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Term:imipramine
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Accession:CHEBI:47499 term browser browse the term
Definition:A dibenzoazepine that has formula C19H24N2.
Synonyms:exact_synonym: 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine
 related_synonym: 10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine;   3-(5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE;   5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine;   Antideprin;   C19H24N2;   CN(C)CCCN1c2ccccc2CCc2ccccc12;   Imipramin;   InChI=1S/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H3;   InChIKey=BCGWQEUPMDMJNV-UHFFFAOYSA-N;   Irmin;   Melipramine;   N-(gamma-dimethylaminopropyl)iminodibenzyl;   imipraminum;   imizine
 alt_id: CHEBI:47498;   CHEBI:5881
 xref_casrn: 50-49-7
 xref: Beilstein:256892 "Beilstein Registry Number";   ChEMBL:100605 "ChEMBL COMPOUND";   ChemIDplus:50-49-7 "CAS Registry Number";   DrugBank:DB00458 "DrugBank";   Gmelin:1572523 "Gmelin Registry Number";   KEGG COMPOUND:50-49-7 "CAS Registry Number";   KEGG COMPOUND:C07049 "KEGG COMPOUND"
 xref_mesh: MESH:D007099
 xref: NIST Chemistry WebBook:50-49-7 "CAS Registry Number";   PDBeChem:IXX "PDBeChem";   Patent:US2554736 "Patent";   Wikipedia:Imipramine "Wikipedia"

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imipramine term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Aadat aminoadipate aminotransferase GBrowse link affects expression EXP 16 32,845,006 32,885,600 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link affects expression EXP 4 21,709,855 21,796,628 RGD:6480464 CTD
G Adrb1 adrenoceptor beta 1 GBrowse link multiple interactions EXP 1 263,025,655 263,027,055 RGD:6480464 CTD
G Adrb1 adrenoceptor beta 1 GBrowse link decreases activity EXP 1 263,025,655 263,027,055 RGD:6480464 CTD
G Adrb2 adrenoceptor beta 2, surface GBrowse link decreases expression ISO 18 58,174,958 58,177,000 RGD:6480464 CTD
G Alb albumin GBrowse link affects binding ISO 14 19,126,935 19,142,214 RGD:6480464 CTD
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 GBrowse link affects expression EXP 1 223,731,675 223,773,285 RGD:6480464 CTD
G Apoa4 apolipoprotein A-IV GBrowse link affects expression EXP 8 49,233,142 49,233,431 RGD:6480464 CTD
G Asah1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 GBrowse link increases expression ISO 16 54,279,253 54,311,084 RGD:6480464 CTD
G Asah1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 GBrowse link increases expression ISO 16 54,279,253 54,311,084 RGD:6480464 CTD
G Asns asparagine synthetase (glutamine-hydrolyzing) GBrowse link increases expression ISO 4 32,758,866 32,776,220 RGD:6480464 CTD
G Asns asparagine synthetase (glutamine-hydrolyzing) GBrowse link increases expression ISO 4 32,758,866 32,776,220 RGD:6480464 CTD
G Bdnf brain-derived neurotrophic factor increases expression ISO RGD:6480464 CTD
G Bdnf brain-derived neurotrophic factor affects expression EXP RGD:6480464 CTD
G Bdnf brain-derived neurotrophic factor increases expression EXP RGD:6480464 CTD
G Bdnf brain-derived neurotrophic factor multiple interactions EXP RGD:6480464 CTD
G Bdnf brain-derived neurotrophic factor increases expression EXP RGD:6480464 CTD
G Bhmt betaine-homocysteine S-methyltransferase GBrowse link affects expression EXP 2 23,923,651 23,943,320 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp7 caspase 7 GBrowse link increases activity ISO 1 262,689,300 262,721,591 RGD:6480464 CTD
G Casp7 caspase 7 GBrowse link multiple interactions ISO 1 262,689,300 262,721,591 RGD:6480464 CTD
G Cat catalase GBrowse link affects activity ISO 3 88,654,077 88,686,212 RGD:6480464 CTD
G Cdkn2c cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) GBrowse link affects expression EXP 5 131,012,524 131,017,679 RGD:6480464 CTD
G Ces2h carboxylesterase 2H GBrowse link affects expression EXP 19 34,910,981 34,925,547 RGD:6480464 CTD
G Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 GBrowse link affects expression EXP 8 119,149,810 119,165,515 RGD:6480464 CTD
G Cpped1 calcineurin-like phosphoesterase domain containing 1 GBrowse link affects expression EXP 10 3,577,406 3,698,276 RGD:6480464 CTD
G Creb1 cAMP responsive element binding protein 1 GBrowse link increases expression EXP 9 63,170,785 63,234,727 RGD:6480464 CTD
G Creb1 cAMP responsive element binding protein 1 GBrowse link multiple interactions EXP 9 63,170,785 63,234,727 RGD:6480464 CTD
G Creb1 cAMP responsive element binding protein 1 GBrowse link increases phosphorylation ISO 9 63,170,785 63,234,727 RGD:6480464 CTD
G Crem cAMP responsive element modulator GBrowse link affects expression EXP 17 62,770,633 62,837,670 RGD:6480464 CTD
G Crh corticotropin releasing hormone GBrowse link affects activity EXP 2 104,764,023 104,765,887 RGD:6480464 CTD
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 GBrowse link affects metabolic processing ISO 8 61,439,062 61,447,861 RGD:6480464 CTD
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 GBrowse link multiple interactions ISO 8 61,439,062 61,447,861 RGD:6480464 CTD
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 GBrowse link increases metabolic processing ISO 8 61,439,062 61,447,861 RGD:6480464 CTD
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 GBrowse link multiple interactions ISO 8 61,439,062 61,447,861 RGD:6480464 CTD
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 GBrowse link affects expression EXP 1 82,006,828 82,020,282 RGD:6480464 CTD
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 GBrowse link affects expression EXP 1 81,839,930 81,852,366 RGD:6480464 CTD
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 GBrowse link affects metabolic processing ISO 7 120,778,783 120,783,140 RGD:6480464 CTD
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 GBrowse link affects metabolic processing ISO 7 120,742,273 120,752,274 RGD:6480464 CTD
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 GBrowse link multiple interactions ISO 12 9,517,016 9,541,000 RGD:6480464 CTD
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 GBrowse link affects expression EXP 16 18,183,761 18,225,158 RGD:6480464 CTD
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 GBrowse link affects expression EXP 7 13,293,080 13,309,416 RGD:6480464 CTD
G Dcaf8 DDB1 and CUL4 associated factor 8 GBrowse link affects expression EXP 13 88,029,285 88,186,506 RGD:6480464 CTD
G Dnajc5 DnaJ (Hsp40) homolog, subfamily C, member 5 GBrowse link increases expression ISO 3 170,655,557 170,685,855 RGD:6480464 CTD
G Eif4b eukaryotic translation initiation factor 4B GBrowse link affects expression EXP 7 140,814,663 140,836,485 RGD:6480464 CTD
G Ephx1 epoxide hydrolase 1, microsomal (xenobiotic) GBrowse link affects expression EXP 13 96,722,973 96,752,940 RGD:6480464 CTD
G Erp29 endoplasmic reticulum protein 29 GBrowse link affects expression EXP 12 36,225,110 36,231,363 RGD:6480464 CTD
G Fabp1 fatty acid binding protein 1, liver GBrowse link increases expression ISO 4 104,412,200 104,415,981 RGD:6480464 CTD
G Fabp1 fatty acid binding protein 1, liver GBrowse link increases expression ISO 4 104,412,200 104,415,981 RGD:6480464 CTD
G Fos FBJ osteosarcoma oncogene GBrowse link decreases expression EXP 6 109,559,135 109,562,001 RGD:6480464 CTD
G Gap43 growth associated protein 43 GBrowse link decreases expression EXP 11 59,989,085 60,083,971 RGD:6480464 CTD
G Gckr glucokinase (hexokinase 4) regulator affects expression EXP RGD:6480464 CTD
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 GBrowse link increases expression ISO 1 185,941,893 185,984,348 RGD:6480464 CTD
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 GBrowse link increases expression ISO 1 185,941,893 185,984,348 RGD:6480464 CTD
G Gls2 glutaminase 2 (liver, mitochondrial) GBrowse link affects expression EXP 7 1,484,397 1,495,283 RGD:6480464 CTD
G Got2 glutamic-oxaloacetic transaminase 2, mitochondrial GBrowse link affects expression EXP 19 9,629,687 9,655,336 RGD:6480464 CTD
G Grb14 growth factor receptor bound protein 14 GBrowse link affects expression EXP 3 46,832,380 46,952,670 RGD:6480464 CTD
G Gstp1 glutathione S-transferase pi 1 GBrowse link decreases activity ISO 1 206,627,398 206,629,866 RGD:6480464 CTD
G H2afy H2A histone family, member Y GBrowse link affects expression EXP 17 14,457,307 14,520,963 RGD:6480464 CTD
G Hal histidine ammonia lyase GBrowse link affects expression EXP 7 30,520,913 30,551,145 RGD:6480464 CTD
G Hdac5 histone deacetylase 5 GBrowse link increases expression ISO 10 91,266,512 91,277,705 RGD:6480464 CTD
G Hmbs hydroxymethylbilane synthase GBrowse link decreases activity EXP 8 47,314,235 47,321,604 RGD:6480464 CTD
G Hmgb2 high mobility group box 2 GBrowse link affects expression EXP 16 36,131,304 36,133,878 RGD:6480464 CTD
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) GBrowse link increases expression ISO 2 51,737,090 51,754,583 RGD:6480464 CTD
G Hpn hepsin GBrowse link increases expression ISO 1 86,145,615 86,161,091 RGD:6480464 CTD
G Hpn hepsin GBrowse link increases expression ISO 1 86,145,615 86,161,091 RGD:6480464 CTD
G Hspa8 heat shock 70kDa protein 8 GBrowse link increases expression EXP 8 43,784,035 43,787,760 RGD:6480464 CTD
G Htr1a 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled GBrowse link affects expression EXP 2 36,434,518 36,435,786 RGD:6480464 CTD
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled GBrowse link decreases expression EXP 15 55,463,743 55,532,293 RGD:6480464 CTD
G Il33 interleukin 33 GBrowse link affects expression EXP 1 233,670,801 233,685,798 RGD:6480464 CTD
G Inhbe inhibin beta E GBrowse link increases expression ISO 7 67,308,713 67,310,138 RGD:6480464 CTD
G Inhbe inhibin beta E GBrowse link increases expression ISO 7 67,308,713 67,310,138 RGD:6480464 CTD
G Kcnh1 potassium voltage-gated channel, subfamily H (eag-related), member 1 GBrowse link multiple interactions ISO 13 108,129,617 108,407,815 RGD:6480464 CTD
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 GBrowse link multiple interactions ISO 4 6,192,644 6,224,285 RGD:6480464 CTD
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 GBrowse link multiple interactions ISO 4 6,192,644 6,224,285 RGD:6480464 CTD
G Kcnn2 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 GBrowse link decreases activity EXP 18 39,560,962 39,705,037 RGD:6480464 CTD
G LOC500300 similar to hypothetical protein MGC6835 GBrowse link increases expression ISO 4 153,000,782 153,002,562 RGD:6480464 CTD
G LOC500300 similar to hypothetical protein MGC6835 GBrowse link increases expression ISO 4 153,000,782 153,002,562 RGD:6480464 CTD
G Lox lysyl oxidase GBrowse link affects expression EXP 18 47,896,674 47,970,829 RGD:6480464 CTD
G Lss lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) GBrowse link increases expression ISO 20 12,507,575 12,534,612 RGD:6480464 CTD
G Lss lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) GBrowse link increases expression ISO 20 12,507,575 12,534,612 RGD:6480464 CTD
G Manba mannosidase, beta A, lysosomal GBrowse link affects expression EXP 2 232,983,989 233,077,788 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions EXP 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions EXP 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mlx MLX, MAX dimerization protein GBrowse link affects expression EXP 10 90,104,233 90,108,952 RGD:6480464 CTD
G Mrps18b mitochondrial ribosomal protein S18B GBrowse link affects expression EXP 20 2,985,972 2,992,031 RGD:6480464 CTD
G Msmo1 methylsterol monooxygenase 1 GBrowse link affects expression EXP 16 26,698,324 26,716,247 RGD:6480464 CTD
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 GBrowse link increases expression ISO 5 151,524,685 151,528,000 RGD:6480464 CTD
G Nrep neuronal regeneration related protein GBrowse link affects expression EXP 18 25,842,127 25,868,219 RGD:6480464 CTD
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 GBrowse link multiple interactions ISO 17 11,494,463 11,811,654 RGD:6480464 CTD
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 GBrowse link increases phosphorylation ISO 17 11,494,463 11,811,654 RGD:6480464 CTD
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 GBrowse link multiple interactions ISO 17 11,494,463 11,811,654 RGD:6480464 CTD
G Nupr1 nuclear protein, transcriptional regulator, 1 GBrowse link increases expression ISO 1 185,770,310 185,772,313 RGD:6480464 CTD
G Nupr1 nuclear protein, transcriptional regulator, 1 GBrowse link increases expression ISO 1 185,770,310 185,772,313 RGD:6480464 CTD
G Oaf OAF homolog (Drosophila) GBrowse link affects expression EXP 8 46,224,861 46,242,832 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link increases cleavage ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Pc pyruvate carboxylase GBrowse link affects expression EXP 1 207,112,853 207,212,737 RGD:6480464 CTD
G Pecr peroxisomal trans-2-enoyl-CoA reductase GBrowse link affects expression EXP 9 71,414,826 71,443,719 RGD:6480464 CTD
G Plcg1 phospholipase C, gamma 1 GBrowse link multiple interactions ISO 3 151,522,949 151,553,998 RGD:6480464 CTD
G Pomc proopiomelanocortin GBrowse link multiple interactions ISO 6 26,931,969 26,937,789 RGD:6480464 CTD
G Por P450 (cytochrome) oxidoreductase GBrowse link affects expression EXP 12 22,078,629 22,097,301 RGD:6480464 CTD
G Rbl2 retinoblastoma-like 2 GBrowse link affects expression EXP 19 17,045,131 17,092,597 RGD:6480464 CTD
G RT1-S3 RT1 class Ib, locus S3 GBrowse link affects expression EXP 20 2,815,943 2,820,644 RGD:6480464 CTD
G Scd stearoyl-CoA desaturase (delta-9-desaturase) GBrowse link increases expression ISO 1 249,358,105 249,371,164 RGD:6480464 CTD
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N GBrowse link increases expression ISO 6 128,461,775 128,469,309 RGD:6480464 CTD
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N GBrowse link increases expression ISO 6 128,461,775 128,469,309 RGD:6480464 CTD
G Serpini1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 GBrowse link increases expression EXP 2 166,445,765 166,555,032 RGD:6480464 CTD
G Sh3gl3 SH3-domain GRB2-like 3 GBrowse link affects expression EXP 1 138,398,336 138,529,056 RGD:6480464 CTD
G Slc22a3 solute carrier family 22 (extraneuronal monoamine transporter), member 3 GBrowse link multiple interactions ISO 1 42,690,158 42,781,895 RGD:6480464 CTD
G Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 GBrowse link decreases expression ISO 4 159,210,116 159,221,169 RGD:6480464 CTD
G Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 GBrowse link decreases expression ISO 4 159,210,116 159,221,169 RGD:6480464 CTD
G Slc47a1 solute carrier family 47, member 1 GBrowse link decreases activity ISO 10 47,514,258 47,548,353 RGD:6480464 CTD
G Slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 GBrowse link affects expression EXP 4 125,875,817 125,945,795 RGD:6480464 CTD
G Slco1a4 solute carrier organic anion transporter family, member 1a4 affects expression EXP RGD:6480464 CTD
G Srebf1 sterol regulatory element binding transcription factor 1 GBrowse link multiple interactions ISO 10 46,461,684 46,483,646 RGD:6480464 CTD
G Srebf2 sterol regulatory element binding transcription factor 2 GBrowse link multiple interactions ISO 7 120,522,511 120,580,212 RGD:6480464 CTD
G St13 suppression of tumorigenicity 13 GBrowse link affects expression EXP 7 119,694,123 119,728,936 RGD:6480464 CTD
G Stbd1 starch binding domain 1 GBrowse link affects expression EXP 14 17,031,752 17,035,157 RGD:6480464 CTD
G Stmn1 stathmin 1 GBrowse link affects expression EXP 5 153,226,420 153,232,084 RGD:6480464 CTD
G Sult2a6 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6 GBrowse link affects expression EXP 1 74,553,799 74,605,247 RGD:6480464 CTD
G Tac1 tachykinin, precursor 1 GBrowse link decreases expression EXP 4 32,649,666 32,657,632 RGD:6480464 CTD
G Tagln transgelin GBrowse link decreases expression ISO 8 48,902,208 48,907,682 RGD:6480464 CTD
G Tagln transgelin GBrowse link decreases expression ISO 8 48,902,208 48,907,682 RGD:6480464 CTD
G Tex261 testis expressed 261 GBrowse link affects expression EXP 4 117,963,579 117,968,532 RGD:6480464 CTD
G Timm10b translocase of inner mitochondrial membrane 10 homolog B GBrowse link affects expression EXP 1 163,369,731 163,372,577 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 GBrowse link affects expression EXP 16 19,425,401 19,427,557 RGD:6480464 CTD
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 GBrowse link affects expression EXP 9 87,091,241 87,098,362 RGD:6480464 CTD
G Ugt2a1 UDP glucuronosyltransferase 2 family, polypeptide A1 GBrowse link affects expression EXP 14 22,047,612 22,071,582 RGD:6480464 CTD
G Ugt2b17 UDP glucuronosyltransferase 2 family, polypeptide B17 GBrowse link affects expression EXP 14 22,639,182 22,650,931 RGD:6480464 CTD
G Wipi1 WD repeat domain, phosphoinositide interacting 1 GBrowse link increases expression ISO 10 98,722,266 98,753,713 RGD:6480464 CTD
G Wipi1 WD repeat domain, phosphoinositide interacting 1 GBrowse link increases expression ISO 10 98,722,266 98,753,713 RGD:6480464 CTD
clomipramine term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Aadat aminoadipate aminotransferase GBrowse link affects expression EXP 16 32,845,006 32,885,600 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link affects expression EXP 4 21,709,855 21,796,628 RGD:6480464 CTD
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 GBrowse link affects expression EXP 1 223,731,675 223,773,285 RGD:6480464 CTD
G Ap1s1 adaptor-related protein complex 1, sigma 1 subunit GBrowse link decreases expression ISO 12 20,907,855 20,918,301 RGD:6480464 CTD
G Ap1s1 adaptor-related protein complex 1, sigma 1 subunit GBrowse link decreases expression ISO 12 20,907,855 20,918,301 RGD:6480464 CTD
G Apoa4 apolipoprotein A-IV GBrowse link affects expression EXP 8 49,233,142 49,233,431 RGD:6480464 CTD
G Asns asparagine synthetase (glutamine-hydrolyzing) GBrowse link increases expression ISO 4 32,758,866 32,776,220 RGD:6480464 CTD
G Bhmt betaine-homocysteine S-methyltransferase GBrowse link affects expression EXP 2 23,923,651 23,943,320 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp7 caspase 7 GBrowse link multiple interactions ISO 1 262,689,300 262,721,591 RGD:6480464 CTD
G Casp7 caspase 7 GBrowse link increases activity ISO 1 262,689,300 262,721,591 RGD:6480464 CTD
G Cat catalase GBrowse link decreases expression ISO 3 88,654,077 88,686,212 RGD:6480464 CTD
G Cdkn2c cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) GBrowse link affects expression EXP 5 131,012,524 131,017,679 RGD:6480464 CTD
G Ces2h carboxylesterase 2H GBrowse link affects expression EXP 19 34,910,981 34,925,547 RGD:6480464 CTD
G Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 GBrowse link affects expression EXP 8 119,149,810 119,165,515 RGD:6480464 CTD
G Cpped1 calcineurin-like phosphoesterase domain containing 1 GBrowse link affects expression EXP 10 3,577,406 3,698,276 RGD:6480464 CTD
G Crem cAMP responsive element modulator GBrowse link affects expression EXP 17 62,770,633 62,837,670 RGD:6480464 CTD
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 GBrowse link affects expression EXP 1 82,006,828 82,020,282 RGD:6480464 CTD
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 GBrowse link affects expression EXP 1 81,839,930 81,852,366 RGD:6480464 CTD
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 GBrowse link affects expression EXP 16 18,183,761 18,225,158 RGD:6480464 CTD
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 GBrowse link affects expression EXP 7 13,293,080 13,309,416 RGD:6480464 CTD
G Dcaf8 DDB1 and CUL4 associated factor 8 GBrowse link affects expression EXP 13 88,029,285 88,186,506 RGD:6480464 CTD
G Drd2 dopamine receptor D2 GBrowse link increases expression EXP 8 52,641,160 52,707,749 RGD:6480464 CTD
G Eif4b eukaryotic translation initiation factor 4B GBrowse link affects expression EXP 7 140,814,663 140,836,485 RGD:6480464 CTD
G Ephx1 epoxide hydrolase 1, microsomal (xenobiotic) GBrowse link affects expression EXP 13 96,722,973 96,752,940 RGD:6480464 CTD
G Erp29 endoplasmic reticulum protein 29 GBrowse link affects expression EXP 12 36,225,110 36,231,363 RGD:6480464 CTD
G Fabp1 fatty acid binding protein 1, liver GBrowse link increases expression ISO 4 104,412,200 104,415,981 RGD:6480464 CTD
G Gckr glucokinase (hexokinase 4) regulator affects expression EXP RGD:6480464 CTD
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 GBrowse link increases expression ISO 1 185,941,893 185,984,348 RGD:6480464 CTD
G Gls2 glutaminase 2 (liver, mitochondrial) GBrowse link affects expression EXP 7 1,484,397 1,495,283 RGD:6480464 CTD
G Got2 glutamic-oxaloacetic transaminase 2, mitochondrial GBrowse link affects expression EXP 19 9,629,687 9,655,336 RGD:6480464 CTD
G Grb14 growth factor receptor bound protein 14 GBrowse link affects expression EXP 3 46,832,380 46,952,670 RGD:6480464 CTD
G Gstp1 glutathione S-transferase pi 1 GBrowse link decreases activity ISO 1 206,627,398 206,629,866 RGD:6480464 CTD
G H2afy H2A histone family, member Y GBrowse link affects expression EXP 17 14,457,307 14,520,963 RGD:6480464 CTD
G Hal histidine ammonia lyase GBrowse link affects expression EXP 7 30,520,913 30,551,145 RGD:6480464 CTD
G Hmgb2 high mobility group box 2 GBrowse link affects expression EXP 16 36,131,304 36,133,878 RGD:6480464 CTD
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) GBrowse link increases expression ISO 2 51,737,090 51,754,583 RGD:6480464 CTD
G Hpn hepsin GBrowse link increases expression ISO 1 86,145,615 86,161,091 RGD:6480464 CTD
G Htr2c 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled GBrowse link affects binding ISO X 31,012,921 31,244,127 RGD:6480464 CTD
G Htr2c 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled GBrowse link increases expression EXP X 31,012,921 31,244,127 RGD:6480464 CTD
G Il1a interleukin 1 alpha GBrowse link multiple interactions ISO 3 116,913,612 116,924,114 RGD:6480464 CTD
G Il33 interleukin 33 GBrowse link affects expression EXP 1 233,670,801 233,685,798 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link multiple interactions ISO 4 456,799 461,376 RGD:6480464 CTD
G Inhbe inhibin beta E GBrowse link increases expression ISO 7 67,308,713 67,310,138 RGD:6480464 CTD
G Inhbe inhibin beta E GBrowse link increases expression ISO 7 67,308,713 67,310,138 RGD:6480464 CTD
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 GBrowse link multiple interactions ISO 4 6,192,644 6,224,285 RGD:6480464 CTD
G LOC500300 similar to hypothetical protein MGC6835 GBrowse link increases expression ISO 4 153,000,782 153,002,562 RGD:6480464 CTD
G LOC500300 similar to hypothetical protein MGC6835 GBrowse link increases expression ISO 4 153,000,782 153,002,562 RGD:6480464 CTD
G Lox lysyl oxidase GBrowse link affects expression EXP 18 47,896,674 47,970,829 RGD:6480464 CTD
G Lss lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) GBrowse link increases expression ISO 20 12,507,575 12,534,612 RGD:6480464 CTD
G Manba mannosidase, beta A, lysosomal GBrowse link affects expression EXP 2 232,983,989 233,077,788 RGD:6480464 CTD
G Mlx MLX, MAX dimerization protein GBrowse link affects expression EXP 10 90,104,233 90,108,952 RGD:6480464 CTD
G Mrps18b mitochondrial ribosomal protein S18B GBrowse link affects expression EXP 20 2,985,972 2,992,031 RGD:6480464 CTD
G Msmo1 methylsterol monooxygenase 1 GBrowse link affects expression EXP 16 26,698,324 26,716,247 RGD:6480464 CTD
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 GBrowse link increases expression ISO 5 151,524,685 151,528,000 RGD:6480464 CTD
G Nrep neuronal regeneration related protein GBrowse link affects expression EXP 18 25,842,127 25,868,219 RGD:6480464 CTD
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 GBrowse link increases phosphorylation ISO 17 11,494,463 11,811,654 RGD:6480464 CTD
G Nupr1 nuclear protein, transcriptional regulator, 1 GBrowse link increases expression ISO 1 185,770,310 185,772,313 RGD:6480464 CTD
G Nupr1 nuclear protein, transcriptional regulator, 1 GBrowse link increases expression ISO 1 185,770,310 185,772,313 RGD:6480464 CTD
G Oaf OAF homolog (Drosophila) GBrowse link affects expression EXP 8 46,224,861 46,242,832 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link increases cleavage ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Pc pyruvate carboxylase GBrowse link affects expression EXP 1 207,112,853 207,212,737 RGD:6480464 CTD
G Pecr peroxisomal trans-2-enoyl-CoA reductase GBrowse link affects expression EXP 9 71,414,826 71,443,719 RGD:6480464 CTD
G Phyh phytanoyl-CoA 2-hydroxylase GBrowse link increases expression ISO 17 84,418,173 84,435,073 RGD:6480464 CTD
G Por P450 (cytochrome) oxidoreductase GBrowse link affects expression EXP 12 22,078,629 22,097,301 RGD:6480464 CTD
G Prl prolactin GBrowse link increases expression ISO 17 44,699,101 44,709,162 RGD:6480464 CTD
G Prl prolactin GBrowse link affects secretion ISO 17 44,699,101 44,709,162 RGD:6480464 CTD
G Prl prolactin GBrowse link increases secretion ISO 17 44,699,101 44,709,162 RGD:6480464 CTD
G Prl prolactin GBrowse link multiple interactions ISO 17 44,699,101 44,709,162 RGD:6480464 CTD
G Prl prolactin GBrowse link increases expression ISO 17 44,699,101 44,709,162 RGD:6480464 CTD
G Proc protein C GBrowse link increases expression ISO 18 24,563,368 24,573,715 RGD:6480464 CTD
G Rbl2 retinoblastoma-like 2 GBrowse link affects expression EXP 19 17,045,131 17,092,597 RGD:6480464 CTD
G RT1-S3 RT1 class Ib, locus S3 GBrowse link affects expression EXP 20 2,815,943 2,820,644 RGD:6480464 CTD
G Scd stearoyl-CoA desaturase (delta-9-desaturase) GBrowse link increases expression ISO 1 249,358,105 249,371,164 RGD:6480464 CTD
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N GBrowse link increases expression ISO 6 128,461,775 128,469,309 RGD:6480464 CTD
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N GBrowse link increases expression ISO 6 128,461,775 128,469,309 RGD:6480464 CTD
G Sh3gl3 SH3-domain GRB2-like 3 GBrowse link affects expression EXP 1 138,398,336 138,529,056 RGD:6480464 CTD
G Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 GBrowse link decreases expression ISO 4 159,210,116 159,221,169 RGD:6480464 CTD
G Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 GBrowse link decreases expression ISO 4 159,210,116 159,221,169 RGD:6480464 CTD
G Slc6a4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 GBrowse link multiple interactions ISO 10 67,134,790 67,155,891 RGD:6480464 CTD
G Slc6a4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 GBrowse link multiple interactions ISO 10 67,134,790 67,155,891 RGD:6480464 CTD
G Slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 GBrowse link affects expression EXP 4 125,875,817 125,945,795 RGD:6480464 CTD
G Slco1a4 solute carrier organic anion transporter family, member 1a4 affects expression EXP RGD:6480464 CTD
G Srebf1 sterol regulatory element binding transcription factor 1 GBrowse link multiple interactions ISO 10 46,461,684 46,483,646 RGD:6480464 CTD
G Srebf2 sterol regulatory element binding transcription factor 2 GBrowse link multiple interactions ISO 7 120,522,511 120,580,212 RGD:6480464 CTD
G St13 suppression of tumorigenicity 13 GBrowse link affects expression EXP 7 119,694,123 119,728,936 RGD:6480464 CTD
G Stbd1 starch binding domain 1 GBrowse link affects expression EXP 14 17,031,752 17,035,157 RGD:6480464 CTD
G Stmn1 stathmin 1 GBrowse link affects expression EXP 5 153,226,420 153,232,084 RGD:6480464 CTD
G Sult2a6 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6 GBrowse link affects expression EXP 1 74,553,799 74,605,247 RGD:6480464 CTD
G Tac1 tachykinin, precursor 1 GBrowse link decreases expression EXP 4 32,649,666 32,657,632 RGD:6480464 CTD
G Tagln transgelin GBrowse link decreases expression ISO 8 48,902,208 48,907,682 RGD:6480464 CTD
G Tex261 testis expressed 261 GBrowse link affects expression EXP 4 117,963,579 117,968,532 RGD:6480464 CTD
G Timm10b translocase of inner mitochondrial membrane 10 homolog B GBrowse link affects expression EXP 1 163,369,731 163,372,577 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 GBrowse link affects expression EXP 16 19,425,401 19,427,557 RGD:6480464 CTD
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 GBrowse link affects expression EXP 9 87,091,241 87,098,362 RGD:6480464 CTD
G Ugt2a1 UDP glucuronosyltransferase 2 family, polypeptide A1 GBrowse link affects expression EXP 14 22,047,612 22,071,582 RGD:6480464 CTD
G Ugt2b17 UDP glucuronosyltransferase 2 family, polypeptide B17 GBrowse link affects expression EXP 14 22,639,182 22,650,931 RGD:6480464 CTD
G Wipi1 WD repeat domain, phosphoinositide interacting 1 GBrowse link increases expression ISO 10 98,722,266 98,753,713 RGD:6480464 CTD
G Wipi1 WD repeat domain, phosphoinositide interacting 1 GBrowse link increases expression ISO 10 98,722,266 98,753,713 RGD:6480464 CTD
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 501881
    role 491510
      biological role 489686
        pharmacological role 129710
          neurotransmitter agent 38735
            adrenergic agent 16217
              adrenergic uptake inhibitor 4537
                imipramine 234
                  clomipramine 101
                  imipramine hydrochloride 0
                  trimipramine + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 501881
    subatomic particle 500845
      composite particle 500845
        hadron 500845
          baryon 500845
            nucleon 500845
              atomic nucleus 500845
                atom 500845
                  main group element atom 470301
                    p-block element atom 467779
                      carbon group element atom 419149
                        carbon atom 415667
                          organic molecular entity 415660
                            organic molecule 365810
                              organic cyclic compound 304492
                                organic heterocyclic compound 158510
                                  organic heteropolycyclic compound 97199
                                    organic heterotricyclic compound 38441
                                      dibenzoazepine 578
                                        imipramine 234
                                          clomipramine 101
                                          imipramine hydrochloride 0
                                          trimipramine + 0
paths to the root

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