ONTOLOGY REPORT - ANNOTATIONS

Term:budesonide
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Accession:CHEBI:3207 term browser browse the term
Definition:A glucocorticoid steroid having a highly oxygenated pregna-1,4-diene structure. It is used mainly in the treatment of asthma and non-infectious rhinitis and for treatment and prevention of nasal polyposis.
Synonyms:exact_synonym: 11beta,21-dihydroxy-16alpha,17alpha-(butane-1,1-diyldioxy)pregna-1,4-diene-3,20-dione
 related_synonym: (11beta,16alpha)-16,17-(Butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione;   C25H34O6;   InChI=1S/C25H34O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h8-10,16-18,20-22,26,28H,4-7,11-13H2,1-3H3/t16-,17-,18-,20+,21?,22+,23-,24-,25+/m0/s1;   InChIKey=VOVIALXJUBGFJZ-KWVAZRHASA-N;   [H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])C[C@H]2OC(CCC)O[C@@]12C(=O)CO
 xref_casrn: 51333-22-3
 xref: ChEMBL:413314 "ChEMBL COMPOUND";   ChemIDplus:51333-22-3 "CAS Registry Number";   CiteXplore:21616561 "PubMed citation";   DrugBank:DB01222 "DrugBank";   KEGG DRUG:51333-22-3 "CAS Registry Number";   KEGG DRUG:D00246 "KEGG DRUG"
 xref_mesh: MESH:D019819
 xref: Patent:DE2323215 "Patent";   Patent:US3929768 "Patent";   Wikipedia:Budesonide "Wikipedia"

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budesonide term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link increases expression ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Adrb2 adrenoceptor beta 2, surface GBrowse link increases expression ISO 18 58,174,958 58,177,000 RGD:6480464 CTD
G Ar androgen receptor GBrowse link multiple interactions ISO X 85,949,507 86,119,199 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link decreases expression ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link decreases expression ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Ccl17 chemokine (C-C motif) ligand 17 GBrowse link decreases expression ISO 19 10,641,376 10,642,827 RGD:6480464 CTD
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link decreases expression ISO 10 70,256,263 70,258,061 RGD:6480464 CTD
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link multiple interactions EXP 10 70,256,263 70,258,061 RGD:6480464 CTD
G Ccl3 chemokine (C-C motif) ligand 3 GBrowse link increases expression ISO 10 71,744,559 71,746,109 RGD:6480464 CTD
G Ccl4 chemokine (C-C motif) ligand 4 GBrowse link increases expression ISO 10 71,759,643 71,761,115 RGD:6480464 CTD
G Ccnb2 cyclin B2 GBrowse link decreases expression ISO 8 74,892,108 74,906,181 RGD:6480464 CTD
G Ccne1 cyclin E1 GBrowse link decreases expression ISO 1 90,568,189 90,577,426 RGD:6480464 CTD
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link multiple interactions ISO 20 7,376,325 7,386,778 RGD:6480464 CTD
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link increases expression ISO 20 7,376,325 7,386,778 RGD:6480464 CTD
G Cdkn1b cyclin-dependent kinase inhibitor 1B GBrowse link multiple interactions ISO 4 171,841,705 171,846,506 RGD:6480464 CTD
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) GBrowse link decreases secretion ISO 10 39,665,850 39,667,831 RGD:6480464 CTD
G Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) GBrowse link multiple interactions EXP 14 18,690,339 18,692,118 RGD:6480464 CTD
G Cxcl2 chemokine (C-X-C motif) ligand 2 GBrowse link multiple interactions EXP 14 18,677,129 18,679,175 RGD:6480464 CTD
G Cxcl3 chemokine (C-X-C motif) ligand 3 GBrowse link multiple interactions EXP 14 18,767,306 18,787,340 RGD:6480464 CTD
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 GBrowse link decreases expression EXP 12 9,517,016 9,541,000 RGD:6480464 CTD
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 GBrowse link increases expression EXP 12 17,164,384 17,204,589 RGD:6480464 CTD
G Gcg glucagon GBrowse link decreases expression EXP 3 44,433,180 44,438,004 RGD:6480464 CTD
G Gcg glucagon GBrowse link multiple interactions EXP 3 44,433,180 44,438,004 RGD:6480464 CTD
G Ifng interferon gamma GBrowse link decreases secretion ISO 7 57,621,756 57,625,792 RGD:6480464 CTD
G Ifng interferon gamma GBrowse link multiple interactions ISO 7 57,621,756 57,625,792 RGD:6480464 CTD
G Igf2 insulin-like growth factor 2 GBrowse link multiple interactions ISO 1 202,906,624 202,915,231 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link multiple interactions ISO 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link decreases secretion ISO 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link multiple interactions ISO 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link multiple interactions EXP 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il4 interleukin 4 GBrowse link decreases expression ISO 10 39,074,582 39,080,134 RGD:6480464 CTD
G Il4 interleukin 4 GBrowse link decreases expression ISO 10 39,074,582 39,080,134 RGD:6480464 CTD
G Il4r interleukin 4 receptor GBrowse link decreases expression ISO 1 184,612,903 184,637,863 RGD:6480464 CTD
G Il5 interleukin 5 GBrowse link decreases expression ISO 10 39,177,786 39,180,657 RGD:6480464 CTD
G Il5 interleukin 5 GBrowse link decreases expression ISO 10 39,177,786 39,180,657 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link multiple interactions EXP 4 456,799 461,376 RGD:6480464 CTD
G Jun jun proto-oncogene GBrowse link decreases expression EXP 5 115,358,166 115,361,259 RGD:6480464 CTD
G Mmp9 matrix metallopeptidase 9 GBrowse link multiple interactions EXP 3 155,985,473 155,993,433 RGD:6480464 CTD
G Mpo myeloperoxidase GBrowse link multiple interactions EXP 10 76,085,872 76,097,012 RGD:6480464 CTD
G Mt2A metallothionein 2A GBrowse link increases expression ISO 19 11,267,811 11,268,585 RGD:6480464 CTD
G Mt2A metallothionein 2A GBrowse link multiple interactions ISO 19 11,267,811 11,268,585 RGD:6480464 CTD
G Myc myelocytomatosis oncogene GBrowse link multiple interactions ISO 7 98,953,142 98,958,060 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link decreases expression ISO 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link multiple interactions EXP 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 GBrowse link multiple interactions ISO 18 32,371,496 32,459,145 RGD:6480464 CTD
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 GBrowse link decreases expression ISO 18 32,371,496 32,459,145 RGD:6480464 CTD
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 GBrowse link increases activity ISO 18 32,371,496 32,459,145 RGD:6480464 CTD
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 GBrowse link increases activity ISO 18 32,371,496 32,459,145 RGD:6480464 CTD
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 GBrowse link multiple interactions ISO 18 32,371,496 32,459,145 RGD:6480464 CTD
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 GBrowse link increases activity ISO 18 32,371,496 32,459,145 RGD:6480464 CTD
G Pcna proliferating cell nuclear antigen GBrowse link decreases expression ISO 3 120,008,715 120,012,589 RGD:6480464 CTD
G Ppara peroxisome proliferator activated receptor alpha GBrowse link multiple interactions ISO 7 123,729,774 123,807,090 RGD:6480464 CTD
G Ptges2 prostaglandin E synthase 2 GBrowse link multiple interactions EXP 3 11,521,214 11,528,395 RGD:6480464 CTD
G Ptgs1 prostaglandin-endoperoxide synthase 1 GBrowse link multiple interactions EXP 3 15,343,832 15,365,412 RGD:6480464 CTD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link multiple interactions ISO 13 64,427,288 64,432,978 RGD:6480464 CTD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link multiple interactions EXP 13 64,427,288 64,432,978 RGD:6480464 CTD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link multiple interactions EXP 1 208,262,669 208,273,148 RGD:6480464 CTD
G Rnase17 ribonuclease 17 GBrowse link decreases expression ISO 15 27,259,616 27,260,083 RGD:6480464 CTD
G Sele selectin E GBrowse link multiple interactions EXP 13 79,813,455 79,822,845 RGD:6480464 CTD
G Sell selectin L GBrowse link multiple interactions EXP 13 79,827,342 79,845,296 RGD:6480464 CTD
G Selp selectin P GBrowse link multiple interactions EXP 13 79,886,614 79,922,180 RGD:6480464 CTD
G Slc22a3 solute carrier family 22 (extraneuronal monoamine transporter), member 3 GBrowse link multiple interactions ISO 1 42,690,158 42,781,895 RGD:6480464 CTD
G Slco1b3 solute carrier organic anion transporter family, member 1b3 GBrowse link multiple interactions ISO 4 179,045,586 179,118,680 RGD:6480464 CTD
G Slco2b1 solute carrier organic anion transporter family, member 2b1 GBrowse link multiple interactions ISO 1 156,992,492 157,028,887 RGD:6480464 CTD
G Spp1 secreted phosphoprotein 1 increases expression ISO RGD:6480464 CTD
G Tgm2 transglutaminase 2, C polypeptide GBrowse link increases expression ISO 3 148,832,866 148,862,385 RGD:6480464 CTD
G Timp1 TIMP metallopeptidase inhibitor 1 GBrowse link multiple interactions EXP X 12,542,496 12,547,094 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link decreases expression ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link decreases secretion ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link decreases expression ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Vcam1 vascular cell adhesion molecule 1 GBrowse link multiple interactions EXP 2 212,277,654 212,297,376 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link decreases expression ISO 9 10,520,730 10,536,071 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link multiple interactions ISO 9 10,520,730 10,536,071 RGD:6480464 CTD
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 492574
    role 482262
      application 245197
        anti-inflammatory agent 34323
          anti-inflammatory drug 21950
            budesonide 75
Path 2
Term Annotations click to browse term
  CHEBI ontology 492574
    subatomic particle 491537
      composite particle 491537
        hadron 491537
          baryon 491537
            nucleon 491537
              atomic nucleus 491537
                atom 491537
                  main group element atom 461203
                    p-block element atom 458699
                      carbon group element atom 410677
                        carbon atom 407233
                          organic molecular entity 407226
                            organic group 167766
                              organic divalent group 166601
                                organodiyl group 166601
                                  carbonyl group 166291
                                    carbonyl compound 166291
                                      ketone 31433
                                        oxo steroid 13480
                                          3-oxo steroid 11985
                                            budesonide 75
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