ONTOLOGY REPORT - ANNOTATIONS

Term:medroxyprogesterone
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Accession:CHEBI:6715 term browser browse the term
Definition:A 17alpha-hydroxy steroid that has formula C22H32O3.
Synonyms:exact_synonym: (6alpha)-17-hydroxy-6-methylpregn-4-ene-3,20-dione
 related_synonym: 17-Hydroxy-6alpha-methyl-pregn-4-ene-3,20-dione;   17-Hydroxy-6alpha-methylprogesterone;   17alpha-Hydroxy-6alpha-methylprogesterone;   6alpha-Methyl-17alpha-hydroxyprogesterone;   6alpha-Methyl-4-pregnen-17alpha-ol-3,20-dione;   C22H32O3;   InChI=1S/C22H32O3/c1-13-11-16-17(20(3)8-5-15(24)12-19(13)20)6-9-21(4)18(16)7-10-22(21,25)14(2)23/h12-13,16-18,25H,5-11H2,1-4H3/t13-,16+,17-,18-,20+,21-,22-/m0/s1;   InChIKey=FRQMUZJSZHZSGN-HBNHAYAOSA-N;   Medroxyprogesteron;   [H][C@@]12C[C@H](C)C3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(C)=O;   medroxiprogesterona;   medroxyprogesteronum
 xref_casrn: 520-85-4
 xref: Beilstein:2510965 "Beilstein Registry Number";   ChEMBL:428173 "ChEMBL COMPOUND";   ChemIDplus:520-85-4 "CAS Registry Number";   DrugBank:DB00603 "DrugBank";   KEGG COMPOUND:C07119 "KEGG COMPOUND";   KEGG DRUG:D08166 "KEGG DRUG"
 xref_mesh: MESH:D008525
 xref: Patent:GB866381 "Patent";   Patent:US3043832 "Patent";   Patent:US3061616 "Patent";   Patent:US3377364 "Patent"

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medroxyprogesterone term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Ar androgen receptor GBrowse link affects binding EXP X 85,949,507 86,119,199 RGD:6480464 CTD
G Cat catalase GBrowse link multiple interactions ISO 3 88,654,077 88,686,212 RGD:6480464 CTD
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 GBrowse link decreases activity ISO 1 244,400,004 244,493,624 RGD:6480464 CTD
G Fshb follicle stimulating hormone, beta polypeptide GBrowse link multiple interactions ISO 3 92,569,344 92,571,254 RGD:6480464 CTD
G Lpo lactoperoxidase GBrowse link multiple interactions ISO 10 76,099,137 76,118,724 RGD:6480464 CTD
medroxyprogesterone acetate term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Akr1c1 aldo-keto reductase family 1, member C1 GBrowse link decreases activity ISO 17 77,084,306 77,112,994 RGD:6480464 CTD
G Akr1c1 aldo-keto reductase family 1, member C1 GBrowse link decreases activity ISO 17 77,084,306 77,112,994 RGD:6480464 CTD
G Akr1c1 aldo-keto reductase family 1, member C1 GBrowse link decreases activity ISO 17 77,084,306 77,112,994 RGD:6480464 CTD
G Akr1c2 aldo-keto reductase family 1, member C2 GBrowse link decreases activity ISO 17 77,034,737 77,081,406 RGD:6480464 CTD
G Akr1c3 aldo-keto reductase family 1, member C3 GBrowse link decreases activity ISO 17 77,269,626 77,286,521 RGD:6480464 CTD
G Akr1c3 aldo-keto reductase family 1, member C3 GBrowse link decreases activity ISO 17 77,269,626 77,286,521 RGD:6480464 CTD
G Akr1c3 aldo-keto reductase family 1, member C3 GBrowse link multiple interactions ISO 17 77,269,626 77,286,521 RGD:6480464 CTD
G Akr1c3 aldo-keto reductase family 1, member C3 GBrowse link decreases activity ISO 17 77,269,626 77,286,521 RGD:6480464 CTD
G Akr1c3 aldo-keto reductase family 1, member C3 GBrowse link decreases activity ISO 17 77,269,626 77,286,521 RGD:6480464 CTD
G Ar androgen receptor GBrowse link affects binding ISO X 85,949,507 86,119,199 RGD:6480464 CTD
G Ar androgen receptor GBrowse link increases activity ISO X 85,949,507 86,119,199 RGD:6480464 CTD
G Ar androgen receptor GBrowse link affects binding EXP X 85,949,507 86,119,199 RGD:6480464 CTD
G Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide GBrowse link increases expression ISO 2 196,657,749 196,687,242 RGD:6480464 CTD
G Azgp1 alpha-2-glycoprotein 1, zinc-binding GBrowse link increases expression ISO 12 17,492,913 17,498,949 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link multiple interactions ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bcl2l11 BCL2-like 11 (apoptosis facilitator) GBrowse link multiple interactions ISO 3 115,692,323 115,722,701 RGD:6480464 CTD
G C3 complement component 3 multiple interactions EXP RGD:6480464 CTD
G C3 complement component 3 multiple interactions EXP RGD:6480464 CTD
G C3 complement component 3 multiple interactions EXP RGD:6480464 CTD
G Cat catalase GBrowse link multiple interactions ISO 3 88,654,077 88,686,212 RGD:6480464 CTD
G Cd40lg CD40 ligand GBrowse link multiple interactions ISO X 141,925,019 141,937,183 RGD:6480464 CTD
G Cd40lg CD40 ligand GBrowse link decreases activity ISO X 141,925,019 141,937,183 RGD:6480464 CTD
G Cdkn1b cyclin-dependent kinase inhibitor 1B GBrowse link multiple interactions ISO 4 171,841,705 171,846,506 RGD:6480464 CTD
G Cdkn1b cyclin-dependent kinase inhibitor 1B GBrowse link increases expression ISO 4 171,841,705 171,846,506 RGD:6480464 CTD
G Cflar CASP8 and FADD-like apoptosis regulator GBrowse link multiple interactions ISO 9 57,309,836 57,356,635 RGD:6480464 CTD
G Crebbp CREB binding protein GBrowse link multiple interactions ISO 10 11,598,680 11,724,122 RGD:6480464 CTD
G Crp C-reactive protein, pentraxin-related GBrowse link multiple interactions ISO 13 88,702,243 88,703,153 RGD:6480464 CTD
G Crp C-reactive protein, pentraxin-related GBrowse link multiple interactions ISO 13 88,702,243 88,703,153 RGD:6480464 CTD
G Cybb cytochrome b-245, beta polypeptide GBrowse link multiple interactions EXP X 25,514,572 25,547,181 RGD:6480464 CTD
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 GBrowse link multiple interactions ISO 8 61,462,207 61,468,237 RGD:6480464 CTD
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 GBrowse link multiple interactions ISO 6 2,548,224 2,553,767 RGD:6480464 CTD
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 GBrowse link increases expression ISO 12 9,517,016 9,541,000 RGD:6480464 CTD
G Ephx1 epoxide hydrolase 1, microsomal (xenobiotic) GBrowse link multiple interactions ISO 13 96,722,973 96,752,940 RGD:6480464 CTD
G Ephx1 epoxide hydrolase 1, microsomal (xenobiotic) GBrowse link increases expression ISO 13 96,722,973 96,752,940 RGD:6480464 CTD
G Esr1 estrogen receptor 1 GBrowse link multiple interactions ISO 1 35,523,680 35,759,891 RGD:6480464 CTD
G F2 coagulation factor II GBrowse link multiple interactions ISO 3 76,005,318 76,018,603 RGD:6480464 CTD
G F2 coagulation factor II GBrowse link increases expression ISO 3 76,005,318 76,018,603 RGD:6480464 CTD
G F2 coagulation factor II GBrowse link multiple interactions EXP 3 76,005,318 76,018,603 RGD:6480464 CTD
G F2r coagulation factor II (thrombin) receptor GBrowse link increases expression ISO 2 25,985,800 25,989,072 RGD:6480464 CTD
G F2r coagulation factor II (thrombin) receptor GBrowse link increases expression EXP 2 25,985,800 25,989,072 RGD:6480464 CTD
G F2r coagulation factor II (thrombin) receptor GBrowse link multiple interactions EXP 2 25,985,800 25,989,072 RGD:6480464 CTD
G F3 coagulation factor III (thromboplastin, tissue factor) GBrowse link multiple interactions ISO 2 218,371,050 218,382,645 RGD:6480464 CTD
G F3 coagulation factor III (thromboplastin, tissue factor) GBrowse link increases expression ISO 2 218,371,050 218,382,645 RGD:6480464 CTD
G F3 coagulation factor III (thromboplastin, tissue factor) GBrowse link multiple interactions EXP 2 218,371,050 218,382,645 RGD:6480464 CTD
G F7 coagulation factor VII (serum prothrombin conversion accelerator) GBrowse link decreases expression ISO 16 81,348,678 81,358,991 RGD:6480464 CTD
G F9 coagulation factor IX GBrowse link increases expression ISO X 145,527,978 145,575,966 RGD:6480464 CTD
G Faslg Fas ligand (TNF superfamily, member 6) GBrowse link multiple interactions ISO 13 77,472,950 77,480,210 RGD:6480464 CTD
G Fbln1 fibulin 1 GBrowse link increases expression ISO 7 123,208,154 123,287,289 RGD:6480464 CTD
G Fbln1 fibulin 1 GBrowse link multiple interactions ISO 7 123,208,154 123,287,289 RGD:6480464 CTD
G Fn1 fibronectin 1 GBrowse link multiple interactions ISO 9 70,702,181 70,771,155 RGD:6480464 CTD
G Foxo1 forkhead box O1 GBrowse link multiple interactions ISO 2 141,127,345 141,203,446 RGD:6480464 CTD
G Foxo3 forkhead box O3 GBrowse link multiple interactions ISO 20 46,171,784 46,262,818 RGD:6480464 CTD
G Fshb follicle stimulating hormone, beta polypeptide GBrowse link multiple interactions ISO 3 92,569,344 92,571,254 RGD:6480464 CTD
G Gadd45a growth arrest and DNA-damage-inducible, alpha GBrowse link multiple interactions ISO 4 96,649,941 96,652,243 RGD:6480464 CTD
G Gsta2 glutathione S-transferase alpha 2 GBrowse link increases expression EXP 8 83,299,249 83,312,958 RGD:6480464 CTD
G Hoxa11 homeobox A11 GBrowse link increases expression ISO 4 80,542,417 80,546,079 RGD:6480464 CTD
G Hoxa11 homeobox A11 GBrowse link increases expression ISO 4 80,542,417 80,546,079 RGD:6480464 CTD
G Icam1 intercellular adhesion molecule 1 GBrowse link multiple interactions ISO 8 20,040,177 20,051,939 RGD:6480464 CTD
G Ifng interferon gamma GBrowse link multiple interactions ISO 7 57,621,756 57,625,792 RGD:6480464 CTD
G Igfbp1 insulin-like growth factor binding protein 1 GBrowse link increases expression ISO 14 87,950,222 87,955,289 RGD:6480464 CTD
G Igfbp1 insulin-like growth factor binding protein 1 GBrowse link multiple interactions ISO 14 87,950,222 87,955,289 RGD:6480464 CTD
G Igfbp1 insulin-like growth factor binding protein 1 GBrowse link multiple interactions ISO 14 87,950,222 87,955,289 RGD:6480464 CTD
G Igfbp1 insulin-like growth factor binding protein 1 GBrowse link multiple interactions ISO 14 87,950,222 87,955,289 RGD:6480464 CTD
G Igfbp1 insulin-like growth factor binding protein 1 GBrowse link increases expression ISO 14 87,950,222 87,955,289 RGD:6480464 CTD
G Igfbp1 insulin-like growth factor binding protein 1 GBrowse link increases expression ISO 14 87,950,222 87,955,289 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link multiple interactions ISO 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il2 interleukin 2 GBrowse link multiple interactions ISO 2 123,655,005 123,659,709 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link multiple interactions ISO 4 456,799 461,376 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link multiple interactions ISO 4 456,799 461,376 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link decreases secretion ISO 4 456,799 461,376 RGD:6480464 CTD
G Lcn2 lipocalin 2 GBrowse link multiple interactions ISO 3 11,511,402 11,514,747 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mmp2 matrix metallopeptidase 2 GBrowse link multiple interactions ISO 19 15,246,036 15,275,061 RGD:6480464 CTD
G Mmp2 matrix metallopeptidase 2 GBrowse link decreases activity ISO 19 15,246,036 15,275,061 RGD:6480464 CTD
G Mmp9 matrix metallopeptidase 9 GBrowse link multiple interactions ISO 3 155,985,473 155,993,433 RGD:6480464 CTD
G Mmp9 matrix metallopeptidase 9 GBrowse link decreases activity ISO 3 155,985,473 155,993,433 RGD:6480464 CTD
G Ncf2 neutrophil cytosolic factor 2 GBrowse link multiple interactions EXP 13 67,806,516 67,834,105 RGD:6480464 CTD
G Ncoa1 nuclear receptor coactivator 1 GBrowse link multiple interactions ISO 6 27,224,396 27,473,926 RGD:6480464 CTD
G Nos3 nitric oxide synthase 3, endothelial cell GBrowse link multiple interactions ISO 4 6,158,847 6,179,441 RGD:6480464 CTD
G Nos3 nitric oxide synthase 3, endothelial cell GBrowse link multiple interactions EXP 4 6,158,847 6,179,441 RGD:6480464 CTD
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 GBrowse link increases activity ISO 11 64,239,918 64,276,702 RGD:6480464 CTD
G Pdgfa platelet-derived growth factor alpha polypeptide GBrowse link multiple interactions ISO 12 16,151,045 16,172,412 RGD:6480464 CTD
G Pdgfb platelet-derived growth factor beta polypeptide GBrowse link multiple interactions ISO 7 118,244,385 118,262,021 RGD:6480464 CTD
G Pgr progesterone receptor GBrowse link decreases expression ISO 8 5,784,717 5,845,901 RGD:6480464 CTD
G Pgr progesterone receptor GBrowse link multiple interactions ISO 8 5,784,717 5,845,901 RGD:6480464 CTD
G Plg plasminogen GBrowse link increases expression ISO 1 42,782,464 42,825,149 RGD:6480464 CTD
G Prl prolactin GBrowse link multiple interactions ISO 17 44,699,101 44,709,162 RGD:6480464 CTD
G Prl prolactin GBrowse link increases expression ISO 17 44,699,101 44,709,162 RGD:6480464 CTD
G Prl prolactin GBrowse link multiple interactions ISO 17 44,699,101 44,709,162 RGD:6480464 CTD
G Prl prolactin GBrowse link multiple interactions ISO 17 44,699,101 44,709,162 RGD:6480464 CTD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link multiple interactions ISO 1 208,262,669 208,273,148 RGD:6480464 CTD
G Serpinc1 serpin peptidase inhibitor, clade C (antithrombin), member 1 GBrowse link increases expression ISO 13 76,548,456 76,562,724 RGD:6480464 CTD
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link increases expression ISO 12 20,931,996 20,942,374 RGD:6480464 CTD
G Sirt1 sirtuin 1 GBrowse link multiple interactions ISO 20 25,675,302 25,686,494 RGD:6480464 CTD
G Sod1 superoxide dismutase 1, soluble GBrowse link multiple interactions ISO 11 29,810,766 29,816,342 RGD:6480464 CTD
G Sod1 superoxide dismutase 1, soluble GBrowse link multiple interactions ISO 11 29,810,766 29,816,342 RGD:6480464 CTD
G Sod1 superoxide dismutase 1, soluble GBrowse link multiple interactions ISO 11 29,810,766 29,816,342 RGD:6480464 CTD
G Sod1 superoxide dismutase 1, soluble GBrowse link increases activity ISO 11 29,810,766 29,816,342 RGD:6480464 CTD
G Sod1 superoxide dismutase 1, soluble GBrowse link increases expression ISO 11 29,810,766 29,816,342 RGD:6480464 CTD
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link multiple interactions ISO 1 41,862,997 41,870,327 RGD:6480464 CTD
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link multiple interactions ISO 1 41,862,997 41,870,327 RGD:6480464 CTD
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link increases expression ISO 1 41,862,997 41,870,327 RGD:6480464 CTD
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link multiple interactions ISO 1 41,862,997 41,870,327 RGD:6480464 CTD
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link increases activity ISO 1 41,862,997 41,870,327 RGD:6480464 CTD
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link increases expression ISO 1 41,862,997 41,870,327 RGD:6480464 CTD
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link increases expression ISO 1 41,862,997 41,870,327 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Vcam1 vascular cell adhesion molecule 1 GBrowse link multiple interactions ISO 2 212,277,654 212,297,376 RGD:6480464 CTD
G Vdr vitamin D (1,25- dihydroxyvitamin D3) receptor GBrowse link multiple interactions ISO 7 136,567,614 136,617,280 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link increases expression ISO 9 10,520,730 10,536,071 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link multiple interactions ISO 9 10,520,730 10,536,071 RGD:6480464 CTD
G Wnt5a wingless-type MMTV integration site family, member 5A GBrowse link multiple interactions ISO 16 3,782,025 3,799,625 RGD:6480464 CTD
G Wnt5a wingless-type MMTV integration site family, member 5A GBrowse link increases expression ISO 16 3,782,025 3,799,625 RGD:6480464 CTD
G Zfp36 zinc finger protein 36 GBrowse link increases expression ISO 1 83,486,643 83,489,123 RGD:6480464 CTD
Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 492507
    role 482196
      application 245130
        pharmaceutical 173979
          drug 173776
            reproductive control drug 4812
              contraceptive drug 2924
                medroxyprogesterone 121
                  medroxyprogesterone acetate 116
Path 2
Term Annotations click to browse term
  CHEBI ontology 492507
    subatomic particle 491470
      composite particle 491470
        hadron 491470
          baryon 491470
            nucleon 491470
              atomic nucleus 491470
                atom 491470
                  main group element atom 461139
                    p-block element atom 458635
                      carbon group element atom 410624
                        carbon atom 407181
                          organic molecular entity 407174
                            organic group 167657
                              organic divalent group 166492
                                organodiyl group 166492
                                  carbonyl group 166182
                                    carbonyl compound 166182
                                      ketone 31427
                                        oxo steroid 13479
                                          3-oxo steroid 11984
                                            3-oxo Delta(4)-steroid 2529
                                              medroxyprogesterone 121
                                                medroxyprogesterone acetate 116
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