ONTOLOGY REPORT - ANNOTATIONS

Term:thimerosal
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Accession:CHEBI:9546 term browser browse the term
Definition:An organomercury compound (approximately 49% mercury by weight) used as an antiseptic and antifungal agent.
Synonyms:exact_synonym: sodium [(2-carboxylatophenyl)sulfanyl](ethyl)mercurate(1-);   sodium ethyl[2-(sulfanyl-kappaS)benzoato(2-)]mercurate(1-)
 related_synonym: C9H9HgNaO2S;   C9H9HgO2S.Na;   InChI=1S/C7H6O2S.C2H5.Hg.Na/c8-7(9)5-3-1-2-4-6(5)10;1-2;;/h1-4,10H,(H,8,9);1H2,2H3;;/q;;2*+1/p-2;   InChIKey=RTKIYNMVFMVABJ-UHFFFAOYSA-L;   Merthiolate;   Thiomersal;   [(o-carboxyphenyl)thio]ethylmercury sodium salt;   [Na+].CC[Hg]Sc1ccccc1C([O-])=O;   ethyl(2-mercaptobenzoato-S)mercury sodium salt;   ethylmercurithiosalicylate sodium;   mercurothiolate;   o-(ethylmercurithio)benzoic acid sodium salt;   thiomersalate
 xref_casrn: 54-64-8
 xref: Beilstein:8169555 "Beilstein Registry Number";   ChEMBL:545859 "ChEMBL COMPOUND";   ChemIDplus:54-64-8 "CAS Registry Number";   CiteXplore:18837732 "PubMed citation";   CiteXplore:21616561 "PubMed citation";   Gmelin:1677155 "Gmelin Registry Number";   KEGG COMPOUND:C08044 "KEGG COMPOUND"
 xref_mesh: MESH:D013849

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thimerosal term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 GBrowse link increases secretion ISO X 45,828,121 45,866,603 RGD:6480464 CTD
G Alb albumin GBrowse link affects binding ISO 5 90,889,915 90,905,629 RGD:6480464 CTD
G Arc activity regulated cytoskeletal-associated protein GBrowse link increases expression ISO 15 74,499,513 74,503,000 RGD:6480464 CTD
G Atf3 activating transcription factor 3 GBrowse link increases expression ISO 1 192,994,175 193,007,212 RGD:6480464 CTD
G Bag3 BCL2-associated athanogene 3 GBrowse link increases expression ISO 7 135,667,097 135,690,495 RGD:6480464 CTD
G Birc3 baculoviral IAP repeat-containing 3 GBrowse link multiple interactions ISO 9 7,848,699 7,873,170 RGD:6480464 CTD
G Birc3 baculoviral IAP repeat-containing 3 GBrowse link decreases expression ISO 9 7,848,699 7,873,170 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 8 47,702,803 47,724,071 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases cleavage ISO 8 47,702,803 47,724,071 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 8 47,702,803 47,724,071 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 8 47,702,803 47,724,071 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 8 47,702,803 47,724,071 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 8 47,702,803 47,724,071 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 8 47,702,803 47,724,071 RGD:6480464 CTD
G Casp9 caspase 9 GBrowse link increases cleavage ISO 4 141,349,527 141,371,890 RGD:6480464 CTD
G Casp9 caspase 9 GBrowse link multiple interactions ISO 4 141,349,527 141,371,890 RGD:6480464 CTD
G Casp9 caspase 9 GBrowse link increases activity ISO 4 141,349,527 141,371,890 RGD:6480464 CTD
G Ccnb1 cyclin B1 GBrowse link multiple interactions ISO 13 101,548,694 101,556,441 RGD:6480464 CTD
G Cd28 CD28 antigen GBrowse link affects response to substance EXP 1 60,803,232 60,830,203 RGD:6480464 CTD
G Cd86 CD86 antigen GBrowse link increases expression ISO 16 36,603,955 36,666,163 RGD:6480464 CTD
G Cd86 CD86 antigen GBrowse link multiple interactions ISO 16 36,603,955 36,666,163 RGD:6480464 CTD
G Cd86 CD86 antigen GBrowse link multiple interactions ISO 16 36,603,955 36,666,163 RGD:6480464 CTD
G Cd86 CD86 antigen GBrowse link increases expression ISO 16 36,603,955 36,666,163 RGD:6480464 CTD
G Cd86 CD86 antigen GBrowse link increases expression ISO 16 36,603,955 36,666,163 RGD:6480464 CTD
G Cd86 CD86 antigen GBrowse link increases expression ISO 16 36,603,955 36,666,163 RGD:6480464 CTD
G Cdk4 cyclin-dependent kinase 4 GBrowse link decreases expression ISO 10 126,500,659 126,504,339 RGD:6480464 CTD
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 GBrowse link increases expression ISO 10 17,443,034 17,445,480 RGD:6480464 CTD
G Clu clusterin GBrowse link increases expression ISO 14 66,587,320 66,600,382 RGD:6480464 CTD
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 GBrowse link increases expression ISO 19 37,095,781 37,281,783 RGD:6480464 CTD
G Cryab crystallin, alpha B GBrowse link increases expression ISO 9 50,560,863 50,564,738 RGD:6480464 CTD
G Cyr61 cysteine rich protein 61 GBrowse link increases expression ISO 3 145,309,935 145,312,949 RGD:6480464 CTD
G Dnajb1 DnaJ (Hsp40) homolog, subfamily B, member 1 GBrowse link increases expression ISO 8 86,132,074 86,135,802 RGD:6480464 CTD
G Dnajb4 DnaJ (Hsp40) homolog, subfamily B, member 4 GBrowse link increases expression ISO 3 151,846,919 151,873,263 RGD:6480464 CTD
G Dusp1 dual specificity phosphatase 1 GBrowse link increases expression ISO 17 26,642,536 26,645,417 RGD:6480464 CTD
G Fos FBJ osteosarcoma oncogene GBrowse link increases expression ISO 12 86,814,851 86,818,219 RGD:6480464 CTD
G Fosb FBJ osteosarcoma oncogene B GBrowse link increases expression ISO 7 19,888,045 19,895,394 RGD:6480464 CTD
G Gadd45g growth arrest and DNA-damage-inducible 45 gamma GBrowse link increases expression ISO 13 51,942,044 51,943,844 RGD:6480464 CTD
G Gemin4 gem (nuclear organelle) associated protein 4 GBrowse link decreases expression ISO 11 76,024,073 76,031,074 RGD:6480464 CTD
G Grik5 glutamate receptor, ionotropic, kainate 5 (gamma 2) GBrowse link affects expression EXP 7 25,794,868 25,857,388 RGD:6480464 CTD
G Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) GBrowse link decreases expression EXP 2 25,146,697 25,174,683 RGD:6480464 CTD
G Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) GBrowse link decreases expression EXP 6 135,679,813 136,123,529 RGD:6480464 CTD
G Gstm1 glutathione S-transferase, mu 1 GBrowse link affects response to substance ISO 3 107,815,168 107,820,891 RGD:6480464 CTD
G Gstt1 glutathione S-transferase, theta 1 GBrowse link affects response to substance ISO 10 75,246,558 75,261,329 RGD:6480464 CTD
G Hbegf heparin-binding EGF-like growth factor GBrowse link increases expression ISO 18 36,664,581 36,675,459 RGD:6480464 CTD
G Hist1h3b histone cluster 1, H3b GBrowse link increases expression ISO 13 23,844,249 23,844,659 RGD:6480464 CTD
G Hist1h3g histone cluster 1, H3g GBrowse link increases expression ISO 13 23,627,287 23,627,778 RGD:6480464 CTD
G Hmox1 heme oxygenase (decycling) 1 GBrowse link increases expression ISO 8 77,617,517 77,624,492 RGD:6480464 CTD
G Hspa1a heat shock protein 1A GBrowse link increases expression ISO 17 35,106,304 35,109,101 RGD:6480464 CTD
G Hspa1b heat shock protein 1B GBrowse link increases expression ISO 17 35,093,374 35,096,183 RGD:6480464 CTD
G Hspa1l heat shock protein 1-like GBrowse link increases expression ISO 17 35,109,648 35,116,173 RGD:6480464 CTD
G Hspb1 heat shock protein 1 GBrowse link increases expression ISO 5 136,363,789 136,365,433 RGD:6480464 CTD
G Ifng interferon gamma GBrowse link affects response to substance EXP 10 117,878,103 117,882,948 RGD:6480464 CTD
G Ifng interferon gamma GBrowse link multiple interactions ISO 10 117,878,103 117,882,948 RGD:6480464 CTD
G Igf1 insulin-like growth factor 1 GBrowse link multiple interactions ISO 10 87,321,801 87,399,792 RGD:6480464 CTD
G Il13 interleukin 13 GBrowse link multiple interactions ISO 11 53,444,825 53,448,204 RGD:6480464 CTD
G Il5 interleukin 5 GBrowse link multiple interactions ISO 11 53,534,296 53,538,605 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link affects response to substance EXP 5 30,339,701 30,346,508 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link multiple interactions ISO 5 30,339,701 30,346,508 RGD:6480464 CTD
G Il8 interleukin 8 GBrowse link multiple interactions ISO 5 91,223,560 91,232,093 RGD:6480464 CTD
G Il8 interleukin 8 GBrowse link increases secretion ISO 5 91,223,560 91,232,093 RGD:6480464 CTD
G Il8 interleukin 8 GBrowse link increases secretion ISO 5 91,223,560 91,232,093 RGD:6480464 CTD
G Il8 interleukin 8 GBrowse link increases secretion ISO 5 91,223,560 91,232,093 RGD:6480464 CTD
G Jun Jun oncogene GBrowse link increases expression ISO 4 94,715,727 94,718,913 RGD:6480464 CTD
G Kansl1l KAT8 regulatory NSL complex subunit 1-like GBrowse link increases expression ISO 1 66,765,817 66,864,169 RGD:6480464 CTD
G Klf4 Kruppel-like factor 4 (gut) GBrowse link increases expression ISO 4 55,540,009 55,545,347 RGD:6480464 CTD
G Mafb v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) GBrowse link increases expression ISO 2 160,189,413 160,192,801 RGD:6480464 CTD
G Mapk1 mitogen-activated protein kinase 1 GBrowse link multiple interactions ISO 16 16,983,475 17,047,546 RGD:6480464 CTD
G Mapk1 mitogen-activated protein kinase 1 GBrowse link decreases phosphorylation ISO 16 16,983,475 17,047,546 RGD:6480464 CTD
G Mapk14 mitogen-activated protein kinase 14 GBrowse link increases phosphorylation ISO 17 28,828,287 28,885,350 RGD:6480464 CTD
G Mapk3 mitogen-activated protein kinase 3 GBrowse link decreases phosphorylation ISO 7 133,903,140 133,909,330 RGD:6480464 CTD
G Mapk3 mitogen-activated protein kinase 3 GBrowse link multiple interactions ISO 7 133,903,140 133,909,330 RGD:6480464 CTD
G Mapk3 mitogen-activated protein kinase 3 GBrowse link increases phosphorylation ISO 7 133,903,140 133,909,330 RGD:6480464 CTD
G Mapk8 mitogen-activated protein kinase 8 GBrowse link increases phosphorylation ISO 14 34,191,084 34,260,344 RGD:6480464 CTD
G Mapk9 mitogen-activated protein kinase 9 GBrowse link increases phosphorylation ISO 11 49,660,253 49,699,923 RGD:6480464 CTD
G Med18 mediator of RNA polymerase II transcription, subunit 18 homolog (yeast) GBrowse link decreases expression ISO 4 132,014,644 132,019,836 RGD:6480464 CTD
G Mt1 metallothionein 1 GBrowse link increases expression EXP 8 96,702,989 96,704,227 RGD:6480464 CTD
G Mt1 metallothionein 1 GBrowse link affects expression EXP 8 96,702,989 96,704,227 RGD:6480464 CTD
G Mt2 metallothionein 2 GBrowse link increases expression EXP 8 96,696,518 96,697,467 RGD:6480464 CTD
G Mt3 metallothionein 3 GBrowse link increases expression EXP 8 96,676,507 96,678,048 RGD:6480464 CTD
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase GBrowse link multiple interactions ISO 13 12,279,086 12,350,267 RGD:6480464 CTD
G Mxd1 MAX dimerization protein 1 GBrowse link increases expression ISO 6 86,597,038 86,619,153 RGD:6480464 CTD
G Ngf nerve growth factor GBrowse link multiple interactions ISO 3 102,273,851 102,324,936 RGD:6480464 CTD
G Ngf nerve growth factor GBrowse link decreases response to substance ISO 3 102,273,851 102,324,936 RGD:6480464 CTD
G Npat nuclear protein in the AT region GBrowse link increases expression ISO 9 53,345,152 53,383,732 RGD:6480464 CTD
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 GBrowse link increases expression ISO 15 101,097,277 101,105,226 RGD:6480464 CTD
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 GBrowse link increases expression ISO 2 56,959,637 56,976,414 RGD:6480464 CTD
G Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 GBrowse link multiple interactions ISO 3 87,582,166 87,599,084 RGD:6480464 CTD
G Pgf placental growth factor GBrowse link increases expression ISO 12 86,507,591 86,518,235 RGD:6480464 CTD
G Phf20l1 PHD finger protein 20-like 1 GBrowse link decreases expression ISO 15 66,409,134 66,476,817 RGD:6480464 CTD
G Plcg1 phospholipase C, gamma 1 GBrowse link increases cleavage ISO 2 160,557,046 160,601,496 RGD:6480464 CTD
G Plk2 polo-like kinase 2 GBrowse link increases expression ISO 13 111,185,252 111,191,052 RGD:6480464 CTD
G Ptk2 PTK2 protein tyrosine kinase 2 GBrowse link increases response to substance ISO 15 73,035,535 73,253,621 RGD:6480464 CTD
G Ptk2 PTK2 protein tyrosine kinase 2 GBrowse link multiple interactions ISO 15 73,035,535 73,253,621 RGD:6480464 CTD
G Rrad Ras-related associated with diabetes GBrowse link increases expression ISO 8 107,151,966 107,155,221 RGD:6480464 CTD
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 GBrowse link increases expression ISO 5 137,537,374 137,548,142 RGD:6480464 CTD
G Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 GBrowse link increases expression ISO 7 106,493,885 106,501,749 RGD:6480464 CTD
G Slc1a1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 GBrowse link increases expression EXP 19 28,909,656 28,988,450 RGD:6480464 CTD
G Tmod2 tropomodulin 2 GBrowse link increases expression ISO 9 75,413,428 75,459,132 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link increases secretion ISO 17 35,336,335 35,338,941 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 17 35,336,335 35,338,941 RGD:6480464 CTD
G Top2a topoisomerase (DNA) II alpha GBrowse link decreases activity ISO 11 98,854,261 98,885,503 RGD:6480464 CTD
G Upp1 uridine phosphorylase 1 GBrowse link increases expression ISO 11 9,018,011 9,036,173 RGD:6480464 CTD
G Xiap X-linked inhibitor of apoptosis GBrowse link affects expression ISO X 39,421,013 39,462,841 RGD:6480464 CTD
G Xiap X-linked inhibitor of apoptosis GBrowse link multiple interactions ISO X 39,421,013 39,462,841 RGD:6480464 CTD
G Xiap X-linked inhibitor of apoptosis GBrowse link decreases expression ISO X 39,421,013 39,462,841 RGD:6480464 CTD
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 500591
    role 490275
      biological role 488424
        antimicrobial agent 46272
          disinfectant 3231
            thimerosal 105
Path 2
Term Annotations click to browse term
  CHEBI ontology 500591
    subatomic particle 499508
      composite particle 499508
        hadron 499508
          baryon 499508
            nucleon 499508
              atomic nucleus 499508
                atom 499508
                  main group element atom 468781
                    p-block element atom 466276
                      carbon group element atom 417557
                        carbon atom 414040
                          organic molecular entity 414034
                            organic ion 2560
                              organic anion 532
                                carboxylic acid anion 374
                                  monocarboxylic acid anion 309
                                    benzoates 105
                                      ethylmercurithiosalicylate 105
                                        thimerosal 105
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