ONTOLOGY REPORT - ANNOTATIONS
| Term: | 3-methyladenine |
|
| Accession: | CHEBI:38635
|
browse the term
|
| Definition: | Adenine substituted with a methyl group at position N-3. |
| Synonyms: | exact_synonym: | 3-methyl-3H-purin-6-amine |
| | related_synonym: | 3-METHYL-3H-PURIN-6-YLAMINE; 3-methyl-3H-adenine; 6-amino-3-methylpurine; C6H7N5; Cn1cnc(N)c2ncnc12; InChI=1S/C6H7N5/c1-11-3-10-5(7)4-6(11)9-2-8-4/h2-3H,7H2,1H3; InChIKey=FSASIHFSFGAIJM-UHFFFAOYSA-N |
| | alt_id: | CHEBI:1590; CHEBI:21828; CHEBI:40596 |
| | xref_casrn: | 5142-23-4 |
| | xref: | Beilstein:146087 "Beilstein Registry Number"; ChEMBL:201333 "ChEMBL COMPOUND"; ChemIDplus:5142-23-4 "CAS Registry Number"; CiteXplore:22770225 "PubMed citation"; DrugBank:DB04104 "DrugBank"; Gmelin:279109 "Gmelin Registry Number"; HMDB:HMDB11600 "HMDB"; KEGG COMPOUND:5142-23-4 "CAS Registry Number"; KEGG COMPOUND:C00913 "KEGG COMPOUND" |
| | xref_mesh: | MESH:C025946 |
| | xref: | MetaCyc:3-Methyl-Adenines "MetaCyc"; NIST Chemistry WebBook:5142-23-4 "CAS Registry Number"; PDBeChem:ADK "PDBeChem"; Reaxys:146087 "Reaxys Registry Number"; Reaxys:6503822 "Reaxys Registry Number" |
|
|
3-methyladenine
|
| G |
Aifm1 |
apoptosis-inducing factor, mitochondrion-associated 1 |
|
increases expression |
EXP |
X |
134,868,878 |
134,908,166 |
RGD:6480464 |
CTD |
| G |
Akt1 |
v-akt murine thymoma viral oncogene homolog 1 |
|
decreases phosphorylation |
ISO |
6 |
137,640,482 |
137,657,552 |
RGD:6480464 |
CTD |
| G |
Atg4al1 |
autophagy related 4A, cysteine peptidase-like 1 |
|
decreases expression |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Atg4b |
autophagy related 4B, cysteine peptidase |
|
decreases expression |
ISO |
9 |
93,054,736 |
93,063,888 |
RGD:6480464 |
CTD |
| G |
Atg5 |
autophagy related 5 |
|
multiple interactions |
ISO |
20 |
48,273,977 |
48,366,743 |
RGD:6480464 |
CTD |
| G |
Bcl2l1 |
Bcl2-like 1 |
|
multiple interactions |
ISO |
3 |
143,129,087 |
143,180,199 |
RGD:6480464 |
CTD |
| G |
Bcl2l1 |
Bcl2-like 1 |
|
multiple interactions |
ISO |
3 |
143,129,087 |
143,180,199 |
RGD:6480464 |
CTD |
| G |
Bcl2l1 |
Bcl2-like 1 |
|
increases expression |
ISO |
3 |
143,129,087 |
143,180,199 |
RGD:6480464 |
CTD |
| G |
Becn1 |
beclin 1, autophagy related |
|
multiple interactions |
ISO |
10 |
90,317,957 |
90,333,329 |
RGD:6480464 |
CTD |
| G |
Becn1 |
beclin 1, autophagy related |
|
multiple interactions |
ISO |
10 |
90,317,957 |
90,333,329 |
RGD:6480464 |
CTD |
| G |
Becn1 |
beclin 1, autophagy related |
|
decreases expression |
EXP |
10 |
90,317,957 |
90,333,329 |
RGD:6480464 |
CTD |
| G |
Becn1 |
beclin 1, autophagy related |
|
multiple interactions |
ISO |
10 |
90,317,957 |
90,333,329 |
RGD:6480464 |
CTD |
| G |
Becn1 |
beclin 1, autophagy related |
|
affects response to substance |
ISO |
10 |
90,317,957 |
90,333,329 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
multiple interactions |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
multiple interactions |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
multiple interactions |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
multiple interactions |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
increases activity |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
multiple interactions |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
multiple interactions |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
multiple interactions |
EXP |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
increases expression |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
multiple interactions |
EXP |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
increases activity |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
multiple interactions |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
increases activity |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp4 |
caspase 4, apoptosis-related cysteine peptidase |
|
increases activity |
ISO |
8 |
2,038,626 |
2,075,722 |
RGD:6480464 |
CTD |
| G |
Casp7 |
caspase 7 |
|
increases activity |
ISO |
1 |
262,689,300 |
262,721,591 |
RGD:6480464 |
CTD |
| G |
Casp8 |
caspase 8 |
|
multiple interactions |
ISO |
9 |
57,389,353 |
57,437,803 |
RGD:6480464 |
CTD |
| G |
Casp9 |
caspase 9, apoptosis-related cysteine peptidase |
|
multiple interactions |
ISO |
5 |
160,704,234 |
160,721,796 |
RGD:6480464 |
CTD |
| G |
Casp9 |
caspase 9, apoptosis-related cysteine peptidase |
|
multiple interactions |
EXP |
5 |
160,704,234 |
160,721,796 |
RGD:6480464 |
CTD |
| G |
Casp9 |
caspase 9, apoptosis-related cysteine peptidase |
|
multiple interactions |
EXP |
5 |
160,704,234 |
160,721,796 |
RGD:6480464 |
CTD |
| G |
Cdx2 |
caudal type homeo box 2 |
|
increases expression |
ISO |
12 |
8,296,103 |
8,303,643 |
RGD:6480464 |
CTD |
| G |
Cycs |
cytochrome c, somatic |
|
multiple interactions |
ISO |
4 |
78,825,878 |
78,827,978 |
RGD:6480464 |
CTD |
| G |
Gabarap |
GABA(A) receptor-associated protein |
|
decreases expression |
ISO |
10 |
56,837,772 |
56,840,707 |
RGD:6480464 |
CTD |
| G |
Hif1a |
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
|
multiple interactions |
ISO |
6 |
96,419,024 |
96,463,891 |
RGD:6480464 |
CTD |
| G |
Itgam |
integrin, alpha M |
|
multiple interactions |
ISO |
1 |
187,334,413 |
187,385,583 |
RGD:6480464 |
CTD |
| G |
Map1lc3a |
microtubule-associated protein 1 light chain 3 alpha |
|
multiple interactions |
ISO |
3 |
145,758,939 |
145,760,532 |
RGD:6480464 |
CTD |
| G |
Map1lc3a |
microtubule-associated protein 1 light chain 3 alpha |
|
affects metabolic processing |
ISO |
3 |
145,758,939 |
145,760,532 |
RGD:6480464 |
CTD |
| G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
|
multiple interactions |
EXP |
19 |
51,847,187 |
51,854,858 |
RGD:6480464 |
CTD |
| G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
|
decreases expression |
ISO |
19 |
51,847,187 |
51,854,858 |
RGD:6480464 |
CTD |
| G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
|
multiple interactions |
ISO |
19 |
51,847,187 |
51,854,858 |
RGD:6480464 |
CTD |
| G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
|
multiple interactions |
ISO |
19 |
51,847,187 |
51,854,858 |
RGD:6480464 |
CTD |
| G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
|
multiple interactions |
ISO |
19 |
51,847,187 |
51,854,858 |
RGD:6480464 |
CTD |
| G |
Map3k5 |
mitogen-activated protein kinase kinase kinase 5 |
|
affects response to substance |
ISO |
1 |
15,205,361 |
15,346,422 |
RGD:6480464 |
CTD |
| G |
Map3k5 |
mitogen-activated protein kinase kinase kinase 5 |
|
multiple interactions |
ISO |
1 |
15,205,361 |
15,346,422 |
RGD:6480464 |
CTD |
| G |
Mtor |
mechanistic target of rapamycin (serine/threonine kinase) |
|
multiple interactions |
ISO |
5 |
165,531,402 |
165,640,899 |
RGD:6480464 |
CTD |
| G |
Nanog |
Nanog homeobox |
|
increases expression |
ISO |
4 |
159,190,786 |
159,198,160 |
RGD:6480464 |
CTD |
| G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
|
multiple interactions |
ISO |
13 |
96,309,670 |
96,341,486 |
RGD:6480464 |
CTD |
| G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
|
increases cleavage |
ISO |
13 |
96,309,670 |
96,341,486 |
RGD:6480464 |
CTD |
| G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
|
multiple interactions |
ISO |
13 |
96,309,670 |
96,341,486 |
RGD:6480464 |
CTD |
| G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
|
multiple interactions |
ISO |
13 |
96,309,670 |
96,341,486 |
RGD:6480464 |
CTD |
| G |
Pik3c3 |
phosphatidylinositol 3-kinase, catalytic subunit type 3 |
|
multiple interactions |
ISO |
18 |
22,495,197 |
22,579,656 |
RGD:6480464 |
CTD |
| G |
Pik3c3 |
phosphatidylinositol 3-kinase, catalytic subunit type 3 |
|
multiple interactions |
ISO |
18 |
22,495,197 |
22,579,656 |
RGD:6480464 |
CTD |
| G |
Pou5f1 |
POU class 5 homeobox 1 |
|
increases expression |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Sox2 |
SRY (sex determining region Y)-box 2 |
|
increases expression |
ISO |
2 |
120,969,021 |
120,971,430 |
RGD:6480464 |
CTD |
| G |
Sqstm1 |
sequestosome 1 |
|
increases expression |
ISO |
10 |
35,751,300 |
35,762,630 |
RGD:6480464 |
CTD |
Term paths to the root
|