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Term:sulfasalazine
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Accession:CHEBI:9334 term browser browse the term
Definition:An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Synonyms:exact_synonym: 2-hydroxy-5-{[4-(pyridin-2-ylsulfamoyl)phenyl]diazenyl}benzoic acid
 related_synonym: 2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acid;   2-Hydroxy-5-[4-(pyridin-2-ylsulfamoyl)-phenylazo]-benzoic acid;   4-(Pyridyl-2-amidosulfonyl)-3'-carboxy-4'-hydroxyazobenzene;   5-((p-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid;   5-(4-(2-Pyridylsulfamoyl)phenylazo)-2-hydroxybenzoic acid;   5-(p-(2-Pyridylsulfamyl)phenylazo)salicylic acid;   Azulfidine;   C18H14N4O5S;   InChI=1S/C18H14N4O5S/c23-16-9-6-13(11-15(16)18(24)25)21-20-12-4-7-14(8-5-12)28(26,27)22-17-3-1-2-10-19-17/h1-11,23H,(H,19,22)(H,24,25)/b21-20+;   InChIKey=NCEXYHBECQHGNR-QZQOTICOSA-N;   OC(=O)c1cc(ccc1O)\\N=N\\c1ccc(cc1)S(=O)(=O)Nc1ccccn1;   Salazosulfapiridina;   Salazosulfapyridine;   Salazosulfapyridinum;   Salicylazosulfapyridine;   Sulfasalazina;   Sulfasalazinum
 alt_id: CHEBI:101223
 xref_casrn: 599-79-1
 xref: Beilstein:356241 "Beilstein Registry Number";   Beilstein:8132868 "Beilstein Registry Number";   ChemIDplus:599-79-1 "CAS Registry Number";   CiteXplore:2434548 "PubMed citation";   DrugBank:DB00795 "DrugBank";   Gmelin:2666050 "Gmelin Registry Number";   KEGG COMPOUND:599-79-1 "CAS Registry Number";   KEGG COMPOUND:C07316 "KEGG COMPOUND";   KEGG DRUG:D00448 "KEGG DRUG"
 xref_mesh: MESH:D012460
 xref: Patent:US2396145 "Patent";   Reaxys:8132868 "Reaxys Registry Number"

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sulfasalazine term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Aadat aminoadipate aminotransferase GBrowse link increases expression ISO 16 32,845,006 32,885,600 RGD:6480464 CTD
G Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 multiple interactions EXP RGD:6480464 CTD
G Abcg2 ATP-binding cassette, subfamily G (WHITE), member 2 GBrowse link increases transport ISO 4 87,502,584 87,560,017 RGD:6480464 CTD
G Abcg2 ATP-binding cassette, subfamily G (WHITE), member 2 GBrowse link affects transport ISO 4 87,502,584 87,560,017 RGD:6480464 CTD
G Abcg2 ATP-binding cassette, subfamily G (WHITE), member 2 GBrowse link multiple interactions ISO 4 87,502,584 87,560,017 RGD:6480464 CTD
G Abcg2 ATP-binding cassette, subfamily G (WHITE), member 2 GBrowse link decreases methylation ISO 4 87,502,584 87,560,017 RGD:6480464 CTD
G Abcg2 ATP-binding cassette, subfamily G (WHITE), member 2 GBrowse link affects transport ISO 4 87,502,584 87,560,017 RGD:6480464 CTD
G Abcg2 ATP-binding cassette, subfamily G (WHITE), member 2 GBrowse link multiple interactions ISO 4 87,502,584 87,560,017 RGD:6480464 CTD
G Abcg2 ATP-binding cassette, subfamily G (WHITE), member 2 GBrowse link increases transport ISO 4 87,502,584 87,560,017 RGD:6480464 CTD
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 GBrowse link affects localization ISO X 134,868,878 134,908,166 RGD:6480464 CTD
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 GBrowse link multiple interactions ISO X 134,868,878 134,908,166 RGD:6480464 CTD
G Alpi alkaline phosphatase, intestinal GBrowse link multiple interactions EXP 9 85,892,887 85,896,353 RGD:6480464 CTD
G Anxa2 annexin A2 GBrowse link increases expression ISO 8 73,897,618 73,934,041 RGD:6480464 CTD
G Azin1 antizyme inhibitor 1 GBrowse link increases expression ISO 7 74,159,130 74,189,447 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link affects localization ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link multiple interactions ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link multiple interactions ISO 5 160,704,234 160,721,796 RGD:6480464 CTD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link increases cleavage ISO 5 160,704,234 160,721,796 RGD:6480464 CTD
G Cat catalase GBrowse link increases activity EXP 3 88,654,077 88,686,212 RGD:6480464 CTD
G Cav1 caveolin 1, caveolae protein GBrowse link multiple interactions ISO 4 42,956,102 42,989,057 RGD:6480464 CTD
G Ccnd1 cyclin D1 GBrowse link multiple interactions ISO 1 205,357,235 205,366,757 RGD:6480464 CTD
G Ccnd1 cyclin D1 GBrowse link decreases expression EXP 1 205,357,235 205,366,757 RGD:6480464 CTD
G Ccng1 cyclin G1 GBrowse link increases expression ISO 10 25,776,380 25,782,754 RGD:6480464 CTD
G Cd46 CD46 molecule, complement regulatory protein GBrowse link decreases expression EXP 13 110,972,812 111,003,407 RGD:6480464 CTD
G Cd55 Cd55 molecule GBrowse link decreases expression EXP 13 43,322,246 43,348,334 RGD:6480464 CTD
G Cd55 Cd55 molecule GBrowse link decreases expression EXP 13 43,322,246 43,348,334 RGD:6480464 CTD
G Cd59 CD59 molecule, complement regulatory protein GBrowse link decreases expression EXP 3 89,243,600 89,245,129 RGD:6480464 CTD
G Cd59 CD59 molecule, complement regulatory protein GBrowse link decreases expression EXP 3 89,243,600 89,245,129 RGD:6480464 CTD
G Cd59 CD59 molecule, complement regulatory protein GBrowse link decreases expression EXP 3 89,243,600 89,245,129 RGD:6480464 CTD
G Cdh1 cadherin 1 GBrowse link multiple interactions ISO 19 36,442,693 36,512,091 RGD:6480464 CTD
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link multiple interactions EXP 20 7,376,325 7,386,778 RGD:6480464 CTD
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link increases expression EXP 20 7,376,325 7,386,778 RGD:6480464 CTD
G Clu clusterin GBrowse link increases expression ISO 15 45,365,779 45,405,314 RGD:6480464 CTD
G Col1a1 collagen, type I, alpha 1 GBrowse link multiple interactions EXP 10 83,622,438 83,639,368 RGD:6480464 CTD
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) GBrowse link multiple interactions ISO 10 39,665,850 39,667,831 RGD:6480464 CTD
G Ctnnb1 catenin (cadherin associated protein), beta 1 GBrowse link multiple interactions ISO 8 125,978,161 125,987,670 RGD:6480464 CTD
G Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) GBrowse link multiple interactions ISO 14 18,690,339 18,692,118 RGD:6480464 CTD
G Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) GBrowse link affects secretion ISO 14 18,690,339 18,692,118 RGD:6480464 CTD
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 GBrowse link increases expression EXP 8 61,462,207 61,468,237 RGD:6480464 CTD
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 decreases expression ISO RGD:6480464 CTD
G Ddit3 DNA-damage inducible transcript 3 GBrowse link increases expression ISO 7 67,247,749 67,252,571 RGD:6480464 CTD
G Dio1 deiodinase, iodothyronine, type I GBrowse link multiple interactions ISO 5 128,385,702 128,404,015 RGD:6480464 CTD
G Dio2 deiodinase, iodothyronine, type II GBrowse link multiple interactions ISO 6 114,307,758 114,317,563 RGD:6480464 CTD
G Dio2 deiodinase, iodothyronine, type II GBrowse link multiple interactions EXP 6 114,307,758 114,317,563 RGD:6480464 CTD
G Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 GBrowse link increases expression ISO 19 22,853,702 22,871,846 RGD:6480464 CTD
G Egf epidermal growth factor GBrowse link increases expression ISO 2 227,103,900 227,195,062 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link multiple interactions ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Ephx1 epoxide hydrolase 1, microsomal (xenobiotic) GBrowse link increases expression ISO 13 96,722,973 96,752,940 RGD:6480464 CTD
G F3 coagulation factor III (thromboplastin, tissue factor) GBrowse link multiple interactions ISO 2 218,371,050 218,382,645 RGD:6480464 CTD
G Fabp4 fatty acid binding protein 4, adipocyte GBrowse link increases expression ISO 2 93,536,133 93,540,734 RGD:6480464 CTD
G Fga fibrinogen alpha chain GBrowse link increases expression ISO 2 174,737,640 174,753,598 RGD:6480464 CTD
G Ftl ferritin, light polypeptide GBrowse link increases expression ISO 1 95,929,248 95,931,092 RGD:6480464 CTD
G Gadd45b growth arrest and DNA-damage-inducible, beta GBrowse link decreases expression EXP 7 10,289,073 10,291,102 RGD:6480464 CTD
G Gdnf glial cell derived neurotrophic factor GBrowse link multiple interactions ISO 2 57,399,312 57,424,030 RGD:6480464 CTD
G Gsr glutathione reductase GBrowse link decreases activity EXP 16 62,255,562 62,298,458 RGD:6480464 CTD
G Gsta5 glutathione S-transferase alpha 5 GBrowse link increases expression EXP 8 83,202,554 83,211,997 RGD:6480464 CTD
G Gstp1 glutathione S-transferase pi 1 GBrowse link decreases expression EXP 1 206,627,398 206,629,866 RGD:6480464 CTD
G Hgf hepatocyte growth factor GBrowse link multiple interactions ISO 4 14,864,357 14,932,513 RGD:6480464 CTD
G Hif1a hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) GBrowse link multiple interactions ISO 6 96,419,024 96,463,891 RGD:6480464 CTD
G Hif1a hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) GBrowse link increases activity ISO 6 96,419,024 96,463,891 RGD:6480464 CTD
G Hint1 histidine triad nucleotide binding protein 1 GBrowse link increases expression ISO 10 40,271,895 40,275,640 RGD:6480464 CTD
G Hmgb1 high mobility group box 1 increases expression EXP RGD:6480464 CTD
G Hmox1 heme oxygenase (decycling) 1 GBrowse link increases response to substance EXP 19 13,963,139 13,969,960 RGD:6480464 CTD
G Hmox1 heme oxygenase (decycling) 1 GBrowse link multiple interactions EXP 19 13,963,139 13,969,960 RGD:6480464 CTD
G Hmox1 heme oxygenase (decycling) 1 GBrowse link increases expression EXP 19 13,963,139 13,969,960 RGD:6480464 CTD
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 GBrowse link increases expression ISO 18 45,157,435 45,251,606 RGD:6480464 CTD
G Hsd3b5 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 GBrowse link increases expression ISO 2 193,249,949 193,269,979 RGD:6480464 CTD
G Hspa1a heat shock protein 1A GBrowse link increases expression ISO 20 3,945,716 3,959,552 RGD:6480464 CTD
G Hspa1a heat shock protein 1A GBrowse link increases expression ISO 20 3,945,716 3,959,552 RGD:6480464 CTD
G Hspa1b heat shock protein 1B GBrowse link decreases expression EXP 20 3,955,274 3,957,748 RGD:6480464 CTD
G Icam1 intercellular adhesion molecule 1 GBrowse link decreases expression ISO 8 20,040,177 20,051,939 RGD:6480464 CTD
G Icam1 intercellular adhesion molecule 1 GBrowse link increases expression ISO 8 20,040,177 20,051,939 RGD:6480464 CTD
G Icam1 intercellular adhesion molecule 1 GBrowse link multiple interactions ISO 8 20,040,177 20,051,939 RGD:6480464 CTD
G Icam1 intercellular adhesion molecule 1 GBrowse link decreases expression EXP 8 20,040,177 20,051,939 RGD:6480464 CTD
G Icam1 intercellular adhesion molecule 1 GBrowse link decreases expression ISO 8 20,040,177 20,051,939 RGD:6480464 CTD
G Idh3B isocitrate dehydrogenase 3 (NAD+) beta GBrowse link increases expression ISO 3 117,892,614 117,897,633 RGD:6480464 CTD
G Ido1 indoleamine 2,3-dioxygenase 1 GBrowse link multiple interactions ISO 16 71,866,340 71,878,373 RGD:6480464 CTD
G Ifng interferon gamma GBrowse link multiple interactions ISO 7 57,621,756 57,625,792 RGD:6480464 CTD
G Ifng interferon gamma GBrowse link multiple interactions ISO 7 57,621,756 57,625,792 RGD:6480464 CTD
G Ifng interferon gamma GBrowse link multiple interactions ISO 7 57,621,756 57,625,792 RGD:6480464 CTD
G Igfbp3 insulin-like growth factor binding protein 3 GBrowse link affects expression EXP 14 87,959,153 87,967,085 RGD:6480464 CTD
G Ikbkb inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta GBrowse link decreases expression ISO 16 73,804,730 73,858,510 RGD:6480464 CTD
G Il10 interleukin 10 GBrowse link multiple interactions ISO 13 43,953,900 43,957,766 RGD:6480464 CTD
G Il10 interleukin 10 GBrowse link multiple interactions EXP 13 43,953,900 43,957,766 RGD:6480464 CTD
G Il12a interleukin 12A GBrowse link multiple interactions ISO 2 158,710,261 158,717,689 RGD:6480464 CTD
G Il12b interleukin 12B GBrowse link multiple interactions ISO 10 29,558,955 29,568,331 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link multiple interactions ISO 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link multiple interactions ISO 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link decreases expression ISO 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link multiple interactions ISO 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link multiple interactions EXP 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link decreases expression ISO 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link multiple interactions EXP 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link multiple interactions EXP 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link multiple interactions ISO 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link multiple interactions EXP 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il1rn interleukin 1 receptor antagonist GBrowse link multiple interactions EXP 3 2,607,800 2,613,216 RGD:6480464 CTD
G Il2 interleukin 2 GBrowse link multiple interactions ISO 2 123,655,005 123,659,709 RGD:6480464 CTD
G Il2ra interleukin 2 receptor, alpha GBrowse link multiple interactions ISO 17 78,050,491 78,097,802 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link multiple interactions ISO 4 456,799 461,376 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link multiple interactions ISO 4 456,799 461,376 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link multiple interactions ISO 4 456,799 461,376 RGD:6480464 CTD
G Insr insulin receptor GBrowse link increases expression ISO 12 2,934,967 3,087,691 RGD:6480464 CTD
G Itgam integrin, alpha M GBrowse link multiple interactions ISO 1 187,334,413 187,385,583 RGD:6480464 CTD
G Itgb2 integrin, beta 2 GBrowse link multiple interactions ISO 20 11,446,521 11,485,009 RGD:6480464 CTD
G Mapk9 mitogen-activated protein kinase 9 GBrowse link increases phosphorylation EXP 10 35,353,486 35,384,319 RGD:6480464 CTD
G Mmp2 matrix metallopeptidase 2 GBrowse link multiple interactions EXP 19 15,246,036 15,275,061 RGD:6480464 CTD
G Mmp9 matrix metallopeptidase 9 GBrowse link multiple interactions ISO 3 155,985,473 155,993,433 RGD:6480464 CTD
G Mmp9 matrix metallopeptidase 9 GBrowse link multiple interactions EXP 3 155,985,473 155,993,433 RGD:6480464 CTD
G Mpo myeloperoxidase GBrowse link multiple interactions EXP 10 76,085,872 76,097,012 RGD:6480464 CTD
G Mpo myeloperoxidase GBrowse link decreases activity EXP 10 76,085,872 76,097,012 RGD:6480464 CTD
G Mpo myeloperoxidase GBrowse link multiple interactions EXP 10 76,085,872 76,097,012 RGD:6480464 CTD
G Mthfr methylenetetrahydrofolate reductase (NAD(P)H) GBrowse link increases response to substance ISO 5 165,112,850 165,126,885 RGD:6480464 CTD
G Nat2 N-acetyltransferase 2 (arylamine N-acetyltransferase) GBrowse link affects metabolic processing ISO 16 23,855,555 23,876,531 RGD:6480464 CTD
G Nat2 N-acetyltransferase 2 (arylamine N-acetyltransferase) GBrowse link affects metabolic processing ISO 16 23,855,555 23,876,531 RGD:6480464 CTD
G Nat2 N-acetyltransferase 2 (arylamine N-acetyltransferase) GBrowse link affects response to substance ISO 16 23,855,555 23,876,531 RGD:6480464 CTD
G Nat2 N-acetyltransferase 2 (arylamine N-acetyltransferase) GBrowse link increases metabolic processing ISO 16 23,855,555 23,876,531 RGD:6480464 CTD
G Nat2 N-acetyltransferase 2 (arylamine N-acetyltransferase) GBrowse link increases acetylation ISO 16 23,855,555 23,876,531 RGD:6480464 CTD
G Nat2 N-acetyltransferase 2 (arylamine N-acetyltransferase) GBrowse link affects response to substance ISO 16 23,855,555 23,876,531 RGD:6480464 CTD
G Nat2 N-acetyltransferase 2 (arylamine N-acetyltransferase) GBrowse link affects response to substance ISO 16 23,855,555 23,876,531 RGD:6480464 CTD
G Nat2 N-acetyltransferase 2 (arylamine N-acetyltransferase) GBrowse link affects response to substance ISO 16 23,855,555 23,876,531 RGD:6480464 CTD
G Nat2 N-acetyltransferase 2 (arylamine N-acetyltransferase) GBrowse link affects response to substance ISO 16 23,855,555 23,876,531 RGD:6480464 CTD
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 GBrowse link multiple interactions ISO 3 58,366,693 58,394,116 RGD:6480464 CTD
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 GBrowse link multiple interactions EXP 3 58,366,693 58,394,116 RGD:6480464 CTD
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 GBrowse link multiple interactions ISO 2 233,091,013 233,187,501 RGD:6480464 CTD
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 GBrowse link multiple interactions ISO 2 233,091,013 233,187,501 RGD:6480464 CTD
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 GBrowse link decreases expression ISO 2 233,091,013 233,187,501 RGD:6480464 CTD
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 GBrowse link decreases localization EXP 2 233,091,013 233,187,501 RGD:6480464 CTD
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha GBrowse link multiple interactions ISO 6 75,729,302 75,732,475 RGD:6480464 CTD
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha GBrowse link decreases expression ISO 6 75,729,302 75,732,475 RGD:6480464 CTD
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha GBrowse link decreases phosphorylation ISO 6 75,729,302 75,732,475 RGD:6480464 CTD
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha GBrowse link increases degradation ISO 6 75,729,302 75,732,475 RGD:6480464 CTD
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha GBrowse link multiple interactions ISO 6 75,729,302 75,732,475 RGD:6480464 CTD
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha GBrowse link decreases expression ISO 6 75,729,302 75,732,475 RGD:6480464 CTD
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha GBrowse link multiple interactions EXP 6 75,729,302 75,732,475 RGD:6480464 CTD
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha GBrowse link decreases phosphorylation EXP 6 75,729,302 75,732,475 RGD:6480464 CTD
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha GBrowse link multiple interactions EXP 6 75,729,302 75,732,475 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link multiple interactions ISO 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link multiple interactions ISO 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link multiple interactions EXP 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link decreases expression EXP 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link multiple interactions ISO 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link multiple interactions EXP 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link increases expression EXP 19 37,251,147 37,266,040 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link increases expression ISO 19 37,251,147 37,266,040 RGD:6480464 CTD
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 GBrowse link increases expression ISO 18 32,371,496 32,459,145 RGD:6480464 CTD
G Oat ornithine aminotransferase GBrowse link increases expression ISO 1 192,026,623 192,046,404 RGD:6480464 CTD
G Odc1 ornithine decarboxylase 1 GBrowse link increases expression ISO 6 41,309,211 41,315,796 RGD:6480464 CTD
G Oprm1 opioid receptor, mu 1 GBrowse link multiple interactions ISO 1 37,535,416 37,779,392 RGD:6480464 CTD
G Pcna proliferating cell nuclear antigen GBrowse link increases expression ISO 3 120,008,715 120,012,589 RGD:6480464 CTD
G Pgam2 phosphoglycerate mutase 2 (muscle) GBrowse link increases expression ISO 14 86,466,055 86,468,166 RGD:6480464 CTD
G Pla2g1b phospholipase A2, group IB, pancreas GBrowse link multiple interactions ISO 12 42,405,475 42,415,189 RGD:6480464 CTD
G Potef POTE ankyrin domain family, member F GBrowse link multiple interactions EXP 18 24,420,779 24,422,284 RGD:6480464 CTD
G Pparg peroxisome proliferator-activated receptor gamma GBrowse link increases expression EXP 4 151,492,220 151,617,331 RGD:6480464 CTD
G Prdx1 peroxiredoxin 1 GBrowse link increases expression EXP 5 136,975,780 136,991,630 RGD:6480464 CTD
G Prdx1 peroxiredoxin 1 GBrowse link increases expression ISO 5 136,975,780 136,991,630 RGD:6480464 CTD
G Prdx1l1 peroxiredoxin 1-like 1 GBrowse link increases expression EXP 2 201,373,420 201,374,019 RGD:6480464 CTD
G Prdx3 peroxiredoxin 3 GBrowse link increases expression ISO 1 267,468,371 267,481,273 RGD:6480464 CTD
G Psmb9 proteasome (prosome, macropain) subunit, beta type, 9 GBrowse link decreases expression EXP 20 4,801,187 4,806,608 RGD:6480464 CTD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link decreases expression EXP 13 64,427,288 64,432,978 RGD:6480464 CTD
G Ptpmt1 protein tyrosine phosphatase, mitochondrial 1 GBrowse link increases expression ISO 3 75,269,658 75,279,872 RGD:6480464 CTD
G Rbp4 retinol binding protein 4, plasma GBrowse link affects expression ISO 1 242,443,795 242,450,997 RGD:6480464 CTD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link multiple interactions ISO 1 208,262,669 208,273,148 RGD:6480464 CTD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link multiple interactions ISO 1 208,262,669 208,273,148 RGD:6480464 CTD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link multiple interactions ISO 1 208,262,669 208,273,148 RGD:6480464 CTD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link multiple interactions ISO 1 208,262,669 208,273,148 RGD:6480464 CTD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link decreases activity ISO 1 208,262,669 208,273,148 RGD:6480464 CTD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link multiple interactions ISO 1 208,262,669 208,273,148 RGD:6480464 CTD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link multiple interactions ISO 1 208,262,669 208,273,148 RGD:6480464 CTD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link increases localization ISO 1 208,262,669 208,273,148 RGD:6480464 CTD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link multiple interactions ISO 1 208,262,669 208,273,148 RGD:6480464 CTD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link affects localization EXP 1 208,262,669 208,273,148 RGD:6480464 CTD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link multiple interactions EXP 1 208,262,669 208,273,148 RGD:6480464 CTD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link decreases localization EXP 1 208,262,669 208,273,148 RGD:6480464 CTD
G Ripk2 receptor-interacting serine-threonine kinase 2 GBrowse link multiple interactions ISO 5 30,714,817 30,745,941 RGD:6480464 CTD
G RT1-Bb RT1 class II, locus Bb GBrowse link affects expression EXP 20 4,730,559 4,736,201 RGD:6480464 CTD
G Sele selectin E GBrowse link increases expression ISO 13 79,813,455 79,822,845 RGD:6480464 CTD
G Serpinc1 serpin peptidase inhibitor, clade C (antithrombin), member 1 GBrowse link increases expression ISO 13 76,548,456 76,562,724 RGD:6480464 CTD
G Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 GBrowse link multiple interactions ISO 1 211,375,889 211,390,313 RGD:6480464 CTD
G Slc46a1 solute carrier family 46 (folate transporter), member 1 GBrowse link multiple interactions ISO 10 64,576,068 64,582,504 RGD:6480464 CTD
G Slc46a1 solute carrier family 46 (folate transporter), member 1 GBrowse link decreases activity ISO 10 64,576,068 64,582,504 RGD:6480464 CTD
G Slc46a1 solute carrier family 46 (folate transporter), member 1 GBrowse link multiple interactions EXP 10 64,576,068 64,582,504 RGD:6480464 CTD
G Slc46a1 solute carrier family 46 (folate transporter), member 1 GBrowse link decreases activity ISO 10 64,576,068 64,582,504 RGD:6480464 CTD
G Slc7a11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 GBrowse link decreases activity ISO 2 139,241,142 139,317,101 RGD:6480464 CTD
G Slc7a11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 GBrowse link multiple interactions ISO 2 139,241,142 139,317,101 RGD:6480464 CTD
G Slc7a11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 GBrowse link multiple interactions ISO 2 139,241,142 139,317,101 RGD:6480464 CTD
G Slc7a11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 GBrowse link decreases activity ISO 2 139,241,142 139,317,101 RGD:6480464 CTD
G Sod1 superoxide dismutase 1, soluble GBrowse link increases expression ISO 11 29,810,766 29,816,342 RGD:6480464 CTD
G Spp1 secreted phosphoprotein 1 increases expression ISO RGD:6480464 CTD
G Tbxas1 thromboxane A synthase 1, platelet GBrowse link multiple interactions ISO 4 66,502,253 66,677,538 RGD:6480464 CTD
G Tbxas1 thromboxane A synthase 1, platelet GBrowse link decreases activity ISO 4 66,502,253 66,677,538 RGD:6480464 CTD
G Tdo2 tryptophan 2,3-dioxygenase GBrowse link multiple interactions ISO 2 173,594,020 173,611,833 RGD:6480464 CTD
G Thra thyroid hormone receptor alpha GBrowse link multiple interactions ISO 10 87,514,443 87,542,306 RGD:6480464 CTD
G Thra thyroid hormone receptor alpha GBrowse link decreases expression ISO 10 87,514,443 87,542,306 RGD:6480464 CTD
G Thrb thyroid hormone receptor beta GBrowse link multiple interactions ISO 15 9,282,845 9,345,506 RGD:6480464 CTD
G Timp1 TIMP metallopeptidase inhibitor 1 GBrowse link multiple interactions EXP X 12,542,496 12,547,094 RGD:6480464 CTD
G Timp2 TIMP metallopeptidase inhibitor 2 GBrowse link increases expression ISO 10 108,310,473 108,358,821 RGD:6480464 CTD
G Timp3 TIMP metallopeptidase inhibitor 3 GBrowse link increases expression ISO 7 19,677,144 19,727,072 RGD:6480464 CTD
G Tlr2 toll-like receptor 2 GBrowse link multiple interactions ISO 2 175,607,990 175,613,992 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link increases response to substance ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link decreases expression EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link decreases secretion EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link decreases expression ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b GBrowse link increases secretion ISO 7 90,606,424 90,634,431 RGD:6480464 CTD
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 GBrowse link decreases expression ISO 15 59,397,837 59,428,014 RGD:6480464 CTD
G Tpm3 tropomyosin 3 GBrowse link decreases expression ISO 2 182,303,994 182,324,994 RGD:6480464 CTD
G Ubc ubiquitin C GBrowse link increases expression ISO 12 32,333,211 32,337,944 RGD:6480464 CTD
G Vcam1 vascular cell adhesion molecule 1 GBrowse link multiple interactions ISO 2 212,277,654 212,297,376 RGD:6480464 CTD
G Vcam1 vascular cell adhesion molecule 1 GBrowse link decreases expression ISO 2 212,277,654 212,297,376 RGD:6480464 CTD
G Vcam1 vascular cell adhesion molecule 1 GBrowse link increases expression ISO 2 212,277,654 212,297,376 RGD:6480464 CTD
G Vcam1 vascular cell adhesion molecule 1 GBrowse link decreases expression EXP 2 212,277,654 212,297,376 RGD:6480464 CTD
G Vim vimentin GBrowse link increases expression ISO 17 87,847,280 87,855,763 RGD:6480464 CTD
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 492507
    role 482196
      application 245130
        pharmaceutical 173979
          drug 173776
            antiinfective agent 13578
              sulfasalazine 232
Path 2
Term Annotations click to browse term
  CHEBI ontology 492507
    subatomic particle 491470
      composite particle 491470
        hadron 491470
          baryon 491470
            nucleon 491470
              atomic nucleus 491470
                atom 491470
                  main group element atom 461139
                    p-block element atom 458635
                      chalcogen 315489
                        oxygen atom 300437
                          oxygen molecular entity 300437
                            hydroxides 224223
                              oxoacid 143467
                                chalcogen oxoacid 14790
                                  sulfur oxoacid 13411
                                    sulfonic acid 4979
                                      sulfonic acid derivative 4979
                                        sulfonamide 2302
                                          sulfanilamide 289
                                            sulfasalazine 232
paths to the root

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