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Term:docetaxel anhydrous
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Accession:CHEBI:4672 term browser browse the term
Definition:A tetracyclic diterpenoid that is paclitaxel with the N-benzyloxycarbonyl group replaced by N-tert-butoxycarbonyl, and the acetoxy group at position 10 replaced by a hydroxy group.
Synonyms:exact_synonym: 4-(acetyloxy)-13alpha-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7beta,10beta-trihydroxy-9-oxo-5beta,20-epoxytax-11-en-2alpha-yl benzoate
 related_synonym: C43H53NO14;   Docetaxel;   InChI=1S/C43H53NO14/c1-22-26(55-37(51)32(48)30(24-15-11-9-12-16-24)44-38(52)58-39(3,4)5)20-43(53)35(56-36(50)25-17-13-10-14-18-25)33-41(8,34(49)31(47)29(22)40(43,6)7)27(46)19-28-42(33,21-54-28)57-23(2)45/h9-18,26-28,30-33,35,46-48,53H,19-21H2,1-8H3,(H,44,52)/t26-,27-,28+,30-,31+,32+,33-,35-,41+,42-,43+/m0/s1;   InChIKey=ZDZOTLJHXYCWBA-VCVYQWHSSA-N;   N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel;   N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol;   TXL;   [H][C@@]1(C[C@@]2(O)[C@@H](OC(=O)c3ccccc3)[C@]3([H])[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C(=O)[C@H](O)C(=C1C)C2(C)C)OC(C)=O)OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)c1ccccc1
 xref_casrn: 114977-28-5
 xref: Beilstein:4290183 "Beilstein Registry Number";   ChEMBL:109097 "ChEMBL COMPOUND";   ChemIDplus:114977-28-5 "CAS Registry Number";   DrugBank:DB01248 "DrugBank";   KEGG COMPOUND:114977-28-5 "CAS Registry Number";   KEGG COMPOUND:C11231 "KEGG COMPOUND";   KEGG DRUG:D07866 "KEGG DRUG"
 xref_mesh: MESH:C067311
 xref: Patent:EP253738 "Patent";   Patent:US4814470 "Patent";   Wikipedia:Docetaxel "Wikipedia"

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Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Abca1 ATP-binding cassette, subfamily A (ABC1), member 1 GBrowse link multiple interactions ISO 5 70,493,357 70,583,729 RGD:6480464 CTD
G Abca12 ATP-binding cassette, subfamily A (ABC1), member 12 GBrowse link multiple interactions ISO 9 70,328,327 70,501,128 RGD:6480464 CTD
G Abca3 ATP-binding cassette, subfamily A (ABC1), member 3 GBrowse link multiple interactions ISO 10 13,619,865 13,665,066 RGD:6480464 CTD
G Abca4 ATP-binding cassette, subfamily A (ABC1), member 4 GBrowse link multiple interactions ISO 2 218,712,663 218,849,896 RGD:6480464 CTD
G Abca5 ATP-binding cassette, subfamily A (ABC1), member 5 GBrowse link multiple interactions ISO 10 99,724,778 99,793,593 RGD:6480464 CTD
G Abca6 ATP-binding cassette, subfamily A (ABC1), member 6 GBrowse link multiple interactions ISO 10 99,626,334 99,693,870 RGD:6480464 CTD
G Abca7 ATP-binding cassette, subfamily A (ABC1), member 7 GBrowse link multiple interactions ISO 7 11,203,983 11,222,960 RGD:6480464 CTD
G Abca8 ATP-binding cassette, subfamily A (ABC1), member 8 GBrowse link multiple interactions ISO 10 99,392,053 99,452,833 RGD:6480464 CTD
G Abca9 ATP-binding cassette, subfamily A (ABC1), member 9 GBrowse link multiple interactions ISO 10 99,558,803 99,619,870 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link multiple interactions ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link decreases response to substance ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link increases expression ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link increases expression ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link increases response to substance ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link increases expression ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link multiple interactions ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link multiple interactions ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link decreases expression ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link multiple interactions ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link decreases response to substance ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb4 ATP-binding cassette, subfamily B (MDR/TAP), member 4 GBrowse link multiple interactions ISO 4 21,946,274 22,004,328 RGD:6480464 CTD
G Abcb6 ATP-binding cassette, subfamily B (MDR/TAP), member 6 GBrowse link multiple interactions ISO 9 74,454,805 74,463,083 RGD:6480464 CTD
G Abcb8 ATP-binding cassette, subfamily B (MDR/TAP), member 8 GBrowse link multiple interactions ISO 4 6,133,928 6,148,509 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 GBrowse link increases expression ISO 10 452,239 575,705 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 GBrowse link multiple interactions ISO 10 452,239 575,705 RGD:6480464 CTD
G Abcc10 ATP-binding cassette, subfamily C (CFTR/MRP), member 10 GBrowse link multiple interactions ISO 9 10,219,822 10,239,734 RGD:6480464 CTD
G Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 affects transport ISO RGD:6480464 CTD
G Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 multiple interactions ISO RGD:6480464 CTD
G Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 multiple interactions ISO RGD:6480464 CTD
G Abcc3 ATP-binding cassette, subfamily C (CFTR/MRP), member 3 GBrowse link multiple interactions ISO 10 82,986,552 83,030,799 RGD:6480464 CTD
G Abcc4 ATP-binding cassette, subfamily C (CFTR/MRP), member 4 GBrowse link multiple interactions ISO 15 103,384,848 103,611,238 RGD:6480464 CTD
G Abcc5 ATP-binding cassette, subfamily C (CFTR/MRP), member 5 GBrowse link multiple interactions ISO 11 82,714,334 82,809,354 RGD:6480464 CTD
G Abcc6 ATP-binding cassette, subfamily C (CFTR/MRP), member 6 GBrowse link multiple interactions ISO 1 96,448,588 96,524,655 RGD:6480464 CTD
G Abcc9 ATP-binding cassette, subfamily C (CFTR/MRP), member 9 multiple interactions ISO RGD:6480464 CTD
G Abcd2 ATP-binding cassette, subfamily D (ALD), member 2 GBrowse link multiple interactions ISO 7 129,542,758 129,591,363 RGD:6480464 CTD
G Abce1 ATP-binding cassette, subfamily E (OABP), member 1 GBrowse link multiple interactions ISO 19 30,093,741 30,118,625 RGD:6480464 CTD
G Abcg2 ATP-binding cassette, subfamily G (WHITE), member 2 GBrowse link multiple interactions ISO 4 87,502,584 87,560,017 RGD:6480464 CTD
G Aco2 aconitase 2, mitochondrial GBrowse link multiple interactions ISO 7 120,223,788 120,266,944 RGD:6480464 CTD
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link multiple interactions ISO 6 137,640,482 137,657,552 RGD:6480464 CTD
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link decreases phosphorylation ISO 6 137,640,482 137,657,552 RGD:6480464 CTD
G Aldoa aldolase A, fructose-bisphosphate GBrowse link multiple interactions ISO 1 185,970,658 185,974,615 RGD:6480464 CTD
G Ar androgen receptor GBrowse link multiple interactions ISO X 85,949,507 86,119,199 RGD:6480464 CTD
G Ar androgen receptor GBrowse link decreases localization ISO X 85,949,507 86,119,199 RGD:6480464 CTD
G Bad BCL2-associated agonist of cell death GBrowse link decreases phosphorylation ISO 1 209,617,373 209,626,292 RGD:6480464 CTD
G Bad BCL2-associated agonist of cell death GBrowse link multiple interactions ISO 1 209,617,373 209,626,292 RGD:6480464 CTD
G Bak1 BCL2-antagonist/killer 1 GBrowse link multiple interactions ISO 20 5,255,954 5,264,593 RGD:6480464 CTD
G Bak1 BCL2-antagonist/killer 1 GBrowse link multiple interactions ISO 20 5,255,954 5,264,593 RGD:6480464 CTD
G Bak1 BCL2-antagonist/killer 1 GBrowse link increases activity ISO 20 5,255,954 5,264,593 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link multiple interactions ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link multiple interactions ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link affects localization ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link multiple interactions ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link increases activity ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link increases expression ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link increases expression ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link multiple interactions ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link multiple interactions ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link increases expression ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link increases expression ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link increases expression ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link increases expression ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link multiple interactions ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link multiple interactions ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link multiple interactions ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link increases expression ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link multiple interactions ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link multiple interactions ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link multiple interactions ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link increases phosphorylation ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link increases phosphorylation ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link affects response to substance ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link multiple interactions ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link multiple interactions ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link multiple interactions ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link increases phosphorylation ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2l1 Bcl2-like 1 GBrowse link decreases response to substance ISO 3 143,129,087 143,180,199 RGD:6480464 CTD
G Bcl2l1 Bcl2-like 1 GBrowse link multiple interactions ISO 3 143,129,087 143,180,199 RGD:6480464 CTD
G Bcl2l1 Bcl2-like 1 GBrowse link decreases expression ISO 3 143,129,087 143,180,199 RGD:6480464 CTD
G Bcl2l1 Bcl2-like 1 GBrowse link decreases expression ISO 3 143,129,087 143,180,199 RGD:6480464 CTD
G Bcl2l11 BCL2-like 11 (apoptosis facilitator) GBrowse link multiple interactions ISO 3 115,692,323 115,722,701 RGD:6480464 CTD
G Bcl2l11 BCL2-like 11 (apoptosis facilitator) GBrowse link increases degradation ISO 3 115,692,323 115,722,701 RGD:6480464 CTD
G Birc5 baculoviral IAP repeat-containing 5 decreases response to substance ISO RGD:6480464 CTD
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO RGD:6480464 CTD
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO RGD:6480464 CTD
G Birc5 baculoviral IAP repeat-containing 5 decreases response to substance ISO RGD:6480464 CTD
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B GBrowse link affects response to substance ISO 3 105,063,018 105,116,145 RGD:6480464 CTD
G Casp2 caspase 2 GBrowse link increases activity ISO 4 70,029,728 70,047,164 RGD:6480464 CTD
G Casp2 caspase 2 GBrowse link multiple interactions ISO 4 70,029,728 70,047,164 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases cleavage ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases cleavage ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp8 caspase 8 GBrowse link increases activity ISO 9 57,389,353 57,437,803 RGD:6480464 CTD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link multiple interactions ISO 5 160,704,234 160,721,796 RGD:6480464 CTD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link multiple interactions ISO 5 160,704,234 160,721,796 RGD:6480464 CTD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link multiple interactions ISO 5 160,704,234 160,721,796 RGD:6480464 CTD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link multiple interactions ISO 5 160,704,234 160,721,796 RGD:6480464 CTD
G Ccnb1 cyclin B1 GBrowse link multiple interactions ISO 2 31,574,600 31,581,784 RGD:6480464 CTD
G Cdk1 cyclin-dependent kinase 1 GBrowse link increases response to substance ISO 20 20,018,044 20,044,030 RGD:6480464 CTD
G Cdk1 cyclin-dependent kinase 1 GBrowse link increases activity ISO 20 20,018,044 20,044,030 RGD:6480464 CTD
G Cdk1 cyclin-dependent kinase 1 GBrowse link multiple interactions ISO 20 20,018,044 20,044,030 RGD:6480464 CTD
G Cdk1 cyclin-dependent kinase 1 GBrowse link multiple interactions ISO 20 20,018,044 20,044,030 RGD:6480464 CTD
G Cdk1 cyclin-dependent kinase 1 GBrowse link increases activity ISO 20 20,018,044 20,044,030 RGD:6480464 CTD
G Cdk2 cyclin dependent kinase 2 GBrowse link multiple interactions ISO 7 2,000,196 2,007,682 RGD:6480464 CTD
G Cdk2 cyclin dependent kinase 2 GBrowse link increases activity ISO 7 2,000,196 2,007,682 RGD:6480464 CTD
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link multiple interactions ISO 20 7,376,325 7,386,778 RGD:6480464 CTD
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link increases expression ISO 20 7,376,325 7,386,778 RGD:6480464 CTD
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link multiple interactions ISO 20 7,376,325 7,386,778 RGD:6480464 CTD
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link multiple interactions ISO 20 7,376,325 7,386,778 RGD:6480464 CTD
G Cdkn2a cyclin-dependent kinase inhibitor 2A GBrowse link decreases expression ISO 5 108,908,749 108,916,380 RGD:6480464 CTD
G Chfr checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase GBrowse link affects response to substance ISO 12 46,651,265 46,684,689 RGD:6480464 CTD
G Chfr checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase GBrowse link decreases response to substance ISO 12 46,651,265 46,684,689 RGD:6480464 CTD
G Ckm creatine kinase, muscle GBrowse link multiple interactions ISO 1 78,762,202 78,772,681 RGD:6480464 CTD
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) GBrowse link increases secretion ISO 10 39,665,850 39,667,831 RGD:6480464 CTD
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases expression ISO RGD:6480464 CTD
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 GBrowse link affects response to substance ISO 6 2,548,224 2,553,767 RGD:6480464 CTD
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 GBrowse link increases response to substance ISO 12 9,517,016 9,541,000 RGD:6480464 CTD
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 GBrowse link increases expression ISO 12 9,517,016 9,541,000 RGD:6480464 CTD
G Dbi diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) multiple interactions ISO RGD:6480464 CTD
G Dpyd dihydropyrimidine dehydrogenase GBrowse link multiple interactions ISO 2 214,931,901 215,818,809 RGD:6480464 CTD
G Dpyd dihydropyrimidine dehydrogenase GBrowse link decreases activity ISO 2 214,931,901 215,818,809 RGD:6480464 CTD
G Dpyd dihydropyrimidine dehydrogenase GBrowse link increases expression ISO 2 214,931,901 215,818,809 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link multiple interactions ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link increases response to substance ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Epo erythropoietin GBrowse link decreases response to substance EXP 12 19,551,768 19,555,208 RGD:6480464 CTD
G Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) GBrowse link multiple interactions ISO 10 87,219,157 87,242,919 RGD:6480464 CTD
G Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) GBrowse link multiple interactions ISO 10 87,219,157 87,242,919 RGD:6480464 CTD
G Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) GBrowse link increases response to substance ISO 10 87,219,157 87,242,919 RGD:6480464 CTD
G F2r coagulation factor II (thrombin) receptor GBrowse link decreases response to substance ISO 2 25,985,800 25,989,072 RGD:6480464 CTD
G Fas Fas (TNF receptor superfamily, member 6) GBrowse link increases expression ISO 1 238,259,443 238,274,745 RGD:6480464 CTD
G Fas Fas (TNF receptor superfamily, member 6) GBrowse link increases expression ISO 1 238,259,443 238,274,745 RGD:6480464 CTD
G Fas Fas (TNF receptor superfamily, member 6) GBrowse link increases expression ISO 1 238,259,443 238,274,745 RGD:6480464 CTD
G Fgf2 fibroblast growth factor 2 GBrowse link multiple interactions ISO 2 123,893,314 123,947,136 RGD:6480464 CTD
G Gadd45a growth arrest and DNA-damage-inducible, alpha GBrowse link multiple interactions ISO 4 96,649,941 96,652,243 RGD:6480464 CTD
G Gadd45a growth arrest and DNA-damage-inducible, alpha GBrowse link increases response to substance ISO 4 96,649,941 96,652,243 RGD:6480464 CTD
G Gapdh glyceraldehyde-3-phosphate dehydrogenase GBrowse link multiple interactions ISO 4 161,282,215 161,286,090 RGD:6480464 CTD
G Gstp1 glutathione S-transferase pi 1 GBrowse link increases response to substance ISO 1 206,627,398 206,629,866 RGD:6480464 CTD
G H2afx H2A histone family, member X GBrowse link multiple interactions ISO 8 47,312,609 47,313,938 RGD:6480464 CTD
G H2afx H2A histone family, member X GBrowse link increases expression ISO 8 47,312,609 47,313,938 RGD:6480464 CTD
G Hras Harvey rat sarcoma virus oncogene GBrowse link multiple interactions ISO 1 201,385,705 201,388,987 RGD:6480464 CTD
G Idh2 isocitrate dehydrogenase 2 (NADP+), mitochondrial GBrowse link multiple interactions ISO 1 135,876,052 135,895,373 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link increases expression ISO 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link increases expression EXP 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link increases expression ISO 4 456,799 461,376 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link increases expression ISO 4 456,799 461,376 RGD:6480464 CTD
G Jun jun proto-oncogene GBrowse link increases phosphorylation ISO 5 115,358,166 115,361,259 RGD:6480464 CTD
G Jun jun proto-oncogene GBrowse link multiple interactions ISO 5 115,358,166 115,361,259 RGD:6480464 CTD
G Kif12 kinesin family member 12 GBrowse link decreases response to substance ISO 5 80,146,349 80,152,996 RGD:6480464 CTD
G Kif5a kinesin family member 5A GBrowse link decreases response to substance ISO 7 67,183,575 67,220,766 RGD:6480464 CTD
G Kifc3 kinesin family member C3 GBrowse link decreases response to substance ISO 19 10,335,789 10,354,364 RGD:6480464 CTD
G Krt18 keratin 18 increases expression ISO RGD:6480464 CTD
G Krt18 keratin 18 increases metabolic processing ISO RGD:6480464 CTD
G Ldha lactate dehydrogenase A GBrowse link multiple interactions ISO 1 97,403,077 97,412,547 RGD:6480464 CTD
G Mad2l1 MAD2 mitotic arrest deficient-like 1 (yeast) GBrowse link affects response to substance ISO 4 96,380,039 96,386,042 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link increases phosphorylation ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link increases phosphorylation ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mcam melanoma cell adhesion molecule GBrowse link decreases response to substance ISO 8 47,105,632 47,127,936 RGD:6480464 CTD
G Mcl1 myeloid cell leukemia sequence 1 increases expression ISO RGD:6480464 CTD
G Mcl1 myeloid cell leukemia sequence 1 multiple interactions ISO RGD:6480464 CTD
G Mcm2 minichromosome maintenance complex component 2 GBrowse link multiple interactions ISO 4 122,977,522 122,991,934 RGD:6480464 CTD
G Mdm2 p53 E3 ubiquitin protein ligase GBrowse link increases expression ISO 7 56,996,694 57,020,926 RGD:6480464 CTD
G Mdm2 p53 E3 ubiquitin protein ligase GBrowse link increases expression ISO 7 56,996,694 57,020,926 RGD:6480464 CTD
G Mmp9 matrix metallopeptidase 9 GBrowse link multiple interactions ISO 3 155,985,473 155,993,433 RGD:6480464 CTD
G Nppb natriuretic peptide B GBrowse link increases expression ISO 5 165,062,348 165,063,650 RGD:6480464 CTD
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 GBrowse link multiple interactions ISO 11 64,239,918 64,276,702 RGD:6480464 CTD
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 GBrowse link increases activity ISO 11 64,239,918 64,276,702 RGD:6480464 CTD
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 GBrowse link multiple interactions ISO 11 64,239,918 64,276,702 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link multiple interactions ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link multiple interactions ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link multiple interactions ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link multiple interactions ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link increases cleavage ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link increases cleavage ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link increases cleavage ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link increases cleavage ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link increases cleavage ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link increases cleavage ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link increases cleavage ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Pgr progesterone receptor GBrowse link decreases expression ISO 8 5,784,717 5,845,901 RGD:6480464 CTD
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) GBrowse link multiple interactions ISO 13 64,135,729 64,280,815 RGD:6480464 CTD
G Pomc proopiomelanocortin GBrowse link increases expression EXP 6 26,931,969 26,937,789 RGD:6480464 CTD
G Pomc proopiomelanocortin GBrowse link multiple interactions EXP 6 26,931,969 26,937,789 RGD:6480464 CTD
G Por P450 (cytochrome) oxidoreductase GBrowse link increases response to substance ISO 12 22,078,629 22,097,301 RGD:6480464 CTD
G Pparg peroxisome proliferator-activated receptor gamma GBrowse link multiple interactions ISO 4 151,492,220 151,617,331 RGD:6480464 CTD
G Psip1 PC4 and SFRS1 interacting protein 1 GBrowse link increases cleavage ISO 5 102,304,948 102,336,608 RGD:6480464 CTD
G Ptges prostaglandin E synthase GBrowse link multiple interactions ISO 3 9,946,194 9,957,538 RGD:6480464 CTD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link increases expression ISO 13 64,427,288 64,432,978 RGD:6480464 CTD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link increases expression EXP 13 64,427,288 64,432,978 RGD:6480464 CTD
G Ptk2 protein tyrosine kinase 2 GBrowse link increases cleavage ISO 7 110,933,298 111,084,554 RGD:6480464 CTD
G Rad50 RAD50 homolog (S. cerevisiae) GBrowse link multiple interactions ISO 10 39,112,733 39,164,694 RGD:6480464 CTD
G Raf1 v-raf-leukemia viral oncogene 1 GBrowse link increases expression ISO 4 151,752,583 151,775,609 RGD:6480464 CTD
G Rb1 retinoblastoma 1 GBrowse link multiple interactions ISO 15 53,828,881 53,962,099 RGD:6480464 CTD
G Rgs10 regulator of G-protein signaling 10 GBrowse link increases response to substance ISO 1 187,622,488 187,664,295 RGD:6480464 CTD
G Rgs17 regulator of G-protein signaling 17 GBrowse link increases response to substance ISO 1 36,523,685 36,623,005 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link decreases expression ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link decreases expression ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b GBrowse link multiple interactions ISO 15 50,138,439 50,163,254 RGD:6480464 CTD
G Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b GBrowse link increases expression ISO 15 50,138,439 50,163,254 RGD:6480464 CTD
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 GBrowse link multiple interactions ISO 2 113,204,303 113,221,550 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link multiple interactions ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link decreases expression ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases expression ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link decreases ubiquitination ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases expression ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases ubiquitination ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link multiple interactions ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link multiple interactions ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link multiple interactions ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases expression ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases expression ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases expression ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases expression ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link decreases response to substance ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link multiple interactions ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases expression ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tubb5 tubulin, beta 5 class I GBrowse link increases expression ISO 20 3,060,224 3,090,776 RGD:6480464 CTD
G Tubb5 tubulin, beta 5 class I GBrowse link increases response to substance ISO 20 3,060,224 3,090,776 RGD:6480464 CTD
G Tubb5 tubulin, beta 5 class I GBrowse link multiple interactions ISO 20 3,060,224 3,090,776 RGD:6480464 CTD
G Tubb5 tubulin, beta 5 class I GBrowse link decreases response to substance ISO 20 3,060,224 3,090,776 RGD:6480464 CTD
G Tyms thymidylate synthetase GBrowse link multiple interactions ISO 9 112,604,912 112,617,706 RGD:6480464 CTD
G Tyms thymidylate synthetase GBrowse link decreases expression ISO 9 112,604,912 112,617,706 RGD:6480464 CTD
G Tyms thymidylate synthetase GBrowse link multiple interactions ISO 9 112,604,912 112,617,706 RGD:6480464 CTD
G Umps uridine monophosphate synthetase GBrowse link multiple interactions ISO 11 68,619,835 68,630,244 RGD:6480464 CTD
G Umps uridine monophosphate synthetase GBrowse link increases expression ISO 11 68,619,835 68,630,244 RGD:6480464 CTD
G Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 GBrowse link multiple interactions ISO 17 40,429,806 40,434,083 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link multiple interactions ISO 9 10,520,730 10,536,071 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link multiple interactions ISO 9 10,520,730 10,536,071 RGD:6480464 CTD
G Xiap X-linked inhibitor of apoptosis GBrowse link decreases expression ISO X 3,011,520 3,047,798 RGD:6480464 CTD
G Xiap X-linked inhibitor of apoptosis GBrowse link decreases response to substance ISO X 3,011,520 3,047,798 RGD:6480464 CTD
G Xiap X-linked inhibitor of apoptosis GBrowse link decreases expression ISO X 3,011,520 3,047,798 RGD:6480464 CTD
G Xrcc5 X-ray repair complementing defective repair in Chinese hamster cells 5 GBrowse link multiple interactions ISO 9 71,472,459 71,581,936 RGD:6480464 CTD
G Xrcc6 X-ray repair complementing defective repair in Chinese hamster cells 6 GBrowse link multiple interactions ISO 7 120,401,944 120,422,923 RGD:6480464 CTD
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 492507
    role 482196
      application 245130
        pharmaceutical 173979
          drug 173776
            antineoplastic agent 62937
              docetaxel anhydrous 242
                docetaxel trihydrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 492507
    subatomic particle 491470
      composite particle 491470
        hadron 491470
          baryon 491470
            nucleon 491470
              atomic nucleus 491470
                atom 491470
                  main group element atom 461139
                    main group molecular entity 456059
                      s-block molecular entity 310120
                        hydrogen molecular entity 307366
                          hydrides 192514
                            organic hydride 118081
                              organic fundamental parent 118081
                                hydrocarbon 70694
                                  terpene 15659
                                    diterpene 13755
                                      diterpenoid 13746
                                        tetracyclic diterpenoid 1388
                                          docetaxel anhydrous 242
                                            docetaxel trihydrate 0
paths to the root

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