ONTOLOGY REPORT - ANNOTATIONS

Term:pancreatic A cell differentiation
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Accession:GO:0003310 term browser browse the term
Definition:The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon.
Synonyms:exact_synonym: pancreatic alpha cell differentiation

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pancreatic A cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Gata6 GATA binding protein 6 GBrowse link ISO 18 2,504,264 2,534,648 RGD:1624291 RGD
G Rfx6 regulatory factor X, 6 GBrowse link ISO 20 30,344,712 30,391,212 RGD:1624291 RGD
negative regulation of pancreatic A cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Hes1 hairy and enhancer of split 1 (Drosophila) GBrowse link ISO 11 72,603,482 72,605,673 RGD:1624291 RGD
pancreatic A cell development term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Pax6 paired box 6 GBrowse link ISO 3 91,127,605 91,149,178 RGD:1624291 RGD
G Pax6 paired box 6 GBrowse link ISO 3 91,127,605 91,149,178 RGD:1624291 RGD
G Pax6 paired box 6 GBrowse link IMP 3 91,127,605 91,149,178 BHF-UCL
pancreatic A cell fate commitment term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Neurod1 neuronal differentiation 1 GBrowse link ISO 3 62,224,633 62,227,936 RGD:1624291 RGD
G Neurod1 neuronal differentiation 1 GBrowse link IEA 3 62,224,633 62,227,936 RGD:1600115 ENSEMBL
G Nkx2-2 NK2 homeobox 2 GBrowse link ISO 3 135,837,591 135,839,963 RGD:1624291 RGD
G Nkx2-2 NK2 homeobox 2 GBrowse link ISO 3 135,837,591 135,839,963 RGD:1624291 RGD
G Nkx2-2 NK2 homeobox 2 GBrowse link IEA 3 135,837,591 135,839,963 RGD:1600115 ENSEMBL
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 135967
    developmental process 29431
      single-organism developmental process 22738
        endocrine pancreas development 87
          pancreatic A cell differentiation 11
            negative regulation of pancreatic A cell differentiation 1
            pancreatic A cell development 3
            pancreatic A cell fate commitment 5
            positive regulation of pancreatic A cell differentiation 0
            regulation of pancreatic A cell differentiation + 1
Path 2
Term Annotations click to browse term
  biological_process 135967
    developmental process 29431
      anatomical structure development 26183
        tissue development 5885
          epithelium development 2807
            epithelial cell differentiation 1196
              columnar/cuboidal epithelial cell differentiation 176
                glandular epithelial cell differentiation 70
                  enteroendocrine cell differentiation 49
                    pancreatic A cell differentiation 11
                      negative regulation of pancreatic A cell differentiation 1
                      pancreatic A cell development 3
                      pancreatic A cell fate commitment 5
                      positive regulation of pancreatic A cell differentiation 0
                      regulation of pancreatic A cell differentiation + 1
paths to the root

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