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Term:camptothecin
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Accession:CHEBI:27656 term browser browse the term
Definition:A pyranoindolizinoquinoline that has formula C20H16N2O4.
Synonyms:exact_synonym: (4S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
 related_synonym: (S)-(+)-camptothecin;   20(S)-camptothecine;   21,22-Secocamptothecin-21-oic acid lactone;   C20H16N2O4;   CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4ccccc4cc3Cn1c2=O;   CPT;   Camptothecine;   D-camptothecin;   InChI=1S/C20H16N2O4/c1-2-20(25)14-8-16-17-12(7-11-5-3-4-6-15(11)21-17)9-22(16)18(23)13(14)10-26-19(20)24/h3-8,25H,2,9-10H2,1H3/t20-/m0/s1;   InChIKey=VSJKWCGYPAHWDS-FQEVSTJZSA-N
 alt_id: CHEBI:22997;   CHEBI:3343
 xref_casrn: 7689-03-4
 xref: Beilstein:6075662 "Beilstein Registry Number";   ChEMBL:105105 "ChEMBL COMPOUND";   ChemIDplus:7689-03-4 "CAS Registry Number";   DrugBank:DB04690 "DrugBank";   KEGG COMPOUND:C01897 "KEGG COMPOUND"
 xref_mesh: MESH:D002166

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Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link decreases expression ISO 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 GBrowse link decreases response to substance ISO 10 452,239 575,705 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 GBrowse link multiple interactions ISO 10 452,239 575,705 RGD:6480464 CTD
G Agrn agrin GBrowse link increases expression ISO 5 172,999,420 173,020,764 RGD:6480464 CTD
G Alb albumin GBrowse link affects binding ISO 14 19,126,935 19,142,214 RGD:6480464 CTD
G Alb albumin GBrowse link affects binding ISO 14 19,126,935 19,142,214 RGD:6480464 CTD
G Alb albumin GBrowse link multiple interactions ISO 14 19,126,935 19,142,214 RGD:6480464 CTD
G Anxa4 annexin A4 GBrowse link increases expression ISO 4 120,889,617 120,947,662 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link multiple interactions ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link increases activity ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link increases expression ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link increases expression EXP 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link multiple interactions EXP 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link decreases expression ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link multiple interactions ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link decreases response to substance ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link decreases expression ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link decreases expression ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2l1 Bcl2-like 1 GBrowse link decreases response to substance EXP 3 143,129,087 143,180,199 RGD:6480464 CTD
G Bcl2l1 Bcl2-like 1 GBrowse link decreases expression EXP 3 143,129,087 143,180,199 RGD:6480464 CTD
G Bcl2l1 Bcl2-like 1 GBrowse link increases expression EXP 3 143,129,087 143,180,199 RGD:6480464 CTD
G Bcl2l1 Bcl2-like 1 GBrowse link multiple interactions EXP 3 143,129,087 143,180,199 RGD:6480464 CTD
G Bcl2l1 Bcl2-like 1 GBrowse link multiple interactions EXP 3 143,129,087 143,180,199 RGD:6480464 CTD
G Bid BH3 interacting domain death agonist GBrowse link multiple interactions ISO 4 157,296,383 157,318,481 RGD:6480464 CTD
G Bid BH3 interacting domain death agonist GBrowse link multiple interactions ISO 4 157,296,383 157,318,481 RGD:6480464 CTD
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO RGD:6480464 CTD
G Brca1 breast cancer 1, early onset GBrowse link decreases expression ISO 10 90,513,630 90,572,676 RGD:6480464 CTD
G Brca2 breast cancer 2, early onset GBrowse link decreases expression ISO 12 4,282,952 4,323,693 RGD:6480464 CTD
G Bscl2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) GBrowse link increases expression ISO 1 211,509,675 211,518,963 RGD:6480464 CTD
G Cab39 calcium binding protein 39 GBrowse link decreases expression ISO 9 84,528,678 84,590,375 RGD:6480464 CTD
G Casp2 caspase 2 GBrowse link increases splicing ISO 4 70,029,728 70,047,164 RGD:6480464 CTD
G Casp2 caspase 2 GBrowse link increases expression ISO 4 70,029,728 70,047,164 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases cleavage ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases cleavage EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases cleavage ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases cleavage ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp8 caspase 8 GBrowse link multiple interactions ISO 9 57,389,353 57,437,803 RGD:6480464 CTD
G Casp8 caspase 8 GBrowse link multiple interactions ISO 9 57,389,353 57,437,803 RGD:6480464 CTD
G Casp8 caspase 8 GBrowse link affects cleavage ISO 9 57,389,353 57,437,803 RGD:6480464 CTD
G Casp8 caspase 8 GBrowse link multiple interactions ISO 9 57,389,353 57,437,803 RGD:6480464 CTD
G Casp8 caspase 8 GBrowse link increases activity ISO 9 57,389,353 57,437,803 RGD:6480464 CTD
G Casp8 caspase 8 GBrowse link multiple interactions EXP 9 57,389,353 57,437,803 RGD:6480464 CTD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link multiple interactions ISO 5 160,704,234 160,721,796 RGD:6480464 CTD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link multiple interactions ISO 5 160,704,234 160,721,796 RGD:6480464 CTD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link increases cleavage ISO 5 160,704,234 160,721,796 RGD:6480464 CTD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link multiple interactions EXP 5 160,704,234 160,721,796 RGD:6480464 CTD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link increases activity EXP 5 160,704,234 160,721,796 RGD:6480464 CTD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link multiple interactions EXP 5 160,704,234 160,721,796 RGD:6480464 CTD
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link decreases expression ISO 10 70,256,263 70,258,061 RGD:6480464 CTD
G Ccl4 chemokine (C-C motif) ligand 4 GBrowse link decreases expression ISO 10 71,759,643 71,761,115 RGD:6480464 CTD
G Ccl5 chemokine (C-C motif) ligand 5 GBrowse link decreases expression ISO 10 71,605,791 71,610,330 RGD:6480464 CTD
G Ccnb1 cyclin B1 GBrowse link multiple interactions ISO 2 31,574,600 31,581,784 RGD:6480464 CTD
G Ccnd1 cyclin D1 GBrowse link affects localization ISO 1 205,357,235 205,366,757 RGD:6480464 CTD
G Cdk2 cyclin dependent kinase 2 GBrowse link multiple interactions ISO 7 2,000,196 2,007,682 RGD:6480464 CTD
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link increases expression ISO 20 7,376,325 7,386,778 RGD:6480464 CTD
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link multiple interactions ISO 20 7,376,325 7,386,778 RGD:6480464 CTD
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link increases expression ISO 20 7,376,325 7,386,778 RGD:6480464 CTD
G Ceacam1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) GBrowse link increases expression ISO 1 80,742,540 80,758,943 RGD:6480464 CTD
G Cebpz CCAAT/enhancer binding protein zeta GBrowse link decreases expression ISO 6 1,698,162 1,715,846 RGD:6480464 CTD
G Crebbp CREB binding protein GBrowse link multiple interactions EXP 10 11,598,680 11,724,122 RGD:6480464 CTD
G Ctsb cathepsin B GBrowse link multiple interactions ISO 15 42,402,829 42,423,701 RGD:6480464 CTD
G Cycs cytochrome c, somatic GBrowse link multiple interactions ISO 4 78,825,878 78,827,978 RGD:6480464 CTD
G Cycs cytochrome c, somatic GBrowse link affects localization ISO 4 78,825,878 78,827,978 RGD:6480464 CTD
G Dpyd dihydropyrimidine dehydrogenase GBrowse link multiple interactions ISO 2 214,931,901 215,818,809 RGD:6480464 CTD
G Dpyd dihydropyrimidine dehydrogenase GBrowse link decreases expression ISO 2 214,931,901 215,818,809 RGD:6480464 CTD
G Dpyd dihydropyrimidine dehydrogenase GBrowse link decreases activity ISO 2 214,931,901 215,818,809 RGD:6480464 CTD
G Ei24 etoposide induced 2.4 GBrowse link increases expression ISO 8 38,028,043 38,044,316 RGD:6480464 CTD
G Ep300 E1A binding protein p300 GBrowse link decreases expression ISO 7 119,938,507 120,008,886 RGD:6480464 CTD
G Epm2aip1 EPM2A (laforin) interacting protein 1 GBrowse link increases expression ISO 8 115,653,794 115,656,867 RGD:6480464 CTD
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 GBrowse link multiple interactions ISO 1 78,711,249 78,722,474 RGD:6480464 CTD
G Ercc4 excision repair cross-complementing rodent repair deficiency, complementation group 4 GBrowse link multiple interactions ISO 10 2,144,262 2,177,554 RGD:6480464 CTD
G Ercc4 excision repair cross-complementing rodent repair deficiency, complementation group 4 GBrowse link decreases response to substance ISO 10 2,144,262 2,177,554 RGD:6480464 CTD
G Fas Fas cell surface death receptor GBrowse link multiple interactions ISO 1 238,259,443 238,274,745 RGD:6480464 CTD
G Fas Fas cell surface death receptor GBrowse link multiple interactions ISO 1 238,259,443 238,274,745 RGD:6480464 CTD
G Fas Fas cell surface death receptor GBrowse link multiple interactions ISO 1 238,259,443 238,274,745 RGD:6480464 CTD
G Fdxr ferredoxin reductase GBrowse link increases expression ISO 10 105,342,684 105,351,374 RGD:6480464 CTD
G Fxn frataxin GBrowse link increases expression ISO 1 227,647,092 227,671,081 RGD:6480464 CTD
G Gstp1 glutathione S-transferase pi 1 GBrowse link increases expression ISO 1 206,627,398 206,629,866 RGD:6480464 CTD
G Gstp1 glutathione S-transferase pi 1 GBrowse link decreases response to substance ISO 1 206,627,398 206,629,866 RGD:6480464 CTD
G Gstp1 glutathione S-transferase pi 1 GBrowse link decreases response to substance ISO 1 206,627,398 206,629,866 RGD:6480464 CTD
G Gstp1 glutathione S-transferase pi 1 GBrowse link decreases response to substance ISO 1 206,627,398 206,629,866 RGD:6480464 CTD
G H2afx H2A histone family, member X GBrowse link multiple interactions ISO 8 47,312,609 47,313,938 RGD:6480464 CTD
G H2afx H2A histone family, member X GBrowse link increases expression ISO 8 47,312,609 47,313,938 RGD:6480464 CTD
G H2afx H2A histone family, member X GBrowse link increases expression EXP 8 47,312,609 47,313,938 RGD:6480464 CTD
G H2afx H2A histone family, member X GBrowse link increases expression ISO 8 47,312,609 47,313,938 RGD:6480464 CTD
G H2afx H2A histone family, member X GBrowse link multiple interactions ISO 8 47,312,609 47,313,938 RGD:6480464 CTD
G Hnrnpc heterogeneous nuclear ribonucleoprotein C (C1/C2) GBrowse link multiple interactions ISO 15 27,516,839 27,546,646 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link decreases response to substance ISO 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il6r interleukin 6 receptor GBrowse link decreases expression ISO 2 182,078,049 182,128,135 RGD:6480464 CTD
G Jun jun proto-oncogene GBrowse link increases expression ISO 5 115,358,166 115,361,259 RGD:6480464 CTD
G Jun jun proto-oncogene GBrowse link increases phosphorylation ISO 5 115,358,166 115,361,259 RGD:6480464 CTD
G Lgals1 lectin, galactoside-binding, soluble, 1 GBrowse link decreases expression ISO 7 116,893,662 116,896,768 RGD:6480464 CTD
G Map2k3 mitogen activated protein kinase kinase 3 GBrowse link increases expression ISO 10 47,075,270 47,096,617 RGD:6480464 CTD
G Map3k5 mitogen-activated protein kinase kinase kinase 5 GBrowse link decreases expression ISO 1 15,205,361 15,346,422 RGD:6480464 CTD
G Mapk9 mitogen-activated protein kinase 9 GBrowse link increases phosphorylation ISO 10 35,353,486 35,384,319 RGD:6480464 CTD
G Mapt microtubule-associated protein tau GBrowse link decreases expression ISO 10 93,411,098 93,508,762 RGD:6480464 CTD
G Mdm2 p53 E3 ubiquitin protein ligase GBrowse link increases expression ISO 7 56,996,694 57,020,926 RGD:6480464 CTD
G Mgmt O-6-methylguanine-DNA methyltransferase GBrowse link decreases expression ISO 1 196,629,366 196,866,937 RGD:6480464 CTD
G Nck2 NCK adaptor protein 2 GBrowse link decreases expression ISO 9 42,650,261 42,776,967 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link increases cleavage ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link increases cleavage ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link multiple interactions ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link multiple interactions ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link increases cleavage ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link multiple interactions ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link increases cleavage ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link increases cleavage ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link increases cleavage ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link increases cleavage ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link increases cleavage ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Plk3 polo-like kinase 3 GBrowse link increases expression ISO 5 137,443,540 137,448,715 RGD:6480464 CTD
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B GBrowse link decreases response to substance ISO 10 87,121,889 87,131,587 RGD:6480464 CTD
G Prc1 protein regulator of cytokinesis 1 GBrowse link decreases expression ISO 1 136,112,674 136,133,720 RGD:6480464 CTD
G Rad51 RAD51 homolog (S. cerevisiae) GBrowse link decreases expression ISO 3 105,625,265 105,650,392 RGD:6480464 CTD
G Rad51c Rad51 homolog c (S. cerevisiae) GBrowse link increases response to substance ISO 10 75,692,205 75,718,369 RGD:6480464 CTD
G Rb1 retinoblastoma 1 GBrowse link increases phosphorylation ISO 15 53,828,881 53,962,099 RGD:6480464 CTD
G Rb1 retinoblastoma 1 GBrowse link affects response to substance ISO 15 53,828,881 53,962,099 RGD:6480464 CTD
G Rb1 retinoblastoma 1 GBrowse link increases phosphorylation ISO 15 53,828,881 53,962,099 RGD:6480464 CTD
G Rb1 retinoblastoma 1 GBrowse link affects response to substance ISO 15 53,828,881 53,962,099 RGD:6480464 CTD
G Rbl1 retinoblastoma-like 1 (p107) GBrowse link decreases expression ISO 3 147,734,622 147,796,630 RGD:6480464 CTD
G Rbl2 retinoblastoma-like 2 GBrowse link multiple interactions ISO 19 17,045,131 17,092,597 RGD:6480464 CTD
G Rbl2 retinoblastoma-like 2 GBrowse link decreases response to substance ISO 19 17,045,131 17,092,597 RGD:6480464 CTD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link increases response to substance ISO 1 208,262,669 208,273,148 RGD:6480464 CTD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link multiple interactions EXP 1 208,262,669 208,273,148 RGD:6480464 CTD
G Ret ret proto-oncogene GBrowse link decreases expression EXP 4 154,448,179 154,491,103 RGD:6480464 CTD
G Sdc1 syndecan 1 GBrowse link increases expression ISO 6 32,253,352 32,275,812 RGD:6480464 CTD
G Smn1 survival of motor neuron 1, telomeric GBrowse link multiple interactions ISO 2 31,147,743 31,159,938 RGD:6480464 CTD
G Smn1 survival of motor neuron 1, telomeric GBrowse link increases response to substance ISO 2 31,147,743 31,159,938 RGD:6480464 CTD
G Smpd3 sphingomyelin phosphodiesterase 3, neutral membrane GBrowse link increases expression ISO 19 36,112,166 36,195,564 RGD:6480464 CTD
G Sp1 Sp1 transcription factor GBrowse link multiple interactions ISO 7 141,164,180 141,194,509 RGD:6480464 CTD
G Sp1 Sp1 transcription factor GBrowse link increases activity ISO 7 141,164,180 141,194,509 RGD:6480464 CTD
G Sp3 Sp3 transcription factor GBrowse link increases activity ISO 3 55,440,985 55,485,768 RGD:6480464 CTD
G Sp3 Sp3 transcription factor GBrowse link multiple interactions ISO 3 55,440,985 55,485,768 RGD:6480464 CTD
G Srxn1 sulfiredoxin 1 GBrowse link increases expression ISO 3 142,457,352 142,462,725 RGD:6480464 CTD
G Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) GBrowse link increases expression ISO 20 4,790,363 4,800,730 RGD:6480464 CTD
G Tdp1 tyrosyl-DNA phosphodiesterase 1 GBrowse link multiple interactions ISO 6 124,095,259 124,162,815 RGD:6480464 CTD
G Thbs1 thrombospondin 1 decreases expression ISO RGD:6480464 CTD
G Thbs1 thrombospondin 1 multiple interactions ISO RGD:6480464 CTD
G Thbs1 thrombospondin 1 decreases secretion ISO RGD:6480464 CTD
G Tnfsf9 tumor necrosis factor (ligand) superfamily, member 9 increases expression ISO RGD:6480464 CTD
G Top1 topoisomerase (DNA) I GBrowse link multiple interactions ISO 3 151,428,931 151,512,884 RGD:6480464 CTD
G Top1 topoisomerase (DNA) I GBrowse link decreases activity ISO 3 151,428,931 151,512,884 RGD:6480464 CTD
G Top1 topoisomerase (DNA) I GBrowse link decreases response to substance ISO 3 151,428,931 151,512,884 RGD:6480464 CTD
G Top1 topoisomerase (DNA) I GBrowse link decreases activity ISO 3 151,428,931 151,512,884 RGD:6480464 CTD
G Top1 topoisomerase (DNA) I GBrowse link decreases activity ISO 3 151,428,931 151,512,884 RGD:6480464 CTD
G Top1 topoisomerase (DNA) I GBrowse link decreases activity ISO 3 151,428,931 151,512,884 RGD:6480464 CTD
G Top1 topoisomerase (DNA) I GBrowse link decreases activity EXP 3 151,428,931 151,512,884 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases expression ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases activity EXP 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link multiple interactions EXP 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases expression ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link multiple interactions ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link multiple interactions ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases expression ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases phosphorylation ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases glutathionylation ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link multiple interactions ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases response to substance ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link decreases response to substance ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link multiple interactions EXP 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases activity EXP 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases phosphorylation EXP 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link multiple interactions EXP 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases expression ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases expression ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases expression ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases expression ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases response to substance ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tyms thymidylate synthetase GBrowse link increases expression ISO 9 112,604,912 112,617,706 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link decreases expression ISO 9 10,520,730 10,536,071 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link decreases response to substance ISO 9 10,520,730 10,536,071 RGD:6480464 CTD
G Xiap X-linked inhibitor of apoptosis GBrowse link multiple interactions ISO X 3,011,520 3,047,798 RGD:6480464 CTD
G Xiap X-linked inhibitor of apoptosis GBrowse link multiple interactions ISO X 3,011,520 3,047,798 RGD:6480464 CTD
G Xiap X-linked inhibitor of apoptosis GBrowse link decreases response to substance ISO X 3,011,520 3,047,798 RGD:6480464 CTD
G Xrcc4 X-ray repair complementing defective repair in Chinese hamster cells 4 GBrowse link decreases response to substance ISO 2 19,904,490 20,158,358 RGD:6480464 CTD
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 501881
    role 491510
      biological role 489686
        biochemical role 195456
          metabolite 176736
            secondary metabolite 172069
              camptothecin 191
Path 2
Term Annotations click to browse term
  CHEBI ontology 501881
    subatomic particle 500845
      composite particle 500845
        hadron 500845
          baryon 500845
            nucleon 500845
              atomic nucleus 500845
                atom 500845
                  main group element atom 470301
                    p-block element atom 467779
                      carbon group element atom 419149
                        carbon atom 415667
                          organic molecular entity 415660
                            organic molecule 365810
                              organic cyclic compound 304492
                                organic heterocyclic compound 158510
                                  organic heteropolycyclic compound 97199
                                    organic heteropentacyclic compound 9724
                                      pyranoindolizinoquinoline 479
                                        camptothecin 191
paths to the root

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