ONTOLOGY REPORT - ANNOTATIONS

Term:penams
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Accession:CHEBI:35992 term browser browse the term
Definition:Natural and synthetic antibiotics containing the 4-thia-1-azabicyclo[3.2.0]heptan-7-one structure, generally assumed to have the 5R configuration unless otherwise specified.

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amoxicillin term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 GBrowse link increases expression ISO 7 113,043,365 113,049,779 RGD:6480464 CTD
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression ISO RGD:6480464 CTD
ampicillin term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Abcc3 ATP-binding cassette, subfamily C (CFTR/MRP), member 3 GBrowse link decreases expression ISO 10 82,986,552 83,030,799 RGD:6480464 CTD
G Abcc4 ATP-binding cassette, subfamily C (CFTR/MRP), member 4 GBrowse link increases transport ISO 15 103,384,848 103,611,238 RGD:6480464 CTD
G Agpat9 1-acylglycerol-3-phosphate O-acyltransferase 9 GBrowse link decreases expression ISO 14 9,998,566 10,050,154 RGD:6480464 CTD
G Akr1b10 aldo-keto reductase family 1, member B10 (aldose reductase) GBrowse link decreases expression ISO 4 61,755,871 61,771,264 RGD:6480464 CTD
G Akr1c2 aldo-keto reductase family 1, member C2 GBrowse link decreases expression ISO 17 77,034,737 77,081,406 RGD:6480464 CTD
G Amot angiomotin GBrowse link increases expression ISO X 33,018,434 33,062,515 RGD:6480464 CTD
G Ankrd1 ankyrin repeat domain 1 GBrowse link increases expression ISO 1 240,316,123 240,324,804 RGD:6480464 CTD
G Aqp3 aquaporin 3 GBrowse link decreases expression ISO 5 58,501,642 58,507,159 RGD:6480464 CTD
G Arg1 arginase, liver GBrowse link increases expression ISO 1 20,998,894 21,011,275 RGD:6480464 CTD
G Arhgdia Rho GDP dissociation inhibitor (GDI) alpha GBrowse link increases expression ISO 10 109,967,771 109,971,260 RGD:6480464 CTD
G Arrdc3 arrestin domain containing 3 decreases expression ISO RGD:6480464 CTD
G Asns asparagine synthetase (glutamine-hydrolyzing) GBrowse link decreases expression ISO 4 32,758,866 32,776,220 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link increases response to substance ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Calr calreticulin GBrowse link increases expression ISO 19 24,964,775 24,969,670 RGD:6480464 CTD
G Car9 carbonic anhydrase 9 GBrowse link increases expression ISO 5 59,986,413 59,993,015 RGD:6480464 CTD
G Ccpg1 cell cycle progression 1 GBrowse link decreases expression ISO 8 77,724,315 77,768,060 RGD:6480464 CTD
G Chst15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 GBrowse link increases expression ISO 1 191,708,603 191,737,958 RGD:6480464 CTD
G Ckb creatine kinase, brain GBrowse link increases expression ISO 6 136,452,215 136,455,122 RGD:6480464 CTD
G Clgn calmegin GBrowse link decreases expression ISO 19 26,404,126 26,436,081 RGD:6480464 CTD
G Clic3 chloride intracellular channel 3 GBrowse link increases expression ISO 3 3,622,894 3,624,805 RGD:6480464 CTD
G Cp ceruloplasmin (ferroxidase) GBrowse link increases expression ISO 2 105,086,278 105,135,367 RGD:6480464 CTD
G Creb3l3 cAMP responsive element binding protein 3-like 3 GBrowse link decreases expression ISO 7 10,106,525 10,114,960 RGD:6480464 CTD
G Csta cystatin A (stefin A) GBrowse link decreases expression ISO 11 66,456,248 66,467,253 RGD:6480464 CTD
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 GBrowse link decreases expression ISO 8 61,462,207 61,468,237 RGD:6480464 CTD
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 GBrowse link decreases expression ISO 3 161,542,131 161,553,801 RGD:6480464 CTD
G Cyr61 cysteine-rich, angiogenic inducer, 61 GBrowse link increases expression ISO 2 243,824,303 243,827,262 RGD:6480464 CTD
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 GBrowse link increases expression ISO 1 234,392,743 234,396,426 RGD:6480464 CTD
G Dusp1 dual specificity phosphatase 1 GBrowse link increases expression ISO 10 16,942,913 16,945,696 RGD:6480464 CTD
G Dusp7 dual specificity phosphatase 7 GBrowse link increases expression ISO 8 111,510,358 111,515,989 RGD:6480464 CTD
G Edn1 endothelin 1 GBrowse link increases expression ISO 17 28,303,886 28,309,775 RGD:6480464 CTD
G Esm1 endothelial cell-specific molecule 1 GBrowse link decreases expression ISO 2 44,626,010 44,634,748 RGD:6480464 CTD
G Filip1l filamin A interacting protein 1-like GBrowse link increases expression ISO 11 43,788,676 43,859,932 RGD:6480464 CTD
G Fxyd1 FXYD domain-containing ion transport regulator 1 GBrowse link increases expression ISO 1 86,095,551 86,098,079 RGD:6480464 CTD
G Gclc glutamate-cysteine ligase, catalytic subunit GBrowse link decreases expression ISO 8 82,724,429 82,762,848 RGD:6480464 CTD
G Gclm glutamate cysteine ligase, modifier subunit GBrowse link increases expression ISO 2 218,895,434 218,915,491 RGD:6480464 CTD
G Gclm glutamate cysteine ligase, modifier subunit GBrowse link decreases expression ISO 2 218,895,434 218,915,491 RGD:6480464 CTD
G Hoxd1 homeo box D1 GBrowse link increases expression ISO 3 57,377,839 57,379,978 RGD:6480464 CTD
G Ifrd1 interferon-related developmental regulator 1 decreases expression ISO RGD:6480464 CTD
G Igfbp3 insulin-like growth factor binding protein 3 GBrowse link increases expression ISO 14 87,959,153 87,967,085 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link multiple interactions EXP 3 116,964,422 116,970,867 RGD:6480464 CTD
G Jdp2 Jun dimerization protein 2 GBrowse link decreases expression ISO 6 109,708,745 109,740,375 RGD:6480464 CTD
G Jund jun D proto-oncogene GBrowse link increases expression ISO 16 19,239,694 19,241,529 RGD:6480464 CTD
G Lox lysyl oxidase GBrowse link increases expression ISO 18 47,896,674 47,970,829 RGD:6480464 CTD
G Lppr1 lipid phosphate phosphatase-related protein type 1 GBrowse link increases expression ISO 5 65,982,029 66,115,218 RGD:6480464 CTD
G Maz MYC-associated zinc finger protein (purine-binding transcription factor) GBrowse link increases expression ISO 1 186,201,083 186,204,364 RGD:6480464 CTD
G Mpo myeloperoxidase GBrowse link multiple interactions EXP 10 76,085,872 76,097,012 RGD:6480464 CTD
G Mpo myeloperoxidase GBrowse link multiple interactions EXP 10 76,085,872 76,097,012 RGD:6480464 CTD
G Mpo myeloperoxidase GBrowse link multiple interactions EXP 10 76,085,872 76,097,012 RGD:6480464 CTD
G Mpo myeloperoxidase GBrowse link multiple interactions EXP 10 76,085,872 76,097,012 RGD:6480464 CTD
G Mtss1l metastasis suppressor 1-like GBrowse link increases expression ISO 19 40,640,947 40,661,240 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link multiple interactions EXP 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link multiple interactions EXP 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link multiple interactions EXP 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link multiple interactions EXP 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link multiple interactions EXP 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link multiple interactions EXP 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link multiple interactions EXP 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link multiple interactions EXP 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link increases expression ISO 19 37,251,147 37,266,040 RGD:6480464 CTD
G Pa2g4 proliferation-associated 2G4 GBrowse link increases expression ISO 7 1,846,628 1,854,096 RGD:6480464 CTD
G Pabpc1l poly(A) binding protein, cytoplasmic 1-like GBrowse link decreases expression ISO 3 154,959,889 154,992,338 RGD:6480464 CTD
G Pdp2 pyruvate dehyrogenase phosphatase catalytic subunit 2 GBrowse link increases expression ISO 19 307,961 312,004 RGD:6480464 CTD
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 GBrowse link increases expression ISO 17 78,241,182 78,268,272 RGD:6480464 CTD
G Pgc progastricsin (pepsinogen C) GBrowse link increases expression ISO 9 8,723,620 8,731,837 RGD:6480464 CTD
G Pgd phosphogluconate dehydrogenase decreases activity EXP RGD:6480464 CTD
G Pir pirin (iron-binding nuclear protein) GBrowse link increases expression ISO X 50,864,981 50,974,861 RGD:6480464 CTD
G Pkm pyruvate kinase, muscle GBrowse link increases expression ISO 8 63,486,492 63,508,016 RGD:6480464 CTD
G Pon1 paraoxonase 1 GBrowse link decreases activity ISO 4 29,936,314 29,964,821 RGD:6480464 CTD
G Pon1 paraoxonase 1 GBrowse link decreases activity ISO 4 29,936,314 29,964,821 RGD:6480464 CTD
G Ptgr1 prostaglandin reductase 1 GBrowse link decreases expression ISO 5 77,010,809 77,029,326 RGD:6480464 CTD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link multiple interactions EXP 13 64,427,288 64,432,978 RGD:6480464 CTD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link multiple interactions EXP 13 64,427,288 64,432,978 RGD:6480464 CTD
G Ptms parathymosin GBrowse link increases expression ISO 4 161,041,242 161,045,145 RGD:6480464 CTD
G Rgcc regulator of cell cycle GBrowse link increases expression ISO 15 60,451,831 60,452,229 RGD:6480464 CTD
G Sgk2 serum/glucocorticoid regulated kinase 2 GBrowse link decreases expression ISO 3 153,849,825 153,890,111 RGD:6480464 CTD
G Slc1a2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 GBrowse link increases expression ISO 3 87,870,558 87,992,401 RGD:6480464 CTD
G Slc22a15 solute carrier family 22, member 15 GBrowse link decreases expression ISO 2 196,953,291 197,013,763 RGD:6480464 CTD
G Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 GBrowse link increases expression ISO 4 159,210,116 159,221,169 RGD:6480464 CTD
G Slc6a14 solute carrier family 6 (amino acid transporter), member 14 GBrowse link increases expression ISO X 12,048,993 12,072,434 RGD:6480464 CTD
G Slc6a8 solute carrier family 6 (neurotransmitter transporter, creatine), member 8 GBrowse link increases expression ISO X 159,570,789 159,580,093 RGD:6480464 CTD
G Slc7a11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 GBrowse link decreases expression ISO 2 139,241,142 139,317,101 RGD:6480464 CTD
G Smim14 small integral membrane protein 14 GBrowse link decreases expression ISO 14 45,477,213 45,520,785 RGD:6480464 CTD
G Srxn1 sulfiredoxin 1 GBrowse link decreases expression ISO 3 142,457,352 142,462,725 RGD:6480464 CTD
G Tagln transgelin GBrowse link increases expression ISO 8 48,902,208 48,907,682 RGD:6480464 CTD
G Timp1 TIMP metallopeptidase inhibitor 1 GBrowse link decreases expression ISO X 12,542,496 12,547,094 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tpm4 tropomyosin 4 GBrowse link increases expression ISO 16 18,108,914 18,122,956 RGD:6480464 CTD
G Trim16 tripartite motif-containing 16 GBrowse link increases expression ISO 10 48,987,004 49,009,696 RGD:6480464 CTD
G Ttyh3 tweety homolog 3 (Drosophila) GBrowse link increases expression ISO 12 14,463,541 14,491,939 RGD:6480464 CTD
G Tube1 tubulin, epsilon 1 GBrowse link decreases expression ISO 20 43,280,097 43,298,415 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link multiple interactions EXP 9 10,520,730 10,536,071 RGD:6480464 CTD
G Vldlr very low density lipoprotein receptor GBrowse link decreases expression ISO 1 230,666,736 230,697,748 RGD:6480464 CTD
benzylpenicillin term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 increases activity EXP RGD:6480464 CTD
G Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 multiple interactions ISO RGD:6480464 CTD
G Abcc4 ATP-binding cassette, subfamily C (CFTR/MRP), member 4 GBrowse link increases transport ISO 15 103,384,848 103,611,238 RGD:6480464 CTD
G Cd86 CD86 molecule GBrowse link increases expression ISO 11 66,215,233 66,238,882 RGD:6480464 CTD
G Gclm glutamate cysteine ligase, modifier subunit GBrowse link increases expression ISO 2 218,895,434 218,915,491 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link increases expression ISO 3 116,964,422 116,970,867 RGD:6480464 CTD
G Nes nestin GBrowse link increases expression EXP 2 180,051,907 180,060,947 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link increases expression ISO 19 37,251,147 37,266,040 RGD:6480464 CTD
G Pgd phosphogluconate dehydrogenase decreases activity EXP RGD:6480464 CTD
G Pir pirin (iron-binding nuclear protein) GBrowse link increases expression ISO X 50,864,981 50,974,861 RGD:6480464 CTD
G Slc22a12 solute carrier family 22 (organic anion/urate transporter), member 12 GBrowse link multiple interactions ISO 1 209,320,804 209,327,918 RGD:6480464 CTD
G Slc22a6 solute carrier family 22 (organic anion transporter), member 6 GBrowse link multiple interactions ISO 1 211,294,178 211,302,398 RGD:6480464 CTD
G Slc22a8 solute carrier family 22 (organic anion transporter), member 8 GBrowse link multiple interactions EXP 1 211,269,366 211,287,596 RGD:6480464 CTD
G Slc22a8 solute carrier family 22 (organic anion transporter), member 8 GBrowse link multiple interactions EXP 1 211,269,366 211,287,596 RGD:6480464 CTD
G Slc22a8 solute carrier family 22 (organic anion transporter), member 8 GBrowse link increases uptake ISO 1 211,269,366 211,287,596 RGD:6480464 CTD
G Trim16 tripartite motif-containing 16 GBrowse link increases expression ISO 10 48,987,004 49,009,696 RGD:6480464 CTD
cloxacillin term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 decreases activity ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 decreases activity EXP RGD:6480464 CTD
dicloxacillin term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 decreases activity ISO RGD:6480464 CTD
G Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) GBrowse link increases expression ISO 14 18,690,339 18,692,118 RGD:6480464 CTD
G Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) GBrowse link multiple interactions ISO 14 18,690,339 18,692,118 RGD:6480464 CTD
G Cxcl2 chemokine (C-X-C motif) ligand 2 GBrowse link multiple interactions ISO 14 18,677,129 18,679,175 RGD:6480464 CTD
G Icam1 intercellular adhesion molecule 1 GBrowse link increases expression ISO 8 20,040,177 20,051,939 RGD:6480464 CTD
G Il4 interleukin 4 GBrowse link increases response to substance ISO 10 39,074,582 39,080,134 RGD:6480464 CTD
G Il4 interleukin 4 GBrowse link increases expression ISO 10 39,074,582 39,080,134 RGD:6480464 CTD
flucloxacillin term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Crp C-reactive protein, pentraxin-related GBrowse link multiple interactions ISO 13 88,702,243 88,703,153 RGD:6480464 CTD
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 GBrowse link increases metabolic processing ISO 12 9,517,016 9,541,000 RGD:6480464 CTD
G RT1-CE7 RT1 class I, locus CE7 GBrowse link affects response to substance ISO 20 3,410,094 3,413,041 RGD:6480464 CTD
phenoxymethylpenicillin term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Gclm glutamate cysteine ligase, modifier subunit GBrowse link increases expression ISO 2 218,895,434 218,915,491 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link increases expression ISO 3 116,964,422 116,970,867 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link increases expression ISO 19 37,251,147 37,266,040 RGD:6480464 CTD
G Pir pirin (iron-binding nuclear protein) GBrowse link increases expression ISO X 50,864,981 50,974,861 RGD:6480464 CTD
G Trim16 tripartite motif-containing 16 GBrowse link increases expression ISO 10 48,987,004 49,009,696 RGD:6480464 CTD
piperacillin term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Abcc4 ATP-binding cassette, subfamily C (CFTR/MRP), member 4 GBrowse link increases transport ISO 15 103,384,848 103,611,238 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link multiple interactions EXP 3 116,964,422 116,970,867 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
sulbactam term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Abcc4 ATP-binding cassette, subfamily C (CFTR/MRP), member 4 GBrowse link increases transport ISO 15 103,384,848 103,611,238 RGD:6480464 CTD
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 501881
    role 491510
      biological role 489686
        antimicrobial agent 46038
          antibiotic 12635
            heterocyclic antibiotic 1550
              organonitrogen heterocyclic antibiotic 1459
                beta-lactam antibiotic 687
                  penams 131
                    penam + 0
                    penamcarboxylate + 0
                    penicillanic acid ester + 0
                    penicillanic acids + 131
Path 2
Term Annotations click to browse term
  CHEBI ontology 501881
    subatomic particle 500845
      composite particle 500845
        hadron 500845
          baryon 500845
            nucleon 500845
              atomic nucleus 500845
                atom 500845
                  main group element atom 470301
                    p-block element atom 467779
                      carbon group element atom 419149
                        carbon atom 415667
                          organic molecular entity 415660
                            organic group 171184
                              organic divalent group 169999
                                organodiyl group 169999
                                  carbonyl group 169689
                                    carbonyl compound 169689
                                      pseudoketone 13104
                                        cyclic pseudoketone 12715
                                          lactam 1879
                                            beta-lactam 687
                                              beta-lactam antibiotic 687
                                                penams 131
                                                  penam + 0
                                                  penamcarboxylate + 0
                                                  penicillanic acid ester + 0
                                                  penicillanic acids + 131
paths to the root

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