epithelial to mesenchymal transition involved in endocardial cushion formation - Ontology Report

Keyword

ONTOLOGY REPORT - ANNOTATIONS

Term:	epithelial to mesenchymal transition involved in endocardial cushion formation	go back to main search page
Accession:	GO:0003198	browse the term
Definition:	A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the endocardial cushion.

epithelial to mesenchymal transition involved in endocardial cushion formation
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Fgf8	fibroblast growth factor 8		ISO	1	250,951,023	250,956,730	RGD:1624291	RGD
G	Fgf8	fibroblast growth factor 8		ISO	1	250,951,023	250,956,730	RGD:1624291	RGD
G	Fgf8	fibroblast growth factor 8		IEA	1	250,951,023	250,956,730	RGD:1600115	ENSEMBL
G	Hey1	hairy/enhancer-of-split related with YRPW motif 1		ISO	2	95,174,030	95,176,430	RGD:1624291	RGD
G	Hey1	hairy/enhancer-of-split related with YRPW motif 1		ISS	2	95,174,030	95,176,430	RGD:1600115	UniProtKB
G	Heyl	hairy/enhancer-of-split related with YRPW motif-like		ISO	5	142,544,185	142,561,176	RGD:1624291	RGD
G	Msx1	msh homeobox 1		ISO	14	78,257,345	78,261,144	RGD:1624291	RGD
G	Msx1	msh homeobox 1		IEA	14	78,257,345	78,261,144	RGD:1600115	ENSEMBL
G	Msx2	msh homeobox 2		ISO	17	17,243,262	17,248,927	RGD:1624291	RGD
G	Msx2	msh homeobox 2		IEA	17	17,243,262	17,248,927	RGD:1600115	ENSEMBL
G	Notch1	notch 1		IEA	3	4,631,797	4,677,640	RGD:1600115	ENSEMBL
G	Notch1	notch 1		ISO	3	4,631,797	4,677,640	RGD:1624291	RGD
G	Rbpj	recombination signal binding protein for immunoglobulin kappa J region		ISO				RGD:1624291	RGD
G	Snai1	snail homolog 1 (Drosophila)		ISO	3	158,676,980	158,681,471	RGD:1624291	RGD
G	Snai2	snail homolog 2 (Drosophila)		ISO				RGD:1624291	RGD
G	Snai2	snail homolog 2 (Drosophila)		IEA				RGD:1600115	ENSEMBL

Term paths to the root

Path 1
Term	Annotations
biological_process	135967
developmental process	29431
single-organism developmental process	22738
endocardial cushion formation	24
epithelial to mesenchymal transition involved in endocardial cushion formation	16
Path 2
Term	Annotations
biological_process	135967
multicellular organismal process	37265
single-multicellular organism process	36068
multicellular organismal development	24588
system development	21128
circulatory system development	3309
cardiovascular system development	3308
heart development	1844
heart morphogenesis	757
endocardial cushion morphogenesis	39
endocardial cushion formation	24
epithelial to mesenchymal transition involved in endocardial cushion formation	16