okadaic acid - Ontology Report - Rat Genome Database

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ONTOLOGY REPORT - ANNOTATIONS

Term:	okadaic acid	go back to main search page
Accession:	CHEBI:44658	browse the term
Definition:	A polycyclic ether that has formula C44H68O13.
Synonyms:	exact_synonym:	(2R)-2-hydroxy-3-{(2S,5R,6R,8S)-5-hydroxy-8-[(2R,3E)-4-((2R,4a'R,5R,6'S,8'R,8a'S)-8'-hydroxy-6'-{(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl}-7'-methylideneoctahydro-3H,3'H-spiro[furan-2,2'-pyrano[3,2-b]pyran]-5-yl)but-3-en-2-yl]-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl}-2-methylpropanoic acid
	related_synonym:	9,10-Deepithio-9,10-didehydroacanthifolicin; C44H68O13; InChI=1S/C44H68O13/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49)/b10-9+/t26-,27-,28+,30+,31+,32+,33-,34+,35-,36-,37+,38+,39-,41-,42+,43-,44-/m1/s1; InChIKey=QNDVLZJODHBUFM-WFXQOWMNSA-N; [H][C@]1(CC[C@@H](O)[C@]2(O1)O[C@@]([H])(CC(C)=C2)[C@H](C)\\C=C\\[C@@]1([H])CC[C@@]2(CC[C@@]3([H])O[C@]([H])([C@@H](O)C[C@H](C)[C@@]4([H])O[C@@]5(CCCCO5)CC[C@H]4C)C(=C)[C@@H](O)[C@]3([H])O2)O1)C[C@@](C)(O)C(O)=O
	alt_id:	CHEBI:44655; CHEBI:7733
	xref_casrn:	78111-17-8
	xref:	Beilstein:4640246 "Beilstein Registry Number"; Beilstein:4900372 "Beilstein Registry Number"; Beilstein:5471989 "Beilstein Registry Number"; ChEMBL:118873 "ChEMBL COMPOUND"; ChemIDplus:78111-17-8 "CAS Registry Number"; DrugBank:DB02169 "DrugBank"
	xref_mesh:	MESH:D019319

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okadaic acid
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Aanat	aralkylamine N-acetyltransferase		decreases activity	EXP	10	106,709,371	106,713,683	RGD:6480464	CTD
G	Aanat	aralkylamine N-acetyltransferase		decreases expression	EXP	10	106,709,371	106,713,683	RGD:6480464	CTD
G	Abcb1b	ATP-binding cassette, subfamily B (MDR/TAP), member 1B		decreases response to substance	EXP	4	21,829,489	21,912,239	RGD:6480464	CTD
G	Abl1	c-abl oncogene 1, non-receptor tyrosine kinase		multiple interactions	ISO	3	10,804,594	10,907,162	RGD:6480464	CTD
G	Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)		multiple interactions	ISO	19	54,738,556	54,750,349	RGD:6480464	CTD
G	Akt1	v-akt murine thymoma viral oncogene homolog 1		multiple interactions	ISO	6	137,640,482	137,657,552	RGD:6480464	CTD
G	Akt1	v-akt murine thymoma viral oncogene homolog 1		multiple interactions	ISO	6	137,640,482	137,657,552	RGD:6480464	CTD
G	Akt1	v-akt murine thymoma viral oncogene homolog 1		multiple interactions	ISO	6	137,640,482	137,657,552	RGD:6480464	CTD
G	Aldh1a1	aldehyde dehydrogenase 1 family, member A1		multiple interactions	ISO	1	223,731,675	223,773,285	RGD:6480464	CTD
G	Aldh1l1	aldehyde dehydrogenase 1 family, member L1		increases phosphorylation	ISO				RGD:6480464	CTD
G	Aldoa	aldolase A, fructose-bisphosphate		decreases expression	ISO	1	185,970,658	185,974,615	RGD:6480464	CTD
G	Anxa5	annexin A5		multiple interactions	ISO	2	122,949,210	122,979,757	RGD:6480464	CTD
G	App	amyloid beta (A4) precursor protein		multiple interactions	ISO	11	24,457,855	24,693,851	RGD:6480464	CTD
G	Atp5a1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle		decreases expression	ISO	18	74,735,267	74,743,088	RGD:6480464	CTD
G	Atp5d	ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit		multiple interactions	ISO	7	11,072,820	11,075,906	RGD:6480464	CTD
G	Atp5d	ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit		decreases expression	ISO	7	11,072,820	11,075,906	RGD:6480464	CTD
G	Bax	Bcl2-associated X protein		affects localization	ISO	1	95,933,023	95,938,176	RGD:6480464	CTD
G	Bax	Bcl2-associated X protein		multiple interactions	ISO	1	95,933,023	95,938,176	RGD:6480464	CTD
G	Bax	Bcl2-associated X protein		increases expression	EXP	1	95,933,023	95,938,176	RGD:6480464	CTD
G	Bax	Bcl2-associated X protein		multiple interactions	EXP	1	95,933,023	95,938,176	RGD:6480464	CTD
G	Bax	Bcl2-associated X protein		decreases expression	ISO	1	95,933,023	95,938,176	RGD:6480464	CTD
G	Bcat2	branched chain amino acid transaminase 2, mitochondrial		multiple interactions	ISO	1	96,038,287	96,055,622	RGD:6480464	CTD
G	Bcl2	B-cell CLL/lymphoma 2		decreases expression	ISO	13	12,730,736	12,905,108	RGD:6480464	CTD
G	Bgn	biglycan		multiple interactions	ISO	X	159,380,557	159,393,409	RGD:6480464	CTD
G	Blvrb	biliverdin reductase B (flavin reductase (NADPH))		multiple interactions	ISO	1	82,528,943	82,546,606	RGD:6480464	CTD
G	Cacybp	calcyclin binding protein		decreases expression	ISO	13	75,623,161	75,633,644	RGD:6480464	CTD
G	Calm1	calmodulin 1		multiple interactions	ISO	6	124,477,601	124,485,669	RGD:6480464	CTD
G	Car13	carbonic anhydrase 13		increases expression	ISO	2	88,271,908	88,309,336	RGD:6480464	CTD
G	Casp3	caspase 3		multiple interactions	ISO	16	48,944,226	48,962,420	RGD:6480464	CTD
G	Casp3	caspase 3		multiple interactions	EXP	16	48,944,226	48,962,420	RGD:6480464	CTD
G	Casp3	caspase 3		increases activity	EXP	16	48,944,226	48,962,420	RGD:6480464	CTD
G	Casp3	caspase 3		increases activity	EXP	16	48,944,226	48,962,420	RGD:6480464	CTD
G	Casp7	caspase 7		multiple interactions	ISO	1	262,689,300	262,721,591	RGD:6480464	CTD
G	Casp8	caspase 8		multiple interactions	ISO	9	57,389,353	57,437,803	RGD:6480464	CTD
G	Casp9	caspase 9, apoptosis-related cysteine peptidase		multiple interactions	ISO	5	160,704,234	160,721,796	RGD:6480464	CTD
G	Ccna1	cyclin A1		affects expression	ISO	2	144,275,211	144,285,196	RGD:6480464	CTD
G	Ccnb2	cyclin B2		affects expression	ISO	8	74,892,108	74,906,181	RGD:6480464	CTD
G	Cd9	CD9 molecule		multiple interactions	ISO	4	162,279,462	162,312,889	RGD:6480464	CTD
G	Cdk1	cyclin-dependent kinase 1		decreases expression	ISO	20	20,018,044	20,044,030	RGD:6480464	CTD
G	Cdk2	cyclin dependent kinase 2		decreases expression	ISO	7	2,000,196	2,007,682	RGD:6480464	CTD
G	Cfl1	cofilin 1, non-muscle		increases expression	ISO	1	208,133,876	208,137,408	RGD:6480464	CTD
G	Cftr	cystic fibrosis transmembrane conductance regulator		decreases activity	ISO	4	43,874,852	44,041,870	RGD:6480464	CTD
G	Chchd3	coiled-coil-helix-coiled-coil-helix domain containing 3		decreases expression	ISO	4	59,891,615	60,170,903	RGD:6480464	CTD
G	Chrna7	cholinergic receptor, nicotinic, alpha 7 (neuronal)		multiple interactions	ISO	1	117,587,580	117,716,267	RGD:6480464	CTD
G	Chrnb2	cholinergic receptor, nicotinic, beta 2 (neuronal)		multiple interactions	ISO	2	181,961,373	181,969,581	RGD:6480464	CTD
G	Clns1a	chloride channel, nucleotide-sensitive, 1A		decreases expression	ISO	1	154,946,713	154,966,947	RGD:6480464	CTD
G	Clta	clathrin, light chain A		multiple interactions	ISO	5	60,484,437	60,502,432	RGD:6480464	CTD
G	Col1a2	collagen, type I, alpha 2		multiple interactions	ISO	4	29,393,645	29,428,572	RGD:6480464	CTD
G	Col6a1	collagen, type VI, alpha 1		multiple interactions	ISO	20	12,320,102	12,338,500	RGD:6480464	CTD
G	Col8a1	collagen, type VIII, alpha 1		multiple interactions	ISO	11	43,604,994	43,733,870	RGD:6480464	CTD
G	Comt	catechol-O-methyltransferase		decreases expression	ISO	11	84,561,591	84,581,713	RGD:6480464	CTD
G	Comt	catechol-O-methyltransferase		multiple interactions	ISO	11	84,561,591	84,581,713	RGD:6480464	CTD
G	Crebbp	CREB binding protein		increases phosphorylation	ISO	10	11,598,680	11,724,122	RGD:6480464	CTD
G	Ctnnb1	catenin (cadherin associated protein), beta 1		increases phosphorylation	ISO	8	125,978,161	125,987,670	RGD:6480464	CTD
G	Ctsb	cathepsin B		multiple interactions	ISO	15	42,402,829	42,423,701	RGD:6480464	CTD
G	Ctsl1	cathepsin L1		multiple interactions	ISO	17	6,288,013	6,294,174	RGD:6480464	CTD
G	Cxcl12	chemokine (C-X-C motif) ligand 12		multiple interactions	ISO	4	153,503,576	153,516,423	RGD:6480464	CTD
G	Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1		multiple interactions	ISO	6	2,548,224	2,553,767	RGD:6480464	CTD
G	Cyp4a1	cytochrome P450, family 4, subfamily a, polypeptide 1		multiple interactions	EXP	5	135,901,653	135,915,754	RGD:6480464	CTD
G	Dlg1	discs, large homolog 1 (Drosophila)		multiple interactions	ISO	11	70,735,283	70,930,374	RGD:6480464	CTD
G	Dmp1	dentin matrix acidic phosphoprotein 1		increases expression	ISO	14	6,637,127	6,644,100	RGD:6480464	CTD
G	Dstn	destrin		decreases expression	ISO	3	132,358,484	132,385,198	RGD:6480464	CTD
G	Esr1	estrogen receptor 1		multiple interactions	ISO	1	35,523,680	35,759,891	RGD:6480464	CTD
G	Esr1	estrogen receptor 1		decreases expression	ISO	1	35,523,680	35,759,891	RGD:6480464	CTD
G	Esr1	estrogen receptor 1		multiple interactions	ISO	1	35,523,680	35,759,891	RGD:6480464	CTD
G	Fau	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed		multiple interactions	ISO	1	208,695,065	208,696,580	RGD:6480464	CTD
G	Fgfr4	fibroblast growth factor receptor 4		decreases phosphorylation	ISO	17	15,512,144	15,527,348	RGD:6480464	CTD
G	Fos	FBJ osteosarcoma oncogene		multiple interactions	EXP	6	109,559,135	109,562,001	RGD:6480464	CTD
G	Fos	FBJ osteosarcoma oncogene		increases expression	ISO	6	109,559,135	109,562,001	RGD:6480464	CTD
G	Fosl1	fos-like antigen 1		increases expression	ISO	1	208,090,612	208,099,118	RGD:6480464	CTD
G	Fstl1	follistatin-like 1		multiple interactions	ISO	11	64,681,814	64,735,673	RGD:6480464	CTD
G	Gja1	gap junction protein, alpha 1		increases expression	ISO	20	35,409,815	35,422,262	RGD:6480464	CTD
G	Gja1	gap junction protein, alpha 1		multiple interactions	ISO	20	35,409,815	35,422,262	RGD:6480464	CTD
G	Gjb2	gap junction protein, beta 2		increases expression	ISO	15	36,153,526	36,159,490	RGD:6480464	CTD
G	Gjb5	gap junction protein, beta 5		decreases expression	ISO	5	146,802,849	146,803,664	RGD:6480464	CTD
G	Glo1	glyoxalase 1		decreases expression	ISO	20	8,900,984	8,919,001	RGD:6480464	CTD
G	Glo1	glyoxalase 1		multiple interactions	ISO	20	8,900,984	8,919,001	RGD:6480464	CTD
G	Gpc4	glypican 4		multiple interactions	ISO	X	138,966,579	139,077,074	RGD:6480464	CTD
G	Gsk3b	glycogen synthase kinase 3 beta		multiple interactions	ISO	11	64,284,731	64,428,698	RGD:6480464	CTD
G	Gsk3b	glycogen synthase kinase 3 beta		increases expression	ISO	11	64,284,731	64,428,698	RGD:6480464	CTD
G	Gstm2	glutathione S-transferase mu 2		multiple interactions	ISO	2	203,549,022	203,553,380	RGD:6480464	CTD
G	Gsto1	glutathione S-transferase omega 1		multiple interactions	ISO	1	253,228,547	253,238,531	RGD:6480464	CTD
G	Gstp1	glutathione S-transferase pi 1		multiple interactions	ISO	1	206,627,398	206,629,866	RGD:6480464	CTD
G	Hprt1	hypoxanthine phosphoribosyltransferase 1		multiple interactions	ISO	X	139,929,647	139,961,616	RGD:6480464	CTD
G	Hspb1	heat shock protein 1		decreases expression	ISO	12	21,911,223	21,912,784	RGD:6480464	CTD
G	Hspb1	heat shock protein 1		multiple interactions	ISO	12	21,911,223	21,912,784	RGD:6480464	CTD
G	Hspb1	heat shock protein 1		affects expression	ISO	12	21,911,223	21,912,784	RGD:6480464	CTD
G	Hspb1	heat shock protein 1		increases expression	ISO	12	21,911,223	21,912,784	RGD:6480464	CTD
G	Ier3	immediate early response 3		multiple interactions	ISO	20	3,076,568	3,077,772	RGD:6480464	CTD
G	Igf1	insulin-like growth factor 1		multiple interactions	ISO	7	24,531,669	24,605,742	RGD:6480464	CTD
G	Il1b	interleukin 1 beta		multiple interactions	ISO	3	116,964,422	116,970,867	RGD:6480464	CTD
G	Il1rl1	interleukin 1 receptor-like 1		increases expression	ISO	9	39,577,879	39,624,781	RGD:6480464	CTD
G	Irak1	interleukin-1 receptor-associated kinase 1		multiple interactions	ISO	X	159,960,184	159,969,180	RGD:6480464	CTD
G	Jak2	Janus kinase 2		multiple interactions	ISO	1	232,915,995	232,974,763	RGD:6480464	CTD
G	Jun	jun proto-oncogene		multiple interactions	ISO	5	115,358,166	115,361,259	RGD:6480464	CTD
G	Jun	jun proto-oncogene		increases expression	ISO	5	115,358,166	115,361,259	RGD:6480464	CTD
G	Junb	jun B proto-oncogene		increases expression	ISO	19	24,831,536	24,833,320	RGD:6480464	CTD
G	Lox	lysyl oxidase		multiple interactions	ISO	18	47,896,674	47,970,829	RGD:6480464	CTD
G	Lpl	lipoprotein lipase		multiple interactions	ISO	16	22,533,105	22,556,905	RGD:6480464	CTD
G	Map3k12	mitogen activated protein kinase kinase kinase 12		multiple interactions	ISO	7	141,254,451	141,264,979	RGD:6480464	CTD
G	Mapk1	mitogen activated protein kinase 1		increases activity	EXP	11	85,968,732	86,030,387	RGD:6480464	CTD
G	Mapk1	mitogen activated protein kinase 1		increases activity	ISO	11	85,968,732	86,030,387	RGD:6480464	CTD
G	Mapk1	mitogen activated protein kinase 1		increases activity	ISO	11	85,968,732	86,030,387	RGD:6480464	CTD
G	Mapk1	mitogen activated protein kinase 1		increases phosphorylation	EXP	11	85,968,732	86,030,387	RGD:6480464	CTD
G	Mapk3	mitogen activated protein kinase 3		increases activity	ISO	1	185,935,044	185,941,245	RGD:6480464	CTD
G	Mapk3	mitogen activated protein kinase 3		increases activity	ISO	1	185,935,044	185,941,245	RGD:6480464	CTD
G	Mapk3	mitogen activated protein kinase 3		increases phosphorylation	EXP	1	185,935,044	185,941,245	RGD:6480464	CTD
G	Mapk7	mitogen-activated protein kinase 7		multiple interactions	ISO	10	47,649,203	47,654,316	RGD:6480464	CTD
G	Mapk7	mitogen-activated protein kinase 7		multiple interactions	ISO	10	47,649,203	47,654,316	RGD:6480464	CTD
G	Mapt	microtubule-associated protein tau		multiple interactions	ISO	10	93,411,098	93,508,762	RGD:6480464	CTD
G	Mapt	microtubule-associated protein tau		multiple interactions	ISO	10	93,411,098	93,508,762	RGD:6480464	CTD
G	Mapt	microtubule-associated protein tau		increases phosphorylation	ISO	10	93,411,098	93,508,762	RGD:6480464	CTD
G	Mapt	microtubule-associated protein tau		multiple interactions	ISO	10	93,411,098	93,508,762	RGD:6480464	CTD
G	Mapt	microtubule-associated protein tau		multiple interactions	EXP	10	93,411,098	93,508,762	RGD:6480464	CTD
G	Mapt	microtubule-associated protein tau		multiple interactions	EXP	10	93,411,098	93,508,762	RGD:6480464	CTD
G	Mapt	microtubule-associated protein tau		increases phosphorylation	EXP	10	93,411,098	93,508,762	RGD:6480464	CTD
G	Mapt	microtubule-associated protein tau		increases phosphorylation	ISO	10	93,411,098	93,508,762	RGD:6480464	CTD
G	Mapt	microtubule-associated protein tau		affects phosphorylation	ISO	10	93,411,098	93,508,762	RGD:6480464	CTD
G	Marcks	myristoylated alanine rich protein kinase C substrate		multiple interactions	ISO	20	41,304,058	41,310,104	RGD:6480464	CTD
G	Med1	mediator complex subunit 1		multiple interactions	ISO	10	86,917,525	86,959,080	RGD:6480464	CTD
G	Mesdc2	mesoderm development candidate 2		decreases expression	ISO	1	140,167,851	140,173,514	RGD:6480464	CTD
G	Mgst3	microsomal glutathione S-transferase 3		multiple interactions	ISO	13	83,038,049	83,058,802	RGD:6480464	CTD
G	Mmp2	matrix metallopeptidase 2		multiple interactions	ISO	19	15,246,036	15,275,061	RGD:6480464	CTD
G	Mt1a	metallothionein 1a		multiple interactions	ISO	19	11,261,631	11,262,647	RGD:6480464	CTD
G	Myh7	myosin, heavy chain 7, cardiac muscle, beta		multiple interactions	ISO	15	33,072,928	33,094,595	RGD:6480464	CTD
G	Nans	N-acetylneuraminic acid synthase		decreases expression	ISO	5	63,072,673	63,090,183	RGD:6480464	CTD
G	Ncor1	nuclear receptor co-repressor 1		decreases activity	ISO	10	48,481,110	48,628,538	RGD:6480464	CTD
G	Ncor1	nuclear receptor co-repressor 1		multiple interactions	ISO	10	48,481,110	48,628,538	RGD:6480464	CTD
G	Ncor2	nuclear receptor co-repressor 2		affects localization	EXP	12	32,617,643	32,725,753	RGD:6480464	CTD
G	Nfe2l2	nuclear factor, erythroid derived 2, like 2		increases expression	ISO	3	58,366,693	58,394,116	RGD:6480464	CTD
G	Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1		multiple interactions	ISO	2	233,091,013	233,187,501	RGD:6480464	CTD
G	Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1		multiple interactions	ISO	2	233,091,013	233,187,501	RGD:6480464	CTD
G	Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1		multiple interactions	ISO	2	233,091,013	233,187,501	RGD:6480464	CTD
G	Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1		multiple interactions	ISO	2	233,091,013	233,187,501	RGD:6480464	CTD
G	Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1		multiple interactions	ISO	2	233,091,013	233,187,501	RGD:6480464	CTD
G	Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1		multiple interactions	ISO	2	233,091,013	233,187,501	RGD:6480464	CTD
G	Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1		multiple interactions	ISO	2	233,091,013	233,187,501	RGD:6480464	CTD
G	Nme1	NME/NM23 nucleoside diphosphate kinase 1		multiple interactions	ISO	10	82,591,705	82,601,075	RGD:6480464	CTD
G	Nme1	NME/NM23 nucleoside diphosphate kinase 1		decreases expression	ISO	10	82,591,705	82,601,075	RGD:6480464	CTD
G	Nr1i2	nuclear receptor subfamily 1, group I, member 2		increases activity	ISO	11	64,239,918	64,276,702	RGD:6480464	CTD
G	Nr3c1	nuclear receptor subfamily 3, group C, member 1		decreases expression	ISO	18	32,371,496	32,459,145	RGD:6480464	CTD
G	Nup54	nucleoporin 54		increases expression	ISO	14	17,178,761	17,197,062	RGD:6480464	CTD
G	Orm1	orosomucoid 1		increases expression	ISO	5	80,325,042	80,328,194	RGD:6480464	CTD
G	Parp1	poly (ADP-ribose) polymerase 1		multiple interactions	ISO	13	96,309,670	96,341,486	RGD:6480464	CTD
G	Pcbp2	poly(rC) binding protein 2		multiple interactions	ISO	7	141,232,766	141,253,910	RGD:6480464	CTD
G	Pcmt1	protein-L-isoaspartate (D-aspartate) O-methyltransferase 1		decreases expression	ISO	1	2,287,981	2,304,638	RGD:6480464	CTD
G	Pcna	proliferating cell nuclear antigen		multiple interactions	ISO	3	120,008,715	120,012,589	RGD:6480464	CTD
G	Pdgfra	platelet derived growth factor receptor, alpha polypeptide		multiple interactions	ISO	14	35,369,422	35,418,126	RGD:6480464	CTD
G	Pdia3	protein disulfide isomerase family A, member 3		multiple interactions	ISO	3	108,216,414	108,240,138	RGD:6480464	CTD
G	Pdx1	pancreatic and duodenal homeobox 1		multiple interactions	ISO				RGD:6480464	CTD
G	Pdx1	pancreatic and duodenal homeobox 1		multiple interactions	ISO				RGD:6480464	CTD
G	Pgam1	phosphoglycerate mutase 1 (brain)		multiple interactions	ISO				RGD:6480464	CTD
G	Pgr	progesterone receptor		decreases expression	ISO	8	5,784,717	5,845,901	RGD:6480464	CTD
G	Pik3r5	phosphoinositide-3-kinase, regulatory subunit 5		increases expression	ISO	10	55,227,872	55,248,301	RGD:6480464	CTD
G	Podxl	podocalyxin-like		multiple interactions	ISO	4	58,611,904	58,658,598	RGD:6480464	CTD
G	Ppara	peroxisome proliferator activated receptor alpha		multiple interactions	ISO	7	123,729,774	123,807,090	RGD:6480464	CTD
G	Ppara	peroxisome proliferator activated receptor alpha		multiple interactions	ISO	7	123,729,774	123,807,090	RGD:6480464	CTD
G	Ppara	peroxisome proliferator activated receptor alpha		multiple interactions	EXP	7	123,729,774	123,807,090	RGD:6480464	CTD
G	Ppara	peroxisome proliferator activated receptor alpha		increases phosphorylation	EXP	7	123,729,774	123,807,090	RGD:6480464	CTD
G	Ppia	peptidylprolyl isomerase A (cyclophilin A)		decreases expression	ISO	14	87,165,998	87,169,995	RGD:6480464	CTD
G	Ppp1ca	protein phosphatase 1, catalytic subunit, alpha isozyme		multiple interactions	ISO	1	206,774,719	206,778,336	RGD:6480464	CTD
G	Ppp1ca	protein phosphatase 1, catalytic subunit, alpha isozyme		decreases activity	EXP	1	206,774,719	206,778,336	RGD:6480464	CTD
G	Ppp2ca	protein phosphatase 2, catalytic subunit, alpha isozyme		multiple interactions	ISO	10	37,621,256	37,641,008	RGD:6480464	CTD
G	Ppp2ca	protein phosphatase 2, catalytic subunit, alpha isozyme		decreases activity	ISO	10	37,621,256	37,641,008	RGD:6480464	CTD
G	Ppp2ca	protein phosphatase 2, catalytic subunit, alpha isozyme		decreases activity	ISO	10	37,621,256	37,641,008	RGD:6480464	CTD
G	Ppp2ca	protein phosphatase 2, catalytic subunit, alpha isozyme		multiple interactions	ISO	10	37,621,256	37,641,008	RGD:6480464	CTD
G	Ppp2r1a	protein phosphatase 2, regulatory subunit A, alpha		increases expression	ISO	1	58,442,220	58,461,462	RGD:6480464	CTD
G	Prdx5	peroxiredoxin 5		multiple interactions	ISO	1	209,583,414	209,586,399	RGD:6480464	CTD
G	Prdx5	peroxiredoxin 5		decreases expression	ISO	1	209,583,414	209,586,399	RGD:6480464	CTD
G	Prdx6	peroxiredoxin 6		multiple interactions	ISO	13	76,824,968	76,835,517	RGD:6480464	CTD
G	Ptgs2	prostaglandin-endoperoxide synthase 2		increases expression	ISO	13	64,427,288	64,432,978	RGD:6480464	CTD
G	Ptgs2	prostaglandin-endoperoxide synthase 2		increases expression	ISO	13	64,427,288	64,432,978	RGD:6480464	CTD
G	Ptn	pleiotrophin		multiple interactions	ISO	4	64,078,755	64,160,135	RGD:6480464	CTD
G	Pttg1	pituitary tumor-transforming 1		multiple interactions	ISO	10	28,527,409	28,532,831	RGD:6480464	CTD
G	Racgap1	Rac GTPase-activating protein 1		multiple interactions	ISO	7	138,366,356	138,395,716	RGD:6480464	CTD
G	Rad21	RAD21 homolog (S. pombe)		multiple interactions	ISO	7	88,267,648	88,294,703	RGD:6480464	CTD
G	Raf1	v-raf-leukemia viral oncogene 1		multiple interactions	ISO	4	151,752,583	151,775,609	RGD:6480464	CTD
G	Rara	retinoic acid receptor, alpha		multiple interactions	EXP	10	87,740,479	87,753,265	RGD:6480464	CTD
G	Rb1	retinoblastoma 1		multiple interactions	ISO	15	53,828,881	53,962,099	RGD:6480464	CTD
G	Rbl1	retinoblastoma-like 1 (p107)		multiple interactions	ISO	3	147,734,622	147,796,630	RGD:6480464	CTD
G	Rbl2	retinoblastoma-like 2		multiple interactions	ISO	19	17,045,131	17,092,597	RGD:6480464	CTD
G	Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)		multiple interactions	ISO	1	208,262,669	208,273,148	RGD:6480464	CTD
G	Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)		multiple interactions	ISO	1	208,262,669	208,273,148	RGD:6480464	CTD
G	Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)		multiple interactions	ISO	1	208,262,669	208,273,148	RGD:6480464	CTD
G	Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)		multiple interactions	ISO	1	208,262,669	208,273,148	RGD:6480464	CTD
G	Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)		multiple interactions	ISO	1	208,262,669	208,273,148	RGD:6480464	CTD
G	Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)		multiple interactions	ISO	1	208,262,669	208,273,148	RGD:6480464	CTD
G	Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)		increases phosphorylation	ISO	1	208,262,669	208,273,148	RGD:6480464	CTD
G	Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)		multiple interactions	ISO	1	208,262,669	208,273,148	RGD:6480464	CTD
G	Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)		multiple interactions	ISO	1	208,262,669	208,273,148	RGD:6480464	CTD
G	Rpl7	ribosomal protein L7		multiple interactions	ISO	5	2,315,766	2,318,774	RGD:6480464	CTD
G	Rps12	ribosomal protein S12		decreases expression	ISO	1	22,265,326	22,267,482	RGD:6480464	CTD
G	Rps20	ribosomal protein S20		multiple interactions	ISO	5	17,119,797	17,120,959	RGD:6480464	CTD
G	Rxra	retinoid X receptor alpha		multiple interactions	ISO	3	6,605,782	6,689,224	RGD:6480464	CTD
G	Scarb1	scavenger receptor class B, member 1		increases expression	ISO	12	32,390,183	32,457,661	RGD:6480464	CTD
G	Semg1	semenogelin I		decreases expression	ISO	3	155,179,283	155,182,131	RGD:6480464	CTD
G	Sepp1	selenoprotein P, plasma, 1		multiple interactions	ISO	2	52,451,883	52,462,263	RGD:6480464	CTD
G	Slc19a1	solute carrier family 19 (folate transporter), member 1		multiple interactions	EXP	20	11,984,283	12,001,865	RGD:6480464	CTD
G	Slc19a1	solute carrier family 19 (folate transporter), member 1		decreases activity	EXP	20	11,984,283	12,001,865	RGD:6480464	CTD
G	Slc2a1	solute carrier family 2 (facilitated glucose transporter), member 1		increases expression	ISO	5	139,690,801	139,719,021	RGD:6480464	CTD
G	Sod1	superoxide dismutase 1, soluble		decreases expression	ISO	11	29,810,766	29,816,342	RGD:6480464	CTD
G	Sod2	superoxide dismutase 2, mitochondrial		multiple interactions	ISO	1	41,862,997	41,870,327	RGD:6480464	CTD
G	Spp1	secreted phosphoprotein 1		multiple interactions	ISO				RGD:6480464	CTD
G	Sqle	squalene epoxidase		multiple interactions	ISO	7	96,096,897	96,111,772	RGD:6480464	CTD
G	Stmn1	stathmin 1		increases expression	ISO	5	153,226,420	153,232,084	RGD:6480464	CTD
G	Syn1	synapsin I		multiple interactions	ISO	X	12,512,241	12,556,160	RGD:6480464	CTD
G	Tf	transferrin		decreases uptake	ISO	8	108,217,774	108,244,487	RGD:6480464	CTD
G	Tfrc	transferrin receptor		increases expression	ISO	11	69,976,258	69,998,098	RGD:6480464	CTD
G	Thbs1	thrombospondin 1		multiple interactions	ISO				RGD:6480464	CTD
G	Thbs2	thrombospondin 2		multiple interactions	ISO	1	53,584,406	53,613,652	RGD:6480464	CTD
G	Timp2	TIMP metallopeptidase inhibitor 2		multiple interactions	ISO	10	108,310,473	108,358,821	RGD:6480464	CTD
G	Tmsb4x	thymosin beta 4, X-linked		multiple interactions	ISO				RGD:6480464	CTD
G	Tnf	tumor necrosis factor		multiple interactions	ISO	20	3,661,000	3,663,618	RGD:6480464	CTD
G	Tnf	tumor necrosis factor		increases expression	ISO	20	3,661,000	3,663,618	RGD:6480464	CTD
G	Tnf	tumor necrosis factor		increases expression	ISO	20	3,661,000	3,663,618	RGD:6480464	CTD
G	Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10		multiple interactions	ISO	2	113,204,303	113,221,550	RGD:6480464	CTD
G	Top2a	topoisomerase (DNA) II alpha		multiple interactions	ISO	10	87,771,337	87,800,960	RGD:6480464	CTD
G	Tp53	tumor protein p53		affects localization	ISO	10	56,399,721	56,411,150	RGD:6480464	CTD
G	Tp53	tumor protein p53		decreases expression	ISO	10	56,399,721	56,411,150	RGD:6480464	CTD
G	Ttc3	tetratricopeptide repeat domain 3		multiple interactions	ISO	11	34,617,072	34,659,043	RGD:6480464	CTD
G	Txn1	thioredoxin 1		decreases expression	ISO	5	75,921,365	75,933,595	RGD:6480464	CTD
G	Txn1	thioredoxin 1		multiple interactions	ISO	5	75,921,365	75,933,595	RGD:6480464	CTD
G	Ubc	ubiquitin C		multiple interactions	ISO	12	32,333,211	32,337,944	RGD:6480464	CTD
G	Ucp2	uncoupling protein 2 (mitochondrial, proton carrier)		multiple interactions	ISO	1	157,925,514	157,928,222	RGD:6480464	CTD
G	Vdr	vitamin D (1,25- dihydroxyvitamin D3) receptor		multiple interactions	ISO	7	136,567,614	136,617,280	RGD:6480464	CTD
G	Vegfa	vascular endothelial growth factor A		increases expression	ISO	9	10,520,730	10,536,071	RGD:6480464	CTD
G	Zeb2	zinc finger E-box binding homeobox 2		increases expression	ISO	3	25,513,009	25,654,964	RGD:6480464	CTD

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	492574
role	482262
chemical role	208077
inhibitor	73170
enzyme inhibitor	68950
protein serine/threonine phosphatase inhibitor	227
okadaic acid	227
Path 2
Term	Annotations
CHEBI ontology	492574
subatomic particle	491537
composite particle	491537
hadron	491537
baryon	491537
nucleon	491537
atomic nucleus	491537
atom	491537
main group element atom	461203
p-block element atom	458699
carbon group element atom	410677
carbon atom	407233
organic molecular entity	407226
heteroorganic entity	324767
organochalcogen compound	226950
organooxygen compound	213735
ether	7016
cyclic ether	1919
polycyclic ether	1060
okadaic acid	227