ONTOLOGY REPORT - ANNOTATIONS
| Term: | chloroform |
|
| Accession: | CHEBI:35255
|
browse the term
|
| Definition: | A chloromethane that has formula CHCl3. |
| Synonyms: | related_synonym: | 1,1,1-trichloromethane; CHCl3; InChI=1S/CHCl3/c2-1(3)4/h1H; InChIKey=HEDRZPFGACZZDS-UHFFFAOYSA-N; Trichlormethan; [H]C(Cl)(Cl)Cl; chloroforme; chloroformium pro narcosi; trichloromethane |
| | alt_id: | CHEBI:23143; CHEBI:34628 |
| | xref_casrn: | 67-66-3 |
| | xref: | ChEMBL:167839 "ChEMBL COMPOUND"; ChemIDplus:1731042 "Beilstein Registry Number"; ChemIDplus:67-66-3 "CAS Registry Number"; Gmelin:1837 "Gmelin Registry Number"; KEGG COMPOUND:67-66-3 "CAS Registry Number"; KEGG COMPOUND:C13827 "KEGG COMPOUND" |
| | xref_mesh: | MESH:D002725 |
| | xref: | NIST Chemistry WebBook:67-66-3 "CAS Registry Number"; UM-BBD:c0595 "UM-BBD compID"; Wikipedia:Chloroform "Wikipedia" |
|
|
chloroform
|
| G |
Abcb11 |
ATP-binding cassette, sub-family B (MDR/TAP), member 11 |
|
decreases expression |
ISO |
2 |
69,076,339 |
69,180,673 |
RGD:6480464 |
CTD |
| G |
Abcb1a |
ATP-binding cassette, sub-family B (MDR/TAP), member 1A |
|
increases expression |
ISO |
5 |
8,660,092 |
8,748,570 |
RGD:6480464 |
CTD |
| G |
Abcb1a |
ATP-binding cassette, sub-family B (MDR/TAP), member 1A |
|
increases expression |
ISO |
5 |
8,660,092 |
8,748,570 |
RGD:6480464 |
CTD |
| G |
Abcb1b |
ATP-binding cassette, sub-family B (MDR/TAP), member 1B |
|
increases expression |
ISO |
5 |
8,798,147 |
8,866,314 |
RGD:6480464 |
CTD |
| G |
Abcc3 |
ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
|
increases expression |
ISO |
11 |
94,204,609 |
94,254,290 |
RGD:6480464 |
CTD |
| G |
Acadm |
acyl-Coenzyme A dehydrogenase, medium chain |
|
decreases expression |
ISO |
3 |
153,585,323 |
153,607,396 |
RGD:6480464 |
CTD |
| G |
Acsl1 |
acyl-CoA synthetase long-chain family member 1 |
|
decreases expression |
ISO |
8 |
47,556,396 |
47,621,404 |
RGD:6480464 |
CTD |
| G |
Aldh1a1 |
aldehyde dehydrogenase family 1, subfamily A1 |
|
increases expression |
ISO |
19 |
20,676,472 |
20,717,952 |
RGD:6480464 |
CTD |
| G |
Aldh3a2 |
aldehyde dehydrogenase family 3, subfamily A2 |
|
decreases expression |
ISO |
11 |
61,058,257 |
61,080,629 |
RGD:6480464 |
CTD |
| G |
Aldoa |
aldolase A, fructose-bisphosphate |
|
increases expression |
ISO |
7 |
133,938,748 |
133,943,961 |
RGD:6480464 |
CTD |
| G |
Anxa2 |
annexin A2 |
|
increases expression |
ISO |
9 |
69,301,490 |
69,339,592 |
RGD:6480464 |
CTD |
| G |
Apex1 |
apurinic/apyrimidinic endonuclease 1 |
|
increases expression |
ISO |
14 |
51,544,696 |
51,546,813 |
RGD:6480464 |
CTD |
| G |
Asl |
argininosuccinate lyase |
|
increases expression |
ISO |
5 |
130,487,373 |
130,500,201 |
RGD:6480464 |
CTD |
| G |
Btg2 |
B cell translocation gene 2, anti-proliferative |
|
increases expression |
ISO |
1 |
135,971,442 |
135,975,732 |
RGD:6480464 |
CTD |
| G |
Btg2 |
B cell translocation gene 2, anti-proliferative |
|
increases expression |
EXP |
1 |
135,971,442 |
135,975,732 |
RGD:6480464 |
CTD |
| G |
Btg2 |
B cell translocation gene 2, anti-proliferative |
|
increases expression |
ISO |
1 |
135,971,442 |
135,975,732 |
RGD:6480464 |
CTD |
| G |
Btg2 |
B cell translocation gene 2, anti-proliferative |
|
increases expression |
ISO |
1 |
135,971,442 |
135,975,732 |
RGD:6480464 |
CTD |
| G |
Calu |
calumenin |
|
increases expression |
ISO |
6 |
29,298,119 |
29,326,675 |
RGD:6480464 |
CTD |
| G |
Calu |
calumenin |
|
increases expression |
ISO |
6 |
29,298,119 |
29,326,675 |
RGD:6480464 |
CTD |
| G |
Cat |
catalase |
|
decreases expression |
ISO |
2 |
103,294,061 |
103,325,310 |
RGD:6480464 |
CTD |
| G |
Ccl2 |
chemokine (C-C motif) ligand 2 |
|
increases expression |
ISO |
11 |
81,849,079 |
81,850,954 |
RGD:6480464 |
CTD |
| G |
Ccng1 |
cyclin G1 |
|
increases expression |
ISO |
11 |
40,562,054 |
40,568,788 |
RGD:6480464 |
CTD |
| G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A (P21) |
|
increases expression |
ISO |
17 |
29,227,931 |
29,237,667 |
RGD:6480464 |
CTD |
| G |
Ces2h |
carboxylesterase 2H |
|
increases expression |
ISO |
8 |
107,524,753 |
107,544,310 |
RGD:6480464 |
CTD |
| G |
Clu |
clusterin |
|
increases expression |
ISO |
14 |
66,587,320 |
66,600,382 |
RGD:6480464 |
CTD |
| G |
Ctsl |
cathepsin L |
|
increases expression |
ISO |
13 |
64,464,522 |
64,471,614 |
RGD:6480464 |
CTD |
| G |
Cyp2d9 |
cytochrome P450, family 2, subfamily d, polypeptide 9 |
|
decreases expression |
ISO |
15 |
82,282,807 |
82,287,257 |
RGD:6480464 |
CTD |
| G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
|
increases metabolic processing |
ISO |
7 |
147,949,731 |
147,960,880 |
RGD:6480464 |
CTD |
| G |
Cyp4f15 |
cytochrome P450, family 4, subfamily f, polypeptide 15 |
|
decreases expression |
EXP |
17 |
32,822,604 |
32,840,294 |
RGD:6480464 |
CTD |
| G |
Ddit3 |
DNA-damage inducible transcript 3 |
|
increases expression |
ISO |
10 |
126,727,849 |
126,733,344 |
RGD:6480464 |
CTD |
| G |
Fabp1 |
fatty acid binding protein 1, liver |
|
decreases expression |
ISO |
6 |
71,149,882 |
71,155,017 |
RGD:6480464 |
CTD |
| G |
Fads1 |
fatty acid desaturase 1 |
|
decreases expression |
ISO |
19 |
10,257,378 |
10,271,364 |
RGD:6480464 |
CTD |
| G |
Fga |
fibrinogen alpha chain |
|
increases expression |
ISO |
3 |
82,830,075 |
82,837,549 |
RGD:6480464 |
CTD |
| G |
Fmo1 |
flavin containing monooxygenase 1 |
|
decreases expression |
ISO |
1 |
164,759,692 |
164,796,679 |
RGD:6480464 |
CTD |
| G |
Fos |
FBJ osteosarcoma oncogene |
|
increases expression |
EXP |
12 |
86,814,851 |
86,818,219 |
RGD:6480464 |
CTD |
| G |
Gadd45a |
growth arrest and DNA-damage-inducible 45 alpha |
|
increases expression |
ISO |
6 |
66,985,090 |
66,987,401 |
RGD:6480464 |
CTD |
| G |
Gck |
glucokinase |
|
increases expression |
ISO |
11 |
5,800,826 |
5,849,602 |
RGD:6480464 |
CTD |
| G |
Gjb1 |
gap junction protein, beta 1 |
|
decreases expression |
ISO |
X |
98,572,676 |
98,580,964 |
RGD:6480464 |
CTD |
| G |
Gpt |
glutamic pyruvic transaminase, soluble |
|
multiple interactions |
EXP |
15 |
76,527,194 |
76,530,105 |
RGD:6480464 |
CTD |
| G |
Gpt |
glutamic pyruvic transaminase, soluble |
|
increases activity |
EXP |
15 |
76,527,194 |
76,530,105 |
RGD:6480464 |
CTD |
| G |
Gpt |
glutamic pyruvic transaminase, soluble |
|
increases activity |
ISO |
15 |
76,527,194 |
76,530,105 |
RGD:6480464 |
CTD |
| G |
Gpt |
glutamic pyruvic transaminase, soluble |
|
multiple interactions |
ISO |
15 |
76,527,194 |
76,530,105 |
RGD:6480464 |
CTD |
| G |
Gpx1 |
glutathione peroxidase 1 |
|
decreases expression |
ISO |
9 |
108,241,607 |
108,242,671 |
RGD:6480464 |
CTD |
| G |
Gsr |
glutathione reductase |
|
increases expression |
EXP |
8 |
34,763,710 |
34,808,634 |
RGD:6480464 |
CTD |
| G |
Gstm3 |
glutathione S-transferase, mu 3 |
|
decreases expression |
ISO |
3 |
107,766,614 |
107,772,076 |
RGD:6480464 |
CTD |
| G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
|
increases expression |
ISO |
11 |
46,553,725 |
46,593,080 |
RGD:6480464 |
CTD |
| G |
Hcn2 |
hyperpolarization-activated, cyclic nucleotide-gated K+ 2 |
|
decreases activity |
ISO |
10 |
79,179,379 |
79,198,853 |
RGD:6480464 |
CTD |
| G |
Hibadh |
3-hydroxyisobutyrate dehydrogenase |
|
decreases expression |
ISO |
6 |
52,496,224 |
52,590,294 |
RGD:6480464 |
CTD |
| G |
Hmox1 |
heme oxygenase (decycling) 1 |
|
increases expression |
EXP |
8 |
77,617,517 |
77,624,492 |
RGD:6480464 |
CTD |
| G |
Hspa1a |
heat shock protein 1A |
|
increases expression |
ISO |
17 |
35,106,304 |
35,109,101 |
RGD:6480464 |
CTD |
| G |
Icam1 |
intercellular adhesion molecule 1 |
|
increases expression |
ISO |
9 |
20,820,404 |
20,833,241 |
RGD:6480464 |
CTD |
| G |
Ifng |
interferon gamma |
|
decreases expression |
EXP |
10 |
117,878,103 |
117,882,948 |
RGD:6480464 |
CTD |
| G |
Il13 |
interleukin 13 |
|
increases expression |
EXP |
11 |
53,444,825 |
53,448,204 |
RGD:6480464 |
CTD |
| G |
Il4 |
interleukin 4 |
|
decreases expression |
EXP |
11 |
53,425,962 |
53,432,167 |
RGD:6480464 |
CTD |
| G |
Il5 |
interleukin 5 |
|
increases expression |
EXP |
11 |
53,534,296 |
53,538,605 |
RGD:6480464 |
CTD |
| G |
Il8 |
interleukin 8 |
|
increases expression |
ISO |
5 |
91,223,560 |
91,232,093 |
RGD:6480464 |
CTD |
| G |
Kcnh2 |
potassium voltage-gated channel, subfamily H (eag-related), member 2 |
|
decreases activity |
ISO |
5 |
23,825,407 |
23,857,422 |
RGD:6480464 |
CTD |
| G |
Krt18 |
keratin 18 |
|
increases expression |
ISO |
15 |
101,858,647 |
101,862,457 |
RGD:6480464 |
CTD |
| G |
Krt8 |
keratin 8 |
|
increases expression |
ISO |
15 |
101,827,142 |
101,834,773 |
RGD:6480464 |
CTD |
| G |
Lbp |
lipopolysaccharide binding protein |
|
increases expression |
ISO |
2 |
158,132,229 |
158,158,588 |
RGD:6480464 |
CTD |
| G |
Lgals3 |
lectin, galactose binding, soluble 3 |
|
increases expression |
ISO |
14 |
47,993,535 |
48,005,842 |
RGD:6480464 |
CTD |
| G |
Lipc |
lipase, hepatic |
|
decreases expression |
ISO |
9 |
70,645,935 |
70,782,615 |
RGD:6480464 |
CTD |
| G |
Lpl |
lipoprotein lipase |
|
increases expression |
ISO |
8 |
71,404,454 |
71,430,831 |
RGD:6480464 |
CTD |
| G |
Maob |
monoamine oxidase B |
|
decreases expression |
ISO |
X |
16,286,407 |
16,394,492 |
RGD:6480464 |
CTD |
| G |
Mgmt |
O-6-methylguanine-DNA methyltransferase |
|
increases expression |
ISO |
7 |
144,086,294 |
144,319,871 |
RGD:6480464 |
CTD |
| G |
Mug1 |
murinoglobulin 1 |
|
decreases expression |
ISO |
6 |
121,788,559 |
121,839,075 |
RGD:6480464 |
CTD |
| G |
Myc |
myelocytomatosis oncogene |
|
increases expression |
EXP |
15 |
61,816,896 |
61,821,916 |
RGD:6480464 |
CTD |
| G |
Myc |
myelocytomatosis oncogene |
|
multiple interactions |
EXP |
15 |
61,816,896 |
61,821,916 |
RGD:6480464 |
CTD |
| G |
Myc |
myelocytomatosis oncogene |
|
multiple interactions |
EXP |
15 |
61,816,896 |
61,821,916 |
RGD:6480464 |
CTD |
| G |
Myc |
myelocytomatosis oncogene |
|
decreases methylation |
EXP |
15 |
61,816,896 |
61,821,916 |
RGD:6480464 |
CTD |
| G |
Myc |
myelocytomatosis oncogene |
|
increases expression |
EXP |
15 |
61,816,896 |
61,821,916 |
RGD:6480464 |
CTD |
| G |
Myc |
myelocytomatosis oncogene |
|
increases expression |
ISO |
15 |
61,816,896 |
61,821,916 |
RGD:6480464 |
CTD |
| G |
Myc |
myelocytomatosis oncogene |
|
decreases methylation |
EXP |
15 |
61,816,896 |
61,821,916 |
RGD:6480464 |
CTD |
| G |
Nfkb1 |
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 |
|
multiple interactions |
ISO |
3 |
135,247,619 |
135,354,511 |
RGD:6480464 |
CTD |
| G |
Nfkbib |
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta |
|
increases expression |
ISO |
7 |
29,543,270 |
29,551,543 |
RGD:6480464 |
CTD |
| G |
Odc1 |
ornithine decarboxylase, structural 1 |
|
increases expression |
ISO |
12 |
17,551,679 |
17,558,308 |
RGD:6480464 |
CTD |
| G |
Otc |
ornithine transcarbamylase |
|
decreases expression |
ISO |
X |
9,829,485 |
9,898,150 |
RGD:6480464 |
CTD |
| G |
Pcna |
proliferating cell nuclear antigen |
|
increases expression |
EXP |
2 |
132,075,022 |
132,078,916 |
RGD:6480464 |
CTD |
| G |
Por |
P450 (cytochrome) oxidoreductase |
|
decreases response to substance |
EXP |
5 |
136,165,084 |
136,211,195 |
RGD:6480464 |
CTD |
| G |
Ptma |
prothymosin alpha |
|
increases expression |
ISO |
1 |
88,423,311 |
88,427,273 |
RGD:6480464 |
CTD |
| G |
Pvr |
poliovirus receptor |
|
increases expression |
ISO |
7 |
20,488,927 |
20,506,492 |
RGD:6480464 |
CTD |
| G |
Pygl |
liver glycogen phosphorylase |
|
decreases expression |
ISO |
12 |
71,291,802 |
71,328,670 |
RGD:6480464 |
CTD |
| G |
Rela |
v-rel reticuloendotheliosis viral oncogene homolog A (avian) |
|
multiple interactions |
ISO |
19 |
5,637,490 |
5,648,130 |
RGD:6480464 |
CTD |
| G |
S100a8 |
S100 calcium binding protein A8 (calgranulin A) |
|
increases expression |
ISO |
3 |
90,472,993 |
90,473,956 |
RGD:6480464 |
CTD |
| G |
S100a9 |
S100 calcium binding protein A9 (calgranulin B) |
|
increases expression |
ISO |
3 |
90,496,555 |
90,499,613 |
RGD:6480464 |
CTD |
| G |
Scn5a |
sodium channel, voltage-gated, type V, alpha |
|
decreases activity |
ISO |
9 |
119,392,529 |
119,488,134 |
RGD:6480464 |
CTD |
| G |
Slc2a1 |
solute carrier family 2 (facilitated glucose transporter), member 1 |
|
increases expression |
ISO |
4 |
118,781,350 |
118,809,935 |
RGD:6480464 |
CTD |
| G |
Tap1 |
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
|
increases expression |
ISO |
17 |
34,324,501 |
34,334,170 |
RGD:6480464 |
CTD |
| G |
Thrsp |
thyroid hormone responsive |
|
decreases expression |
ISO |
7 |
104,561,467 |
104,566,020 |
RGD:6480464 |
CTD |
| G |
Timp1 |
tissue inhibitor of metalloproteinase 1 |
|
increases expression |
ISO |
X |
20,447,292 |
20,451,863 |
RGD:6480464 |
CTD |
| G |
Tnfrsf1a |
tumor necrosis factor receptor superfamily, member 1a |
|
increases expression |
ISO |
6 |
125,299,741 |
125,312,501 |
RGD:6480464 |
CTD |
| G |
Trp53 |
transformation related protein 53 |
|
increases expression |
ISO |
11 |
69,393,861 |
69,405,375 |
RGD:6480464 |
CTD |
| G |
Trp53 |
transformation related protein 53 |
|
increases phosphorylation |
ISO |
11 |
69,393,861 |
69,405,375 |
RGD:6480464 |
CTD |
| G |
Trp53 |
transformation related protein 53 |
|
increases phosphorylation |
ISO |
11 |
69,393,861 |
69,405,375 |
RGD:6480464 |
CTD |
| G |
Ttr |
transthyretin |
|
decreases expression |
ISO |
18 |
20,823,751 |
20,832,827 |
RGD:6480464 |
CTD |
| G |
Txn1 |
thioredoxin 1 |
|
increases expression |
ISO |
4 |
57,956,245 |
57,969,283 |
RGD:6480464 |
CTD |
| G |
Txnrd1 |
thioredoxin reductase 1 |
|
decreases expression |
ISO |
10 |
82,296,696 |
82,360,469 |
RGD:6480464 |
CTD |
| G |
Vnn1 |
vanin 1 |
|
increases expression |
ISO |
10 |
23,614,494 |
23,625,149 |
RGD:6480464 |
CTD |
| G |
Zfand5 |
zinc finger, AN1-type domain 5 |
|
increases expression |
EXP |
19 |
21,346,768 |
21,356,779 |
RGD:6480464 |
CTD |
Term paths to the root
|