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Term:(6S)-5-formyltetrahydrofolic acid
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Accession:CHEBI:63606 term browser browse the term
Definition:The pharmacologically active (6S)-stereoisomer of 5-formyltetrahydrofolic acid.
Synonyms:exact_synonym: N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid
 related_synonym: (6S)-5-Formyl-5,6,7,8-tetrahydrofolic acid;   (6S)-Folinic acid;   (6S)-Leucovorin;   (S)-Leucovorin;   C20H23N7O7;   Citrovorum factor;   InChI=1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32)/t12-,13-/m0/s1;   InChIKey=VVIAGPKUTFNRDU-STQMWFEESA-N;   L-Folinic acid;   Levofolene;   Levofolinic acid;   N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid;   [H]C(=O)N1[C@@H](CNc2ccc(cc2)C(=O)N[C@@H](CCC(O)=O)C(O)=O)CNc2nc(N)[nH]c(=O)c12;   levoleucovorin
 xref_casrn: 68538-85-2
 xref: ChEMBL:1348760 "ChEMBL COMPOUND";   ChemIDplus:68538-85-2 "CAS Registry Number";   CiteXplore:11135086 "PubMed citation";   CiteXplore:11748463 "PubMed citation";   CiteXplore:12427152 "PubMed citation";   CiteXplore:18343754 "PubMed citation";   CiteXplore:18593999 "PubMed citation";   CiteXplore:19712610 "PubMed citation";   CiteXplore:20204366 "PubMed citation";   CiteXplore:20399639 "PubMed citation";   CiteXplore:21239357 "PubMed citation";   CiteXplore:21907007 "PubMed citation";   CiteXplore:22055112 "PubMed citation";   CiteXplore:7777248 "PubMed citation";   CiteXplore:8404828 "PubMed citation";   PDBeChem:FOZ "PDBeChem";   Reaxys:101690 "Reaxys Registry Number"
 cyclic_relationship: is_conjugate_acid_of CHEBI:57457


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  CHEBI ontology 501881
    role 491510
      biological role 489686
        biochemical role 195456
          metabolite 176736
            (6S)-5-formyltetrahydrofolic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 501881
    subatomic particle 500845
      composite particle 500845
        hadron 500845
          baryon 500845
            nucleon 500845
              atomic nucleus 500845
                atom 500845
                  main group element atom 470301
                    p-block element atom 467779
                      carbon group element atom 419149
                        carbon atom 415667
                          organic molecular entity 415660
                            organic group 171184
                              organic divalent group 169999
                                organodiyl group 169999
                                  carbonyl group 169689
                                    carbonyl compound 169689
                                      carboxylic acid 122651
                                        amino acid 50207
                                          modified amino acid 8623
                                            glutamic acid derivative 3557
                                              folic acids 3536
                                                tetrahydrofolic acid 55
                                                  formyltetrahydrofolic acid 40
                                                    5-formyltetrahydrofolic acid 39
                                                      (6S)-5-formyltetrahydrofolic acid 0
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