caffeine - Ontology Report - Rat Genome Database

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ONTOLOGY REPORT - ANNOTATIONS

Term:	caffeine	go back to main search page
Accession:	CHEBI:27732	browse the term
Definition:	A trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7.
Synonyms:	exact_synonym:	1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione
	related_synonym:	1,3,7-trimethyl-2,6-dioxopurine; 1,3,7-trimethylpurine-2,6-dione; 1,3,7-trimethylxanthine; 1-methyltheobromine; 3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion; 7-methyltheophylline; C8H10N4O2; Cn1cnc2n(C)c(=O)n(C)c(=O)c12; Coffein; InChI=1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3; InChIKey=RYYVLZVUVIJVGH-UHFFFAOYSA-N; Koffein; Thein; anhydrous caffeine; cafeina; cafeine; guaranine; mateina; methyltheobromine; teina; theine
	alt_id:	CHEBI:22982; CHEBI:3295; CHEBI:41472
	xref_casrn:	58-08-2
	xref:	Beilstein:17705 "Beilstein Registry Number"; ChEMBL:116485 "ChEMBL COMPOUND"; ChemIDplus:58-08-2 "CAS Registry Number"; CiteXplore:10510174 "PubMed citation"; CiteXplore:10803761 "PubMed citation"; CiteXplore:10884512 "PubMed citation"; CiteXplore:10983026 "PubMed citation"; CiteXplore:11022879 "PubMed citation"; CiteXplore:11209966 "PubMed citation"; CiteXplore:11410911 "PubMed citation"; CiteXplore:11431501 "PubMed citation"; CiteXplore:11815511 "PubMed citation"; CiteXplore:11949272 "PubMed citation"; CiteXplore:12574990 "PubMed citation"; CiteXplore:12915014 "PubMed citation"; CiteXplore:12943586 "PubMed citation"; CiteXplore:14521986 "PubMed citation"; CiteXplore:14607010 "PubMed citation"; CiteXplore:15257305 "PubMed citation"; CiteXplore:15681408 "PubMed citation"; CiteXplore:15718055 "PubMed citation"; CiteXplore:16143823 "PubMed citation"; CiteXplore:16644114 "PubMed citation"; CiteXplore:16709440 "PubMed citation"; CiteXplore:16805851 "PubMed citation"; CiteXplore:16856769 "PubMed citation"; CiteXplore:17132260 "PubMed citation"; CiteXplore:17387608 "PubMed citation"; CiteXplore:17508167 "PubMed citation"; CiteXplore:17932622 "PubMed citation"; CiteXplore:18258404 "PubMed citation"; CiteXplore:18421070 "PubMed citation"; CiteXplore:18625110 "PubMed citation"; CiteXplore:18647558 "PubMed citation"; CiteXplore:19007524 "PubMed citation"; CiteXplore:19047957 "PubMed citation"; CiteXplore:19084078 "PubMed citation"; CiteXplore:19088793 "PubMed citation"; CiteXplore:19879252 "PubMed citation"; CiteXplore:20470411 "PubMed citation"; CiteXplore:22770225 "PubMed citation"; CiteXplore:7441110 "PubMed citation"; CiteXplore:7689104 "PubMed citation"; CiteXplore:8332255 "PubMed citation"; CiteXplore:8347173 "PubMed citation"; CiteXplore:8679661 "PubMed citation"; CiteXplore:9063686 "PubMed citation"; CiteXplore:9067318 "PubMed citation"; CiteXplore:9132918 "PubMed citation"; CiteXplore:9218278 "PubMed citation"; DrugBank:DB00201 "DrugBank"; Gmelin:103040 "Gmelin Registry Number"; HMDB:HMDB01847 "HMDB"; KEGG COMPOUND:58-08-2 "CAS Registry Number"; KEGG COMPOUND:C07481 "KEGG COMPOUND"; KEGG DRUG:D00528 "KEGG DRUG"
	xref_mesh:	MESH:D002110
	xref:	MetaCyc:1-3-7-TRIMETHYLXANTHINE "MetaCyc"; NIST Chemistry WebBook:58-08-2 "CAS Registry Number"; PDBeChem:CFF "PDBeChem"; Reaxys:17705 "Reaxys Registry Number"; Wikipedia:Caffeine "Wikipedia"

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caffeine
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	ACAT2	acetyl-CoA acetyltransferase 2		decreases expression	EXP	6	160,182,989	160,200,087	RGD:6480464	CTD
G	ACIN1	apoptotic chromatin condensation inducer 1		increases expression	EXP	14	23,527,773	23,564,823	RGD:6480464	CTD
G	ACSL3	acyl-CoA synthetase long-chain family member 3		increases expression	EXP	2	223,725,732	223,808,119	RGD:6480464	CTD
G	ACTR1A	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)		multiple interactions	ISO	10	104,238,986	104,262,512	RGD:6480464	CTD
G	ADARB1	adenosine deaminase, RNA-specific, B1		decreases expression	ISO	21	46,494,493	46,646,478	RGD:6480464	CTD
G	ADCK3	aarF domain containing kinase 3		multiple interactions	ISO	1	227,127,938	227,175,246	RGD:6480464	CTD
G	ADCY7	adenylate cyclase 7		multiple interactions	ISO	16	50,321,823	50,352,043	RGD:6480464	CTD
G	ADIPOR2	adiponectin receptor 2		increases expression	ISO	12	1,800,247	1,897,845	RGD:6480464	CTD
G	ADORA1	adenosine A1 receptor		decreases activity	ISO	1	203,096,836	203,136,533	RGD:6480464	CTD
G	ADORA1	adenosine A1 receptor		decreases expression	ISO	1	203,096,836	203,136,533	RGD:6480464	CTD
G	ADORA1	adenosine A1 receptor		multiple interactions	ISO	1	203,096,836	203,136,533	RGD:6480464	CTD
G	ADORA1	adenosine A1 receptor		increases expression	ISO	1	203,096,836	203,136,533	RGD:6480464	CTD
G	ADORA1	adenosine A1 receptor		multiple interactions	ISO	1	203,096,836	203,136,533	RGD:6480464	CTD
G	ADORA1	adenosine A1 receptor		multiple interactions	ISO	1	203,096,836	203,136,533	RGD:6480464	CTD
G	ADORA1	adenosine A1 receptor		decreases activity	ISO	1	203,096,836	203,136,533	RGD:6480464	CTD
G	ADORA2A	adenosine A2a receptor		increases response to substance	EXP	22	24,823,530	24,838,325	RGD:6480464	CTD
G	ADORA2A	adenosine A2a receptor		affects response to substance	EXP	22	24,823,530	24,838,325	RGD:6480464	CTD
G	ADORA2A	adenosine A2a receptor		increases response to substance	EXP	22	24,823,530	24,838,325	RGD:6480464	CTD
G	ADORA2A	adenosine A2a receptor		increases response to substance	EXP	22	24,823,530	24,838,325	RGD:6480464	CTD
G	ADORA2A	adenosine A2a receptor		affects response to substance	ISO	22	24,823,530	24,838,325	RGD:6480464	CTD
G	ADORA2A	adenosine A2a receptor		increases response to substance	ISO	22	24,823,530	24,838,325	RGD:6480464	CTD
G	ADORA2A	adenosine A2a receptor		affects binding	ISO	22	24,823,530	24,838,325	RGD:6480464	CTD
G	ADORA2A	adenosine A2a receptor		multiple interactions	ISO	22	24,823,530	24,838,325	RGD:6480464	CTD
G	ADORA2A	adenosine A2a receptor		multiple interactions	ISO	22	24,823,530	24,838,325	RGD:6480464	CTD
G	ADORA2A	adenosine A2a receptor		multiple interactions	ISO	22	24,823,530	24,838,325	RGD:6480464	CTD
G	ADORA2A	adenosine A2a receptor		decreases expression	ISO	22	24,823,530	24,838,325	RGD:6480464	CTD
G	ADORA2B	adenosine A2b receptor		multiple interactions	EXP	17	15,848,231	15,879,210	RGD:6480464	CTD
G	AKR1A1	aldo-keto reductase family 1, member A1 (aldehyde reductase)		multiple interactions	ISO	1	46,016,455	46,035,723	RGD:6480464	CTD
G	AKT1	v-akt murine thymoma viral oncogene homolog 1		multiple interactions	EXP	14	105,235,686	105,262,080	RGD:6480464	CTD
G	AKT1	v-akt murine thymoma viral oncogene homolog 1		decreases response to substance	EXP	14	105,235,686	105,262,080	RGD:6480464	CTD
G	AKT1	v-akt murine thymoma viral oncogene homolog 1		multiple interactions	EXP	14	105,235,686	105,262,080	RGD:6480464	CTD
G	AKT1	v-akt murine thymoma viral oncogene homolog 1		decreases expression	EXP	14	105,235,686	105,262,080	RGD:6480464	CTD
G	AKT1	v-akt murine thymoma viral oncogene homolog 1		increases phosphorylation	EXP	14	105,235,686	105,262,080	RGD:6480464	CTD
G	AKT1	v-akt murine thymoma viral oncogene homolog 1		decreases phosphorylation	EXP	14	105,235,686	105,262,080	RGD:6480464	CTD
G	AKT1	v-akt murine thymoma viral oncogene homolog 1		decreases phosphorylation	ISO	14	105,235,686	105,262,080	RGD:6480464	CTD
G	AKT1	v-akt murine thymoma viral oncogene homolog 1		decreases expression	ISO	14	105,235,686	105,262,080	RGD:6480464	CTD
G	AKT1	v-akt murine thymoma viral oncogene homolog 1		decreases phosphorylation	EXP	14	105,235,686	105,262,080	RGD:6480464	CTD
G	AKT1	v-akt murine thymoma viral oncogene homolog 1		multiple interactions	ISO	14	105,235,686	105,262,080	RGD:6480464	CTD
G	ALDH18A1	aldehyde dehydrogenase 18 family, member A1		decreases expression	EXP	10	97,365,686	97,416,567	RGD:6480464	CTD
G	ALDH1A1	aldehyde dehydrogenase 1 family, member A1		multiple interactions	ISO	9	75,515,578	75,568,233	RGD:6480464	CTD
G	ALDH9A1	aldehyde dehydrogenase 9 family, member A1		increases expression	ISO	1	165,631,449	165,667,900	RGD:6480464	CTD
G	ANG	angiogenin, ribonuclease, RNase A family, 5		decreases expression	EXP	14	21,152,336	21,162,345	RGD:6480464	CTD
G	ANKRD37	ankyrin repeat domain 37		decreases expression	ISO	4	186,317,840	186,321,390	RGD:6480464	CTD
G	APEX1	APEX nuclease (multifunctional DNA repair enzyme) 1		multiple interactions	ISO	14	20,923,290	20,925,931	RGD:6480464	CTD
G	APOA1	apolipoprotein A-I		multiple interactions	EXP	11	116,706,469	116,708,338	RGD:6480464	CTD
G	APOA2	apolipoprotein A-II		multiple interactions	EXP	1	161,192,083	161,193,418	RGD:6480464	CTD
G	APOB	apolipoprotein B (including Ag(x) antigen)		multiple interactions	EXP	2	21,224,301	21,266,945	RGD:6480464	CTD
G	APOC1	apolipoprotein C-I		multiple interactions	EXP	19	45,417,921	45,422,606	RGD:6480464	CTD
G	APOC2	apolipoprotein C-II		multiple interactions	EXP	19	45,449,239	45,452,822	RGD:6480464	CTD
G	APOC3	apolipoprotein C-III		multiple interactions	EXP	11	116,700,624	116,703,787	RGD:6480464	CTD
G	ARF1	ADP-ribosylation factor 1		multiple interactions	ISO	1	228,270,361	228,286,913	RGD:6480464	CTD
G	ARL6IP1	ADP-ribosylation factor-like 6 interacting protein 1		increases expression	EXP	16	18,802,991	18,812,857	RGD:6480464	CTD
G	ARRB2	arrestin, beta 2		increases expression	ISO	17	4,613,789	4,624,795	RGD:6480464	CTD
G	ASNS	asparagine synthetase (glutamine-hydrolyzing)		decreases expression	EXP	7	97,481,429	97,501,854	RGD:6480464	CTD
G	ATG7	autophagy related 7		increases response to substance	ISO	3	11,314,010	11,599,139	RGD:6480464	CTD
G	ATM	ataxia telangiectasia mutated		multiple interactions	EXP	11	108,093,559	108,239,826	RGD:6480464	CTD
G	ATM	ataxia telangiectasia mutated		decreases activity	EXP	11	108,093,559	108,239,826	RGD:6480464	CTD
G	ATM	ataxia telangiectasia mutated		multiple interactions	EXP	11	108,093,559	108,239,826	RGD:6480464	CTD
G	ATM	ataxia telangiectasia mutated		decreases activity	EXP	11	108,093,559	108,239,826	RGD:6480464	CTD
G	ATM	ataxia telangiectasia mutated		multiple interactions	EXP	11	108,093,559	108,239,826	RGD:6480464	CTD
G	ATM	ataxia telangiectasia mutated		multiple interactions	ISO	11	108,093,559	108,239,826	RGD:6480464	CTD
G	ATM	ataxia telangiectasia mutated		multiple interactions	EXP	11	108,093,559	108,239,826	RGD:6480464	CTD
G	ATM	ataxia telangiectasia mutated		multiple interactions	EXP	11	108,093,559	108,239,826	RGD:6480464	CTD
G	ATP2A2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2		affects response to substance	ISO	12	110,719,032	110,788,898	RGD:6480464	CTD
G	ATP5J2	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2		decreases expression	EXP	7	99,055,784	99,063,824	RGD:6480464	CTD
G	ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c		multiple interactions	ISO	16	2,563,727	2,570,224	RGD:6480464	CTD
G	ATP6V1B2	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2		multiple interactions	ISO	8	20,054,704	20,079,207	RGD:6480464	CTD
G	ATPAF1	ATP synthase mitochondrial F1 complex assembly factor 1		decreases expression	ISO	1	47,100,711	47,134,099	RGD:6480464	CTD
G	ATR	ataxia telangiectasia and Rad3 related		affects activity	EXP	3	142,168,077	142,297,668	RGD:6480464	CTD
G	ATR	ataxia telangiectasia and Rad3 related		multiple interactions	EXP	3	142,168,077	142,297,668	RGD:6480464	CTD
G	ATR	ataxia telangiectasia and Rad3 related		multiple interactions	EXP	3	142,168,077	142,297,668	RGD:6480464	CTD
G	ATR	ataxia telangiectasia and Rad3 related		multiple interactions	EXP	3	142,168,077	142,297,668	RGD:6480464	CTD
G	ATRN	attractin		multiple interactions	ISO	20	3,451,665	3,631,769	RGD:6480464	CTD
G	BAX	BCL2-associated X protein		increases expression	EXP	19	49,458,117	49,465,055	RGD:6480464	CTD
G	BAX	BCL2-associated X protein		increases expression	ISO	19	49,458,117	49,465,055	RGD:6480464	CTD
G	BBC3	BCL2 binding component 3		multiple interactions	EXP	19	47,724,079	47,736,023	RGD:6480464	CTD
G	BID	BH3 interacting domain death agonist		multiple interactions	EXP	22	18,216,906	18,257,431	RGD:6480464	CTD
G	BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3		multiple interactions	ISO	10	133,781,204	133,795,435	RGD:6480464	CTD
G	C1R	complement component 1, r subcomponent		multiple interactions	ISO	12 12	7,241,205 7,187,513	7,245,043 7,189,412	RGD:6480464	CTD
G	C1S	complement component 1, s subcomponent		multiple interactions	ISO	12	7,167,980	7,178,336	RGD:6480464	CTD
G	C2CD5	C2 calcium-dependent domain containing 5		increases expression	ISO	12	22,601,517	22,697,452	RGD:6480464	CTD
G	CALM1	calmodulin 1 (phosphorylase kinase, delta)		multiple interactions	ISO	14	90,863,327	90,874,619	RGD:6480464	CTD
G	CALU	calumenin		decreases expression	EXP	7	128,379,346	128,413,477	RGD:6480464	CTD
G	CAPN1	calpain 1, (mu/I) large subunit		multiple interactions	EXP	11	64,948,686	64,979,477	RGD:6480464	CTD
G	CASP2	caspase 2, apoptosis-related cysteine peptidase		multiple interactions	EXP	7	142,985,308	143,004,789	RGD:6480464	CTD
G	CASP3	caspase 3, apoptosis-related cysteine peptidase		increases activity	EXP	4	185,548,850	185,570,629	RGD:6480464	CTD
G	CASP3	caspase 3, apoptosis-related cysteine peptidase		multiple interactions	EXP	4	185,548,850	185,570,629	RGD:6480464	CTD
G	CASP3	caspase 3, apoptosis-related cysteine peptidase		affects cleavage	EXP	4	185,548,850	185,570,629	RGD:6480464	CTD
G	CASP3	caspase 3, apoptosis-related cysteine peptidase		multiple interactions	EXP	4	185,548,850	185,570,629	RGD:6480464	CTD
G	CASP3	caspase 3, apoptosis-related cysteine peptidase		multiple interactions	EXP	4	185,548,850	185,570,629	RGD:6480464	CTD
G	CASP3	caspase 3, apoptosis-related cysteine peptidase		multiple interactions	EXP	4	185,548,850	185,570,629	RGD:6480464	CTD
G	CASP3	caspase 3, apoptosis-related cysteine peptidase		increases cleavage	ISO	4	185,548,850	185,570,629	RGD:6480464	CTD
G	CASP3	caspase 3, apoptosis-related cysteine peptidase		increases activity	EXP	4	185,548,850	185,570,629	RGD:6480464	CTD
G	CASP3	caspase 3, apoptosis-related cysteine peptidase		multiple interactions	ISO	4	185,548,850	185,570,629	RGD:6480464	CTD
G	CASP3	caspase 3, apoptosis-related cysteine peptidase		increases activity	ISO	4	185,548,850	185,570,629	RGD:6480464	CTD
G	CASP3	caspase 3, apoptosis-related cysteine peptidase		increases cleavage	ISO	4	185,548,850	185,570,629	RGD:6480464	CTD
G	CASP3	caspase 3, apoptosis-related cysteine peptidase		increases expression	ISO	4	185,548,850	185,570,629	RGD:6480464	CTD
G	CASP3	caspase 3, apoptosis-related cysteine peptidase		decreases expression	ISO	4	185,548,850	185,570,629	RGD:6480464	CTD
G	CASP9	caspase 9, apoptosis-related cysteine peptidase		multiple interactions	EXP	1	15,818,769	15,851,285	RGD:6480464	CTD
G	CASP9	caspase 9, apoptosis-related cysteine peptidase		multiple interactions	EXP	1	15,818,769	15,851,285	RGD:6480464	CTD
G	CASP9	caspase 9, apoptosis-related cysteine peptidase		multiple interactions	ISO	1	15,818,769	15,851,285	RGD:6480464	CTD
G	CAT	catalase		multiple interactions	ISO	11	34,460,472	34,493,607	RGD:6480464	CTD
G	CBX5	chromobox homolog 5		multiple interactions	ISO	12	54,624,730	54,673,915	RGD:6480464	CTD
G	CCDC174	coiled-coil domain containing 174		decreases expression	ISO	3	14,693,253	14,714,166	RGD:6480464	CTD
G	CCNB1	cyclin B1		multiple interactions	ISO	5	68,462,837	68,474,072	RGD:6480464	CTD
G	CCNB1	cyclin B1		increases expression	ISO	5	68,462,837	68,474,072	RGD:6480464	CTD
G	CCNB1	cyclin B1		multiple interactions	EXP	5	68,462,837	68,474,072	RGD:6480464	CTD
G	CCND1	cyclin D1		multiple interactions	ISO	11	69,455,873	69,469,242	RGD:6480464	CTD
G	CCNF	cyclin F		multiple interactions	ISO	16	2,479,395	2,508,859	RGD:6480464	CTD
G	CCNL2	cyclin L2		multiple interactions	ISO	1	1,321,091	1,334,718	RGD:6480464	CTD
G	CCZ1	CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)		decreases expression	ISO	7	5,938,341	5,965,605	RGD:6480464	CTD
G	CCZ1	CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)		decreases expression	ISO	7	5,938,341	5,965,605	RGD:6480464	CTD
G	CDC25B	cell division cycle 25B		increases expression	ISO	20	3,776,401	3,786,762	RGD:6480464	CTD
G	CDC25C	cell division cycle 25C		decreases expression	EXP	5	137,620,959	137,667,516	RGD:6480464	CTD
G	CDC25C	cell division cycle 25C		multiple interactions	EXP	5	137,620,959	137,667,516	RGD:6480464	CTD
G	CDC25C	cell division cycle 25C		multiple interactions	EXP	5	137,620,959	137,667,516	RGD:6480464	CTD
G	CDH1	cadherin 1, type 1, E-cadherin (epithelial)		increases expression	ISO	16	68,771,195	68,869,444	RGD:6480464	CTD
G	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)		multiple interactions	ISO	16	64,980,683	65,155,919	RGD:6480464	CTD
G	CDK1	cyclin-dependent kinase 1		multiple interactions	EXP	10	62,538,089	62,554,610	RGD:6480464	CTD
G	CDK1	cyclin-dependent kinase 1		multiple interactions	ISO	10	62,538,089	62,554,610	RGD:6480464	CTD
G	CDK1	cyclin-dependent kinase 1		multiple interactions	EXP	10	62,538,089	62,554,610	RGD:6480464	CTD
G	CDK1	cyclin-dependent kinase 1		multiple interactions	EXP	10	62,538,089	62,554,610	RGD:6480464	CTD
G	CDK2	cyclin-dependent kinase 2		decreases activity	EXP	12	56,360,556	56,366,568	RGD:6480464	CTD
G	CDK4	cyclin-dependent kinase 4		multiple interactions	ISO	12	58,141,510	58,146,230	RGD:6480464	CTD
G	CDK4	cyclin-dependent kinase 4		decreases expression	EXP	12	58,141,510	58,146,230	RGD:6480464	CTD
G	CDK4	cyclin-dependent kinase 4		multiple interactions	ISO	12	58,141,510	58,146,230	RGD:6480464	CTD
G	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)		multiple interactions	EXP	6	36,644,237	36,655,116	RGD:6480464	CTD
G	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)		multiple interactions	EXP	6	36,644,237	36,655,116	RGD:6480464	CTD
G	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)		multiple interactions	EXP	6	36,644,237	36,655,116	RGD:6480464	CTD
G	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)		multiple interactions	EXP	6	36,644,237	36,655,116	RGD:6480464	CTD
G	CETN3	centrin, EF-hand protein, 3		multiple interactions	ISO	5	89,689,528	89,705,603	RGD:6480464	CTD
G	CHEK1	checkpoint kinase 1		multiple interactions	EXP	11	125,495,031	125,546,150	RGD:6480464	CTD
G	CHEK1	checkpoint kinase 1		multiple interactions	EXP	11	125,495,031	125,546,150	RGD:6480464	CTD
G	CHEK1	checkpoint kinase 1		decreases phosphorylation	EXP	11	125,495,031	125,546,150	RGD:6480464	CTD
G	CHEK1	checkpoint kinase 1		decreases expression	ISO	11	125,495,031	125,546,150	RGD:6480464	CTD
G	CHEK1	checkpoint kinase 1		multiple interactions	EXP	11	125,495,031	125,546,150	RGD:6480464	CTD
G	CHEK2	checkpoint kinase 2		multiple interactions	EXP	22	29,083,731	29,137,822	RGD:6480464	CTD
G	CHEK2	checkpoint kinase 2		decreases activity	EXP	22	29,083,731	29,137,822	RGD:6480464	CTD
G	CHEK2	checkpoint kinase 2		multiple interactions	EXP	22	29,083,731	29,137,822	RGD:6480464	CTD
G	CHEK2	checkpoint kinase 2		multiple interactions	EXP	22	29,083,731	29,137,822	RGD:6480464	CTD
G	CHEK2	checkpoint kinase 2		multiple interactions	EXP	22	29,083,731	29,137,822	RGD:6480464	CTD
G	CKMT1B	creatine kinase, mitochondrial 1B		multiple interactions	ISO	15	43,885,252	43,891,604	RGD:6480464	CTD
G	CLSTN1	calsyntenin 1		multiple interactions	ISO	1	9,789,079	9,884,550	RGD:6480464	CTD
G	CNN2	calponin 2		multiple interactions	ISO	19	1,026,298	1,039,064	RGD:6480464	CTD
G	COBL	cordon-bleu WH2 repeat protein		affects expression	ISO	7	51,083,909	51,384,515	RGD:6480464	CTD
G	COCH	coagulation factor C homolog, cochlin (Limulus polyphemus)		decreases expression	ISO	14	31,343,741	31,359,822	RGD:6480464	CTD
G	COCH	coagulation factor C homolog, cochlin (Limulus polyphemus)		decreases expression	ISO	14	31,343,741	31,359,822	RGD:6480464	CTD
G	COL1A1	collagen, type I, alpha 1		multiple interactions	ISO	17	48,261,457	48,279,000	RGD:6480464	CTD
G	COX7A2L	cytochrome c oxidase subunit VIIa polypeptide 2 like		multiple interactions	ISO	2	42,577,642	42,588,356	RGD:6480464	CTD
G	COX7C	cytochrome c oxidase subunit VIIc		multiple interactions	ISO	5	85,913,784	85,916,583	RGD:6480464	CTD
G	CSNK2A2	casein kinase 2, alpha prime polypeptide		decreases expression	ISO	16	58,191,811	58,231,782	RGD:6480464	CTD
G	CST3	cystatin C		multiple interactions	ISO	20	23,614,294	23,618,574	RGD:6480464	CTD
G	CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa		increases mutagenesis	ISO	3	41,240,942	41,281,939	RGD:6480464	CTD
G	CTSB	cathepsin B		multiple interactions	EXP	8	11,700,033	11,725,646	RGD:6480464	CTD
G	CTSB	cathepsin B		multiple interactions	ISO	8	11,700,033	11,725,646	RGD:6480464	CTD
G	CTSL1	cathepsin L1		multiple interactions	ISO	9	90,340,974	90,346,384	RGD:6480464	CTD
G	CYC1	cytochrome c-1		decreases expression	EXP	8	145,149,960	145,152,428	RGD:6480464	CTD
G	CYCS	cytochrome c, somatic		multiple interactions	EXP	7	25,158,270	25,164,980	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		affects metabolic processing	EXP	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		multiple interactions	EXP	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		affects metabolic processing	EXP	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		affects metabolic processing	EXP	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		decreases activity	EXP	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		multiple interactions	EXP	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		affects metabolic processing	EXP	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		multiple interactions	EXP	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		affects binding	EXP	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		decreases methylation	EXP	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		increases metabolic processing	EXP	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		multiple interactions	EXP	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		decreases methylation	ISO	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		increases activity	ISO	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		affects metabolic processing	ISO	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		multiple interactions	ISO	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		multiple interactions	EXP	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		affects metabolic processing	EXP	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		affects metabolic processing	EXP	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		decreases methylation	EXP	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		affects metabolic processing	EXP	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		affects metabolic processing	EXP	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		increases metabolic processing	EXP	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		multiple interactions	EXP	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2		multiple interactions	ISO	15	75,041,184	75,048,941	RGD:6480464	CTD
G	CYP2A6	cytochrome P450, family 2, subfamily A, polypeptide 6		multiple interactions	EXP	19	41,349,443	41,356,352	RGD:6480464	CTD
G	CYP2A6	cytochrome P450, family 2, subfamily A, polypeptide 6		increases metabolic processing	EXP	19	41,349,443	41,356,352	RGD:6480464	CTD
G	CYP2D6	cytochrome P450, family 2, subfamily D, polypeptide 6		affects metabolic processing	EXP	22	42,522,501	42,526,883	RGD:6480464	CTD
G	CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1		affects metabolic processing	EXP	10	135,340,867	135,352,620	RGD:6480464	CTD
G	CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1		affects metabolic processing	EXP	10	135,340,867	135,352,620	RGD:6480464	CTD
G	CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1		affects metabolic processing	EXP	10	135,340,867	135,352,620	RGD:6480464	CTD
G	CYP4B1	cytochrome P450, family 4, subfamily B, polypeptide 1		increases expression	EXP	1	47,264,670	47,285,021	RGD:6480464	CTD
G	CYP7B1	cytochrome P450, family 7, subfamily B, polypeptide 1		decreases expression	ISO	8	65,508,529	65,711,348	RGD:6480464	CTD
G	DAD1	defender against cell death 1		decreases expression	EXP	14	23,033,807	23,058,143	RGD:6480464	CTD
G	DCAF11	DDB1 and CUL4 associated factor 11		decreases expression	ISO	14	24,583,906	24,594,451	RGD:6480464	CTD
G	DCT	dopachrome tautomerase		increases expression	EXP	13	95,091,835	95,131,936	RGD:6480464	CTD
G	DCXR	dicarbonyl/L-xylulose reductase		multiple interactions	ISO	17	79,993,757	79,995,573	RGD:6480464	CTD
G	DDHD1	DDHD domain containing 1		increases expression	ISO	14	53,503,458	53,620,046	RGD:6480464	CTD
G	DDX31	DEAD (Asp-Glu-Ala-Asp) box polypeptide 31		decreases expression	ISO	9	135,469,676	135,545,788	RGD:6480464	CTD
G	DHCR24	24-dehydrocholesterol reductase		decreases expression	ISO	1	55,315,300	55,352,921	RGD:6480464	CTD
G	DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1		multiple interactions	ISO	9	33,025,209	33,039,062	RGD:6480464	CTD
G	DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9		multiple interactions	ISO	7	108,210,189	108,215,294	RGD:6480464	CTD
G	DPP4	dipeptidyl-peptidase 4		multiple interactions	ISO	2	162,848,755	162,931,052	RGD:6480464	CTD
G	DRD2	dopamine receptor D2		affects response to substance	EXP	11	113,280,317	113,346,001	RGD:6480464	CTD
G	DRD2	dopamine receptor D2		multiple interactions	ISO	11	113,280,317	113,346,001	RGD:6480464	CTD
G	DRD2	dopamine receptor D2		increases response to substance	ISO	11	113,280,317	113,346,001	RGD:6480464	CTD
G	DTX4	deltex homolog 4 (Drosophila)		decreases expression	ISO	11	58,939,812	58,976,060	RGD:6480464	CTD
G	DUSP8	dual specificity phosphatase 8		increases expression	ISO	11	1,575,281	1,593,150	RGD:6480464	CTD
G	EBPL	emopamil binding protein-like		decreases expression	ISO	13	50,234,810	50,265,623	RGD:6480464	CTD
G	ECI1	enoyl-CoA delta isomerase 1		decreases expression	ISO	16	2,289,873	2,301,602	RGD:6480464	CTD
G	ECM1	extracellular matrix protein 1		multiple interactions	ISO	1	150,480,487	150,486,265	RGD:6480464	CTD
G	EDN1	endothelin 1		increases activity	ISO	6	12,290,529	12,297,427	RGD:6480464	CTD
G	EEF1A1	eukaryotic translation elongation factor 1 alpha 1		multiple interactions	ISO	6	74,225,473	74,230,755	RGD:6480464	CTD
G	EEF2	eukaryotic translation elongation factor 2		multiple interactions	ISO	19	3,976,054	3,985,461	RGD:6480464	CTD
G	EFNA1	ephrin-A1		multiple interactions	ISO	1	155,100,349	155,107,386	RGD:6480464	CTD
G	EFNB3	ephrin-B3		multiple interactions	ISO	17	7,608,520	7,614,693	RGD:6480464	CTD
G	EGR1	early growth response 1		increases expression	ISO	5	137,801,181	137,805,004	RGD:6480464	CTD
G	EGR1	early growth response 1		multiple interactions	ISO	5	137,801,181	137,805,004	RGD:6480464	CTD
G	EGR1	early growth response 1		multiple interactions	ISO	5	137,801,181	137,805,004	RGD:6480464	CTD
G	EGR1	early growth response 1		decreases expression	ISO	5	137,801,181	137,805,004	RGD:6480464	CTD
G	EIF1	eukaryotic translation initiation factor 1		increases expression	EXP	17	39,845,127	39,847,898	RGD:6480464	CTD
G	EIF4E	eukaryotic translation initiation factor 4E		multiple interactions	ISO	4	99,799,607	99,851,786	RGD:6480464	CTD
G	EIF4EBP1	eukaryotic translation initiation factor 4E binding protein 1		decreases expression	EXP	8	37,888,020	37,917,883	RGD:6480464	CTD
G	EIF4EBP1	eukaryotic translation initiation factor 4E binding protein 1		increases expression	EXP	8	37,888,020	37,917,883	RGD:6480464	CTD
G	EIF4EBP1	eukaryotic translation initiation factor 4E binding protein 1		increases expression	ISO	8	37,888,020	37,917,883	RGD:6480464	CTD
G	EIF4EBP1	eukaryotic translation initiation factor 4E binding protein 1		decreases expression	ISO	8	37,888,020	37,917,883	RGD:6480464	CTD
G	EIF5	eukaryotic translation initiation factor 5		multiple interactions	ISO	14	103,800,339	103,811,362	RGD:6480464	CTD
G	ELL	elongation factor RNA polymerase II		decreases expression	ISO	19	18,553,473	18,632,937	RGD:6480464	CTD
G	EMC6	ER membrane protein complex subunit 6		decreases expression	ISO	17	3,572,090	3,572,962	RGD:6480464	CTD
G	ENDOD1	endonuclease domain containing 1		decreases expression	ISO	11	94,822,974	94,865,815	RGD:6480464	CTD
G	ENO1	enolase 1, (alpha)		multiple interactions	ISO	1	8,921,059	8,939,151	RGD:6480464	CTD
G	ENO1	enolase 1, (alpha)		multiple interactions	ISO	1	8,921,059	8,939,151	RGD:6480464	CTD
G	ERN1	endoplasmic reticulum to nucleus signaling 1		multiple interactions	ISO	17	62,120,390	62,207,502	RGD:6480464	CTD
G	ERP44	endoplasmic reticulum protein 44		multiple interactions	ISO	9	102,741,461	102,861,330	RGD:6480464	CTD
G	ESYT2	extended synaptotagmin-like protein 2		decreases expression	ISO	7	158,523,689	158,622,319	RGD:6480464	CTD
G	EZR	ezrin		multiple interactions	ISO	6	159,186,773	159,240,456	RGD:6480464	CTD
G	FASTKD3	FAST kinase domains 3		decreases expression	ISO	5	7,859,272	7,869,150	RGD:6480464	CTD
G	FBLN2	fibulin 2		increases expression	ISO	3	13,590,625	13,679,922	RGD:6480464	CTD
G	FBRS	fibrosin		increases expression	ISO	16	30,675,778	30,682,131	RGD:6480464	CTD
G	FBXL12	F-box and leucine-rich repeat protein 12		multiple interactions	ISO	19	9,920,943	9,929,731	RGD:6480464	CTD
G	FDFT1	farnesyl-diphosphate farnesyltransferase 1		decreases expression	ISO	8	11,660,190	11,696,818	RGD:6480464	CTD
G	FDX1	ferredoxin 1		decreases expression	ISO	11	110,300,661	110,335,608	RGD:6480464	CTD
G	FHL1	four and a half LIM domains 1		increases expression	ISO	X	135,228,861	135,293,518	RGD:6480464	CTD
G	FILIP1L	filamin A interacting protein 1-like		increases expression	ISO	3	99,551,988	99,833,349	RGD:6480464	CTD
G	FOS	FBJ murine osteosarcoma viral oncogene homolog		increases expression	ISO	14	75,745,481	75,748,937	RGD:6480464	CTD
G	FOS	FBJ murine osteosarcoma viral oncogene homolog		multiple interactions	ISO	14	75,745,481	75,748,937	RGD:6480464	CTD
G	FUK	fucokinase		increases expression	ISO	16	70,488,498	70,514,177	RGD:6480464	CTD
G	FYN	FYN oncogene related to SRC, FGR, YES		multiple interactions	ISO	6	111,981,535	112,194,655	RGD:6480464	CTD
G	GALE	UDP-galactose-4-epimerase		multiple interactions	ISO	1	24,122,089	24,127,294	RGD:6480464	CTD
G	GAPDH	glyceraldehyde-3-phosphate dehydrogenase		multiple interactions	ISO	12	6,643,585	6,647,537	RGD:6480464	CTD
G	GAST	gastrin		increases secretion	ISO	17	39,868,578	39,872,221	RGD:6480464	CTD
G	GDF10	growth differentiation factor 10		decreases expression	ISO	10	48,425,785	48,439,138	RGD:6480464	CTD
G	GFAP	glial fibrillary acidic protein		multiple interactions	ISO	17	42,982,994	42,992,920	RGD:6480464	CTD
G	GH1	growth hormone 1		multiple interactions	EXP	17	61,994,563	61,996,198	RGD:6480464	CTD
G	GHITM	growth hormone inducible transmembrane protein		multiple interactions	ISO	10	85,899,185	85,913,311	RGD:6480464	CTD
G	GLRX	glutaredoxin (thioltransferase)		decreases expression	EXP	5	95,149,553	95,158,577	RGD:6480464	CTD
G	GLT8D1	glycosyltransferase 8 domain containing 1		decreases expression	EXP	3	52,728,504	52,740,048	RGD:6480464	CTD
G	GLUD1	glutamate dehydrogenase 1		decreases expression	EXP	10	88,809,959	88,854,776	RGD:6480464	CTD
G	GMFB	glia maturation factor, beta		multiple interactions	ISO	14	54,941,209	54,955,744	RGD:6480464	CTD
G	GNAI1	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1		decreases expression	ISO	7	79,764,140	79,848,725	RGD:6480464	CTD
G	GNAI1	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1		increases expression	ISO	7	79,764,140	79,848,725	RGD:6480464	CTD
G	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2		decreases expression	ISO	3	50,273,647	50,296,786	RGD:6480464	CTD
G	GNAL	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type		increases response to substance	ISO	18	11,689,014	11,885,684	RGD:6480464	CTD
G	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide		decreases expression	ISO	9	80,335,189	80,646,219	RGD:6480464	CTD
G	GNAS	GNAS complex locus		decreases expression	ISO	20	57,414,795	57,486,250	RGD:6480464	CTD
G	GOLT1B	golgi transport 1B		multiple interactions	ISO	12	21,654,699	21,671,337	RGD:6480464	CTD
G	GOSR1	golgi SNAP receptor complex member 1		decreases expression	ISO	17	28,804,426	28,853,832	RGD:6480464	CTD
G	GPC3	glypican 3		affects expression	ISO	X	132,669,773	133,119,673	RGD:6480464	CTD
G	GPT	glutamic-pyruvate transaminase (alanine aminotransferase)		multiple interactions	ISO	8	145,729,465	145,732,555	RGD:6480464	CTD
G	GPX3	glutathione peroxidase 3 (plasma)		multiple interactions	ISO	5	150,399,999	150,408,554	RGD:6480464	CTD
G	GRID2	glutamate receptor, ionotropic, delta 2		multiple interactions	ISO	4	93,225,550	94,693,649	RGD:6480464	CTD
G	GRM1	glutamate receptor, metabotropic 1		decreases expression	ISO	6	146,348,782	146,758,731	RGD:6480464	CTD
G	GRPR	gastrin-releasing peptide receptor		decreases expression	ISO	X	16,141,424	16,171,641	RGD:6480464	CTD
G	GRWD1	glutamate-rich WD repeat containing 1		decreases expression	ISO	19	48,949,030	48,957,164	RGD:6480464	CTD
G	GSK3B	glycogen synthase kinase 3 beta		increases phosphorylation	EXP	3	119,540,800	119,813,264	RGD:6480464	CTD
G	GSK3B	glycogen synthase kinase 3 beta		multiple interactions	EXP	3	119,540,800	119,813,264	RGD:6480464	CTD
G	GSK3B	glycogen synthase kinase 3 beta		decreases phosphorylation	ISO	3	119,540,800	119,813,264	RGD:6480464	CTD
G	GSTO1	glutathione S-transferase omega 1		decreases expression	EXP	10	106,013,952	106,027,222	RGD:6480464	CTD
G	H2AFX	H2A histone family, member X		multiple interactions	EXP	11	118,964,584	118,966,177	RGD:6480464	CTD
G	H2AFX	H2A histone family, member X		multiple interactions	ISO	11	118,964,584	118,966,177	RGD:6480464	CTD
G	H2AFX	H2A histone family, member X		multiple interactions	EXP	11	118,964,584	118,966,177	RGD:6480464	CTD
G	H2AFX	H2A histone family, member X		multiple interactions	EXP	11	118,964,584	118,966,177	RGD:6480464	CTD
G	HBA2	hemoglobin, alpha 2		multiple interactions	ISO	16	222,846	223,709	RGD:6480464	CTD
G	HECA	headcase homolog (Drosophila)		increases expression	ISO	6	139,456,249	139,501,946	RGD:6480464	CTD
G	HELLS	helicase, lymphoid-specific		multiple interactions	ISO	10	96,305,574	96,361,856	RGD:6480464	CTD
G	HELLS	helicase, lymphoid-specific		increases expression	ISO	10	96,305,574	96,361,856	RGD:6480464	CTD
G	HINT1	histidine triad nucleotide binding protein 1		multiple interactions	ISO	5	130,494,875	130,501,034	RGD:6480464	CTD
G	HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)		decreases expression	ISO	5	43,287,572	43,313,614	RGD:6480464	CTD
G	HOMER1	homer homolog 1 (Drosophila)		multiple interactions	ISO	5	78,669,786	78,809,700	RGD:6480464	CTD
G	HRAS	v-Ha-ras Harvey rat sarcoma viral oncogene homolog		multiple interactions	ISO	11	532,242	535,550	RGD:6480464	CTD
G	HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1		increases expression	ISO	1	209,859,525	209,908,295	RGD:6480464	CTD
G	HSD11B2	hydroxysteroid (11-beta) dehydrogenase 2		decreases expression	ISO	16	67,465,036	67,471,456	RGD:6480464	CTD
G	HSD11B2	hydroxysteroid (11-beta) dehydrogenase 2		decreases expression	EXP	16	67,465,036	67,471,456	RGD:6480464	CTD
G	HSD11B2	hydroxysteroid (11-beta) dehydrogenase 2		multiple interactions	EXP	16	67,465,036	67,471,456	RGD:6480464	CTD
G	HSD17B7	hydroxysteroid (17-beta) dehydrogenase 7		decreases expression	ISO	1	162,760,496	162,782,608	RGD:6480464	CTD
G	HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1		multiple interactions	ISO	14	102,547,075	102,606,086	RGD:6480464	CTD
G	HSPB1	heat shock 27kDa protein 1		increases expression	ISO	7	75,931,875	75,933,614	RGD:6480464	CTD
G	HSPB6	heat shock protein, alpha-crystallin-related, B6		increases expression	ISO	19	36,245,467	36,247,930	RGD:6480464	CTD
G	HSPE1	heat shock 10kDa protein 1 (chaperonin 10)		multiple interactions	ISO	2	198,364,721	198,368,187	RGD:6480464	CTD
G	HSPE1	heat shock 10kDa protein 1 (chaperonin 10)		multiple interactions	ISO	2	198,364,721	198,368,187	RGD:6480464	CTD
G	ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein		increases expression	ISO	1	23,884,421	23,886,285	RGD:6480464	CTD
G	IDI1	isopentenyl-diphosphate delta isomerase 1		decreases expression	ISO	10	1,085,963	1,095,061	RGD:6480464	CTD
G	IGF1	insulin-like growth factor 1 (somatomedin C)		decreases secretion	ISO	12	102,789,645	102,874,378	RGD:6480464	CTD
G	IGF1	insulin-like growth factor 1 (somatomedin C)		decreases expression	ISO	12	102,789,645	102,874,378	RGD:6480464	CTD
G	IGF1R	insulin-like growth factor 1 receptor		decreases expression	ISO	15	99,192,761	99,507,759	RGD:6480464	CTD
G	IGFBP1	insulin-like growth factor binding protein 1		increases expression	EXP	7	45,927,959	45,933,267	RGD:6480464	CTD
G	IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta		increases expression	ISO	8	42,128,820	42,190,171	RGD:6480464	CTD
G	IL10RB	interleukin 10 receptor, beta		increases expression	ISO	21	34,638,665	34,669,539	RGD:6480464	CTD
G	IL1RL1	interleukin 1 receptor-like 1		increases expression	ISO	2	102,927,962	102,968,497	RGD:6480464	CTD
G	IL4R	interleukin 4 receptor		increases expression	ISO	16	27,325,230	27,376,099	RGD:6480464	CTD
G	IL4R	interleukin 4 receptor		multiple interactions	ISO	16	27,325,230	27,376,099	RGD:6480464	CTD
G	INO80C	INO80 complex subunit C		decreases expression	ISO	18	33,048,291	33,077,955	RGD:6480464	CTD
G	INS	insulin		multiple interactions	EXP	11	2,181,009	2,182,439	RGD:6480464	CTD
G	INSIG1	insulin induced gene 1		decreases expression	ISO	7	155,089,486	155,101,945	RGD:6480464	CTD
G	INSR	insulin receptor		decreases expression	ISO	19	7,112,266	7,294,011	RGD:6480464	CTD
G	IRAK1	interleukin-1 receptor-associated kinase 1		multiple interactions	ISO	X	153,275,957	153,285,342	RGD:6480464	CTD
G	IRX3	iroquois homeobox 3		multiple interactions	ISO	16	54,317,212	54,320,378	RGD:6480464	CTD
G	ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)		multiple interactions	ISO	16	31,271,288	31,344,213	RGD:6480464	CTD
G	ITM2B	integral membrane protein 2B		multiple interactions	ISO	13	48,807,274	48,836,232	RGD:6480464	CTD
G	ITPR1	inositol 1,4,5-trisphosphate receptor, type 1		decreases expression	EXP	3	4,535,032	4,889,524	RGD:6480464	CTD
G	JUN	jun proto-oncogene		decreases phosphorylation	ISO	1	59,246,463	59,249,785	RGD:6480464	CTD
G	JUN	jun proto-oncogene		increases expression	ISO	1	59,246,463	59,249,785	RGD:6480464	CTD
G	KCTD14	potassium channel tetramerisation domain containing 14		decreases expression	ISO	11	77,726,761	77,734,320	RGD:6480464	CTD
G	KIDINS220	kinase D-interacting substrate, 220kDa		increases expression	ISO	2	8,868,987	8,977,755	RGD:6480464	CTD
G	KIF3B	kinesin family member 3B		multiple interactions	ISO	20	30,865,454	30,922,814	RGD:6480464	CTD
G	KLF4	Kruppel-like factor 4 (gut)		multiple interactions	ISO	9	110,247,133	110,252,047	RGD:6480464	CTD
G	LDHA	lactate dehydrogenase A		decreases expression	EXP	11	18,415,936	18,429,765	RGD:6480464	CTD
G	LEPR	leptin receptor		increases expression	ISO	1	65,886,335	66,103,176	RGD:6480464	CTD
G	LEPREL2	leprecan-like 2		multiple interactions	ISO	12	6,937,572	6,949,018	RGD:6480464	CTD
G	LPAR4	lysophosphatidic acid receptor 4		multiple interactions	ISO	X	78,003,206	78,012,588	RGD:6480464	CTD
G	LPHN1	latrophilin 1		multiple interactions	ISO	19	14,258,549	14,316,997	RGD:6480464	CTD
G	LYSMD2	LysM, putative peptidoglycan-binding, domain containing 2		decreases expression	ISO	15	52,015,261	52,043,650	RGD:6480464	CTD
G	MAOA	monoamine oxidase A		multiple interactions	ISO	X	43,514,155	43,606,071	RGD:6480464	CTD
G	MAP2K7	mitogen-activated protein kinase kinase 7		multiple interactions	ISO	19	7,968,765	7,979,363	RGD:6480464	CTD
G	MAP3K12	mitogen-activated protein kinase kinase kinase 12		multiple interactions	ISO	12	53,874,276	53,893,444	RGD:6480464	CTD
G	MAPK1	mitogen-activated protein kinase 1		increases expression	EXP	22	22,113,946	22,221,970	RGD:6480464	CTD
G	MAPK1	mitogen-activated protein kinase 1		decreases phosphorylation	ISO	22	22,113,946	22,221,970	RGD:6480464	CTD
G	MAPK1	mitogen-activated protein kinase 1		multiple interactions	ISO	22	22,113,946	22,221,970	RGD:6480464	CTD
G	MAPK15	mitogen-activated protein kinase 15		increases expression	ISO	8	144,798,507	144,804,633	RGD:6480464	CTD
G	MAPK3	mitogen-activated protein kinase 3		increases expression	EXP	16	30,125,426	30,134,630	RGD:6480464	CTD
G	MAPK3	mitogen-activated protein kinase 3		decreases phosphorylation	ISO	16	30,125,426	30,134,630	RGD:6480464	CTD
G	MAPK3	mitogen-activated protein kinase 3		multiple interactions	ISO	16	30,125,426	30,134,630	RGD:6480464	CTD
G	MARCH11	membrane-associated ring finger (C3HC4) 11		decreases expression	ISO	5	16,067,474	16,179,897	RGD:6480464	CTD
G	MARCH11	membrane-associated ring finger (C3HC4) 11		decreases expression	ISO	5	16,067,474	16,179,897	RGD:6480464	CTD
G	MC2R	melanocortin 2 receptor (adrenocorticotropic hormone)		multiple interactions	ISO	18	13,882,043	13,915,535	RGD:6480464	CTD
G	MCM3	minichromosome maintenance complex component 3		increases expression	ISO	6	52,128,812	52,149,679	RGD:6480464	CTD
G	MGST1	microsomal glutathione S-transferase 1		decreases expression	EXP	12	16,500,076	16,530,123	RGD:6480464	CTD
G	MICB	MHC class I polypeptide-related sequence B		multiple interactions	EXP	6	31,465,855	31,478,901	RGD:6480464	CTD
G	MICB	MHC class I polypeptide-related sequence B		multiple interactions	EXP	6	31,465,855	31,478,901	RGD:6480464	CTD
G	MMP7	matrix metallopeptidase 7 (matrilysin, uterine)		multiple interactions	ISO	11	102,391,239	102,401,478	RGD:6480464	CTD
G	MOGAT1	monoacylglycerol O-acyltransferase 1		decreases expression	ISO	2	223,536,457	223,574,649	RGD:6480464	CTD
G	MOGAT1	monoacylglycerol O-acyltransferase 1		decreases expression	ISO	2	223,536,457	223,574,649	RGD:6480464	CTD
G	MRPL19	mitochondrial ribosomal protein L19		decreases expression	ISO	2	75,873,909	75,889,334	RGD:6480464	CTD
G	MRPL20	mitochondrial ribosomal protein L20		multiple interactions	ISO	1	1,337,276	1,342,693	RGD:6480464	CTD
G	MRPL9	mitochondrial ribosomal protein L9		multiple interactions	ISO	1	151,732,123	151,736,040	RGD:6480464	CTD
G	MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)		decreases expression	ISO	2	47,630,206	47,710,367	RGD:6480464	CTD
G	MSMO1	methylsterol monooxygenase 1		decreases expression	ISO	4	166,248,818	166,264,316	RGD:6480464	CTD
G	MT1G	metallothionein 1G		increases expression	EXP	16	56,700,653	56,701,977	RGD:6480464	CTD
G	MT2A	metallothionein 2A		multiple interactions	ISO	16	56,642,478	56,643,409	RGD:6480464	CTD
G	MTCH1	mitochondrial carrier 1		multiple interactions	ISO	6	36,935,917	36,953,949	RGD:6480464	CTD
G	MTF2	metal response element binding transcription factor 2		multiple interactions	ISO	1	93,544,792	93,604,638	RGD:6480464	CTD
G	MTHFD2L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like		decreases expression	ISO	4	75,023,829	75,168,816	RGD:6480464	CTD
G	MTOR	mechanistic target of rapamycin (serine/threonine kinase)		decreases activity	EXP	1	11,166,588	11,322,608	RGD:6480464	CTD
G	MTRR	5-methyltetrahydrofolate-homocysteine methyltransferase reductase		decreases expression	ISO	5	7,869,217	7,901,237	RGD:6480464	CTD
G	MUTYH	mutY homolog (E. coli)		increases expression	ISO	1	45,794,914	45,806,142	RGD:6480464	CTD
G	MYC	v-myc myelocytomatosis viral oncogene homolog (avian)		multiple interactions	ISO	8	128,748,315	128,753,680	RGD:6480464	CTD
G	NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)		affects metabolic processing	EXP	8	18,248,755	18,258,723	RGD:6480464	CTD
G	NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)		affects metabolic processing	EXP	8	18,248,755	18,258,723	RGD:6480464	CTD
G	NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)		affects metabolic processing	EXP	8	18,248,755	18,258,723	RGD:6480464	CTD
G	NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)		increases acetylation	EXP	8	18,248,755	18,258,723	RGD:6480464	CTD
G	NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)		affects metabolic processing	EXP	8	18,248,755	18,258,723	RGD:6480464	CTD
G	NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)		affects metabolic processing	EXP	8	18,248,755	18,258,723	RGD:6480464	CTD
G	NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)		affects metabolic processing	EXP	8	18,248,755	18,258,723	RGD:6480464	CTD
G	NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)		affects metabolic processing	EXP	8	18,248,755	18,258,723	RGD:6480464	CTD
G	NDUFB5	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa		multiple interactions	ISO	3	179,322,575	179,342,288	RGD:6480464	CTD
G	NDUFS4	NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)		multiple interactions	ISO	5	52,856,465	52,979,171	RGD:6480464	CTD
G	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1		multiple interactions	ISO	4	103,422,486	103,538,459	RGD:6480464	CTD
G	NISCH	nischarin		multiple interactions	ISO	3	52,489,524	52,527,088	RGD:6480464	CTD
G	NOS2	nitric oxide synthase 2, inducible		multiple interactions	ISO	17	26,083,792	26,127,555	RGD:6480464	CTD
G	NPL	N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)		multiple interactions	ISO	1	182,758,584	182,799,519	RGD:6480464	CTD
G	NPPA	natriuretic peptide A		multiple interactions	ISO	1	11,905,766	11,907,840	RGD:6480464	CTD
G	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)		increases expression	ISO	5	142,657,496	142,815,077	RGD:6480464	CTD
G	NR3C2	nuclear receptor subfamily 3, group C, member 2		increases expression	ISO	4	148,999,915	149,363,672	RGD:6480464	CTD
G	NRF1	nuclear respiratory factor 1		decreases expression	ISO	7	129,251,555	129,396,922	RGD:6480464	CTD
G	NSF	N-ethylmaleimide-sensitive factor		multiple interactions	ISO	17	44,668,035	44,834,830	RGD:6480464	CTD
G	NUPR1	nuclear protein, transcriptional regulator, 1		multiple interactions	ISO	16	28,548,662	28,550,495	RGD:6480464	CTD
G	OAT	ornithine aminotransferase		increases expression	EXP	10	126,085,872	126,107,545	RGD:6480464	CTD
G	ORM1	orosomucoid 1		increases expression	ISO	9	117,085,303	117,088,759	RGD:6480464	CTD
G	ORM2	orosomucoid 2		increases expression	ISO	9	117,092,069	117,095,536	RGD:6480464	CTD
G	OXSR1	oxidative-stress responsive 1		increases expression	ISO	3	38,207,026	38,296,979	RGD:6480464	CTD
G	PAK2	p21 protein (Cdc42/Rac)-activated kinase 2		increases activity	EXP	3	196,466,728	196,559,518	RGD:6480464	CTD
G	PAK2	p21 protein (Cdc42/Rac)-activated kinase 2		multiple interactions	ISO	3	196,466,728	196,559,518	RGD:6480464	CTD
G	PARP1	poly (ADP-ribose) polymerase 1		multiple interactions	EXP	1	226,548,392	226,595,801	RGD:6480464	CTD
G	PARP1	poly (ADP-ribose) polymerase 1		multiple interactions	EXP	1	226,548,392	226,595,801	RGD:6480464	CTD
G	PARP1	poly (ADP-ribose) polymerase 1		affects cleavage	EXP	1	226,548,392	226,595,801	RGD:6480464	CTD
G	PARP1	poly (ADP-ribose) polymerase 1		multiple interactions	EXP	1	226,548,392	226,595,801	RGD:6480464	CTD
G	PARP1	poly (ADP-ribose) polymerase 1		increases cleavage	EXP	1	226,548,392	226,595,801	RGD:6480464	CTD
G	PDE11A	phosphodiesterase 11A		decreases expression	ISO	2	178,487,977	178,973,066	RGD:6480464	CTD
G	PDE5A	phosphodiesterase 5A, cGMP-specific		decreases expression	ISO	4	120,415,550	120,549,981	RGD:6480464	CTD
G	PDHX	pyruvate dehydrogenase complex, component X		decreases expression	ISO	11	34,937,677	35,017,675	RGD:6480464	CTD
G	PDHX	pyruvate dehydrogenase complex, component X		decreases expression	ISO	11	34,937,677	35,017,675	RGD:6480464	CTD
G	PDIA6	protein disulfide isomerase family A, member 6		multiple interactions	ISO	2	10,923,517	10,952,960	RGD:6480464	CTD
G	PFDN1	prefoldin subunit 1		multiple interactions	ISO	5	139,624,635	139,682,689	RGD:6480464	CTD
G	PGR	progesterone receptor		increases expression	ISO	11	100,900,355	101,000,544	RGD:6480464	CTD
G	PHB	prohibitin		multiple interactions	ISO	17	47,481,420	47,492,242	RGD:6480464	CTD
G	PHEX	phosphate regulating endopeptidase homolog, X-linked		increases expression	ISO	X	22,050,921	22,266,478	RGD:6480464	CTD
G	PHTF1	putative homeodomain transcription factor 1		multiple interactions	ISO	1	114,239,824	114,301,777	RGD:6480464	CTD
G	PIDD	p53-induced death domain protein		multiple interactions	ISO	11	799,179	805,250	RGD:6480464	CTD
G	PIGC	phosphatidylinositol glycan anchor biosynthesis, class C		multiple interactions	ISO	1	172,410,597	172,413,230	RGD:6480464	CTD
G	PIP5K1C	phosphatidylinositol-4-phosphate 5-kinase, type I, gamma		multiple interactions	ISO	19	3,630,179	3,700,477	RGD:6480464	CTD
G	PITX2	paired-like homeodomain 2		decreases expression	ISO	4	111,538,579	111,563,279	RGD:6480464	CTD
G	PKD1	polycystic kidney disease 1 (autosomal dominant)		multiple interactions	ISO	16	2,138,711	2,185,899	RGD:6480464	CTD
G	PKD1	polycystic kidney disease 1 (autosomal dominant)		affects response to substance	ISO	16	2,138,711	2,185,899	RGD:6480464	CTD
G	PLCB1	phospholipase C, beta 1 (phosphoinositide-specific)		multiple interactions	ISO	20	8,113,296	8,865,547	RGD:6480464	CTD
G	PLCB1	phospholipase C, beta 1 (phosphoinositide-specific)		decreases expression	ISO	20	8,113,296	8,865,547	RGD:6480464	CTD
G	PLP1	proteolipid protein 1		increases expression	EXP	X	103,031,439	103,047,548	RGD:6480464	CTD
G	PNPLA8	patatin-like phospholipase domain containing 8		multiple interactions	ISO	7	108,110,866	108,168,605	RGD:6480464	CTD
G	POMC	proopiomelanocortin		increases secretion	ISO	2	25,383,722	25,391,559	RGD:6480464	CTD
G	PPM1B	protein phosphatase, Mg2+/Mn2+ dependent, 1B		multiple interactions	ISO	2	44,396,000	44,461,742	RGD:6480464	CTD
G	PPP2R2B	protein phosphatase 2, regulatory subunit B, beta		decreases expression	EXP	5	145,969,067	146,461,033	RGD:6480464	CTD
G	PPP2R3C	protein phosphatase 2, regulatory subunit B'', gamma		multiple interactions	ISO	14	35,554,678	35,591,519	RGD:6480464	CTD
G	PRELID1	PRELI domain containing 1		decreases expression	EXP	5	176,730,835	176,733,950	RGD:6480464	CTD
G	PRKAA2	protein kinase, AMP-activated, alpha 2 catalytic subunit		increases expression	ISO	1	57,110,990	57,181,008	RGD:6480464	CTD
G	PRKDC	protein kinase, DNA-activated, catalytic polypeptide		multiple interactions	EXP	8	48,685,669	48,872,743	RGD:6480464	CTD
G	PRKDC	protein kinase, DNA-activated, catalytic polypeptide		multiple interactions	ISO	8	48,685,669	48,872,743	RGD:6480464	CTD
G	PRNP	prion protein		decreases expression	EXP	20	4,666,797	4,682,234	RGD:6480464	CTD
G	PRORSD1P	prolyl-tRNA synthetase associated domain containing 1, pseudogene		decreases expression	ISO	2	55,509,455	55,511,608	RGD:6480464	CTD
G	PSMC5	proteasome (prosome, macropain) 26S subunit, ATPase, 5		multiple interactions	ISO	17	61,904,770	61,909,387	RGD:6480464	CTD
G	PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)		decreases expression	EXP	17	40,985,159	40,995,777	RGD:6480464	CTD
G	PTGFRN	prostaglandin F2 receptor inhibitor		increases expression	ISO	1	117,452,689	117,532,972	RGD:6480464	CTD
G	PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)		decreases expression	EXP	1	186,640,944	186,649,559	RGD:6480464	CTD
G	PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)		multiple interactions	ISO	1	186,640,944	186,649,559	RGD:6480464	CTD
G	PTPLA	protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A		decreases expression	ISO	10	17,631,958	17,659,373	RGD:6480464	CTD
G	PWP2	PWP2 periodic tryptophan protein homolog (yeast)		decreases expression	ISO	21	45,527,208	45,551,063	RGD:6480464	CTD
G	QRSL1	glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1		decreases expression	ISO	6	107,077,441	107,116,292	RGD:6480464	CTD
G	RAB3IP	RAB3A interacting protein		increases expression	ISO	12	70,132,631	70,216,984	RGD:6480464	CTD
G	RAB7A	RAB7A, member RAS oncogene family		multiple interactions	ISO	3	128,444,979	128,533,641	RGD:6480464	CTD
G	RABGEF1	RAB guanine nucleotide exchange factor (GEF) 1		decreases expression	ISO	7	66,205,643	66,276,451	RGD:6480464	CTD
G	RABL3	RAB, member of RAS oncogene family-like 3		decreases expression	ISO	3	120,405,528	120,461,384	RGD:6480464	CTD
G	RAD1	RAD1 homolog (S. pombe)		multiple interactions	ISO	5	34,905,365	34,915,780	RGD:6480464	CTD
G	RAD50	RAD50 homolog (S. cerevisiae)		multiple interactions	ISO	5	131,892,616	131,980,313	RGD:6480464	CTD
G	RAD51AP1	RAD51 associated protein 1		increases expression	ISO	12	4,647,950	4,669,213	RGD:6480464	CTD
G	RASA3	RAS p21 protein activator 3		multiple interactions	ISO	13	114,747,194	114,898,095	RGD:6480464	CTD
G	RASA3	RAS p21 protein activator 3		multiple interactions	ISO	13	114,747,194	114,898,095	RGD:6480464	CTD
G	RB1	retinoblastoma 1		decreases phosphorylation	ISO	13	48,877,883	49,056,026	RGD:6480464	CTD
G	RB1	retinoblastoma 1		decreases phosphorylation	EXP	13	48,877,883	49,056,026	RGD:6480464	CTD
G	RBBP4	retinoblastoma binding protein 4		multiple interactions	ISO	1	33,116,749	33,151,812	RGD:6480464	CTD
G	RBBP5	retinoblastoma binding protein 5		multiple interactions	ISO	1	205,055,270	205,091,150	RGD:6480464	CTD
G	RBM12	RNA binding motif protein 12		decreases expression	ISO	20	34,236,847	34,252,878	RGD:6480464	CTD
G	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)		multiple interactions	ISO	11	65,421,067	65,430,443	RGD:6480464	CTD
G	REN	renin		increases activity	ISO	1	204,123,944	204,135,465	RGD:6480464	CTD
G	REN	renin		increases expression	ISO	1	204,123,944	204,135,465	RGD:6480464	CTD
G	REN	renin		increases activity	EXP	1	204,123,944	204,135,465	RGD:6480464	CTD
G	REN	renin		increases activity	ISO	1	204,123,944	204,135,465	RGD:6480464	CTD
G	REN	renin		increases secretion	ISO	1	204,123,944	204,135,465	RGD:6480464	CTD
G	RGS2	regulator of G-protein signaling 2, 24kDa		multiple interactions	ISO	1	192,778,169	192,781,407	RGD:6480464	CTD
G	RHEBL1	Ras homolog enriched in brain like 1		increases expression	ISO	12	49,458,468	49,463,775	RGD:6480464	CTD
G	RIMS2	regulating synaptic membrane exocytosis 2		decreases expression	ISO	8	104,512,976	105,266,656	RGD:6480464	CTD
G	RNF166	ring finger protein 166		increases expression	ISO	16	88,762,903	88,772,829	RGD:6480464	CTD
G	RPIA	ribose 5-phosphate isomerase A		decreases expression	ISO	2	88,991,176	89,050,452	RGD:6480464	CTD
G	RPL26	ribosomal protein L26		multiple interactions	ISO	17	8,280,834	8,286,565	RGD:6480464	CTD
G	RPL5	ribosomal protein L5		multiple interactions	ISO	1	93,297,594	93,307,481	RGD:6480464	CTD
G	RPS6	ribosomal protein S6		decreases expression	ISO	9	19,376,254	19,380,235	RGD:6480464	CTD
G	RPS6	ribosomal protein S6		decreases expression	EXP	9	19,376,254	19,380,235	RGD:6480464	CTD
G	RPS6KA3	ribosomal protein S6 kinase, 90kDa, polypeptide 3		decreases expression	EXP	X	20,168,029	20,284,750	RGD:6480464	CTD
G	RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1		decreases expression	EXP	17	57,970,443	58,027,787	RGD:6480464	CTD
G	RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1		decreases expression	ISO	17	57,970,443	58,027,787	RGD:6480464	CTD
G	RRS1	RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)		increases expression	EXP	8	67,341,263	67,342,968	RGD:6480464	CTD
G	RSPO3	R-spondin 3		multiple interactions	ISO	6	127,440,048	127,518,184	RGD:6480464	CTD
G	RWDD2B	RWD domain containing 2B		decreases expression	ISO	21	30,378,080	30,391,685	RGD:6480464	CTD
G	RYR1	ryanodine receptor 1 (skeletal)		multiple interactions	ISO	19	38,924,340	39,078,204	RGD:6480464	CTD
G	RYR1	ryanodine receptor 1 (skeletal)		increases activity	ISO	19	38,924,340	39,078,204	RGD:6480464	CTD
G	RYR1	ryanodine receptor 1 (skeletal)		multiple interactions	EXP	19	38,924,340	39,078,204	RGD:6480464	CTD
G	RYR1	ryanodine receptor 1 (skeletal)		increases activity	EXP	19	38,924,340	39,078,204	RGD:6480464	CTD
G	RYR2	ryanodine receptor 2 (cardiac)		multiple interactions	ISO	1	237,205,702	237,997,288	RGD:6480464	CTD
G	RYR2	ryanodine receptor 2 (cardiac)		multiple interactions	ISO	1	237,205,702	237,997,288	RGD:6480464	CTD
G	SAP18	Sin3A-associated protein, 18kDa		multiple interactions	ISO	13	21,714,653	21,723,224	RGD:6480464	CTD
G	SCFD1	sec1 family domain containing 1		decreases expression	EXP	14	31,091,460	31,205,034	RGD:6480464	CTD
G	SEC13	SEC13 homolog (S. cerevisiae)		decreases expression	EXP	3	10,342,615	10,362,858	RGD:6480464	CTD
G	SEC23A	Sec23 homolog A (S. cerevisiae)		decreases expression	EXP	14	39,501,123	39,572,437	RGD:6480464	CTD
G	SENP6	SUMO1/sentrin specific peptidase 6		multiple interactions	ISO	6	76,311,622	76,427,997	RGD:6480464	CTD
G	SEPT7	septin 7		multiple interactions	ISO	7	35,840,596	35,946,715	RGD:6480464	CTD
G	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1		increases expression	EXP	14	94,843,084	94,857,029	RGD:6480464	CTD
G	SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6		decreases expression	EXP	14	94,770,585	94,789,688	RGD:6480464	CTD
G	SFPQ	splicing factor proline/glutamine-rich		multiple interactions	ISO	1	35,649,201	35,658,743	RGD:6480464	CTD
G	SHARPIN	SHANK-associated RH domain interactor		increases expression	ISO	8	145,153,536	145,159,140	RGD:6480464	CTD
G	SIGMAR1	sigma non-opioid intracellular receptor 1		decreases expression	ISO	9	34,634,719	34,637,768	RGD:6480464	CTD
G	SLC16A1	solute carrier family 16, member 1 (monocarboxylic acid transporter 1)		multiple interactions	EXP	1	113,454,469	113,498,975	RGD:6480464	CTD
G	SLC16A1	solute carrier family 16, member 1 (monocarboxylic acid transporter 1)		increases expression	EXP	1	113,454,469	113,498,975	RGD:6480464	CTD
G	SLC17A5	solute carrier family 17 (anion/sugar transporter), member 5		increases expression	ISO	6	74,303,102	74,363,737	RGD:6480464	CTD
G	SLC24A6	solute carrier family 24 (sodium/lithium/calcium exchanger), member 6		increases expression	ISO	12	113,736,571	113,772,925	RGD:6480464	CTD
G	SLC25A37	solute carrier family 25 (mitochondrial iron transporter), member 37		decreases expression	ISO	8	23,386,363	23,430,063	RGD:6480464	CTD
G	SLC30A7	solute carrier family 30 (zinc transporter), member 7		decreases expression	ISO	1	101,361,632	101,447,311	RGD:6480464	CTD
G	SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3		increases response to substance	ISO	5	1,392,905	1,445,543	RGD:6480464	CTD
G	SMAD1	SMAD family member 1		multiple interactions	ISO	4	146,402,951	146,480,328	RGD:6480464	CTD
G	SMAD3	SMAD family member 3		multiple interactions	ISO	15	67,358,195	67,487,533	RGD:6480464	CTD
G	SMOX	spermine oxidase		increases expression	EXP	20	4,129,426	4,168,394	RGD:6480464	CTD
G	SMPD3	sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)		multiple interactions	ISO	16	68,392,230	68,482,409	RGD:6480464	CTD
G	SNX3	sorting nexin 3		increases expression	ISO	6	108,532,717	108,582,464	RGD:6480464	CTD
G	SQLE	squalene epoxidase		decreases expression	ISO	8	126,010,720	126,034,525	RGD:6480464	CTD
G	SQLE	squalene epoxidase		decreases expression	EXP	8	126,010,720	126,034,525	RGD:6480464	CTD
G	SQSTM1	sequestosome 1		increases expression	ISO	5	179,233,388	179,265,078	RGD:6480464	CTD
G	SQSTM1	sequestosome 1		decreases expression	EXP	5	179,233,388	179,265,078	RGD:6480464	CTD
G	SRP9	signal recognition particle 9kDa		multiple interactions	ISO	1	225,965,515	225,978,168	RGD:6480464	CTD
G	SRSF1	serine/arginine-rich splicing factor 1		decreases expression	EXP	17	56,078,280	56,084,707	RGD:6480464	CTD
G	STAR	steroidogenic acute regulatory protein		increases expression	EXP	8	38,000,218	38,008,600	RGD:6480464	CTD
G	STAR	steroidogenic acute regulatory protein		decreases methylation	EXP	8	38,000,218	38,008,600	RGD:6480464	CTD
G	STARD4	StAR-related lipid transfer (START) domain containing 4		decreases expression	ISO	5	110,834,022	110,848,157	RGD:6480464	CTD
G	STIM1	stromal interaction molecule 1		increases expression	ISO	11	3,876,933	4,114,440	RGD:6480464	CTD
G	STIP1	stress-induced-phosphoprotein 1		multiple interactions	ISO	11	63,953,587	63,972,020	RGD:6480464	CTD
G	STMN1	stathmin 1		increases expression	ISO	1	26,210,677	26,233,368	RGD:6480464	CTD
G	STRBP	spermatid perinuclear RNA binding protein		decreases expression	EXP	9	125,883,899	126,030,855	RGD:6480464	CTD
G	STX4	syntaxin 4		multiple interactions	ISO	16	31,044,903	31,051,485	RGD:6480464	CTD
G	SYT4	synaptotagmin IV		multiple interactions	ISO	18	40,847,857	40,857,615	RGD:6480464	CTD
G	TAF1D	TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa		decreases expression	ISO	11	93,469,095	93,474,703	RGD:6480464	CTD
G	TBRG4	transforming growth factor beta regulator 4		decreases expression	ISO	7	45,139,699	45,151,346	RGD:6480464	CTD
G	TDO2	tryptophan 2,3-dioxygenase		increases activity	ISO	4	156,824,845	156,841,558	RGD:6480464	CTD
G	TFDP1	transcription factor Dp-1		decreases expression	EXP	13	114,239,003	114,295,788	RGD:6480464	CTD
G	TFRC	transferrin receptor (p90, CD71)		multiple interactions	ISO	3	195,776,155	195,809,032	RGD:6480464	CTD
G	TH	tyrosine hydroxylase		multiple interactions	ISO	11	2,185,159	2,193,035	RGD:6480464	CTD
G	TH	tyrosine hydroxylase		multiple interactions	ISO	11	2,185,159	2,193,035	RGD:6480464	CTD
G	TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein		multiple interactions	ISO	11	126,152,982	126,164,828	RGD:6480464	CTD
G	TLCD1	TLC domain containing 1		decreases expression	ISO	17	27,051,366	27,053,949	RGD:6480464	CTD
G	TM9SF1	transmembrane 9 superfamily member 1		decreases expression	EXP	14	24,658,353	24,664,882	RGD:6480464	CTD
G	TMCC2	transmembrane and coiled-coil domain family 2		increases expression	EXP	1	205,197,038	205,242,471	RGD:6480464	CTD
G	TMED5	transmembrane emp24 protein transport domain containing 5		decreases expression	ISO	1	93,615,299	93,646,246	RGD:6480464	CTD
G	TMEM69	transmembrane protein 69		decreases expression	ISO	1	46,153,847	46,160,108	RGD:6480464	CTD
G	TMEM97	transmembrane protein 97		decreases expression	EXP	17	26,646,121	26,655,711	RGD:6480464	CTD
G	TNF	tumor necrosis factor		multiple interactions	ISO	6	31,543,344	31,546,113	RGD:6480464	CTD
G	TNFRSF19	tumor necrosis factor receptor superfamily, member 19		increases expression	ISO	13	24,144,509	24,250,244	RGD:6480464	CTD
G	TNFSF4	tumor necrosis factor (ligand) superfamily, member 4		increases expression	EXP	1	173,152,870	173,176,471	RGD:6480464	CTD
G	TNK2	tyrosine kinase, non-receptor, 2		multiple interactions	ISO	3	195,590,236	195,635,880	RGD:6480464	CTD
G	TNKS2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2		increases expression	ISO	10	93,558,151	93,625,232	RGD:6480464	CTD
G	TP53	tumor protein p53		multiple interactions	EXP	17	7,571,720	7,590,868	RGD:6480464	CTD
G	TP53	tumor protein p53		multiple interactions	EXP	17	7,571,720	7,590,868	RGD:6480464	CTD
G	TP53	tumor protein p53		multiple interactions	EXP	17	7,571,720	7,590,868	RGD:6480464	CTD
G	TP53	tumor protein p53		multiple interactions	EXP	17	7,571,720	7,590,868	RGD:6480464	CTD
G	TP53	tumor protein p53		multiple interactions	EXP	17	7,571,720	7,590,868	RGD:6480464	CTD
G	TP53	tumor protein p53		multiple interactions	EXP	17	7,571,720	7,590,868	RGD:6480464	CTD
G	TP53	tumor protein p53		multiple interactions	EXP	17	7,571,720	7,590,868	RGD:6480464	CTD
G	TP53	tumor protein p53		increases phosphorylation	EXP	17	7,571,720	7,590,868	RGD:6480464	CTD
G	TP53	tumor protein p53		multiple interactions	ISO	17	7,571,720	7,590,868	RGD:6480464	CTD
G	TP53	tumor protein p53		decreases mutagenesis	ISO	17	7,571,720	7,590,868	RGD:6480464	CTD
G	TP53	tumor protein p53		multiple interactions	ISO	17	7,571,720	7,590,868	RGD:6480464	CTD
G	TPH2	tryptophan hydroxylase 2		multiple interactions	ISO	12	72,332,626	72,426,221	RGD:6480464	CTD
G	TPP2	tripeptidyl peptidase II		multiple interactions	ISO	13	103,249,286	103,331,524	RGD:6480464	CTD
G	TPRA1	transmembrane protein, adipocyte asscociated 1		increases expression	ISO	3	127,291,908	127,309,568	RGD:6480464	CTD
G	TRPC3	transient receptor potential cation channel, subfamily C, member 3		multiple interactions	ISO	4	122,800,183	122,872,909	RGD:6480464	CTD
G	TSC22D1	TSC22 domain family, member 1		multiple interactions	ISO	13	45,006,279	45,150,701	RGD:6480464	CTD
G	TXNRD1	thioredoxin reductase 1		decreases expression	EXP	12	104,609,557	104,744,085	RGD:6480464	CTD
G	TYMS	thymidylate synthetase		decreases expression	ISO	18	657,604	673,499	RGD:6480464	CTD
G	TYW5	tRNA-yW synthesizing protein 5		decreases expression	ISO	2	200,793,634	200,820,459	RGD:6480464	CTD
G	UBB	ubiquitin B		multiple interactions	ISO	17	16,284,367	16,286,054	RGD:6480464	CTD
G	UBC	ubiquitin C		multiple interactions	ISO	12	125,396,192	125,399,587	RGD:6480464	CTD
G	UBE2D2	ubiquitin-conjugating enzyme E2D 2		multiple interactions	ISO	5	138,940,751	139,008,019	RGD:6480464	CTD
G	UBIAD1	UbiA prenyltransferase domain containing 1		decreases expression	ISO	1	11,333,255	11,348,491	RGD:6480464	CTD
G	UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)		multiple interactions	ISO	4	41,258,898	41,270,446	RGD:6480464	CTD
G	UGT1A1	UDP glucuronosyltransferase 1 family, polypeptide A1		increases expression	EXP	2	234,668,919	234,681,945	RGD:6480464	CTD
G	UQCRC2	ubiquinol-cytochrome c reductase core protein II		decreases expression	EXP	16	21,964,609	21,994,668	RGD:6480464	CTD
G	UROS	uroporphyrinogen III synthase		multiple interactions	ISO	10	127,477,147	127,511,837	RGD:6480464	CTD
G	USP11	ubiquitin specific peptidase 11		increases expression	ISO	X	47,092,314	47,107,727	RGD:6480464	CTD
G	UTP18	UTP18 small subunit (SSU) processome component homolog (yeast)		decreases expression	ISO	17	49,337,897	49,375,294	RGD:6480464	CTD
G	VEGFA	vascular endothelial growth factor A		increases expression	ISO	6	43,737,946	43,754,224	RGD:6480464	CTD
G	VPS41	vacuolar protein sorting 41 homolog (S. cerevisiae)		multiple interactions	ISO	7	38,763,543	38,948,800	RGD:6480464	CTD
G	WBP4	WW domain binding protein 4		multiple interactions	ISO	13	41,635,697	41,658,139	RGD:6480464	CTD
G	WDR43	WD repeat domain 43		decreases expression	ISO	2	29,117,533	29,171,080	RGD:6480464	CTD
G	WNT4	wingless-type MMTV integration site family, member 4		affects expression	ISO	1	22,443,798	22,469,519	RGD:6480464	CTD
G	XDH	xanthine dehydrogenase		affects metabolic processing	EXP	2	31,557,188	31,637,611	RGD:6480464	CTD
G	XDH	xanthine dehydrogenase		affects metabolic processing	EXP	2	31,557,188	31,637,611	RGD:6480464	CTD
G	XDH	xanthine dehydrogenase		affects metabolic processing	EXP	2	31,557,188	31,637,611	RGD:6480464	CTD
G	XDH	xanthine dehydrogenase		affects metabolic processing	EXP	2	31,557,188	31,637,611	RGD:6480464	CTD
G	XDH	xanthine dehydrogenase		affects metabolic processing	EXP	2	31,557,188	31,637,611	RGD:6480464	CTD
G	XDH	xanthine dehydrogenase		affects metabolic processing	EXP	2	31,557,188	31,637,611	RGD:6480464	CTD
G	XDH	xanthine dehydrogenase		affects metabolic processing	EXP	2	31,557,188	31,637,611	RGD:6480464	CTD
G	XKR5	XK, Kell blood group complex subunit-related family, member 5		decreases expression	ISO	8	6,666,038	6,693,166	RGD:6480464	CTD
G	YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide		multiple interactions	EXP	2	9,724,106	9,771,106	RGD:6480464	CTD
G	ZNF175	zinc finger protein 175		decreases expression	ISO	19	52,074,531	52,092,991	RGD:6480464	CTD
G	ZNF276	zinc finger protein 276		decreases expression	ISO	16	89,787,393	89,807,333	RGD:6480464	CTD
G	ZNF37A	zinc finger protein 37A		increases expression	EXP	10	38,383,264	38,412,280	RGD:6480464	CTD
G	ZNF553	zinc finger protein 553		decreases expression	ISO				RGD:6480464	CTD

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	513696
role	503218
biological role	501391
aetiopathogenetic role	112044
mutagen	19156
caffeine	578
8-(3-chlorostyryl)caffeine	0
caffeine monohydrate	0
Path 2
Term	Annotations
CHEBI ontology	513696
subatomic particle	512589
composite particle	512589
hadron	512589
baryon	512589
nucleon	512589
atomic nucleus	512589
atom	512589
main group element atom	480600
p-block element atom	478018
carbon group element atom	427607
carbon atom	424015
organic molecular entity	424008
organic molecule	311307
organic cyclic compound	311226
organic heterocyclic compound	160187
organic heteropolycyclic compound	99800
organic heterobicyclic compound	59826
imidazopyrimidine	4619
purines	4619
oxopurine	2045
xanthine	1689
methylxanthine	1213
trimethylxanthine	578
caffeine	578
8-(3-chlorostyryl)caffeine	0
caffeine monohydrate	0