ONTOLOGY REPORT - ANNOTATIONS
Term: sirolimus
Accession: CHEBI:9168
browse the term
Definition: A macrolide isolated from Streptomyces hygroscopicus consisting of a 29-membered ring containing 4 trans double bonds, three of which are conjugated. It is an antibiotic, immunosupressive and antineoplastic agent.
Synonyms: exact_synonym: (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
related_synonym: (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-{(2S)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0(4,9)]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone; Antibiotic AY 22989; C51H79NO13; InChI=1S/C51H79NO13/c1-30-16-12-11-13-17-31(2)42(61-8)28-38-21-19-36(7)51(60,65-38)48(57)49(58)52-23-15-14-18-39(52)50(59)64-43(33(4)26-37-20-22-40(53)44(27-37)62-9)29-41(54)32(3)25-35(6)46(56)47(63-10)45(55)34(5)24-30/h11-13,16-17,25,30,32-34,36-40,42-44,46-47,53,56,60H,14-15,18-24,26-29H2,1-10H3/b13-11+,16-12+,31-17+,35-25+/t30-,32-,33+,34-,36-,37+,38+,39+,40-,42+,43+,44-,46-,47+,51-/m1/s1; InChIKey=QFJCIRLUMZQUOT-HPLJOQBZSA-N; InChIKey=QFJCIRLUMZQUOT-KLHQEZAJSA-N; Rapamune; [H][C@]1(CC[C@@H](O)[C@@H](C1)OC)C[C@H](C)[C@]1([H])CC(=O)[C@H](C)\\C=C(C)\\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\\C=C\\C=C\\C=C(C)\\[C@H](C[C@]2([H])CC[C@@H](C)[C@@](O)(O2)C(=O)C(=O)N2CCCC[C@@]2([H])C(=O)O1)OC; rapamycin; sirolimusum
alt_id: CHEBI:67812
xref_casrn: 53123-88-9
xref: ChemIDplus:53123-88-9 "CAS Registry Number"; CiteXplore:22960739 "PubMed citation"; CiteXplore:22981852 "PubMed citation"; CiteXplore:22984623 "PubMed citation"; DrugBank:DB00877 "DrugBank"; HMDB:HMDB15015 "HMDB"; KEGG COMPOUND:53123-88-9 "CAS Registry Number"; KEGG COMPOUND:C07909 "KEGG COMPOUND"; KEGG DRUG:D00753 "KEGG DRUG"; LIPID MAPS:LMPK06000003 "LIPID MAPS instance"
xref_mesh: MESH:D020123
xref: Reaxys:5848501 "Reaxys Registry Number"; Wikipedia:Rapamycin "Wikipedia"
sirolimus
G
A2M
alpha-2-macroglobulin
increases expression
ISO
12
9,220,304
9,268,558
RGD:6480464
CTD
G
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
multiple interactions
EXP
9
107,543,283
107,690,527
RGD:6480464
CTD
G
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
increases expression
EXP
9
107,543,283
107,690,527
RGD:6480464
CTD
G
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
increases expression
ISO
9
107,543,283
107,690,527
RGD:6480464
CTD
G
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
affects metabolic processing
EXP
7
87,133,179
87,342,639
RGD:6480464
CTD
G
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
affects transport
EXP
7
87,133,179
87,342,639
RGD:6480464
CTD
G
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
affects metabolic processing
EXP
7
87,133,179
87,342,639
RGD:6480464
CTD
G
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
decreases expression
ISO
10
101,542,463
101,611,662
RGD:6480464
CTD
G
ABCC8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
decreases expression
ISO
11
17,414,432
17,498,449
RGD:6480464
CTD
G
ACE2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
decreases expression
ISO
X
15,579,156
15,620,192
RGD:6480464
CTD
G
ACER2
alkaline ceramidase 2
multiple interactions
EXP
9
19,408,925
19,452,500
RGD:6480464
CTD
G
ACTA2
actin, alpha 2, smooth muscle, aorta
multiple interactions
EXP
10
90,694,831
90,751,147
RGD:6480464
CTD
G
ACTB
actin, beta
increases expression
ISO
7
5,566,779
5,570,232
RGD:6480464
CTD
G
ACTB
actin, beta
multiple interactions
ISO
7
5,566,779
5,570,232
RGD:6480464
CTD
G
AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
multiple interactions
ISO
1
230,838,269
230,850,336
RGD:6480464
CTD
G
AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
decreases expression
ISO
X
129,263,337
129,299,861
RGD:6480464
CTD
G
AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
multiple interactions
EXP
X
129,263,337
129,299,861
RGD:6480464
CTD
G
AKT1
v-akt murine thymoma viral oncogene homolog 1
multiple interactions
EXP
14
105,235,686
105,262,080
RGD:6480464
CTD
G
AKT1
v-akt murine thymoma viral oncogene homolog 1
multiple interactions
EXP
14
105,235,686
105,262,080
RGD:6480464
CTD
G
AKT1
v-akt murine thymoma viral oncogene homolog 1
decreases phosphorylation
EXP
14
105,235,686
105,262,080
RGD:6480464
CTD
G
AKT1
v-akt murine thymoma viral oncogene homolog 1
increases phosphorylation
EXP
14
105,235,686
105,262,080
RGD:6480464
CTD
G
AKT1
v-akt murine thymoma viral oncogene homolog 1
multiple interactions
ISO
14
105,235,686
105,262,080
RGD:6480464
CTD
G
AKT1
v-akt murine thymoma viral oncogene homolog 1
multiple interactions
ISO
14
105,235,686
105,262,080
RGD:6480464
CTD
G
AKT1
v-akt murine thymoma viral oncogene homolog 1
multiple interactions
EXP
14
105,235,686
105,262,080
RGD:6480464
CTD
G
AKT1
v-akt murine thymoma viral oncogene homolog 1
decreases phosphorylation
EXP
14
105,235,686
105,262,080
RGD:6480464
CTD
G
AKT2
v-akt murine thymoma viral oncogene homolog 2
multiple interactions
EXP
19
40,736,224
40,791,302
RGD:6480464
CTD
G
ANGPTL6
angiopoietin-like 6
increases expression
ISO
19
10,203,013
10,213,425
RGD:6480464
CTD
G
APP
amyloid beta (A4) precursor protein
decreases expression
EXP
21
27,252,861
27,543,446
RGD:6480464
CTD
G
APP
amyloid beta (A4) precursor protein
decreases expression
ISO
21
27,252,861
27,543,446
RGD:6480464
CTD
G
APP
amyloid beta (A4) precursor protein
increases expression
ISO
21
27,252,861
27,543,446
RGD:6480464
CTD
G
APP
amyloid beta (A4) precursor protein
increases expression
EXP
21
27,252,861
27,543,446
RGD:6480464
CTD
G
AQP2
aquaporin 2 (collecting duct)
multiple interactions
ISO
12
50,344,524
50,352,664
RGD:6480464
CTD
G
AQP2
aquaporin 2 (collecting duct)
decreases expression
ISO
12
50,344,524
50,352,664
RGD:6480464
CTD
G
AR
androgen receptor
multiple interactions
EXP
X
66,763,874
66,950,461
RGD:6480464
CTD
G
AR
androgen receptor
multiple interactions
EXP
X
66,763,874
66,950,461
RGD:6480464
CTD
G
AR
androgen receptor
increases activity
EXP
X
66,763,874
66,950,461
RGD:6480464
CTD
G
AR
androgen receptor
increases expression
EXP
X
66,763,874
66,950,461
RGD:6480464
CTD
G
ASNS
asparagine synthetase (glutamine-hydrolyzing)
multiple interactions
ISO
7
97,481,429
97,501,854
RGD:6480464
CTD
G
ATG4A
autophagy related 4A, cysteine peptidase
increases expression
ISO
X
107,334,899
107,397,901
RGD:6480464
CTD
G
ATG4B
autophagy related 4B, cysteine peptidase
increases expression
ISO
2
242,577,027
242,613,272
RGD:6480464
CTD
G
ATG5
autophagy related 5
multiple interactions
EXP
6
106,632,352
106,773,695
RGD:6480464
CTD
G
AURKB
aurora kinase B
multiple interactions
EXP
17
8,108,049
8,113,944
RGD:6480464
CTD
G
BAD
BCL2-associated agonist of cell death
multiple interactions
ISO
11
64,037,300
64,052,176
RGD:6480464
CTD
G
BAX
BCL2-associated X protein
affects localization
EXP
19
49,458,117
49,465,055
RGD:6480464
CTD
G
BAX
BCL2-associated X protein
multiple interactions
EXP
19
49,458,117
49,465,055
RGD:6480464
CTD
G
BAX
BCL2-associated X protein
increases expression
EXP
19
49,458,117
49,465,055
RGD:6480464
CTD
G
BAX
BCL2-associated X protein
multiple interactions
ISO
19
49,458,117
49,465,055
RGD:6480464
CTD
G
BAX
BCL2-associated X protein
increases expression
ISO
19
49,458,117
49,465,055
RGD:6480464
CTD
G
BBC3
BCL2 binding component 3
multiple interactions
EXP
19
47,724,079
47,736,023
RGD:6480464
CTD
G
BBC3
BCL2 binding component 3
multiple interactions
EXP
19
47,724,079
47,736,023
RGD:6480464
CTD
G
BCL2
B-cell CLL/lymphoma 2
multiple interactions
EXP
18
60,790,579
60,986,613
RGD:6480464
CTD
G
BCL2
B-cell CLL/lymphoma 2
multiple interactions
EXP
18
60,790,579
60,986,613
RGD:6480464
CTD
G
BCL2
B-cell CLL/lymphoma 2
multiple interactions
EXP
18
60,790,579
60,986,613
RGD:6480464
CTD
G
BCL2
B-cell CLL/lymphoma 2
decreases expression
EXP
18
60,790,579
60,986,613
RGD:6480464
CTD
G
BCL2
B-cell CLL/lymphoma 2
decreases expression
EXP
18
60,790,579
60,986,613
RGD:6480464
CTD
G
BCL2
B-cell CLL/lymphoma 2
multiple interactions
ISO
18
60,790,579
60,986,613
RGD:6480464
CTD
G
BCL2
B-cell CLL/lymphoma 2
multiple interactions
ISO
18
60,790,579
60,986,613
RGD:6480464
CTD
G
BCL2L1
BCL2-like 1
multiple interactions
EXP
20
30,252,261
30,310,656
RGD:6480464
CTD
G
BCL2L1
BCL2-like 1
multiple interactions
EXP
20
30,252,261
30,310,656
RGD:6480464
CTD
G
BCL2L1
BCL2-like 1
decreases expression
EXP
20
30,252,261
30,310,656
RGD:6480464
CTD
G
BCL2L1
BCL2-like 1
multiple interactions
ISO
20
30,252,261
30,310,656
RGD:6480464
CTD
G
BCL2L1
BCL2-like 1
multiple interactions
ISO
20
30,252,261
30,310,656
RGD:6480464
CTD
G
BCL2L1
BCL2-like 1
decreases expression
ISO
20
30,252,261
30,310,656
RGD:6480464
CTD
G
BCL2L1
BCL2-like 1
increases expression
ISO
20
30,252,261
30,310,656
RGD:6480464
CTD
G
BCL2L1
BCL2-like 1
increases expression
ISO
20
30,252,261
30,310,656
RGD:6480464
CTD
G
BCL2L11
BCL2-like 11 (apoptosis facilitator)
multiple interactions
EXP
2
111,878,491
111,926,022
RGD:6480464
CTD
G
BCL2L11
BCL2-like 11 (apoptosis facilitator)
increases expression
EXP
2
111,878,491
111,926,022
RGD:6480464
CTD
G
BCL2L11
BCL2-like 11 (apoptosis facilitator)
decreases expression
ISO
2
111,878,491
111,926,022
RGD:6480464
CTD
G
BDNF
brain-derived neurotrophic factor
multiple interactions
ISO
11
27,676,440
27,743,605
RGD:6480464
CTD
G
BECN1
beclin 1, autophagy related
multiple interactions
EXP
17
40,962,150
40,976,310
RGD:6480464
CTD
G
BECN1
beclin 1, autophagy related
increases expression
ISO
17
40,962,150
40,976,310
RGD:6480464
CTD
G
BID
BH3 interacting domain death agonist
multiple interactions
EXP
22
18,216,906
18,257,431
RGD:6480464
CTD
G
BID
BH3 interacting domain death agonist
multiple interactions
ISO
22
18,216,906
18,257,431
RGD:6480464
CTD
G
BID
BH3 interacting domain death agonist
decreases expression
ISO
22
18,216,906
18,257,431
RGD:6480464
CTD
G
BID
BH3 interacting domain death agonist
increases expression
ISO
22
18,216,906
18,257,431
RGD:6480464
CTD
G
BIRC2
baculoviral IAP repeat containing 2
multiple interactions
EXP
11
102,217,913
102,249,401
RGD:6480464
CTD
G
BIRC2
baculoviral IAP repeat containing 2
affects localization
ISO
11
102,217,913
102,249,401
RGD:6480464
CTD
G
BIRC2
baculoviral IAP repeat containing 2
increases expression
ISO
11
102,217,913
102,249,401
RGD:6480464
CTD
G
BIRC5
baculoviral IAP repeat containing 5
multiple interactions
EXP
17
76,210,277
76,221,716
RGD:6480464
CTD
G
BIRC5
baculoviral IAP repeat containing 5
decreases expression
EXP
17
76,210,277
76,221,716
RGD:6480464
CTD
G
BIRC5
baculoviral IAP repeat containing 5
multiple interactions
EXP
17
76,210,277
76,221,716
RGD:6480464
CTD
G
BIRC5
baculoviral IAP repeat containing 5
decreases expression
EXP
17
76,210,277
76,221,716
RGD:6480464
CTD
G
BNIP3
BCL2/adenovirus E1B 19kDa interacting protein 3
multiple interactions
ISO
10
133,781,204
133,795,435
RGD:6480464
CTD
G
BTBD11
BTB (POZ) domain containing 11
multiple interactions
EXP
12
107,712,197
108,053,419
RGD:6480464
CTD
G
BTC
betacellulin
multiple interactions
ISO
4
75,671,448
75,719,882
RGD:6480464
CTD
G
BTK
Bruton agammaglobulinemia tyrosine kinase
multiple interactions
ISO
X
100,604,435
100,641,212
RGD:6480464
CTD
G
BUB1
BUB1 mitotic checkpoint serine/threonine kinase
multiple interactions
EXP
2
111,395,409
111,435,684
RGD:6480464
CTD
G
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B
multiple interactions
EXP
15
40,453,210
40,513,337
RGD:6480464
CTD
G
C1QA
complement component 1, q subcomponent, A chain
decreases expression
ISO
1
22,963,118
22,966,175
RGD:6480464
CTD
G
C1QC
complement component 1, q subcomponent, C chain
decreases expression
ISO
1
22,970,118
22,974,603
RGD:6480464
CTD
G
C3
complement component 3
decreases expression
ISO
19
6,677,846
6,720,662
RGD:6480464
CTD
G
C7orf41
chromosome 7 open reading frame 41
multiple interactions
EXP
7
30,174,552
30,202,381
RGD:6480464
CTD
G
C9orf3
chromosome 9 open reading frame 3
multiple interactions
EXP
9
97,488,951
97,849,500
RGD:6480464
CTD
G
CALD1
caldesmon 1
multiple interactions
EXP
7
134,464,164
134,655,480
RGD:6480464
CTD
G
CALD1
caldesmon 1
increases expression
EXP
7
134,464,164
134,655,480
RGD:6480464
CTD
G
CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
multiple interactions
ISO
5
149,599,054
149,669,403
RGD:6480464
CTD
G
CAPN1
calpain 1, (mu/I) large subunit
decreases activity
ISO
11
64,948,686
64,979,477
RGD:6480464
CTD
G
CASP12
caspase 12 (gene/pseudogene)
decreases cleavage
ISO
11
104,756,445
104,769,397
RGD:6480464
CTD
G
CASP2
caspase 2, apoptosis-related cysteine peptidase
multiple interactions
EXP
7
142,985,308
143,004,789
RGD:6480464
CTD
G
CASP3
caspase 3, apoptosis-related cysteine peptidase
multiple interactions
EXP
4
185,548,850
185,570,629
RGD:6480464
CTD
G
CASP3
caspase 3, apoptosis-related cysteine peptidase
multiple interactions
EXP
4
185,548,850
185,570,629
RGD:6480464
CTD
G
CASP3
caspase 3, apoptosis-related cysteine peptidase
multiple interactions
EXP
4
185,548,850
185,570,629
RGD:6480464
CTD
G
CASP3
caspase 3, apoptosis-related cysteine peptidase
multiple interactions
EXP
4
185,548,850
185,570,629
RGD:6480464
CTD
G
CASP3
caspase 3, apoptosis-related cysteine peptidase
multiple interactions
EXP
4
185,548,850
185,570,629
RGD:6480464
CTD
G
CASP3
caspase 3, apoptosis-related cysteine peptidase
multiple interactions
EXP
4
185,548,850
185,570,629
RGD:6480464
CTD
G
CASP3
caspase 3, apoptosis-related cysteine peptidase
multiple interactions
EXP
4
185,548,850
185,570,629
RGD:6480464
CTD
G
CASP3
caspase 3, apoptosis-related cysteine peptidase
increases activity
EXP
4
185,548,850
185,570,629
RGD:6480464
CTD
G
CASP3
caspase 3, apoptosis-related cysteine peptidase
increases cleavage
EXP
4
185,548,850
185,570,629
RGD:6480464
CTD
G
CASP3
caspase 3, apoptosis-related cysteine peptidase
increases expression
EXP
4
185,548,850
185,570,629
RGD:6480464
CTD
G
CASP3
caspase 3, apoptosis-related cysteine peptidase
decreases activity
ISO
4
185,548,850
185,570,629
RGD:6480464
CTD
G
CASP3
caspase 3, apoptosis-related cysteine peptidase
increases activity
ISO
4
185,548,850
185,570,629
RGD:6480464
CTD
G
CASP3
caspase 3, apoptosis-related cysteine peptidase
increases expression
ISO
4
185,548,850
185,570,629
RGD:6480464
CTD
G
CASP3
caspase 3, apoptosis-related cysteine peptidase
multiple interactions
ISO
4
185,548,850
185,570,629
RGD:6480464
CTD
G
CASP3
caspase 3, apoptosis-related cysteine peptidase
increases expression
ISO
4
185,548,850
185,570,629
RGD:6480464
CTD
G
CASP3
caspase 3, apoptosis-related cysteine peptidase
decreases activity
ISO
4
185,548,850
185,570,629
RGD:6480464
CTD
G
CASP3
caspase 3, apoptosis-related cysteine peptidase
multiple interactions
ISO
4
185,548,850
185,570,629
RGD:6480464
CTD
G
CASP3
caspase 3, apoptosis-related cysteine peptidase
multiple interactions
EXP
4
185,548,850
185,570,629
RGD:6480464
CTD
G
CASP7
caspase 7, apoptosis-related cysteine peptidase
multiple interactions
EXP
10
115,438,921
115,490,668
RGD:6480464
CTD
G
CASP7
caspase 7, apoptosis-related cysteine peptidase
multiple interactions
EXP
10
115,438,921
115,490,668
RGD:6480464
CTD
G
CASP7
caspase 7, apoptosis-related cysteine peptidase
decreases activity
ISO
10
115,438,921
115,490,668
RGD:6480464
CTD
G
CASP8
caspase 8, apoptosis-related cysteine peptidase
multiple interactions
EXP
2
202,098,166
202,152,434
RGD:6480464
CTD
G
CASP8
caspase 8, apoptosis-related cysteine peptidase
multiple interactions
EXP
2
202,098,166
202,152,434
RGD:6480464
CTD
G
CASP8
caspase 8, apoptosis-related cysteine peptidase
multiple interactions
EXP
2
202,098,166
202,152,434
RGD:6480464
CTD
G
CASP9
caspase 9, apoptosis-related cysteine peptidase
multiple interactions
EXP
1
15,818,769
15,851,285
RGD:6480464
CTD
G
CASP9
caspase 9, apoptosis-related cysteine peptidase
multiple interactions
EXP
1
15,818,769
15,851,285
RGD:6480464
CTD
G
CASP9
caspase 9, apoptosis-related cysteine peptidase
multiple interactions
EXP
1
15,818,769
15,851,285
RGD:6480464
CTD
G
CASP9
caspase 9, apoptosis-related cysteine peptidase
multiple interactions
EXP
1
15,818,769
15,851,285
RGD:6480464
CTD
G
CASP9
caspase 9, apoptosis-related cysteine peptidase
multiple interactions
EXP
1
15,818,769
15,851,285
RGD:6480464
CTD
G
CASP9
caspase 9, apoptosis-related cysteine peptidase
multiple interactions
EXP
1
15,818,769
15,851,285
RGD:6480464
CTD
G
CASP9
caspase 9, apoptosis-related cysteine peptidase
decreases activity
ISO
1
15,818,769
15,851,285
RGD:6480464
CTD
G
CASP9
caspase 9, apoptosis-related cysteine peptidase
multiple interactions
ISO
1
15,818,769
15,851,285
RGD:6480464
CTD
G
CAV3
caveolin 3
multiple interactions
EXP
3
8,775,486
8,788,451
RGD:6480464
CTD
G
CCNA2
cyclin A2
multiple interactions
EXP
4
122,737,599
122,745,088
RGD:6480464
CTD
G
CCNA2
cyclin A2
decreases expression
EXP
4
122,737,599
122,745,088
RGD:6480464
CTD
G
CCNA2
cyclin A2
decreases expression
ISO
4
122,737,599
122,745,088
RGD:6480464
CTD
G
CCNA2
cyclin A2
decreases expression
EXP
4
122,737,599
122,745,088
RGD:6480464
CTD
G
CCNB2
cyclin B2
multiple interactions
EXP
15
59,397,284
59,417,244
RGD:6480464
CTD
G
CCND1
cyclin D1
multiple interactions
EXP
11
69,455,873
69,469,242
RGD:6480464
CTD
G
CCND1
cyclin D1
multiple interactions
EXP
11
69,455,873
69,469,242
RGD:6480464
CTD
G
CCND1
cyclin D1
multiple interactions
EXP
11
69,455,873
69,469,242
RGD:6480464
CTD
G
CCND1
cyclin D1
multiple interactions
EXP
11
69,455,873
69,469,242
RGD:6480464
CTD
G
CCND1
cyclin D1
multiple interactions
EXP
11
69,455,873
69,469,242
RGD:6480464
CTD
G
CCND1
cyclin D1
decreases expression
EXP
11
69,455,873
69,469,242
RGD:6480464
CTD
G
CCND1
cyclin D1
increases degradation
EXP
11
69,455,873
69,469,242
RGD:6480464
CTD
G
CCND1
cyclin D1
increases expression
EXP
11
69,455,873
69,469,242
RGD:6480464
CTD
G
CCND1
cyclin D1
multiple interactions
ISO
11
69,455,873
69,469,242
RGD:6480464
CTD
G
CCND1
cyclin D1
decreases expression
ISO
11
69,455,873
69,469,242
RGD:6480464
CTD
G
CCND1
cyclin D1
decreases expression
EXP
11
69,455,873
69,469,242
RGD:6480464
CTD
G
CCND1
cyclin D1
decreases expression
EXP
11
69,455,873
69,469,242
RGD:6480464
CTD
G
CCND1
cyclin D1
multiple interactions
EXP
11
69,455,873
69,469,242
RGD:6480464
CTD
G
CCND2
cyclin D2
multiple interactions
EXP
12
4,382,902
4,414,522
RGD:6480464
CTD
G
CCND2
cyclin D2
multiple interactions
ISO
12
4,382,902
4,414,522
RGD:6480464
CTD
G
CCND2
cyclin D2
decreases expression
EXP
12
4,382,902
4,414,522
RGD:6480464
CTD
G
CCND3
cyclin D3
multiple interactions
EXP
6
41,902,671
42,016,610
RGD:6480464
CTD
G
CCND3
cyclin D3
decreases expression
EXP
6
41,902,671
42,016,610
RGD:6480464
CTD
G
CCND3
cyclin D3
decreases expression
EXP
6
41,902,671
42,016,610
RGD:6480464
CTD
G
CCND3
cyclin D3
decreases stability
EXP
6
41,902,671
42,016,610
RGD:6480464
CTD
G
CCND3
cyclin D3
multiple interactions
ISO
6
41,902,671
42,016,610
RGD:6480464
CTD
G
CCND3
cyclin D3
decreases expression
EXP
6
41,902,671
42,016,610
RGD:6480464
CTD
G
CCND3
cyclin D3
decreases expression
EXP
6
41,902,671
42,016,610
RGD:6480464
CTD
G
CCND3
cyclin D3
decreases expression
EXP
6
41,902,671
42,016,610
RGD:6480464
CTD
G
CCNE2
cyclin E2
multiple interactions
EXP
8
95,892,452
95,907,482
RGD:6480464
CTD
G
CCNG2
cyclin G2
multiple interactions
EXP
4
78,078,357
78,091,213
RGD:6480464
CTD
G
CCNG2
cyclin G2
multiple interactions
EXP
4
78,078,357
78,091,213
RGD:6480464
CTD
G
CCNI
cyclin I
multiple interactions
ISO
4
77,969,165
77,997,125
RGD:6480464
CTD
G
CD36
CD36 molecule (thrombospondin receptor)
affects expression
EXP
7
80,231,504
80,308,593
RGD:6480464
CTD
G
CD36
CD36 molecule (thrombospondin receptor)
multiple interactions
EXP
7
80,231,504
80,308,593
RGD:6480464
CTD
G
CD68
CD68 molecule
decreases expression
EXP
17
7,482,805
7,485,429
RGD:6480464
CTD
G
CD68
CD68 molecule
decreases expression
ISO
17
7,482,805
7,485,429
RGD:6480464
CTD
G
CD80
CD80 molecule
decreases expression
ISO
3
119,243,140
119,278,481
RGD:6480464
CTD
G
CD86
CD86 molecule
decreases expression
ISO
3
121,774,209
121,839,990
RGD:6480464
CTD
G
CDC20
cell division cycle 20
multiple interactions
EXP
1
43,824,626
43,828,874
RGD:6480464
CTD
G
CDK1
cyclin-dependent kinase 1
multiple interactions
EXP
10
62,538,089
62,554,610
RGD:6480464
CTD
G
CDK1
cyclin-dependent kinase 1
multiple interactions
EXP
10
62,538,089
62,554,610
RGD:6480464
CTD
G
CDK1
cyclin-dependent kinase 1
multiple interactions
EXP
10
62,538,089
62,554,610
RGD:6480464
CTD
G
CDK1
cyclin-dependent kinase 1
multiple interactions
EXP
10
62,538,089
62,554,610
RGD:6480464
CTD
G
CDK1
cyclin-dependent kinase 1
decreases expression
EXP
10
62,538,089
62,554,610
RGD:6480464
CTD
G
CDK1
cyclin-dependent kinase 1
multiple interactions
ISO
10
62,538,089
62,554,610
RGD:6480464
CTD
G
CDK1
cyclin-dependent kinase 1
decreases activity
ISO
10
62,538,089
62,554,610
RGD:6480464
CTD
G
CDK1
cyclin-dependent kinase 1
decreases expression
ISO
10
62,538,089
62,554,610
RGD:6480464
CTD
G
CDK1
cyclin-dependent kinase 1
decreases activity
ISO
10
62,538,089
62,554,610
RGD:6480464
CTD
G
CDK1
cyclin-dependent kinase 1
multiple interactions
EXP
10
62,538,089
62,554,610
RGD:6480464
CTD
G
CDK2
cyclin-dependent kinase 2
multiple interactions
EXP
12
56,360,556
56,366,568
RGD:6480464
CTD
G
CDK2
cyclin-dependent kinase 2
decreases activity
EXP
12
56,360,556
56,366,568
RGD:6480464
CTD
G
CDK2
cyclin-dependent kinase 2
multiple interactions
EXP
12
56,360,556
56,366,568
RGD:6480464
CTD
G
CDK2
cyclin-dependent kinase 2
multiple interactions
ISO
12
56,360,556
56,366,568
RGD:6480464
CTD
G
CDK2
cyclin-dependent kinase 2
multiple interactions
ISO
12
56,360,556
56,366,568
RGD:6480464
CTD
G
CDK2
cyclin-dependent kinase 2
decreases activity
ISO
12
56,360,556
56,366,568
RGD:6480464
CTD
G
CDK2
cyclin-dependent kinase 2
decreases activity
EXP
12
56,360,556
56,366,568
RGD:6480464
CTD
G
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
multiple interactions
EXP
6
36,644,237
36,655,116
RGD:6480464
CTD
G
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
multiple interactions
EXP
6
36,644,237
36,655,116
RGD:6480464
CTD
G
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
increases expression
EXP
6
36,644,237
36,655,116
RGD:6480464
CTD
G
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
multiple interactions
EXP
6
36,644,237
36,655,116
RGD:6480464
CTD
G
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
increases expression
EXP
6
36,644,237
36,655,116
RGD:6480464
CTD
G
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
multiple interactions
EXP
6
36,644,237
36,655,116
RGD:6480464
CTD
G
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
multiple interactions
ISO
6
36,644,237
36,655,116
RGD:6480464
CTD
G
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
increases expression
EXP
6
36,644,237
36,655,116
RGD:6480464
CTD
G
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
multiple interactions
EXP
12
12,870,302
12,875,305
RGD:6480464
CTD
G
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
multiple interactions
EXP
12
12,870,302
12,875,305
RGD:6480464
CTD
G
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
multiple interactions
EXP
12
12,870,302
12,875,305
RGD:6480464
CTD
G
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
decreases degradation
EXP
12
12,870,302
12,875,305
RGD:6480464
CTD
G
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
increases expression
EXP
12
12,870,302
12,875,305
RGD:6480464
CTD
G
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
multiple interactions
EXP
12
12,870,302
12,875,305
RGD:6480464
CTD
G
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
multiple interactions
ISO
12
12,870,302
12,875,305
RGD:6480464
CTD
G
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
multiple interactions
ISO
12
12,870,302
12,875,305
RGD:6480464
CTD
G
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
multiple interactions
ISO
12
12,870,302
12,875,305
RGD:6480464
CTD
G
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
increases expression
EXP
12
12,870,302
12,875,305
RGD:6480464
CTD
G
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
increases expression
EXP
12
12,870,302
12,875,305
RGD:6480464
CTD
G
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
increases expression
EXP
12
12,870,302
12,875,305
RGD:6480464
CTD
G
CDX2
caudal type homeobox 2
increases expression
ISO
13
28,536,205
28,543,505
RGD:6480464
CTD
G
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
decreases expression
ISO
19
33,790,840
33,793,430
RGD:6480464
CTD
G
CFD
complement factor D (adipsin)
decreases expression
ISO
19
859,665
863,624
RGD:6480464
CTD
G
CHRNB3
cholinergic receptor, nicotinic, beta 3 (neuronal)
multiple interactions
EXP
8
42,552,562
42,592,209
RGD:6480464
CTD
G
CKS1B
CDC28 protein kinase regulatory subunit 1B
decreases expression
ISO
1
154,947,118
154,951,725
RGD:6480464
CTD
G
CLDN7
claudin 7
increases expression
ISO
17
7,163,222
7,166,512
RGD:6480464
CTD
G
CLEC4A
C-type lectin domain family 4, member A
decreases expression
ISO
12
8,276,228
8,291,203
RGD:6480464
CTD
G
COL1A1
collagen, type I, alpha 1
decreases expression
ISO
17
48,261,457
48,279,000
RGD:6480464
CTD
G
COL1A2
collagen, type I, alpha 2
multiple interactions
EXP
7
94,023,873
94,060,544
RGD:6480464
CTD
G
COL1A2
collagen, type I, alpha 2
multiple interactions
ISO
7
94,023,873
94,060,544
RGD:6480464
CTD
G
CP
ceruloplasmin (ferroxidase)
increases expression
ISO
3
148,880,197
148,939,832
RGD:6480464
CTD
G
CREB1
cAMP responsive element binding protein 1
multiple interactions
ISO
2
208,394,616
208,470,284
RGD:6480464
CTD
G
CSE1L
CSE1 chromosome segregation 1-like (yeast)
decreases expression
ISO
20
47,662,783
47,713,497
RGD:6480464
CTD
G
CSF1
colony stimulating factor 1 (macrophage)
multiple interactions
ISO
1
110,453,233
110,473,616
RGD:6480464
CTD
G
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
multiple interactions
ISO
5
131,409,485
131,411,863
RGD:6480464
CTD
G
CTGF
connective tissue growth factor
increases expression
ISO
6
132,269,316
132,272,518
RGD:6480464
CTD
G
CXCL10
chemokine (C-X-C motif) ligand 10
decreases expression
ISO
4
76,942,269
76,944,689
RGD:6480464
CTD
G
CXCL13
chemokine (C-X-C motif) ligand 13
decreases expression
ISO
4
78,432,907
78,532,988
RGD:6480464
CTD
G
CYBA
cytochrome b-245, alpha polypeptide
multiple interactions
ISO
16
88,709,697
88,717,492
RGD:6480464
CTD
G
CYBB
cytochrome b-245, beta polypeptide
multiple interactions
ISO
X
37,639,270
37,672,714
RGD:6480464
CTD
G
CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
multiple interactions
EXP
2
219,646,472
219,680,016
RGD:6480464
CTD
G
CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
decreases activity
EXP
2
219,646,472
219,680,016
RGD:6480464
CTD
G
CYP3A
cytochrome P450, subfamily IIA (niphedipine oxidase)
affects metabolic processing
EXP
RGD:6480464
CTD
G
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
affects metabolic processing
EXP
7
99,354,583
99,381,811
RGD:6480464
CTD
G
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
affects metabolic processing
EXP
7
99,354,583
99,381,811
RGD:6480464
CTD
G
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
affects metabolic processing
EXP
7
99,354,583
99,381,811
RGD:6480464
CTD
G
DDIT3
DNA-damage-inducible transcript 3
multiple interactions
ISO
12
57,910,371
57,914,300
RGD:6480464
CTD
G
DDIT3
DNA-damage-inducible transcript 3
multiple interactions
ISO
12
57,910,371
57,914,300
RGD:6480464
CTD
G
DDIT3
DNA-damage-inducible transcript 3
multiple interactions
EXP
12
57,910,371
57,914,300
RGD:6480464
CTD
G
DDIT3
DNA-damage-inducible transcript 3
multiple interactions
ISO
12
57,910,371
57,914,300
RGD:6480464
CTD
G
DDIT3
DNA-damage-inducible transcript 3
multiple interactions
EXP
12
57,910,371
57,914,300
RGD:6480464
CTD
G
DDIT4L
DNA-damage-inducible transcript 4-like
decreases expression
ISO
4
101,107,027
101,111,655
RGD:6480464
CTD
G
DDIT4L
DNA-damage-inducible transcript 4-like
increases expression
ISO
4
101,107,027
101,111,655
RGD:6480464
CTD
G
DIABLO
diablo, IAP-binding mitochondrial protein
multiple interactions
EXP
12
122,692,209
122,712,068
RGD:6480464
CTD
G
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
decreases expression
ISO
1
65,730,377
65,881,552
RGD:6480464
CTD
G
DNMT1
DNA (cytosine-5-)-methyltransferase 1
multiple interactions
EXP
19
10,244,022
10,305,755
RGD:6480464
CTD
G
DPYD
dihydropyrimidine dehydrogenase
decreases expression
EXP
1
97,543,299
98,386,615
RGD:6480464
CTD
G
DUSP15
dual specificity phosphatase 15
decreases expression
ISO
20
30,448,870
30,458,479
RGD:6480464
CTD
G
E2F1
E2F transcription factor 1
multiple interactions
EXP
20
32,263,292
32,274,210
RGD:6480464
CTD
G
E2F1
E2F transcription factor 1
multiple interactions
ISO
20
32,263,292
32,274,210
RGD:6480464
CTD
G
E2F4
E2F transcription factor 4, p107/p130-binding
multiple interactions
EXP
16
67,226,068
67,232,821
RGD:6480464
CTD
G
EDN1
endothelin 1
multiple interactions
ISO
6
12,290,529
12,297,427
RGD:6480464
CTD
G
EGF
epidermal growth factor
multiple interactions
EXP
4
110,834,040
110,934,118
RGD:6480464
CTD
G
EGF
epidermal growth factor
decreases activity
ISO
4
110,834,040
110,934,118
RGD:6480464
CTD
G
EGFR
epidermal growth factor receptor
multiple interactions
ISO
7
55,086,725
55,275,031
RGD:6480464
CTD
G
EGFR
epidermal growth factor receptor
multiple interactions
EXP
7
55,086,725
55,275,031
RGD:6480464
CTD
G
EIF4B
eukaryotic translation initiation factor 4B
multiple interactions
ISO
12
53,400,062
53,435,993
RGD:6480464
CTD
G
EIF4E
eukaryotic translation initiation factor 4E
multiple interactions
EXP
4
99,799,607
99,851,786
RGD:6480464
CTD
G
EIF4E
eukaryotic translation initiation factor 4E
decreases activity
EXP
4
99,799,607
99,851,786
RGD:6480464
CTD
G
EIF4E
eukaryotic translation initiation factor 4E
multiple interactions
ISO
4
99,799,607
99,851,786
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
multiple interactions
EXP
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
multiple interactions
EXP
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
multiple interactions
EXP
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
multiple interactions
EXP
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
multiple interactions
EXP
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
multiple interactions
EXP
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
multiple interactions
EXP
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
decreases phosphorylation
EXP
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
multiple interactions
ISO
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
multiple interactions
ISO
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
decreases phosphorylation
ISO
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
multiple interactions
ISO
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
multiple interactions
EXP
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
decreases phosphorylation
EXP
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
decreases phosphorylation
EXP
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
decreases phosphorylation
EXP
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
multiple interactions
ISO
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
multiple interactions
EXP
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
decreases phosphorylation
EXP
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
multiple interactions
ISO
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
decreases phosphorylation
EXP
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
decreases phosphorylation
EXP
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
decreases phosphorylation
ISO
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
multiple interactions
EXP
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
decreases phosphorylation
EXP
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
multiple interactions
EXP
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
increases expression
EXP
11
10,818,593
10,830,582
RGD:6480464
CTD
G
ERO1L
ERO1-like (S. cerevisiae)
multiple interactions
ISO
14
53,108,605
53,162,419
RGD:6480464
CTD
G
ESPL1
extra spindle pole bodies homolog 1 (S. cerevisiae)
multiple interactions
EXP
12
53,662,083
53,687,427
RGD:6480464
CTD
G
ESR1
estrogen receptor 1
increases expression
EXP
6
152,011,631
152,424,409
RGD:6480464
CTD
G
ESR1
estrogen receptor 1
increases phosphorylation
EXP
6
152,011,631
152,424,409
RGD:6480464
CTD
G
EWSR1
Ewing sarcoma breakpoint region 1
decreases expression
EXP
22
29,663,998
29,696,515
RGD:6480464
CTD
G
F2
coagulation factor II (thrombin)
decreases expression
ISO
11
46,740,743
46,761,056
RGD:6480464
CTD
G
F3
coagulation factor III (thromboplastin, tissue factor)
multiple interactions
EXP
1
94,994,732
95,007,413
RGD:6480464
CTD
G
F3
coagulation factor III (thromboplastin, tissue factor)
increases activity
ISO
1
94,994,732
95,007,413
RGD:6480464
CTD
G
FAS
Fas (TNF receptor superfamily, member 6)
decreases expression
ISO
10
90,750,288
90,775,542
RGD:6480464
CTD
G
FASLG
Fas ligand (TNF superfamily, member 6)
decreases secretion
EXP
1
172,628,185
172,636,013
RGD:6480464
CTD
G
FAXDC2
fatty acid hydroxylase domain containing 2
multiple interactions
EXP
5
154,198,052
154,230,213
RGD:6480464
CTD
G
FBLN1
fibulin 1
increases expression
ISO
22
45,898,719
45,997,014
RGD:6480464
CTD
G
FBXO32
F-box protein 32
multiple interactions
EXP
8
124,510,127
124,553,493
RGD:6480464
CTD
G
FBXO5
F-box protein 5
multiple interactions
EXP
6
153,291,658
153,304,740
RGD:6480464
CTD
G
FGB
fibrinogen beta chain
decreases expression
ISO
4
155,484,132
155,493,915
RGD:6480464
CTD
G
FGB
fibrinogen beta chain
increases expression
ISO
4
155,484,132
155,493,915
RGD:6480464
CTD
G
FGF1
fibroblast growth factor 1 (acidic)
multiple interactions
ISO
5
141,971,743
142,077,635
RGD:6480464
CTD
G
FGF7
fibroblast growth factor 7
multiple interactions
EXP
15
49,715,375
49,779,523
RGD:6480464
CTD
G
FKBP1A
FK506 binding protein 1A, 12kDa
affects binding
EXP
20
1,349,621
1,373,816
RGD:6480464
CTD
G
FKBP1A
FK506 binding protein 1A, 12kDa
multiple interactions
EXP
20
1,349,621
1,373,816
RGD:6480464
CTD
G
FKBP1A
FK506 binding protein 1A, 12kDa
multiple interactions
EXP
20
1,349,621
1,373,816
RGD:6480464
CTD
G
FKBP1A
FK506 binding protein 1A, 12kDa
multiple interactions
ISO
20
1,349,621
1,373,816
RGD:6480464
CTD
G
FKBP1A
FK506 binding protein 1A, 12kDa
affects binding
ISO
20
1,349,621
1,373,816
RGD:6480464
CTD
G
FKBP1A
FK506 binding protein 1A, 12kDa
multiple interactions
ISO
20
1,349,621
1,373,816
RGD:6480464
CTD
G
FKBP1A
FK506 binding protein 1A, 12kDa
multiple interactions
ISO
20
1,349,621
1,373,816
RGD:6480464
CTD
G
FKBP1A
FK506 binding protein 1A, 12kDa
affects binding
ISO
20
1,349,621
1,373,816
RGD:6480464
CTD
G
FKBP1A
FK506 binding protein 1A, 12kDa
affects binding
ISO
20
1,349,621
1,373,816
RGD:6480464
CTD
G
FLT3LG
fms-related tyrosine kinase 3 ligand
decreases activity
ISO
19
49,977,466
49,989,488
RGD:6480464
CTD
G
FOLR1
folate receptor 1 (adult)
multiple interactions
EXP
11
71,900,602
71,907,367
RGD:6480464
CTD
G
FOXM1
forkhead box M1
multiple interactions
EXP
12
2,966,847
2,986,321
RGD:6480464
CTD
G
FOXO1
forkhead box O1
increases phosphorylation
EXP
13
41,129,801
41,240,734
RGD:6480464
CTD
G
FOXP3
forkhead box P3
multiple interactions
EXP
X
49,106,897
49,121,288
RGD:6480464
CTD
G
FOXP3
forkhead box P3
increases expression
ISO
X
49,106,897
49,121,288
RGD:6480464
CTD
G
FSHB
follicle stimulating hormone, beta polypeptide
multiple interactions
ISO
11
30,252,563
30,256,824
RGD:6480464
CTD
G
FTL
ferritin, light polypeptide
multiple interactions
EXP
19
49,468,566
49,470,136
RGD:6480464
CTD
G
GABARAP
GABA(A) receptor-associated protein
increases expression
ISO
17
7,143,738
7,145,753
RGD:6480464
CTD
G
GABARAPL1
GABA(A) receptor-associated protein like 1
multiple interactions
ISO
12
10,365,489
10,375,727
RGD:6480464
CTD
G
GCM2
glial cells missing homolog 2 (Drosophila)
multiple interactions
EXP
6
10,873,456
10,882,098
RGD:6480464
CTD
G
GGT1
gamma-glutamyltransferase 1
multiple interactions
ISO
22
24,979,718
25,024,972
RGD:6480464
CTD
G
GPNMB
glycoprotein (transmembrane) nmb
increases expression
ISO
7
23,286,316
23,314,729
RGD:6480464
CTD
G
GPT
glutamic-pyruvate transaminase (alanine aminotransferase)
multiple interactions
ISO
8
145,729,465
145,732,555
RGD:6480464
CTD
G
GSK3B
glycogen synthase kinase 3 beta
multiple interactions
EXP
3
119,540,800
119,813,264
RGD:6480464
CTD
G
GSK3B
glycogen synthase kinase 3 beta
multiple interactions
EXP
3
119,540,800
119,813,264
RGD:6480464
CTD
G
GSK3B
glycogen synthase kinase 3 beta
increases activity
EXP
3
119,540,800
119,813,264
RGD:6480464
CTD
G
GSK3B
glycogen synthase kinase 3 beta
multiple interactions
ISO
3
119,540,800
119,813,264
RGD:6480464
CTD
G
GSTT1
glutathione S-transferase theta 1
increases response to substance
EXP
22
24,376,139
24,384,284
RGD:6480464
CTD
G
GTPBP4
GTP binding protein 4
decreases expression
ISO
10
1,034,349
1,063,708
RGD:6480464
CTD
G
GUCA2A
guanylate cyclase activator 2A (guanylin)
increases expression
ISO
1
42,628,362
42,630,395
RGD:6480464
CTD
G
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
decreases expression
EXP
14
25,100,160
25,103,432
RGD:6480464
CTD
G
HAVCR1
hepatitis A virus cellular receptor 1
increases expression
ISO
5
156,456,531
156,485,970
RGD:6480464
CTD
G
HES1
hairy and enhancer of split 1, (Drosophila)
decreases expression
EXP
3
193,853,931
193,856,401
RGD:6480464
CTD
G
HES1
hairy and enhancer of split 1, (Drosophila)
decreases expression
ISO
3
193,853,931
193,856,401
RGD:6480464
CTD
G
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
multiple interactions
EXP
14
62,162,119
62,214,977
RGD:6480464
CTD
G
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
multiple interactions
EXP
14
62,162,119
62,214,977
RGD:6480464
CTD
G
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
multiple interactions
EXP
14
62,162,119
62,214,977
RGD:6480464
CTD
G
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
decreases expression
EXP
14
62,162,119
62,214,977
RGD:6480464
CTD
G
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
decreases expression
ISO
14
62,162,119
62,214,977
RGD:6480464
CTD
G
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
multiple interactions
EXP
14
62,162,119
62,214,977
RGD:6480464
CTD
G
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
multiple interactions
EXP
14
62,162,119
62,214,977
RGD:6480464
CTD
G
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
multiple interactions
EXP
14
62,162,119
62,214,977
RGD:6480464
CTD
G
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
multiple interactions
EXP
14
62,162,119
62,214,977
RGD:6480464
CTD
G
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
increases expression
EXP
5
74,632,993
74,657,926
RGD:6480464
CTD
G
HMOX1
heme oxygenase (decycling) 1
increases expression
ISO
22
35,777,060
35,790,207
RGD:6480464
CTD
G
HMOX1
heme oxygenase (decycling) 1
multiple interactions
ISO
22
35,777,060
35,790,207
RGD:6480464
CTD
G
HOXA9
homeobox A9
multiple interactions
EXP
7
27,202,057
27,205,149
RGD:6480464
CTD
G
HSPB8
heat shock 22kDa protein 8
decreases expression
EXP
12
119,616,595
119,632,551
RGD:6480464
CTD
G
ICAM1
intercellular adhesion molecule 1
decreases expression
ISO
19
10,381,517
10,397,291
RGD:6480464
CTD
G
IFNG
interferon, gamma
multiple interactions
EXP
12
68,548,550
68,553,521
RGD:6480464
CTD
G
IFNG
interferon, gamma
decreases secretion
EXP
12
68,548,550
68,553,521
RGD:6480464
CTD
G
IFNG
interferon, gamma
multiple interactions
ISO
12
68,548,550
68,553,521
RGD:6480464
CTD
G
IGF1
insulin-like growth factor 1 (somatomedin C)
multiple interactions
EXP
12
102,789,645
102,874,378
RGD:6480464
CTD
G
IGF1
insulin-like growth factor 1 (somatomedin C)
multiple interactions
EXP
12
102,789,645
102,874,378
RGD:6480464
CTD
G
IGF1
insulin-like growth factor 1 (somatomedin C)
multiple interactions
EXP
12
102,789,645
102,874,378
RGD:6480464
CTD
G
IGF1
insulin-like growth factor 1 (somatomedin C)
multiple interactions
ISO
12
102,789,645
102,874,378
RGD:6480464
CTD
G
IGF1
insulin-like growth factor 1 (somatomedin C)
increases response to substance
EXP
12
102,789,645
102,874,378
RGD:6480464
CTD
G
IGF1
insulin-like growth factor 1 (somatomedin C)
multiple interactions
ISO
12
102,789,645
102,874,378
RGD:6480464
CTD
G
IGF1
insulin-like growth factor 1 (somatomedin C)
multiple interactions
EXP
12
102,789,645
102,874,378
RGD:6480464
CTD
G
IGF1
insulin-like growth factor 1 (somatomedin C)
multiple interactions
EXP
12
102,789,645
102,874,378
RGD:6480464
CTD
G
IGF1R
insulin-like growth factor 1 receptor
affects activity
EXP
15
99,192,761
99,507,759
RGD:6480464
CTD
G
IGF1R
insulin-like growth factor 1 receptor
multiple interactions
EXP
15
99,192,761
99,507,759
RGD:6480464
CTD
G
IGFBP1
insulin-like growth factor binding protein 1
increases expression
ISO
7
45,927,959
45,933,267
RGD:6480464
CTD
G
IGFBP3
insulin-like growth factor binding protein 3
multiple interactions
EXP
7
45,951,844
45,960,871
RGD:6480464
CTD
G
IGFBP5
insulin-like growth factor binding protein 5
decreases expression
ISO
2
217,536,828
217,560,272
RGD:6480464
CTD
G
IL10
interleukin 10
multiple interactions
EXP
1
206,940,948
206,945,839
RGD:6480464
CTD
G
IL10
interleukin 10
multiple interactions
ISO
1
206,940,948
206,945,839
RGD:6480464
CTD
G
IL10
interleukin 10
decreases expression
ISO
1
206,940,948
206,945,839
RGD:6480464
CTD
G
IL10
interleukin 10
decreases expression
EXP
1
206,940,948
206,945,839
RGD:6480464
CTD
G
IL12A
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
multiple interactions
ISO
3
159,706,623
159,713,806
RGD:6480464
CTD
G
IL12B
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
multiple interactions
ISO
5
158,741,791
158,757,481
RGD:6480464
CTD
G
IL17RB
interleukin 17 receptor B
multiple interactions
EXP
3
53,880,577
53,899,827
RGD:6480464
CTD
G
IL1B
interleukin 1, beta
multiple interactions
ISO
2
113,587,337
113,594,356
RGD:6480464
CTD
G
IL2
interleukin 2
multiple interactions
EXP
4
123,372,625
123,377,650
RGD:6480464
CTD
G
IL2
interleukin 2
multiple interactions
EXP
4
123,372,625
123,377,650
RGD:6480464
CTD
G
IL2
interleukin 2
decreases response to substance
EXP
4
123,372,625
123,377,650
RGD:6480464
CTD
G
IL2
interleukin 2
multiple interactions
ISO
4
123,372,625
123,377,650
RGD:6480464
CTD
G
IL2
interleukin 2
multiple interactions
ISO
4
123,372,625
123,377,650
RGD:6480464
CTD
G
IL2
interleukin 2
multiple interactions
ISO
4
123,372,625
123,377,650
RGD:6480464
CTD
G
IL2RA
interleukin 2 receptor, alpha
multiple interactions
EXP
10
6,052,657
6,104,333
RGD:6480464
CTD
G
IL2RG
interleukin 2 receptor, gamma
multiple interactions
ISO
X
70,327,254
70,331,481
RGD:6480464
CTD
G
IL3
interleukin 3 (colony-stimulating factor, multiple)
multiple interactions
ISO
5
131,396,347
131,398,896
RGD:6480464
CTD
G
IL4
interleukin 4
multiple interactions
ISO
5
132,009,678
132,018,370
RGD:6480464
CTD
G
IL4
interleukin 4
decreases expression
ISO
5
132,009,678
132,018,370
RGD:6480464
CTD
G
IL4
interleukin 4
multiple interactions
ISO
5
132,009,678
132,018,370
RGD:6480464
CTD
G
IL4
interleukin 4
decreases expression
ISO
5
132,009,678
132,018,370
RGD:6480464
CTD
G
IL4R
interleukin 4 receptor
multiple interactions
ISO
16
27,325,230
27,376,099
RGD:6480464
CTD
G
IL5
interleukin 5 (colony-stimulating factor, eosinophil)
decreases expression
ISO
5
131,877,136
131,879,214
RGD:6480464
CTD
G
IL6
interleukin 6 (interferon, beta 2)
multiple interactions
EXP
7
22,766,766
22,771,621
RGD:6480464
CTD
G
IL6
interleukin 6 (interferon, beta 2)
multiple interactions
EXP
7
22,766,766
22,771,621
RGD:6480464
CTD
G
IL6
interleukin 6 (interferon, beta 2)
decreases expression
ISO
7
22,766,766
22,771,621
RGD:6480464
CTD
G
IL6
interleukin 6 (interferon, beta 2)
increases expression
EXP
7
22,766,766
22,771,621
RGD:6480464
CTD
G
IL8
interleukin 8
multiple interactions
EXP
4
74,606,223
74,609,433
RGD:6480464
CTD
G
ING4
inhibitor of growth family, member 4
multiple interactions
EXP
12
6,759,704
6,772,308
RGD:6480464
CTD
G
IRS1
insulin receptor substrate 1
affects phosphorylation
EXP
2
227,596,033
227,663,506
RGD:6480464
CTD
G
IRS1
insulin receptor substrate 1
multiple interactions
EXP
2
227,596,033
227,663,506
RGD:6480464
CTD
G
IRS1
insulin receptor substrate 1
multiple interactions
EXP
2
227,596,033
227,663,506
RGD:6480464
CTD
G
IRS1
insulin receptor substrate 1
decreases degradation
EXP
2
227,596,033
227,663,506
RGD:6480464
CTD
G
IRS1
insulin receptor substrate 1
decreases phosphorylation
EXP
2
227,596,033
227,663,506
RGD:6480464
CTD
G
IRS1
insulin receptor substrate 1
decreases degradation
EXP
2
227,596,033
227,663,506
RGD:6480464
CTD
G
ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
multiple interactions
EXP
16
31,271,288
31,344,213
RGD:6480464
CTD
G
ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
increases expression
EXP
16
31,271,288
31,344,213
RGD:6480464
CTD
G
ITGAV
integrin, alpha V
decreases expression
ISO
2
187,454,790
187,545,628
RGD:6480464
CTD
G
JAG1
jagged 1
decreases expression
EXP
20
10,618,332
10,654,694
RGD:6480464
CTD
G
JAG1
jagged 1
decreases expression
ISO
20
10,618,332
10,654,694
RGD:6480464
CTD
G
JMY
junction mediating and regulatory protein, p53 cofactor
multiple interactions
EXP
5
78,531,925
78,623,038
RGD:6480464
CTD
G
KIFAP3
kinesin-associated protein 3
increases expression
ISO
1
169,890,470
170,043,879
RGD:6480464
CTD
G
KIFC1
kinesin family member C1
decreases expression
ISO
6
33,359,313
33,377,701
RGD:6480464
CTD
G
KIFC1
kinesin family member C1
decreases expression
ISO
6
33,359,313
33,377,701
RGD:6480464
CTD
G
KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
multiple interactions
EXP
4
55,524,095
55,606,881
RGD:6480464
CTD
G
KITLG
KIT ligand
multiple interactions
ISO
12
88,886,570
88,974,250
RGD:6480464
CTD
G
KLF5
Kruppel-like factor 5 (intestinal)
increases expression
ISO
13
73,633,142
73,651,676
RGD:6480464
CTD
G
KLF6
Kruppel-like factor 6
decreases phosphorylation
ISO
10
3,818,188
3,827,473
RGD:6480464
CTD
G
KLK2
kallikrein-related peptidase 2
multiple interactions
EXP
19
51,376,689
51,383,823
RGD:6480464
CTD
G
KLK3
kallikrein-related peptidase 3
increases expression
EXP
19
51,358,171
51,364,020
RGD:6480464
CTD
G
KLK3
kallikrein-related peptidase 3
multiple interactions
EXP
19
51,358,171
51,364,020
RGD:6480464
CTD
G
L1CAM
L1 cell adhesion molecule
affects response to substance
EXP
X
153,126,971
153,141,399
RGD:6480464
CTD
G
LAMC2
laminin, gamma 2
increases expression
ISO
1
183,155,174
183,214,262
RGD:6480464
CTD
G
LCN2
lipocalin 2
increases expression
ISO
9
130,911,732
130,915,734
RGD:6480464
CTD
G
LIPE
lipase, hormone-sensitive
multiple interactions
ISO
19
42,905,666
42,931,578
RGD:6480464
CTD
G
MAD2L1
MAD2 mitotic arrest deficient-like 1 (yeast)
multiple interactions
EXP
4
120,980,577
120,988,013
RGD:6480464
CTD
G
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
multiple interactions
EXP
20
33,134,688
33,148,149
RGD:6480464
CTD
G
MAP1LC3B
microtubule-associated protein 1 light chain 3 beta
increases expression
EXP
16
87,425,801
87,438,380
RGD:6480464
CTD
G
MAP1LC3B
microtubule-associated protein 1 light chain 3 beta
increases expression
EXP
16
87,425,801
87,438,380
RGD:6480464
CTD
G
MAP1LC3B
microtubule-associated protein 1 light chain 3 beta
increases expression
ISO
16
87,425,801
87,438,380
RGD:6480464
CTD
G
MAP1LC3B
microtubule-associated protein 1 light chain 3 beta
affects localization
ISO
16
87,425,801
87,438,380
RGD:6480464
CTD
G
MAP1LC3B
microtubule-associated protein 1 light chain 3 beta
multiple interactions
ISO
16
87,425,801
87,438,380
RGD:6480464
CTD
G
MAP1LC3B
microtubule-associated protein 1 light chain 3 beta
increases expression
ISO
16
87,425,801
87,438,380
RGD:6480464
CTD
G
MAP2K1
mitogen-activated protein kinase kinase 1
multiple interactions
EXP
15
66,679,211
66,783,882
RGD:6480464
CTD
G
MAP2K1
mitogen-activated protein kinase kinase 1
multiple interactions
ISO
15
66,679,211
66,783,882
RGD:6480464
CTD
G
MAP2K2
mitogen-activated protein kinase kinase 2
multiple interactions
EXP
19
4,090,319
4,124,126
RGD:6480464
CTD
G
MAPK1
mitogen-activated protein kinase 1
multiple interactions
EXP
22
22,113,946
22,221,970
RGD:6480464
CTD
G
MAPK1
mitogen-activated protein kinase 1
multiple interactions
EXP
22
22,113,946
22,221,970
RGD:6480464
CTD
G
MAPK1
mitogen-activated protein kinase 1
decreases phosphorylation
EXP
22
22,113,946
22,221,970
RGD:6480464
CTD
G
MAPK1
mitogen-activated protein kinase 1
increases phosphorylation
EXP
22
22,113,946
22,221,970
RGD:6480464
CTD
G
MAPK1
mitogen-activated protein kinase 1
multiple interactions
ISO
22
22,113,946
22,221,970
RGD:6480464
CTD
G
MAPK1
mitogen-activated protein kinase 1
increases phosphorylation
ISO
22
22,113,946
22,221,970
RGD:6480464
CTD
G
MAPK1
mitogen-activated protein kinase 1
increases phosphorylation
ISO
22
22,113,946
22,221,970
RGD:6480464
CTD
G
MAPK1
mitogen-activated protein kinase 1
increases phosphorylation
ISO
22
22,113,946
22,221,970
RGD:6480464
CTD
G
MAPK1
mitogen-activated protein kinase 1
multiple interactions
EXP
22
22,113,946
22,221,970
RGD:6480464
CTD
G
MAPK1
mitogen-activated protein kinase 1
multiple interactions
ISO
22
22,113,946
22,221,970
RGD:6480464
CTD
G
MAPK3
mitogen-activated protein kinase 3
multiple interactions
EXP
16
30,125,426
30,134,630
RGD:6480464
CTD
G
MAPK3
mitogen-activated protein kinase 3
multiple interactions
EXP
16
30,125,426
30,134,630
RGD:6480464
CTD
G
MAPK3
mitogen-activated protein kinase 3
decreases phosphorylation
EXP
16
30,125,426
30,134,630
RGD:6480464
CTD
G
MAPK3
mitogen-activated protein kinase 3
increases phosphorylation
EXP
16
30,125,426
30,134,630
RGD:6480464
CTD
G
MAPK3
mitogen-activated protein kinase 3
multiple interactions
ISO
16
30,125,426
30,134,630
RGD:6480464
CTD
G
MAPK3
mitogen-activated protein kinase 3
increases phosphorylation
ISO
16
30,125,426
30,134,630
RGD:6480464
CTD
G
MAPK3
mitogen-activated protein kinase 3
decreases phosphorylation
ISO
16
30,125,426
30,134,630
RGD:6480464
CTD
G
MAPK3
mitogen-activated protein kinase 3
increases phosphorylation
ISO
16
30,125,426
30,134,630
RGD:6480464
CTD
G
MAPK3
mitogen-activated protein kinase 3
increases phosphorylation
ISO
16
30,125,426
30,134,630
RGD:6480464
CTD
G
MAPK3
mitogen-activated protein kinase 3
multiple interactions
EXP
16
30,125,426
30,134,630
RGD:6480464
CTD
G
MAPK3
mitogen-activated protein kinase 3
multiple interactions
ISO
16
30,125,426
30,134,630
RGD:6480464
CTD
G
MAPK8
mitogen-activated protein kinase 8
multiple interactions
EXP
10
49,609,687
49,643,183
RGD:6480464
CTD
G
MBNL2
muscleblind-like splicing regulator 2
multiple interactions
EXP
13
97,874,550
98,046,374
RGD:6480464
CTD
G
MBP
myelin basic protein
increases expression
ISO
18
74,690,789
74,844,774
RGD:6480464
CTD
G
MCL1
myeloid cell leukemia sequence 1 (BCL2-related)
multiple interactions
EXP
1
150,547,027
150,552,214
RGD:6480464
CTD
G
MCM2
minichromosome maintenance complex component 2
multiple interactions
ISO
3
127,317,253
127,341,279
RGD:6480464
CTD
G
MCM7
minichromosome maintenance complex component 7
multiple interactions
ISO
7
99,690,404
99,699,427
RGD:6480464
CTD
G
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
multiple interactions
EXP
12
69,201,971
69,239,320
RGD:6480464
CTD
G
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
multiple interactions
EXP
12
69,201,971
69,239,320
RGD:6480464
CTD
G
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
decreases expression
EXP
12
69,201,971
69,239,320
RGD:6480464
CTD
G
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
multiple interactions
EXP
12
69,201,971
69,239,320
RGD:6480464
CTD
G
MIR181A2
microRNA 181a-2
multiple interactions
EXP
9
127,454,721
127,454,830
RGD:6480464
CTD
G
MIR190A
microRNA 190a
multiple interactions
EXP
15
63,116,156
63,116,240
RGD:6480464
CTD
G
MIR29C
microRNA 29c
multiple interactions
EXP
1
207,975,197
207,975,284
RGD:6480464
CTD
G
MIR324
microRNA 324
multiple interactions
EXP
17
7,126,616
7,126,698
RGD:6480464
CTD
G
MIR379
microRNA 379
multiple interactions
EXP
14
101,488,403
101,488,469
RGD:6480464
CTD
G
MIR433
microRNA 433
multiple interactions
EXP
14
101,348,223
101,348,315
RGD:6480464
CTD
G
MIR503
microRNA 503
multiple interactions
EXP
X
133,680,358
133,680,428
RGD:6480464
CTD
G
MIR508
microRNA 508
multiple interactions
EXP
X
146,318,431
146,318,545
RGD:6480464
CTD
G
MIR650
microRNA 650
multiple interactions
EXP
22
23,165,270
23,165,365
RGD:6480464
CTD
G
MIR654
microRNA 654
multiple interactions
EXP
14
101,506,556
101,506,636
RGD:6480464
CTD
G
MIR758
microRNA 758
multiple interactions
EXP
14
101,492,357
101,492,444
RGD:6480464
CTD
G
MIR760
microRNA 760
multiple interactions
EXP
1
94,312,388
94,312,467
RGD:6480464
CTD
G
MKI67
antigen identified by monoclonal antibody Ki-67
decreases expression
EXP
10
129,894,923
129,924,468
RGD:6480464
CTD
G
MKI67
antigen identified by monoclonal antibody Ki-67
multiple interactions
EXP
10
129,894,923
129,924,468
RGD:6480464
CTD
G
MLST8
MTOR associated protein, LST8 homolog (S. cerevisiae)
multiple interactions
EXP
16
2,255,178
2,259,418
RGD:6480464
CTD
G
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
increases secretion
EXP
11
102,660,641
102,668,966
RGD:6480464
CTD
G
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
increases expression
EXP
11
102,660,641
102,668,966
RGD:6480464
CTD
G
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
multiple interactions
ISO
16
55,513,081
55,540,586
RGD:6480464
CTD
G
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
decreases expression
ISO
20
44,637,547
44,645,200
RGD:6480464
CTD
G
MPZ
myelin protein zero
increases expression
ISO
1
161,274,525
161,279,762
RGD:6480464
CTD
G
MSR1
macrophage scavenger receptor 1
decreases expression
EXP
8
15,965,387
16,050,300
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases activity
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases activity
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases activity
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases expression
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases phosphorylation
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
increases activity
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases activity
ISO
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
ISO
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases phosphorylation
ISO
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
increases activity
ISO
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases phosphorylation
ISO
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases activity
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases phosphorylation
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases activity
ISO
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases phosphorylation
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases activity
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases phosphorylation
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases activity
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases phosphorylation
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases phosphorylation
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases activity
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases phosphorylation
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases activity
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
ISO
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
ISO
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases activity
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases phosphorylation
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases activity
ISO
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MYBL2
v-myb myeloblastosis viral oncogene homolog (avian)-like 2
multiple interactions
ISO
20
42,295,709
42,345,122
RGD:6480464
CTD
G
MYC
v-myc myelocytomatosis viral oncogene homolog (avian)
multiple interactions
EXP
8
128,748,315
128,753,680
RGD:6480464
CTD
G
MYH11
myosin, heavy chain 11, smooth muscle
multiple interactions
EXP
16
15,796,992
15,950,887
RGD:6480464
CTD
G
MYH11
myosin, heavy chain 11, smooth muscle
increases expression
EXP
16
15,796,992
15,950,887
RGD:6480464
CTD
G
MYLK
myosin light chain kinase
multiple interactions
EXP
3
123,331,143
123,603,149
RGD:6480464
CTD
G
MYOF
myoferlin
multiple interactions
EXP
10
95,066,186
95,242,074
RGD:6480464
CTD
G
NAIP
NLR family, apoptosis inhibitory protein
decreases expression
ISO
5
70,264,310
70,320,941
RGD:6480464
CTD
G
NANOG
Nanog homeobox
increases expression
ISO
12
7,941,995
7,948,655
RGD:6480464
CTD
G
NCF1
neutrophil cytosolic factor 1
multiple interactions
ISO
7
74,188,309
74,203,659
RGD:6480464
CTD
G
NCF1
neutrophil cytosolic factor 1
decreases expression
ISO
7
74,188,309
74,203,659
RGD:6480464
CTD
G
NCF2
neutrophil cytosolic factor 2
decreases expression
ISO
1
183,524,697
183,560,056
RGD:6480464
CTD
G
NCF2
neutrophil cytosolic factor 2
multiple interactions
ISO
1
183,524,697
183,560,056
RGD:6480464
CTD
G
NCF4
neutrophil cytosolic factor 4, 40kDa
multiple interactions
ISO
22
37,257,030
37,274,059
RGD:6480464
CTD
G
NDC80
NDC80 kinetochore complex component
multiple interactions
EXP
18
2,571,510
2,616,634
RGD:6480464
CTD
G
NEK2
NIMA-related kinase 2
multiple interactions
EXP
1
211,831,598
211,848,972
RGD:6480464
CTD
G
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
multiple interactions
EXP
4
103,422,486
103,538,459
RGD:6480464
CTD
G
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
multiple interactions
EXP
14
35,870,716
35,873,960
RGD:6480464
CTD
G
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
multiple interactions
EXP
14
35,870,716
35,873,960
RGD:6480464
CTD
G
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
multiple interactions
ISO
14
35,870,716
35,873,960
RGD:6480464
CTD
G
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
multiple interactions
ISO
14
35,870,716
35,873,960
RGD:6480464
CTD
G
NME1
NME/NM23 nucleoside diphosphate kinase 1
multiple interactions
EXP
17
49,230,920
49,239,450
RGD:6480464
CTD
G
NMU
neuromedin U
multiple interactions
EXP
4
56,461,398
56,502,465
RGD:6480464
CTD
G
NOS2
nitric oxide synthase 2, inducible
multiple interactions
ISO
17
26,083,792
26,127,555
RGD:6480464
CTD
G
NOS3
nitric oxide synthase 3 (endothelial cell)
multiple interactions
EXP
7
150,688,144
150,711,687
RGD:6480464
CTD
G
NOS3
nitric oxide synthase 3 (endothelial cell)
decreases expression
EXP
7
150,688,144
150,711,687
RGD:6480464
CTD
G
NOS3
nitric oxide synthase 3 (endothelial cell)
decreases expression
EXP
7
150,688,144
150,711,687
RGD:6480464
CTD
G
NOS3
nitric oxide synthase 3 (endothelial cell)
increases phosphorylation
ISO
7
150,688,144
150,711,687
RGD:6480464
CTD
G
NPHS2
nephrosis 2, idiopathic, steroid-resistant (podocin)
affects expression
ISO
1
179,519,674
179,545,084
RGD:6480464
CTD
G
NPPA
natriuretic peptide A
multiple interactions
ISO
1
11,905,766
11,907,840
RGD:6480464
CTD
G
NQO1
NAD(P)H dehydrogenase, quinone 1
multiple interactions
ISO
16
69,743,304
69,760,533
RGD:6480464
CTD
G
NR1H3
nuclear receptor subfamily 1, group H, member 3
affects expression
EXP
11
47,269,851
47,290,584
RGD:6480464
CTD
G
NR1H4
nuclear receptor subfamily 1, group H, member 4
multiple interactions
EXP
12
100,867,551
100,957,645
RGD:6480464
CTD
G
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
increases activity
ISO
5
142,657,496
142,815,077
RGD:6480464
CTD
G
NXT1
NTF2-like export factor 1
decreases expression
ISO
20
23,331,373
23,335,408
RGD:6480464
CTD
G
OGN
osteoglycin
increases expression
ISO
9
95,146,249
95,166,937
RGD:6480464
CTD
G
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
affects expression
EXP
12
10,310,899
10,324,790
RGD:6480464
CTD
G
OXA1L
oxidase (cytochrome c) assembly 1-like
multiple interactions
EXP
14
23,235,731
23,240,998
RGD:6480464
CTD
G
PARP1
poly (ADP-ribose) polymerase 1
multiple interactions
EXP
1
226,548,392
226,595,801
RGD:6480464
CTD
G
PARP1
poly (ADP-ribose) polymerase 1
multiple interactions
EXP
1
226,548,392
226,595,801
RGD:6480464
CTD
G
PAX8
paired box 8
multiple interactions
EXP
2
113,973,574
114,036,498
RGD:6480464
CTD
G
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
multiple interactions
ISO
20
56,136,137
56,141,513
RGD:6480464
CTD
G
PCNA
proliferating cell nuclear antigen
multiple interactions
EXP
20
5,095,599
5,107,268
RGD:6480464
CTD
G
PCNA
proliferating cell nuclear antigen
decreases expression
EXP
20
5,095,599
5,107,268
RGD:6480464
CTD
G
PCNA
proliferating cell nuclear antigen
multiple interactions
ISO
20
5,095,599
5,107,268
RGD:6480464
CTD
G
PDCD4
programmed cell death 4 (neoplastic transformation inhibitor)
multiple interactions
EXP
10
112,631,553
112,659,764
RGD:6480464
CTD
G
PDCD4
programmed cell death 4 (neoplastic transformation inhibitor)
increases expression
EXP
10
112,631,553
112,659,764
RGD:6480464
CTD
G
PDGFB
platelet-derived growth factor beta polypeptide
multiple interactions
EXP
22
39,619,685
39,640,957
RGD:6480464
CTD
G
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
decreases response to substance
EXP
3
178,866,311
178,952,500
RGD:6480464
CTD
G
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
multiple interactions
EXP
3
178,866,311
178,952,500
RGD:6480464
CTD
G
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
increases activity
EXP
3
178,866,311
178,952,500
RGD:6480464
CTD
G
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
multiple interactions
EXP
5
67,511,584
67,597,649
RGD:6480464
CTD
G
PKM
pyruvate kinase, muscle
multiple interactions
EXP
15
72,491,370
72,523,727
RGD:6480464
CTD
G
PKP4
plakophilin 4
increases expression
ISO
2
159,313,476
159,537,941
RGD:6480464
CTD
G
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
multiple interactions
EXP
18
57,567,192
57,571,538
RGD:6480464
CTD
G
PMP22
peripheral myelin protein 22
increases metabolic processing
ISO
17
15,133,096
15,168,644
RGD:6480464
CTD
G
PNPLA2
patatin-like phospholipase domain containing 2
increases expression
ISO
11
818,901
825,573
RGD:6480464
CTD
G
POLD2
polymerase (DNA directed), delta 2, accessory subunit
decreases expression
ISO
7
44,154,279
44,163,169
RGD:6480464
CTD
G
POSTN
periostin, osteoblast specific factor
multiple interactions
ISO
13
38,136,719
38,172,981
RGD:6480464
CTD
G
POU5F1
POU class 5 homeobox 1
increases expression
ISO
6
31,132,114
31,138,451
RGD:6480464
CTD
G
PPARG
peroxisome proliferator-activated receptor gamma
affects expression
EXP
3
12,329,349
12,475,855
RGD:6480464
CTD
G
PPARG
peroxisome proliferator-activated receptor gamma
multiple interactions
EXP
3
12,329,349
12,475,855
RGD:6480464
CTD
G
PPARG
peroxisome proliferator-activated receptor gamma
decreases expression
ISO
3
12,329,349
12,475,855
RGD:6480464
CTD
G
PPL
periplakin
increases expression
ISO
16
4,932,508
4,987,136
RGD:6480464
CTD
G
PPP1R1B
protein phosphatase 1, regulatory (inhibitor) subunit 1B
multiple interactions
ISO
17
37,783,177
37,792,878
RGD:6480464
CTD
G
PRCP
prolylcarboxypeptidase (angiotensinase C)
increases expression
ISO
11
82,535,409
82,611,557
RGD:6480464
CTD
G
PRF1
perforin 1 (pore forming protein)
decreases expression
EXP
10
72,357,104
72,362,531
RGD:6480464
CTD
G
PRKAA1
protein kinase, AMP-activated, alpha 1 catalytic subunit
multiple interactions
ISO
5
40,759,481
40,798,297
RGD:6480464
CTD
G
PRKCD
protein kinase C, delta
affects localization
EXP
3
53,195,223
53,226,733
RGD:6480464
CTD
G
PRKCD
protein kinase C, delta
decreases phosphorylation
EXP
3
53,195,223
53,226,733
RGD:6480464
CTD
G
PRKCD
protein kinase C, delta
multiple interactions
EXP
3
53,195,223
53,226,733
RGD:6480464
CTD
G
PRKCG
protein kinase C, gamma
increases degradation
EXP
19
54,385,467
54,410,901
RGD:6480464
CTD
G
PRKCG
protein kinase C, gamma
multiple interactions
EXP
19
54,385,467
54,410,901
RGD:6480464
CTD
G
PRKCH
protein kinase C, eta
multiple interactions
EXP
14
61,788,515
62,017,698
RGD:6480464
CTD
G
PRKCH
protein kinase C, eta
decreases response to substance
EXP
14
61,788,515
62,017,698
RGD:6480464
CTD
G
PRLR
prolactin receptor
decreases expression
ISO
5
35,048,861
35,230,823
RGD:6480464
CTD
G
PSMA1
proteasome (prosome, macropain) subunit, alpha type, 1
decreases expression
ISO
11
14,526,422
14,665,180
RGD:6480464
CTD
G
PSMA4
proteasome (prosome, macropain) subunit, alpha type, 4
decreases expression
ISO
15
78,832,747
78,841,562
RGD:6480464
CTD
G
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
decreases expression
EXP
17
30,771,481
30,810,337
RGD:6480464
CTD
G
PTEN
phosphatase and tensin homolog
multiple interactions
EXP
10
89,623,195
89,728,532
RGD:6480464
CTD
G
PTEN
phosphatase and tensin homolog
decreases response to substance
EXP
10
89,623,195
89,728,532
RGD:6480464
CTD
G
PTEN
phosphatase and tensin homolog
decreases expression
ISO
10
89,623,195
89,728,532
RGD:6480464
CTD
G
PTEN
phosphatase and tensin homolog
multiple interactions
ISO
10
89,623,195
89,728,532
RGD:6480464
CTD
G
PTGER1
prostaglandin E receptor 1 (subtype EP1), 42kDa
multiple interactions
EXP
19
14,583,278
14,586,174
RGD:6480464
CTD
G
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
multiple interactions
ISO
1
186,640,944
186,649,559
RGD:6480464
CTD
G
PTK2
protein tyrosine kinase 2
decreases phosphorylation
ISO
8
141,668,481
142,011,412
RGD:6480464
CTD
G
PTPRC
protein tyrosine phosphatase, receptor type, C
increases expression
ISO
1
198,608,098
198,726,605
RGD:6480464
CTD
G
PTTG1
pituitary tumor-transforming 1
multiple interactions
EXP
5
159,848,865
159,855,746
RGD:6480464
CTD
G
RAC1
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
decreases expression
ISO
7
6,414,126
6,443,598
RGD:6480464
CTD
G
RAC1
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
multiple interactions
ISO
7
6,414,126
6,443,598
RGD:6480464
CTD
G
RAD51
RAD51 homolog (S. cerevisiae)
multiple interactions
EXP
15
40,987,327
41,024,356
RGD:6480464
CTD
G
RAF1
v-raf-1 murine leukemia viral oncogene homolog 1
multiple interactions
EXP
3
12,625,100
12,705,700
RGD:6480464
CTD
G
RB1
retinoblastoma 1
multiple interactions
EXP
13
48,877,883
49,056,026
RGD:6480464
CTD
G
RB1
retinoblastoma 1
multiple interactions
EXP
13
48,877,883
49,056,026
RGD:6480464
CTD
G
RB1
retinoblastoma 1
multiple interactions
EXP
13
48,877,883
49,056,026
RGD:6480464
CTD
G
RB1
retinoblastoma 1
multiple interactions
EXP
13
48,877,883
49,056,026
RGD:6480464
CTD
G
RB1
retinoblastoma 1
multiple interactions
EXP
13
48,877,883
49,056,026
RGD:6480464
CTD
G
RB1
retinoblastoma 1
decreases phosphorylation
EXP
13
48,877,883
49,056,026
RGD:6480464
CTD
G
RB1
retinoblastoma 1
multiple interactions
EXP
13
48,877,883
49,056,026
RGD:6480464
CTD
G
RB1
retinoblastoma 1
multiple interactions
ISO
13
48,877,883
49,056,026
RGD:6480464
CTD
G
RB1
retinoblastoma 1
multiple interactions
ISO
13
48,877,883
49,056,026
RGD:6480464
CTD
G
RB1
retinoblastoma 1
decreases phosphorylation
ISO
13
48,877,883
49,056,026
RGD:6480464
CTD
G
RB1
retinoblastoma 1
multiple interactions
ISO
13
48,877,883
49,056,026
RGD:6480464
CTD
G
RB1
retinoblastoma 1
decreases phosphorylation
EXP
13
48,877,883
49,056,026
RGD:6480464
CTD
G
RB1
retinoblastoma 1
decreases phosphorylation
EXP
13
48,877,883
49,056,026
RGD:6480464
CTD
G
RB1
retinoblastoma 1
decreases phosphorylation
EXP
13
48,877,883
49,056,026
RGD:6480464
CTD
G
RB1
retinoblastoma 1
decreases phosphorylation
EXP
13
48,877,883
49,056,026
RGD:6480464
CTD
G
RB1
retinoblastoma 1
decreases phosphorylation
EXP
13
48,877,883
49,056,026
RGD:6480464
CTD
G
RB1
retinoblastoma 1
decreases phosphorylation
EXP
13
48,877,883
49,056,026
RGD:6480464
CTD
G
RBL1
retinoblastoma-like 1 (p107)
multiple interactions
EXP
20
35,626,178
35,724,410
RGD:6480464
CTD
G
RBL2
retinoblastoma-like 2 (p130)
multiple interactions
EXP
16
53,468,351
53,525,560
RGD:6480464
CTD
G
RBL2
retinoblastoma-like 2 (p130)
multiple interactions
EXP
16
53,468,351
53,525,560
RGD:6480464
CTD
G
RELA
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
multiple interactions
EXP
11
65,421,067
65,430,443
RGD:6480464
CTD
G
RELA
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
multiple interactions
EXP
11
65,421,067
65,430,443
RGD:6480464
CTD
G
RELA
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
multiple interactions
EXP
11
65,421,067
65,430,443
RGD:6480464
CTD
G
RELA
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
multiple interactions
ISO
11
65,421,067
65,430,443
RGD:6480464
CTD
G
RELA
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
multiple interactions
ISO
11
65,421,067
65,430,443
RGD:6480464
CTD
G
REN
renin
increases expression
ISO
1
204,123,944
204,135,465
RGD:6480464
CTD
G
REST
RE1-silencing transcription factor
multiple interactions
EXP
4
57,774,042
57,802,010
RGD:6480464
CTD
G
RICTOR
RPTOR independent companion of MTOR, complex 2
decreases expression
EXP
5
38,938,022
39,074,501
RGD:6480464
CTD
G
RPL7P26
ribosomal protein L7 pseudogene 26
multiple interactions
EXP
6
17,531,059
17,531,588
RGD:6480464
CTD
G
RPS27L
ribosomal protein S27-like
multiple interactions
EXP
15
63,445,539
63,449,741
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
multiple interactions
EXP
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
multiple interactions
EXP
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
multiple interactions
EXP
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
multiple interactions
EXP
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
multiple interactions
ISO
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
decreases phosphorylation
EXP
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
multiple interactions
EXP
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
multiple interactions
ISO
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
decreases phosphorylation
ISO
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
decreases phosphorylation
EXP
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
decreases phosphorylation
ISO
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
decreases phosphorylation
EXP
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
decreases phosphorylation
EXP
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
decreases phosphorylation
EXP
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
multiple interactions
EXP
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
decreases phosphorylation
EXP
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
decreases phosphorylation
EXP
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
multiple interactions
ISO
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
decreases phosphorylation
EXP
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
multiple interactions
ISO
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
decreases phosphorylation
ISO
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
multiple interactions
ISO
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
multiple interactions
EXP
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
increases phosphorylation
EXP
1
26,856,249
26,901,520
RGD:6480464
CTD
G
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
affects localization
ISO
1
26,856,249
26,901,520
RGD:6480464
CTD
G
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
increases phosphorylation
ISO
1
26,856,249
26,901,520
RGD:6480464
CTD
G
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
multiple interactions
ISO
1
26,856,249
26,901,520
RGD:6480464
CTD
G
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
affects localization
ISO
6
166,822,854
167,275,771
RGD:6480464
CTD
G
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
increases phosphorylation
ISO
6
166,822,854
167,275,771
RGD:6480464
CTD
G
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
affects localization
ISO
X
20,168,029
20,284,750
RGD:6480464
CTD
G
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
increases phosphorylation
ISO
X
20,168,029
20,284,750
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
decreases activity
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
decreases activity
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
ISO
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
ISO
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
decreases phosphorylation
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
ISO
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
ISO
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
decreases activity
ISO
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
ISO
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
decreases phosphorylation
ISO
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
ISO
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
ISO
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
ISO
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
decreases phosphorylation
ISO
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
decreases phosphorylation
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
decreases phosphorylation
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
decreases phosphorylation
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
decreases phosphorylation
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
ISO
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
ISO
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
decreases phosphorylation
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
decreases phosphorylation
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
decreases activity
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
ISO
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
ISO
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
decreases phosphorylation
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
decreases phosphorylation
ISO
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
decreases phosphorylation
ISO
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
decreases phosphorylation
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
ISO
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB2
ribosomal protein S6 kinase, 70kDa, polypeptide 2
multiple interactions
EXP
11
67,195,935
67,202,879
RGD:6480464
CTD
G
RPS6KB2
ribosomal protein S6 kinase, 70kDa, polypeptide 2
decreases activity
EXP
11
67,195,935
67,202,879
RGD:6480464
CTD
G
RPTOR
regulatory associated protein of MTOR, complex 1
multiple interactions
EXP
17
78,518,625
78,940,173
RGD:6480464
CTD
G
RPTOR
regulatory associated protein of MTOR, complex 1
multiple interactions
EXP
17
78,518,625
78,940,173
RGD:6480464
CTD
G
RPTOR
regulatory associated protein of MTOR, complex 1
multiple interactions
EXP
17
78,518,625
78,940,173
RGD:6480464
CTD
G
RPTOR
regulatory associated protein of MTOR, complex 1
multiple interactions
EXP
17
78,518,625
78,940,173
RGD:6480464
CTD
G
RRAD
Ras-related associated with diabetes
multiple interactions
EXP
16
66,955,582
66,959,439
RGD:6480464
CTD
G
S100A4
S100 calcium binding protein A4
decreases expression
ISO
1
153,516,095
153,518,282
RGD:6480464
CTD
G
S100G
S100 calcium binding protein G
increases expression
ISO
X
16,668,281
16,672,791
RGD:6480464
CTD
G
SCARB2
scavenger receptor class B, member 2
decreases expression
EXP
4
77,079,890
77,135,052
RGD:6480464
CTD
G
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
multiple interactions
EXP
10
102,106,772
102,124,588
RGD:6480464
CTD
G
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
multiple interactions
EXP
7
80,371,854
80,548,667
RGD:6480464
CTD
G
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
affects localization
EXP
14
94,843,084
94,857,029
RGD:6480464
CTD
G
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
increases expression
ISO
14
95,078,714
95,090,390
RGD:6480464
CTD
G
SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
multiple interactions
EXP
7
100,770,370
100,782,547
RGD:6480464
CTD
G
SIRT1
sirtuin 1
multiple interactions
EXP
10
69,644,427
69,678,147
RGD:6480464
CTD
G
SIRT1
sirtuin 1
decreases expression
EXP
10
69,644,427
69,678,147
RGD:6480464
CTD
G
SIRT2
sirtuin 2
multiple interactions
EXP
19
39,369,195
39,390,502
RGD:6480464
CTD
G
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
decreases expression
EXP
5
36,152,145
36,184,143
RGD:6480464
CTD
G
SLC12A1
solute carrier family 12 (sodium/potassium/chloride transporters), member 1
multiple interactions
ISO
15
48,498,498
48,596,275
RGD:6480464
CTD
G
SLC12A1
solute carrier family 12 (sodium/potassium/chloride transporters), member 1
decreases expression
ISO
15
48,498,498
48,596,275
RGD:6480464
CTD
G
SLC12A3
solute carrier family 12 (sodium/chloride transporters), member 3
increases expression
ISO
16
56,899,119
56,949,762
RGD:6480464
CTD
G
SLC15A1
solute carrier family 15 (oligopeptide transporter), member 1
multiple interactions
EXP
13
99,336,055
99,404,929
RGD:6480464
CTD
G
SLC16A1
solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
decreases expression
ISO
1
113,454,469
113,498,975
RGD:6480464
CTD
G
SLC22A13
solute carrier family 22 (organic anion transporter), member 13
decreases expression
ISO
3
38,307,298
38,319,806
RGD:6480464
CTD
G
SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
decreases expression
ISO
22
32,439,019
32,509,016
RGD:6480464
CTD
G
SLCO1A2
solute carrier organic anion transporter family, member 1A2
increases expression
ISO
12
21,417,534
21,548,371
RGD:6480464
CTD
G
SMIM14
small integral membrane protein 14
multiple interactions
EXP
4
39,552,550
39,640,481
RGD:6480464
CTD
G
SOX2
SRY (sex determining region Y)-box 2
increases expression
ISO
3
181,429,712
181,432,224
RGD:6480464
CTD
G
SQSTM1
sequestosome 1
decreases expression
EXP
5
179,233,388
179,265,078
RGD:6480464
CTD
G
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
multiple interactions
ISO
20
35,973,088
36,033,821
RGD:6480464
CTD
G
SREBF1
sterol regulatory element binding transcription factor 1
decreases expression
ISO
17
17,714,663
17,740,325
RGD:6480464
CTD
G
STARD10
StAR-related lipid transfer (START) domain containing 10
multiple interactions
EXP
11
72,465,774
72,504,750
RGD:6480464
CTD
G
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
decreases phosphorylation
EXP
17
40,465,343
40,540,513
RGD:6480464
CTD
G
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
multiple interactions
EXP
17
40,465,343
40,540,513
RGD:6480464
CTD
G
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
decreases phosphorylation
ISO
17
40,465,343
40,540,513
RGD:6480464
CTD
G
STRA13
stimulated by retinoic acid 13
increases expression
ISO
17
79,976,579
79,980,785
RGD:6480464
CTD
G
STS
steroid sulfatase (microsomal), isozyme S
multiple interactions
EXP
X
7,137,472
7,272,682
RGD:6480464
CTD
G
SYT1
synaptotagmin I
multiple interactions
EXP
12
79,257,773
79,845,788
RGD:6480464
CTD
G
TAF12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
decreases expression
ISO
1
28,929,608
28,969,604
RGD:6480464
CTD
G
TAL1
T-cell acute lymphocytic leukemia 1
multiple interactions
EXP
1
47,681,963
47,695,443
RGD:6480464
CTD
G
TARS
threonyl-tRNA synthetase
decreases expression
ISO
5
33,440,802
33,468,196
RGD:6480464
CTD
G
TAX1BP1
Tax1 (human T-cell leukemia virus type I) binding protein 1
increases expression
ISO
7
27,778,992
27,869,386
RGD:6480464
CTD
G
TCF19
transcription factor 19
multiple interactions
EXP
6
31,126,303
31,131,992
RGD:6480464
CTD
G
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
multiple interactions
EXP
11
12,695,969
12,966,284
RGD:6480464
CTD
G
TERT
telomerase reverse transcriptase
decreases expression
EXP
5
1,253,282
1,295,162
RGD:6480464
CTD
G
TERT
telomerase reverse transcriptase
decreases expression
EXP
5
1,253,282
1,295,162
RGD:6480464
CTD
G
TERT
telomerase reverse transcriptase
decreases expression
EXP
5
1,253,282
1,295,162
RGD:6480464
CTD
G
TERT
telomerase reverse transcriptase
decreases expression
EXP
5
1,253,282
1,295,162
RGD:6480464
CTD
G
TERT
telomerase reverse transcriptase
decreases expression
EXP
5
1,253,282
1,295,162
RGD:6480464
CTD
G
TERT
telomerase reverse transcriptase
decreases expression
EXP
5
1,253,282
1,295,162
RGD:6480464
CTD
G
TGFB1
transforming growth factor, beta 1
multiple interactions
EXP
19
41,836,812
41,859,831
RGD:6480464
CTD
G
TGFB1
transforming growth factor, beta 1
multiple interactions
EXP
19
41,836,812
41,859,831
RGD:6480464
CTD
G
TGFB1
transforming growth factor, beta 1
multiple interactions
EXP
19
41,836,812
41,859,831
RGD:6480464
CTD
G
TGFB1
transforming growth factor, beta 1
multiple interactions
EXP
19
41,836,812
41,859,831
RGD:6480464
CTD
G
TGFB1
transforming growth factor, beta 1
multiple interactions
ISO
19
41,836,812
41,859,831
RGD:6480464
CTD
G
TGFB1
transforming growth factor, beta 1
increases response to substance
EXP
19
41,836,812
41,859,831
RGD:6480464
CTD
G
TGFB1
transforming growth factor, beta 1
multiple interactions
ISO
19
41,836,812
41,859,831
RGD:6480464
CTD
G
TGFB1
transforming growth factor, beta 1
multiple interactions
ISO
19
41,836,812
41,859,831
RGD:6480464
CTD
G
TGFB1
transforming growth factor, beta 1
multiple interactions
ISO
19
41,836,812
41,859,831
RGD:6480464
CTD
G
TGFB1
transforming growth factor, beta 1
multiple interactions
ISO
19
41,836,812
41,859,831
RGD:6480464
CTD
G
TGFBR3
transforming growth factor, beta receptor III
increases expression
ISO
1
92,145,900
92,371,559
RGD:6480464
CTD
G
TGM2
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
decreases expression
ISO
20
36,756,863
36,793,700
RGD:6480464
CTD
G
TIMELESS
timeless circadian clock
multiple interactions
EXP
12
56,810,157
56,843,200
RGD:6480464
CTD
G
TIMP3
TIMP metallopeptidase inhibitor 3
decreases expression
EXP
22
33,196,802
33,259,028
RGD:6480464
CTD
G
TMEM14C
transmembrane protein 14C
multiple interactions
EXP
6
10,723,148
10,731,362
RGD:6480464
CTD
G
TNF
tumor necrosis factor
multiple interactions
EXP
6
31,543,344
31,546,113
RGD:6480464
CTD
G
TNF
tumor necrosis factor
increases expression
EXP
6
31,543,344
31,546,113
RGD:6480464
CTD
G
TNF
tumor necrosis factor
multiple interactions
ISO
6
31,543,344
31,546,113
RGD:6480464
CTD
G
TNF
tumor necrosis factor
multiple interactions
ISO
6
31,543,344
31,546,113
RGD:6480464
CTD
G
TNF
tumor necrosis factor
decreases secretion
ISO
6
31,543,344
31,546,113
RGD:6480464
CTD
G
TNF
tumor necrosis factor
multiple interactions
ISO
6
31,543,344
31,546,113
RGD:6480464
CTD
G
TNF
tumor necrosis factor
multiple interactions
ISO
6
31,543,344
31,546,113
RGD:6480464
CTD
G
TNF
tumor necrosis factor
multiple interactions
ISO
6
31,543,344
31,546,113
RGD:6480464
CTD
G
TNFSF11
tumor necrosis factor (ligand) superfamily, member 11
multiple interactions
ISO
13
43,136,872
43,182,149
RGD:6480464
CTD
G
TP53
tumor protein p53
multiple interactions
EXP
17
7,571,720
7,590,868
RGD:6480464
CTD
G
TP53
tumor protein p53
decreases phosphorylation
EXP
17
7,571,720
7,590,868
RGD:6480464
CTD
G
TP53
tumor protein p53
multiple interactions
EXP
17
7,571,720
7,590,868
RGD:6480464
CTD
G
TP63
tumor protein p63
decreases expression
ISO
3
189,349,216
189,615,068
RGD:6480464
CTD
G
TP63
tumor protein p63
decreases expression
EXP
3
189,349,216
189,615,068
RGD:6480464
CTD
G
TP73
tumor protein p73
multiple interactions
EXP
1
3,569,129
3,652,765
RGD:6480464
CTD
G
TP73
tumor protein p73
multiple interactions
EXP
1
3,569,129
3,652,765
RGD:6480464
CTD
G
TP73
tumor protein p73
increases expression
EXP
1
3,569,129
3,652,765
RGD:6480464
CTD
G
TPP2
tripeptidyl peptidase II
multiple interactions
ISO
13
103,249,286
103,331,524
RGD:6480464
CTD
G
TRPM6
transient receptor potential cation channel, subfamily M, member 6
multiple interactions
ISO
9
77,337,411
77,503,010
RGD:6480464
CTD
G
TRPM6
transient receptor potential cation channel, subfamily M, member 6
increases expression
ISO
9
77,337,411
77,503,010
RGD:6480464
CTD
G
TSC1
tuberous sclerosis 1
multiple interactions
ISO
9
135,766,735
135,820,020
RGD:6480464
CTD
G
TSC2
tuberous sclerosis 2
multiple interactions
ISO
16
2,097,990
2,138,713
RGD:6480464
CTD
G
TTK
TTK protein kinase
multiple interactions
EXP
6
80,714,322
80,752,244
RGD:6480464
CTD
G
TYMS
thymidylate synthetase
decreases expression
EXP
18
657,604
673,499
RGD:6480464
CTD
G
TYMS
thymidylate synthetase
decreases expression
EXP
18
657,604
673,499
RGD:6480464
CTD
G
URI1
URI1, prefoldin-like chaperone
decreases response to substance
EXP
19
30,414,551
30,507,519
RGD:6480464
CTD
G
VASN
vasorin
decreases expression
ISO
16
4,421,849
4,433,529
RGD:6480464
CTD
G
VCAN
versican
increases expression
ISO
5
82,767,493
82,878,122
RGD:6480464
CTD
G
VEGFA
vascular endothelial growth factor A
multiple interactions
EXP
6
43,737,946
43,754,224
RGD:6480464
CTD
G
VEGFA
vascular endothelial growth factor A
multiple interactions
EXP
6
43,737,946
43,754,224
RGD:6480464
CTD
G
VEGFA
vascular endothelial growth factor A
multiple interactions
EXP
6
43,737,946
43,754,224
RGD:6480464
CTD
G
VEGFA
vascular endothelial growth factor A
decreases expression
EXP
6
43,737,946
43,754,224
RGD:6480464
CTD
G
WT1
Wilms tumor 1
decreases expression
EXP
11
32,409,321
32,457,081
RGD:6480464
CTD
G
WT1
Wilms tumor 1
decreases expression
EXP
11
32,409,321
32,457,081
RGD:6480464
CTD
G
XBP1
X-box binding protein 1
multiple interactions
EXP
22
29,190,548
29,196,560
RGD:6480464
CTD
G
XIAP
X-linked inhibitor of apoptosis
multiple interactions
EXP
X
122,993,662
123,047,829
RGD:6480464
CTD
G
YPEL1
yippee-like 1 (Drosophila)
multiple interactions
EXP
22
22,051,825
22,090,071
RGD:6480464
CTD
G
ZIC2
Zic family member 2
multiple interactions
EXP
13
100,634,026
100,639,019
RGD:6480464
CTD
G
ZNRD1
zinc ribbon domain containing 1
multiple interactions
EXP
6
30,029,036
30,032,686
RGD:6480464
CTD
G
ZWINT
ZW10 interactor, kinetochore protein
multiple interactions
EXP
10
58,117,199
58,121,034
RGD:6480464
CTD
everolimus
G
AKT1
v-akt murine thymoma viral oncogene homolog 1
decreases phosphorylation
EXP
14
105,235,686
105,262,080
RGD:6480464
CTD
G
AKT1
v-akt murine thymoma viral oncogene homolog 1
increases phosphorylation
EXP
14
105,235,686
105,262,080
RGD:6480464
CTD
G
AKT1
v-akt murine thymoma viral oncogene homolog 1
increases phosphorylation
EXP
14
105,235,686
105,262,080
RGD:6480464
CTD
G
BIRC5
baculoviral IAP repeat containing 5
decreases expression
EXP
17
76,210,277
76,221,716
RGD:6480464
CTD
G
CASP3
caspase 3, apoptosis-related cysteine peptidase
increases cleavage
EXP
4
185,548,850
185,570,629
RGD:6480464
CTD
G
CCNA2
cyclin A2
decreases expression
EXP
4
122,737,599
122,745,088
RGD:6480464
CTD
G
CCND1
cyclin D1
multiple interactions
EXP
11
69,455,873
69,469,242
RGD:6480464
CTD
G
CCND1
cyclin D1
decreases expression
EXP
11
69,455,873
69,469,242
RGD:6480464
CTD
G
CCND2
cyclin D2
multiple interactions
EXP
12
4,382,902
4,414,522
RGD:6480464
CTD
G
CCND2
cyclin D2
decreases expression
EXP
12
4,382,902
4,414,522
RGD:6480464
CTD
G
CCND3
cyclin D3
decreases expression
EXP
6
41,902,671
42,016,610
RGD:6480464
CTD
G
EIF4E
eukaryotic translation initiation factor 4E
increases phosphorylation
EXP
4
99,799,607
99,851,786
RGD:6480464
CTD
G
EIF4E
eukaryotic translation initiation factor 4E
multiple interactions
EXP
4
99,799,607
99,851,786
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
multiple interactions
EXP
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
decreases phosphorylation
EXP
8
37,888,020
37,917,883
RGD:6480464
CTD
G
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
multiple interactions
EXP
3
184,032,283
184,053,146
RGD:6480464
CTD
G
F3
coagulation factor III (thromboplastin, tissue factor)
multiple interactions
EXP
1
94,994,732
95,007,413
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases activity
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
decreases activity
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
MTOR
mechanistic target of rapamycin (serine/threonine kinase)
multiple interactions
EXP
1
11,166,588
11,322,608
RGD:6480464
CTD
G
NOS3
nitric oxide synthase 3 (endothelial cell)
decreases expression
EXP
7
150,688,144
150,711,687
RGD:6480464
CTD
G
NOS3
nitric oxide synthase 3 (endothelial cell)
multiple interactions
EXP
7
150,688,144
150,711,687
RGD:6480464
CTD
G
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
increases expression
ISO
1
186,640,944
186,649,559
RGD:6480464
CTD
G
RB1
retinoblastoma 1
multiple interactions
EXP
13
48,877,883
49,056,026
RGD:6480464
CTD
G
RB1
retinoblastoma 1
decreases phosphorylation
EXP
13
48,877,883
49,056,026
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
decreases phosphorylation
EXP
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
decreases phosphorylation
EXP
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6
ribosomal protein S6
multiple interactions
EXP
9
19,376,254
19,380,235
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
multiple interactions
EXP
17
57,970,443
58,027,787
RGD:6480464
CTD
G
SIRT1
sirtuin 1
multiple interactions
EXP
10
69,644,427
69,678,147
RGD:6480464
CTD
G
SIRT1
sirtuin 1
decreases expression
EXP
10
69,644,427
69,678,147
RGD:6480464
CTD
G
TNF
tumor necrosis factor
multiple interactions
EXP
6
31,543,344
31,546,113
RGD:6480464
CTD
Term paths to the root one longest all shortest one shortest all one shortest and longest all longest