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Term:gefitinib
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Accession:CHEBI:49668 term browser browse the term
Definition:A quinazoline that has formula C22H24ClFN4O3.
Synonyms:exact_synonym: N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
 related_synonym: 4-(3'-chloro-4'-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline;   C22H24ClFN4O3;   COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1;   InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27);   InChIKey=XGALLCVXEZPNRQ-UHFFFAOYSA-N;   Iressa;   N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine;   ZD 1839
 alt_id: CHEBI:38917;   CHEBI:49667
 xref_casrn: 184475-35-2
 xref: ChEMBL:188232 "ChEMBL COMPOUND";   ChemIDplus:184475-35-2 "CAS Registry Number";   DrugBank:DB00317 "DrugBank"
 xref_mesh: MESH:C419708
 xref: PDBeChem:IRE "PDBeChem";   Wikipedia:Gefitinib "Wikipedia"

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gefitinib term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 decreases activity ISO RGD:6480464 CTD
G Abcg2 ATP-binding cassette, subfamily G (WHITE), member 2 GBrowse link multiple interactions ISO 4 87,502,584 87,560,017 RGD:6480464 CTD
G Adora1 adenosine A1 receptor GBrowse link decreases expression ISO 13 47,160,292 47,192,804 RGD:6480464 CTD
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link multiple interactions ISO 6 137,640,482 137,657,552 RGD:6480464 CTD
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link multiple interactions ISO 6 137,640,482 137,657,552 RGD:6480464 CTD
G Areg amphiregulin GBrowse link affects response to substance ISO 14 18,466,313 18,475,571 RGD:6480464 CTD
G Areg amphiregulin GBrowse link decreases response to substance ISO 14 18,466,313 18,475,571 RGD:6480464 CTD
G Areg amphiregulin GBrowse link multiple interactions ISO 14 18,466,313 18,475,571 RGD:6480464 CTD
G Areg amphiregulin GBrowse link decreases response to substance ISO 14 18,466,313 18,475,571 RGD:6480464 CTD
G Atg5 autophagy related 5 GBrowse link increases expression ISO 20 48,273,977 48,366,743 RGD:6480464 CTD
G Atg7 autophagy related 7 GBrowse link increases expression ISO 4 150,814,706 150,992,704 RGD:6480464 CTD
G Aurka aurora kinase A GBrowse link decreases response to substance ISO 3 163,270,479 163,284,506 RGD:6480464 CTD
G Aurka aurora kinase A GBrowse link multiple interactions ISO 3 163,270,479 163,284,506 RGD:6480464 CTD
G Aven apoptosis, caspase activation inhibitor GBrowse link affects response to substance ISO 3 98,404,029 98,475,755 RGD:6480464 CTD
G Bcl2l11 BCL2-like 11 (apoptosis facilitator) GBrowse link increases response to substance ISO 3 115,692,323 115,722,701 RGD:6480464 CTD
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO RGD:6480464 CTD
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO RGD:6480464 CTD
G Cav1 caveolin 1, caveolae protein GBrowse link increases expression ISO 4 42,956,102 42,989,057 RGD:6480464 CTD
G Ccnd1 cyclin D1 GBrowse link decreases expression ISO 1 205,357,235 205,366,757 RGD:6480464 CTD
G Ccnd1 cyclin D1 GBrowse link decreases expression ISO 1 205,357,235 205,366,757 RGD:6480464 CTD
G Ccnd3 cyclin D3 decreases expression ISO RGD:6480464 CTD
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link increases expression ISO 20 7,376,325 7,386,778 RGD:6480464 CTD
G Cdkn1b cyclin-dependent kinase inhibitor 1B GBrowse link multiple interactions ISO 4 171,841,705 171,846,506 RGD:6480464 CTD
G Cdkn1b cyclin-dependent kinase inhibitor 1B GBrowse link decreases expression ISO 4 171,841,705 171,846,506 RGD:6480464 CTD
G Cdkn1b cyclin-dependent kinase inhibitor 1B GBrowse link increases expression ISO 4 171,841,705 171,846,506 RGD:6480464 CTD
G Cdkn1b cyclin-dependent kinase inhibitor 1B GBrowse link increases expression ISO 4 171,841,705 171,846,506 RGD:6480464 CTD
G Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) GBrowse link increases expression ISO 5 108,939,669 108,945,293 RGD:6480464 CTD
G Cgrrf1 cell growth regulator with ring finger domain 1 GBrowse link increases expression ISO 15 22,683,387 22,703,833 RGD:6480464 CTD
G Cldn2 claudin 2 GBrowse link multiple interactions ISO X 127,538,685 127,549,019 RGD:6480464 CTD
G Col4a3bp collagen, type IV, alpha 3 (Goodpasture antigen) binding protein GBrowse link affects response to substance ISO 2 27,012,330 27,117,057 RGD:6480464 CTD
G Coro1c coronin, actin binding protein 1C GBrowse link affects response to substance ISO 12 43,747,188 43,819,356 RGD:6480464 CTD
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 GBrowse link affects metabolic processing ISO 7 120,778,783 120,783,140 RGD:6480464 CTD
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 GBrowse link affects metabolic processing ISO 7 120,742,273 120,752,274 RGD:6480464 CTD
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 GBrowse link decreases expression ISO 1 82,191,741 82,204,629 RGD:6480464 CTD
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 GBrowse link affects metabolic processing ISO 12 9,517,016 9,541,000 RGD:6480464 CTD
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 GBrowse link affects metabolic processing ISO 12 17,164,384 17,204,589 RGD:6480464 CTD
G Dusp3 dual specificity phosphatase 3 GBrowse link affects response to substance ISO 10 91,031,206 91,044,858 RGD:6480464 CTD
G Dusp9 dual specificity phosphatase 9 GBrowse link decreases expression ISO X 159,538,012 159,541,937 RGD:6480464 CTD
G E2f1 E2F transcription factor 1 GBrowse link decreases expression ISO 3 145,032,489 145,043,729 RGD:6480464 CTD
G E2f1 E2F transcription factor 1 GBrowse link decreases expression ISO 3 145,032,489 145,043,729 RGD:6480464 CTD
G E2f1 E2F transcription factor 1 GBrowse link decreases expression ISO 3 145,032,489 145,043,729 RGD:6480464 CTD
G Ednrb endothelin receptor type B GBrowse link multiple interactions ISO 15 87,893,141 87,898,700 RGD:6480464 CTD
G Egf epidermal growth factor GBrowse link multiple interactions ISO 2 227,103,900 227,195,062 RGD:6480464 CTD
G Egf epidermal growth factor GBrowse link multiple interactions ISO 2 227,103,900 227,195,062 RGD:6480464 CTD
G Egf epidermal growth factor GBrowse link multiple interactions ISO 2 227,103,900 227,195,062 RGD:6480464 CTD
G Egf epidermal growth factor GBrowse link multiple interactions ISO 2 227,103,900 227,195,062 RGD:6480464 CTD
G Egf epidermal growth factor GBrowse link multiple interactions ISO 2 227,103,900 227,195,062 RGD:6480464 CTD
G Egf epidermal growth factor GBrowse link multiple interactions ISO 2 227,103,900 227,195,062 RGD:6480464 CTD
G Egf epidermal growth factor GBrowse link multiple interactions ISO 2 227,103,900 227,195,062 RGD:6480464 CTD
G Egf epidermal growth factor GBrowse link multiple interactions ISO 2 227,103,900 227,195,062 RGD:6480464 CTD
G Egf epidermal growth factor GBrowse link multiple interactions ISO 2 227,103,900 227,195,062 RGD:6480464 CTD
G Egf epidermal growth factor GBrowse link multiple interactions ISO 2 227,103,900 227,195,062 RGD:6480464 CTD
G Egf epidermal growth factor GBrowse link multiple interactions ISO 2 227,103,900 227,195,062 RGD:6480464 CTD
G Egf epidermal growth factor GBrowse link multiple interactions ISO 2 227,103,900 227,195,062 RGD:6480464 CTD
G Egf epidermal growth factor GBrowse link multiple interactions ISO 2 227,103,900 227,195,062 RGD:6480464 CTD
G Egf epidermal growth factor GBrowse link multiple interactions ISO 2 227,103,900 227,195,062 RGD:6480464 CTD
G Egf epidermal growth factor GBrowse link multiple interactions ISO 2 227,103,900 227,195,062 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link decreases response to substance ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link affects response to substance ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link increases response to substance ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link increases response to substance ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link affects response to substance ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link decreases response to substance ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link increases response to substance ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link multiple interactions ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link multiple interactions ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link multiple interactions ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link multiple interactions ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link multiple interactions ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link multiple interactions ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link multiple interactions ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link decreases activity ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link multiple interactions ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link decreases phosphorylation ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link decreases expression ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link multiple interactions ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link multiple interactions ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link decreases expression EXP 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link decreases phosphorylation EXP 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link affects response to substance ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link increases response to substance ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link decreases activity ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link decreases phosphorylation ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link affects response to substance ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link multiple interactions ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link decreases phosphorylation ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link affects response to substance ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link multiple interactions ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link decreases phosphorylation ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link decreases phosphorylation ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link affects response to substance ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link multiple interactions ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link affects response to substance ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link affects response to substance ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link decreases phosphorylation ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link multiple interactions ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Epor erythropoietin receptor GBrowse link increases expression ISO 8 21,061,310 21,065,886 RGD:6480464 CTD
G Eps15 epidermal growth factor receptor pathway substrate 15 GBrowse link increases expression ISO 5 130,639,805 130,739,014 RGD:6480464 CTD
G Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) GBrowse link multiple interactions ISO 10 87,219,157 87,242,919 RGD:6480464 CTD
G Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) GBrowse link decreases phosphorylation ISO 10 87,219,157 87,242,919 RGD:6480464 CTD
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 GBrowse link multiple interactions ISO 1 78,711,249 78,722,474 RGD:6480464 CTD
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 GBrowse link affects response to substance ISO 1 78,711,249 78,722,474 RGD:6480464 CTD
G Esr1 estrogen receptor 1 GBrowse link decreases phosphorylation ISO 1 35,523,680 35,759,891 RGD:6480464 CTD
G Esr2 estrogen receptor 2 (ER beta) GBrowse link increases expression ISO 6 98,691,167 98,775,299 RGD:6480464 CTD
G Fgf6 fibroblast growth factor 6 GBrowse link increases expression ISO 4 163,403,896 163,412,431 RGD:6480464 CTD
G Foxo3 forkhead box O3 GBrowse link increases response to substance ISO 20 46,171,784 46,262,818 RGD:6480464 CTD
G Foxo3 forkhead box O3 GBrowse link multiple interactions ISO 20 46,171,784 46,262,818 RGD:6480464 CTD
G Gadd45a growth arrest and DNA-damage-inducible, alpha GBrowse link increases expression ISO 4 96,649,941 96,652,243 RGD:6480464 CTD
G Gadd45g growth arrest and DNA-damage-inducible, gamma GBrowse link decreases expression ISO 17 19,230,896 19,232,641 RGD:6480464 CTD
G Gars glycyl-tRNA synthetase GBrowse link increases expression ISO 4 83,718,584 83,759,591 RGD:6480464 CTD
G Gclc glutamate-cysteine ligase, catalytic subunit GBrowse link affects response to substance ISO 8 82,724,429 82,762,848 RGD:6480464 CTD
G Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 GBrowse link decreases expression ISO 12 19,597,312 19,602,329 RGD:6480464 CTD
G Gnmt glycine N-methyltransferase GBrowse link multiple interactions ISO 9 10,127,092 10,130,444 RGD:6480464 CTD
G Gucy2d guanylate cyclase 2D, membrane (retina-specific) GBrowse link decreases expression ISO 10 56,012,236 56,027,290 RGD:6480464 CTD
G Hbegf heparin-binding EGF-like growth factor GBrowse link multiple interactions ISO 18 29,143,567 29,153,944 RGD:6480464 CTD
G Igf1r insulin-like growth factor 1 receptor GBrowse link multiple interactions ISO 1 122,704,976 122,990,007 RGD:6480464 CTD
G Igf1r insulin-like growth factor 1 receptor GBrowse link increases phosphorylation ISO 1 122,704,976 122,990,007 RGD:6480464 CTD
G Itgav integrin, alpha V GBrowse link multiple interactions ISO 3 66,953,403 67,029,774 RGD:6480464 CTD
G Itgb1 integrin, beta 1 GBrowse link multiple interactions ISO 19 58,600,095 58,647,531 RGD:6480464 CTD
G Kdr kinase insert domain receptor multiple interactions ISO RGD:6480464 CTD
G Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog GBrowse link affects response to substance ISO 4 182,869,242 182,895,106 RGD:6480464 CTD
G Lepr leptin receptor GBrowse link decreases expression ISO 5 122,320,075 122,503,449 RGD:6480464 CTD
G Lgals9 lectin, galactoside-binding, soluble, 9 GBrowse link multiple interactions ISO 10 65,129,006 65,152,052 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link decreases expression ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link decreases phosphorylation ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions EXP 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link increases phosphorylation ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link decreases phosphorylation ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link decreases expression ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link increases phosphorylation ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions EXP 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mapk8 mitogen-activated protein kinase 8 GBrowse link increases phosphorylation ISO 16 8,925,133 9,004,897 RGD:6480464 CTD
G Mdk midkine GBrowse link multiple interactions ISO 3 76,309,988 76,311,345 RGD:6480464 CTD
G Mlh1 mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) GBrowse link decreases expression ISO 8 115,616,396 115,653,471 RGD:6480464 CTD
G Mmp9 matrix metallopeptidase 9 GBrowse link multiple interactions ISO 3 155,985,473 155,993,433 RGD:6480464 CTD
G Mtor mechanistic target of rapamycin (serine/threonine kinase) GBrowse link decreases phosphorylation ISO 5 165,531,402 165,640,899 RGD:6480464 CTD
G Myc myelocytomatosis oncogene GBrowse link decreases expression ISO 7 98,953,142 98,958,060 RGD:6480464 CTD
G Ndufaf4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 GBrowse link multiple interactions ISO 5 39,939,787 39,944,959 RGD:6480464 CTD
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 GBrowse link decreases expression ISO 2 233,091,013 233,187,501 RGD:6480464 CTD
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha GBrowse link multiple interactions ISO 6 75,729,302 75,732,475 RGD:6480464 CTD
G Nptx2 neuronal pentraxin II GBrowse link decreases expression ISO 12 10,359,406 10,370,315 RGD:6480464 CTD
G Nrl neural retina leucine zipper GBrowse link decreases expression ISO 15 33,649,927 33,656,045 RGD:6480464 CTD
G Olr93 olfactory receptor 93 GBrowse link multiple interactions ISO 1 161,092,784 161,093,728 RGD:6480464 CTD
G Osmr oncostatin M receptor GBrowse link affects response to substance ISO 2 56,080,700 56,121,463 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link multiple interactions ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Pecam1 platelet/endothelial cell adhesion molecule 1 GBrowse link multiple interactions ISO 10 96,056,220 96,057,232 RGD:6480464 CTD
G Phlda2 pleckstrin homology-like domain, family A, member 2 GBrowse link affects response to substance ISO 1 203,878,093 203,879,038 RGD:6480464 CTD
G Plbd1 phospholipase B domain containing 1 GBrowse link affects response to substance ISO 4 173,611,465 173,667,759 RGD:6480464 CTD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link multiple interactions ISO 13 64,427,288 64,432,978 RGD:6480464 CTD
G Qsox1 quiescin Q6 sulfhydryl oxidase 1 GBrowse link increases expression ISO 13 70,739,793 70,777,526 RGD:6480464 CTD
G Rbm7 RNA binding motif protein 7 GBrowse link affects response to substance ISO 8 51,769,353 51,774,447 RGD:6480464 CTD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link multiple interactions ISO 1 208,262,669 208,273,148 RGD:6480464 CTD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link decreases response to substance ISO 1 208,262,669 208,273,148 RGD:6480464 CTD
G Rpa1 replication protein A1 GBrowse link increases expression ISO 10 62,613,169 62,656,565 RGD:6480464 CTD
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 GBrowse link decreases phosphorylation ISO 10 76,657,024 76,698,088 RGD:6480464 CTD
G Rrm1-ps1 ribonucleotide reductase M1, pseudogene 1 GBrowse link affects response to substance ISO 14 77,408,781 77,411,150 RGD:6480464 CTD
G S100a6 S100 calcium binding protein A6 GBrowse link multiple interactions ISO 2 182,895,080 182,896,305 RGD:6480464 CTD
G S100a8 S100 calcium binding protein A8 GBrowse link multiple interactions ISO 2 182,961,994 182,962,513 RGD:6480464 CTD
G Serpinf1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 GBrowse link multiple interactions ISO 10 62,713,441 62,739,444 RGD:6480464 CTD
G Sfn stratifin GBrowse link decreases expression ISO 5 151,475,395 151,479,996 RGD:6480464 CTD
G Slc10a3 solute carrier family 10 (sodium/bile acid cotransporter family), member 3 GBrowse link multiple interactions ISO X 160,234,831 160,238,637 RGD:6480464 CTD
G Snai2 snail family zinc finger 2 affects response to substance ISO RGD:6480464 CTD
G Stat3 signal transducer and activator of transcription 3 (acute-phase response factor) GBrowse link multiple interactions ISO 10 89,821,078 89,872,970 RGD:6480464 CTD
G Stat3 signal transducer and activator of transcription 3 (acute-phase response factor) GBrowse link multiple interactions ISO 10 89,821,078 89,872,970 RGD:6480464 CTD
G Stfa2l1 stefin A2-like 1 GBrowse link multiple interactions ISO 11 66,263,202 66,267,857 RGD:6480464 CTD
G Synpo synaptopodin GBrowse link multiple interactions ISO 18 56,552,991 56,573,981 RGD:6480464 CTD
G Tek TEK tyrosine kinase, endothelial GBrowse link multiple interactions ISO 5 115,047,195 115,196,172 RGD:6480464 CTD
G Tert telomerase reverse transcriptase GBrowse link decreases expression ISO 1 30,445,180 30,465,942 RGD:6480464 CTD
G Tgfa transforming growth factor alpha GBrowse link decreases response to substance ISO 4 120,355,649 120,437,772 RGD:6480464 CTD
G Tgfa transforming growth factor alpha GBrowse link multiple interactions ISO 4 120,355,649 120,437,772 RGD:6480464 CTD
G Tgfa transforming growth factor alpha GBrowse link multiple interactions ISO 4 120,355,649 120,437,772 RGD:6480464 CTD
G Tgfa transforming growth factor alpha GBrowse link multiple interactions ISO 4 120,355,649 120,437,772 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b GBrowse link decreases expression ISO 5 163,666,541 163,697,484 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link multiple interactions ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link affects response to substance ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Trim23 tripartite motif-containing 23 GBrowse link multiple interactions ISO 2 35,101,019 35,135,028 RGD:6480464 CTD
G Tyms thymidylate synthetase GBrowse link decreases expression ISO 9 112,604,912 112,617,706 RGD:6480464 CTD
G Tyms thymidylate synthetase GBrowse link multiple interactions ISO 9 112,604,912 112,617,706 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link multiple interactions ISO 9 10,520,730 10,536,071 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link decreases expression EXP 9 10,520,730 10,536,071 RGD:6480464 CTD
G Xrcc1 X-ray repair complementing defective repair in Chinese hamster cells 1 GBrowse link affects response to substance ISO 1 79,834,167 79,860,300 RGD:6480464 CTD
G Zc3h3 zinc finger CCCH type containing 3 GBrowse link multiple interactions ISO 7 113,714,123 113,813,124 RGD:6480464 CTD
G Zfp35 zinc finger protein 35 GBrowse link multiple interactions ISO 18 15,749,584 15,765,238 RGD:6480464 CTD
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 501881
    role 491510
      application 249674
        pharmaceutical 177241
          drug 177038
            antineoplastic agent 67607
              gefitinib 202
                linkable gefitinib analogue 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 501881
    subatomic particle 500845
      composite particle 500845
        hadron 500845
          baryon 500845
            nucleon 500845
              atomic nucleus 500845
                atom 500845
                  main group element atom 470301
                    p-block element atom 467779
                      carbon group element atom 419149
                        carbon atom 415667
                          organic molecular entity 415660
                            organic molecule 365810
                              organic cyclic compound 304492
                                organic heterocyclic compound 158510
                                  organic heteropolycyclic compound 97199
                                    organic heterobicyclic compound 59093
                                      quinazolines 465
                                        gefitinib 202
                                          linkable gefitinib analogue 0
paths to the root

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