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Term:enalapril
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Accession:CHEBI:4784 term browser browse the term
Definition:A dicarboxylic acid monoester that is ethyl 4-phenylbutanoate in which a hydrogen alpha to the carboxy group is substituted by the amino group of L-alanyl-L-proline (S-configuration).
Synonyms:exact_synonym: N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl-L-proline
 related_synonym: (S)-1-(N-(1-(ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline;   (S)-1-{(S)-2-[1-((S)-Ethoxycarbonyl)-3-phenyl-propylamino]-propionyl}-pyrrolidine-2-carboxylic acid;   1-(N-((S)-1-carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl ester;   C20H28N2O5;   CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O;   InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1;   InChIKey=GBXSMTUPTTWBMN-XIRDDKMYSA-N;   enalaprila;   enalaprilum
 alt_id: CHEBI:116847
 xref_casrn: 75847-73-3
 xref: Beilstein:3657467 "Beilstein Registry Number";   ChEMBL:10669559 "PubMed citation";   ChEMBL:116847 "ChEMBL COMPOUND";   ChemIDplus:75847-73-3 "CAS Registry Number";   DrugBank:DB00584 "DrugBank";   KEGG COMPOUND:75847-73-3 "CAS Registry Number";   KEGG COMPOUND:C06977 "KEGG COMPOUND";   KEGG DRUG:D07892 "KEGG DRUG"
 xref_mesh: MESH:D004656
 xref: Patent:EP12401 "Patent";   Patent:US4374829 "Patent";   Wikipedia:Enalapril "Wikipedia"

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Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Abcc4 ATP-binding cassette, subfamily C (CFTR/MRP), member 4 GBrowse link increases transport ISO 15 103,384,848 103,611,238 RGD:6480464 CTD
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 GBrowse link decreases activity ISO 10 95,361,338 95,381,455 RGD:6480464 CTD
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 GBrowse link multiple interactions EXP 10 95,361,338 95,381,455 RGD:6480464 CTD
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 GBrowse link decreases activity EXP 10 95,361,338 95,381,455 RGD:6480464 CTD
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 GBrowse link increases expression EXP 10 95,361,338 95,381,455 RGD:6480464 CTD
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 GBrowse link multiple interactions ISO 10 95,361,338 95,381,455 RGD:6480464 CTD
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 GBrowse link decreases activity EXP 10 95,361,338 95,381,455 RGD:6480464 CTD
G Acvrl1 activin A receptor type II-like 1 GBrowse link decreases expression EXP 7 139,873,596 139,884,675 RGD:6480464 CTD
G Adrb1 adrenoceptor beta 1 GBrowse link increases expression EXP 1 263,025,655 263,027,055 RGD:6480464 CTD
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) GBrowse link decreases activity EXP 19 54,738,556 54,750,349 RGD:6480464 CTD
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) GBrowse link decreases expression ISO 19 54,738,556 54,750,349 RGD:6480464 CTD
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) GBrowse link decreases expression EXP 19 54,738,556 54,750,349 RGD:6480464 CTD
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) GBrowse link multiple interactions ISO 19 54,738,556 54,750,349 RGD:6480464 CTD
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) GBrowse link multiple interactions ISO 19 54,738,556 54,750,349 RGD:6480464 CTD
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) GBrowse link decreases expression ISO 19 54,738,556 54,750,349 RGD:6480464 CTD
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) GBrowse link multiple interactions EXP 19 54,738,556 54,750,349 RGD:6480464 CTD
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) GBrowse link decreases response to substance ISO 19 54,738,556 54,750,349 RGD:6480464 CTD
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) GBrowse link increases expression EXP 19 54,738,556 54,750,349 RGD:6480464 CTD
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) GBrowse link affects response to substance ISO 19 54,738,556 54,750,349 RGD:6480464 CTD
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) GBrowse link affects response to substance ISO 19 54,738,556 54,750,349 RGD:6480464 CTD
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) GBrowse link multiple interactions EXP 19 54,738,556 54,750,349 RGD:6480464 CTD
G Agtr1a angiotensin II receptor, type 1a GBrowse link affects expression EXP 17 40,629,318 40,684,982 RGD:6480464 CTD
G Agtr1a angiotensin II receptor, type 1a GBrowse link decreases expression EXP 17 40,629,318 40,684,982 RGD:6480464 CTD
G Agtr1a angiotensin II receptor, type 1a GBrowse link increases expression EXP 17 40,629,318 40,684,982 RGD:6480464 CTD
G Agtr1a angiotensin II receptor, type 1a GBrowse link multiple interactions EXP 17 40,629,318 40,684,982 RGD:6480464 CTD
G Agtr1a angiotensin II receptor, type 1a GBrowse link decreases expression EXP 17 40,629,318 40,684,982 RGD:6480464 CTD
G Agtr2 angiotensin II receptor, type 2 decreases expression EXP RGD:6480464 CTD
G Agtr2 angiotensin II receptor, type 2 increases expression EXP RGD:6480464 CTD
G Agtr2 angiotensin II receptor, type 2 decreases expression EXP RGD:6480464 CTD
G Agtr2 angiotensin II receptor, type 2 decreases expression EXP RGD:6480464 CTD
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link multiple interactions EXP 6 137,640,482 137,657,552 RGD:6480464 CTD
G Ang angiogenin, ribonuclease, RNase A family, 5 GBrowse link decreases expression ISO 15 27,083,089 27,083,526 RGD:6480464 CTD
G Angpt2 angiopoietin 2 GBrowse link multiple interactions EXP 16 75,891,757 75,942,255 RGD:6480464 CTD
G Apoe apolipoprotein E GBrowse link multiple interactions ISO 1 79,003,634 79,006,387 RGD:6480464 CTD
G Atf2 activating transcription factor 2 GBrowse link increases expression EXP 3 56,403,676 56,496,473 RGD:6480464 CTD
G Atp1a2 ATPase, Na+/K+ transporting, alpha 2 polypeptide GBrowse link increases expression EXP 13 88,258,993 88,283,918 RGD:6480464 CTD
G Atp1a3 ATPase, Na+/K+ transporting, alpha 3 polypeptide GBrowse link decreases expression EXP 1 80,280,714 80,309,834 RGD:6480464 CTD
G Avp arginine vasopressin GBrowse link multiple interactions EXP 3 118,205,007 118,206,985 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link decreases expression EXP 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link increases expression EXP 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bdkrb1 bradykinin receptor B1 GBrowse link increases expression EXP 6 129,760,129 129,762,545 RGD:6480464 CTD
G Bdkrb1 bradykinin receptor B1 GBrowse link multiple interactions EXP 6 129,760,129 129,762,545 RGD:6480464 CTD
G Bdkrb2 bradykinin receptor B2 GBrowse link increases expression EXP 6 129,744,781 129,748,851 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link decreases activity EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link decreases activity EXP 5 160,704,234 160,721,796 RGD:6480464 CTD
G Cat catalase GBrowse link increases activity EXP 3 88,654,077 88,686,212 RGD:6480464 CTD
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link decreases expression EXP 10 70,256,263 70,258,061 RGD:6480464 CTD
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link decreases expression EXP 10 70,256,263 70,258,061 RGD:6480464 CTD
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link decreases expression EXP 10 70,256,263 70,258,061 RGD:6480464 CTD
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link multiple interactions EXP 10 70,256,263 70,258,061 RGD:6480464 CTD
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link decreases expression ISO 10 70,256,263 70,258,061 RGD:6480464 CTD
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link multiple interactions ISO 10 70,256,263 70,258,061 RGD:6480464 CTD
G Cela2a chymotrypsin-like elastase family, member 2A GBrowse link decreases expression EXP 5 160,722,053 160,731,804 RGD:6480464 CTD
G Clu clusterin GBrowse link decreases expression EXP 15 45,365,779 45,405,314 RGD:6480464 CTD
G Cma1 chymase 1, mast cell GBrowse link decreases expression EXP 15 34,083,202 34,084,387 RGD:6480464 CTD
G Col1a1 collagen, type I, alpha 1 GBrowse link multiple interactions ISO 10 83,622,438 83,639,368 RGD:6480464 CTD
G Col4a1 collagen, type IV, alpha 1 GBrowse link multiple interactions EXP 16 83,045,183 83,157,835 RGD:6480464 CTD
G Col4a1 collagen, type IV, alpha 1 GBrowse link multiple interactions EXP 16 83,045,183 83,157,835 RGD:6480464 CTD
G Col4a1 collagen, type IV, alpha 1 GBrowse link decreases expression EXP 16 83,045,183 83,157,835 RGD:6480464 CTD
G Ctgf connective tissue growth factor GBrowse link decreases expression EXP 1 21,327,099 21,330,215 RGD:6480464 CTD
G Ctgf connective tissue growth factor GBrowse link decreases expression EXP 1 21,327,099 21,330,215 RGD:6480464 CTD
G Ctgf connective tissue growth factor GBrowse link decreases expression EXP 1 21,327,099 21,330,215 RGD:6480464 CTD
G Cyba cytochrome b-245, alpha polypeptide GBrowse link decreases expression ISO 19 52,713,150 52,721,609 RGD:6480464 CTD
G Cyba cytochrome b-245, alpha polypeptide GBrowse link multiple interactions ISO 19 52,713,150 52,721,609 RGD:6480464 CTD
G Cycs cytochrome c, somatic GBrowse link affects localization EXP 4 78,825,878 78,827,978 RGD:6480464 CTD
G Edn1 endothelin 1 GBrowse link multiple interactions EXP 17 28,303,886 28,309,775 RGD:6480464 CTD
G Epo erythropoietin GBrowse link decreases expression ISO 12 19,551,768 19,555,208 RGD:6480464 CTD
G Epo erythropoietin GBrowse link decreases expression ISO 12 19,551,768 19,555,208 RGD:6480464 CTD
G Epo erythropoietin GBrowse link multiple interactions EXP 12 19,551,768 19,555,208 RGD:6480464 CTD
G Epor erythropoietin receptor GBrowse link multiple interactions EXP 8 21,061,310 21,065,886 RGD:6480464 CTD
G F3 coagulation factor III (thromboplastin, tissue factor) GBrowse link decreases expression ISO 2 218,371,050 218,382,645 RGD:6480464 CTD
G F3 coagulation factor III (thromboplastin, tissue factor) GBrowse link multiple interactions ISO 2 218,371,050 218,382,645 RGD:6480464 CTD
G Faslg Fas ligand (TNF superfamily, member 6) GBrowse link decreases expression EXP 13 77,472,950 77,480,210 RGD:6480464 CTD
G Gh1 growth hormone 1 GBrowse link increases response to substance ISO 10 95,692,240 95,694,117 RGD:6480464 CTD
G Gja5 gap junction protein, alpha 5 GBrowse link multiple interactions ISO 2 191,824,118 191,843,867 RGD:6480464 CTD
G Gjc1 gap junction protein, gamma 1 multiple interactions ISO RGD:6480464 CTD
G Gjc1 gap junction protein, gamma 1 multiple interactions ISO RGD:6480464 CTD
G Gsk3b glycogen synthase kinase 3 beta GBrowse link multiple interactions EXP 11 64,284,731 64,428,698 RGD:6480464 CTD
G Has2 hyaluronan synthase 2 GBrowse link increases expression EXP 7 93,230,135 93,256,139 RGD:6480464 CTD
G Hmox1 heme oxygenase (decycling) 1 GBrowse link increases expression EXP 19 13,963,139 13,969,960 RGD:6480464 CTD
G Hyal1 hyaluronoglucosaminidase 1 GBrowse link decreases expression EXP 8 112,824,562 112,826,875 RGD:6480464 CTD
G Icam1 intercellular adhesion molecule 1 GBrowse link decreases expression EXP 8 20,040,177 20,051,939 RGD:6480464 CTD
G Icam1 intercellular adhesion molecule 1 GBrowse link decreases expression ISO 8 20,040,177 20,051,939 RGD:6480464 CTD
G Igf1 insulin-like growth factor 1 GBrowse link affects expression EXP 7 24,531,669 24,605,742 RGD:6480464 CTD
G Igf1 insulin-like growth factor 1 GBrowse link decreases expression EXP 7 24,531,669 24,605,742 RGD:6480464 CTD
G Igfbp1 insulin-like growth factor binding protein 1 GBrowse link increases expression EXP 14 87,950,222 87,955,289 RGD:6480464 CTD
G Il1a interleukin 1 alpha GBrowse link multiple interactions ISO 3 116,913,612 116,924,114 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link multiple interactions EXP 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link multiple interactions EXP 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link multiple interactions EXP 4 456,799 461,376 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link affects response to substance ISO 4 456,799 461,376 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link multiple interactions EXP 4 456,799 461,376 RGD:6480464 CTD
G Irak1 interleukin-1 receptor-associated kinase 1 GBrowse link multiple interactions ISO X 159,960,184 159,969,180 RGD:6480464 CTD
G Kdr kinase insert domain receptor multiple interactions EXP RGD:6480464 CTD
G Kng1 kininogen 1 GBrowse link increases response to substance EXP 11 80,109,499 80,131,887 RGD:6480464 CTD
G Lamb1 laminin, beta 1 GBrowse link multiple interactions EXP 6 49,115,671 49,183,374 RGD:6480464 CTD
G Lamb2 laminin, beta 2 multiple interactions EXP RGD:6480464 CTD
G Lep leptin GBrowse link increases response to substance ISO 4 55,943,837 55,945,938 RGD:6480464 CTD
G Mapk9 mitogen-activated protein kinase 9 GBrowse link increases expression EXP 10 35,353,486 35,384,319 RGD:6480464 CTD
G Mapk9 mitogen-activated protein kinase 9 GBrowse link increases phosphorylation EXP 10 35,353,486 35,384,319 RGD:6480464 CTD
G Myh6 myosin, heavy chain 6, cardiac muscle, alpha GBrowse link multiple interactions EXP 15 33,044,506 33,068,098 RGD:6480464 CTD
G Myh7 myosin, heavy chain 7, cardiac muscle, beta GBrowse link decreases expression EXP 15 33,072,928 33,094,595 RGD:6480464 CTD
G Myh7 myosin, heavy chain 7, cardiac muscle, beta GBrowse link multiple interactions EXP 15 33,072,928 33,094,595 RGD:6480464 CTD
G Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 GBrowse link multiple interactions EXP 18 56,638,891 56,677,831 RGD:6480464 CTD
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 GBrowse link decreases expression EXP 3 58,366,693 58,394,116 RGD:6480464 CTD
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 GBrowse link decreases activity EXP 2 233,091,013 233,187,501 RGD:6480464 CTD
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 GBrowse link multiple interactions EXP 2 233,091,013 233,187,501 RGD:6480464 CTD
G Noa1 nitric oxide associated 1 GBrowse link increases expression EXP 14 33,107,963 33,123,993 RGD:6480464 CTD
G Noa1 nitric oxide associated 1 GBrowse link increases activity EXP 14 33,107,963 33,123,993 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link decreases expression EXP 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link multiple interactions ISO 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link decreases expression ISO 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nos3 nitric oxide synthase 3, endothelial cell GBrowse link multiple interactions EXP 4 6,158,847 6,179,441 RGD:6480464 CTD
G Nos3 nitric oxide synthase 3, endothelial cell GBrowse link affects expression EXP 4 6,158,847 6,179,441 RGD:6480464 CTD
G Nos3 nitric oxide synthase 3, endothelial cell GBrowse link multiple interactions EXP 4 6,158,847 6,179,441 RGD:6480464 CTD
G Nos3 nitric oxide synthase 3, endothelial cell GBrowse link affects expression EXP 4 6,158,847 6,179,441 RGD:6480464 CTD
G Nos3 nitric oxide synthase 3, endothelial cell GBrowse link increases expression ISO 4 6,158,847 6,179,441 RGD:6480464 CTD
G Nos3 nitric oxide synthase 3, endothelial cell GBrowse link multiple interactions ISO 4 6,158,847 6,179,441 RGD:6480464 CTD
G Nppa natriuretic peptide A GBrowse link decreases expression ISO 5 165,074,518 165,075,827 RGD:6480464 CTD
G Nppa natriuretic peptide A GBrowse link decreases expression EXP 5 165,074,518 165,075,827 RGD:6480464 CTD
G Nppa natriuretic peptide A GBrowse link decreases expression EXP 5 165,074,518 165,075,827 RGD:6480464 CTD
G Nppa natriuretic peptide A GBrowse link decreases expression EXP 5 165,074,518 165,075,827 RGD:6480464 CTD
G Nppb natriuretic peptide B GBrowse link multiple interactions EXP 5 165,062,348 165,063,650 RGD:6480464 CTD
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 GBrowse link increases expression EXP 19 32,527,752 32,875,369 RGD:6480464 CTD
G Nrf1 nuclear respiratory factor 1 GBrowse link increases expression EXP 4 56,949,553 57,048,149 RGD:6480464 CTD
G Pdpn podoplanin GBrowse link increases expression EXP 5 162,142,251 162,175,921 RGD:6480464 CTD
G Potef POTE ankyrin domain family, member F GBrowse link decreases expression EXP 18 24,420,779 24,422,284 RGD:6480464 CTD
G Ppara peroxisome proliferator activated receptor alpha GBrowse link multiple interactions ISO 7 123,729,774 123,807,090 RGD:6480464 CTD
G Pparg peroxisome proliferator-activated receptor gamma GBrowse link decreases expression EXP 4 151,492,220 151,617,331 RGD:6480464 CTD
G Ppargc1a peroxisome proliferator-activated receptor gamma, coactivator 1 alpha GBrowse link increases expression EXP 14 64,278,115 64,370,912 RGD:6480464 CTD
G Prkca protein kinase C, alpha GBrowse link decreases expression EXP 10 97,367,196 97,638,910 RGD:6480464 CTD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link decreases expression EXP 13 64,427,288 64,432,978 RGD:6480464 CTD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link decreases expression ISO 13 64,427,288 64,432,978 RGD:6480464 CTD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link multiple interactions ISO 13 64,427,288 64,432,978 RGD:6480464 CTD
G Pth1r parathyroid hormone 1 receptor GBrowse link multiple interactions EXP 8 115,099,763 115,119,362 RGD:6480464 CTD
G Pthlh parathyroid hormone-like hormone GBrowse link multiple interactions EXP 4 184,887,702 184,898,841 RGD:6480464 CTD
G Ren renin GBrowse link multiple interactions ISO 13 46,262,936 46,275,213 RGD:6480464 CTD
G Ren renin GBrowse link increases expression ISO 13 46,262,936 46,275,213 RGD:6480464 CTD
G Ren renin GBrowse link increases expression EXP 13 46,262,936 46,275,213 RGD:6480464 CTD
G Ren renin GBrowse link increases activity EXP 13 46,262,936 46,275,213 RGD:6480464 CTD
G Ren renin GBrowse link multiple interactions ISO 13 46,262,936 46,275,213 RGD:6480464 CTD
G Ren renin GBrowse link decreases activity ISO 13 46,262,936 46,275,213 RGD:6480464 CTD
G Ren renin GBrowse link increases expression ISO 13 46,262,936 46,275,213 RGD:6480464 CTD
G Ren renin GBrowse link increases secretion ISO 13 46,262,936 46,275,213 RGD:6480464 CTD
G Ren renin GBrowse link increases expression ISO 13 46,262,936 46,275,213 RGD:6480464 CTD
G Ren renin GBrowse link multiple interactions ISO 13 46,262,936 46,275,213 RGD:6480464 CTD
G Ren renin GBrowse link multiple interactions ISO 13 46,262,936 46,275,213 RGD:6480464 CTD
G Ren renin GBrowse link increases expression EXP 13 46,262,936 46,275,213 RGD:6480464 CTD
G Ren renin GBrowse link increases expression ISO 13 46,262,936 46,275,213 RGD:6480464 CTD
G Ren renin GBrowse link multiple interactions ISO 13 46,262,936 46,275,213 RGD:6480464 CTD
G Ren renin GBrowse link increases expression EXP 13 46,262,936 46,275,213 RGD:6480464 CTD
G Ren renin GBrowse link increases expression EXP 13 46,262,936 46,275,213 RGD:6480464 CTD
G Ren renin GBrowse link increases expression ISO 13 46,262,936 46,275,213 RGD:6480464 CTD
G Ren renin GBrowse link increases secretion ISO 13 46,262,936 46,275,213 RGD:6480464 CTD
G Ren renin GBrowse link increases expression EXP 13 46,262,936 46,275,213 RGD:6480464 CTD
G Ren renin GBrowse link increases expression EXP 13 46,262,936 46,275,213 RGD:6480464 CTD
G Ren renin GBrowse link increases expression ISO 13 46,262,936 46,275,213 RGD:6480464 CTD
G Ren renin GBrowse link increases expression ISO 13 46,262,936 46,275,213 RGD:6480464 CTD
G Ren renin GBrowse link increases expression EXP 13 46,262,936 46,275,213 RGD:6480464 CTD
G Ren renin GBrowse link increases expression EXP 13 46,262,936 46,275,213 RGD:6480464 CTD
G Selp selectin P GBrowse link multiple interactions EXP 13 79,886,614 79,922,180 RGD:6480464 CTD
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link multiple interactions EXP 12 20,931,996 20,942,374 RGD:6480464 CTD
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link decreases expression EXP 12 20,931,996 20,942,374 RGD:6480464 CTD
G Slc15a2 solute carrier family 15 (H+/peptide transporter), member 2 GBrowse link multiple interactions ISO 11 65,819,551 65,849,924 RGD:6480464 CTD
G Slc22a12 solute carrier family 22 (organic anion/urate transporter), member 12 GBrowse link multiple interactions ISO 1 209,320,804 209,327,918 RGD:6480464 CTD
G Slc22a7 solute carrier family 22 (organic anion transporter), member 7 GBrowse link multiple interactions ISO 9 9,934,309 9,940,107 RGD:6480464 CTD
G Slc22a8 solute carrier family 22 (organic anion transporter), member 8 GBrowse link multiple interactions ISO 1 211,269,366 211,287,596 RGD:6480464 CTD
G Smad2 SMAD family member 2 GBrowse link multiple interactions EXP 18 73,180,520 73,241,707 RGD:6480464 CTD
G Smad7 SMAD family member 7 GBrowse link increases expression EXP 18 72,294,803 72,323,354 RGD:6480464 CTD
G Smad7 SMAD family member 7 GBrowse link increases expression EXP 18 72,294,803 72,323,354 RGD:6480464 CTD
G Smad7 SMAD family member 7 GBrowse link increases expression EXP 18 72,294,803 72,323,354 RGD:6480464 CTD
G Sod1 superoxide dismutase 1, soluble GBrowse link increases expression ISO 11 29,810,766 29,816,342 RGD:6480464 CTD
G Sod1 superoxide dismutase 1, soluble GBrowse link multiple interactions ISO 11 29,810,766 29,816,342 RGD:6480464 CTD
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link decreases activity EXP 1 41,862,997 41,870,327 RGD:6480464 CTD
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link multiple interactions ISO 1 41,862,997 41,870,327 RGD:6480464 CTD
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link decreases expression ISO 1 41,862,997 41,870,327 RGD:6480464 CTD
G Ssbp1 single-stranded DNA binding protein 1, mitochondrial GBrowse link increases expression EXP 4 68,027,304 68,036,581 RGD:6480464 CTD
G Stat3 signal transducer and activator of transcription 3 (acute-phase response factor) GBrowse link multiple interactions EXP 10 89,821,078 89,872,970 RGD:6480464 CTD
G Tek TEK tyrosine kinase, endothelial GBrowse link multiple interactions EXP 5 115,047,195 115,196,172 RGD:6480464 CTD
G Tgfb1 transforming growth factor, beta 1 GBrowse link multiple interactions EXP 1 80,894,705 80,911,020 RGD:6480464 CTD
G Tgfb1 transforming growth factor, beta 1 GBrowse link decreases expression EXP 1 80,894,705 80,911,020 RGD:6480464 CTD
G Tgfb1 transforming growth factor, beta 1 GBrowse link decreases expression EXP 1 80,894,705 80,911,020 RGD:6480464 CTD
G Tgfb1 transforming growth factor, beta 1 GBrowse link multiple interactions EXP 1 80,894,705 80,911,020 RGD:6480464 CTD
G Tgfb1 transforming growth factor, beta 1 GBrowse link multiple interactions EXP 1 80,894,705 80,911,020 RGD:6480464 CTD
G Tgfb1 transforming growth factor, beta 1 GBrowse link decreases expression EXP 1 80,894,705 80,911,020 RGD:6480464 CTD
G Tgfb1 transforming growth factor, beta 1 GBrowse link decreases expression EXP 1 80,894,705 80,911,020 RGD:6480464 CTD
G Tgfb1 transforming growth factor, beta 1 GBrowse link decreases expression EXP 1 80,894,705 80,911,020 RGD:6480464 CTD
G Tgfb1 transforming growth factor, beta 1 GBrowse link decreases expression EXP 1 80,894,705 80,911,020 RGD:6480464 CTD
G Tgfb1 transforming growth factor, beta 1 GBrowse link decreases expression EXP 1 80,894,705 80,911,020 RGD:6480464 CTD
G Tgfb1 transforming growth factor, beta 1 GBrowse link decreases expression EXP 1 80,894,705 80,911,020 RGD:6480464 CTD
G Tgfb1 transforming growth factor, beta 1 GBrowse link decreases expression EXP 1 80,894,705 80,911,020 RGD:6480464 CTD
G Tgfb1 transforming growth factor, beta 1 GBrowse link decreases expression EXP 1 80,894,705 80,911,020 RGD:6480464 CTD
G Tgfb2 transforming growth factor, beta 2 GBrowse link decreases expression EXP 13 102,718,703 102,818,768 RGD:6480464 CTD
G Tgfbi transforming growth factor, beta induced GBrowse link decreases secretion EXP 17 13,904,882 13,935,110 RGD:6480464 CTD
G Tgfbi transforming growth factor, beta induced GBrowse link multiple interactions EXP 17 13,904,882 13,935,110 RGD:6480464 CTD
G Tlr4 toll-like receptor 4 GBrowse link multiple interactions ISO 5 83,564,100 83,577,735 RGD:6480464 CTD
G Tmem27 transmembrane protein 27 GBrowse link decreases expression EXP X 51,118,665 51,149,768 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link decreases expression EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link decreases expression ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tomm20 translocase of outer mitochondrial membrane 20 homolog (yeast) GBrowse link decreases expression EXP 19 56,850,851 56,863,167 RGD:6480464 CTD
G Traf6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase GBrowse link multiple interactions ISO 3 86,827,582 86,847,408 RGD:6480464 CTD
G Vcam1 vascular cell adhesion molecule 1 GBrowse link affects expression ISO 2 212,277,654 212,297,376 RGD:6480464 CTD
G Vcam1 vascular cell adhesion molecule 1 GBrowse link decreases expression ISO 2 212,277,654 212,297,376 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link multiple interactions EXP 9 10,520,730 10,536,071 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link increases expression EXP 9 10,520,730 10,536,071 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link multiple interactions ISO 9 10,520,730 10,536,071 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link multiple interactions ISO 9 10,520,730 10,536,071 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link multiple interactions ISO 9 10,520,730 10,536,071 RGD:6480464 CTD
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 492574
    role 482262
      chemical role 208077
        inhibitor 73170
          enzyme inhibitor 68950
            angiotensin-converting enzyme inhibitor 684
              enalapril 214
                enalapril maleate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 492574
    subatomic particle 491537
      composite particle 491537
        hadron 491537
          baryon 491537
            nucleon 491537
              atomic nucleus 491537
                atom 491537
                  main group element atom 461203
                    p-block element atom 458699
                      carbon group element atom 410677
                        carbon atom 407233
                          organic molecular entity 407226
                            organic group 167766
                              organic divalent group 166601
                                organodiyl group 166601
                                  carbonyl group 166291
                                    carbonyl compound 166291
                                      carboxylic acid 121484
                                        carboacyl group 40976
                                          univalent carboacyl group 40976
                                            carbamoyl group 37195
                                              carboxamide 37186
                                                peptide 10075
                                                  oligopeptide 1235
                                                    dipeptide 297
                                                      enalaprilat (anhydrous) 232
                                                        enalapril 214
                                                          enalapril maleate 0
paths to the root

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