Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:cAMP-dependent protein kinase activity
go back to main search page
Accession:GO:0004691 term browser browse the term
Definition:cAMP-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.
Comment:This reaction requires the presence of cAMP.
Synonyms:exact_synonym: 3',5' cAMP-dependent protein kinase activity;   adenosine 3',5'-cyclophosphate-dependent protein kinase activity;   cAMP-dependent protein kinase, intrinsic catalyst activity;   cyclic AMP-dependent protein kinase activity
 broad_synonym: protein kinase A activity
 related_synonym: AMPK;   ATP:protein phosphotransferase (cAMP-dependent) activity;   PKA;   PKA C;   STK22
 alt_id: GO:0008602
 xref: EC:2.7.11.11;   Reactome:R-HSA-163672 "Phosphorylation of ChREBP at Thr(653) by PKA";   Reactome:R-HSA-163676 "Phosphorylation of pChREBP (Thr 653) at Ser(196) by PKA";   Reactome:R-HSA-9838321 "PRKACA phosphorylates TFAM in the mitochondrial matrix";   reactome:R-HSA-163773 "Phosphorylation of PF2K-Pase by PKA catalytic subunit";   reactome:R-HSA-177275 "PKA phosphorylates DARPP-32 on Thr34";   reactome:R-HSA-177284 "PKA phosphorylates PDE4B";   reactome:R-HSA-432232 "Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA)";   reactome:R-HSA-5610717 "PKA phosphorylates GLI2";   reactome:R-HSA-5610720 "PKA phosphorylates GLI3";   reactome:R-HSA-5610741 "PKA phosphorylates GLI1";   reactome:R-HSA-5617179 "PRKACA phosphorylates TNNI3";   reactome:R-HSA-5617182 "PRKACA phosphorylates PLN";   reactome:R-HSA-5687088 "PKA phosphorylates MAPKAPK5";   reactome:R-HSA-913451 "IL3RB is phosphorylated on Ser-585"


show annotations for term's descendants           Sort by:
cAMP-dependent protein kinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkaca protein kinase cAMP-activated catalytic subunit alpha enables IDA
IEA
IMP
ISO
TAS
IBA		 GO_REF:0000003
PMID:17190793
(PMID:22674394)
Reactome:R-RNO-164341
(PMID:21812984)
(PMID:11029056), (PMID:31112131)
GO_REF:0000117
GO_REF:0000033
MGI:3610390 (PMID:12200423), (PMID:16155866), (PMID:23292513), (PMID:23349500), (PMID:25475437)		 UniProt
RGD
Reactome
GO_Central		 PMID:11029056 PMID:12200423 PMID:16155866 PMID:21812984 PMID:22674394 More... GO_REF:0000003 GO_REF:0000033 GO_REF:0000117 Reactome:R-RNO-164341, RGD:1580675, RGD:2312556, RGD:2312572, RGD:10047304 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta enables IDA
ISS
ISO
IEA
IBA		 GO_REF:0000024
(MGI:1099550|PMID:9368018)
GO_REF:0000107
(PMID:12420224), (PMID:31112131)
GO_REF:0000033		 UniProt
RGD
Ensembl
GO_Central		 PMID:9368018 PMID:12420224 PMID:31112131 PMID:16816331 PMID:11907174 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:1099550, RGD:2312556, RGD:2312572 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198 		JBrowse link
G Prkx protein kinase cAMP-dependent X-linked catalytic subunit enables ISO (PMID:10026146), (PMID:17980165) RGD PMID:10026146 PMID:17980165 NCBI chr  X:41,823,349...41,866,844
Ensembl chr  X:41,823,355...41,866,669 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20890
    catalytic activity 6118
      catalytic activity, acting on a protein 2496
        protein kinase activity 621
          protein serine/threonine kinase activity 459
            cyclic nucleotide-dependent protein kinase activity 5
              cAMP-dependent protein kinase activity 3
Path 2
Term Annotations click to browse term
  molecular_function 20890
    catalytic activity 6118
      transferase activity 2428
        transferase activity, transferring phosphorus-containing groups 970
          kinase activity 802
            protein kinase activity 621
              protein serine/threonine kinase activity 459
                cyclic nucleotide-dependent protein kinase activity 5
                  cAMP-dependent protein kinase activity 3
paths to the root