ONTOLOGY REPORT - ANNOTATIONS
| Term: | ketoprofen |
|
| Accession: | CHEBI:6128
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browse the term
|
| Definition: | A benzophenone that has formula C16H14O3. |
| Synonyms: | exact_synonym: | 2-(3-benzoylphenyl)propanoic acid |
| | related_synonym: | 2-(3-Benzoylphenyl)propionic acid; 3-Benzoyl-alpha-methylbenzeneacetic acid; 3-Benzoylhydratropic acid; C16H14O3; CC(C(O)=O)c1cccc(c1)C(=O)c1ccccc1; InChI=1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19); InChIKey=DKYWVDODHFEZIM-UHFFFAOYSA-N; L'Acide (benzoyl-3-phenyl)-2-propionique; Orudis (TN); m-Benzoylhydratropic acid |
| | xref_casrn: | 22071-15-4 |
| | xref: | ChEMBL:116591 "ChEMBL COMPOUND"; ChemIDplus:22071-15-4 "CAS Registry Number"; DrugBank:DB01009 "DrugBank"; KEGG COMPOUND:22071-15-4 "CAS Registry Number"; KEGG COMPOUND:C01716 "KEGG COMPOUND"; KEGG DRUG:D00132 "KEGG DRUG" |
| | xref_mesh: | MESH:D007660 |
| | xref: | NIST Chemistry WebBook:22071-15-4 "CAS Registry Number"; Wikipedia:Ketoprofen "Wikipedia" |
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ketoprofen
|
| G |
Alb |
albumin |
|
affects binding |
ISO |
14 |
19,126,935 |
19,142,214 |
RGD:6480464 |
CTD |
| G |
Alb |
albumin |
|
affects binding |
ISO |
14 |
19,126,935 |
19,142,214 |
RGD:6480464 |
CTD |
| G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
|
increases expression |
ISO |
8 |
82,724,429 |
82,762,848 |
RGD:6480464 |
CTD |
| G |
Gclm |
glutamate cysteine ligase, modifier subunit |
|
increases expression |
ISO |
2 |
218,895,434 |
218,915,491 |
RGD:6480464 |
CTD |
| G |
Il10 |
interleukin 10 |
|
multiple interactions |
ISO |
13 |
43,953,900 |
43,957,766 |
RGD:6480464 |
CTD |
| G |
Il6 |
interleukin 6 |
|
multiple interactions |
ISO |
4 |
456,799 |
461,376 |
RGD:6480464 |
CTD |
| G |
Mpo |
myeloperoxidase |
|
multiple interactions |
EXP |
10 |
76,085,872 |
76,097,012 |
RGD:6480464 |
CTD |
| G |
Mpo |
myeloperoxidase |
|
increases expression |
EXP |
10 |
76,085,872 |
76,097,012 |
RGD:6480464 |
CTD |
| G |
Ngfr |
nerve growth factor receptor |
|
increases expression |
ISO |
10 |
84,262,804 |
84,281,006 |
RGD:6480464 |
CTD |
| G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
|
multiple interactions |
ISO |
13 |
64,427,288 |
64,432,978 |
RGD:6480464 |
CTD |
| G |
Ren |
renin |
|
multiple interactions |
ISO |
13 |
46,262,936 |
46,275,213 |
RGD:6480464 |
CTD |
| G |
Sell |
selectin L |
|
decreases expression |
ISO |
13 |
79,827,342 |
79,845,296 |
RGD:6480464 |
CTD |
| G |
Slc22a1 |
solute carrier family 22 (organic cation transporter), member 1 |
|
decreases activity |
ISO |
1 |
42,351,239 |
42,378,295 |
RGD:6480464 |
CTD |
| G |
Slc22a6 |
solute carrier family 22 (organic anion transporter), member 6 |
|
decreases activity |
ISO |
1 |
211,294,178 |
211,302,398 |
RGD:6480464 |
CTD |
| G |
Slc22a6 |
solute carrier family 22 (organic anion transporter), member 6 |
|
increases uptake |
ISO |
1 |
211,294,178 |
211,302,398 |
RGD:6480464 |
CTD |
| G |
Slc22a7 |
solute carrier family 22 (organic anion transporter), member 7 |
|
decreases activity |
ISO |
9 |
9,934,309 |
9,940,107 |
RGD:6480464 |
CTD |
| G |
Slco1a1 |
solute carrier organic anion transporter family, member 1a1 |
|
multiple interactions |
EXP |
|
|
|
RGD:6480464 |
CTD |
| G |
Slco1a1 |
solute carrier organic anion transporter family, member 1a1 |
|
decreases activity |
EXP |
|
|
|
RGD:6480464 |
CTD |
| G |
Slco2a1 |
solute carrier organic anion transporter family, member 2a1 |
|
multiple interactions |
ISO |
8 |
108,012,829 |
108,098,561 |
RGD:6480464 |
CTD |
| G |
Tnf |
tumor necrosis factor |
|
multiple interactions |
ISO |
20 |
3,661,000 |
3,663,618 |
RGD:6480464 |
CTD |
| G |
Ugt1a1 |
UDP glucuronosyltransferase 1 family, polypeptide A1 |
|
decreases activity |
ISO |
9 |
87,091,241 |
87,098,362 |
RGD:6480464 |
CTD |
| G |
Ugt1a1 |
UDP glucuronosyltransferase 1 family, polypeptide A1 |
|
increases glucuronidation |
ISO |
9 |
87,091,241 |
87,098,362 |
RGD:6480464 |
CTD |
| G |
Ugt1a2 |
UDP glucuronosyltransferase 1 family, polypeptide A2 |
|
increases glucuronidation |
ISO |
9 |
87,081,132 |
87,098,362 |
RGD:6480464 |
CTD |
| G |
Ugt1a2 |
UDP glucuronosyltransferase 1 family, polypeptide A2 |
|
increases glucuronidation |
ISO |
9 |
87,081,132 |
87,098,362 |
RGD:6480464 |
CTD |
| G |
Ugt1a6 |
UDP glucuronosyltransferase 1 family, polypeptide A6 |
|
increases glucuronidation |
ISO |
9 |
87,037,154 |
87,098,362 |
RGD:6480464 |
CTD |
| G |
Ugt1a6 |
UDP glucuronosyltransferase 1 family, polypeptide A6 |
|
affects metabolic processing |
EXP |
9 |
87,037,154 |
87,098,362 |
RGD:6480464 |
CTD |
| G |
Ugt1a8 |
UDP glycosyltransferase 1 family, polypeptide A8 |
|
increases glucuronidation |
ISO |
9 |
87,017,029 |
87,098,362 |
RGD:6480464 |
CTD |
| G |
Ugt1a8 |
UDP glycosyltransferase 1 family, polypeptide A8 |
|
increases glucuronidation |
ISO |
9 |
87,017,029 |
87,098,362 |
RGD:6480464 |
CTD |
| G |
Ugt1a9 |
UDP glucuronosyltransferase 1 family, polypeptide A9 |
|
increases glucuronidation |
ISO |
9 |
86,986,915 |
87,098,362 |
RGD:6480464 |
CTD |
| G |
Ugt1a9 |
UDP glucuronosyltransferase 1 family, polypeptide A9 |
|
increases glucuronidation |
ISO |
9 |
86,986,915 |
87,098,362 |
RGD:6480464 |
CTD |
| G |
Ugt2b17 |
UDP glucuronosyltransferase 2 family, polypeptide B17 |
|
increases glucuronidation |
ISO |
14 |
22,639,182 |
22,650,931 |
RGD:6480464 |
CTD |
| G |
Ugt2b7 |
UDP glucuronosyltransferase 2 family, polypeptide B7 |
|
multiple interactions |
ISO |
14 |
22,499,152 |
22,522,842 |
RGD:6480464 |
CTD |
| G |
Ugt2b7 |
UDP glucuronosyltransferase 2 family, polypeptide B7 |
|
increases glucuronidation |
ISO |
14 |
22,499,152 |
22,522,842 |
RGD:6480464 |
CTD |
| G |
Ugt2b7 |
UDP glucuronosyltransferase 2 family, polypeptide B7 |
|
increases glucuronidation |
ISO |
14 |
22,499,152 |
22,522,842 |
RGD:6480464 |
CTD |
| G |
Ugt2b7 |
UDP glucuronosyltransferase 2 family, polypeptide B7 |
|
increases glucuronidation |
ISO |
14 |
22,499,152 |
22,522,842 |
RGD:6480464 |
CTD |
| G |
Ugt2b7 |
UDP glucuronosyltransferase 2 family, polypeptide B7 |
|
increases glucuronidation |
ISO |
14 |
22,499,152 |
22,522,842 |
RGD:6480464 |
CTD |
| G |
Ugt2b7 |
UDP glucuronosyltransferase 2 family, polypeptide B7 |
|
increases glucuronidation |
ISO |
14 |
22,499,152 |
22,522,842 |
RGD:6480464 |
CTD |
| G |
UST4r |
integral membrane transport protein UST4r |
|
increases uptake |
ISO |
1 |
210,618,706 |
210,688,125 |
RGD:6480464 |
CTD |
| G |
UST4r |
integral membrane transport protein UST4r |
|
decreases activity |
ISO |
1 |
210,618,706 |
210,688,125 |
RGD:6480464 |
CTD |
Term paths to the root
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