ONTOLOGY REPORT - ANNOTATIONS
| Term: | thiram |
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| Accession: | CHEBI:9495
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browse the term
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| Definition: | An organic disulfide that results from the formal oxidative dimerisation of N,N-dimethyldithiocarbamic acid. |
| Synonyms: | exact_synonym: | [disulfanediylbis(carbonothioylnitrilo)]tetramethane |
| | related_synonym: | Arasan; Bis(dimethyl-thiocarbamoyl)-disulfid; C6H12N2S4; CN(C)C(=S)SSC(=S)N(C)C; InChI=1S/C6H12N2S4/c1-7(2)5(9)11-12-6(10)8(3)4/h1-4H3; InChIKey=KUAZQDVKQLNFPE-UHFFFAOYSA-N; N,N'-(dithiodicarbonothioyl)bis(N-methylmethanamine); N,N-tetramethylthiuram disulfide; Nomersan; Pomarsol; Rezifilm; TMTD; Tetramethyl-thiram disulfid; Tetramethylthioperoxydicarbonic diamide; [Me2NC(S)S]2; alpha,alpha'-dithiobis(dimethylthio)formamide; bis((dimethylamino)carbonothioyl) disulfide; bis(dimethyl thiocarbamoyl)disulfide; bis(dimethylthiocarbamoyl) disulfide; disulfure de tetramethylthiourame; tetramethylenethiuram disulfide; tetramethylthiuram disulfide; tetramethylthiurane disulfide; tetrathiuram disulfide; thirame; thiramum; thiuram |
| | xref_casrn: | 137-26-8 |
| | xref: | ChEMBL:298725 "ChEMBL COMPOUND"; ChemIDplus:137-26-8 "CAS Registry Number"; CiteXplore:14587840 "PubMed citation"; CiteXplore:1842585 "PubMed citation"; CiteXplore:20940038 "PubMed citation"; CiteXplore:3055654 "PubMed citation"; CiteXplore:3176026 "PubMed citation"; KEGG COMPOUND:137-26-8 "CAS Registry Number"; KEGG COMPOUND:C11160 "KEGG COMPOUND"; KEGG DRUG:D06114 "KEGG DRUG" |
| | xref_mesh: | MESH:D013893 |
| | xref: | NIST Chemistry WebBook:137-26-8 "CAS Registry Number"; Reaxys:1725821 "Reaxys Registry Number" |
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thiram
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| G |
Akr1c2 |
aldo-keto reductase family 1, member C2 |
|
increases activity |
ISO |
17 |
77,034,737 |
77,081,406 |
RGD:6480464 |
CTD |
| G |
Ccr2 |
chemokine (C-C motif) receptor 2 |
|
decreases expression |
ISO |
8 |
128,892,784 |
128,893,905 |
RGD:6480464 |
CTD |
| G |
Cd86 |
CD86 molecule |
|
increases expression |
ISO |
11 |
66,215,233 |
66,238,882 |
RGD:6480464 |
CTD |
| G |
Creb1 |
cAMP responsive element binding protein 1 |
|
increases expression |
ISO |
9 |
63,170,785 |
63,234,727 |
RGD:6480464 |
CTD |
| G |
Crem |
cAMP responsive element modulator |
|
increases expression |
ISO |
17 |
62,770,633 |
62,837,670 |
RGD:6480464 |
CTD |
| G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
|
increases metabolic processing |
EXP |
1 |
200,918,521 |
200,928,919 |
RGD:6480464 |
CTD |
| G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
|
multiple interactions |
EXP |
1 |
200,918,521 |
200,928,919 |
RGD:6480464 |
CTD |
| G |
Hsd11b2 |
hydroxysteroid 11-beta dehydrogenase 2 |
|
multiple interactions |
ISO |
19 |
35,336,342 |
35,341,585 |
RGD:6480464 |
CTD |
| G |
Hsd11b2 |
hydroxysteroid 11-beta dehydrogenase 2 |
|
multiple interactions |
ISO |
19 |
35,336,342 |
35,341,585 |
RGD:6480464 |
CTD |
| G |
Hsd11b2 |
hydroxysteroid 11-beta dehydrogenase 2 |
|
decreases activity |
ISO |
19 |
35,336,342 |
35,341,585 |
RGD:6480464 |
CTD |
| G |
Hsd11b2 |
hydroxysteroid 11-beta dehydrogenase 2 |
|
decreases activity |
ISO |
19 |
35,336,342 |
35,341,585 |
RGD:6480464 |
CTD |
| G |
Hsd11b2 |
hydroxysteroid 11-beta dehydrogenase 2 |
|
multiple interactions |
ISO |
19 |
35,336,342 |
35,341,585 |
RGD:6480464 |
CTD |
| G |
Hsd11b2 |
hydroxysteroid 11-beta dehydrogenase 2 |
|
decreases activity |
ISO |
19 |
35,336,342 |
35,341,585 |
RGD:6480464 |
CTD |
| G |
Ifng |
interferon gamma |
|
increases expression |
ISO |
7 |
57,621,756 |
57,625,792 |
RGD:6480464 |
CTD |
| G |
Il4 |
interleukin 4 |
|
increases expression |
ISO |
10 |
39,074,582 |
39,080,134 |
RGD:6480464 |
CTD |
| G |
Nampt |
nicotinamide phosphoribosyltransferase |
|
increases expression |
ISO |
6 |
51,129,160 |
51,166,514 |
RGD:6480464 |
CTD |
| G |
Nfkb1 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
|
decreases expression |
ISO |
2 |
233,091,013 |
233,187,501 |
RGD:6480464 |
CTD |
| G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
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multiple interactions |
ISO |
18 |
32,371,496 |
32,459,145 |
RGD:6480464 |
CTD |
| G |
Prkca |
protein kinase C, alpha |
|
decreases activity |
ISO |
10 |
97,367,196 |
97,638,910 |
RGD:6480464 |
CTD |
| G |
Prkcb |
protein kinase C, beta |
|
decreases activity |
ISO |
1 |
181,117,512 |
181,459,856 |
RGD:6480464 |
CTD |
| G |
Prkcd |
protein kinase C, delta |
|
increases activity |
ISO |
16 |
5,954,218 |
5,975,743 |
RGD:6480464 |
CTD |
| G |
Prkce |
protein kinase C, epsilon |
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decreases activity |
ISO |
6 |
9,631,234 |
10,097,311 |
RGD:6480464 |
CTD |
| G |
Prkcg |
protein kinase C, gamma |
|
decreases activity |
ISO |
1 |
64,145,749 |
64,172,712 |
RGD:6480464 |
CTD |
| G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
|
increases expression |
ISO |
13 |
64,427,288 |
64,432,978 |
RGD:6480464 |
CTD |
| G |
Sftpa1 |
surfactant protein A1 |
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multiple interactions |
ISO |
16 |
17,570,887 |
17,574,389 |
RGD:6480464 |
CTD |
| G |
Sftpb |
surfactant protein B |
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multiple interactions |
ISO |
4 |
105,609,410 |
105,618,452 |
RGD:6480464 |
CTD |
| G |
Tnf |
tumor necrosis factor |
|
increases expression |
ISO |
20 |
3,661,000 |
3,663,618 |
RGD:6480464 |
CTD |
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