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Term:leukotriene D4
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Accession:CHEBI:28666 term browser browse the term
Definition:A leukotriene that has formula C25H40N2O6S.
Synonyms:exact_synonym: S-{(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl}-L-cysteinylglycine
 related_synonym: (R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-L-cysteinyl)glycine;   5S-hydroxy-6R-(S-cysteinylglycinyl)-7E,9E,11E,14Z-eicosatetraenoic acid;   C25H40N2O6S;   CCCCC\\C=C/C\\C=C/C=C/C=C/[C@@H](SC[C@H](N)C(=O)NCC(O)=O)[C@@H](O)CCCC(O)=O;   InChI=1S/C25H40N2O6S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-22(21(28)15-14-17-23(29)30)34-19-20(26)25(33)27-18-24(31)32/h6-7,9-13,16,20-22,28H,2-5,8,14-15,17-19,26H2,1H3,(H,27,33)(H,29,30)(H,31,32)/b7-6-,10-9-,12-11+,16-13+/t20-,21-,22+/m0/s1;   InChIKey=YEESKJGWJFYOOK-IJHYULJSSA-N;   LTD4
 alt_id: CHEBI:25026;   CHEBI:6423
 xref_casrn: 73836-78-9
 xref: ChEMBL:154759 "ChEMBL COMPOUND";   ChemIDplus:73836-78-9 "CAS Registry Number";   LIPID MAPS:LMFA03020006 "LIPID MAPS instance"
 xref_mesh: MESH:D017998
 cyclic_relationship: is_conjugate_acid_of CHEBI:63166

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leukotriene D4 term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Alox5 arachidonate 5-lipoxygenase GBrowse link increases abundance ISO 4 152,610,283 152,657,891 RGD:6480464 CTD
G Alox5 arachidonate 5-lipoxygenase GBrowse link multiple interactions ISO 4 152,610,283 152,657,891 RGD:6480464 CTD
G Alox5 arachidonate 5-lipoxygenase GBrowse link multiple interactions ISO 4 152,610,283 152,657,891 RGD:6480464 CTD
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) GBrowse link multiple interactions ISO 10 39,665,850 39,667,831 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link increases response to substance ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link affects binding ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link increases activity ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link affects binding ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link affects binding ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link affects binding ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 94,802,078 94,803,097 RGD:6480464 CTD
G Cysltr2 cysteinyl leukotriene receptor 2 GBrowse link multiple interactions ISO 15 53,647,500 53,648,429 RGD:6480464 CTD
G Cysltr2 cysteinyl leukotriene receptor 2 GBrowse link multiple interactions ISO 15 53,647,500 53,648,429 RGD:6480464 CTD
G Cysltr2 cysteinyl leukotriene receptor 2 GBrowse link multiple interactions ISO 15 53,647,500 53,648,429 RGD:6480464 CTD
G Cysltr2 cysteinyl leukotriene receptor 2 GBrowse link multiple interactions ISO 15 53,647,500 53,648,429 RGD:6480464 CTD
G Fas Fas (TNF receptor superfamily, member 6) GBrowse link decreases expression ISO 1 238,259,443 238,274,745 RGD:6480464 CTD
G Gpr17 G protein-coupled receptor 17 GBrowse link increases activity ISO 18 24,374,253 24,375,272 RGD:6480464 CTD
G Gpr17 G protein-coupled receptor 17 GBrowse link multiple interactions ISO 18 24,374,253 24,375,272 RGD:6480464 CTD
G Icam1 intercellular adhesion molecule 1 GBrowse link multiple interactions ISO 8 20,040,177 20,051,939 RGD:6480464 CTD
G Il12a interleukin 12A GBrowse link multiple interactions ISO 2 158,710,261 158,717,689 RGD:6480464 CTD
G Il12b interleukin 12B GBrowse link multiple interactions ISO 10 29,558,955 29,568,331 RGD:6480464 CTD
G Il13 interleukin 13 GBrowse link increases abundance EXP 10 39,093,512 39,096,069 RGD:6480464 CTD
G Il13 interleukin 13 GBrowse link multiple interactions EXP 10 39,093,512 39,096,069 RGD:6480464 CTD
G Il5 interleukin 5 GBrowse link multiple interactions ISO 10 39,177,786 39,180,657 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link multiple interactions ISO 4 456,799 461,376 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link multiple interactions ISO 4 456,799 461,376 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link increases secretion ISO 4 456,799 461,376 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link increases phosphorylation ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link increases phosphorylation ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mgst1 microsomal glutathione S-transferase 1 GBrowse link decreases activity EXP 4 175,248,654 175,263,881 RGD:6480464 CTD
G Mmp9 matrix metallopeptidase 9 GBrowse link multiple interactions ISO 3 155,985,473 155,993,433 RGD:6480464 CTD
G Mmp9 matrix metallopeptidase 9 GBrowse link increases expression ISO 3 155,985,473 155,993,433 RGD:6480464 CTD
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions EXP RGD:6480464 CTD
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming increases expression EXP RGD:6480464 CTD
G Pdgfrb platelet derived growth factor receptor, beta polypeptide GBrowse link multiple interactions ISO 18 57,014,475 57,053,581 RGD:6480464 CTD
G Selp selectin P GBrowse link increases expression ISO 13 79,886,614 79,922,180 RGD:6480464 CTD
G Src v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) GBrowse link multiple interactions ISO 3 148,157,256 148,170,524 RGD:6480464 CTD
G Tgfb1 transforming growth factor, beta 1 GBrowse link multiple interactions ISO 1 80,894,705 80,911,020 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link increases secretion ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 492574
    chemical entity 492574
      atom 491537
        nonmetal atom 450591
          carbon atom 407233
            organic molecular entity 407226
              fatty acid derivative 1175
                icosanoid 1175
                  leukotriene 255
                    leukotriene D4 100
Path 2
Term Annotations click to browse term
  CHEBI ontology 492574
    subatomic particle 491537
      composite particle 491537
        hadron 491537
          baryon 491537
            nucleon 491537
              atomic nucleus 491537
                atom 491537
                  main group element atom 461203
                    p-block element atom 458699
                      carbon group element atom 410677
                        carbon atom 407233
                          organic molecular entity 407226
                            organic group 167766
                              organic divalent group 166601
                                organodiyl group 166601
                                  carbonyl group 166291
                                    carbonyl compound 166291
                                      carboxylic acid 121484
                                        monocarboxylic acid 70508
                                          fatty acid 25073
                                            unsaturated fatty acid 1491
                                              polyunsaturated fatty acid 1144
                                                icosatetraenoic acid 728
                                                  icosa-7,9,11,14-tetraenoic acid 190
                                                    leukotriene D4 100
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