ONTOLOGY REPORT - ANNOTATIONS

Term:natural killer cell mediated immunity
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Accession:GO:0002228 term browser browse the term
Definition:The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines.
Comment:This term was added by GO_REF:0000022.
Synonyms:exact_synonym: NK cell mediated immunity

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natural killer cell degranulation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Rab27a RAB27A, member RAS oncogene family GBrowse link ISO 8 77,798,830 77,861,090 RGD:1624291 RGD
G Rab27a RAB27A, member RAS oncogene family GBrowse link IEA 8 77,798,830 77,861,090 RGD:1600115 ENSEMBL
G Unc13d unc-13 homolog D (C. elegans) GBrowse link ISO 10 106,170,475 106,185,215 RGD:1624291 RGD
G Unc13d unc-13 homolog D (C. elegans) GBrowse link IEA 10 106,170,475 106,185,215 RGD:1600115 ENSEMBL
natural killer cell mediated cytotoxicity term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cebpg CCAAT/enhancer binding protein (C/EBP), gamma GBrowse link ISO 1 87,552,695 87,559,447 RGD:1624291 RGD
G Cebpg CCAAT/enhancer binding protein (C/EBP), gamma GBrowse link ISS 1 87,552,695 87,559,447 RGD:1600115 UniProtKB
G Lyst lysosomal trafficking regulator GBrowse link ISO 17 66,569,478 66,735,402 RGD:1624291 RGD
G Lyst lysosomal trafficking regulator GBrowse link ISO 17 66,569,478 66,735,402 RGD:1624291 RGD
G Prdx1 peroxiredoxin 1 GBrowse link ISO 5 136,975,780 136,991,630 RGD:1624291 RGD
G Prdx1 peroxiredoxin 1 GBrowse link IEA 5 136,975,780 136,991,630 RGD:1600115 ENSEMBL
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 GBrowse link ISO 4 160,843,699 160,868,856 RGD:1624291 RGD
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 GBrowse link IEA 4 160,843,699 160,868,856 RGD:1600115 ENSEMBL
negative regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Arrb2 arrestin, beta 2 GBrowse link ISO 10 57,244,071 57,284,166 RGD:1624291 RGD
G Arrb2 arrestin, beta 2 GBrowse link IEA 10 57,244,071 57,284,166 RGD:1600115 ENSEMBL
G LOC687009 similar to EAT-2-related transducer IEA RGD:1600115 ENSEMBL
G RT1-A1 RT1 class Ia, locus A1 GBrowse link IMP 20 5,056,763 5,060,280 RGD:2313500 RGD
G Sh2d1b SH2 domain containing 1B GBrowse link ISO 13 86,096,465 86,126,881 RGD:1624291 RGD
G Sh2d1b SH2 domain containing 1B GBrowse link IEA 13 86,096,465 86,126,881 RGD:1600115 ENSEMBL
G Sh2d1b2 SH2 domain protein 1B2 GBrowse link ISO 13 86,047,216 86,067,302 RGD:1624291 RGD
G Sh2d1b2 SH2 domain protein 1B2 GBrowse link IEA 13 86,047,216 86,067,302 RGD:1600115 ENSEMBL
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Klre1 killer cell lectin-like receptor, family E, member 1 GBrowse link IDA 4 166,857,685 166,864,221 RGD:1299590 RGD
positive regulation of natural killer cell cytokine production term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Gimap5 GTPase, IMAP family member 5 GBrowse link IMP 4 76,836,521 76,843,214 RGD:2303778 RGD
G Il21 interleukin 21 GBrowse link ISO 2 123,774,331 123,781,697 RGD:1624291 RGD
G Il21 interleukin 21 GBrowse link IEA 2 123,774,331 123,781,697 RGD:1600115 ENSEMBL
positive regulation of natural killer cell mediated cytotoxicity term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cadm1 cell adhesion molecule 1 GBrowse link ISO 8 50,765,645 51,108,962 RGD:1624291 RGD
G Cadm1 cell adhesion molecule 1 GBrowse link ISO 8 50,765,645 51,108,962 RGD:1624291 RGD
G Cadm1 cell adhesion molecule 1 GBrowse link ISS 8 50,765,645 51,108,962 RGD:1600115 UniProtKB
G Cd226 CD226 molecule GBrowse link ISO 18 86,064,574 86,157,909 RGD:1624291 RGD
G Crtam cytotoxic and regulatory T cell molecule GBrowse link ISO 8 43,943,971 43,981,609 RGD:1624291 RGD
G Crtam cytotoxic and regulatory T cell molecule GBrowse link ISO 8 43,943,971 43,981,609 RGD:1624291 RGD
G Gimap5 GTPase, IMAP family member 5 GBrowse link IMP 4 76,836,521 76,843,214 RGD:2303778 RGD
G Il12a interleukin 12A GBrowse link ISO 2 158,710,261 158,717,689 RGD:1624291 RGD
G Il21 interleukin 21 GBrowse link ISO 2 123,774,331 123,781,697 RGD:1624291 RGD
G Il21 interleukin 21 GBrowse link IEA 2 123,774,331 123,781,697 RGD:1600115 ENSEMBL
G Klre1 killer cell lectin-like receptor, family E, member 1 GBrowse link ISO 4 166,857,685 166,864,221 RGD:1624291 RGD
G Klre1 killer cell lectin-like receptor, family E, member 1 GBrowse link IEA 4 166,857,685 166,864,221 RGD:1600115 ENSEMBL
G Klrk1 killer cell lectin-like receptor subfamily K, member 1 GBrowse link ISO 4 166,914,786 166,922,659 RGD:1624291 RGD
G Klrk1 killer cell lectin-like receptor subfamily K, member 1 GBrowse link IEA 4 166,914,786 166,922,659 RGD:1600115 ENSEMBL
G Lag3 lymphocyte-activation gene 3 GBrowse link ISO 4 161,031,506 161,039,255 RGD:1624291 RGD
G Lag3 lymphocyte-activation gene 3 GBrowse link IEA 4 161,031,506 161,039,255 RGD:1600115 ENSEMBL
G Ly49s3 Ly-49 stimulatory receptor 3 GBrowse link IDA 4 168,023,598 168,209,373 RGD:633264 RGD
G Ncr3 natural cytotoxicity triggering receptor 3 GBrowse link IEA 20 3,701,807 3,707,278 RGD:1600115 ENSEMBL
G PVR poliovirus receptor GBrowse link ISO 1 79,213,654 79,229,063 RGD:1624291 RGD
G Pvrl2 poliovirus receptor-related 2 GBrowse link ISO 1 79,021,831 79,059,686 RGD:1624291 RGD
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 GBrowse link ISO 20 1,412,553 1,416,692 RGD:1624291 RGD
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 GBrowse link IEA 20 1,412,553 1,416,692 RGD:1600115 ENSEMBL
G Sh2d1a SH2 domain containing 1A GBrowse link ISO X 2,532,295 2,560,524 RGD:1624291 RGD
G Sh2d1a SH2 domain containing 1A GBrowse link IEA X 2,532,295 2,560,524 RGD:1600115 ENSEMBL
G Stat5a signal transducer and activator of transcription 5A GBrowse link ISO 10 89,795,404 89,819,732 RGD:1624291 RGD
G Stat5a signal transducer and activator of transcription 5A GBrowse link IEA 10 89,795,404 89,819,732 RGD:1600115 ENSEMBL
G Stat5b signal transducer and activator of transcription 5B GBrowse link ISO 10 89,716,624 89,743,134 RGD:1624291 RGD
G Stat5b signal transducer and activator of transcription 5B GBrowse link IEA 10 89,716,624 89,743,134 RGD:1600115 ENSEMBL
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cd226 CD226 molecule GBrowse link ISO 18 86,064,574 86,157,909 RGD:1624291 RGD
G Crtam cytotoxic and regulatory T cell molecule GBrowse link ISO 8 43,943,971 43,981,609 RGD:1624291 RGD
G Crtam cytotoxic and regulatory T cell molecule GBrowse link IEA 8 43,943,971 43,981,609 RGD:1600115 ENSEMBL
G Crtam cytotoxic and regulatory T cell molecule GBrowse link ISO 8 43,943,971 43,981,609 RGD:1624291 RGD
G Il12a interleukin 12A GBrowse link ISO 2 158,710,261 158,717,689 RGD:1624291 RGD
G Il12a interleukin 12A GBrowse link IEA 2 158,710,261 158,717,689 RGD:1600115 ENSEMBL
G Il12b interleukin 12B GBrowse link ISO 10 29,558,955 29,568,331 RGD:1624291 RGD
G PVR poliovirus receptor GBrowse link ISO 1 79,213,654 79,229,063 RGD:1624291 RGD
G Pvrl2 poliovirus receptor-related 2 GBrowse link ISO 1 79,021,831 79,059,686 RGD:1624291 RGD
G Pvrl2 poliovirus receptor-related 2 GBrowse link IEA 1 79,021,831 79,059,686 RGD:1600115 ENSEMBL
positive regulation of natural killer cell mediated immunity term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Sh2d1b SH2 domain containing 1B GBrowse link ISO 13 86,096,465 86,126,881 RGD:1624291 RGD
protection from natural killer cell mediated cytotoxicity term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Clec2d C-type lectin domain family 2, member D GBrowse link ISO 4 165,998,313 166,008,311 RGD:1624291 RGD
G Clec2d C-type lectin domain family 2, member D GBrowse link ISO 4 165,998,313 166,008,311 RGD:1624291 RGD
G Clec2d C-type lectin domain family 2, member D GBrowse link ISO 4 165,998,313 166,008,311 RGD:1624291 RGD
G Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) GBrowse link IMP 20 4,790,363 4,800,730 RGD:2312378 RGD
G Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) GBrowse link IMP 20 4,770,446 4,784,488 RGD:2312378 RGD
susceptibility to natural killer cell mediated cytotoxicity term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cadm1 cell adhesion molecule 1 GBrowse link ISO 8 50,765,645 51,108,962 RGD:1624291 RGD
G Cadm1 cell adhesion molecule 1 GBrowse link ISO 8 50,765,645 51,108,962 RGD:1624291 RGD
G Cadm1 cell adhesion molecule 1 GBrowse link ISS 8 50,765,645 51,108,962 RGD:1600115 UniProtKB
G PVR poliovirus receptor GBrowse link ISO 1 79,213,654 79,229,063 RGD:1624291 RGD
G Pvrl2 poliovirus receptor-related 2 GBrowse link ISO 1 79,021,831 79,059,686 RGD:1624291 RGD
G Pvrl2 poliovirus receptor-related 2 GBrowse link IEA 1 79,021,831 79,059,686 RGD:1600115 ENSEMBL
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 135967
    immune system process 6124
      immune response 2069
        innate immune response 649
          natural killer cell mediated immunity 74
            natural killer cell cytokine production + 3
            natural killer cell mediated cytotoxicity + 70
            natural killer cell mediated immune response to tumor cell + 11
            negative regulation of natural killer cell mediated immunity + 14
            positive regulation of natural killer cell mediated immunity + 48
            regulation of natural killer cell mediated immunity + 62
Path 2
Term Annotations click to browse term
  biological_process 135967
    immune system process 6124
      immune effector process 1053
        leukocyte mediated immunity 479
          lymphocyte mediated immunity 379
            natural killer cell mediated immunity 74
              natural killer cell cytokine production + 3
              natural killer cell mediated cytotoxicity + 70
              natural killer cell mediated immune response to tumor cell + 11
              negative regulation of natural killer cell mediated immunity + 14
              positive regulation of natural killer cell mediated immunity + 48
              regulation of natural killer cell mediated immunity + 62
paths to the root

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