ONTOLOGY REPORT - ANNOTATIONS

Term:razoxane
go back to main search page
Accession:CHEBI:50225 term browser browse the term
Definition:A N-alkylpiperazine that has formula C11H16N4O4.
Synonyms:exact_synonym: 4,4'-propane-1,2-diyldipiperazine-2,6-dione
 related_synonym: (+,-)-1,2-Bis(3,5-dioxopiperazine-1-yl)propane;   C11H16N4O4;   CC(CN1CC(=O)NC(=O)C1)N1CC(=O)NC(=O)C1;   InChI=1S/C11H16N4O4/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19);   InChIKey=BMKDZUISNHGIBY-UHFFFAOYSA-N;   razoxana;   razoxanum
 xref_casrn: 21416-87-5
 xref: ChEMBL:554214 "ChEMBL COMPOUND";   ChemIDplus:21416-87-5 "CAS Registry Number"
 xref_mesh: MESH:D011929
 xref: Patent:DE1941564 "Patent"

  • Rat
  • Mouse
  • Human
  • All
  • show annotations for term's descendants
  •     Sort by:
razoxane term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link multiple interactions ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link increases expression ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link increases activity EXP 6 137,640,482 137,657,552 RGD:6480464 CTD
G Ank3 ankyrin 3, node of Ranvier (ankyrin G) GBrowse link decreases expression EXP 20 19,328,684 19,828,196 RGD:6480464 CTD
G Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 GBrowse link multiple interactions EXP 12 35,266,600 35,316,237 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link multiple interactions ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link increases expression ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bnip1 BCL2/adenovirus E1B interacting protein 1 GBrowse link multiple interactions ISO 10 16,648,619 16,660,896 RGD:6480464 CTD
G Bnip1 BCL2/adenovirus E1B interacting protein 1 GBrowse link increases expression ISO 10 16,648,619 16,660,896 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp7 caspase 7 GBrowse link increases activity ISO 1 262,689,300 262,721,591 RGD:6480464 CTD
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link multiple interactions EXP 10 70,256,263 70,258,061 RGD:6480464 CTD
G Ccl20 chemokine (C-C motif) ligand 20 GBrowse link multiple interactions EXP 9 82,440,965 82,443,542 RGD:6480464 CTD
G Cd14 CD14 molecule GBrowse link multiple interactions EXP 18 29,374,593 29,376,190 RGD:6480464 CTD
G Clu clusterin GBrowse link multiple interactions ISO 15 45,365,779 45,405,314 RGD:6480464 CTD
G Clu clusterin GBrowse link decreases expression ISO 15 45,365,779 45,405,314 RGD:6480464 CTD
G Egr1 early growth response 1 GBrowse link multiple interactions ISO 18 27,343,919 27,346,117 RGD:6480464 CTD
G Egr1 early growth response 1 GBrowse link decreases expression ISO 18 27,343,919 27,346,117 RGD:6480464 CTD
G Ftl ferritin, light polypeptide GBrowse link multiple interactions ISO 1 95,929,248 95,931,092 RGD:6480464 CTD
G Ftmt ferritin mitochondrial GBrowse link multiple interactions ISO 18 47,678,332 47,679,581 RGD:6480464 CTD
G Gabra3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 GBrowse link decreases expression EXP X 158,405,509 158,633,501 RGD:6480464 CTD
G Gabra4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 GBrowse link decreases expression EXP 14 39,047,461 39,122,531 RGD:6480464 CTD
G H2afx H2A histone family, member X GBrowse link multiple interactions EXP 8 47,312,609 47,313,938 RGD:6480464 CTD
G Hif1a hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) GBrowse link multiple interactions ISO 6 96,419,024 96,463,891 RGD:6480464 CTD
G Hif1a hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) GBrowse link increases activity ISO 6 96,419,024 96,463,891 RGD:6480464 CTD
G Hmox1 heme oxygenase (decycling) 1 GBrowse link multiple interactions ISO 19 13,963,139 13,969,960 RGD:6480464 CTD
G Hmox1 heme oxygenase (decycling) 1 GBrowse link increases expression ISO 19 13,963,139 13,969,960 RGD:6480464 CTD
G Jph2 junctophilin 2 GBrowse link multiple interactions EXP 3 154,223,264 154,289,256 RGD:6480464 CTD
G Jun jun proto-oncogene GBrowse link affects expression ISO 5 115,358,166 115,361,259 RGD:6480464 CTD
G Klhl41 kelch-like family member 41 GBrowse link multiple interactions EXP 3 51,816,016 51,829,140 RGD:6480464 CTD
G Lepr leptin receptor GBrowse link decreases expression EXP 5 122,320,075 122,503,449 RGD:6480464 CTD
G Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 GBrowse link multiple interactions EXP 1 168,601,460 168,622,234 RGD:6480464 CTD
G Map1a microtubule-associated protein 1A GBrowse link decreases expression EXP 3 108,097,119 108,111,060 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions EXP 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk14 mitogen activated protein kinase 14 GBrowse link multiple interactions EXP 20 6,939,249 7,000,378 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions EXP 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mapk8 mitogen-activated protein kinase 8 GBrowse link affects activity ISO 16 8,925,133 9,004,897 RGD:6480464 CTD
G Mmp2 matrix metallopeptidase 2 GBrowse link multiple interactions EXP 19 15,246,036 15,275,061 RGD:6480464 CTD
G Mmp2 matrix metallopeptidase 2 GBrowse link multiple interactions EXP 19 15,246,036 15,275,061 RGD:6480464 CTD
G Mmp9 matrix metallopeptidase 9 GBrowse link multiple interactions EXP 3 155,985,473 155,993,433 RGD:6480464 CTD
G Msn moesin GBrowse link decreases expression EXP X 83,716,068 83,784,214 RGD:6480464 CTD
G Myh3 myosin, heavy chain 3, skeletal muscle, embryonic GBrowse link decreases expression EXP 10 53,776,858 53,800,677 RGD:6480464 CTD
G Myl1 myosin, light chain 1 GBrowse link multiple interactions EXP 9 65,717,097 65,737,576 RGD:6480464 CTD
G Nol3 nucleolar protein 3 (apoptosis repressor with CARD domain) GBrowse link multiple interactions EXP 19 35,094,345 35,096,012 RGD:6480464 CTD
G Nox1 NADPH oxidase 1 multiple interactions EXP RGD:6480464 CTD
G Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 GBrowse link multiple interactions EXP 4 166,747,228 166,769,340 RGD:6480464 CTD
G Pfkp phosphofructokinase, platelet GBrowse link multiple interactions EXP 17 74,760,912 74,823,046 RGD:6480464 CTD
G Postn periostin, osteoblast specific factor GBrowse link multiple interactions EXP 2 143,537,099 143,568,341 RGD:6480464 CTD
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A GBrowse link multiple interactions EXP 7 46,876,552 46,986,022 RGD:6480464 CTD
G Ppp1r2 protein phosphatase 1, regulatory (inhibitor) subunit 2 GBrowse link multiple interactions EXP 11 71,319,294 71,342,716 RGD:6480464 CTD
G Ppp2ca protein phosphatase 2, catalytic subunit, alpha isozyme GBrowse link multiple interactions EXP 10 37,621,256 37,641,008 RGD:6480464 CTD
G Ryr2 ryanodine receptor 2, cardiac GBrowse link multiple interactions EXP 17 68,959,042 69,544,816 RGD:6480464 CTD
G Scn1a sodium channel, voltage-gated, type I, alpha GBrowse link multiple interactions EXP 3 48,238,528 48,364,143 RGD:6480464 CTD
G Timp1 TIMP metallopeptidase inhibitor 1 GBrowse link multiple interactions EXP X 12,542,496 12,547,094 RGD:6480464 CTD
G Top2a topoisomerase (DNA) II alpha GBrowse link affects binding ISO 10 87,771,337 87,800,960 RGD:6480464 CTD
G Top2b topoisomerase (DNA) II beta affects binding ISO RGD:6480464 CTD
G Top2b topoisomerase (DNA) II beta multiple interactions EXP RGD:6480464 CTD
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 492574
    chemical entity 492574
      atom 491537
        nonmetal atom 450591
          nitrogen atom 170096
            nitrogen molecular entity 170096
              organonitrogen compound 150531
                organonitrogen heterocyclic compound 78768
                  piperazines 2997
                    N-alkylpiperazine 2258
                      razoxane 59
                        (+)-dexrazoxane + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 492574
    subatomic particle 491537
      composite particle 491537
        hadron 491537
          baryon 491537
            nucleon 491537
              atomic nucleus 491537
                atom 491537
                  main group element atom 461203
                    p-block element atom 458699
                      carbon group element atom 410677
                        carbon atom 407233
                          organic molecular entity 407226
                            organic molecule 359465
                              organic cyclic compound 298342
                                organic heterocyclic compound 154273
                                  organic heteromonocyclic compound 58845
                                    piperazines 2997
                                      N-alkylpiperazine 2258
                                        razoxane 59
                                          (+)-dexrazoxane + 0
paths to the root

Contact Us |  About Us |  Jobs at RGD