ONTOLOGY REPORT - ANNOTATIONS

Term:endocardial cushion to mesenchymal transition involved in heart valve formation
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Accession:GO:0003199 term browser browse the term
Definition:A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of a cardiac valve.
Synonyms:exact_synonym: endocardial cushion to mesenchymal transition involved in valve formation

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endocardial cushion to mesenchymal transition involved in heart valve formation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Efna1 ephrin A1 GBrowse link ISO 2 181,444,599 181,451,944 RGD:1624291 RGD
G Efna1 ephrin A1 GBrowse link IEA 2 181,444,599 181,451,944 RGD:1600115 ENSEMBL
G Hey1 hairy/enhancer-of-split related with YRPW motif 1 GBrowse link ISO 2 95,174,030 95,176,430 RGD:1624291 RGD
G Hey1 hairy/enhancer-of-split related with YRPW motif 1 GBrowse link IEA 2 95,174,030 95,176,430 RGD:1600115 ENSEMBL
G Hey2 hairy/enhancer-of-split related with YRPW motif 2 GBrowse link ISO 1 27,505,117 27,515,204 RGD:1624291 RGD
G Hey2 hairy/enhancer-of-split related with YRPW motif 2 GBrowse link IEA 1 27,505,117 27,515,204 RGD:1600115 ENSEMBL
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Twist1 twist basic helix-loop-helix transcription factor 1 GBrowse link ISO 6 52,605,869 52,607,863 RGD:1624291 RGD
G Twist1 twist basic helix-loop-helix transcription factor 1 GBrowse link IEA 6 52,605,869 52,607,863 RGD:1600115 ENSEMBL
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 136531
    single-organism process 88879
      single-organism developmental process 22842
        heart valve formation 25
          endocardial cushion to mesenchymal transition involved in heart valve formation 8
            negative regulation of endocardial cushion to mesenchymal transition involved in heart valve formation 0
            positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation 2
            regulation of endocardial cushion to mesenchymal transition involved in heart valve formation + 2
Path 2
Term Annotations click to browse term
  biological_process 136531
    single-organism process 88879
      single-multicellular organism process 36188
        multicellular organismal development 24679
          system development 21210
            organ development 14177
              mesenchyme development 450
                mesenchymal cell differentiation 349
                  mesenchymal cell development 306
                    epithelial to mesenchymal transition 194
                      cardiac epithelial to mesenchymal transition 44
                        endocardial cushion to mesenchymal transition 8
                          endocardial cushion to mesenchymal transition involved in heart valve formation 8
                            negative regulation of endocardial cushion to mesenchymal transition involved in heart valve formation 0
                            positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation 2
                            regulation of endocardial cushion to mesenchymal transition involved in heart valve formation + 2
paths to the root

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