMID:9136927 GO_REF:0000033 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B enables IBA
ISO		 GO_REF:0000033
(PMID:11376112)		 GO_Central
RGD		 PMID:11376112 GO_REF:0000033 NCBI chr 2:230,538,252...230,871,077
Ensembl chr 2:230,541,558...230,871,368 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 enables IMP
ISS
ISO
IEA
IBA		 GO_REF:0000024
(PMID:8752209)
GO_REF:0000107
GO_REF:0000033		 AgBase
RGD
Ensembl
GO_Central		 PMID:8752209 PMID:8272871 PMID:17505012 PMID:18684975 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:737663, RGD:2302021, RGD:2302517 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
transforming growth factor beta receptor activity, type II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amhr2 anti-Mullerian hormone receptor type 2 enables IDA
ISO		 PMID:11376112
(PMID:10854429)		 RGD PMID:10854429 PMID:11376112 RGD:8554753 NCBI chr 7:133,579,152...133,588,874
Ensembl chr 7:133,579,393...133,588,258 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 enables TAS
IEA
IMP		 GO_REF:0000104 UniProt
RGD		 PMID:12183510 PMID:18684975 GO_REF:0000104, RGD:727411, RGD:2302517 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
transforming growth factor beta receptor activity, type III term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfbr3 transforming growth factor beta receptor 3 enables ISO
IDA		 (PMID:10746731), (PMID:11157754)
PMID:8106553		 RGD PMID:10746731 PMID:11157754 PMID:8106553 RGD:1579949 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20890
    catalytic activity 6118
      catalytic activity, acting on a protein 2496
        protein kinase activity 621
          transmembrane receptor protein kinase activity 81
            transmembrane receptor protein serine/threonine kinase activity 21
              transforming growth factor beta receptor activity 11
                transforming growth factor beta receptor activity, type I 5
                transforming growth factor beta receptor activity, type II 2
                transforming growth factor beta receptor activity, type III 1
Path 2
Term Annotations click to browse term
  molecular_function 20890
    catalytic activity 6118
      transferase activity 2428
        transferase activity, transferring phosphorus-containing groups 970
          kinase activity 802
            protein kinase activity 621
              protein serine/threonine kinase activity 459
                transmembrane receptor protein serine/threonine kinase activity 21
                  transforming growth factor beta receptor activity 11
                    transforming growth factor beta receptor activity, type I 5
                    transforming growth factor beta receptor activity, type II 2
                    transforming growth factor beta receptor activity, type III 1
paths to the root