ONTOLOGY REPORT - ANNOTATIONS

Term:daunorubicin
go back to main search page
Accession:CHEBI:41977 term browser browse the term
Definition:A natural product found in Actinomadura roseola.
Synonyms:exact_synonym: (1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside
 related_synonym: (8S-cis)-8-acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-napthacenedione;   C27H29NO10;   COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(C)=O;   Daunomycin;   InChI=1S/C27H29NO10/c1-10-22(30)14(28)7-17(37-10)38-16-9-27(35,11(2)29)8-13-19(16)26(34)21-20(24(13)32)23(31)12-5-4-6-15(36-3)18(12)25(21)33/h4-6,10,14,16-17,22,30,32,34-35H,7-9,28H2,1-3H3/t10-,14-,16-,17-,22+,27-/m0/s1;   InChIKey=STQGQHZAVUOBTE-VGBVRHCVSA-N;   acetyladriamycin;   daunorubicinum;   leukaemomycin C
 alt_id: CHEBI:23560;   CHEBI:41970;   CHEBI:4330;   CHEBI:65723
 xref_casrn: 20830-81-3
 xref: ChEMBL:436913 "ChEMBL COMPOUND";   ChemIDplus:1445583 "Beilstein Registry Number";   ChemIDplus:20830-81-3 "CAS Registry Number";   DrugBank:DB00694 "DrugBank";   KEGG COMPOUND:20830-81-3 "CAS Registry Number";   KEGG COMPOUND:C01907 "KEGG COMPOUND";   LIPID MAPS:LMPK13050002 "LIPID MAPS instance"
 xref_mesh: MESH:D003630
 xref: PDBeChem:DM1 "PDBeChem";   Wikipedia:Daunorubicin "Wikipedia"
 cyclic_relationship: is_conjugate_base_of CHEBI:64677

  • Rat
  • Mouse
  • Human
  • All
  • show annotations for term's descendants
  •     Sort by:
daunorubicin term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link affects response to substance ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link multiple interactions ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link increases response to substance ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link decreases uptake ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link increases transport ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link increases export ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link multiple interactions ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link multiple interactions ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link multiple interactions ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link decreases expression ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link multiple interactions ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link affects transport EXP 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link multiple interactions EXP 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link multiple interactions ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link multiple interactions ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link increases transport ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 GBrowse link affects response to substance ISO 10 452,239 575,705 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 GBrowse link affects export ISO 10 452,239 575,705 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 GBrowse link decreases response to substance ISO 10 452,239 575,705 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 GBrowse link increases secretion ISO 10 452,239 575,705 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 GBrowse link affects response to substance ISO 10 452,239 575,705 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 GBrowse link multiple interactions ISO 10 452,239 575,705 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 GBrowse link decreases response to substance ISO 10 452,239 575,705 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 GBrowse link multiple interactions ISO 10 452,239 575,705 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 GBrowse link multiple interactions ISO 10 452,239 575,705 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 GBrowse link multiple interactions ISO 10 452,239 575,705 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 GBrowse link multiple interactions ISO 10 452,239 575,705 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 GBrowse link decreases uptake ISO 10 452,239 575,705 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 GBrowse link affects response to substance ISO 10 452,239 575,705 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 GBrowse link affects response to substance ISO 10 452,239 575,705 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 GBrowse link increases secretion ISO 10 452,239 575,705 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 GBrowse link decreases response to substance ISO 10 452,239 575,705 RGD:6480464 CTD
G Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 affects response to substance ISO RGD:6480464 CTD
G Abcg2 ATP-binding cassette, subfamily G (WHITE), member 2 GBrowse link multiple interactions ISO 4 87,502,584 87,560,017 RGD:6480464 CTD
G Abcg2 ATP-binding cassette, subfamily G (WHITE), member 2 GBrowse link increases expression ISO 4 87,502,584 87,560,017 RGD:6480464 CTD
G Abl1 c-abl oncogene 1, non-receptor tyrosine kinase GBrowse link decreases response to substance ISO 3 10,804,594 10,907,162 RGD:6480464 CTD
G Agrn agrin GBrowse link increases expression ISO 5 172,999,420 173,020,764 RGD:6480464 CTD
G Agtr1a angiotensin II receptor, type 1a GBrowse link increases expression EXP 17 40,629,318 40,684,982 RGD:6480464 CTD
G Agtr1a angiotensin II receptor, type 1a GBrowse link multiple interactions EXP 17 40,629,318 40,684,982 RGD:6480464 CTD
G Akr1a1 aldo-keto reductase family 1, member A1 (aldehyde reductase) GBrowse link increases reduction ISO 5 136,920,561 136,937,422 RGD:6480464 CTD
G Akr1a1 aldo-keto reductase family 1, member A1 (aldehyde reductase) GBrowse link increases metabolic processing ISO 5 136,920,561 136,937,422 RGD:6480464 CTD
G Akr1a1 aldo-keto reductase family 1, member A1 (aldehyde reductase) GBrowse link multiple interactions ISO 5 136,920,561 136,937,422 RGD:6480464 CTD
G Akr1a1 aldo-keto reductase family 1, member A1 (aldehyde reductase) GBrowse link affects metabolic processing ISO 5 136,920,561 136,937,422 RGD:6480464 CTD
G Akr1b1 aldo-keto reductase family 1, member B1 (aldose reductase) GBrowse link increases reduction ISO 4 61,645,438 61,659,530 RGD:6480464 CTD
G Akr1b10 aldo-keto reductase family 1, member B10 (aldose reductase) GBrowse link decreases response to substance ISO 4 61,755,871 61,771,264 RGD:6480464 CTD
G Akr1b10 aldo-keto reductase family 1, member B10 (aldose reductase) GBrowse link multiple interactions ISO 4 61,755,871 61,771,264 RGD:6480464 CTD
G Akr1b10 aldo-keto reductase family 1, member B10 (aldose reductase) GBrowse link increases reduction ISO 4 61,755,871 61,771,264 RGD:6480464 CTD
G Akr1c3 aldo-keto reductase family 1, member C3 GBrowse link increases metabolic processing ISO 17 77,269,626 77,286,521 RGD:6480464 CTD
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link decreases response to substance ISO 6 137,640,482 137,657,552 RGD:6480464 CTD
G Angpt1 angiopoietin 1 GBrowse link decreases expression EXP 7 78,195,504 78,451,471 RGD:6480464 CTD
G Angpt2 angiopoietin 2 GBrowse link increases expression EXP 16 75,891,757 75,942,255 RGD:6480464 CTD
G Ankrd1 ankyrin repeat domain 1 GBrowse link decreases expression EXP 1 240,316,123 240,324,804 RGD:6480464 CTD
G Ano3 anoctamin 3 GBrowse link affects response to substance ISO 3 96,123,925 96,237,157 RGD:6480464 CTD
G Anxa2 annexin A2 GBrowse link decreases expression ISO 8 73,897,618 73,934,041 RGD:6480464 CTD
G Anxa4 annexin A4 GBrowse link increases expression ISO 4 120,889,617 120,947,662 RGD:6480464 CTD
G Apex1 APEX nuclease (multifunctional DNA repair enzyme) 1 GBrowse link multiple interactions ISO 15 26,904,124 26,906,224 RGD:6480464 CTD
G Apob apolipoprotein B GBrowse link increases expression EXP 6 31,508,060 31,548,083 RGD:6480464 CTD
G Apoc3 apolipoprotein C-III increases expression EXP RGD:6480464 CTD
G Atm ataxia telangiectasia mutated GBrowse link increases expression ISO 8 56,894,746 56,996,565 RGD:6480464 CTD
G Bard1 BRCA1 associated RING domain 1 GBrowse link affects expression ISO 9 70,120,151 70,198,591 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link multiple interactions ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link multiple interactions ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link multiple interactions ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link multiple interactions ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link decreases response to substance ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link multiple interactions ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link multiple interactions ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link decreases expression ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link multiple interactions ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bid BH3 interacting domain death agonist GBrowse link multiple interactions ISO 4 157,296,383 157,318,481 RGD:6480464 CTD
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO RGD:6480464 CTD
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO RGD:6480464 CTD
G Cab39 calcium binding protein 39 GBrowse link decreases expression ISO 9 84,528,678 84,590,375 RGD:6480464 CTD
G Cacna1s calcium channel, voltage-dependent, L type, alpha 1S subunit affects response to substance ISO RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp8 caspase 8 GBrowse link multiple interactions ISO 9 57,389,353 57,437,803 RGD:6480464 CTD
G Cat catalase GBrowse link affects response to substance ISO 3 88,654,077 88,686,212 RGD:6480464 CTD
G Cbr1 carbonyl reductase 1 GBrowse link increases metabolic processing ISO 11 33,787,957 33,790,320 RGD:6480464 CTD
G Cbr1 carbonyl reductase 1 GBrowse link multiple interactions ISO 11 33,787,957 33,790,320 RGD:6480464 CTD
G Cbr1 carbonyl reductase 1 GBrowse link decreases metabolic processing ISO 11 33,787,957 33,790,320 RGD:6480464 CTD
G Cbr1 carbonyl reductase 1 GBrowse link increases reduction ISO 11 33,787,957 33,790,320 RGD:6480464 CTD
G Cbr3 carbonyl reductase 3 GBrowse link affects response to substance ISO 11 33,913,961 33,922,221 RGD:6480464 CTD
G Cbr3 carbonyl reductase 3 GBrowse link affects metabolic processing ISO 11 33,913,961 33,922,221 RGD:6480464 CTD
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link decreases expression ISO 10 70,256,263 70,258,061 RGD:6480464 CTD
G Ccl4 chemokine (C-C motif) ligand 4 GBrowse link decreases expression ISO 10 71,759,643 71,761,115 RGD:6480464 CTD
G Ccnd3 cyclin D3 increases expression ISO RGD:6480464 CTD
G Ccne1 cyclin E1 GBrowse link affects expression ISO 1 90,568,189 90,577,426 RGD:6480464 CTD
G Ccng2 cyclin G2 GBrowse link increases expression ISO 14 16,338,132 16,346,628 RGD:6480464 CTD
G Cdc25a cell division cycle 25A GBrowse link increases expression ISO 8 114,237,704 114,255,971 RGD:6480464 CTD
G Cdh13 cadherin 13 GBrowse link affects response to substance ISO 19 48,507,173 49,575,123 RGD:6480464 CTD
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link increases expression ISO 20 7,376,325 7,386,778 RGD:6480464 CTD
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link increases expression ISO 20 7,376,325 7,386,778 RGD:6480464 CTD
G Cdkn1b cyclin-dependent kinase inhibitor 1B GBrowse link multiple interactions EXP 4 171,841,705 171,846,506 RGD:6480464 CTD
G Cdkn1b cyclin-dependent kinase inhibitor 1B GBrowse link affects expression EXP 4 171,841,705 171,846,506 RGD:6480464 CTD
G Cdkn2a cyclin-dependent kinase inhibitor 2A GBrowse link affects expression ISO 5 108,908,749 108,916,380 RGD:6480464 CTD
G Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) GBrowse link increases expression ISO 5 108,939,669 108,945,293 RGD:6480464 CTD
G Ceacam1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) GBrowse link increases expression ISO 1 80,742,540 80,758,943 RGD:6480464 CTD
G Cebpz CCAAT/enhancer binding protein zeta GBrowse link decreases expression ISO 6 1,698,162 1,715,846 RGD:6480464 CTD
G Clk2 CDC-like kinase 2 GBrowse link increases expression ISO 2 181,244,665 181,257,364 RGD:6480464 CTD
G Clybl citrate lyase beta like GBrowse link affects response to substance ISO 15 107,313,924 107,539,458 RGD:6480464 CTD
G Cmc2 COX assembly mitochondrial protein 2 GBrowse link affects response to substance ISO 19 47,002,952 47,028,957 RGD:6480464 CTD
G Cmip c-Maf-inducing protein GBrowse link affects response to substance ISO 19 47,364,495 47,572,096 RGD:6480464 CTD
G Cwc27 CWC27 spliceosome-associated protein homolog (S. cerevisiae) GBrowse link affects response to substance ISO 2 35,567,205 35,825,390 RGD:6480464 CTD
G Cyba cytochrome b-245, alpha polypeptide GBrowse link multiple interactions EXP 19 52,713,150 52,721,609 RGD:6480464 CTD
G Cyba cytochrome b-245, alpha polypeptide GBrowse link increases expression EXP 19 52,713,150 52,721,609 RGD:6480464 CTD
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 GBrowse link affects response to substance ISO 6 2,548,224 2,553,767 RGD:6480464 CTD
G Dffa DNA fragmentation factor, alpha subunit GBrowse link increases degradation ISO 5 166,179,130 166,192,029 RGD:6480464 CTD
G E2f5 E2F transcription factor 5 GBrowse link increases expression ISO 2 88,346,236 88,361,733 RGD:6480464 CTD
G Edn1 endothelin 1 GBrowse link increases expression EXP 17 28,303,886 28,309,775 RGD:6480464 CTD
G Edn1 endothelin 1 GBrowse link multiple interactions EXP 17 28,303,886 28,309,775 RGD:6480464 CTD
G Ednra endothelin receptor type A GBrowse link increases expression EXP 19 32,042,366 32,108,153 RGD:6480464 CTD
G Ednra endothelin receptor type A GBrowse link multiple interactions EXP 19 32,042,366 32,108,153 RGD:6480464 CTD
G Ednrb endothelin receptor type B GBrowse link increases expression EXP 15 87,893,141 87,898,700 RGD:6480464 CTD
G Ednrb endothelin receptor type B GBrowse link multiple interactions EXP 15 87,893,141 87,898,700 RGD:6480464 CTD
G Egf epidermal growth factor GBrowse link multiple interactions ISO 2 227,103,900 227,195,062 RGD:6480464 CTD
G Ei24 etoposide induced 2.4 GBrowse link increases expression ISO 8 38,028,043 38,044,316 RGD:6480464 CTD
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 GBrowse link increases phosphorylation ISO 16 69,110,522 69,123,895 RGD:6480464 CTD
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 GBrowse link multiple interactions ISO 16 69,110,522 69,123,895 RGD:6480464 CTD
G Epm2aip1 EPM2A (laforin) interacting protein 1 GBrowse link increases expression ISO 8 115,653,794 115,656,867 RGD:6480464 CTD
G Faslg Fas ligand (TNF superfamily, member 6) GBrowse link multiple interactions EXP 13 77,472,950 77,480,210 RGD:6480464 CTD
G Faslg Fas ligand (TNF superfamily, member 6) GBrowse link increases expression EXP 13 77,472,950 77,480,210 RGD:6480464 CTD
G Fdxr ferredoxin reductase GBrowse link increases expression ISO 10 105,342,684 105,351,374 RGD:6480464 CTD
G Gapt Grb2-binding adaptor protein, transmembrane GBrowse link affects response to substance ISO 2 41,759,021 41,761,323 RGD:6480464 CTD
G Gpc5 glypican 5 GBrowse link affects response to substance ISO 15 99,917,274 101,353,034 RGD:6480464 CTD
G Gstm1 glutathione S-transferase mu 1 GBrowse link affects response to substance ISO 2 203,575,444 203,580,821 RGD:6480464 CTD
G Hnrpd heterogeneous nuclear ribonucleoprotein D GBrowse link affects response to substance ISO 14 10,917,674 10,935,989 RGD:6480464 CTD
G Icam1 intercellular adhesion molecule 1 GBrowse link increases expression EXP 8 20,040,177 20,051,939 RGD:6480464 CTD
G Icam1 intercellular adhesion molecule 1 GBrowse link multiple interactions EXP 8 20,040,177 20,051,939 RGD:6480464 CTD
G Ikbke inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon GBrowse link affects response to substance ISO 13 44,197,625 44,222,609 RGD:6480464 CTD
G Il6r interleukin 6 receptor GBrowse link decreases expression ISO 2 182,078,049 182,128,135 RGD:6480464 CTD
G Ilkap integrin-linked kinase-associated serine/threonine phosphatase GBrowse link affects response to substance ISO 9 90,602,949 90,626,753 RGD:6480464 CTD
G Inpp4b inositol polyphosphate-4-phosphatase, type II GBrowse link affects response to substance ISO 19 27,722,430 28,363,639 RGD:6480464 CTD
G Krt19 keratin 19 GBrowse link increases expression EXP 10 89,080,953 89,085,670 RGD:6480464 CTD
G Krt8 keratin 8 GBrowse link increases expression EXP 7 140,713,902 140,721,199 RGD:6480464 CTD
G LOC499643 similar to hypothetical protein FLJ25371 GBrowse link affects response to substance ISO 2 170,755,542 170,870,813 RGD:6480464 CTD
G Lsamp limbic system-associated membrane protein GBrowse link affects response to substance ISO 11 60,170,406 60,870,875 RGD:6480464 CTD
G Map1b microtubule-associated protein 1B GBrowse link affects response to substance ISO 2 30,415,235 30,508,354 RGD:6480464 CTD
G Map2k3 mitogen activated protein kinase kinase 3 GBrowse link increases expression ISO 10 47,075,270 47,096,617 RGD:6480464 CTD
G Map3k5 mitogen-activated protein kinase kinase kinase 5 GBrowse link decreases expression ISO 1 15,205,361 15,346,422 RGD:6480464 CTD
G Mapt microtubule-associated protein tau GBrowse link decreases expression ISO 10 93,411,098 93,508,762 RGD:6480464 CTD
G Mdm4 Mdm4 p53 binding protein homolog (mouse) GBrowse link decreases expression ISO 13 45,895,832 45,931,421 RGD:6480464 CTD
G Mt1a metallothionein 1a GBrowse link increases expression EXP 19 11,261,631 11,262,647 RGD:6480464 CTD
G Mt1a metallothionein 1a GBrowse link multiple interactions EXP 19 11,261,631 11,262,647 RGD:6480464 CTD
G Mtor mechanistic target of rapamycin (serine/threonine kinase) GBrowse link increases phosphorylation ISO 5 165,531,402 165,640,899 RGD:6480464 CTD
G Mtor mechanistic target of rapamycin (serine/threonine kinase) GBrowse link multiple interactions ISO 5 165,531,402 165,640,899 RGD:6480464 CTD
G Ncf2 neutrophil cytosolic factor 2 GBrowse link increases expression EXP 13 67,806,516 67,834,105 RGD:6480464 CTD
G Ncf2 neutrophil cytosolic factor 2 GBrowse link multiple interactions EXP 13 67,806,516 67,834,105 RGD:6480464 CTD
G Nck2 NCK adaptor protein 2 GBrowse link decreases expression ISO 9 42,650,261 42,776,967 RGD:6480464 CTD
G Ngef neuronal guanine nucleotide exchange factor GBrowse link affects response to substance ISO 9 86,294,206 86,327,765 RGD:6480464 CTD
G Nox4 NADPH oxidase 4 GBrowse link increases expression EXP 1 143,415,816 143,603,554 RGD:6480464 CTD
G Nox4 NADPH oxidase 4 GBrowse link multiple interactions EXP 1 143,415,816 143,603,554 RGD:6480464 CTD
G Npc1 Niemann-Pick disease, type C1 GBrowse link multiple interactions ISO 18 3,725,415 3,777,707 RGD:6480464 CTD
G Npc1 Niemann-Pick disease, type C1 GBrowse link affects response to substance ISO 18 3,725,415 3,777,707 RGD:6480464 CTD
G Npc1 Niemann-Pick disease, type C1 GBrowse link increases secretion ISO 18 3,725,415 3,777,707 RGD:6480464 CTD
G Nphs1 nephrosis 1, congenital, Finnish type (nephrin) GBrowse link decreases expression EXP 1 85,414,492 85,444,233 RGD:6480464 CTD
G Nphs1 nephrosis 1, congenital, Finnish type (nephrin) GBrowse link multiple interactions EXP 1 85,414,492 85,444,233 RGD:6480464 CTD
G Nppb natriuretic peptide B GBrowse link decreases expression EXP 5 165,062,348 165,063,650 RGD:6480464 CTD
G Nppb natriuretic peptide B GBrowse link increases expression ISO 5 165,062,348 165,063,650 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link decreases expression ISO 19 37,251,147 37,266,040 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link increases activity EXP 19 37,251,147 37,266,040 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link increases activity EXP 19 37,251,147 37,266,040 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link increases activity EXP 19 37,251,147 37,266,040 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link increases activity EXP 19 37,251,147 37,266,040 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link increases activity EXP 19 37,251,147 37,266,040 RGD:6480464 CTD
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 GBrowse link decreases activity ISO 18 32,371,496 32,459,145 RGD:6480464 CTD
G Nras neuroblastoma ras oncogene GBrowse link increases expression ISO 2 198,292,650 198,300,286 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link multiple interactions ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link increases cleavage ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link increases cleavage ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Pfkm phosphofructokinase, muscle GBrowse link decreases expression EXP 7 136,826,122 136,846,040 RGD:6480464 CTD
G Pik3r1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) GBrowse link affects response to substance ISO 2 32,602,673 32,675,350 RGD:6480464 CTD
G Plat plasminogen activator, tissue GBrowse link multiple interactions ISO 16 73,711,323 73,736,328 RGD:6480464 CTD
G Plk3 polo-like kinase 3 GBrowse link increases expression ISO 5 137,443,540 137,448,715 RGD:6480464 CTD
G Pparg peroxisome proliferator-activated receptor gamma GBrowse link multiple interactions EXP 4 151,492,220 151,617,331 RGD:6480464 CTD
G Pparg peroxisome proliferator-activated receptor gamma GBrowse link increases expression EXP 4 151,492,220 151,617,331 RGD:6480464 CTD
G Ppp1r13l protein phosphatase 1, regulatory subunit 13 like GBrowse link decreases response to substance ISO 1 78,727,071 78,896,831 RGD:6480464 CTD
G Prc1 protein regulator of cytokinesis 1 GBrowse link decreases expression ISO 1 136,112,674 136,133,720 RGD:6480464 CTD
G Prkcd protein kinase C, delta GBrowse link increases cleavage ISO 16 5,954,218 5,975,743 RGD:6480464 CTD
G Pten phosphatase and tensin homolog GBrowse link increases response to substance ISO 1 236,771,027 236,837,261 RGD:6480464 CTD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link increases expression EXP 13 64,427,288 64,432,978 RGD:6480464 CTD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link multiple interactions EXP 13 64,427,288 64,432,978 RGD:6480464 CTD
G Ranbp17 RAN binding protein 17 GBrowse link affects response to substance ISO 10 18,111,581 18,413,103 RGD:6480464 CTD
G Rb1 retinoblastoma 1 GBrowse link increases expression ISO 15 53,828,881 53,962,099 RGD:6480464 CTD
G Rbbp5 retinoblastoma binding protein 5 GBrowse link affects expression ISO 13 45,364,906 45,391,757 RGD:6480464 CTD
G Rbbp6 retinoblastoma binding protein 6 GBrowse link increases expression ISO 1 181,818,248 181,849,942 RGD:6480464 CTD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link multiple interactions ISO 1 208,262,669 208,273,148 RGD:6480464 CTD
G Rock1 Rho-associated coiled-coil containing protein kinase 1 GBrowse link affects expression EXP 18 1,391,751 1,511,865 RGD:6480464 CTD
G Rock1 Rho-associated coiled-coil containing protein kinase 1 GBrowse link multiple interactions EXP 18 1,391,751 1,511,865 RGD:6480464 CTD
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 GBrowse link increases phosphorylation ISO 10 76,657,024 76,698,088 RGD:6480464 CTD
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 GBrowse link multiple interactions ISO 10 76,657,024 76,698,088 RGD:6480464 CTD
G Ryr2 ryanodine receptor 2, cardiac GBrowse link multiple interactions EXP 17 68,959,042 69,544,816 RGD:6480464 CTD
G Ryr2 ryanodine receptor 2, cardiac GBrowse link decreases expression EXP 17 68,959,042 69,544,816 RGD:6480464 CTD
G Sdc1 syndecan 1 GBrowse link increases expression ISO 6 32,253,352 32,275,812 RGD:6480464 CTD
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link decreases expression ISO 12 20,931,996 20,942,374 RGD:6480464 CTD
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link multiple interactions ISO 12 20,931,996 20,942,374 RGD:6480464 CTD
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link multiple interactions ISO 12 20,931,996 20,942,374 RGD:6480464 CTD
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link decreases secretion EXP 12 20,931,996 20,942,374 RGD:6480464 CTD
G Slc25a4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 GBrowse link decreases expression EXP 16 49,353,476 49,357,271 RGD:6480464 CTD
G Slit3 slit homolog 3 (Drosophila) GBrowse link affects response to substance ISO 10 19,983,166 20,576,689 RGD:6480464 CTD
G Smpd1 sphingomyelin phosphodiesterase 1, acid lysosomal GBrowse link increases expression ISO 1 163,278,970 163,282,813 RGD:6480464 CTD
G Smpd1 sphingomyelin phosphodiesterase 1, acid lysosomal GBrowse link increases activity ISO 1 163,278,970 163,282,813 RGD:6480464 CTD
G Smpd3 sphingomyelin phosphodiesterase 3, neutral membrane GBrowse link increases expression ISO 19 36,112,166 36,195,564 RGD:6480464 CTD
G Smpd3 sphingomyelin phosphodiesterase 3, neutral membrane GBrowse link increases response to substance ISO 19 36,112,166 36,195,564 RGD:6480464 CTD
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link decreases secretion EXP 1 41,862,997 41,870,327 RGD:6480464 CTD
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link multiple interactions EXP 1 41,862,997 41,870,327 RGD:6480464 CTD
G Sp110 SP110 nuclear body protein GBrowse link affects response to substance ISO 9 84,258,232 84,279,462 RGD:6480464 CTD
G Sp3 Sp3 transcription factor GBrowse link increases expression ISO 3 55,440,985 55,485,768 RGD:6480464 CTD
G Tagln3 transgelin 3 GBrowse link affects response to substance ISO 11 56,587,304 56,600,874 RGD:6480464 CTD
G Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) GBrowse link increases expression ISO 20 4,790,363 4,800,730 RGD:6480464 CTD
G Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) GBrowse link affects response to substance ISO 20 4,770,446 4,784,488 RGD:6480464 CTD
G Tgfb1 transforming growth factor, beta 1 GBrowse link multiple interactions EXP 1 80,894,705 80,911,020 RGD:6480464 CTD
G Tgfb1 transforming growth factor, beta 1 GBrowse link increases expression EXP 1 80,894,705 80,911,020 RGD:6480464 CTD
G Tlr4 toll-like receptor 4 GBrowse link decreases response to substance ISO 5 83,564,100 83,577,735 RGD:6480464 CTD
G Tm4sf20 transmembrane 4 L six family member 20 GBrowse link affects response to substance ISO 9 82,073,815 82,087,712 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link increases expression EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b GBrowse link multiple interactions ISO 15 50,138,439 50,163,254 RGD:6480464 CTD
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 GBrowse link multiple interactions ISO 2 113,204,303 113,221,550 RGD:6480464 CTD
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 GBrowse link multiple interactions ISO 2 113,204,303 113,221,550 RGD:6480464 CTD
G Tnfsf9 tumor necrosis factor (ligand) superfamily, member 9 increases expression ISO RGD:6480464 CTD
G Tnnt2 troponin T type 2 (cardiac) GBrowse link multiple interactions EXP 13 48,872,972 48,885,815 RGD:6480464 CTD
G Tnnt2 troponin T type 2 (cardiac) GBrowse link increases secretion EXP 13 48,872,972 48,885,815 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link multiple interactions ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases expression ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases activity ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tyms thymidylate synthetase GBrowse link affects response to substance ISO 9 112,604,912 112,617,706 RGD:6480464 CTD
G Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 GBrowse link decreases expression EXP 17 40,429,806 40,434,083 RGD:6480464 CTD
G Vcam1 vascular cell adhesion molecule 1 GBrowse link increases expression EXP 2 212,277,654 212,297,376 RGD:6480464 CTD
G Vcam1 vascular cell adhesion molecule 1 GBrowse link multiple interactions EXP 2 212,277,654 212,297,376 RGD:6480464 CTD
G Vdr vitamin D (1,25- dihydroxyvitamin D3) receptor GBrowse link affects response to substance ISO 7 136,567,614 136,617,280 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link decreases expression ISO 9 10,520,730 10,536,071 RGD:6480464 CTD
G Vim vimentin GBrowse link increases expression EXP 17 87,847,280 87,855,763 RGD:6480464 CTD
G Zbtb20 zinc finger and BTB domain containing 20 GBrowse link affects response to substance ISO 11 58,662,837 59,399,213 RGD:6480464 CTD
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 492574
    role 482262
      biological role 480454
        antimicrobial agent 45711
          antibiotic 12604
            carbohydrate-containing antibiotic 303
              aminoglycoside antibiotic 285
                daunorubicin 239
Path 2
Term Annotations click to browse term
  CHEBI ontology 492574
    subatomic particle 491537
      composite particle 491537
        hadron 491537
          baryon 491537
            nucleon 491537
              atomic nucleus 491537
                atom 491537
                  main group element atom 461203
                    main group molecular entity 456122
                      s-block molecular entity 310368
                        hydrogen molecular entity 307614
                          hydrides 192538
                            organic hydride 118097
                              organic fundamental parent 118097
                                hydrocarbon 70705
                                  cyclic hydrocarbon 36630
                                    arene 35949
                                      polycyclic arene 32570
                                        ortho-fused polycyclic arene 7678
                                          acene 4531
                                            tetracene 4506
                                              daunorubicin 239
paths to the root

Contact Us |  About Us |  Jobs at RGD