ampicillin - Ontology Report - Rat Genome Database

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Keyword

ONTOLOGY REPORT - ANNOTATIONS

Term:	ampicillin	go back to main search page
Accession:	CHEBI:28971	browse the term
Definition:	A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-phenylacetamido group.
Synonyms:	exact_synonym:	6beta-[(2R)-2-amino-2-phenylacetamido]-2,2-dimethylpenam-3alpha-carboxylic acid
	related_synonym:	(2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID; (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 6-(D-(2-amino-2-phenylacetamido))-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid; ABPC; AMP; AP; C16H19N3O4S; D-(-)-6-(alpha-aminophenylacetamido)penicillanic acid; D-(-)-ampicillin; InChI=1S/C16H19N3O4S/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23)/t9-,10-,11+,14-/m1/s1; InChIKey=AVKUERGKIZMTKX-NJBDSQKTSA-N; [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)c1ccccc1)C(O)=O; aminobenzylpenicillin; ampicilina; ampicillin acid; ampicillin anhydrous; ampicilline; ampicillinum
	alt_id:	CHEBI:22536; CHEBI:2683; CHEBI:40648; CHEBI:45042
	xref_casrn:	69-53-4
	xref:	Beilstein:4300240 "Beilstein Registry Number"; ChEMBL:405519 "ChEMBL COMPOUND"; ChemIDplus:69-53-4 "CAS Registry Number"; CiteXplore:10930630 "PubMed citation"; CiteXplore:12569987 "PubMed citation"; CiteXplore:12833570 "PubMed citation"; CiteXplore:16033609 "PubMed citation"; CiteXplore:2083978 "PubMed citation"; CiteXplore:6176550 "PubMed citation"; DrugBank:DB00415 "DrugBank"; KEGG COMPOUND:C06574 "KEGG COMPOUND"; KEGG DRUG:D00204 "KEGG DRUG"
	xref_mesh:	MESH:D000667
	xref:	PDB:1H8S "PDB"; PDBeChem:AIC "PDBeChem"; Patent:GB902703 "Patent"; Patent:US2985648 "Patent"; Patent:US3157640 "Patent"; Reaxys:4300240 "Reaxys Registry Number"; Wikipedia:Ampicillin "Wikipedia"
	cyclic_relationship:	is_conjugate_acid_of CHEBI:50658

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ampicillin
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Abcc3	ATP-binding cassette, subfamily C (CFTR/MRP), member 3		decreases expression	ISO	10	82,986,552	83,030,799	RGD:6480464	CTD
G	Abcc4	ATP-binding cassette, subfamily C (CFTR/MRP), member 4		increases transport	ISO	15	103,384,848	103,611,238	RGD:6480464	CTD
G	Agpat9	1-acylglycerol-3-phosphate O-acyltransferase 9		decreases expression	ISO	14	9,998,566	10,050,154	RGD:6480464	CTD
G	Akr1b10	aldo-keto reductase family 1, member B10 (aldose reductase)		decreases expression	ISO	4	61,755,871	61,771,264	RGD:6480464	CTD
G	Akr1c2	aldo-keto reductase family 1, member C2		decreases expression	ISO	17	77,034,737	77,081,406	RGD:6480464	CTD
G	Amot	angiomotin		increases expression	ISO	X	33,018,434	33,062,515	RGD:6480464	CTD
G	Ankrd1	ankyrin repeat domain 1		increases expression	ISO	1	240,316,123	240,324,804	RGD:6480464	CTD
G	Aqp3	aquaporin 3		decreases expression	ISO	5	58,501,642	58,507,159	RGD:6480464	CTD
G	Arg1	arginase, liver		increases expression	ISO	1	20,998,894	21,011,275	RGD:6480464	CTD
G	Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha		increases expression	ISO	10	109,967,771	109,971,260	RGD:6480464	CTD
G	Arrdc3	arrestin domain containing 3		decreases expression	ISO				RGD:6480464	CTD
G	Asns	asparagine synthetase (glutamine-hydrolyzing)		decreases expression	ISO	4	32,758,866	32,776,220	RGD:6480464	CTD
G	Bax	Bcl2-associated X protein		increases response to substance	ISO	1	95,933,023	95,938,176	RGD:6480464	CTD
G	Calr	calreticulin		increases expression	ISO	19	24,964,775	24,969,670	RGD:6480464	CTD
G	Car9	carbonic anhydrase 9		increases expression	ISO	5	59,986,413	59,993,015	RGD:6480464	CTD
G	Ccpg1	cell cycle progression 1		decreases expression	ISO	8	77,724,315	77,768,060	RGD:6480464	CTD
G	Chst15	carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15		increases expression	ISO	1	191,708,603	191,737,958	RGD:6480464	CTD
G	Ckb	creatine kinase, brain		increases expression	ISO	6	136,452,215	136,455,122	RGD:6480464	CTD
G	Clgn	calmegin		decreases expression	ISO	19	26,404,126	26,436,081	RGD:6480464	CTD
G	Clic3	chloride intracellular channel 3		increases expression	ISO	3	3,622,894	3,624,805	RGD:6480464	CTD
G	Cp	ceruloplasmin (ferroxidase)		increases expression	ISO	2	105,086,278	105,135,367	RGD:6480464	CTD
G	Creb3l3	cAMP responsive element binding protein 3-like 3		decreases expression	ISO	7	10,106,525	10,114,960	RGD:6480464	CTD
G	Csta	cystatin A (stefin A)		decreases expression	ISO	11	66,456,248	66,467,253	RGD:6480464	CTD
G	Cyp1a1	cytochrome P450, family 1, subfamily a, polypeptide 1		decreases expression	ISO	8	61,462,207	61,468,237	RGD:6480464	CTD
G	Cyp24a1	cytochrome P450, family 24, subfamily a, polypeptide 1		decreases expression	ISO	3	161,542,131	161,553,801	RGD:6480464	CTD
G	Cyr61	cysteine-rich, angiogenic inducer, 61		increases expression	ISO	2	243,824,303	243,827,262	RGD:6480464	CTD
G	Dkk1	dickkopf WNT signaling pathway inhibitor 1		increases expression	ISO	1	234,392,743	234,396,426	RGD:6480464	CTD
G	Dusp1	dual specificity phosphatase 1		increases expression	ISO	10	16,942,913	16,945,696	RGD:6480464	CTD
G	Dusp7	dual specificity phosphatase 7		increases expression	ISO	8	111,510,358	111,515,989	RGD:6480464	CTD
G	Edn1	endothelin 1		increases expression	ISO	17	28,303,886	28,309,775	RGD:6480464	CTD
G	Esm1	endothelial cell-specific molecule 1		decreases expression	ISO	2	44,626,010	44,634,748	RGD:6480464	CTD
G	Filip1l	filamin A interacting protein 1-like		increases expression	ISO	11	43,788,676	43,859,932	RGD:6480464	CTD
G	Fxyd1	FXYD domain-containing ion transport regulator 1		increases expression	ISO	1	86,095,551	86,098,079	RGD:6480464	CTD
G	Gclc	glutamate-cysteine ligase, catalytic subunit		decreases expression	ISO	8	82,724,429	82,762,848	RGD:6480464	CTD
G	Gclm	glutamate cysteine ligase, modifier subunit		increases expression	ISO	2	218,895,434	218,915,491	RGD:6480464	CTD
G	Gclm	glutamate cysteine ligase, modifier subunit		decreases expression	ISO	2	218,895,434	218,915,491	RGD:6480464	CTD
G	Hoxd1	homeo box D1		increases expression	ISO	3	57,377,839	57,379,978	RGD:6480464	CTD
G	Ifrd1	interferon-related developmental regulator 1		decreases expression	ISO				RGD:6480464	CTD
G	Igfbp3	insulin-like growth factor binding protein 3		increases expression	ISO	14	87,959,153	87,967,085	RGD:6480464	CTD
G	Il1b	interleukin 1 beta		multiple interactions	EXP	3	116,964,422	116,970,867	RGD:6480464	CTD
G	Jdp2	Jun dimerization protein 2		decreases expression	ISO	6	109,708,745	109,740,375	RGD:6480464	CTD
G	Jund	jun D proto-oncogene		increases expression	ISO	16	19,239,694	19,241,529	RGD:6480464	CTD
G	Lox	lysyl oxidase		increases expression	ISO	18	47,896,674	47,970,829	RGD:6480464	CTD
G	Lppr1	lipid phosphate phosphatase-related protein type 1		increases expression	ISO	5	65,982,029	66,115,218	RGD:6480464	CTD
G	Maz	MYC-associated zinc finger protein (purine-binding transcription factor)		increases expression	ISO	1	186,201,083	186,204,364	RGD:6480464	CTD
G	Mpo	myeloperoxidase		multiple interactions	EXP	10	76,085,872	76,097,012	RGD:6480464	CTD
G	Mpo	myeloperoxidase		multiple interactions	EXP	10	76,085,872	76,097,012	RGD:6480464	CTD
G	Mpo	myeloperoxidase		multiple interactions	EXP	10	76,085,872	76,097,012	RGD:6480464	CTD
G	Mpo	myeloperoxidase		multiple interactions	EXP	10	76,085,872	76,097,012	RGD:6480464	CTD
G	Mtss1l	metastasis suppressor 1-like		increases expression	ISO	19	40,640,947	40,661,240	RGD:6480464	CTD
G	Nos2	nitric oxide synthase 2, inducible		multiple interactions	EXP	10	65,036,884	65,072,453	RGD:6480464	CTD
G	Nos2	nitric oxide synthase 2, inducible		multiple interactions	EXP	10	65,036,884	65,072,453	RGD:6480464	CTD
G	Nos2	nitric oxide synthase 2, inducible		multiple interactions	EXP	10	65,036,884	65,072,453	RGD:6480464	CTD
G	Nos2	nitric oxide synthase 2, inducible		multiple interactions	EXP	10	65,036,884	65,072,453	RGD:6480464	CTD
G	Nos2	nitric oxide synthase 2, inducible		multiple interactions	EXP	10	65,036,884	65,072,453	RGD:6480464	CTD
G	Nos2	nitric oxide synthase 2, inducible		multiple interactions	EXP	10	65,036,884	65,072,453	RGD:6480464	CTD
G	Nos2	nitric oxide synthase 2, inducible		multiple interactions	EXP	10	65,036,884	65,072,453	RGD:6480464	CTD
G	Nos2	nitric oxide synthase 2, inducible		multiple interactions	EXP	10	65,036,884	65,072,453	RGD:6480464	CTD
G	Nqo1	NAD(P)H dehydrogenase, quinone 1		increases expression	ISO	19	37,251,147	37,266,040	RGD:6480464	CTD
G	Pa2g4	proliferation-associated 2G4		increases expression	ISO	7	1,846,628	1,854,096	RGD:6480464	CTD
G	Pabpc1l	poly(A) binding protein, cytoplasmic 1-like		decreases expression	ISO	3	154,959,889	154,992,338	RGD:6480464	CTD
G	Pdp2	pyruvate dehyrogenase phosphatase catalytic subunit 2		increases expression	ISO	19	307,961	312,004	RGD:6480464	CTD
G	Pfkfb3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3		increases expression	ISO	17	78,241,182	78,268,272	RGD:6480464	CTD
G	Pgc	progastricsin (pepsinogen C)		increases expression	ISO	9	8,723,620	8,731,837	RGD:6480464	CTD
G	Pgd	phosphogluconate dehydrogenase		decreases activity	EXP				RGD:6480464	CTD
G	Pir	pirin (iron-binding nuclear protein)		increases expression	ISO	X	50,864,981	50,974,861	RGD:6480464	CTD
G	Pkm	pyruvate kinase, muscle		increases expression	ISO	8	63,486,492	63,508,016	RGD:6480464	CTD
G	Pon1	paraoxonase 1		decreases activity	ISO	4	29,936,314	29,964,821	RGD:6480464	CTD
G	Pon1	paraoxonase 1		decreases activity	ISO	4	29,936,314	29,964,821	RGD:6480464	CTD
G	Ptgr1	prostaglandin reductase 1		decreases expression	ISO	5	77,010,809	77,029,326	RGD:6480464	CTD
G	Ptgs2	prostaglandin-endoperoxide synthase 2		multiple interactions	EXP	13	64,427,288	64,432,978	RGD:6480464	CTD
G	Ptgs2	prostaglandin-endoperoxide synthase 2		multiple interactions	EXP	13	64,427,288	64,432,978	RGD:6480464	CTD
G	Ptms	parathymosin		increases expression	ISO	4	161,041,242	161,045,145	RGD:6480464	CTD
G	Rgcc	regulator of cell cycle		increases expression	ISO	15	60,451,831	60,452,229	RGD:6480464	CTD
G	Sgk2	serum/glucocorticoid regulated kinase 2		decreases expression	ISO	3	153,849,825	153,890,111	RGD:6480464	CTD
G	Slc1a2	solute carrier family 1 (glial high affinity glutamate transporter), member 2		increases expression	ISO	3	87,870,558	87,992,401	RGD:6480464	CTD
G	Slc22a15	solute carrier family 22, member 15		decreases expression	ISO	2	196,953,291	197,013,763	RGD:6480464	CTD
G	Slc2a3	solute carrier family 2 (facilitated glucose transporter), member 3		increases expression	ISO	4	159,210,116	159,221,169	RGD:6480464	CTD
G	Slc6a14	solute carrier family 6 (amino acid transporter), member 14		increases expression	ISO	X	12,048,993	12,072,434	RGD:6480464	CTD
G	Slc6a8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8		increases expression	ISO	X	159,570,789	159,580,093	RGD:6480464	CTD
G	Slc7a11	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11		decreases expression	ISO	2	139,241,142	139,317,101	RGD:6480464	CTD
G	Smim14	small integral membrane protein 14		decreases expression	ISO	14	45,477,213	45,520,785	RGD:6480464	CTD
G	Srxn1	sulfiredoxin 1		decreases expression	ISO	3	142,457,352	142,462,725	RGD:6480464	CTD
G	Tagln	transgelin		increases expression	ISO	8	48,902,208	48,907,682	RGD:6480464	CTD
G	Timp1	TIMP metallopeptidase inhibitor 1		decreases expression	ISO	X	12,542,496	12,547,094	RGD:6480464	CTD
G	Tnf	tumor necrosis factor		multiple interactions	EXP	20	3,661,000	3,663,618	RGD:6480464	CTD
G	Tpm4	tropomyosin 4		increases expression	ISO	16	18,108,914	18,122,956	RGD:6480464	CTD
G	Trim16	tripartite motif-containing 16		increases expression	ISO	10	48,987,004	49,009,696	RGD:6480464	CTD
G	Ttyh3	tweety homolog 3 (Drosophila)		increases expression	ISO	12	14,463,541	14,491,939	RGD:6480464	CTD
G	Tube1	tubulin, epsilon 1		decreases expression	ISO	20	43,280,097	43,298,415	RGD:6480464	CTD
G	Vegfa	vascular endothelial growth factor A		multiple interactions	EXP	9	10,520,730	10,536,071	RGD:6480464	CTD
G	Vldlr	very low density lipoprotein receptor		decreases expression	ISO	1	230,666,736	230,697,748	RGD:6480464	CTD

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	501881
role	491510
biological role	489686
antimicrobial agent	46038
antibacterial agent	15667
antibacterial drug	4095
ampicillin	92
ampicillin trihydrate	0
ampicilloyl group +	0
ampicilloyl-butylamine	0
bacampicillin +	0
epicillin	0
pivampicillin	0
sultamicillin +	0
talampicillin +	0
Path 2
Term	Annotations
CHEBI ontology	501881
subatomic particle	500845
composite particle	500845
hadron	500845
baryon	500845
nucleon	500845
atomic nucleus	500845
atom	500845
main group element atom	470301
p-block element atom	467779
carbon group element atom	419149
carbon atom	415667
organic molecular entity	415660
organic group	171184
organic divalent group	169999
organodiyl group	169999
carbonyl group	169689
carbonyl compound	169689
pseudoketone	13104
cyclic pseudoketone	12715
lactam	1879
beta-lactam	687
beta-lactam antibiotic	687
penams	131
penicillanic acids	131
penicillanic acid	130
6-aminopenicillanic acid	130
penicillin	130
ampicillin	92
ampicillin trihydrate	0
ampicilloyl group +	0
ampicilloyl-butylamine	0
bacampicillin +	0
epicillin	0
pivampicillin	0
sultamicillin +	0
talampicillin +	0