ONTOLOGY REPORT - ANNOTATIONS
| Term: | sulfamethoxazole |
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| Accession: | CHEBI:9332
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browse the term
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| Definition: | An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position. |
| Synonyms: | exact_synonym: | 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide |
| | related_synonym: | 3-(p-Aminophenylsulfonamido)-5-methylisoxazole; 3-Sulfanilamido-5-methylisoxazole; 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide; C10H11N3O3S; Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1; Gantanol (TN); InChI=1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13); InChIKey=JLKIGFTWXXRPMT-UHFFFAOYSA-N; SMX |
| | alt_id: | CHEBI:102247 |
| | xref_casrn: | 723-46-6 |
| | xref: | ChEMBL:102247 "ChEMBL COMPOUND"; ChEMBL:10891117 "PubMed citation"; ChEMBL:10969989 "PubMed citation"; ChEMBL:17110110 "PubMed citation"; ChEMBL:17158933 "PubMed citation"; ChEMBL:17311370 "PubMed citation"; ChEMBL:3906132 "PubMed citation"; ChEMBL:6864729 "PubMed citation"; ChEMBL:7490723 "PubMed citation"; ChEMBL:7731020 "PubMed citation"; ChEMBL:8632413 "PubMed citation"; ChemIDplus:723-46-6 "CAS Registry Number"; CiteXplore:10843725 "PubMed citation"; CiteXplore:11350866 "PubMed citation"; CiteXplore:11431418 "PubMed citation"; CiteXplore:15588915 "PubMed citation"; CiteXplore:313909 "PubMed citation"; CiteXplore:7534104 "PubMed citation"; CiteXplore:7602118 "PubMed citation"; CiteXplore:7798534 "PubMed citation"; DrugBank:723-46-6 "CAS Registry Number"; DrugBank:DB01015 "DrugBank"; Gmelin:226453 "Gmelin Registry Number"; KEGG COMPOUND:723-46-6 "CAS Registry Number"; KEGG COMPOUND:C07315 "KEGG COMPOUND"; KEGG DRUG:D00447 "KEGG DRUG" |
| | xref_mesh: | MESH:D013420 |
| | xref: | Reaxys:226453 "Reaxys Registry Number"; Wikipedia:Sulfamethoxazole "Wikipedia" |
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sulfamethoxazole
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| G |
Alb |
albumin |
|
multiple interactions |
ISO |
14 |
19,126,935 |
19,142,214 |
RGD:6480464 |
CTD |
| G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
|
multiple interactions |
EXP |
12 |
9,517,016 |
9,541,000 |
RGD:6480464 |
CTD |
| G |
Gstp1 |
glutathione S-transferase pi 1 |
|
multiple interactions |
ISO |
1 |
206,627,398 |
206,629,866 |
RGD:6480464 |
CTD |
| G |
Ifng |
interferon gamma |
|
increases secretion |
ISO |
7 |
57,621,756 |
57,625,792 |
RGD:6480464 |
CTD |
| G |
Il5 |
interleukin 5 |
|
increases secretion |
ISO |
10 |
39,177,786 |
39,180,657 |
RGD:6480464 |
CTD |
| G |
Nat2 |
N-acetyltransferase 2 (arylamine N-acetyltransferase) |
|
increases metabolic processing |
ISO |
16 |
23,855,555 |
23,876,531 |
RGD:6480464 |
CTD |
| G |
Phyh |
phytanoyl-CoA 2-hydroxylase |
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decreases expression |
ISO |
17 |
84,418,173 |
84,435,073 |
RGD:6480464 |
CTD |
| G |
Pir |
pirin (iron-binding nuclear protein) |
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increases expression |
ISO |
X |
50,864,981 |
50,974,861 |
RGD:6480464 |
CTD |
| G |
Sod2 |
superoxide dismutase 2, mitochondrial |
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multiple interactions |
EXP |
1 |
41,862,997 |
41,870,327 |
RGD:6480464 |
CTD |
co-trimoxazole
|
| G |
Ins2 |
insulin 2 |
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increases secretion |
ISO |
1 |
202,935,548 |
202,936,379 |
RGD:6480464 |
CTD |
nitrososulfamethoxazole
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| G |
Ifng |
interferon gamma |
|
increases secretion |
ISO |
7 |
57,621,756 |
57,625,792 |
RGD:6480464 |
CTD |
| G |
Il13 |
interleukin 13 |
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increases secretion |
ISO |
10 |
39,093,512 |
39,096,069 |
RGD:6480464 |
CTD |
| G |
Il5 |
interleukin 5 |
|
increases secretion |
ISO |
10 |
39,177,786 |
39,180,657 |
RGD:6480464 |
CTD |
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