Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CLINICAL MEASUREMENT - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio
go back to main search page
Accession:CMO:0001990 term browser browse the term
Definition:A calculated measurement in which the number of lymphocytes expressing both a relatively high amount of surface CD45RC antigen and surface CD8 antigen is divided by the number of lymphocytes expressing both a relatively low amount of surface CD45RC antigen and surface CD8 antigen, and presented as a ratio, fraction, quotient or percentage. CD45RC, also known as the leukocyte common antigen, is the protein produced by the PTPRC (protein tyrosine phosphatase, receptor type, C) gene and has been shown to be an essential regulator of T- and B-cell antigen receptor signaling.
Synonyms:exact_synonym: blood CD45RChigh CD8 T cell count to CD45RClow CD8 T cell count ratio


show annotations for term's descendants           Sort by:
blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Cdexp1 CD45RC expression in CD8 T cells QTL 1 IDA RGD PMID:15322174 RGD:1302824 NCBI chr 9:1,024,537...67,509,080 JBrowse link
Q Cdexp2 CD45RC expression in CD8 T cells QTL 2 IDA RGD PMID:15322174 RGD:1302824 NCBI chr20:3,621,649...10,078,919 JBrowse link

Related Phenotype Data for Term "blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio" (CMO:0001990)

Rat Strains:
Clinical Measurements:
Experimental Conditions:
Measurement Methods:
Term paths to the root
Path 1
Term Annotations click to browse term
  clinical measurement 2369
    cell measurement 24
      mononuclear cell measurement 7
        mononuclear cell count 7
          blood mononuclear cell count 3
            blood lymphocyte count 3
              blood T lymphocyte count 3
                blood CD8 cell count 2
                  calculated blood CD8 cell count 2
                    blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio 2
Path 2
Term Annotations click to browse term
  clinical measurement 2369
    cell measurement 24
      immune cell measurement 16
        white blood cell measurement 15
          white blood cell count 15
            mononuclear cell count 7
              blood mononuclear cell count 3
                blood lymphocyte count 3
                  blood T lymphocyte count 3
                    blood CD8 cell count 2
                      calculated blood CD8 cell count 2
                        blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio 2
paths to the root