ONTOLOGY REPORT - ANNOTATIONS
| Term: | mitomycin C |
|
| Accession: | CHEBI:27504
|
browse the term
|
| Definition: | A mitomycin that has formula C15H18N4O5. |
| Synonyms: | exact_synonym: | [(1aS,8S,8aR,8bS)-6-amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate |
| | related_synonym: | 7-Amino-9alpha-methoxymitosane; Ametycine; C15H18N4O5; InChI=1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1; InChIKey=NWIBSHFKIJFRCO-WUDYKRTCSA-N; MMC; Mitocin-C; Mitomycin; Mutamycin; [H][C@]12CN3C4=C([C@@H](COC(N)=O)[C@@]3(OC)[C@@]1([H])N2)C(=O)C(N)=C(C)C4=O |
| | alt_id: | CHEBI:25356; CHEBI:6953 |
| | xref_casrn: | 50-07-7 |
| | xref: | Beilstein:3570056 "Beilstein Registry Number"; ChEMBL:113590 "ChEMBL COMPOUND"; ChemIDplus:50-07-7 "CAS Registry Number"; DrugBank:DB00305 "DrugBank"; KEGG COMPOUND:50-07-7 "CAS Registry Number"; KEGG COMPOUND:C06681 "KEGG COMPOUND" |
| | xref_mesh: | MESH:D016685 |
| | xref: | Wikipedia:Mitomycin "Wikipedia" |
|
|
mitomycin C
|
| G |
Abcb1a |
ATP-binding cassette, sub-family B (MDR/TAP), member 1A |
|
increases expression |
ISO |
4 |
21,709,855 |
21,796,628 |
RGD:6480464 |
CTD |
| G |
Abcc1 |
ATP-binding cassette, subfamily C (CFTR/MRP), member 1 |
|
decreases response to substance |
ISO |
10 |
452,239 |
575,705 |
RGD:6480464 |
CTD |
| G |
Ablim1 |
actin-binding LIM protein 1 |
|
affects response to substance |
ISO |
1 |
263,380,818 |
263,465,905 |
RGD:6480464 |
CTD |
| G |
Aco1 |
aconitase 1, soluble |
|
affects response to substance |
ISO |
5 |
57,536,675 |
57,591,765 |
RGD:6480464 |
CTD |
| G |
Acot2 |
acyl-CoA thioesterase 2 |
|
affects response to substance |
ISO |
6 |
108,017,574 |
108,024,387 |
RGD:6480464 |
CTD |
| G |
Acsl1 |
acyl-CoA synthetase long-chain family member 1 |
|
affects response to substance |
ISO |
16 |
49,036,892 |
49,081,416 |
RGD:6480464 |
CTD |
| G |
Acsl3 |
acyl-CoA synthetase long-chain family member 3 |
|
affects response to substance |
ISO |
9 |
78,083,239 |
78,106,933 |
RGD:6480464 |
CTD |
| G |
Ahcyl1 |
adenosylhomocysteinase-like 1 |
|
affects response to substance |
ISO |
2 |
203,210,376 |
203,244,218 |
RGD:6480464 |
CTD |
| G |
Akap12 |
A kinase (PRKA) anchor protein 12 |
|
affects response to substance |
ISO |
1 |
34,979,039 |
35,068,763 |
RGD:6480464 |
CTD |
| G |
Akt1 |
v-akt murine thymoma viral oncogene homolog 1 |
|
decreases expression |
ISO |
6 |
137,640,482 |
137,657,552 |
RGD:6480464 |
CTD |
| G |
Alcam |
activated leukocyte cell adhesion molecule |
|
affects response to substance |
ISO |
11 |
49,424,243 |
49,630,071 |
RGD:6480464 |
CTD |
| G |
Aldh3a1 |
aldehyde dehydrogenase 3 family, member A1 |
|
affects response to substance |
ISO |
10 |
47,365,195 |
47,374,880 |
RGD:6480464 |
CTD |
| G |
Aox1 |
aldehyde oxidase 1 |
|
affects response to substance |
ISO |
9 |
56,693,698 |
56,774,115 |
RGD:6480464 |
CTD |
| G |
Apeh |
N-acylaminoacyl-peptide hydrolase |
|
affects response to substance |
ISO |
8 |
113,353,151 |
113,362,263 |
RGD:6480464 |
CTD |
| G |
Apex1 |
APEX nuclease (multifunctional DNA repair enzyme) 1 |
|
multiple interactions |
ISO |
15 |
26,904,124 |
26,906,224 |
RGD:6480464 |
CTD |
| G |
Apex1 |
APEX nuclease (multifunctional DNA repair enzyme) 1 |
|
multiple interactions |
ISO |
15 |
26,904,124 |
26,906,224 |
RGD:6480464 |
CTD |
| G |
App |
amyloid beta (A4) precursor protein |
|
increases expression |
ISO |
11 |
24,457,855 |
24,693,851 |
RGD:6480464 |
CTD |
| G |
Asah1 |
N-acylsphingosine amidohydrolase (acid ceramidase) 1 |
|
affects response to substance |
ISO |
16 |
54,279,253 |
54,311,084 |
RGD:6480464 |
CTD |
| G |
Atf4 |
activating transcription factor 4 (tax-responsive enhancer element B67) |
|
increases expression |
ISO |
7 |
118,537,718 |
118,538,994 |
RGD:6480464 |
CTD |
| G |
Atp1a1 |
ATPase, Na+/K+ transporting, alpha 1 polypeptide |
|
affects response to substance |
ISO |
2 |
196,657,749 |
196,687,242 |
RGD:6480464 |
CTD |
| G |
Atrx |
alpha thalassemia/mental retardation syndrome X-linked |
|
affects response to substance |
ISO |
X |
93,903,794 |
94,051,337 |
RGD:6480464 |
CTD |
| G |
Avpi1 |
arginine vasopressin-induced 1 |
|
affects response to substance |
ISO |
1 |
248,727,385 |
248,733,112 |
RGD:6480464 |
CTD |
| G |
Bace2 |
beta-site APP-cleaving enzyme 2 |
|
affects response to substance |
ISO |
11 |
37,345,568 |
37,428,155 |
RGD:6480464 |
CTD |
| G |
Bad |
BCL2-associated agonist of cell death |
|
increases expression |
ISO |
1 |
209,617,373 |
209,626,292 |
RGD:6480464 |
CTD |
| G |
Bambi |
BMP and activin membrane-bound inhibitor, homolog (Xenopus laevis) |
|
affects response to substance |
ISO |
17 |
62,654,385 |
62,658,641 |
RGD:6480464 |
CTD |
| G |
Bax |
Bcl2-associated X protein |
|
affects localization |
ISO |
1 |
95,933,023 |
95,938,176 |
RGD:6480464 |
CTD |
| G |
Bax |
Bcl2-associated X protein |
|
increases expression |
ISO |
1 |
95,933,023 |
95,938,176 |
RGD:6480464 |
CTD |
| G |
Bax |
Bcl2-associated X protein |
|
decreases expression |
ISO |
1 |
95,933,023 |
95,938,176 |
RGD:6480464 |
CTD |
| G |
Bax |
Bcl2-associated X protein |
|
multiple interactions |
ISO |
1 |
95,933,023 |
95,938,176 |
RGD:6480464 |
CTD |
| G |
Bax |
Bcl2-associated X protein |
|
increases expression |
ISO |
1 |
95,933,023 |
95,938,176 |
RGD:6480464 |
CTD |
| G |
Bax |
Bcl2-associated X protein |
|
multiple interactions |
ISO |
1 |
95,933,023 |
95,938,176 |
RGD:6480464 |
CTD |
| G |
Bax |
Bcl2-associated X protein |
|
increases expression |
ISO |
1 |
95,933,023 |
95,938,176 |
RGD:6480464 |
CTD |
| G |
Bcl2 |
B-cell CLL/lymphoma 2 |
|
affects expression |
ISO |
13 |
12,730,736 |
12,905,108 |
RGD:6480464 |
CTD |
| G |
Bcl2 |
B-cell CLL/lymphoma 2 |
|
increases expression |
ISO |
13 |
12,730,736 |
12,905,108 |
RGD:6480464 |
CTD |
| G |
Bcl2 |
B-cell CLL/lymphoma 2 |
|
increases expression |
ISO |
13 |
12,730,736 |
12,905,108 |
RGD:6480464 |
CTD |
| G |
Bcl2 |
B-cell CLL/lymphoma 2 |
|
multiple interactions |
ISO |
13 |
12,730,736 |
12,905,108 |
RGD:6480464 |
CTD |
| G |
Bcl2 |
B-cell CLL/lymphoma 2 |
|
multiple interactions |
ISO |
13 |
12,730,736 |
12,905,108 |
RGD:6480464 |
CTD |
| G |
Bcl2 |
B-cell CLL/lymphoma 2 |
|
increases expression |
ISO |
13 |
12,730,736 |
12,905,108 |
RGD:6480464 |
CTD |
| G |
Bcl2l1 |
Bcl2-like 1 |
|
decreases expression |
ISO |
3 |
143,129,087 |
143,180,199 |
RGD:6480464 |
CTD |
| G |
Bcl2l1 |
Bcl2-like 1 |
|
increases expression |
ISO |
3 |
143,129,087 |
143,180,199 |
RGD:6480464 |
CTD |
| G |
Bin3 |
bridging integrator 3 |
|
affects response to substance |
ISO |
15 |
50,519,884 |
50,539,242 |
RGD:6480464 |
CTD |
| G |
Birc2 |
baculoviral IAP repeat-containing 2 |
|
affects response to substance |
ISO |
8 |
4,649,559 |
4,667,733 |
RGD:6480464 |
CTD |
| G |
Birc5 |
baculoviral IAP repeat-containing 5 |
|
increases expression |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Bmp4 |
bone morphogenetic protein 4 |
|
decreases expression |
ISO |
15 |
22,283,171 |
22,286,757 |
RGD:6480464 |
CTD |
| G |
Bscl2 |
Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
|
increases expression |
ISO |
1 |
211,509,675 |
211,518,963 |
RGD:6480464 |
CTD |
| G |
Btg2 |
BTG family, member 2 |
|
increases expression |
ISO |
13 |
47,026,986 |
47,030,745 |
RGD:6480464 |
CTD |
| G |
Cadps2 |
Ca++-dependent secretion activator 2 |
|
affects response to substance |
ISO |
4 |
49,658,535 |
50,206,014 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
multiple interactions |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
increases activity |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
multiple interactions |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
multiple interactions |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
increases cleavage |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
increases activity |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
increases activity |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
increases activity |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
increases activity |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
increases cleavage |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
increases activity |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
increases activity |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Casp7 |
caspase 7 |
|
multiple interactions |
ISO |
1 |
262,689,300 |
262,721,591 |
RGD:6480464 |
CTD |
| G |
Casp8 |
caspase 8 |
|
increases activity |
ISO |
9 |
57,389,353 |
57,437,803 |
RGD:6480464 |
CTD |
| G |
Casp8 |
caspase 8 |
|
multiple interactions |
ISO |
9 |
57,389,353 |
57,437,803 |
RGD:6480464 |
CTD |
| G |
Casp8 |
caspase 8 |
|
increases cleavage |
ISO |
9 |
57,389,353 |
57,437,803 |
RGD:6480464 |
CTD |
| G |
Casp8 |
caspase 8 |
|
increases activity |
ISO |
9 |
57,389,353 |
57,437,803 |
RGD:6480464 |
CTD |
| G |
Casp8 |
caspase 8 |
|
increases cleavage |
ISO |
9 |
57,389,353 |
57,437,803 |
RGD:6480464 |
CTD |
| G |
Casp8 |
caspase 8 |
|
increases activity |
ISO |
9 |
57,389,353 |
57,437,803 |
RGD:6480464 |
CTD |
| G |
Casp8 |
caspase 8 |
|
increases activity |
ISO |
9 |
57,389,353 |
57,437,803 |
RGD:6480464 |
CTD |
| G |
Casp9 |
caspase 9, apoptosis-related cysteine peptidase |
|
multiple interactions |
ISO |
5 |
160,704,234 |
160,721,796 |
RGD:6480464 |
CTD |
| G |
Casp9 |
caspase 9, apoptosis-related cysteine peptidase |
|
increases activity |
ISO |
5 |
160,704,234 |
160,721,796 |
RGD:6480464 |
CTD |
| G |
Casp9 |
caspase 9, apoptosis-related cysteine peptidase |
|
multiple interactions |
ISO |
5 |
160,704,234 |
160,721,796 |
RGD:6480464 |
CTD |
| G |
Casp9 |
caspase 9, apoptosis-related cysteine peptidase |
|
increases activity |
ISO |
5 |
160,704,234 |
160,721,796 |
RGD:6480464 |
CTD |
| G |
Casp9 |
caspase 9, apoptosis-related cysteine peptidase |
|
increases activity |
ISO |
5 |
160,704,234 |
160,721,796 |
RGD:6480464 |
CTD |
| G |
Casp9 |
caspase 9, apoptosis-related cysteine peptidase |
|
increases activity |
ISO |
5 |
160,704,234 |
160,721,796 |
RGD:6480464 |
CTD |
| G |
Ccl2 |
chemokine (C-C motif) ligand 2 |
|
multiple interactions |
ISO |
10 |
70,256,263 |
70,258,061 |
RGD:6480464 |
CTD |
| G |
Ccl2 |
chemokine (C-C motif) ligand 2 |
|
increases expression |
ISO |
10 |
70,256,263 |
70,258,061 |
RGD:6480464 |
CTD |
| G |
Ccl2 |
chemokine (C-C motif) ligand 2 |
|
increases secretion |
ISO |
10 |
70,256,263 |
70,258,061 |
RGD:6480464 |
CTD |
| G |
Ccnb1 |
cyclin B1 |
|
multiple interactions |
ISO |
2 |
31,574,600 |
31,581,784 |
RGD:6480464 |
CTD |
| G |
Ccnb1 |
cyclin B1 |
|
increases expression |
ISO |
2 |
31,574,600 |
31,581,784 |
RGD:6480464 |
CTD |
| G |
Ccnb1 |
cyclin B1 |
|
increases expression |
ISO |
2 |
31,574,600 |
31,581,784 |
RGD:6480464 |
CTD |
| G |
Cd59 |
CD59 molecule, complement regulatory protein |
|
increases mutagenesis |
ISO |
3 |
89,243,600 |
89,245,129 |
RGD:6480464 |
CTD |
| G |
Cd9 |
CD9 molecule |
|
affects response to substance |
ISO |
4 |
162,279,462 |
162,312,889 |
RGD:6480464 |
CTD |
| G |
Cda |
cytidine deaminase |
|
multiple interactions |
ISO |
5 |
157,117,303 |
157,143,989 |
RGD:6480464 |
CTD |
| G |
Cdk2 |
cyclin dependent kinase 2 |
|
affects response to substance |
ISO |
7 |
2,000,196 |
2,007,682 |
RGD:6480464 |
CTD |
| G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
|
multiple interactions |
ISO |
20 |
7,376,325 |
7,386,778 |
RGD:6480464 |
CTD |
| G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
|
multiple interactions |
ISO |
20 |
7,376,325 |
7,386,778 |
RGD:6480464 |
CTD |
| G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
|
increases expression |
ISO |
20 |
7,376,325 |
7,386,778 |
RGD:6480464 |
CTD |
| G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
|
multiple interactions |
ISO |
20 |
7,376,325 |
7,386,778 |
RGD:6480464 |
CTD |
| G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
|
affects response to substance |
ISO |
4 |
171,841,705 |
171,846,506 |
RGD:6480464 |
CTD |
| G |
Cep57 |
centrosomal protein 57 |
|
affects response to substance |
ISO |
8 |
10,608,688 |
10,627,914 |
RGD:6480464 |
CTD |
| G |
Chic2 |
cysteine-rich hydrophobic domain 2 |
|
affects response to substance |
ISO |
14 |
35,522,470 |
35,558,067 |
RGD:6480464 |
CTD |
| G |
Ckmt1b |
creatine kinase, mitochondrial 1B |
|
affects response to substance |
ISO |
3 |
108,158,887 |
108,163,888 |
RGD:6480464 |
CTD |
| G |
Clgn |
calmegin |
|
affects response to substance |
ISO |
19 |
26,404,126 |
26,436,081 |
RGD:6480464 |
CTD |
| G |
Coch |
coagulation factor C homolog, cochlin (Limulus polyphemus) |
|
affects response to substance |
ISO |
6 |
71,692,946 |
71,697,056 |
RGD:6480464 |
CTD |
| G |
Col4a2 |
collagen, type IV, alpha 2 |
|
affects response to substance |
ISO |
16 |
82,899,206 |
83,045,102 |
RGD:6480464 |
CTD |
| G |
Col9a3 |
collagen, type IX, alpha 3 |
|
affects response to substance |
ISO |
3 |
169,704,893 |
169,712,492 |
RGD:6480464 |
CTD |
| G |
Cox17 |
cytochrome c oxidase assembly homolog 17 (yeast) |
|
affects response to substance |
ISO |
11 |
64,183,573 |
64,185,985 |
RGD:6480464 |
CTD |
| G |
Cps1 |
carbamoyl-phosphate synthetase 1 |
|
affects response to substance |
ISO |
9 |
65,907,211 |
66,017,942 |
RGD:6480464 |
CTD |
| G |
Ctdspl |
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
|
affects response to substance |
ISO |
8 |
123,960,578 |
123,993,452 |
RGD:6480464 |
CTD |
| G |
Ctnna1 |
catenin (cadherin-associated protein), alpha 1, 102kDa |
|
affects response to substance |
ISO |
18 |
27,629,915 |
27,769,360 |
RGD:6480464 |
CTD |
| G |
Cxcl5 |
chemokine (C-X-C motif) ligand 5 |
|
affects response to substance |
ISO |
14 |
18,825,357 |
18,826,269 |
RGD:6480464 |
CTD |
| G |
Cycs |
cytochrome c, somatic |
|
multiple interactions |
ISO |
4 |
78,825,878 |
78,827,978 |
RGD:6480464 |
CTD |
| G |
Cycs |
cytochrome c, somatic |
|
increases secretion |
ISO |
4 |
78,825,878 |
78,827,978 |
RGD:6480464 |
CTD |
| G |
Cycs |
cytochrome c, somatic |
|
increases secretion |
ISO |
4 |
78,825,878 |
78,827,978 |
RGD:6480464 |
CTD |
| G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
|
decreases activity |
EXP |
8 |
61,439,062 |
61,447,861 |
RGD:6480464 |
CTD |
| G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
|
multiple interactions |
ISO |
1 |
81,266,828 |
81,290,471 |
RGD:6480464 |
CTD |
| G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
|
multiple interactions |
EXP |
1 |
81,266,828 |
81,290,471 |
RGD:6480464 |
CTD |
| G |
Cyp2c11 |
cytochrome P450, subfamily 2, polypeptide 11 |
|
decreases activity |
EXP |
1 |
243,281,320 |
243,320,945 |
RGD:6480464 |
CTD |
| G |
Cyp2d1 |
cytochrome P450, family 2, subfamily d, polypeptide 1 |
|
decreases activity |
EXP |
7 |
120,769,701 |
120,774,105 |
RGD:6480464 |
CTD |
| G |
Cyp2d2 |
cytochrome P450, family 2, subfamily d, polypeptide 2 |
|
decreases activity |
EXP |
7 |
120,796,210 |
120,800,279 |
RGD:6480464 |
CTD |
| G |
Dclre1c |
DNA cross-link repair 1C |
|
decreases response to substance |
ISO |
17 |
85,896,581 |
85,928,644 |
RGD:6480464 |
CTD |
| G |
Dct |
dopachrome tautomerase |
|
affects response to substance |
ISO |
15 |
102,798,699 |
102,832,240 |
RGD:6480464 |
CTD |
| G |
Ddb2 |
damage specific DNA binding protein 2 |
|
multiple interactions |
ISO |
3 |
75,568,487 |
75,591,428 |
RGD:6480464 |
CTD |
| G |
Ddb2 |
damage specific DNA binding protein 2 |
|
increases expression |
ISO |
3 |
75,568,487 |
75,591,428 |
RGD:6480464 |
CTD |
| G |
Ddit4 |
DNA-damage-inducible transcript 4 |
|
affects response to substance |
ISO |
20 |
27,252,273 |
27,254,371 |
RGD:6480464 |
CTD |
| G |
Ddr1 |
discoidin domain receptor tyrosine kinase 1 |
|
affects response to substance |
ISO |
20 |
3,194,265 |
3,214,611 |
RGD:6480464 |
CTD |
| G |
Dkk3 |
dickkopf 3 homolog (Xenopus laevis) |
|
affects response to substance |
ISO |
1 |
169,924,617 |
169,964,692 |
RGD:6480464 |
CTD |
| G |
Dmd |
dystrophin |
|
affects response to substance |
ISO |
X |
71,501,362 |
71,671,414 |
RGD:6480464 |
CTD |
| G |
Drap1 |
Dr1 associated protein 1 (negative cofactor 2 alpha) |
|
affects response to substance |
ISO |
1 |
208,067,906 |
208,070,556 |
RGD:6480464 |
CTD |
| G |
Dse |
dermatan sulfate epimerase |
|
affects response to substance |
ISO |
20 |
37,568,889 |
37,647,574 |
RGD:6480464 |
CTD |
| G |
Dusp4 |
dual specificity phosphatase 4 |
|
affects response to substance |
ISO |
16 |
61,109,626 |
61,119,981 |
RGD:6480464 |
CTD |
| G |
Egf |
epidermal growth factor |
|
multiple interactions |
ISO |
2 |
227,103,900 |
227,195,062 |
RGD:6480464 |
CTD |
| G |
Egr1 |
early growth response 1 |
|
affects response to substance |
ISO |
18 |
27,343,919 |
27,346,117 |
RGD:6480464 |
CTD |
| G |
Egr1 |
early growth response 1 |
|
increases expression |
ISO |
18 |
27,343,919 |
27,346,117 |
RGD:6480464 |
CTD |
| G |
Eif5b |
eukaryotic translation initiation factor 5B |
|
affects response to substance |
ISO |
9 |
36,937,415 |
36,993,650 |
RGD:6480464 |
CTD |
| G |
Eif5b-ps1 |
eukaryotic translation initiation factor 5B, pseudogene 1 |
|
affects response to substance |
ISO |
19 |
37,343,402 |
37,347,524 |
RGD:6480464 |
CTD |
| G |
Elk3 |
ELK3, member of ETS oncogene family |
|
affects response to substance |
ISO |
7 |
30,278,949 |
30,314,430 |
RGD:6480464 |
CTD |
| G |
Emp2 |
epithelial membrane protein 2 |
|
affects response to substance |
ISO |
10 |
5,311,157 |
5,348,038 |
RGD:6480464 |
CTD |
| G |
Epha2 |
Eph receptor A2 |
|
decreases expression |
ISO |
5 |
160,185,143 |
160,214,727 |
RGD:6480464 |
CTD |
| G |
Ephx1 |
epoxide hydrolase 1, microsomal (xenobiotic) |
|
increases expression |
ISO |
13 |
96,722,973 |
96,752,940 |
RGD:6480464 |
CTD |
| G |
Erbb3 |
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) |
|
affects response to substance |
ISO |
7 |
1,858,057 |
1,877,353 |
RGD:6480464 |
CTD |
| G |
Ervfrd-1 |
endogenous retrovirus group FRD, member 1 |
|
affects response to substance |
ISO |
15 |
49,853,767 |
49,855,636 |
RGD:6480464 |
CTD |
| G |
F2r |
coagulation factor II (thrombin) receptor |
|
affects response to substance |
ISO |
2 |
25,985,800 |
25,989,072 |
RGD:6480464 |
CTD |
| G |
Fam171a1 |
family with sequence similarity 171, member A1 |
|
affects response to substance |
ISO |
17 |
86,143,621 |
86,266,740 |
RGD:6480464 |
CTD |
| G |
Fam46a |
family with sequence similarity 46, member A |
|
affects response to substance |
ISO |
8 |
90,502,441 |
90,506,129 |
RGD:6480464 |
CTD |
| G |
Fan1 |
FANCD2/FANCI-associated nuclease 1 |
|
decreases response to substance |
ISO |
1 |
118,784,938 |
118,811,928 |
RGD:6480464 |
CTD |
| G |
Fan1 |
FANCD2/FANCI-associated nuclease 1 |
|
increases response to substance |
ISO |
1 |
118,784,938 |
118,811,928 |
RGD:6480464 |
CTD |
| G |
Fas |
Fas (TNF receptor superfamily, member 6) |
|
affects splicing |
ISO |
1 |
238,259,443 |
238,274,745 |
RGD:6480464 |
CTD |
| G |
Fas |
Fas (TNF receptor superfamily, member 6) |
|
increases expression |
ISO |
1 |
238,259,443 |
238,274,745 |
RGD:6480464 |
CTD |
| G |
Fas |
Fas (TNF receptor superfamily, member 6) |
|
increases expression |
ISO |
1 |
238,259,443 |
238,274,745 |
RGD:6480464 |
CTD |
| G |
Fas |
Fas (TNF receptor superfamily, member 6) |
|
multiple interactions |
ISO |
1 |
238,259,443 |
238,274,745 |
RGD:6480464 |
CTD |
| G |
Fas |
Fas (TNF receptor superfamily, member 6) |
|
increases expression |
ISO |
1 |
238,259,443 |
238,274,745 |
RGD:6480464 |
CTD |
| G |
Fas |
Fas (TNF receptor superfamily, member 6) |
|
increases expression |
ISO |
1 |
238,259,443 |
238,274,745 |
RGD:6480464 |
CTD |
| G |
Fas |
Fas (TNF receptor superfamily, member 6) |
|
increases expression |
ISO |
1 |
238,259,443 |
238,274,745 |
RGD:6480464 |
CTD |
| G |
Faslg |
Fas ligand (TNF superfamily, member 6) |
|
increases expression |
ISO |
13 |
77,472,950 |
77,480,210 |
RGD:6480464 |
CTD |
| G |
Faslg |
Fas ligand (TNF superfamily, member 6) |
|
increases expression |
ISO |
13 |
77,472,950 |
77,480,210 |
RGD:6480464 |
CTD |
| G |
Faslg |
Fas ligand (TNF superfamily, member 6) |
|
increases expression |
ISO |
13 |
77,472,950 |
77,480,210 |
RGD:6480464 |
CTD |
| G |
Faslg |
Fas ligand (TNF superfamily, member 6) |
|
increases expression |
ISO |
13 |
77,472,950 |
77,480,210 |
RGD:6480464 |
CTD |
| G |
Fat1 |
FAT tumor suppressor homolog 1 (Drosophila) |
|
affects response to substance |
ISO |
16 |
50,472,074 |
50,591,399 |
RGD:6480464 |
CTD |
| G |
Fbl |
fibrillarin |
|
affects localization |
ISO |
1 |
83,271,967 |
83,281,069 |
RGD:6480464 |
CTD |
| G |
Fdft1 |
farnesyl diphosphate farnesyl transferase 1 |
|
affects response to substance |
ISO |
15 |
42,425,336 |
42,453,390 |
RGD:6480464 |
CTD |
| G |
Fgf2 |
fibroblast growth factor 2 |
|
increases expression |
ISO |
2 |
123,893,314 |
123,947,136 |
RGD:6480464 |
CTD |
| G |
Fhl1 |
four and a half LIM domains 1 |
|
affects response to substance |
ISO |
X |
141,315,765 |
141,329,278 |
RGD:6480464 |
CTD |
| G |
Fis1 |
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) |
|
affects response to substance |
ISO |
12 |
20,806,840 |
20,821,766 |
RGD:6480464 |
CTD |
| G |
Fos |
FBJ osteosarcoma oncogene |
|
affects response to substance |
ISO |
6 |
109,559,135 |
109,562,001 |
RGD:6480464 |
CTD |
| G |
Fyn |
FYN oncogene related to SRC, FGR, YES |
|
affects response to substance |
ISO |
20 |
43,501,853 |
43,695,567 |
RGD:6480464 |
CTD |
| G |
G0s2 |
G0/G1switch 2 |
|
affects response to substance |
ISO |
13 |
109,121,297 |
109,122,209 |
RGD:6480464 |
CTD |
| G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
|
multiple interactions |
ISO |
4 |
96,649,941 |
96,652,243 |
RGD:6480464 |
CTD |
| G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
|
increases expression |
ISO |
4 |
96,649,941 |
96,652,243 |
RGD:6480464 |
CTD |
| G |
Gpr56 |
G protein-coupled receptor 56 |
|
affects response to substance |
ISO |
19 |
10,438,332 |
10,475,607 |
RGD:6480464 |
CTD |
| G |
Gpsm2 |
G-protein signaling modulator 2 |
|
affects response to substance |
ISO |
2 |
204,278,765 |
204,319,522 |
RGD:6480464 |
CTD |
| G |
Gstm4 |
glutathione S-transferase mu 4 |
|
affects response to substance |
ISO |
2 |
203,605,593 |
203,610,817 |
RGD:6480464 |
CTD |
| G |
Gstp1 |
glutathione S-transferase pi 1 |
|
increases response to substance |
ISO |
1 |
206,627,398 |
206,629,866 |
RGD:6480464 |
CTD |
| G |
Gstp1 |
glutathione S-transferase pi 1 |
|
decreases response to substance |
EXP |
1 |
206,627,398 |
206,629,866 |
RGD:6480464 |
CTD |
| G |
H2afx |
H2A histone family, member X |
|
increases phosphorylation |
ISO |
8 |
47,312,609 |
47,313,938 |
RGD:6480464 |
CTD |
| G |
Hcls1 |
hematopoietic cell specific Lyn substrate 1 |
|
affects response to substance |
ISO |
11 |
65,619,701 |
65,643,533 |
RGD:6480464 |
CTD |
| G |
Hdac9 |
histone deacetylase 9 |
|
affects response to substance |
ISO |
6 |
53,066,308 |
53,114,402 |
RGD:6480464 |
CTD |
| G |
Hey1 |
hairy/enhancer-of-split related with YRPW motif 1 |
|
affects response to substance |
ISO |
2 |
95,174,030 |
95,176,430 |
RGD:6480464 |
CTD |
| G |
Hhex |
hematopoietically expressed homeobox |
|
affects response to substance |
ISO |
1 |
241,736,542 |
241,742,129 |
RGD:6480464 |
CTD |
| G |
Hmg20b |
high mobility group 20 B |
|
affects response to substance |
ISO |
7 |
9,853,290 |
9,857,970 |
RGD:6480464 |
CTD |
| G |
Hmga1 |
high mobility group AT-hook 1 |
|
affects response to substance |
ISO |
20 |
5,769,052 |
5,772,269 |
RGD:6480464 |
CTD |
| G |
Hmga2 |
high mobility group AT-hook 2 |
|
affects response to substance |
ISO |
7 |
59,638,555 |
59,753,791 |
RGD:6480464 |
CTD |
| G |
Hspa8 |
heat shock 70kDa protein 8 |
|
multiple interactions |
ISO |
8 |
43,784,035 |
43,787,760 |
RGD:6480464 |
CTD |
| G |
Hspa8 |
heat shock 70kDa protein 8 |
|
increases expression |
ISO |
8 |
43,784,035 |
43,787,760 |
RGD:6480464 |
CTD |
| G |
Icmt |
isoprenylcysteine carboxyl methyltransferase |
|
affects response to substance |
ISO |
5 |
169,526,961 |
169,533,722 |
RGD:6480464 |
CTD |
| G |
Id4 |
inhibitor of DNA binding 4 |
|
affects response to substance |
ISO |
17 |
22,525,292 |
22,527,861 |
RGD:6480464 |
CTD |
| G |
Il18 |
interleukin 18 |
|
decreases expression |
ISO |
8 |
53,936,584 |
53,943,228 |
RGD:6480464 |
CTD |
| G |
Il18 |
interleukin 18 |
|
decreases expression |
ISO |
8 |
53,936,584 |
53,943,228 |
RGD:6480464 |
CTD |
| G |
Il1b |
interleukin 1 beta |
|
multiple interactions |
ISO |
3 |
116,964,422 |
116,970,867 |
RGD:6480464 |
CTD |
| G |
Il1b |
interleukin 1 beta |
|
affects response to substance |
ISO |
3 |
116,964,422 |
116,970,867 |
RGD:6480464 |
CTD |
| G |
Impa2 |
inositol (myo)-1(or 4)-monophosphatase 2 |
|
affects response to substance |
ISO |
18 |
63,809,336 |
63,840,069 |
RGD:6480464 |
CTD |
| G |
Jmjd1c |
jumonji domain containing 1C |
|
affects response to substance |
ISO |
20 |
22,151,774 |
22,283,264 |
RGD:6480464 |
CTD |
| G |
Kank1 |
KN motif and ankyrin repeat domains 1 |
|
affects response to substance |
ISO |
1 |
228,748,121 |
228,868,261 |
RGD:6480464 |
CTD |
| G |
Kazn |
kazrin, periplakin interacting protein |
|
affects response to substance |
ISO |
5 |
161,041,203 |
161,399,651 |
RGD:6480464 |
CTD |
| G |
Kif23 |
kinesin family member 23 |
|
affects response to substance |
ISO |
8 |
66,050,163 |
66,077,265 |
RGD:6480464 |
CTD |
| G |
L1cam |
L1 cell adhesion molecule |
|
affects response to substance |
ISO |
X |
159,784,792 |
159,801,553 |
RGD:6480464 |
CTD |
| G |
Lgals3 |
lectin, galactoside-binding, soluble, 3 |
|
affects response to substance |
ISO |
15 |
23,327,071 |
23,339,006 |
RGD:6480464 |
CTD |
| G |
Lig1 |
ligase I, DNA, ATP-dependent |
|
decreases expression |
ISO |
1 |
73,728,892 |
73,767,429 |
RGD:6480464 |
CTD |
| G |
Limch1 |
LIM and calponin homology domains 1 |
|
affects response to substance |
ISO |
14 |
43,722,254 |
44,049,555 |
RGD:6480464 |
CTD |
| G |
Litaf |
lipopolysaccharide-induced TNF factor |
|
affects response to substance |
ISO |
10 |
4,614,177 |
4,623,903 |
RGD:6480464 |
CTD |
| G |
Lmna |
lamin A/C |
|
affects response to substance |
ISO |
2 |
180,595,724 |
180,616,354 |
RGD:6480464 |
CTD |
| G |
Ltbp2 |
latent transforming growth factor beta binding protein 2 |
|
affects response to substance |
ISO |
6 |
108,826,446 |
108,924,746 |
RGD:6480464 |
CTD |
| G |
Magoh |
mago-nashi homolog, proliferation-associated (Drosophila) |
|
affects response to substance |
ISO |
5 |
128,982,276 |
128,989,724 |
RGD:6480464 |
CTD |
| G |
Map2k1 |
mitogen activated protein kinase kinase 1 |
|
multiple interactions |
ISO |
8 |
68,379,074 |
68,451,554 |
RGD:6480464 |
CTD |
| G |
Map2k2 |
mitogen activated protein kinase kinase 2 |
|
multiple interactions |
ISO |
7 |
10,074,654 |
10,094,003 |
RGD:6480464 |
CTD |
| G |
Map7 |
microtubule-associated protein 7 |
|
affects response to substance |
ISO |
1 |
15,440,422 |
15,553,260 |
RGD:6480464 |
CTD |
| G |
Mapk1 |
mitogen activated protein kinase 1 |
|
multiple interactions |
ISO |
11 |
85,968,732 |
86,030,387 |
RGD:6480464 |
CTD |
| G |
Mapk1 |
mitogen activated protein kinase 1 |
|
increases phosphorylation |
ISO |
11 |
85,968,732 |
86,030,387 |
RGD:6480464 |
CTD |
| G |
Mapk14 |
mitogen activated protein kinase 14 |
|
multiple interactions |
ISO |
20 |
6,939,249 |
7,000,378 |
RGD:6480464 |
CTD |
| G |
Mapk3 |
mitogen activated protein kinase 3 |
|
multiple interactions |
ISO |
1 |
185,935,044 |
185,941,245 |
RGD:6480464 |
CTD |
| G |
Mapk3 |
mitogen activated protein kinase 3 |
|
increases phosphorylation |
ISO |
1 |
185,935,044 |
185,941,245 |
RGD:6480464 |
CTD |
| G |
Mapk8 |
mitogen-activated protein kinase 8 |
|
multiple interactions |
ISO |
16 |
8,925,133 |
9,004,897 |
RGD:6480464 |
CTD |
| G |
Mapre1 |
microtubule-associated protein, RP/EB family, member 1 |
|
increases expression |
ISO |
3 |
144,120,532 |
144,148,856 |
RGD:6480464 |
CTD |
| G |
Matn2 |
matrilin 2 |
|
affects response to substance |
ISO |
7 |
69,715,611 |
69,880,723 |
RGD:6480464 |
CTD |
| G |
Mbp |
myelin basic protein |
|
affects response to substance |
ISO |
18 |
78,943,608 |
79,057,329 |
RGD:6480464 |
CTD |
| G |
Mdk |
midkine |
|
affects response to substance |
ISO |
3 |
76,309,988 |
76,311,345 |
RGD:6480464 |
CTD |
| G |
Mdm2 |
p53 E3 ubiquitin protein ligase |
|
multiple interactions |
ISO |
7 |
56,996,694 |
57,020,926 |
RGD:6480464 |
CTD |
| G |
Mdm2 |
p53 E3 ubiquitin protein ligase |
|
increases expression |
ISO |
7 |
56,996,694 |
57,020,926 |
RGD:6480464 |
CTD |
| G |
Mgmt |
O-6-methylguanine-DNA methyltransferase |
|
multiple interactions |
ISO |
1 |
196,629,366 |
196,866,937 |
RGD:6480464 |
CTD |
| G |
Mgmt |
O-6-methylguanine-DNA methyltransferase |
|
increases response to substance |
ISO |
1 |
196,629,366 |
196,866,937 |
RGD:6480464 |
CTD |
| G |
Mme |
membrane metallo-endopeptidase |
|
affects response to substance |
ISO |
2 |
153,031,724 |
153,114,515 |
RGD:6480464 |
CTD |
| G |
Mmp14 |
matrix metallopeptidase 14 (membrane-inserted) |
|
decreases expression |
ISO |
15 |
32,493,852 |
32,503,077 |
RGD:6480464 |
CTD |
| G |
Mok |
MOK protein kinase |
|
affects response to substance |
ISO |
6 |
135,531,656 |
135,562,497 |
RGD:6480464 |
CTD |
| G |
Mylip |
myosin regulatory light chain interacting protein |
|
affects response to substance |
ISO |
17 |
25,308,147 |
25,329,887 |
RGD:6480464 |
CTD |
| G |
Myo10 |
myosin X |
|
affects response to substance |
ISO |
2 |
77,183,028 |
77,385,896 |
RGD:6480464 |
CTD |
| G |
Nedd9 |
neural precursor cell expressed, developmentally down-regulated 9 |
|
affects response to substance |
ISO |
17 |
29,304,750 |
29,354,613 |
RGD:6480464 |
CTD |
| G |
Nfya |
nuclear transcription factor-Y alpha |
|
increases expression |
ISO |
9 |
7,970,040 |
7,994,375 |
RGD:6480464 |
CTD |
| G |
Nfya |
nuclear transcription factor-Y alpha |
|
affects response to substance |
ISO |
9 |
7,970,040 |
7,994,375 |
RGD:6480464 |
CTD |
| G |
Nmt2 |
N-myristoyltransferase 2 |
|
affects response to substance |
ISO |
17 |
86,039,838 |
86,080,243 |
RGD:6480464 |
CTD |
| G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
|
multiple interactions |
ISO |
19 |
37,251,147 |
37,266,040 |
RGD:6480464 |
CTD |
| G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
|
multiple interactions |
ISO |
19 |
37,251,147 |
37,266,040 |
RGD:6480464 |
CTD |
| G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
|
increases response to substance |
ISO |
19 |
37,251,147 |
37,266,040 |
RGD:6480464 |
CTD |
| G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
|
affects response to substance |
ISO |
19 |
37,251,147 |
37,266,040 |
RGD:6480464 |
CTD |
| G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
|
increases metabolic processing |
ISO |
19 |
37,251,147 |
37,266,040 |
RGD:6480464 |
CTD |
| G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
|
multiple interactions |
ISO |
19 |
37,251,147 |
37,266,040 |
RGD:6480464 |
CTD |
| G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
|
multiple interactions |
ISO |
19 |
37,251,147 |
37,266,040 |
RGD:6480464 |
CTD |
| G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
|
increases metabolic processing |
EXP |
19 |
37,251,147 |
37,266,040 |
RGD:6480464 |
CTD |
| G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
|
increases response to substance |
ISO |
19 |
37,251,147 |
37,266,040 |
RGD:6480464 |
CTD |
| G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
|
multiple interactions |
ISO |
19 |
37,251,147 |
37,266,040 |
RGD:6480464 |
CTD |
| G |
Nrip1 |
nuclear receptor interacting protein 1 |
|
affects response to substance |
ISO |
11 |
15,066,443 |
15,150,137 |
RGD:6480464 |
CTD |
| G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
|
multiple interactions |
ISO |
13 |
96,309,670 |
96,341,486 |
RGD:6480464 |
CTD |
| G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
|
increases activity |
ISO |
13 |
96,309,670 |
96,341,486 |
RGD:6480464 |
CTD |
| G |
Pbk |
PDZ binding kinase |
|
affects response to substance |
ISO |
15 |
45,227,251 |
45,238,096 |
RGD:6480464 |
CTD |
| G |
Pcna |
proliferating cell nuclear antigen |
|
multiple interactions |
ISO |
3 |
120,008,715 |
120,012,589 |
RGD:6480464 |
CTD |
| G |
Pcna |
proliferating cell nuclear antigen |
|
increases expression |
ISO |
3 |
120,008,715 |
120,012,589 |
RGD:6480464 |
CTD |
| G |
Pds5a |
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae) |
|
affects response to substance |
ISO |
14 |
45,242,856 |
45,339,943 |
RGD:6480464 |
CTD |
| G |
Pdxk |
pyridoxal (pyridoxine, vitamin B6) kinase |
|
affects response to substance |
ISO |
20 |
10,541,656 |
10,563,199 |
RGD:6480464 |
CTD |
| G |
Perp |
PERP, TP53 apoptosis effector |
|
increases expression |
ISO |
1 |
13,976,356 |
13,988,803 |
RGD:6480464 |
CTD |
| G |
Pir |
pirin (iron-binding nuclear protein) |
|
affects response to substance |
ISO |
X |
50,864,981 |
50,974,861 |
RGD:6480464 |
CTD |
| G |
Pkia |
protein kinase (cAMP-dependent, catalytic) inhibitor alpha |
|
affects response to substance |
ISO |
2 |
96,524,399 |
96,548,144 |
RGD:6480464 |
CTD |
| G |
Plau |
plasminogen activator, urokinase |
|
affects response to substance |
ISO |
15 |
3,680,072 |
3,686,232 |
RGD:6480464 |
CTD |
| G |
Plp1 |
proteolipid protein 1 |
|
affects response to substance |
ISO |
X |
124,488,627 |
124,503,639 |
RGD:6480464 |
CTD |
| G |
Pmel |
premelanosome protein |
|
affects response to substance |
ISO |
7 |
2,007,882 |
2,018,998 |
RGD:6480464 |
CTD |
| G |
Pmp22 |
peripheral myelin protein 22 |
|
affects response to substance |
ISO |
10 |
49,305,835 |
49,335,864 |
RGD:6480464 |
CTD |
| G |
Polb |
polymerase (DNA directed), beta |
|
decreases response to substance |
ISO |
16 |
73,864,702 |
73,888,011 |
RGD:6480464 |
CTD |
| G |
Polq |
polymerase (DNA directed), theta |
|
decreases response to substance |
ISO |
11 |
65,474,661 |
65,577,382 |
RGD:6480464 |
CTD |
| G |
Por |
P450 (cytochrome) oxidoreductase |
|
increases response to substance |
ISO |
12 |
22,078,629 |
22,097,301 |
RGD:6480464 |
CTD |
| G |
Por |
P450 (cytochrome) oxidoreductase |
|
increases response to substance |
ISO |
12 |
22,078,629 |
22,097,301 |
RGD:6480464 |
CTD |
| G |
Prkcd |
protein kinase C, delta |
|
multiple interactions |
ISO |
16 |
5,954,218 |
5,975,743 |
RGD:6480464 |
CTD |
| G |
Prkcz |
protein kinase C, zeta |
|
increases cleavage |
ISO |
5 |
172,061,825 |
172,172,793 |
RGD:6480464 |
CTD |
| G |
Prnp |
prion protein |
|
increases expression |
ISO |
3 |
119,676,137 |
119,691,507 |
RGD:6480464 |
CTD |
| G |
Prrc2c |
proline-rich coiled-coil 2C |
|
affects response to substance |
ISO |
13 |
78,332,572 |
78,400,635 |
RGD:6480464 |
CTD |
| G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
|
increases expression |
ISO |
13 |
64,427,288 |
64,432,978 |
RGD:6480464 |
CTD |
| G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
|
multiple interactions |
ISO |
13 |
64,427,288 |
64,432,978 |
RGD:6480464 |
CTD |
| G |
Rab17 |
RAB17, member RAS oncogene family |
|
affects response to substance |
ISO |
9 |
90,159,592 |
90,198,282 |
RGD:6480464 |
CTD |
| G |
Rab20 |
RAB20, member RAS oncogene family |
|
affects response to substance |
ISO |
16 |
82,871,002 |
82,895,146 |
RGD:6480464 |
CTD |
| G |
Rad51 |
RAD51 homolog (S. cerevisiae) |
|
multiple interactions |
ISO |
3 |
105,625,265 |
105,650,392 |
RGD:6480464 |
CTD |
| G |
Rad51 |
RAD51 homolog (S. cerevisiae) |
|
increases expression |
ISO |
3 |
105,625,265 |
105,650,392 |
RGD:6480464 |
CTD |
| G |
Rad51c |
Rad51 homolog c (S. cerevisiae) |
|
increases response to substance |
ISO |
10 |
75,692,205 |
75,718,369 |
RGD:6480464 |
CTD |
| G |
Rad51c |
Rad51 homolog c (S. cerevisiae) |
|
decreases response to substance |
ISO |
10 |
75,692,205 |
75,718,369 |
RGD:6480464 |
CTD |
| G |
Rassf1 |
Ras association (RalGDS/AF-6) domain family member 1 |
|
increases response to substance |
ISO |
8 |
112,798,863 |
112,810,004 |
RGD:6480464 |
CTD |
| G |
Rb1 |
retinoblastoma 1 |
|
decreases expression |
ISO |
15 |
53,828,881 |
53,962,099 |
RGD:6480464 |
CTD |
| G |
Rbbp7 |
retinoblastoma binding protein 7 |
|
increases expression |
ISO |
X |
52,669,703 |
52,688,332 |
RGD:6480464 |
CTD |
| G |
Rela |
v-rel reticuloendotheliosis viral oncogene homolog A (avian) |
|
increases expression |
ISO |
1 |
208,262,669 |
208,273,148 |
RGD:6480464 |
CTD |
| G |
Rela |
v-rel reticuloendotheliosis viral oncogene homolog A (avian) |
|
increases expression |
ISO |
1 |
208,262,669 |
208,273,148 |
RGD:6480464 |
CTD |
| G |
Rfc3 |
replication factor C (activator 1) 3 |
|
affects response to substance |
ISO |
12 |
3,224,493 |
3,235,256 |
RGD:6480464 |
CTD |
| G |
Rfc4 |
replication factor C (activator 1) 4 |
|
decreases expression |
ISO |
11 |
79,935,273 |
79,950,589 |
RGD:6480464 |
CTD |
| G |
Rps3a |
ribosomal protein S3a |
|
increases expression |
ISO |
2 |
178,092,351 |
178,096,720 |
RGD:6480464 |
CTD |
| G |
RT1-CE7 |
RT1 class I, locus CE7 |
|
decreases expression |
ISO |
20 |
3,410,094 |
3,413,041 |
RGD:6480464 |
CTD |
| G |
Runx3 |
runt-related transcription factor 3 |
|
increases response to substance |
ISO |
5 |
153,950,116 |
153,973,141 |
RGD:6480464 |
CTD |
| G |
S100a10 |
S100 calcium binding protein A10 |
|
affects response to substance |
ISO |
2 |
186,645,674 |
186,654,321 |
RGD:6480464 |
CTD |
| G |
S100a11 |
S100 calcium binding protein A11 |
|
affects response to substance |
ISO |
2 |
186,620,360 |
186,621,911 |
RGD:6480464 |
CTD |
| G |
S100a4 |
S100 calcium-binding protein A4 |
|
affects response to substance |
ISO |
2 |
182,885,070 |
182,887,380 |
RGD:6480464 |
CTD |
| G |
Sat1 |
spermidine/spermine N1-acetyl transferase 1 |
|
affects response to substance |
ISO |
X |
61,634,964 |
61,638,247 |
RGD:6480464 |
CTD |
| G |
Scg5 |
secretogranin V (7B2 protein) |
|
affects response to substance |
ISO |
3 |
99,629,194 |
99,674,523 |
RGD:6480464 |
CTD |
| G |
Serpinb2 |
serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
|
affects response to substance |
ISO |
13 |
13,632,596 |
13,641,605 |
RGD:6480464 |
CTD |
| G |
Serpine1 |
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
|
affects response to substance |
ISO |
12 |
20,931,996 |
20,942,374 |
RGD:6480464 |
CTD |
| G |
Sgk1 |
serum/glucocorticoid regulated kinase 1 |
|
increases expression |
ISO |
1 |
23,501,257 |
23,506,651 |
RGD:6480464 |
CTD |
| G |
Sgk1 |
serum/glucocorticoid regulated kinase 1 |
|
multiple interactions |
ISO |
1 |
23,501,257 |
23,506,651 |
RGD:6480464 |
CTD |
| G |
Sh3bp5 |
SH3-domain binding protein 5 (BTK-associated) |
|
affects response to substance |
ISO |
16 |
6,822,512 |
6,888,922 |
RGD:6480464 |
CTD |
| G |
Slc16a6 |
solute carrier family 16, member 6 (monocarboxylic acid transporter 7) |
|
affects response to substance |
ISO |
10 |
98,853,289 |
98,875,189 |
RGD:6480464 |
CTD |
| G |
Slc1a1 |
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
|
affects response to substance |
ISO |
1 |
232,469,746 |
232,549,584 |
RGD:6480464 |
CTD |
| G |
Slc27a3 |
solute carrier family 27 (fatty acid transporter), member 3 |
|
affects response to substance |
ISO |
2 |
182,643,984 |
182,648,652 |
RGD:6480464 |
CTD |
| G |
Smpdl3a |
sphingomyelin phosphodiesterase, acid-like 3A |
|
affects response to substance |
ISO |
20 |
36,821,916 |
36,844,891 |
RGD:6480464 |
CTD |
| G |
Sod1 |
superoxide dismutase 1, soluble |
|
increases expression |
ISO |
11 |
29,810,766 |
29,816,342 |
RGD:6480464 |
CTD |
| G |
Sod2 |
superoxide dismutase 2, mitochondrial |
|
affects response to substance |
ISO |
1 |
41,862,997 |
41,870,327 |
RGD:6480464 |
CTD |
| G |
Sorbs1 |
sorbin and SH3 domain containing 1 |
|
affects response to substance |
ISO |
1 |
245,419,532 |
245,527,846 |
RGD:6480464 |
CTD |
| G |
Sort1 |
sortilin 1 |
|
affects response to substance |
ISO |
2 |
203,853,009 |
203,931,559 |
RGD:6480464 |
CTD |
| G |
Srgn |
serglycin |
|
affects response to substance |
ISO |
20 |
29,746,729 |
29,761,072 |
RGD:6480464 |
CTD |
| G |
Srsf1 |
serine/arginine-rich splicing factor 1 |
|
affects response to substance |
ISO |
10 |
76,339,824 |
76,344,552 |
RGD:6480464 |
CTD |
| G |
Srxn1 |
sulfiredoxin 1 |
|
increases expression |
ISO |
3 |
142,457,352 |
142,462,725 |
RGD:6480464 |
CTD |
| G |
ST7 |
suppression of tumorigenicity 7 |
|
affects response to substance |
ISO |
4 |
43,357,517 |
43,604,941 |
RGD:6480464 |
CTD |
| G |
Stc2 |
stanniocalcin 2 |
|
affects response to substance |
ISO |
10 |
16,514,603 |
16,524,369 |
RGD:6480464 |
CTD |
| G |
Sub1 |
SUB1 homolog (S. cerevisiae) |
|
increases expression |
ISO |
2 |
61,418,076 |
61,430,139 |
RGD:6480464 |
CTD |
| G |
Sybu |
syntabulin (syntaxin-interacting) |
|
affects response to substance |
ISO |
7 |
80,551,448 |
80,636,458 |
RGD:6480464 |
CTD |
| G |
Tdrd3 |
tudor domain containing 3 |
|
affects response to substance |
ISO |
15 |
69,605,244 |
69,739,566 |
RGD:6480464 |
CTD |
| G |
Tfap2a |
transcription factor AP-2 alpha |
|
affects response to substance |
ISO |
17 |
30,017,580 |
30,034,852 |
RGD:6480464 |
CTD |
| G |
Tff3 |
trefoil factor 3, intestinal |
|
affects response to substance |
ISO |
20 |
9,469,888 |
9,474,604 |
RGD:6480464 |
CTD |
| G |
Tfpi |
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
|
affects response to substance |
ISO |
3 |
67,654,389 |
67,697,178 |
RGD:6480464 |
CTD |
| G |
Tfpi2 |
tissue factor pathway inhibitor 2 |
|
affects response to substance |
ISO |
4 |
28,807,080 |
28,811,502 |
RGD:6480464 |
CTD |
| G |
Tgds |
TDP-glucose 4,6-dehydratase |
|
affects response to substance |
ISO |
15 |
102,906,505 |
102,927,476 |
RGD:6480464 |
CTD |
| G |
Tgfb1 |
transforming growth factor, beta 1 |
|
increases expression |
ISO |
1 |
80,894,705 |
80,911,020 |
RGD:6480464 |
CTD |
| G |
Tgfbi |
transforming growth factor, beta induced |
|
decreases expression |
ISO |
17 |
13,904,882 |
13,935,110 |
RGD:6480464 |
CTD |
| G |
Tgm2 |
transglutaminase 2, C polypeptide |
|
affects response to substance |
ISO |
3 |
148,832,866 |
148,862,385 |
RGD:6480464 |
CTD |
| G |
Tk1 |
thymidine kinase 1, soluble |
|
increases mutagenesis |
ISO |
|
|
|
RGD:6480464 |
CTD |
| G |
Tmem156 |
transmembrane protein 156 |
|
affects response to substance |
ISO |
14 |
45,925,110 |
45,954,140 |
RGD:6480464 |
CTD |
| G |
Tmem97 |
transmembrane protein 97 |
|
affects response to substance |
ISO |
10 |
64,652,641 |
64,661,724 |
RGD:6480464 |
CTD |
| G |
Tnfsf10 |
tumor necrosis factor (ligand) superfamily, member 10 |
|
multiple interactions |
ISO |
2 |
113,204,303 |
113,221,550 |
RGD:6480464 |
CTD |
| G |
Tp53 |
tumor protein p53 |
|
increases expression |
ISO |
10 |
56,399,721 |
56,411,150 |
RGD:6480464 |
CTD |
| G |
Tp53 |
tumor protein p53 |
|
increases expression |
ISO |
10 |
56,399,721 |
56,411,150 |
RGD:6480464 |
CTD |
| G |
Tp53 |
tumor protein p53 |
|
affects response to substance |
ISO |
10 |
56,399,721 |
56,411,150 |
RGD:6480464 |
CTD |
| G |
Tp53 |
tumor protein p53 |
|
multiple interactions |
ISO |
10 |
56,399,721 |
56,411,150 |
RGD:6480464 |
CTD |
| G |
Tp53 |
tumor protein p53 |
|
multiple interactions |
ISO |
10 |
56,399,721 |
56,411,150 |
RGD:6480464 |
CTD |
| G |
Tp53 |
tumor protein p53 |
|
multiple interactions |
ISO |
10 |
56,399,721 |
56,411,150 |
RGD:6480464 |
CTD |
| G |
Tp53 |
tumor protein p53 |
|
increases expression |
ISO |
10 |
56,399,721 |
56,411,150 |
RGD:6480464 |
CTD |
| G |
Tp53 |
tumor protein p53 |
|
increases expression |
ISO |
10 |
56,399,721 |
56,411,150 |
RGD:6480464 |
CTD |
| G |
Tp53 |
tumor protein p53 |
|
affects response to substance |
ISO |
10 |
56,399,721 |
56,411,150 |
RGD:6480464 |
CTD |
| G |
Tp53 |
tumor protein p53 |
|
multiple interactions |
ISO |
10 |
56,399,721 |
56,411,150 |
RGD:6480464 |
CTD |
| G |
Tp53 |
tumor protein p53 |
|
increases stability |
ISO |
10 |
56,399,721 |
56,411,150 |
RGD:6480464 |
CTD |
| G |
Tp73 |
tumor protein p73 |
|
increases expression |
ISO |
5 |
170,848,979 |
171,078,739 |
RGD:6480464 |
CTD |
| G |
Tp73 |
tumor protein p73 |
|
multiple interactions |
ISO |
5 |
170,848,979 |
171,078,739 |
RGD:6480464 |
CTD |
| G |
Tpd52 |
tumor protein D52 |
|
affects response to substance |
ISO |
2 |
94,850,203 |
94,880,802 |
RGD:6480464 |
CTD |
| G |
Triap1 |
TP53 regulated inhibitor of apoptosis 1 |
|
increases expression |
ISO |
12 |
42,535,655 |
42,538,148 |
RGD:6480464 |
CTD |
| G |
Triap1 |
TP53 regulated inhibitor of apoptosis 1 |
|
multiple interactions |
ISO |
12 |
42,535,655 |
42,538,148 |
RGD:6480464 |
CTD |
| G |
Trib2 |
tribbles homolog 2 (Drosophila) |
|
affects response to substance |
ISO |
6 |
39,474,243 |
39,496,718 |
RGD:6480464 |
CTD |
| G |
Trim2 |
tripartite motif-containing 2 |
|
affects response to substance |
ISO |
2 |
175,908,880 |
175,974,709 |
RGD:6480464 |
CTD |
| G |
Txnrd1 |
thioredoxin reductase 1 |
|
multiple interactions |
EXP |
7 |
23,055,544 |
23,093,815 |
RGD:6480464 |
CTD |
| G |
Tyms |
thymidylate synthetase |
|
increases expression |
ISO |
9 |
112,604,912 |
112,617,706 |
RGD:6480464 |
CTD |
| G |
Ubl3 |
ubiquitin-like 3 |
|
affects response to substance |
ISO |
12 |
7,019,485 |
7,063,818 |
RGD:6480464 |
CTD |
| G |
Uchl1 |
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
|
affects response to substance |
ISO |
14 |
44,114,392 |
44,124,947 |
RGD:6480464 |
CTD |
| G |
Umps |
uridine monophosphate synthetase |
|
decreases expression |
ISO |
11 |
68,619,835 |
68,630,244 |
RGD:6480464 |
CTD |
| G |
Ung |
uracil-DNA glycosylase |
|
decreases response to substance |
ISO |
12 |
43,520,629 |
43,528,873 |
RGD:6480464 |
CTD |
| G |
Wipi1 |
WD repeat domain, phosphoinositide interacting 1 |
|
affects response to substance |
ISO |
10 |
98,722,266 |
98,753,713 |
RGD:6480464 |
CTD |
| G |
Wnt5a |
wingless-type MMTV integration site family, member 5A |
|
affects response to substance |
ISO |
16 |
3,782,025 |
3,799,625 |
RGD:6480464 |
CTD |
| G |
Wtap |
Wilms tumor 1 associated protein |
|
affects response to substance |
ISO |
1 |
41,891,437 |
41,917,254 |
RGD:6480464 |
CTD |
| G |
Xdh |
xanthine dehydrogenase |
|
multiple interactions |
ISO |
6 |
21,417,685 |
21,590,015 |
RGD:6480464 |
CTD |
| G |
Xdh |
xanthine dehydrogenase |
|
decreases activity |
ISO |
6 |
21,417,685 |
21,590,015 |
RGD:6480464 |
CTD |
| G |
Xiap |
X-linked inhibitor of apoptosis |
|
affects response to substance |
ISO |
X |
3,011,520 |
3,047,798 |
RGD:6480464 |
CTD |
| G |
Xrcc4 |
X-ray repair complementing defective repair in Chinese hamster cells 4 |
|
decreases response to substance |
ISO |
2 |
19,904,490 |
20,158,358 |
RGD:6480464 |
CTD |
| G |
Zfp281 |
zinc finger protein 281 |
|
affects response to substance |
ISO |
13 |
49,700,599 |
49,704,316 |
RGD:6480464 |
CTD |
Term paths to the root
|