ONTOLOGY REPORT - ANNOTATIONS


Term:hyperforin
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Accession:CHEBI:5834 term browser browse the term
Definition:A sesquarterpenoid that has formula C35H52O4.
Synonyms:exact_synonym: (1R,5S,6R,7S)-4-hydroxy-6-methyl-1,3,7-tris(3-methylbut-2-en-1-yl)-6-(4-methylpent-3-en-1-yl)-5-(2-methylpropanoyl)bicyclo[3.3.1]non-3-ene-2,9-dione
 related_synonym: (1R,5S,6R,7S)-4-hydroxy-5-isobutyryl-6-methyl-1,3,7-tris(3-methylbut-2-en-1-yl)-6-(4-methylpent-3-en-1-yl)bicyclo[3.3.1]non-3-ene-2,9-dione;   C35H52O4;   CC(C)C(=O)[C@]12C(=O)[C@](CC=C(C)C)(C[C@H](CC=C(C)C)[C@@]1(C)CCC=C(C)C)C(=O)C(CC=C(C)C)=C2O;   InChI=1S/C35H52O4/c1-22(2)13-12-19-33(11)27(16-14-23(3)4)21-34(20-18-25(7)8)30(37)28(17-15-24(5)6)31(38)35(33,32(34)39)29(36)26(9)10/h13-15,18,26-27,38H,12,16-17,19-21H2,1-11H3/t27-,33+,34+,35-/m0/s1;   InChIKey=IWBJJCOKGLUQIZ-HQKKAZOISA-N;   hiperforina;   hyperforine
 xref_casrn: 11079-53-1
 xref: Beilstein:6785663 "Beilstein Registry Number";   ChEMBL:799561 "ChEMBL COMPOUND";   ChemIDplus:11079-53-1 "CAS Registry Number";   DrugBank:DB01892 "DrugBank";   KEGG COMPOUND:11079-53-1 "CAS Registry Number";   KEGG COMPOUND:C07608 "KEGG COMPOUND"
 xref_mesh: MESH:C001654


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Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link multiple interactions ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link increases expression ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 GBrowse link multiple interactions ISO 8 61,462,207 61,468,237 RGD:6480464 CTD
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 GBrowse link decreases activity ISO 8 61,462,207 61,468,237 RGD:6480464 CTD
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 GBrowse link increases expression ISO 3 161,542,131 161,553,801 RGD:6480464 CTD
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 GBrowse link multiple interactions ISO 1 243,281,320 243,320,945 RGD:6480464 CTD
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 GBrowse link increases expression ISO 1 243,281,320 243,320,945 RGD:6480464 CTD
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 GBrowse link multiple interactions ISO 1 243,281,320 243,320,945 RGD:6480464 CTD
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 GBrowse link increases expression ISO 1 243,281,320 243,320,945 RGD:6480464 CTD
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 GBrowse link decreases activity ISO 12 9,517,016 9,541,000 RGD:6480464 CTD
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 GBrowse link multiple interactions ISO 12 9,517,016 9,541,000 RGD:6480464 CTD
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 GBrowse link increases expression ISO 12 9,517,016 9,541,000 RGD:6480464 CTD
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 GBrowse link increases expression ISO 12 9,517,016 9,541,000 RGD:6480464 CTD
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 GBrowse link increases expression ISO 12 9,517,016 9,541,000 RGD:6480464 CTD
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 GBrowse link increases expression ISO 12 9,517,016 9,541,000 RGD:6480464 CTD
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 GBrowse link increases expression ISO 12 9,517,016 9,541,000 RGD:6480464 CTD
G Icam1 intercellular adhesion molecule 1 GBrowse link increases expression ISO 8 20,040,177 20,051,939 RGD:6480464 CTD
G Jun jun proto-oncogene GBrowse link multiple interactions ISO 5 115,358,166 115,361,259 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link increases phosphorylation ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link increases phosphorylation ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 GBrowse link increases activity ISO 11 64,239,918 64,276,702 RGD:6480464 CTD
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 GBrowse link multiple interactions ISO 11 64,239,918 64,276,702 RGD:6480464 CTD
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 GBrowse link multiple interactions ISO 11 64,239,918 64,276,702 RGD:6480464 CTD
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 GBrowse link multiple interactions ISO 11 64,239,918 64,276,702 RGD:6480464 CTD

Term paths to the root
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  CHEBI ontology 501881
    chemical entity 501881
      atom 500845
        nonmetal atom 459609
          carbon atom 415667
            organic molecular entity 415660
              isoprenoid 15773
                terpenoid 15420
                  sesquarterpenoid 24
                    hyperforin 24
Path 2
Term Annotations click to browse term
  CHEBI ontology 501881
    subatomic particle 500845
      composite particle 500845
        hadron 500845
          baryon 500845
            nucleon 500845
              atomic nucleus 500845
                atom 500845
                  main group element atom 470301
                    p-block element atom 467779
                      carbon group element atom 419149
                        carbon atom 415667
                          organic molecular entity 415660
                            organic group 171184
                              organic divalent group 169999
                                organodiyl group 169999
                                  carbonyl group 169689
                                    carbonyl compound 169689
                                      ketone 31633
                                        cyclic ketone 13385
                                          alicyclic ketone 880
                                            cyclic terpene ketone 40
                                              hyperforin 24
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