ONTOLOGY REPORT - ANNOTATIONS
| Term: | sulfadiazine |
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| Accession: | CHEBI:9328
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| Definition: | A pyrimidine compound having a 4-aminobenzenesulfonamido group at the 2-position. |
| Synonyms: | exact_synonym: | 4-amino-N-(pyrimidin-2-yl)benzenesulfonamide |
| | related_synonym: | 2-sulfanilamidopyrimidine; 2-sulfanilylaminopyrimidine; 4-amino-N-2-pyrimidinylbenzenesulfonamide; C10H10N4O2S; InChI=1S/C10H10N4O2S/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10/h1-7H,11H2,(H,12,13,14); InChIKey=SEEPANYCNGTZFQ-UHFFFAOYSA-N; N(1)-2-pyrimidinylsulfanilamide; N(1)-2-pyrimidylsulfanilamide; Nc1ccc(cc1)S(=O)(=O)Nc1ncccn1; sulfadiazina; sulfadiazinum; sulfapyrimidine; sulphadiazine |
| | xref_casrn: | 68-35-9 |
| | xref: | Beilstein:235192 "Beilstein Registry Number"; ChEMBL:102131 "ChEMBL COMPOUND"; ChemIDplus:68-35-9 "CAS Registry Number"; CiteXplore:11431418 "PubMed citation"; DrugBank:DB00359 "DrugBank"; Gmelin:219136 "Gmelin Registry Number"; KEGG COMPOUND:68-35-9 "CAS Registry Number"; KEGG COMPOUND:C07658 "KEGG COMPOUND"; KEGG DRUG:D00587 "KEGG DRUG" |
| | xref_mesh: | MESH:D013411 |
| | xref: | NIST Chemistry WebBook:68-35-9 "CAS Registry Number"; Patent:GB557055 "Patent"; Patent:US2407966 "Patent"; Patent:US2410793 "Patent"; Wikipedia:Sulfadiazine "Wikipedia" |
| | cyclic_relationship: | is_conjugate_acid_of CHEBI:33127 |
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sulfadiazine
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| G |
Cyp2c11 |
cytochrome P450, subfamily 2, polypeptide 11 |
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increases hydroxylation |
ISO |
1 |
243,281,320 |
243,320,945 |
RGD:6480464 |
CTD |
| G |
Cyp2c79 |
cytochrome P450, family 2, subfamily c, polypeptide 79 |
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increases hydroxylation |
ISO |
1 |
244,400,004 |
244,493,624 |
RGD:6480464 |
CTD |
| G |
Il6 |
interleukin 6 |
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multiple interactions |
ISO |
4 |
456,799 |
461,376 |
RGD:6480464 |
CTD |
| G |
Nat2 |
N-acetyltransferase 2 (arylamine N-acetyltransferase) |
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increases acetylation |
ISO |
16 |
23,855,555 |
23,876,531 |
RGD:6480464 |
CTD |
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