B cell affinity maturation - Ontology Report

Keyword

ONTOLOGY REPORT - ANNOTATIONS

Term:	B cell affinity maturation	go back to main search page
Accession:	GO:0002344	browse the term
Definition:	The process in which B cells produce antibodies with increased antigen affinity. This is accomplished by somatic hypermutation and selection for B cells which produce higher affinity antibodies to antigen.
Comment:	This term was added by GO_REF:0000022.
Synonyms:	exact_synonym:	B-lymphocyte affinity maturation

B cell affinity maturation
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	LOC688090	similar to RT1 class II histocompatibility antigen, B-1 beta chain precursor (RT1.B-beta(1))		IEA				RGD:1600115	ENSEMBL
G	RT1-Bb	RT1 class II, locus Bb		ISO	20	4,730,559	4,736,201	RGD:1624291	RGD

Term paths to the root

Path 1
Term	Annotations
biological_process	136531
immune system process	6166
B cell selection	6
peripheral B cell selection	2
B cell affinity maturation	2
somatic hypermutation of immunoglobulin genes involved in immune response	0
Path 2
Term	Annotations
biological_process	136531
single-organism process	88879
single-multicellular organism process	36188
multicellular organismal development	24679
system development	21210
organ development	14177
hematopoietic or lymphoid organ development	1965
hemopoiesis	1788
leukocyte differentiation	1130
lymphocyte differentiation	753
B cell differentiation	160
B cell selection	6
peripheral B cell selection	2
B cell affinity maturation	2
somatic hypermutation of immunoglobulin genes involved in immune response	0