oxytetracycline - Ontology Report

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ONTOLOGY REPORT - ANNOTATIONS

Term:	oxytetracycline	go back to main search page
Accession:	CHEBI:27701	browse the term
Definition:	A tetracycline used for treatment of infections caused by a variety of Gram positive and Gram negative microorganisms including Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae (respiratory infections), and Diplococcus pneumoniae.
Synonyms:	exact_synonym:	(4S,4aR,5S,5aR,6S,12aS)-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
	related_synonym:	5-Hydroxytetracycline; C22H24N2O9; InChI=1S/C22H24N2O9/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29/h4-6,12-14,17,25,27-29,32-33H,1-3H3,(H2,23,31)/t12-,13-,14+,17+,21-,22+/m1/s1; InChIKey=IWVCMVBTMGNXQD-PXOLEDIWSA-N; Oxyterracin; Oxyterracine; Oxytetracyclin; Oxytetracycline (anhydrous); Oxytetracycline amphoteric; [H][C@@]12[C@@H](O)[C@@]3([H])C(C(=O)c4c(O)cccc4[C@@]3(C)O)=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C; oxitetraciclina; oxytetracyclinum
	alt_id:	CHEBI:25811; CHEBI:521157; CHEBI:596903; CHEBI:7871
	xref_casrn:	79-57-2
	xref:	Beilstein:2686362 "Beilstein Registry Number"; Beilstein:2714587 "Beilstein Registry Number"; ChEBI:LMPK07000005 "LIPID MAPS instance"; ChEMBL:17638695 "PubMed citation"; ChEMBL:17870541 "PubMed citation"; ChEMBL:521157 "ChEMBL COMPOUND"; ChEMBL:596903 "ChEMBL COMPOUND"; ChemIDplus:79-57-2 "CAS Registry Number"; CiteXplore:1650428 "PubMed citation"; DrugBank:DB00595 "DrugBank"; Gmelin:623487 "Gmelin Registry Number"; KEGG COMPOUND:79-57-2 "CAS Registry Number"; KEGG COMPOUND:C06624 "KEGG COMPOUND"
	xref_mesh:	MESH:D010118
	xref:	Reaxys:2714587 "Reaxys Registry Number"; Wikipedia:Oxytetracycline "Wikipedia"

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oxytetracycline
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	CCL2	chemokine (C-C motif) ligand 2		decreases expression	EXP	17	32,582,296	32,584,222	RGD:6480464	CTD
G	CCL3	chemokine (C-C motif) ligand 3		decreases expression	EXP	17	34,415,602	34,417,506	RGD:6480464	CTD
G	CCL4	chemokine (C-C motif) ligand 4		decreases expression	EXP	17	34,431,220	34,433,014	RGD:6480464	CTD
G	CCL5	chemokine (C-C motif) ligand 5		decreases expression	EXP	17	34,198,495	34,207,377	RGD:6480464	CTD
G	IL6R	interleukin 6 receptor		decreases expression	EXP	1	154,377,669	154,441,926	RGD:6480464	CTD
G	IL8	interleukin 8		decreases expression	EXP	4	74,606,223	74,609,433	RGD:6480464	CTD
G	SLC22A6	solute carrier family 22 (organic anion transporter), member 6		multiple interactions	EXP	11	62,744,069	62,752,495	RGD:6480464	CTD
G	SLC22A7	solute carrier family 22 (organic anion transporter), member 7		multiple interactions	EXP	6	43,265,998	43,273,276	RGD:6480464	CTD
G	VEGFA	vascular endothelial growth factor A		decreases expression	EXP	6	43,737,946	43,754,224	RGD:6480464	CTD

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	513708
role	503229
biological role	501402
antimicrobial agent	47908
antibacterial agent	16550
antibacterial drug	4219
oxytetracycline	9
Path 2
Term	Annotations
CHEBI ontology	513708
subatomic particle	512601
composite particle	512601
hadron	512601
baryon	512601
nucleon	512601
atomic nucleus	512601
atom	512601
main group element atom	480609
main group molecular entity	475261
s-block molecular entity	323985
hydrogen molecular entity	321181
hydrides	200531
organic hydride	123086
organic fundamental parent	123086
hydrocarbon	73806
cyclic hydrocarbon	38701
arene	38025
polycyclic arene	34560
ortho-fused polycyclic arene	7838
acene	4624
tetracene	4595
tetracyclines	535
oxytetracycline	9