ONTOLOGY REPORT - ANNOTATIONS
Term: paclitaxel
Accession: CHEBI:45863
browse the term
Definition: A tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. Note that the use of the former generic name 'taxol' is now limited, as Taxol is a registered trade mark.
Synonyms: exact_synonym: 4alpha,10beta-bis(acetyloxy)-13alpha-[(2S,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyloxy]-1,7beta-dihydroxy-9-oxo-5beta,20-epoxytax-11-en-2alpha-yl benzoate
related_synonym: (2aR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha R*,betaS*),11alpha,12alpha,12balpha))-beta-(Benzoylamino)-alpha-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester; 5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine; C47H51NO14; InChI=1S/C47H51NO14/c1-25-31(60-43(56)36(52)35(28-16-10-7-11-17-28)48-41(54)29-18-12-8-13-19-29)23-47(57)40(61-42(55)30-20-14-9-15-21-30)38-45(6,32(51)22-33-46(38,24-58-33)62-27(3)50)39(53)37(59-26(2)49)34(25)44(47,4)5/h7-21,31-33,35-38,40,51-52,57H,22-24H2,1-6H3,(H,48,54)/t31-,32-,33+,35-,36+,37+,38-,40-,45+,46-,47+/m0/s1; InChIKey=RCINICONZNJXQF-MZXODVADSA-N; TAXOL; Taxol A; [H][C@]12[C@H](OC(=O)c3ccccc3)[C@]3(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)c4ccccc4)c4ccccc4)C(C)=C([C@@H](OC(C)=O)C(=O)[C@]1(C)[C@@H](O)C[C@H]1OC[C@@]21OC(C)=O)C3(C)C
alt_id: CHEBI:45862; CHEBI:7887
xref_casrn: 33069-62-4
xref: ChEMBL:108062 "ChEMBL COMPOUND"; ChemIDplus:33069-62-4 "CAS Registry Number"; DrugBank:DB01229 "DrugBank"; KEGG COMPOUND:33069-62-4 "CAS Registry Number"; KEGG COMPOUND:C07394 "KEGG COMPOUND"; KEGG DRUG:D00491 "KEGG DRUG"
xref_mesh: MESH:D017239
xref: PDBeChem:TA1 "PDBeChem"; Wikipedia:Paclitaxel "Wikipedia"
paclitaxel
G
Abca5
ATP-binding cassette, subfamily A (ABC1), member 5
increases expression
ISO
10
99,724,778
99,793,593
RGD:6480464
CTD
G
Abca7
ATP-binding cassette, subfamily A (ABC1), member 7
increases expression
ISO
7
11,203,983
11,222,960
RGD:6480464
CTD
G
Abcb11
ATP-binding cassette, subfamily B (MDR/TAP), member 11
decreases activity
ISO
RGD:6480464
CTD
G
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
affects metabolic processing
ISO
4
21,709,855
21,796,628
RGD:6480464
CTD
G
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
affects response to substance
ISO
4
21,709,855
21,796,628
RGD:6480464
CTD
G
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
increases response to substance
ISO
4
21,709,855
21,796,628
RGD:6480464
CTD
G
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
decreases response to substance
ISO
4
21,709,855
21,796,628
RGD:6480464
CTD
G
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
multiple interactions
ISO
4
21,709,855
21,796,628
RGD:6480464
CTD
G
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
decreases uptake
ISO
4
21,709,855
21,796,628
RGD:6480464
CTD
G
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
decreases response to substance
ISO
4
21,709,855
21,796,628
RGD:6480464
CTD
G
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
multiple interactions
ISO
4
21,709,855
21,796,628
RGD:6480464
CTD
G
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
multiple interactions
ISO
4
21,709,855
21,796,628
RGD:6480464
CTD
G
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
multiple interactions
ISO
4
21,709,855
21,796,628
RGD:6480464
CTD
G
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
increases expression
ISO
4
21,709,855
21,796,628
RGD:6480464
CTD
G
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
increases expression
ISO
4
21,709,855
21,796,628
RGD:6480464
CTD
G
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
multiple interactions
ISO
4
21,709,855
21,796,628
RGD:6480464
CTD
G
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
decreases response to substance
ISO
4
21,709,855
21,796,628
RGD:6480464
CTD
G
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
increases expression
ISO
4
21,709,855
21,796,628
RGD:6480464
CTD
G
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
increases expression
ISO
4
21,709,855
21,796,628
RGD:6480464
CTD
G
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
decreases response to substance
ISO
4
21,709,855
21,796,628
RGD:6480464
CTD
G
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
increases expression
ISO
4
21,709,855
21,796,628
RGD:6480464
CTD
G
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
increases expression
ISO
4
21,709,855
21,796,628
RGD:6480464
CTD
G
Abcb4
ATP-binding cassette, subfamily B (MDR/TAP), member 4
decreases response to substance
ISO
4
21,946,274
22,004,328
RGD:6480464
CTD
G
Abcb6
ATP-binding cassette, subfamily B (MDR/TAP), member 6
decreases expression
ISO
9
74,454,805
74,463,083
RGD:6480464
CTD
G
Abcc1
ATP-binding cassette, subfamily C (CFTR/MRP), member 1
decreases response to substance
ISO
10
452,239
575,705
RGD:6480464
CTD
G
Abcc10
ATP-binding cassette, subfamily C (CFTR/MRP), member 10
increases expression
ISO
9
10,219,822
10,239,734
RGD:6480464
CTD
G
Abcc2
ATP-binding cassette, subfamily C (CFTR/MRP), member 2
affects response to substance
ISO
RGD:6480464
CTD
G
Abcc2
ATP-binding cassette, subfamily C (CFTR/MRP), member 2
affects transport
ISO
RGD:6480464
CTD
G
Abcc2
ATP-binding cassette, subfamily C (CFTR/MRP), member 2
decreases response to substance
ISO
RGD:6480464
CTD
G
Abcc2
ATP-binding cassette, subfamily C (CFTR/MRP), member 2
increases export
ISO
RGD:6480464
CTD
G
Abcc2
ATP-binding cassette, subfamily C (CFTR/MRP), member 2
multiple interactions
ISO
RGD:6480464
CTD
G
Abcc2
ATP-binding cassette, subfamily C (CFTR/MRP), member 2
affects expression
ISO
RGD:6480464
CTD
G
Abcc2
ATP-binding cassette, subfamily C (CFTR/MRP), member 2
multiple interactions
ISO
RGD:6480464
CTD
G
Abcc3
ATP-binding cassette, subfamily C (CFTR/MRP), member 3
increases expression
ISO
10
82,986,552
83,030,799
RGD:6480464
CTD
G
Abcc4
ATP-binding cassette, subfamily C (CFTR/MRP), member 4
increases expression
EXP
15
103,384,848
103,611,238
RGD:6480464
CTD
G
Abcc5
ATP-binding cassette, subfamily C (CFTR/MRP), member 5
increases expression
ISO
11
82,714,334
82,809,354
RGD:6480464
CTD
G
Abcg2
ATP-binding cassette, subfamily G (WHITE), member 2
decreases expression
ISO
4
87,502,584
87,560,017
RGD:6480464
CTD
G
Abcg2
ATP-binding cassette, subfamily G (WHITE), member 2
multiple interactions
ISO
4
87,502,584
87,560,017
RGD:6480464
CTD
G
Abcg2
ATP-binding cassette, subfamily G (WHITE), member 2
multiple interactions
ISO
4
87,502,584
87,560,017
RGD:6480464
CTD
G
Acadl
acyl-CoA dehydrogenase, long chain
decreases expression
ISO
9
65,613,130
65,651,775
RGD:6480464
CTD
G
Adcy6
adenylate cyclase 6
decreases expression
ISO
7
137,339,933
137,360,020
RGD:6480464
CTD
G
Add3
adducin 3 (gamma)
affects response to substance
ISO
1
259,347,673
259,455,407
RGD:6480464
CTD
G
Adss
adenylosuccinate synthase
decreases expression
ISO
13
93,681,036
93,711,373
RGD:6480464
CTD
G
Aifm1
apoptosis-inducing factor, mitochondrion-associated 1
multiple interactions
ISO
X
134,868,878
134,908,166
RGD:6480464
CTD
G
Akr1b1
aldo-keto reductase family 1, member B1 (aldose reductase)
increases response to substance
ISO
4
61,645,438
61,659,530
RGD:6480464
CTD
G
Akr1b7
aldo-keto reductase family 1, member B7
increases expression
EXP
4
61,794,352
61,806,916
RGD:6480464
CTD
G
Akr1c2
aldo-keto reductase family 1, member C2
increases response to substance
ISO
17
77,034,737
77,081,406
RGD:6480464
CTD
G
Akt1
v-akt murine thymoma viral oncogene homolog 1
multiple interactions
ISO
6
137,640,482
137,657,552
RGD:6480464
CTD
G
Akt1
v-akt murine thymoma viral oncogene homolog 1
multiple interactions
ISO
6
137,640,482
137,657,552
RGD:6480464
CTD
G
Akt1
v-akt murine thymoma viral oncogene homolog 1
affects response to substance
ISO
6
137,640,482
137,657,552
RGD:6480464
CTD
G
Akt1
v-akt murine thymoma viral oncogene homolog 1
decreases phosphorylation
ISO
6
137,640,482
137,657,552
RGD:6480464
CTD
G
Akt1
v-akt murine thymoma viral oncogene homolog 1
decreases response to substance
ISO
6
137,640,482
137,657,552
RGD:6480464
CTD
G
Akt1
v-akt murine thymoma viral oncogene homolog 1
increases activity
ISO
6
137,640,482
137,657,552
RGD:6480464
CTD
G
Akt1
v-akt murine thymoma viral oncogene homolog 1
multiple interactions
ISO
6
137,640,482
137,657,552
RGD:6480464
CTD
G
Akt2
v-akt murine thymoma viral oncogene homolog 2
affects response to substance
ISO
1
82,686,233
82,726,544
RGD:6480464
CTD
G
Akt2
v-akt murine thymoma viral oncogene homolog 2
increases phosphorylation
ISO
1
82,686,233
82,726,544
RGD:6480464
CTD
G
Akt3
v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
affects response to substance
ISO
13
92,802,390
93,110,704
RGD:6480464
CTD
G
Aldh9a1
aldehyde dehydrogenase 9 family, member A1
increases expression
ISO
13
83,017,312
83,034,047
RGD:6480464
CTD
G
Alg8
ALG8, alpha-1,3-glucosyltransferase
affects response to substance
ISO
1
154,607,442
154,628,227
RGD:6480464
CTD
G
Amacr
alpha-methylacyl-CoA racemase
increases expression
EXP
2
60,332,292
60,344,326
RGD:6480464
CTD
G
Amfr
autocrine motility factor receptor, E3 ubiquitin protein ligase
multiple interactions
ISO
19
11,434,553
11,467,592
RGD:6480464
CTD
G
Anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
affects response to substance
ISO
8
66,488,188
66,523,421
RGD:6480464
CTD
G
Anxa1
annexin A1
increases response to substance
ISO
1
223,478,436
223,494,455
RGD:6480464
CTD
G
Anxa4
annexin A4
decreases response to substance
ISO
4
120,889,617
120,947,662
RGD:6480464
CTD
G
Anxa8
annexin A8
increases response to substance
ISO
16
9,715,644
9,730,584
RGD:6480464
CTD
G
Aox1
aldehyde oxidase 1
affects response to substance
ISO
9
56,693,698
56,774,115
RGD:6480464
CTD
G
Apaf1
apoptotic peptidase activating factor 1
increases expression
ISO
7
27,932,908
28,020,533
RGD:6480464
CTD
G
Apaf1
apoptotic peptidase activating factor 1
multiple interactions
ISO
7
27,932,908
28,020,533
RGD:6480464
CTD
G
Apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
increases expression
EXP
17
96,476,962
96,527,635
RGD:6480464
CTD
G
Aplp2
amyloid beta (A4) precursor-like protein 2
affects response to substance
ISO
RGD:6480464
CTD
G
Apod
apolipoprotein D
increases expression
ISO
RGD:6480464
CTD
G
Areg
amphiregulin
increases expression
ISO
14
18,466,313
18,475,571
RGD:6480464
CTD
G
Arf3
ADP-ribosylation factor 3
affects response to substance
ISO
7
137,505,200
137,510,262
RGD:6480464
CTD
G
Arhgdia
Rho GDP dissociation inhibitor (GDI) alpha
multiple interactions
ISO
10
109,967,771
109,971,260
RGD:6480464
CTD
G
Arhgdia
Rho GDP dissociation inhibitor (GDI) alpha
affects response to substance
ISO
10
109,967,771
109,971,260
RGD:6480464
CTD
G
Arr3
arrestin 3, retinal (X-arrestin)
decreases response to substance
ISO
X
88,602,380
88,614,721
RGD:6480464
CTD
G
Aspm
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
increases expression
ISO
13
52,811,658
52,860,925
RGD:6480464
CTD
G
Atf3
activating transcription factor 3
multiple interactions
EXP
13
107,191,622
107,223,850
RGD:6480464
CTD
G
Atf3
activating transcription factor 3
increases expression
EXP
13
107,191,622
107,223,850
RGD:6480464
CTD
G
Atf3
activating transcription factor 3
increases expression
EXP
13
107,191,622
107,223,850
RGD:6480464
CTD
G
Atf3
activating transcription factor 3
increases expression
EXP
13
107,191,622
107,223,850
RGD:6480464
CTD
G
Atf5
activating transcription factor 5
decreases expression
ISO
1
95,284,505
95,286,786
RGD:6480464
CTD
G
Atp2a2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
increases expression
EXP
12
35,266,600
35,316,237
RGD:6480464
CTD
G
Atp6v1a
ATPase, H+ transporting, lysosomal V1 subunit A
affects response to substance
ISO
11
58,127,307
58,180,225
RGD:6480464
CTD
G
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
increases expression
ISO
X
94,192,540
94,249,776
RGD:6480464
CTD
G
Aurka
aurora kinase A
increases expression
ISO
3
163,270,479
163,284,506
RGD:6480464
CTD
G
Axl
Axl receptor tyrosine kinase
increases response to substance
ISO
1
80,964,751
80,994,300
RGD:6480464
CTD
G
Bad
BCL2-associated agonist of cell death
increases expression
ISO
1
209,617,373
209,626,292
RGD:6480464
CTD
G
Bad
BCL2-associated agonist of cell death
multiple interactions
ISO
1
209,617,373
209,626,292
RGD:6480464
CTD
G
Bak1
BCL2-antagonist/killer 1
affects expression
ISO
20
5,255,954
5,264,593
RGD:6480464
CTD
G
Bak1
BCL2-antagonist/killer 1
increases expression
ISO
20
5,255,954
5,264,593
RGD:6480464
CTD
G
Bak1
BCL2-antagonist/killer 1
multiple interactions
ISO
20
5,255,954
5,264,593
RGD:6480464
CTD
G
Bax
Bcl2-associated X protein
multiple interactions
ISO
1
95,933,023
95,938,176
RGD:6480464
CTD
G
Bax
Bcl2-associated X protein
increases expression
ISO
1
95,933,023
95,938,176
RGD:6480464
CTD
G
Bax
Bcl2-associated X protein
increases expression
ISO
1
95,933,023
95,938,176
RGD:6480464
CTD
G
Bax
Bcl2-associated X protein
increases expression
ISO
1
95,933,023
95,938,176
RGD:6480464
CTD
G
Bax
Bcl2-associated X protein
multiple interactions
ISO
1
95,933,023
95,938,176
RGD:6480464
CTD
G
Bax
Bcl2-associated X protein
multiple interactions
ISO
1
95,933,023
95,938,176
RGD:6480464
CTD
G
Bax
Bcl2-associated X protein
affects response to substance
ISO
1
95,933,023
95,938,176
RGD:6480464
CTD
G
Bax
Bcl2-associated X protein
increases expression
ISO
1
95,933,023
95,938,176
RGD:6480464
CTD
G
Bax
Bcl2-associated X protein
multiple interactions
ISO
1
95,933,023
95,938,176
RGD:6480464
CTD
G
Bax
Bcl2-associated X protein
increases expression
ISO
1
95,933,023
95,938,176
RGD:6480464
CTD
G
Bax
Bcl2-associated X protein
increases expression
ISO
1
95,933,023
95,938,176
RGD:6480464
CTD
G
Bbc3
Bcl-2 binding component 3
increases response to substance
ISO
RGD:6480464
CTD
G
Bbc3
Bcl-2 binding component 3
increases expression
ISO
RGD:6480464
CTD
G
Bbs4
Bardet-Biedl syndrome 4
multiple interactions
ISO
8
63,153,456
63,189,904
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
multiple interactions
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
multiple interactions
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
decreases response to substance
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
decreases response to substance
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
multiple interactions
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
multiple interactions
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
multiple interactions
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
multiple interactions
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
multiple interactions
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
multiple interactions
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
affects localization
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
multiple interactions
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
decreases activity
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
decreases degradation
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
multiple interactions
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
decreases expression
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
decreases expression
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
increases cleavage
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
increases phosphorylation
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
multiple interactions
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
multiple interactions
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
multiple interactions
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
multiple interactions
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
decreases expression
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
increases phosphorylation
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
decreases expression
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2
B-cell CLL/lymphoma 2
increases phosphorylation
ISO
13
12,730,736
12,905,108
RGD:6480464
CTD
G
Bcl2l1
Bcl2-like 1
decreases response to substance
ISO
3
143,129,087
143,180,199
RGD:6480464
CTD
G
Bcl2l1
Bcl2-like 1
multiple interactions
ISO
3
143,129,087
143,180,199
RGD:6480464
CTD
G
Bcl2l1
Bcl2-like 1
multiple interactions
ISO
3
143,129,087
143,180,199
RGD:6480464
CTD
G
Bcl2l1
Bcl2-like 1
multiple interactions
ISO
3
143,129,087
143,180,199
RGD:6480464
CTD
G
Bcl2l1
Bcl2-like 1
decreases expression
ISO
3
143,129,087
143,180,199
RGD:6480464
CTD
G
Bcl2l1
Bcl2-like 1
decreases expression
ISO
3
143,129,087
143,180,199
RGD:6480464
CTD
G
Bcl2l1
Bcl2-like 1
increases expression
ISO
3
143,129,087
143,180,199
RGD:6480464
CTD
G
Bcl2l1
Bcl2-like 1
increases phosphorylation
ISO
3
143,129,087
143,180,199
RGD:6480464
CTD
G
Bcl2l1
Bcl2-like 1
decreases response to substance
ISO
3
143,129,087
143,180,199
RGD:6480464
CTD
G
Bcl2l1
Bcl2-like 1
decreases expression
ISO
3
143,129,087
143,180,199
RGD:6480464
CTD
G
Bcl2l1
Bcl2-like 1
decreases response to substance
ISO
3
143,129,087
143,180,199
RGD:6480464
CTD
G
Bcl2l11
BCL2-like 11 (apoptosis facilitator)
affects response to substance
ISO
3
115,692,323
115,722,701
RGD:6480464
CTD
G
Bcl6b
B-cell CLL/lymphoma 6, member B
increases expression
EXP
10
57,063,162
57,068,306
RGD:6480464
CTD
G
Becn1
beclin 1, autophagy related
multiple interactions
ISO
10
90,317,957
90,333,329
RGD:6480464
CTD
G
Bgn
biglycan
affects response to substance
ISO
X
159,380,557
159,393,409
RGD:6480464
CTD
G
Bid
BH3 interacting domain death agonist
increases expression
ISO
4
157,296,383
157,318,481
RGD:6480464
CTD
G
Bid
BH3 interacting domain death agonist
increases cleavage
ISO
4
157,296,383
157,318,481
RGD:6480464
CTD
G
Bid
BH3 interacting domain death agonist
multiple interactions
ISO
4
157,296,383
157,318,481
RGD:6480464
CTD
G
Bin1
bridging integrator 1
increases expression
ISO
18
24,813,407
24,872,852
RGD:6480464
CTD
G
Bin3
bridging integrator 3
decreases expression
ISO
15
50,519,884
50,539,242
RGD:6480464
CTD
G
Birc2
baculoviral IAP repeat-containing 2
affects response to substance
ISO
8
4,649,559
4,667,733
RGD:6480464
CTD
G
Birc2
baculoviral IAP repeat-containing 2
multiple interactions
ISO
8
4,649,559
4,667,733
RGD:6480464
CTD
G
Birc2
baculoviral IAP repeat-containing 2
decreases expression
ISO
8
4,649,559
4,667,733
RGD:6480464
CTD
G
Birc2
baculoviral IAP repeat-containing 2
multiple interactions
ISO
8
4,649,559
4,667,733
RGD:6480464
CTD
G
Birc2
baculoviral IAP repeat-containing 2
multiple interactions
ISO
8
4,649,559
4,667,733
RGD:6480464
CTD
G
Birc2
baculoviral IAP repeat-containing 2
decreases expression
ISO
8
4,649,559
4,667,733
RGD:6480464
CTD
G
Birc2
baculoviral IAP repeat-containing 2
decreases expression
ISO
8
4,649,559
4,667,733
RGD:6480464
CTD
G
Birc3
baculoviral IAP repeat-containing 3
multiple interactions
ISO
8
4,682,202
4,696,856
RGD:6480464
CTD
G
Birc3
baculoviral IAP repeat-containing 3
decreases expression
ISO
8
4,682,202
4,696,856
RGD:6480464
CTD
G
Birc3
baculoviral IAP repeat-containing 3
multiple interactions
ISO
8
4,682,202
4,696,856
RGD:6480464
CTD
G
Birc3
baculoviral IAP repeat-containing 3
decreases expression
ISO
8
4,682,202
4,696,856
RGD:6480464
CTD
G
Birc3
baculoviral IAP repeat-containing 3
decreases expression
ISO
8
4,682,202
4,696,856
RGD:6480464
CTD
G
Birc3
baculoviral IAP repeat-containing 3
multiple interactions
ISO
8
4,682,202
4,696,856
RGD:6480464
CTD
G
Birc5
baculoviral IAP repeat-containing 5
multiple interactions
ISO
RGD:6480464
CTD
G
Birc5
baculoviral IAP repeat-containing 5
multiple interactions
ISO
RGD:6480464
CTD
G
Birc5
baculoviral IAP repeat-containing 5
multiple interactions
ISO
RGD:6480464
CTD
G
Birc5
baculoviral IAP repeat-containing 5
decreases response to substance
ISO
RGD:6480464
CTD
G
Birc5
baculoviral IAP repeat-containing 5
decreases expression
ISO
RGD:6480464
CTD
G
Birc5
baculoviral IAP repeat-containing 5
decreases expression
ISO
RGD:6480464
CTD
G
Birc5
baculoviral IAP repeat-containing 5
decreases expression
ISO
RGD:6480464
CTD
G
Birc5
baculoviral IAP repeat-containing 5
increases expression
ISO
RGD:6480464
CTD
G
Birc5
baculoviral IAP repeat-containing 5
multiple interactions
ISO
RGD:6480464
CTD
G
Birc5
baculoviral IAP repeat-containing 5
increases expression
ISO
RGD:6480464
CTD
G
Birc5
baculoviral IAP repeat-containing 5
multiple interactions
ISO
RGD:6480464
CTD
G
Birc5
baculoviral IAP repeat-containing 5
decreases expression
ISO
RGD:6480464
CTD
G
Birc5
baculoviral IAP repeat-containing 5
increases expression
ISO
RGD:6480464
CTD
G
Birc5
baculoviral IAP repeat-containing 5
decreases expression
ISO
RGD:6480464
CTD
G
Birc5
baculoviral IAP repeat-containing 5
increases expression
ISO
RGD:6480464
CTD
G
Bmi1
Bmi1 polycomb ring finger oncogene
decreases expression
ISO
17
92,784,216
92,787,947
RGD:6480464
CTD
G
Bmp7
bone morphogenetic protein 7
increases response to substance
ISO
3
163,723,429
163,799,567
RGD:6480464
CTD
G
Brca1
breast cancer 1, early onset
decreases expression
ISO
10
90,513,630
90,572,676
RGD:6480464
CTD
G
Btg2
BTG family, member 2
decreases expression
EXP
13
47,026,986
47,030,745
RGD:6480464
CTD
G
Btg3
BTG family, member 3
multiple interactions
ISO
11
17,241,627
17,257,740
RGD:6480464
CTD
G
Btg3
BTG family, member 3
increases expression
ISO
11
17,241,627
17,257,740
RGD:6480464
CTD
G
Bub1b
BUB1 mitotic checkpoint serine/threonine kinase B
affects response to substance
ISO
3
105,063,018
105,116,145
RGD:6480464
CTD
G
Bub1b
BUB1 mitotic checkpoint serine/threonine kinase B
multiple interactions
ISO
3
105,063,018
105,116,145
RGD:6480464
CTD
G
Bub3
budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae)
increases expression
ISO
1
191,128,891
191,139,401
RGD:6480464
CTD
G
C1qa
complement component 1, q subcomponent, A chain
increases expression
EXP
5
155,662,333
155,665,180
RGD:6480464
CTD
G
C1qb
complement component 1, q subcomponent, B chain
increases expression
EXP
5
155,647,524
155,653,074
RGD:6480464
CTD
G
C1qc
complement component 1, q subcomponent, C chain
increases expression
EXP
5
155,656,104
155,659,430
RGD:6480464
CTD
G
C1s
complement component 1, s subcomponent
increases expression
EXP
4
160,736,133
160,748,133
RGD:6480464
CTD
G
C3
complement component 3
increases expression
EXP
RGD:6480464
CTD
G
C4a
complement component 4A (Rodgers blood group)
increases expression
EXP
20
4,106,123
4,145,904
RGD:6480464
CTD
G
Cacna2d1
calcium channel, voltage-dependent, alpha2/delta subunit 1
increases expression
ISO
4
15,139,881
15,566,740
RGD:6480464
CTD
G
Cacna2d1
calcium channel, voltage-dependent, alpha2/delta subunit 1
increases expression
ISO
4
15,139,881
15,566,740
RGD:6480464
CTD
G
Calca
calcitonin-related polypeptide alpha
multiple interactions
EXP
1
172,686,168
172,691,061
RGD:6480464
CTD
G
Calca
calcitonin-related polypeptide alpha
increases expression
EXP
1
172,686,168
172,691,061
RGD:6480464
CTD
G
Camk2b
calcium/calmodulin-dependent protein kinase II beta
affects response to substance
ISO
14
86,632,686
86,721,281
RGD:6480464
CTD
G
Caprin1
cell cycle associated protein 1
decreases expression
ISO
3
89,062,097
89,093,093
RGD:6480464
CTD
G
Car12
carbonic anyhydrase 12
multiple interactions
ISO
8
71,017,732
71,070,729
RGD:6480464
CTD
G
Casp12
caspase 12
decreases expression
ISO
8
2,082,933
2,110,511
RGD:6480464
CTD
G
Casp12
caspase 12
increases expression
ISO
8
2,082,933
2,110,511
RGD:6480464
CTD
G
Casp12
caspase 12
multiple interactions
ISO
8
2,082,933
2,110,511
RGD:6480464
CTD
G
Casp3
caspase 3
multiple interactions
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
multiple interactions
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
multiple interactions
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
multiple interactions
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
multiple interactions
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
multiple interactions
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
multiple interactions
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
multiple interactions
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
multiple interactions
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
increases activity
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
multiple interactions
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
multiple interactions
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
multiple interactions
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
increases cleavage
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
increases expression
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
increases expression
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
multiple interactions
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
increases expression
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
multiple interactions
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
multiple interactions
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
multiple interactions
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
multiple interactions
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
multiple interactions
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
multiple interactions
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
multiple interactions
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
increases expression
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
multiple interactions
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
multiple interactions
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
increases activity
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
increases cleavage
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp3
caspase 3
increases activity
ISO
16
48,944,226
48,962,420
RGD:6480464
CTD
G
Casp4
caspase 4, apoptosis-related cysteine peptidase
increases expression
ISO
8
2,038,626
2,075,722
RGD:6480464
CTD
G
Casp7
caspase 7
multiple interactions
ISO
1
262,689,300
262,721,591
RGD:6480464
CTD
G
Casp7
caspase 7
multiple interactions
ISO
1
262,689,300
262,721,591
RGD:6480464
CTD
G
Casp7
caspase 7
multiple interactions
ISO
1
262,689,300
262,721,591
RGD:6480464
CTD
G
Casp7
caspase 7
increases expression
ISO
1
262,689,300
262,721,591
RGD:6480464
CTD
G
Casp8
caspase 8
multiple interactions
ISO
9
57,389,353
57,437,803
RGD:6480464
CTD
G
Casp8
caspase 8
multiple interactions
ISO
9
57,389,353
57,437,803
RGD:6480464
CTD
G
Casp8
caspase 8
increases expression
ISO
9
57,389,353
57,437,803
RGD:6480464
CTD
G
Casp8
caspase 8
increases activity
ISO
9
57,389,353
57,437,803
RGD:6480464
CTD
G
Casp8
caspase 8
increases cleavage
ISO
9
57,389,353
57,437,803
RGD:6480464
CTD
G
Casp8
caspase 8
increases expression
ISO
9
57,389,353
57,437,803
RGD:6480464
CTD
G
Casp8
caspase 8
multiple interactions
ISO
9
57,389,353
57,437,803
RGD:6480464
CTD
G
Casp8
caspase 8
multiple interactions
ISO
9
57,389,353
57,437,803
RGD:6480464
CTD
G
Casp8
caspase 8
multiple interactions
ISO
9
57,389,353
57,437,803
RGD:6480464
CTD
G
Casp8
caspase 8
increases cleavage
ISO
9
57,389,353
57,437,803
RGD:6480464
CTD
G
Casp9
caspase 9, apoptosis-related cysteine peptidase
multiple interactions
ISO
5
160,704,234
160,721,796
RGD:6480464
CTD
G
Casp9
caspase 9, apoptosis-related cysteine peptidase
affects response to substance
ISO
5
160,704,234
160,721,796
RGD:6480464
CTD
G
Casp9
caspase 9, apoptosis-related cysteine peptidase
multiple interactions
ISO
5
160,704,234
160,721,796
RGD:6480464
CTD
G
Casp9
caspase 9, apoptosis-related cysteine peptidase
increases activity
ISO
5
160,704,234
160,721,796
RGD:6480464
CTD
G
Casp9
caspase 9, apoptosis-related cysteine peptidase
increases expression
ISO
5
160,704,234
160,721,796
RGD:6480464
CTD
G
Casp9
caspase 9, apoptosis-related cysteine peptidase
increases expression
ISO
5
160,704,234
160,721,796
RGD:6480464
CTD
G
Casp9
caspase 9, apoptosis-related cysteine peptidase
multiple interactions
ISO
5
160,704,234
160,721,796
RGD:6480464
CTD
G
Casp9
caspase 9, apoptosis-related cysteine peptidase
multiple interactions
ISO
5
160,704,234
160,721,796
RGD:6480464
CTD
G
Casp9
caspase 9, apoptosis-related cysteine peptidase
multiple interactions
ISO
5
160,704,234
160,721,796
RGD:6480464
CTD
G
Casp9
caspase 9, apoptosis-related cysteine peptidase
multiple interactions
ISO
5
160,704,234
160,721,796
RGD:6480464
CTD
G
Cat
catalase
affects response to substance
ISO
3
88,654,077
88,686,212
RGD:6480464
CTD
G
Cat
catalase
increases response to substance
ISO
3
88,654,077
88,686,212
RGD:6480464
CTD
G
Cav1
caveolin 1, caveolae protein
increases response to substance
ISO
4
42,956,102
42,989,057
RGD:6480464
CTD
G
Ccar1
cell division cycle and apoptosis regulator 1
increases expression
ISO
20
29,997,000
30,039,602
RGD:6480464
CTD
G
Ccl2
chemokine (C-C motif) ligand 2
increases response to substance
ISO
10
70,256,263
70,258,061
RGD:6480464
CTD
G
Ccl21
chemokine (C-C motif) ligand 21
increases expression
EXP
5
59,238,897
59,240,001
RGD:6480464
CTD
G
Ccnb1
cyclin B1
increases response to substance
ISO
2
31,574,600
31,581,784
RGD:6480464
CTD
G
Ccnb1
cyclin B1
multiple interactions
ISO
2
31,574,600
31,581,784
RGD:6480464
CTD
G
Ccnb1
cyclin B1
multiple interactions
ISO
2
31,574,600
31,581,784
RGD:6480464
CTD
G
Ccnb1
cyclin B1
multiple interactions
ISO
2
31,574,600
31,581,784
RGD:6480464
CTD
G
Ccnb1
cyclin B1
increases expression
ISO
2
31,574,600
31,581,784
RGD:6480464
CTD
G
Ccnb1
cyclin B1
multiple interactions
ISO
2
31,574,600
31,581,784
RGD:6480464
CTD
G
Ccnb2
cyclin B2
affects response to substance
ISO
8
74,892,108
74,906,181
RGD:6480464
CTD
G
Ccnd1
cyclin D1
multiple interactions
ISO
1
205,357,235
205,366,757
RGD:6480464
CTD
G
Ccne2
cyclin E2
decreases expression
ISO
5
25,032,748
25,044,509
RGD:6480464
CTD
G
Ccne2
cyclin E2
decreases expression
ISO
5
25,032,748
25,044,509
RGD:6480464
CTD
G
Ccng2
cyclin G2
increases expression
ISO
14
16,338,132
16,346,628
RGD:6480464
CTD
G
Ccnh
cyclin H
increases expression
ISO
2
14,179,894
14,200,704
RGD:6480464
CTD
G
Cd14
CD14 molecule
multiple interactions
ISO
18
29,374,593
29,376,190
RGD:6480464
CTD
G
Cd14
CD14 molecule
increases expression
EXP
18
29,374,593
29,376,190
RGD:6480464
CTD
G
Cd14
CD14 molecule
affects response to substance
ISO
18
29,374,593
29,376,190
RGD:6480464
CTD
G
Cd163
CD163 molecule
increases expression
EXP
4
160,394,833
160,428,208
RGD:6480464
CTD
G
Cd24
CD24 molecule
decreases expression
ISO
20
47,502,354
47,507,663
RGD:6480464
CTD
G
Cd274
CD274 molecule
increases expression
ISO
1
233,053,607
233,065,384
RGD:6480464
CTD
G
Cd36
CD36 molecule (thrombospondin receptor)
increases expression
EXP
4
13,471,878
13,525,620
RGD:6480464
CTD
G
Cd40lg
CD40 ligand
multiple interactions
ISO
X
141,925,019
141,937,183
RGD:6480464
CTD
G
Cd40lg
CD40 ligand
decreases response to substance
ISO
X
141,925,019
141,937,183
RGD:6480464
CTD
G
Cd46
CD46 molecule, complement regulatory protein
increases response to substance
ISO
13
110,972,812
111,003,407
RGD:6480464
CTD
G
Cd47
Cd47 molecule
decreases response to substance
ISO
11
52,098,355
52,158,169
RGD:6480464
CTD
G
Cd68
Cd68 molecule
increases expression
EXP
10
56,481,701
56,483,580
RGD:6480464
CTD
G
Cda
cytidine deaminase
affects response to substance
ISO
5
157,117,303
157,143,989
RGD:6480464
CTD
G
Cdc14b
cell division cycle 14B
decreases expression
ISO
17
6,371,204
6,454,460
RGD:6480464
CTD
G
Cdc20
cell division cycle 20
multiple interactions
ISO
5
138,913,180
138,916,744
RGD:6480464
CTD
G
Cdc25a
cell division cycle 25A
increases expression
ISO
8
114,237,704
114,255,971
RGD:6480464
CTD
G
Cdc25c
cell division cycle 25C
multiple interactions
ISO
18
27,206,537
27,225,811
RGD:6480464
CTD
G
Cdc25c
cell division cycle 25C
decreases expression
ISO
18
27,206,537
27,225,811
RGD:6480464
CTD
G
Cdc25c
cell division cycle 25C
multiple interactions
ISO
18
27,206,537
27,225,811
RGD:6480464
CTD
G
Cdc27
cell division cycle 27
multiple interactions
ISO
10
93,678,790
93,725,987
RGD:6480464
CTD
G
Cdc5l
cell division cycle 5-like
decreases expression
ISO
9
11,165,631
11,204,135
RGD:6480464
CTD
G
Cdc73
cell division cycle 73
decreases expression
ISO
13
57,441,674
57,534,385
RGD:6480464
CTD
G
Cdca7
cell division cycle associated 7
decreases expression
ISO
3
54,948,493
54,959,128
RGD:6480464
CTD
G
Cdh11
cadherin 11
increases expression
ISO
19
2,225,209
2,382,805
RGD:6480464
CTD
G
Cdk1
cyclin-dependent kinase 1
multiple interactions
ISO
20
20,018,044
20,044,030
RGD:6480464
CTD
G
Cdk1
cyclin-dependent kinase 1
decreases expression
ISO
20
20,018,044
20,044,030
RGD:6480464
CTD
G
Cdk1
cyclin-dependent kinase 1
multiple interactions
ISO
20
20,018,044
20,044,030
RGD:6480464
CTD
G
Cdk1
cyclin-dependent kinase 1
increases activity
ISO
20
20,018,044
20,044,030
RGD:6480464
CTD
G
Cdk1
cyclin-dependent kinase 1
multiple interactions
ISO
20
20,018,044
20,044,030
RGD:6480464
CTD
G
Cdk16
cyclin-dependent kinase 16
increases expression
EXP
X
12,910,972
12,916,939
RGD:6480464
CTD
G
Cdk2
cyclin dependent kinase 2
multiple interactions
ISO
7
2,000,196
2,007,682
RGD:6480464
CTD
G
Cdk2
cyclin dependent kinase 2
multiple interactions
ISO
7
2,000,196
2,007,682
RGD:6480464
CTD
G
Cdk2
cyclin dependent kinase 2
increases activity
ISO
7
2,000,196
2,007,682
RGD:6480464
CTD
G
Cdk2
cyclin dependent kinase 2
increases activity
ISO
7
2,000,196
2,007,682
RGD:6480464
CTD
G
Cdk20
cyclin-dependent kinase 20
decreases expression
ISO
17
6,221,255
6,227,959
RGD:6480464
CTD
G
Cdk7
cyclin-dependent kinase 7
multiple interactions
ISO
2
31,500,629
31,525,590
RGD:6480464
CTD
G
Cdk7
cyclin-dependent kinase 7
increases activity
ISO
2
31,500,629
31,525,590
RGD:6480464
CTD
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
multiple interactions
ISO
20
7,376,325
7,386,778
RGD:6480464
CTD
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
multiple interactions
ISO
20
7,376,325
7,386,778
RGD:6480464
CTD
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
ISO
20
7,376,325
7,386,778
RGD:6480464
CTD
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
ISO
20
7,376,325
7,386,778
RGD:6480464
CTD
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
multiple interactions
ISO
20
7,376,325
7,386,778
RGD:6480464
CTD
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
multiple interactions
ISO
20
7,376,325
7,386,778
RGD:6480464
CTD
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
ISO
20
7,376,325
7,386,778
RGD:6480464
CTD
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
ISO
20
7,376,325
7,386,778
RGD:6480464
CTD
G
Cdkn2c
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
affects response to substance
ISO
5
131,012,524
131,017,679
RGD:6480464
CTD
G
Cebpd
CCAAT/enhancer binding protein (C/EBP), delta
increases expression
EXP
RGD:6480464
CTD
G
Cenpf
centromere protein F
multiple interactions
ISO
13
105,920,242
105,965,655
RGD:6480464
CTD
G
Cenpf
centromere protein F
increases expression
ISO
13
105,920,242
105,965,655
RGD:6480464
CTD
G
Cfb
complement factor B
increases expression
EXP
20
4,072,124
4,077,802
RGD:6480464
CTD
G
Cfd
complement factor D (adipsin)
increases expression
EXP
7
11,325,538
11,327,261
RGD:6480464
CTD
G
Cflar
CASP8 and FADD-like apoptosis regulator
decreases response to substance
ISO
9
57,309,836
57,356,635
RGD:6480464
CTD
G
Chchd3
coiled-coil-helix-coiled-coil-helix domain containing 3
decreases expression
ISO
4
59,891,615
60,170,903
RGD:6480464
CTD
G
Chek1
checkpoint kinase 1
decreases expression
ISO
8
37,954,322
37,974,748
RGD:6480464
CTD
G
Chfr
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
affects response to substance
ISO
12
46,651,265
46,684,689
RGD:6480464
CTD
G
Chfr
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
decreases response to substance
ISO
12
46,651,265
46,684,689
RGD:6480464
CTD
G
Chi3l1
chitinase 3-like 1 (cartilage glycoprotein-39)
increases expression
EXP
13
47,139,658
47,147,591
RGD:6480464
CTD
G
Cideb
cell death-inducing DFFA-like effector b
decreases expression
ISO
15
33,916,472
33,920,872
RGD:6480464
CTD
G
Cldn3
claudin 3
decreases response to substance
ISO
RGD:6480464
CTD
G
Clec10a
C-type lectin domain family 10, member A
increases expression
EXP
10
56,998,778
57,002,953
RGD:6480464
CTD
G
Clec11a
C-type lectin domain family 11, member A
increases expression
ISO
1
94,785,179
94,788,320
RGD:6480464
CTD
G
Clec4a3
C-type lectin domain family 4, member A3
increases expression
EXP
4
159,464,410
159,474,023
RGD:6480464
CTD
G
Clpx
ClpX caseinolytic peptidase X homolog (E. coli)
increases expression
ISO
8
69,530,991
69,572,018
RGD:6480464
CTD
G
Clu
clusterin
decreases response to substance
ISO
15
45,365,779
45,405,314
RGD:6480464
CTD
G
Clu
clusterin
decreases response to substance
ISO
15
45,365,779
45,405,314
RGD:6480464
CTD
G
Cnr2
cannabinoid receptor 2 (macrophage)
multiple interactions
EXP
5
154,674,754
154,702,552
RGD:6480464
CTD
G
Cnr2
cannabinoid receptor 2 (macrophage)
multiple interactions
EXP
5
154,674,754
154,702,552
RGD:6480464
CTD
G
Coch
cochlin
increases expression
EXP
6
71,692,946
71,697,056
RGD:6480464
CTD
G
Col18a1
collagen, type XVIII, alpha 1
increases expression
ISO
20
11,920,816
11,982,468
RGD:6480464
CTD
G
Col1a1
collagen, type I, alpha 1
increases expression
ISO
10
83,622,438
83,639,368
RGD:6480464
CTD
G
Col1a2
collagen, type I, alpha 2
increases expression
ISO
4
29,393,645
29,428,572
RGD:6480464
CTD
G
Col4a1
collagen, type IV, alpha 1
increases expression
ISO
16
83,045,183
83,157,835
RGD:6480464
CTD
G
Col4a2
collagen, type IV, alpha 2
increases expression
ISO
16
82,899,206
83,045,102
RGD:6480464
CTD
G
Col6a1
collagen, type VI, alpha 1
increases expression
ISO
20
12,320,102
12,338,500
RGD:6480464
CTD
G
Col6a2
collagen, type VI, alpha 2
increases expression
ISO
20
12,436,783
12,464,512
RGD:6480464
CTD
G
Col6a3
collagen, type VI, alpha 3
affects response to substance
ISO
9
89,990,129
90,043,697
RGD:6480464
CTD
G
Col7a1
collagen, type VII, alpha 1
increases response to substance
ISO
8
113,971,207
114,003,445
RGD:6480464
CTD
G
Cope
coatomer protein complex, subunit epsilon
affects response to substance
ISO
16
19,602,842
19,609,515
RGD:6480464
CTD
G
Cox15
cytochrome c oxidase assembly homolog 15 (yeast)
decreases expression
ISO
1
247,077,102
247,093,757
RGD:6480464
CTD
G
Cox17
COX17 cytochrome c oxidase copper chaperone
affects response to substance
ISO
11
64,183,573
64,185,985
RGD:6480464
CTD
G
Cp
ceruloplasmin (ferroxidase)
increases expression
EXP
2
105,086,278
105,135,367
RGD:6480464
CTD
G
Creg1
cellular repressor of E1A-stimulated genes 1
affects response to substance
ISO
13
81,491,304
81,503,755
RGD:6480464
CTD
G
Csf3
colony stimulating factor 3 (granulocyte)
multiple interactions
ISO
10
87,473,990
87,476,365
RGD:6480464
CTD
G
Ctcf
CCCTC-binding factor (zinc finger protein)
decreases response to substance
ISO
19
35,461,942
35,514,934
RGD:6480464
CTD
G
Ctnnb1
catenin (cadherin associated protein), beta 1
decreases response to substance
ISO
8
125,978,161
125,987,670
RGD:6480464
CTD
G
Ctnnd2
catenin (cadherin-associated protein), delta 2
multiple interactions
ISO
2
82,238,091
83,088,901
RGD:6480464
CTD
G
Ctse
cathepsin E
increases expression
EXP
13
44,582,911
44,605,241
RGD:6480464
CTD
G
Ctsk
cathepsin K
increases expression
EXP
2
190,394,854
190,405,668
RGD:6480464
CTD
G
Ctsl1
cathepsin L1
increases response to substance
ISO
17
6,288,013
6,294,174
RGD:6480464
CTD
G
Ctss
cathepsin S
increases expression
EXP
2
190,425,290
190,466,877
RGD:6480464
CTD
G
Cttn
cortactin
decreases expression
ISO
1
204,865,768
204,901,221
RGD:6480464
CTD
G
Cxcl1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
increases expression
EXP
14
18,690,339
18,692,118
RGD:6480464
CTD
G
Cxcl10
chemokine (C-X-C motif) ligand 10
increases expression
ISO
14
17,265,986
17,268,183
RGD:6480464
CTD
G
Cxcl10
chemokine (C-X-C motif) ligand 10
multiple interactions
ISO
14
17,265,986
17,268,183
RGD:6480464
CTD
G
Cxcl14
chemokine (C-X-C motif) ligand 14
increases expression
EXP
17
14,286,747
14,295,502
RGD:6480464
CTD
G
Cxcl5
chemokine (C-X-C motif) ligand 5
affects response to substance
ISO
14
18,825,357
18,826,269
RGD:6480464
CTD
G
Cxcr4
chemokine (C-X-C motif) receptor 4
decreases response to substance
ISO
13
41,308,286
41,312,190
RGD:6480464
CTD
G
Cxcr6
chemokine (C-X-C motif) receptor 6
decreases response to substance
ISO
8
128,569,564
128,570,619
RGD:6480464
CTD
G
Cxcr7
chemokine (C-X-C motif) receptor 7
decreases response to substance
ISO
9
89,343,528
89,355,053
RGD:6480464
CTD
G
Cycs
cytochrome c, somatic
multiple interactions
ISO
4
78,825,878
78,827,978
RGD:6480464
CTD
G
Cycs
cytochrome c, somatic
increases expression
ISO
4
78,825,878
78,827,978
RGD:6480464
CTD
G
Cycs
cytochrome c, somatic
multiple interactions
ISO
4
78,825,878
78,827,978
RGD:6480464
CTD
G
Cycs
cytochrome c, somatic
increases secretion
ISO
4
78,825,878
78,827,978
RGD:6480464
CTD
G
Cycs
cytochrome c, somatic
affects localization
ISO
4
78,825,878
78,827,978
RGD:6480464
CTD
G
Cycs
cytochrome c, somatic
multiple interactions
ISO
4
78,825,878
78,827,978
RGD:6480464
CTD
G
Cycs
cytochrome c, somatic
multiple interactions
ISO
4
78,825,878
78,827,978
RGD:6480464
CTD
G
Cycs
cytochrome c, somatic
affects localization
ISO
4
78,825,878
78,827,978
RGD:6480464
CTD
G
Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1
increases activity
ISO
RGD:6480464
CTD
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
multiple interactions
ISO
8
61,462,207
61,468,237
RGD:6480464
CTD
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
increases expression
EXP
8
61,439,062
61,447,861
RGD:6480464
CTD
G
Cyp2c12
cytochrome P450, family 2, subfamily c, polypeptide 12
increases expression
EXP
RGD:6480464
CTD
G
Cyp2c79
cytochrome P450, family 2, subfamily c, polypeptide 79
multiple interactions
ISO
1
244,400,004
244,493,624
RGD:6480464
CTD
G
Cyp2c79
cytochrome P450, family 2, subfamily c, polypeptide 79
increases response to substance
ISO
1
244,400,004
244,493,624
RGD:6480464
CTD
G
Cyp2c79
cytochrome P450, family 2, subfamily c, polypeptide 79
affects metabolic processing
ISO
1
244,400,004
244,493,624
RGD:6480464
CTD
G
Cyp2c79
cytochrome P450, family 2, subfamily c, polypeptide 79
increases oxidation
ISO
1
244,400,004
244,493,624
RGD:6480464
CTD
G
Cyp2c79
cytochrome P450, family 2, subfamily c, polypeptide 79
increases metabolic processing
ISO
1
244,400,004
244,493,624
RGD:6480464
CTD
G
Cyp2c79
cytochrome P450, family 2, subfamily c, polypeptide 79
increases hydroxylation
ISO
1
244,400,004
244,493,624
RGD:6480464
CTD
G
Cyp2c79
cytochrome P450, family 2, subfamily c, polypeptide 79
increases metabolic processing
ISO
1
244,400,004
244,493,624
RGD:6480464
CTD
G
Cyp2c79
cytochrome P450, family 2, subfamily c, polypeptide 79
multiple interactions
ISO
1
244,400,004
244,493,624
RGD:6480464
CTD
G
Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
affects metabolic processing
ISO
12
9,517,016
9,541,000
RGD:6480464
CTD
G
Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
increases activity
ISO
12
9,517,016
9,541,000
RGD:6480464
CTD
G
Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
increases expression
ISO
12
9,517,016
9,541,000
RGD:6480464
CTD
G
Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
increases expression
EXP
12
9,517,016
9,541,000
RGD:6480464
CTD
G
Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
multiple interactions
EXP
12
9,517,016
9,541,000
RGD:6480464
CTD
G
Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
increases activity
ISO
12
9,517,016
9,541,000
RGD:6480464
CTD
G
Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
increases expression
ISO
12
9,517,016
9,541,000
RGD:6480464
CTD
G
Cyp4a8
cytochrome P450, family 4, subfamily a, polypeptide 8
increases expression
EXP
5
135,546,858
135,578,199
RGD:6480464
CTD
G
Cyp7a1
cytochrome P450, family 7, subfamily a, polypeptide 1
decreases expression
EXP
5
19,707,159
19,716,856
RGD:6480464
CTD
G
Cyr61
cysteine-rich, angiogenic inducer, 61
increases response to substance
ISO
2
243,824,303
243,827,262
RGD:6480464
CTD
G
Dbf4
DBF4 homolog (S. cerevisiae)
decreases expression
ISO
4
22,522,387
22,547,180
RGD:6480464
CTD
G
Dctd
dCMP deaminase
affects response to substance
ISO
16
47,240,976
47,261,942
RGD:6480464
CTD
G
Ddx23
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
affects response to substance
ISO
7
137,394,834
137,412,075
RGD:6480464
CTD
G
Dedd
death effector domain-containing
decreases expression
ISO
13
87,238,315
87,241,703
RGD:6480464
CTD
G
Dffa
DNA fragmentation factor, alpha subunit
multiple interactions
ISO
5
166,179,130
166,192,029
RGD:6480464
CTD
G
Dffa
DNA fragmentation factor, alpha subunit
decreases expression
ISO
5
166,179,130
166,192,029
RGD:6480464
CTD
G
Dffa
DNA fragmentation factor, alpha subunit
increases cleavage
ISO
5
166,179,130
166,192,029
RGD:6480464
CTD
G
Dhcr24
24-dehydrocholesterol reductase
affects response to substance
ISO
5
127,637,438
127,662,621
RGD:6480464
CTD
G
Diablo
diablo, IAP-binding mitochondrial protein
affects localization
ISO
12
34,196,347
34,209,633
RGD:6480464
CTD
G
Diablo
diablo, IAP-binding mitochondrial protein
increases expression
ISO
12
34,196,347
34,209,633
RGD:6480464
CTD
G
Diablo
diablo, IAP-binding mitochondrial protein
multiple interactions
ISO
12
34,196,347
34,209,633
RGD:6480464
CTD
G
Diablo
diablo, IAP-binding mitochondrial protein
multiple interactions
ISO
12
34,196,347
34,209,633
RGD:6480464
CTD
G
Diablo
diablo, IAP-binding mitochondrial protein
multiple interactions
ISO
12
34,196,347
34,209,633
RGD:6480464
CTD
G
Dmtf1
cyclin D binding myb-like transcription factor 1
decreases expression
ISO
4
21,329,397
21,369,691
RGD:6480464
CTD
G
Dnase1l3
deoxyribonuclease 1-like 3
decreases expression
EXP
15
18,909,363
18,935,347
RGD:6480464
CTD
G
Dpyd
dihydropyrimidine dehydrogenase
affects expression
ISO
2
214,931,901
215,818,809
RGD:6480464
CTD
G
Dpyd
dihydropyrimidine dehydrogenase
decreases expression
ISO
2
214,931,901
215,818,809
RGD:6480464
CTD
G
Dpyd
dihydropyrimidine dehydrogenase
multiple interactions
ISO
2
214,931,901
215,818,809
RGD:6480464
CTD
G
Dsp
desmoplakin
affects response to substance
ISO
17
32,848,313
32,896,044
RGD:6480464
CTD
G
Dusp3
dual specificity phosphatase 3
decreases expression
ISO
10
91,031,206
91,044,858
RGD:6480464
CTD
G
E2f1
E2F transcription factor 1
increases response to substance
ISO
3
145,032,489
145,043,729
RGD:6480464
CTD
G
E2f3
E2F transcription factor 3
multiple interactions
ISO
17
41,079,346
41,145,568
RGD:6480464
CTD
G
E2f5
E2F transcription factor 5
increases expression
ISO
2
88,346,236
88,361,733
RGD:6480464
CTD
G
Ech1
enoyl CoA hydratase 1, peroxisomal
increases expression
EXP
1
83,932,720
83,938,918
RGD:6480464
CTD
G
Eef2
eukaryotic translation elongation factor 2
decreases expression
ISO
7
10,017,061
10,022,331
RGD:6480464
CTD
G
Efcab7
EF-hand calcium binding domain 7
affects response to substance
ISO
5
120,525,527
120,576,068
RGD:6480464
CTD
G
Efna1
ephrin A1
decreases expression
ISO
2
181,444,599
181,451,944
RGD:6480464
CTD
G
Egf
epidermal growth factor
decreases expression
ISO
2
227,103,900
227,195,062
RGD:6480464
CTD
G
Egfr
epidermal growth factor receptor
multiple interactions
ISO
14
97,617,358
97,788,211
RGD:6480464
CTD
G
Egfr
epidermal growth factor receptor
increases phosphorylation
ISO
14
97,617,358
97,788,211
RGD:6480464
CTD
G
Egfr
epidermal growth factor receptor
decreases expression
ISO
14
97,617,358
97,788,211
RGD:6480464
CTD
G
Egfr
epidermal growth factor receptor
multiple interactions
ISO
14
97,617,358
97,788,211
RGD:6480464
CTD
G
Egfr
epidermal growth factor receptor
increases phosphorylation
ISO
14
97,617,358
97,788,211
RGD:6480464
CTD
G
Ehf
ets homologous factor
decreases expression
ISO
3
88,518,893
88,557,065
RGD:6480464
CTD
G
Eif2ak3
eukaryotic translation initiation factor 2 alpha kinase 3
affects response to substance
ISO
4
104,016,940
104,078,261
RGD:6480464
CTD
G
Eif4a1
eukaryotic translation initiation factor 4A1
decreases expression
ISO
10
56,484,232
56,489,739
RGD:6480464
CTD
G
Eif5a
eukaryotic translation initiation factor 5A
increases response to substance
ISO
10
56,760,289
56,764,689
RGD:6480464
CTD
G
Elk1
ELK1, member of ETS oncogene family
decreases expression
ISO
X
12,597,863
12,604,248
RGD:6480464
CTD
G
Elmo3
engulfment and cell motility 3
increases expression
ISO
19
35,119,813
35,124,187
RGD:6480464
CTD
G
Emp1
epithelial membrane protein 1
increases expression
EXP
4
172,315,122
172,335,536
RGD:6480464
CTD
G
Emp3
epithelial membrane protein 3
increases expression
ISO
1
96,389,783
96,392,960
RGD:6480464
CTD
G
Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
increases expression
ISO
7
91,295,824
91,377,850
RGD:6480464
CTD
G
Epcam
epithelial cell adhesion molecule
decreases expression
ISO
6
11,176,664
11,192,628
RGD:6480464
CTD
G
Epcam
epithelial cell adhesion molecule
decreases expression
ISO
6
11,176,664
11,192,628
RGD:6480464
CTD
G
Ephx2
epoxide hydrolase 2, cytoplasmic
increases expression
EXP
15
45,497,660
45,556,101
RGD:6480464
CTD
G
Epo
erythropoietin
decreases response to substance
ISO
12
19,551,768
19,555,208
RGD:6480464
CTD
G
Erbb2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
multiple interactions
ISO
10
87,219,157
87,242,919
RGD:6480464
CTD
G
Erbb2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
multiple interactions
ISO
10
87,219,157
87,242,919
RGD:6480464
CTD
G
Erbb2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
decreases response to substance
ISO
10
87,219,157
87,242,919
RGD:6480464
CTD
G
Erbb2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
affects response to substance
ISO
10
87,219,157
87,242,919
RGD:6480464
CTD
G
Erbb3
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
decreases response to substance
ISO
7
1,858,057
1,877,353
RGD:6480464
CTD
G
Erbb4
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
multiple interactions
ISO
9
66,843,898
67,967,970
RGD:6480464
CTD
G
Ercc5
excision repair cross-complementing rodent repair deficiency, complementation group 5
increases expression
ISO
9
43,248,023
43,293,196
RGD:6480464
CTD
G
Esr1
estrogen receptor 1
multiple interactions
ISO
1
35,523,680
35,759,891
RGD:6480464
CTD
G
Esr1
estrogen receptor 1
increases expression
ISO
1
35,523,680
35,759,891
RGD:6480464
CTD
G
Esr2
estrogen receptor 2 (ER beta)
multiple interactions
ISO
6
98,691,167
98,775,299
RGD:6480464
CTD
G
Esr2
estrogen receptor 2 (ER beta)
increases expression
ISO
6
98,691,167
98,775,299
RGD:6480464
CTD
G
F13a1
coagulation factor XIII, A1 polypeptide
increases expression
EXP
17
34,093,525
34,270,498
RGD:6480464
CTD
G
F2
coagulation factor II
multiple interactions
ISO
3
76,005,318
76,018,603
RGD:6480464
CTD
G
F3
coagulation factor III (thromboplastin, tissue factor)
multiple interactions
ISO
2
218,371,050
218,382,645
RGD:6480464
CTD
G
Fadd
Fas (TNFRSF6)-associated via death domain
multiple interactions
ISO
1
205,010,363
205,012,768
RGD:6480464
CTD
G
Fadd
Fas (TNFRSF6)-associated via death domain
increases expression
ISO
1
205,010,363
205,012,768
RGD:6480464
CTD
G
Fadd
Fas (TNFRSF6)-associated via death domain
increases phosphorylation
ISO
1
205,010,363
205,012,768
RGD:6480464
CTD
G
Fam3c
family with sequence similarity 3, member C
affects response to substance
ISO
4
48,628,905
48,676,252
RGD:6480464
CTD
G
Fancl
Fanconi anemia, complementation group L
affects response to substance
ISO
14
107,211,448
107,276,828
RGD:6480464
CTD
G
Fas
Fas cell surface death receptor
multiple interactions
ISO
1
238,259,443
238,274,745
RGD:6480464
CTD
G
Fas
Fas cell surface death receptor
multiple interactions
ISO
1
238,259,443
238,274,745
RGD:6480464
CTD
G
Fas
Fas cell surface death receptor
increases response to substance
ISO
1
238,259,443
238,274,745
RGD:6480464
CTD
G
Fas
Fas cell surface death receptor
decreases expression
ISO
1
238,259,443
238,274,745
RGD:6480464
CTD
G
Fas
Fas cell surface death receptor
increases expression
ISO
1
238,259,443
238,274,745
RGD:6480464
CTD
G
Fas
Fas cell surface death receptor
increases expression
ISO
1
238,259,443
238,274,745
RGD:6480464
CTD
G
Faslg
Fas ligand (TNF superfamily, member 6)
multiple interactions
ISO
13
77,472,950
77,480,210
RGD:6480464
CTD
G
Faslg
Fas ligand (TNF superfamily, member 6)
multiple interactions
ISO
13
77,472,950
77,480,210
RGD:6480464
CTD
G
Faslg
Fas ligand (TNF superfamily, member 6)
increases response to substance
ISO
13
77,472,950
77,480,210
RGD:6480464
CTD
G
Faslg
Fas ligand (TNF superfamily, member 6)
increases expression
ISO
13
77,472,950
77,480,210
RGD:6480464
CTD
G
Faslg
Fas ligand (TNF superfamily, member 6)
increases expression
ISO
13
77,472,950
77,480,210
RGD:6480464
CTD
G
Faslg
Fas ligand (TNF superfamily, member 6)
increases expression
ISO
13
77,472,950
77,480,210
RGD:6480464
CTD
G
Fbn1
fibrillin 1
increases expression
ISO
3
112,608,480
112,804,118
RGD:6480464
CTD
G
Fcgr2b
Fc fragment of IgG, low affinity IIb, receptor (CD32)
increases expression
EXP
13
86,809,011
86,823,599
RGD:6480464
CTD
G
Fdft1
farnesyl diphosphate farnesyl transferase 1
affects response to substance
ISO
15
42,425,336
42,453,390
RGD:6480464
CTD
G
Fdps
farnesyl diphosphate synthase
increases response to substance
ISO
2
181,138,474
181,177,903
RGD:6480464
CTD
G
Fgb
fibrinogen beta chain
decreases expression
EXP
2
174,768,193
174,775,102
RGD:6480464
CTD
G
Fgf2
fibroblast growth factor 2
decreases response to substance
ISO
2
123,893,314
123,947,136
RGD:6480464
CTD
G
Fgf5
fibroblast growth factor 5
affects response to substance
ISO
14
12,713,971
12,734,634
RGD:6480464
CTD
G
Fhl1
four and a half LIM domains 1
increases response to substance
ISO
X
141,315,765
141,329,278
RGD:6480464
CTD
G
Fkbp3
FK506 binding protein 3
increases expression
ISO
6
86,410,859
86,422,588
RGD:6480464
CTD
G
Flt1
FMS-related tyrosine kinase 1
increases expression
ISO
12
7,858,092
8,035,966
RGD:6480464
CTD
G
Fth1
ferritin, heavy polypeptide 1
decreases response to substance
ISO
1
212,430,453
212,432,741
RGD:6480464
CTD
G
Ftl
ferritin, light polypeptide
decreases response to substance
ISO
1
95,929,248
95,931,092
RGD:6480464
CTD
G
Furin
furin (paired basic amino acid cleaving enzyme)
decreases response to substance
ISO
1
136,209,969
136,222,057
RGD:6480464
CTD
G
Fxyd3
FXYD domain-containing ion transport regulator 3
decreases expression
ISO
1
86,113,706
86,120,488
RGD:6480464
CTD
G
Fxyd3
FXYD domain-containing ion transport regulator 3
increases response to substance
ISO
1
86,113,706
86,120,488
RGD:6480464
CTD
G
G0s2
G0/G1switch 2
increases expression
EXP
13
109,121,297
109,122,209
RGD:6480464
CTD
G
G6pc
glucose-6-phosphatase, catalytic subunit
increases expression
EXP
10
90,393,531
90,403,485
RGD:6480464
CTD
G
Gadd45a
growth arrest and DNA-damage-inducible, alpha
decreases response to substance
ISO
4
96,649,941
96,652,243
RGD:6480464
CTD
G
Gadd45a
growth arrest and DNA-damage-inducible, alpha
increases expression
ISO
4
96,649,941
96,652,243
RGD:6480464
CTD
G
Galnt7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
affects response to substance
ISO
16
35,996,633
36,119,925
RGD:6480464
CTD
G
Gamt
guanidinoacetate N-methyltransferase
multiple interactions
ISO
7
10,959,990
10,962,720
RGD:6480464
CTD
G
Gchfr
GTP cyclohydrolase I feedback regulator
decreases response to substance
ISO
3
105,683,288
105,687,349
RGD:6480464
CTD
G
Gckr
glucokinase (hexokinase 4) regulator
increases expression
EXP
RGD:6480464
CTD
G
Gfap
glial fibrillary acidic protein
increases expression
ISO
10
92,059,881
92,068,555
RGD:6480464
CTD
G
Gfap
glial fibrillary acidic protein
increases expression
EXP
10
92,059,881
92,068,555
RGD:6480464
CTD
G
Gfap
glial fibrillary acidic protein
multiple interactions
ISO
10
92,059,881
92,068,555
RGD:6480464
CTD
G
Gfap
glial fibrillary acidic protein
increases expression
EXP
10
92,059,881
92,068,555
RGD:6480464
CTD
G
Gfpt1
glutamine fructose-6-phosphate transaminase 1
decreases response to substance
ISO
4
121,204,274
121,250,160
RGD:6480464
CTD
G
Gfra1
GDNF family receptor alpha 1
multiple interactions
ISO
1
264,614,329
264,875,486
RGD:6480464
CTD
G
Gjb2
gap junction protein, beta 2
increases expression
EXP
15
36,153,526
36,159,490
RGD:6480464
CTD
G
Gjb6
gap junction protein, beta 6
increases expression
EXP
15
36,177,736
36,186,513
RGD:6480464
CTD
G
Gpi
glucose-6-phosphate isomerase
affects response to substance
ISO
1
86,658,836
86,686,712
RGD:6480464
CTD
G
Gpnmb
glycoprotein (transmembrane) nmb
increases expression
EXP
4
77,161,352
77,182,624
RGD:6480464
CTD
G
Gpr35
G protein-coupled receptor 35
decreases response to substance
ISO
9
92,258,279
92,259,199
RGD:6480464
CTD
G
Gsn
gelsolin
decreases expression
ISO
3
14,360,245
14,386,313
RGD:6480464
CTD
G
Gstm1
glutathione S-transferase mu 1
multiple interactions
ISO
2
203,575,444
203,580,821
RGD:6480464
CTD
G
Gstp1
glutathione S-transferase pi 1
increases response to substance
ISO
1
206,627,398
206,629,866
RGD:6480464
CTD
G
Gstp1
glutathione S-transferase pi 1
affects response to substance
ISO
1
206,627,398
206,629,866
RGD:6480464
CTD
G
Gstt1
glutathione S-transferase theta 1
multiple interactions
ISO
20
13,604,355
13,621,456
RGD:6480464
CTD
G
Gtf2a2
general transcription factor IIA, 2
increases expression
EXP
8
74,447,866
74,456,735
RGD:6480464
CTD
G
Gtf2i
general transcription factor II I
decreases expression
ISO
12
23,470,042
23,545,621
RGD:6480464
CTD
G
Gtse1
G-2 and S-phase expressed 1
increases expression
ISO
7
123,862,066
123,878,554
RGD:6480464
CTD
G
Gusb
glucuronidase, beta
affects response to substance
ISO
12
27,744,409
27,757,755
RGD:6480464
CTD
G
H2afx
H2A histone family, member X
increases expression
ISO
8
47,312,609
47,313,938
RGD:6480464
CTD
G
Hacl1
2-hydroxyacyl-CoA lyase 1
increases expression
EXP
16
7,073,038
7,108,830
RGD:6480464
CTD
G
Hdac9
histone deacetylase 9
increases response to substance
ISO
6
53,066,308
53,114,402
RGD:6480464
CTD
G
Hmbs
hydroxymethylbilane synthase
decreases expression
EXP
8
47,314,235
47,321,604
RGD:6480464
CTD
G
Hmgb1
high mobility group box 1
affects response to substance
ISO
RGD:6480464
CTD
G
Hmgcs2
3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
increases expression
EXP
2
193,128,736
193,143,106
RGD:6480464
CTD
G
Hmgn3
high mobility group nucleosome binding domain 3
affects response to substance
ISO
8
88,168,415
88,205,046
RGD:6480464
CTD
G
Hmmr
hyaluronan mediated motility receptor (RHAMM)
decreases expression
ISO
10
25,733,375
25,762,825
RGD:6480464
CTD
G
Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
decreases expression
ISO
4
79,700,327
79,704,116
RGD:6480464
CTD
G
Hnrnpab
heterogeneous nuclear ribonucleoprotein A/B
decreases expression
ISO
10
37,117,285
37,123,177
RGD:6480464
CTD
G
Hnrph1
heterogeneous nuclear ribonucleoprotein H1
decreases expression
ISO
10
35,922,840
35,930,132
RGD:6480464
CTD
G
Hook1
hook homolog 1 (Drosophila)
decreases expression
ISO
5
116,324,845
116,397,148
RGD:6480464
CTD
G
Hsd17b4
hydroxysteroid (17-beta) dehydrogenase 4
affects response to substance
ISO
18
45,157,435
45,251,606
RGD:6480464
CTD
G
Hspa1l
heat shock protein 1-like
increases expression
EXP
RGD:6480464
CTD
G
Hspb3
heat shock protein 3
increases expression
ISO
2
45,078,615
45,079,329
RGD:6480464
CTD
G
Icam1
intercellular adhesion molecule 1
multiple interactions
ISO
8
20,040,177
20,051,939
RGD:6480464
CTD
G
Icam1
intercellular adhesion molecule 1
decreases expression
ISO
8
20,040,177
20,051,939
RGD:6480464
CTD
G
Idh2
isocitrate dehydrogenase 2 (NADP+), mitochondrial
affects response to substance
ISO
1
135,876,052
135,895,373
RGD:6480464
CTD
G
Idh2
isocitrate dehydrogenase 2 (NADP+), mitochondrial
decreases expression
ISO
1
135,876,052
135,895,373
RGD:6480464
CTD
G
Ier3
immediate early response 3
increases expression
ISO
20
3,076,568
3,077,772
RGD:6480464
CTD
G
Ifi30
interferon gamma inducible protein 30
decreases response to substance
ISO
16
19,181,236
19,185,438
RGD:6480464
CTD
G
Igfbp4
insulin-like growth factor binding protein 4
multiple interactions
ISO
10
87,822,429
87,834,315
RGD:6480464
CTD
G
Igfbp4
insulin-like growth factor binding protein 4
increases expression
ISO
10
87,822,429
87,834,315
RGD:6480464
CTD
G
Igfbp6
insulin-like growth factor binding protein 6
increases expression
EXP
7
140,885,388
140,890,028
RGD:6480464
CTD
G
Ikbkb
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
affects response to substance
ISO
16
73,804,730
73,858,510
RGD:6480464
CTD
G
Il10
interleukin 10
increases expression
ISO
13
43,953,900
43,957,766
RGD:6480464
CTD
G
Il12a
interleukin 12A
multiple interactions
ISO
2
158,710,261
158,717,689
RGD:6480464
CTD
G
Il12a
interleukin 12A
increases expression
ISO
2
158,710,261
158,717,689
RGD:6480464
CTD
G
Il12b
interleukin 12B
multiple interactions
ISO
10
29,558,955
29,568,331
RGD:6480464
CTD
G
Il12b
interleukin 12B
increases expression
ISO
10
29,558,955
29,568,331
RGD:6480464
CTD
G
Il13ra2
interleukin 13 receptor, alpha 2
affects response to substance
ISO
X
30,505,850
30,533,002
RGD:6480464
CTD
G
Il17rb
interleukin 17 receptor B
decreases response to substance
ISO
16
5,335,806
5,349,160
RGD:6480464
CTD
G
Il1b
interleukin 1 beta
increases expression
EXP
3
116,964,422
116,970,867
RGD:6480464
CTD
G
Il1r1
interleukin 1 receptor, type I
decreases expression
ISO
9
39,434,910
39,473,552
RGD:6480464
CTD
G
Il6
interleukin 6
increases expression
ISO
4
456,799
461,376
RGD:6480464
CTD
G
Il6
interleukin 6
affects response to substance
ISO
4
456,799
461,376
RGD:6480464
CTD
G
Insig1
insulin induced gene 1
affects response to substance
ISO
4
2,577,468
2,585,682
RGD:6480464
CTD
G
Ip6k1
inositol hexakisphosphate kinase 1
decreases expression
EXP
8
113,294,932
113,314,025
RGD:6480464
CTD
G
Irf7
interferon regulatory factor 7
increases expression
EXP
1
201,456,689
201,459,756
RGD:6480464
CTD
G
Irf8
interferon regulatory factor 8
increases expression
ISO
19
51,100,088
51,116,730
RGD:6480464
CTD
G
Irf8
interferon regulatory factor 8
multiple interactions
ISO
19
51,100,088
51,116,730
RGD:6480464
CTD
G
Isg15
ISG15 ubiquitin-like modifier
affects response to substance
ISO
5
173,034,479
173,035,766
RGD:6480464
CTD
G
Itga2
integrin, alpha 2
increases response to substance
EXP
2
46,967,681
47,080,909
RGD:6480464
CTD
G
Itgam
integrin, alpha M
multiple interactions
ISO
1
187,334,413
187,385,583
RGD:6480464
CTD
G
Itgam
integrin, alpha M
increases expression
EXP
1
187,334,413
187,385,583
RGD:6480464
CTD
G
Itgb1
integrin, beta 1
increases response to substance
EXP
19
58,600,095
58,647,531
RGD:6480464
CTD
G
Itgb1bp1
integrin beta 1 binding protein 1
affects response to substance
ISO
6
41,830,110
41,844,514
RGD:6480464
CTD
G
Itgb5
integrin, beta 5
decreases response to substance
ISO
RGD:6480464
CTD
G
Itgb6
integrin, beta 6
decreases expression
ISO
3
42,286,140
42,360,793
RGD:6480464
CTD
G
Itm2b
integral membrane protein 2B
affects response to substance
ISO
15
54,005,134
54,028,036
RGD:6480464
CTD
G
Jun
jun proto-oncogene
increases phosphorylation
ISO
5
115,358,166
115,361,259
RGD:6480464
CTD
G
Jun
jun proto-oncogene
increases expression
EXP
5
115,358,166
115,361,259
RGD:6480464
CTD
G
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
increases expression
EXP
10
100,514,180
100,515,949
RGD:6480464
CTD
G
Kcnk3
potassium channel, subfamily K, member 3
increases expression
ISO
6
25,745,923
25,782,144
RGD:6480464
CTD
G
Kcnma1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
affects response to substance
ISO
15
575,136
950,275
RGD:6480464
CTD
G
Kdm4b
lysine (K)-specific demethylase 4B
multiple interactions
ISO
RGD:6480464
CTD
G
Kif3a
kinesin family member 3a
multiple interactions
ISO
10
39,029,351
39,062,570
RGD:6480464
CTD
G
Krt13
keratin 13
decreases response to substance
ISO
10
89,057,240
89,061,150
RGD:6480464
CTD
G
Krt19
keratin 19
increases expression
EXP
10
89,080,953
89,085,670
RGD:6480464
CTD
G
Krt7
keratin 7
increases response to substance
ISO
7
140,160,829
140,226,474
RGD:6480464
CTD
G
Lamp2
lysosomal-associated membrane protein 2
affects response to substance
ISO
X
6,908,285
6,951,772
RGD:6480464
CTD
G
Lbp
lipopolysaccharide binding protein
increases expression
EXP
3
149,016,605
149,043,530
RGD:6480464
CTD
G
Lcp2
lymphocyte cytosolic protein 2
increases expression
ISO
10
19,019,978
19,066,744
RGD:6480464
CTD
G
Ldha
lactate dehydrogenase A
increases expression
EXP
1
97,403,077
97,412,547
RGD:6480464
CTD
G
Ldlr
low density lipoprotein receptor
affects response to substance
ISO
8
20,824,040
20,846,920
RGD:6480464
CTD
G
Lgals4
lectin, galactoside-binding, soluble, 4
decreases response to substance
ISO
1
83,942,899
83,950,613
RGD:6480464
CTD
G
Lig1
ligase I, DNA, ATP-dependent
decreases expression
ISO
1
73,728,892
73,767,429
RGD:6480464
CTD
G
Litaf
lipopolysaccharide-induced TNF factor
affects response to substance
ISO
10
4,614,177
4,623,903
RGD:6480464
CTD
G
LOC100360940
diablo-like
affects localization
ISO
5
148,562,065
148,563,619
RGD:6480464
CTD
G
LOC100360940
diablo-like
increases expression
ISO
5
148,562,065
148,563,619
RGD:6480464
CTD
G
LOC100360940
diablo-like
multiple interactions
ISO
5
148,562,065
148,563,619
RGD:6480464
CTD
G
LOC100360940
diablo-like
multiple interactions
ISO
5
148,562,065
148,563,619
RGD:6480464
CTD
G
LOC100360940
diablo-like
multiple interactions
ISO
5
148,562,065
148,563,619
RGD:6480464
CTD
G
Ltbp2
latent transforming growth factor beta binding protein 2
affects response to substance
ISO
6
108,826,446
108,924,746
RGD:6480464
CTD
G
Ly6c
Ly6-C antigen
increases expression
EXP
7
113,179,070
113,182,136
RGD:6480464
CTD
G
Mad2l1
MAD2 mitotic arrest deficient-like 1 (yeast)
affects response to substance
ISO
4
96,380,039
96,386,042
RGD:6480464
CTD
G
Mad2l1
MAD2 mitotic arrest deficient-like 1 (yeast)
decreases expression
ISO
4
96,380,039
96,386,042
RGD:6480464
CTD
G
Madd
MAP-kinase activating death domain
decreases expression
ISO
3
75,498,321
75,541,073
RGD:6480464
CTD
G
Map1lc3b
microtubule-associated protein 1 light chain 3 beta
increases expression
ISO
19
51,847,187
51,854,858
RGD:6480464
CTD
G
Map2k1
mitogen activated protein kinase kinase 1
multiple interactions
ISO
8
68,379,074
68,451,554
RGD:6480464
CTD
G
Map2k4
mitogen activated protein kinase kinase 4
multiple interactions
ISO
10
52,009,149
52,041,599
RGD:6480464
CTD
G
Map3k1
mitogen activated protein kinase kinase kinase 1
multiple interactions
ISO
2
43,062,252
43,126,058
RGD:6480464
CTD
G
Map3k1
mitogen activated protein kinase kinase kinase 1
affects localization
ISO
2
43,062,252
43,126,058
RGD:6480464
CTD
G
Map3k1
mitogen activated protein kinase kinase kinase 1
increases cleavage
ISO
2
43,062,252
43,126,058
RGD:6480464
CTD
G
Map3k5
mitogen-activated protein kinase kinase kinase 5
multiple interactions
ISO
1
15,205,361
15,346,422
RGD:6480464
CTD
G
Mapk1
mitogen activated protein kinase 1
multiple interactions
ISO
11
85,968,732
86,030,387
RGD:6480464
CTD
G
Mapk1
mitogen activated protein kinase 1
multiple interactions
ISO
11
85,968,732
86,030,387
RGD:6480464
CTD
G
Mapk1
mitogen activated protein kinase 1
multiple interactions
ISO
11
85,968,732
86,030,387
RGD:6480464
CTD
G
Mapk1
mitogen activated protein kinase 1
multiple interactions
ISO
11
85,968,732
86,030,387
RGD:6480464
CTD
G
Mapk1
mitogen activated protein kinase 1
decreases activity
ISO
11
85,968,732
86,030,387
RGD:6480464
CTD
G
Mapk1
mitogen activated protein kinase 1
increases activity
ISO
11
85,968,732
86,030,387
RGD:6480464
CTD
G
Mapk1
mitogen activated protein kinase 1
multiple interactions
ISO
11
85,968,732
86,030,387
RGD:6480464
CTD
G
Mapk1
mitogen activated protein kinase 1
multiple interactions
ISO
11
85,968,732
86,030,387
RGD:6480464
CTD
G
Mapk1
mitogen activated protein kinase 1
multiple interactions
ISO
11
85,968,732
86,030,387
RGD:6480464
CTD
G
Mapk1
mitogen activated protein kinase 1
multiple interactions
ISO
11
85,968,732
86,030,387
RGD:6480464
CTD
G
Mapk1
mitogen activated protein kinase 1
increases phosphorylation
ISO
11
85,968,732
86,030,387
RGD:6480464
CTD
G
Mapk1
mitogen activated protein kinase 1
multiple interactions
ISO
11
85,968,732
86,030,387
RGD:6480464
CTD
G
Mapk13
mitogen activated protein kinase 13
increases expression
ISO
20
7,055,313
7,064,405
RGD:6480464
CTD
G
Mapk14
mitogen activated protein kinase 14
multiple interactions
ISO
20
6,939,249
7,000,378
RGD:6480464
CTD
G
Mapk3
mitogen activated protein kinase 3
multiple interactions
ISO
1
185,935,044
185,941,245
RGD:6480464
CTD
G
Mapk3
mitogen activated protein kinase 3
increases phosphorylation
ISO
1
185,935,044
185,941,245
RGD:6480464
CTD
G
Mapk3
mitogen activated protein kinase 3
multiple interactions
ISO
1
185,935,044
185,941,245
RGD:6480464
CTD
G
Mapk3
mitogen activated protein kinase 3
multiple interactions
ISO
1
185,935,044
185,941,245
RGD:6480464
CTD
G
Mapk3
mitogen activated protein kinase 3
multiple interactions
ISO
1
185,935,044
185,941,245
RGD:6480464
CTD
G
Mapk3
mitogen activated protein kinase 3
increases activity
ISO
1
185,935,044
185,941,245
RGD:6480464
CTD
G
Mapk3
mitogen activated protein kinase 3
multiple interactions
ISO
1
185,935,044
185,941,245
RGD:6480464
CTD
G
Mapk3
mitogen activated protein kinase 3
multiple interactions
ISO
1
185,935,044
185,941,245
RGD:6480464
CTD
G
Mapk3
mitogen activated protein kinase 3
increases phosphorylation
ISO
1
185,935,044
185,941,245
RGD:6480464
CTD
G
Mapk3
mitogen activated protein kinase 3
multiple interactions
ISO
1
185,935,044
185,941,245
RGD:6480464
CTD
G
Mapk3
mitogen activated protein kinase 3
multiple interactions
ISO
1
185,935,044
185,941,245
RGD:6480464
CTD
G
Mapk3
mitogen activated protein kinase 3
multiple interactions
ISO
1
185,935,044
185,941,245
RGD:6480464
CTD
G
Mapk3
mitogen activated protein kinase 3
increases activity
ISO
1
185,935,044
185,941,245
RGD:6480464
CTD
G
Mapk3
mitogen activated protein kinase 3
multiple interactions
ISO
1
185,935,044
185,941,245
RGD:6480464
CTD
G
Mapk8
mitogen-activated protein kinase 8
multiple interactions
ISO
16
8,925,133
9,004,897
RGD:6480464
CTD
G
Mapk8
mitogen-activated protein kinase 8
multiple interactions
ISO
16
8,925,133
9,004,897
RGD:6480464
CTD
G
Mapk8
mitogen-activated protein kinase 8
multiple interactions
ISO
16
8,925,133
9,004,897
RGD:6480464
CTD
G
Mapk8
mitogen-activated protein kinase 8
multiple interactions
ISO
16
8,925,133
9,004,897
RGD:6480464
CTD
G
Mapk8
mitogen-activated protein kinase 8
multiple interactions
ISO
16
8,925,133
9,004,897
RGD:6480464
CTD
G
Mapk8
mitogen-activated protein kinase 8
increases expression
ISO
16
8,925,133
9,004,897
RGD:6480464
CTD
G
Mapk8
mitogen-activated protein kinase 8
increases activity
ISO
16
8,925,133
9,004,897
RGD:6480464
CTD
G
Mapk8
mitogen-activated protein kinase 8
increases phosphorylation
ISO
16
8,925,133
9,004,897
RGD:6480464
CTD
G
Mapk9
mitogen-activated protein kinase 9
multiple interactions
ISO
10
35,353,486
35,384,319
RGD:6480464
CTD
G
Mapk9
mitogen-activated protein kinase 9
multiple interactions
ISO
10
35,353,486
35,384,319
RGD:6480464
CTD
G
Mapk9
mitogen-activated protein kinase 9
increases expression
ISO
10
35,353,486
35,384,319
RGD:6480464
CTD
G
Mapk9
mitogen-activated protein kinase 9
increases expression
EXP
10
35,353,486
35,384,319
RGD:6480464
CTD
G
Mapkapk5
mitogen-activated protein kinase-activated protein kinase 5
affects response to substance
ISO
12
36,128,538
36,147,493
RGD:6480464
CTD
G
Mapre1
microtubule-associated protein, RP/EB family, member 1
multiple interactions
ISO
3
144,120,532
144,148,856
RGD:6480464
CTD
G
Mapre1
microtubule-associated protein, RP/EB family, member 1
decreases localization
ISO
3
144,120,532
144,148,856
RGD:6480464
CTD
G
Mapre3
microtubule-associated protein, RP/EB family, member 3
multiple interactions
ISO
6
25,496,282
25,506,449
RGD:6480464
CTD
G
Mapre3
microtubule-associated protein, RP/EB family, member 3
affects localization
ISO
6
25,496,282
25,506,449
RGD:6480464
CTD
G
Mapt
microtubule-associated protein tau
multiple interactions
ISO
10
93,411,098
93,508,762
RGD:6480464
CTD
G
Mapt
microtubule-associated protein tau
decreases expression
ISO
10
93,411,098
93,508,762
RGD:6480464
CTD
G
Mcl1
myeloid cell leukemia sequence 1
decreases expression
ISO
RGD:6480464
CTD
G
Mcpt1
mast cell protease 1
increases expression
EXP
15
34,270,481
34,273,035
RGD:6480464
CTD
G
Mdm2
p53 E3 ubiquitin protein ligase
decreases response to substance
ISO
7
56,996,694
57,020,926
RGD:6480464
CTD
G
Med1
mediator complex subunit 1
multiple interactions
ISO
10
86,917,525
86,959,080
RGD:6480464
CTD
G
Med13l
mediator complex subunit 13-like
multiple interactions
ISO
12
39,136,265
39,181,221
RGD:6480464
CTD
G
Med4
mediator complex subunit 4
affects response to substance
ISO
15
54,158,386
54,168,660
RGD:6480464
CTD
G
Melk
maternal embryonic leucine zipper kinase
multiple interactions
ISO
5
60,787,123
60,848,620
RGD:6480464
CTD
G
Men1
multiple endocrine neoplasia I
increases expression
EXP
1
209,114,987
209,120,837
RGD:6480464
CTD
G
Metrn
meteorin, glial cell differentiation regulator
multiple interactions
ISO
10
15,062,082
15,064,100
RGD:6480464
CTD
G
Mgmt
O-6-methylguanine-DNA methyltransferase
increases expression
ISO
1
196,629,366
196,866,937
RGD:6480464
CTD
G
Micb
MHC class I polypeptide-related sequence B
increases response to substance
ISO
1
78,199,668
78,216,687
RGD:6480464
CTD
G
Mlec
malectin
affects response to substance
ISO
12
42,729,870
42,740,346
RGD:6480464
CTD
G
Mmp1
matrix metallopeptidase 1 (interstitial collagenase)
affects response to substance
ISO
8
4,333,773
4,354,284
RGD:6480464
CTD
G
Mmp16
matrix metallopeptidase 16
decreases expression
ISO
5
32,352,311
32,586,469
RGD:6480464
CTD
G
Mmp17
matrix metallopeptidase 17
decreases expression
ISO
12
28,142,947
28,168,483
RGD:6480464
CTD
G
Mmp3
matrix metallopeptidase 3
increases expression
EXP
8
4,315,601
4,329,146
RGD:6480464
CTD
G
Mmp9
matrix metallopeptidase 9
multiple interactions
ISO
3
155,985,473
155,993,433
RGD:6480464
CTD
G
Mok
MOK protein kinase
affects response to substance
ISO
6
135,531,656
135,562,497
RGD:6480464
CTD
G
Mphosph6-ps1
M phase phosphoprotein 6, pseudogene
decreases expression
ISO
6
103,512,896
103,513,378
RGD:6480464
CTD
G
Mpp3
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
increases expression
ISO
10
91,057,154
91,085,728
RGD:6480464
CTD
G
Mpzl2
myelin protein zero-like 2
increases expression
EXP
8
47,991,599
48,003,100
RGD:6480464
CTD
G
Mpzl2
myelin protein zero-like 2
decreases expression
ISO
8
47,991,599
48,003,100
RGD:6480464
CTD
G
Mrc1
mannose receptor, C type 1
increases expression
EXP
17
88,411,265
88,492,622
RGD:6480464
CTD
G
Mrp63
mitochondrial ribosomal protein 63
affects response to substance
ISO
15
36,866,920
36,867,782
RGD:6480464
CTD
G
Mrpl40
mitochondrial ribosomal protein L40
affects response to substance
ISO
RGD:6480464
CTD
G
Mrps15
mitochondrial ribosomal protein S15
affects response to substance
ISO
5
145,397,772
145,408,365
RGD:6480464
CTD
G
Mrps18b
mitochondrial ribosomal protein S18B
decreases expression
ISO
20
2,985,972
2,992,031
RGD:6480464
CTD
G
Msmo1
methylsterol monooxygenase 1
affects response to substance
ISO
16
26,698,324
26,716,247
RGD:6480464
CTD
G
Mt2A
metallothionein 2A
increases response to substance
ISO
19
11,267,811
11,268,585
RGD:6480464
CTD
G
Muc16
mucin 16, cell surface associated
multiple interactions
ISO
8
16,552,167
16,726,561
RGD:6480464
CTD
G
Muc16
mucin 16, cell surface associated
decreases expression
ISO
8
16,552,167
16,726,561
RGD:6480464
CTD
G
Myc
myelocytomatosis oncogene
multiple interactions
ISO
7
98,953,142
98,958,060
RGD:6480464
CTD
G
Myc
myelocytomatosis oncogene
decreases expression
ISO
7
98,953,142
98,958,060
RGD:6480464
CTD
G
Myc
myelocytomatosis oncogene
affects response to substance
ISO
7
98,953,142
98,958,060
RGD:6480464
CTD
G
Myo5a
myosin VA
increases response to substance
ISO
8
79,909,224
80,027,290
RGD:6480464
CTD
G
Nampt
nicotinamide phosphoribosyltransferase
decreases expression
ISO
6
51,129,160
51,166,514
RGD:6480464
CTD
G
Nat1
N-acetyltransferase 1 (arylamine N-acetyltransferase)
decreases activity
ISO
16
23,845,894
23,876,528
RGD:6480464
CTD
G
Nat1
N-acetyltransferase 1 (arylamine N-acetyltransferase)
decreases expression
ISO
16
23,845,894
23,876,528
RGD:6480464
CTD
G
Nav3
neuron navigator 3
affects response to substance
ISO
7
48,505,502
48,862,109
RGD:6480464
CTD
G
Ncapg
non-SMC condensin I complex, subunit G
affects response to substance
ISO
14
70,465,952
70,494,296
RGD:6480464
CTD
G
Ncoa3
nuclear receptor coactivator 3
multiple interactions
ISO
3
157,168,492
157,196,566
RGD:6480464
CTD
G
Ndufa1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
affects response to substance
ISO
X
7,726,163
7,730,110
RGD:6480464
CTD
G
Ndufa13
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
affects response to substance
ISO
7
32,937,677
32,938,111
RGD:6480464
CTD
G
Ndufa3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3
affects response to substance
ISO
1
63,910,487
63,913,120
RGD:6480464
CTD
G
Ndufb2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
affects response to substance
ISO
4
67,099,841
67,106,920
RGD:6480464
CTD
G
Ndufb7
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7
affects response to substance
ISO
19
26,259,362
26,263,700
RGD:6480464
CTD
G
Ndufs8
NADH dehydrogenase (ubiquinone) Fe-S protein 8
affects response to substance
ISO
1
206,433,596
206,437,478
RGD:6480464
CTD
G
Ndufv1
NADH dehydrogenase (ubiquinone) flavoprotein 1
decreases expression
ISO
1
206,590,023
206,595,056
RGD:6480464
CTD
G
Neurod4
neuronal differentiation 4
decreases expression
ISO
7
8,534,957
8,547,130
RGD:6480464
CTD
G
Nfe2l2
nuclear factor, erythroid derived 2, like 2
decreases expression
EXP
3
58,366,693
58,394,116
RGD:6480464
CTD
G
Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
multiple interactions
ISO
2
233,091,013
233,187,501
RGD:6480464
CTD
G
Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
multiple interactions
ISO
2
233,091,013
233,187,501
RGD:6480464
CTD
G
Nfkbia
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
multiple interactions
ISO
6
75,729,302
75,732,475
RGD:6480464
CTD
G
Ngf
nerve growth factor (beta polypeptide)
decreases response to substance
EXP
2
197,621,726
197,632,960
RGD:6480464
CTD
G
Ngf
nerve growth factor (beta polypeptide)
decreases expression
EXP
2
197,621,726
197,632,960
RGD:6480464
CTD
G
Ngf
nerve growth factor (beta polypeptide)
multiple interactions
EXP
2
197,621,726
197,632,960
RGD:6480464
CTD
G
Nkain1
Na+/K+ transporting ATPase interacting 1
multiple interactions
ISO
5
149,695,153
149,734,122
RGD:6480464
CTD
G
Nme1
NME/NM23 nucleoside diphosphate kinase 1
increases expression
EXP
10
82,591,705
82,601,075
RGD:6480464
CTD
G
Nme4
NME/NM23 nucleoside diphosphate kinase 4
decreases expression
ISO
10
15,360,310
15,364,165
RGD:6480464
CTD
G
Nos3
nitric oxide synthase 3, endothelial cell
multiple interactions
ISO
4
6,158,847
6,179,441
RGD:6480464
CTD
G
Nos3
nitric oxide synthase 3, endothelial cell
decreases expression
ISO
4
6,158,847
6,179,441
RGD:6480464
CTD
G
Nos3
nitric oxide synthase 3, endothelial cell
decreases expression
ISO
4
6,158,847
6,179,441
RGD:6480464
CTD
G
Npy
neuropeptide Y
increases expression
EXP
4
78,038,013
78,045,187
RGD:6480464
CTD
G
Nr1i2
nuclear receptor subfamily 1, group I, member 2
multiple interactions
ISO
11
64,239,918
64,276,702
RGD:6480464
CTD
G
Nr1i2
nuclear receptor subfamily 1, group I, member 2
multiple interactions
ISO
11
64,239,918
64,276,702
RGD:6480464
CTD
G
Nr1i2
nuclear receptor subfamily 1, group I, member 2
multiple interactions
ISO
11
64,239,918
64,276,702
RGD:6480464
CTD
G
Nr1i2
nuclear receptor subfamily 1, group I, member 2
increases activity
ISO
11
64,239,918
64,276,702
RGD:6480464
CTD
G
Nr1i2
nuclear receptor subfamily 1, group I, member 2
multiple interactions
ISO
11
64,239,918
64,276,702
RGD:6480464
CTD
G
Nr1i2
nuclear receptor subfamily 1, group I, member 2
increases activity
ISO
11
64,239,918
64,276,702
RGD:6480464
CTD
G
Nrp1
neuropilin 1
increases expression
ISO
19
58,332,004
58,487,686
RGD:6480464
CTD
G
Nudt12
nudix (nucleoside diphosphate linked moiety X)-type motif 12
increases expression
ISO
9
97,551,943
97,565,919
RGD:6480464
CTD
G
Nudt15
nudix (nucleoside diphosphate linked moiety X)-type motif 15
affects response to substance
ISO
15
54,171,542
54,209,265
RGD:6480464
CTD
G
Nudt4
nudix (nucleoside diphosphate linked moiety X)-type motif 4
affects response to substance
ISO
7
32,753,728
32,769,953
RGD:6480464
CTD
G
Nupr1
nuclear protein, transcriptional regulator, 1
increases expression
EXP
1
185,770,310
185,772,313
RGD:6480464
CTD
G
Nus1
nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
decreases expression
ISO
20
31,143,886
31,170,668
RGD:6480464
CTD
G
Nusap1
nucleolar and spindle associated protein 1
affects response to substance
ISO
3
106,134,200
106,165,155
RGD:6480464
CTD
G
Oat
ornithine aminotransferase
increases expression
EXP
1
192,026,623
192,046,404
RGD:6480464
CTD
G
Obp3
alpha-2u globulin PGCL4
increases expression
EXP
5
78,088,876
78,092,317
RGD:6480464
CTD
G
Ogg1
8-oxoguanine DNA glycosylase
increases expression
ISO
4
149,209,745
149,219,081
RGD:6480464
CTD
G
Olfml3
olfactomedin-like 3
increases expression
ISO
2
198,958,480
198,961,309
RGD:6480464
CTD
G
Osbpl10
oxysterol binding protein-like 10
affects response to substance
ISO
8
119,386,782
119,670,147
RGD:6480464
CTD
G
Osmr
oncostatin M receptor
increases response to substance
ISO
2
56,080,700
56,121,463
RGD:6480464
CTD
G
Oxt
oxytocin/neurophysin 1 prepropeptide
increases expression
EXP
3
118,194,219
118,195,056
RGD:6480464
CTD
G
Padi2
peptidyl arginine deiminase, type II
decreases expression
ISO
5
159,762,824
159,805,399
RGD:6480464
CTD
G
Parp1
poly (ADP-ribose) polymerase 1
multiple interactions
ISO
13
96,309,670
96,341,486
RGD:6480464
CTD
G
Parp1
poly (ADP-ribose) polymerase 1
multiple interactions
ISO
13
96,309,670
96,341,486
RGD:6480464
CTD
G
Parp1
poly (ADP-ribose) polymerase 1
multiple interactions
ISO
13
96,309,670
96,341,486
RGD:6480464
CTD
G
Parp1
poly (ADP-ribose) polymerase 1
increases cleavage
ISO
13
96,309,670
96,341,486
RGD:6480464
CTD
G
Parp1
poly (ADP-ribose) polymerase 1
multiple interactions
ISO
13
96,309,670
96,341,486
RGD:6480464
CTD
G
Parp1
poly (ADP-ribose) polymerase 1
multiple interactions
ISO
13
96,309,670
96,341,486
RGD:6480464
CTD
G
Parp1
poly (ADP-ribose) polymerase 1
multiple interactions
ISO
13
96,309,670
96,341,486
RGD:6480464
CTD
G
Parp1
poly (ADP-ribose) polymerase 1
increases cleavage
ISO
13
96,309,670
96,341,486
RGD:6480464
CTD
G
Pcca
propionyl CoA carboxylase, alpha polypeptide
decreases expression
ISO
15
107,659,723
108,028,929
RGD:6480464
CTD
G
Pccb
propionyl CoA carboxylase, beta polypeptide
increases expression
EXP
8
105,946,482
105,996,472
RGD:6480464
CTD
G
Pcna
proliferating cell nuclear antigen
increases expression
ISO
3
120,008,715
120,012,589
RGD:6480464
CTD
G
Pcna
proliferating cell nuclear antigen
multiple interactions
ISO
3
120,008,715
120,012,589
RGD:6480464
CTD
G
Pcolce
procollagen C-endopeptidase enhancer
increases expression
ISO
12
19,672,505
19,678,821
RGD:6480464
CTD
G
Pdpk1
3-phosphoinositide dependent protein kinase-1
decreases response to substance
ISO
10
13,329,708
13,394,080
RGD:6480464
CTD
G
Pecam1
platelet/endothelial cell adhesion molecule 1
multiple interactions
ISO
10
96,056,220
96,057,232
RGD:6480464
CTD
G
Perp
PERP, TP53 apoptosis effector
increases expression
ISO
1
13,976,356
13,988,803
RGD:6480464
CTD
G
Phgdh
phosphoglycerate dehydrogenase
decreases expression
EXP
2
193,147,943
193,177,137
RGD:6480464
CTD
G
Pik3c2a
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
affects response to substance
ISO
1
174,430,831
174,537,706
RGD:6480464
CTD
G
Pklr
pyruvate kinase, liver and RBC
decreases expression
ISO
2
181,214,853
181,223,505
RGD:6480464
CTD
G
Pkm
pyruvate kinase, muscle
affects response to substance
ISO
8
63,486,492
63,508,016
RGD:6480464
CTD
G
Pkp2
plakophilin 2
decreases response to substance
ISO
11
86,553,493
86,584,425
RGD:6480464
CTD
G
Pla2g2a
phospholipase A2, group IIA (platelets, synovial fluid)
increases expression
EXP
5
157,654,786
157,657,360
RGD:6480464
CTD
G
Pla2g2d
phospholipase A2, group IID
increases expression
EXP
5
157,594,706
157,600,865
RGD:6480464
CTD
G
Plce1
phospholipase C, epsilon 1
decreases response to substance
ISO
1
242,794,858
243,103,437
RGD:6480464
CTD
G
Plcl1
phospholipase C-like 1
increases expression
EXP
9
54,207,542
54,546,228
RGD:6480464
CTD
G
Plk1
polo-like kinase 1
multiple interactions
ISO
1
181,002,811
181,012,741
RGD:6480464
CTD
G
Plk4
polo-like kinase 4
decreases expression
ISO
2
127,760,508
127,779,640
RGD:6480464
CTD
G
Pmp22
peripheral myelin protein 22
decreases response to substance
ISO
10
49,305,835
49,335,864
RGD:6480464
CTD
G
Polk
polymerase (DNA directed) kappa
decreases expression
ISO
2
26,952,022
27,012,088
RGD:6480464
CTD
G
Por
P450 (cytochrome) oxidoreductase
increases response to substance
ISO
12
22,078,629
22,097,301
RGD:6480464
CTD
G
Postn
periostin, osteoblast specific factor
increases expression
ISO
2
143,537,099
143,568,341
RGD:6480464
CTD
G
Ppap2a
phosphatidic acid phosphatase type 2A
decreases response to substance
ISO
2
44,183,290
44,247,787
RGD:6480464
CTD
G
Ppap2c
phosphatidic acid phosphatase type 2c
decreases expression
ISO
7
11,694,272
11,702,348
RGD:6480464
CTD
G
Ppib
peptidylprolyl isomerase B
affects response to substance
ISO
8
70,343,463
70,349,320
RGD:6480464
CTD
G
Ppp1cb
protein phosphatase 1, catalytic subunit, beta isozyme
affects response to substance
ISO
6
24,067,544
24,099,280
RGD:6480464
CTD
G
Ppp1r12a
protein phosphatase 1, regulatory subunit 12A
decreases expression
ISO
7
46,876,552
46,986,022
RGD:6480464
CTD
G
Ppp1r9a
protein phosphatase 1, regulatory subunit 9A
decreases expression
ISO
4
29,654,468
29,928,476
RGD:6480464
CTD
G
Prc1
protein regulator of cytokinesis 1
increases expression
ISO
1
136,112,674
136,133,720
RGD:6480464
CTD
G
Prdm4
PR domain containing 4
decreases expression
ISO
7
20,096,859
20,117,628
RGD:6480464
CTD
G
Prdx2
peroxiredoxin 2
affects response to substance
ISO
19
24,836,199
24,841,390
RGD:6480464
CTD
G
Prkce
protein kinase C, epsilon
affects response to substance
EXP
6
9,631,234
10,097,311
RGD:6480464
CTD
G
Prl2b1
Prolactin family 2, subfamily b, member 1
increases expression
ISO
17
44,180,979
44,188,002
RGD:6480464
CTD
G
Prom1
prominin 1
decreases response to substance
ISO
14
72,122,986
72,230,453
RGD:6480464
CTD
G
Prrg4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
decreases expression
ISO
3
90,174,070
90,198,654
RGD:6480464
CTD
G
Psap
prosaposin
decreases expression
ISO
20
27,595,048
27,621,574
RGD:6480464
CTD
G
Psma4
proteasome (prosome, macropain) subunit, alpha type 4
affects response to substance
ISO
8
58,508,643
58,516,103
RGD:6480464
CTD
G
Psmb1
proteasome (prosome, macropain) subunit, beta type 1
affects response to substance
ISO
1
54,369,775
54,388,816
RGD:6480464
CTD
G
Psmb6
proteasome (prosome, macropain) subunit, beta type 6
affects response to substance
ISO
10
57,370,397
57,372,704
RGD:6480464
CTD
G
Pten
phosphatase and tensin homolog
increases activity
ISO
1
236,771,027
236,837,261
RGD:6480464
CTD
G
Pten
phosphatase and tensin homolog
increases response to substance
ISO
1
236,771,027
236,837,261
RGD:6480464
CTD
G
Ptger4
prostaglandin E receptor 4 (subtype EP4)
decreases expression
EXP
2
54,423,280
54,433,907
RGD:6480464
CTD
G
Ptges3
prostaglandin E synthase 3 (cytosolic)
affects response to substance
ISO
7
1,351,206
1,368,857
RGD:6480464
CTD
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
ISO
13
64,427,288
64,432,978
RGD:6480464
CTD
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
ISO
13
64,427,288
64,432,978
RGD:6480464
CTD
G
Ptgs2
prostaglandin-endoperoxide synthase 2
decreases expression
ISO
13
64,427,288
64,432,978
RGD:6480464
CTD
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
ISO
13
64,427,288
64,432,978
RGD:6480464
CTD
G
Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression
ISO
13
64,427,288
64,432,978
RGD:6480464
CTD
G
Ptk6
protein tyrosine kinase 6
increases expression
ISO
3
170,336,505
170,345,096
RGD:6480464
CTD
G
Ptpn13
protein tyrosine phosphatase, non-receptor type 13
increases response to substance
ISO
14
7,298,209
7,433,464
RGD:6480464
CTD
G
Ptpn7
protein tyrosine phosphatase, non-receptor type 7
increases expression
ISO
13
48,094,119
48,105,707
RGD:6480464
CTD
G
Qrich1
glutamine-rich 1
increases phosphorylation
ISO
8
113,564,863
113,606,732
RGD:6480464
CTD
G
Qsox1
quiescin Q6 sulfhydryl oxidase 1
decreases expression
ISO
13
70,739,793
70,777,526
RGD:6480464
CTD
G
Rab34
RAB34, member RAS oncogene family
increases expression
ISO
10
64,443,111
64,447,315
RGD:6480464
CTD
G
Rac1
ras-related C3 botulinum toxin substrate 1
decreases expression
ISO
12
11,380,314
11,400,531
RGD:6480464
CTD
G
Rad23a
RAD23 homolog A (S. cerevisiae)
decreases expression
ISO
19
24,971,070
24,976,901
RGD:6480464
CTD
G
Raf1
v-raf-leukemia viral oncogene 1
multiple interactions
ISO
4
151,752,583
151,775,609
RGD:6480464
CTD
G
Ramp1
receptor (G protein-coupled) activity modifying protein 1
multiple interactions
ISO
9
90,402,493
90,450,038
RGD:6480464
CTD
G
Rapgef5
Rap guanine nucleotide exchange factor (GEF) 5
increases expression
ISO
6
144,949,908
145,030,090
RGD:6480464
CTD
G
Rarb
retinoic acid receptor, beta
increases expression
EXP
RGD:6480464
CTD
G
Rarb
retinoic acid receptor, beta
multiple interactions
EXP
RGD:6480464
CTD
G
Rb1
retinoblastoma 1
increases phosphorylation
ISO
15
53,828,881
53,962,099
RGD:6480464
CTD
G
Rb1
retinoblastoma 1
multiple interactions
ISO
15
53,828,881
53,962,099
RGD:6480464
CTD
G
Rbbp9
retinoblastoma binding protein 9
decreases expression
ISO
3
133,091,157
133,097,910
RGD:6480464
CTD
G
Rbp1
retinol binding protein 1, cellular
increases response to substance
ISO
8
103,605,870
103,627,390
RGD:6480464
CTD
G
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
multiple interactions
ISO
1
208,262,669
208,273,148
RGD:6480464
CTD
G
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
multiple interactions
ISO
1
208,262,669
208,273,148
RGD:6480464
CTD
G
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
multiple interactions
ISO
1
208,262,669
208,273,148
RGD:6480464
CTD
G
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
multiple interactions
ISO
1
208,262,669
208,273,148
RGD:6480464
CTD
G
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
multiple interactions
ISO
1
208,262,669
208,273,148
RGD:6480464
CTD
G
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
multiple interactions
ISO
1
208,262,669
208,273,148
RGD:6480464
CTD
G
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
decreases expression
ISO
1
208,262,669
208,273,148
RGD:6480464
CTD
G
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
multiple interactions
ISO
1
208,262,669
208,273,148
RGD:6480464
CTD
G
Rfc5
replication factor C (activator 1) 5
decreases expression
ISO
12
40,395,942
40,405,498
RGD:6480464
CTD
G
Rfx5
regulatory factor X, 5 (influences HLA class II expression)
decreases response to substance
ISO
2
189,855,438
189,862,953
RGD:6480464
CTD
G
Rfxank
regulatory factor X-associated ankyrin-containing protein
affects response to substance
ISO
16
19,764,913
19,772,281
RGD:6480464
CTD
G
RGD1306151
similar to hypothetical protein DKFZp761D0211
multiple interactions
ISO
4
172,149,689
172,190,878
RGD:6480464
CTD
G
RGD1359529
similar to chromosome 1 open reading frame 63
affects response to substance
ISO
5
153,698,946
153,702,685
RGD:6480464
CTD
G
Rhot2
ras homolog family member T2
affects response to substance
ISO
10
15,104,341
15,110,135
RGD:6480464
CTD
G
Rnf19a
ring finger protein 19A, E3 ubiquitin protein ligase
decreases expression
ISO
7
71,763,837
71,803,435
RGD:6480464
CTD
G
Rock1
Rho-associated coiled-coil containing protein kinase 1
increases expression
ISO
18
1,391,751
1,511,865
RGD:6480464
CTD
G
Rpl10
ribosomal protein L10
affects response to substance
ISO
X
160,336,632
160,338,842
RGD:6480464
CTD
G
Rpl22l1
ribosomal protein L22 like 1
decreases expression
ISO
2
116,168,790
116,170,726
RGD:6480464
CTD
G
Rpl23a
ribosomal protein L23a
decreases response to substance
ISO
10
64,451,931
64,454,617
RGD:6480464
CTD
G
Rplp1
ribosomal protein, large, P1
decreases response to substance
ISO
8
66,046,220
66,047,553
RGD:6480464
CTD
G
Rrm2
ribonucleotide reductase M2
multiple interactions
ISO
6
42,350,541
42,356,748
RGD:6480464
CTD
G
RT1-EC2
RT1 class Ib, locus EC2
increases expression
EXP
RGD:6480464
CTD
G
Rtkn
rhotekin
decreases response to substance
ISO
4
117,348,330
117,363,967
RGD:6480464
CTD
G
Rtkn
rhotekin
multiple interactions
ISO
4
117,348,330
117,363,967
RGD:6480464
CTD
G
Ruvbl2
RuvB-like 2 (E. coli)
decreases expression
ISO
1
95,894,029
95,906,885
RGD:6480464
CTD
G
S100a4
S100 calcium-binding protein A4
increases expression
ISO
2
182,885,070
182,887,380
RGD:6480464
CTD
G
Scg5
secretogranin V (7B2 protein)
affects response to substance
ISO
3
99,629,194
99,674,523
RGD:6480464
CTD
G
Scg5
secretogranin V (7B2 protein)
increases expression
EXP
3
99,629,194
99,674,523
RGD:6480464
CTD
G
Scube2
signal peptide, CUB domain, EGF-like 2
multiple interactions
ISO
1
167,423,473
167,490,273
RGD:6480464
CTD
G
Sdc2
syndecan 2
increases expression
ISO
7
68,290,558
68,405,183
RGD:6480464
CTD
G
Selp
selectin P
increases expression
EXP
13
79,886,614
79,922,180
RGD:6480464
CTD
G
Serpina3n
serine (or cysteine) peptidase inhibitor, clade A, member 3N
increases expression
EXP
6
128,461,775
128,469,309
RGD:6480464
CTD
G
Serpinb2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
affects response to substance
ISO
13
13,632,596
13,641,605
RGD:6480464
CTD
G
Serpinb6b
serine (or cysteine) peptidase inhibitor, clade B, member 6b
increases expression
EXP
17
37,816,548
37,834,299
RGD:6480464
CTD
G
Serpine1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
affects response to substance
ISO
12
20,931,996
20,942,374
RGD:6480464
CTD
G
Serpinf1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
increases expression
ISO
10
62,713,441
62,739,444
RGD:6480464
CTD
G
Sgcb
sarcoglycan, beta (dystrophin-associated glycoprotein)
affects response to substance
ISO
14
36,959,920
36,974,916
RGD:6480464
CTD
G
Sgk1
serum/glucocorticoid regulated kinase 1
decreases expression
EXP
1
23,501,257
23,506,651
RGD:6480464
CTD
G
Sh3bp2
SH3-domain binding protein 2
decreases expression
ISO
14
81,818,728
81,855,875
RGD:6480464
CTD
G
Sigmar1
sigma non-opioid intracellular receptor 1
increases expression
EXP
5
59,162,537
59,165,315
RGD:6480464
CTD
G
Sirt1
sirtuin 1
multiple interactions
ISO
20
25,675,302
25,686,494
RGD:6480464
CTD
G
Sirt1
sirtuin 1
decreases expression
ISO
20
25,675,302
25,686,494
RGD:6480464
CTD
G
Skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
affects response to substance
ISO
2
58,769,164
58,797,229
RGD:6480464
CTD
G
Slc12a2
solute carrier family 12 (sodium/potassium/chloride transporters), member 2
decreases response to substance
ISO
18
53,673,215
53,741,352
RGD:6480464
CTD
G
Slc1a1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
decreases expression
EXP
1
232,469,746
232,549,584
RGD:6480464
CTD
G
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
decreases expression
EXP
3
87,870,558
87,992,401
RGD:6480464
CTD
G
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
decreases expression
EXP
2
58,270,236
58,347,613
RGD:6480464
CTD
G
Slc22a18
solute carrier family 22, member 18
decreases response to substance
ISO
1
203,852,313
203,876,165
RGD:6480464
CTD
G
Slc22a3
solute carrier family 22 (extraneuronal monoamine transporter), member 3
affects response to substance
ISO
1
42,690,158
42,781,895
RGD:6480464
CTD
G
Slc22a3
solute carrier family 22 (extraneuronal monoamine transporter), member 3
increases expression
EXP
1
42,690,158
42,781,895
RGD:6480464
CTD
G
Slc22a7
solute carrier family 22 (organic anion transporter), member 7
increases transport
ISO
9
9,934,309
9,940,107
RGD:6480464
CTD
G
Slc25a4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
decreases expression
ISO
16
49,353,476
49,357,271
RGD:6480464
CTD
G
Slc28a2
solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
decreases expression
EXP
3
109,350,531
109,372,027
RGD:6480464
CTD
G
Slc31a1
solute carrier family 31 (copper transporters), member 1
increases expression
ISO
5
79,359,420
79,385,988
RGD:6480464
CTD
G
Slc6a20
solute carrier family 6 (proline IMINO transporter), member 20
increases expression
EXP
8
128,412,080
128,452,212
RGD:6480464
CTD
G
Slc9a1
solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
decreases activity
ISO
5
151,680,696
151,748,460
RGD:6480464
CTD
G
Snapc1
small nuclear RNA activating complex, polypeptide 1
increases response to substance
ISO
6
96,479,145
96,505,377
RGD:6480464
CTD
G
Sned1
sushi, nidogen and EGF-like domains 1
increases expression
EXP
9
92,509,499
92,568,597
RGD:6480464
CTD
G
Snrnp25
small nuclear ribonucleoprotein 25 (U11/U12)
affects response to substance
ISO
10
15,667,569
15,671,373
RGD:6480464
CTD
G
Snrpa1
small nuclear ribonucleoprotein polypeptide A'
affects response to substance
ISO
1
120,490,921
120,503,974
RGD:6480464
CTD
G
Snx10
sorting nexin 10
affects response to substance
ISO
4
79,789,556
79,853,215
RGD:6480464
CTD
G
Sp140
SP140 nuclear body protein
affects response to substance
ISO
9
84,281,385
84,337,123
RGD:6480464
CTD
G
Sparc
secreted protein, acidic, cysteine-rich (osteonectin)
increases expression
ISO
10
40,809,730
40,831,481
RGD:6480464
CTD
G
Spint2
serine peptidase inhibitor, Kunitz type, 2
decreases expression
ISO
1
84,393,845
84,416,299
RGD:6480464
CTD
G
Srgn
serglycin
affects response to substance
ISO
20
29,746,729
29,761,072
RGD:6480464
CTD
G
Sri
sorcin
decreases response to substance
ISO
RGD:6480464
CTD
G
Srpr
signal recognition particle receptor ('docking protein')
affects response to substance
ISO
8
34,992,187
34,998,270
RGD:6480464
CTD
G
Stat3
signal transducer and activator of transcription 3 (acute-phase response factor)
multiple interactions
ISO
10
89,821,078
89,872,970
RGD:6480464
CTD
G
Stat3
signal transducer and activator of transcription 3 (acute-phase response factor)
decreases response to substance
ISO
10
89,821,078
89,872,970
RGD:6480464
CTD
G
Stat3
signal transducer and activator of transcription 3 (acute-phase response factor)
decreases activity
ISO
10
89,821,078
89,872,970
RGD:6480464
CTD
G
Stc1
stanniocalcin 1
affects response to substance
ISO
15
49,566,885
49,577,539
RGD:6480464
CTD
G
Stip1
stress-induced phosphoprotein 1
increases expression
ISO
1
209,693,427
209,712,779
RGD:6480464
CTD
G
Stmn1
stathmin 1
affects response to substance
ISO
5
153,226,420
153,232,084
RGD:6480464
CTD
G
Stra6
stimulated by retinoic acid 6
increases expression
EXP
8
61,920,772
61,939,791
RGD:6480464
CTD
G
Sub1
SUB1 homolog (S. cerevisiae)
decreases expression
ISO
2
61,418,076
61,430,139
RGD:6480464
CTD
G
Sucla2
succinate-CoA ligase, ADP-forming, beta subunit
affects response to substance
ISO
15
54,214,262
54,267,830
RGD:6480464
CTD
G
Sult2a1
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
increases expression
EXP
1
75,632,632
75,708,022
RGD:6480464
CTD
G
Sult2a6
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6
increases expression
EXP
1
74,553,799
74,605,247
RGD:6480464
CTD
G
Tac1
tachykinin, precursor 1
multiple interactions
EXP
4
32,649,666
32,657,632
RGD:6480464
CTD
G
Tac1
tachykinin, precursor 1
increases expression
EXP
4
32,649,666
32,657,632
RGD:6480464
CTD
G
Tac1
tachykinin, precursor 1
increases secretion
EXP
4
32,649,666
32,657,632
RGD:6480464
CTD
G
Tac1
tachykinin, precursor 1
multiple interactions
EXP
4
32,649,666
32,657,632
RGD:6480464
CTD
G
Tacc3
transforming, acidic coiled-coil containing protein 3
decreases expression
ISO
14
82,746,460
82,760,864
RGD:6480464
CTD
G
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
increases expression
ISO
20
4,790,363
4,800,730
RGD:6480464
CTD
G
Tdg
thymine-DNA glycosylase
affects response to substance
ISO
7
23,300,450
23,320,095
RGD:6480464
CTD
G
Tert
telomerase reverse transcriptase
multiple interactions
ISO
1
30,445,180
30,465,942
RGD:6480464
CTD
G
Tert
telomerase reverse transcriptase
multiple interactions
ISO
1
30,445,180
30,465,942
RGD:6480464
CTD
G
Tert
telomerase reverse transcriptase
decreases expression
ISO
1
30,445,180
30,465,942
RGD:6480464
CTD
G
Tert
telomerase reverse transcriptase
multiple interactions
ISO
1
30,445,180
30,465,942
RGD:6480464
CTD
G
Tfap2a
transcription factor AP-2 alpha
increases response to substance
ISO
17
30,017,580
30,034,852
RGD:6480464
CTD
G
Tfap2a
transcription factor AP-2 alpha
increases expression
ISO
17
30,017,580
30,034,852
RGD:6480464
CTD
G
Tfap2c
transcription factor AP-2 gamma
decreases expression
ISO
3
163,459,283
163,467,166
RGD:6480464
CTD
G
Tff1
trefoil factor 1
increases response to substance
ISO
20
9,526,674
9,530,534
RGD:6480464
CTD
G
Tfpi2
tissue factor pathway inhibitor 2
affects response to substance
ISO
4
28,807,080
28,811,502
RGD:6480464
CTD
G
Thnsl2
threonine synthase-like 2 (S. cerevisiae)
multiple interactions
ISO
4
104,329,517
104,348,465
RGD:6480464
CTD
G
Thy1
Thy-1 cell surface antigen
increases expression
ISO
8
47,027,721
47,031,857
RGD:6480464
CTD
G
Tia1
TIA1 cytotoxic granule-associated RNA binding protein
affects response to substance
ISO
4
120,590,164
120,617,530
RGD:6480464
CTD
G
Timm13
translocase of inner mitochondrial membrane 13 homolog (yeast)
affects response to substance
ISO
7
10,319,959
10,321,062
RGD:6480464
CTD
G
Timm22
translocase of inner mitochondrial membrane 22 homolog (yeast)
increases expression
ISO
10
67,762,261
67,770,013
RGD:6480464
CTD
G
Tjp3
tight junction protein 3
decreases response to substance
ISO
7
9,917,359
9,930,081
RGD:6480464
CTD
G
Tk1
thymidine kinase 1, soluble
increases mutagenesis
ISO
RGD:6480464
CTD
G
Tlr4
toll-like receptor 4
multiple interactions
ISO
5
83,564,100
83,577,735
RGD:6480464
CTD
G
Tlr4
toll-like receptor 4
affects response to substance
ISO
5
83,564,100
83,577,735
RGD:6480464
CTD
G
Tmem134
transmembrane protein 134
affects response to substance
ISO
1
206,708,930
206,714,409
RGD:6480464
CTD
G
Tmem135
transmembrane protein 135
affects response to substance
ISO
1
145,664,796
145,894,704
RGD:6480464
CTD
G
Tmem168
transmembrane protein 168
affects response to substance
ISO
4
39,012,323
39,039,671
RGD:6480464
CTD
G
Tmem176a
transmembrane protein 176A
decreases expression
EXP
4
76,919,918
76,923,598
RGD:6480464
CTD
G
Tmem243
transmembrane protein 243, mitochondrial
decreases response to substance
ISO
4
21,369,696
21,387,544
RGD:6480464
CTD
G
Tmem243
transmembrane protein 243, mitochondrial
increases expression
ISO
4
21,369,696
21,387,544
RGD:6480464
CTD
G
Tmem246
transmembrane protein 246
affects response to substance
ISO
5
66,327,277
66,329,047
RGD:6480464
CTD
G
Tnf
tumor necrosis factor
multiple interactions
ISO
20
3,661,000
3,663,618
RGD:6480464
CTD
G
Tnf
tumor necrosis factor
multiple interactions
ISO
20
3,661,000
3,663,618
RGD:6480464
CTD
G
Tnf
tumor necrosis factor
increases expression
ISO
20
3,661,000
3,663,618
RGD:6480464
CTD
G
Tnf
tumor necrosis factor
increases secretion
ISO
20
3,661,000
3,663,618
RGD:6480464
CTD
G
Tnf
tumor necrosis factor
multiple interactions
ISO
20
3,661,000
3,663,618
RGD:6480464
CTD
G
Tnf
tumor necrosis factor
increases expression
EXP
20
3,661,000
3,663,618
RGD:6480464
CTD
G
Tnfrsf10b
tumor necrosis factor receptor superfamily, member 10b
increases expression
ISO
15
50,138,439
50,163,254
RGD:6480464
CTD
G
Tnfrsf10b
tumor necrosis factor receptor superfamily, member 10b
multiple interactions
ISO
15
50,138,439
50,163,254
RGD:6480464
CTD
G
Tnfrsf1a
tumor necrosis factor receptor superfamily, member 1a
affects response to substance
ISO
4
162,172,563
162,185,252
RGD:6480464
CTD
G
Tnfsf10
tumor necrosis factor (ligand) superfamily, member 10
increases expression
ISO
2
113,204,303
113,221,550
RGD:6480464
CTD
G
Tnfsf13
tumor necrosis factor (ligand) superfamily, member 13
increases expression
ISO
10
56,499,945
56,502,928
RGD:6480464
CTD
G
Tnfsf13b
tumor necrosis factor (ligand) superfamily, member 13b
increases expression
ISO
16
84,837,266
84,856,103
RGD:6480464
CTD
G
Tnp2
transition protein 2
increases expression
EXP
10
4,816,612
4,817,340
RGD:6480464
CTD
G
Top1
topoisomerase (DNA) I
decreases expression
ISO
3
151,428,931
151,512,884
RGD:6480464
CTD
G
Top2a
topoisomerase (DNA) II alpha
increases response to substance
ISO
10
87,771,337
87,800,960
RGD:6480464
CTD
G
Top2a
topoisomerase (DNA) II alpha
multiple interactions
ISO
10
87,771,337
87,800,960
RGD:6480464
CTD
G
Tp53
tumor protein p53
multiple interactions
ISO
10
56,399,721
56,411,150
RGD:6480464
CTD
G
Tp53
tumor protein p53
multiple interactions
ISO
10
56,399,721
56,411,150
RGD:6480464
CTD
G
Tp53
tumor protein p53
multiple interactions
ISO
10
56,399,721
56,411,150
RGD:6480464
CTD
G
Tp53
tumor protein p53
decreases expression
ISO
10
56,399,721
56,411,150
RGD:6480464
CTD
G
Tp53
tumor protein p53
increases expression
ISO
10
56,399,721
56,411,150
RGD:6480464
CTD
G
Tp53
tumor protein p53
increases expression
ISO
10
56,399,721
56,411,150
RGD:6480464
CTD
G
Tp53
tumor protein p53
increases expression
ISO
10
56,399,721
56,411,150
RGD:6480464
CTD
G
Tp53
tumor protein p53
multiple interactions
ISO
10
56,399,721
56,411,150
RGD:6480464
CTD
G
Tp53
tumor protein p53
decreases response to substance
ISO
10
56,399,721
56,411,150
RGD:6480464
CTD
G
Tp53
tumor protein p53
increases expression
ISO
10
56,399,721
56,411,150
RGD:6480464
CTD
G
Tp53
tumor protein p53
increases expression
ISO
10
56,399,721
56,411,150
RGD:6480464
CTD
G
Tpd52
tumor protein D52
decreases expression
ISO
2
94,850,203
94,880,802
RGD:6480464
CTD
G
Traf2
Tnf receptor-associated factor 2
affects response to substance
ISO
3
3,692,740
3,717,332
RGD:6480464
CTD
G
Trim2
tripartite motif-containing 2
affects response to substance
ISO
2
175,908,880
175,974,709
RGD:6480464
CTD
G
Triobp
TRIO and F-actin binding protein
increases expression
ISO
7
116,917,008
116,969,695
RGD:6480464
CTD
G
Trpc3
transient receptor potential cation channel, subfamily C, member 3
increases expression
ISO
2
123,117,180
123,184,016
RGD:6480464
CTD
G
Tsc22d3
TSC22 domain family, member 3
increases expression
EXP
X
128,336,408
128,340,027
RGD:6480464
CTD
G
Tsnax
translin-associated factor X
increases expression
EXP
RGD:6480464
CTD
G
Tubb5
tubulin, beta 5 class I
increases response to substance
ISO
20
3,060,224
3,090,776
RGD:6480464
CTD
G
Tyms
thymidylate synthetase
multiple interactions
ISO
9
112,604,912
112,617,706
RGD:6480464
CTD
G
Tyms
thymidylate synthetase
affects expression
ISO
9
112,604,912
112,617,706
RGD:6480464
CTD
G
Tyms
thymidylate synthetase
multiple interactions
ISO
9
112,604,912
112,617,706
RGD:6480464
CTD
G
Tyms
thymidylate synthetase
increases expression
ISO
9
112,604,912
112,617,706
RGD:6480464
CTD
G
Tyms
thymidylate synthetase
multiple interactions
ISO
9
112,604,912
112,617,706
RGD:6480464
CTD
G
Ube2l6
ubiquitin-conjugating enzyme E2L 6
affects response to substance
ISO
3
68,000,239
68,016,331
RGD:6480464
CTD
G
Uchl1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
increases expression
EXP
14
44,114,392
44,124,947
RGD:6480464
CTD
G
Uchl5
ubiquitin carboxyl-terminal hydrolase L5
increases expression
EXP
13
57,605,912
57,643,050
RGD:6480464
CTD
G
Umps
uridine monophosphate synthetase
decreases expression
ISO
11
68,619,835
68,630,244
RGD:6480464
CTD
G
Ung
uracil-DNA glycosylase
affects response to substance
ISO
12
43,520,629
43,528,873
RGD:6480464
CTD
G
Urod
uroporphyrinogen decarboxylase
decreases response to substance
ISO
5
137,296,410
137,300,496
RGD:6480464
CTD
G
Usp5
ubiquitin specific peptidase 5 (isopeptidase T)
decreases expression
ISO
4
160,937,706
160,952,769
RGD:6480464
CTD
G
Vamp8
vesicle-associated membrane protein 8
affects response to substance
ISO
4
105,692,451
105,694,908
RGD:6480464
CTD
G
Vcam1
vascular cell adhesion molecule 1
affects response to substance
ISO
2
212,277,654
212,297,376
RGD:6480464
CTD
G
Vcan
versican
increases expression
EXP
2
19,712,629
19,801,443
RGD:6480464
CTD
G
Vegfa
vascular endothelial growth factor A
multiple interactions
ISO
9
10,520,730
10,536,071
RGD:6480464
CTD
G
Vegfa
vascular endothelial growth factor A
decreases expression
ISO
9
10,520,730
10,536,071
RGD:6480464
CTD
G
Vegfa
vascular endothelial growth factor A
multiple interactions
ISO
9
10,520,730
10,536,071
RGD:6480464
CTD
G
Wdr35
WD repeat domain 35
decreases expression
EXP
6
32,522,578
32,523,842
RGD:6480464
CTD
G
Wdr61
WD repeat domain 61
affects response to substance
ISO
8
58,268,875
58,286,551
RGD:6480464
CTD
G
Wdr8
WD repeat domain 8
affects response to substance
ISO
5
171,103,735
171,109,776
RGD:6480464
CTD
G
Wif1
Wnt inhibitory factor 1
increases response to substance
ISO
7
60,330,517
60,400,697
RGD:6480464
CTD
G
Wsb2
WD repeat and SOCS box-containing 2
affects response to substance
ISO
12
40,406,890
40,427,103
RGD:6480464
CTD
G
Xiap
X-linked inhibitor of apoptosis
multiple interactions
ISO
X
3,011,520
3,047,798
RGD:6480464
CTD
G
Xiap
X-linked inhibitor of apoptosis
multiple interactions
ISO
X
3,011,520
3,047,798
RGD:6480464
CTD
G
Xiap
X-linked inhibitor of apoptosis
affects expression
ISO
X
3,011,520
3,047,798
RGD:6480464
CTD
G
Xiap
X-linked inhibitor of apoptosis
decreases expression
ISO
X
3,011,520
3,047,798
RGD:6480464
CTD
G
Xiap
X-linked inhibitor of apoptosis
decreases expression
ISO
X
3,011,520
3,047,798
RGD:6480464
CTD
G
Xpo1
exportin 1, CRM1 homolog (yeast)
decreases expression
ISO
14
103,943,249
103,978,717
RGD:6480464
CTD
G
Xrcc5
X-ray repair complementing defective repair in Chinese hamster cells 5
decreases expression
ISO
9
71,472,459
71,581,936
RGD:6480464
CTD
G
Ywhaq
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
increases expression
ISO
6
41,945,769
41,976,123
RGD:6480464
CTD
G
Ywhaz
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
increases expression
EXP
7
72,283,825
72,306,126
RGD:6480464
CTD
G
Zfp36l2
zinc finger protein 36, C3H type-like 2
affects response to substance
ISO
6
7,530,948
7,534,988
RGD:6480464
CTD
G
Zfp385a
zinc finger protein 385A
increases expression
ISO
7
142,222,824
142,250,176
RGD:6480464
CTD
G
Zfp52
zinc finger protein 52
decreases expression
ISO
1
59,540,774
59,568,607
RGD:6480464
CTD
G
Zranb2
zinc finger, RAN-binding domain containing 2
decreases expression
ISO
2
255,645,572
255,659,078
RGD:6480464
CTD
Term paths to the root one longest all shortest one shortest all one shortest and longest all longest