ONTOLOGY REPORT - ANNOTATIONS

Term:antimycin A
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Accession:CHEBI:22584 term browser browse the term
Definition:A nine-membered bis-lactone having methyl substituents at the 2- and 6-positions, an n-hexyl substituent at the 8-position, an acyloxy substituent at the 7-position and an aroylamido substituent at the 3-position. It is produced by Streptomyces bacteria and has found commercial use as a fish poison.
Synonyms:exact_synonym: (2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl 3-methylbutanoate
 related_synonym: Antimycin A1;   Antipiricullin;   C28H40N2O9;   Fintrol;   InChI=1S/C28H40N2O9/c1-6-7-8-9-11-20-25(39-22(32)14-16(2)3)18(5)38-28(36)23(17(4)37-27(20)35)30-26(34)19-12-10-13-21(24(19)33)29-15-31/h10,12-13,15-18,20,23,25,33H,6-9,11,14H2,1-5H3,(H,29,31)(H,30,34)/t17-,18+,20-,23+,25+/m1/s1;   InChIKey=UIFFUZWRFRDZJC-SBOOETFBSA-N;   Virosin;   [H]C(=O)Nc1cccc(C(=O)N[C@H]2[C@@H](C)OC(=O)[C@H](CCCCCC)[C@@H](OC(=O)CC(C)C)[C@H](C)OC2=O)c1O;   antimycin A1b
 xref_casrn: 1397-94-0;   642-15-9
 xref: Beilstein:72665 "Beilstein Registry Number";   ChEMBL:453667 "ChEMBL COMPOUND";   ChemIDplus:1397-94-0 "CAS Registry Number";   ChemIDplus:642-15-9 "CAS Registry Number";   KEGG COMPOUND:642-15-9 "CAS Registry Number"
 xref_mesh: MESH:D000968

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antimycin A term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Acox2 acyl-CoA oxidase 2, branched chain GBrowse link increases expression ISO 15 18,645,349 18,677,855 RGD:6480464 CTD
G Akr1b7 aldo-keto reductase family 1, member B7 GBrowse link increases expression ISO 4 61,794,352 61,806,916 RGD:6480464 CTD
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link decreases activity ISO 6 137,640,482 137,657,552 RGD:6480464 CTD
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link multiple interactions ISO 6 137,640,482 137,657,552 RGD:6480464 CTD
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 GBrowse link increases expression ISO 7 22,398,067 22,450,381 RGD:6480464 CTD
G Angptl6 angiopoietin-like 6 GBrowse link increases expression ISO 8 19,899,121 19,905,696 RGD:6480464 CTD
G Atf3 activating transcription factor 3 GBrowse link increases expression ISO 13 107,191,622 107,223,850 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link decreases response to substance ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link multiple interactions ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bnip3 BCL2/adenovirus E1B interacting protein 3 GBrowse link increases expression ISO 1 198,683,009 198,700,075 RGD:6480464 CTD
G Car6 carbonic anhydrase 6 GBrowse link increases expression ISO 5 167,332,219 167,350,880 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link decreases expression ISO 10 70,256,263 70,258,061 RGD:6480464 CTD
G Ccl3 chemokine (C-C motif) ligand 3 GBrowse link decreases expression ISO 10 71,744,559 71,746,109 RGD:6480464 CTD
G Ccl4 chemokine (C-C motif) ligand 4 GBrowse link decreases expression ISO 10 71,759,643 71,761,115 RGD:6480464 CTD
G Ccl5 chemokine (C-C motif) ligand 5 GBrowse link decreases expression ISO 10 71,605,791 71,610,330 RGD:6480464 CTD
G Ccna2 cyclin A2 GBrowse link multiple interactions ISO 2 123,062,752 123,069,085 RGD:6480464 CTD
G Ccna2 cyclin A2 GBrowse link decreases expression ISO 2 123,062,752 123,069,085 RGD:6480464 CTD
G Ccnb1 cyclin B1 GBrowse link multiple interactions ISO 2 31,574,600 31,581,784 RGD:6480464 CTD
G Ccnb1 cyclin B1 GBrowse link decreases expression ISO 2 31,574,600 31,581,784 RGD:6480464 CTD
G Cd14 CD14 molecule GBrowse link increases expression ISO 18 29,374,593 29,376,190 RGD:6480464 CTD
G Cd34 CD34 molecule GBrowse link decreases expression ISO 13 110,877,594 110,896,722 RGD:6480464 CTD
G Cd38 CD38 molecule GBrowse link increases expression ISO 14 72,320,479 72,360,329 RGD:6480464 CTD
G Cd68 Cd68 molecule GBrowse link increases expression ISO 10 56,481,701 56,483,580 RGD:6480464 CTD
G Chchd10 coiled-coil-helix-coiled-coil-helix domain containing 10 GBrowse link increases expression ISO 20 13,124,662 13,126,461 RGD:6480464 CTD
G Col16a1 collagen, type XVI, alpha 1 GBrowse link decreases expression ISO 5 149,072,905 149,126,350 RGD:6480464 CTD
G Cox6a2 cytochrome c oxidase subunit VIa polypeptide 2 GBrowse link increases expression ISO 1 187,464,579 187,465,301 RGD:6480464 CTD
G Cp ceruloplasmin (ferroxidase) GBrowse link decreases expression ISO 2 105,086,278 105,135,367 RGD:6480464 CTD
G Cp ceruloplasmin (ferroxidase) GBrowse link increases degradation ISO 2 105,086,278 105,135,367 RGD:6480464 CTD
G Cth cystathionase (cystathionine gamma-lyase) GBrowse link increases expression ISO 2 256,056,562 256,082,248 RGD:6480464 CTD
G Cycs cytochrome c, somatic GBrowse link affects localization ISO 4 78,825,878 78,827,978 RGD:6480464 CTD
G Cycs cytochrome c, somatic GBrowse link multiple interactions ISO 4 78,825,878 78,827,978 RGD:6480464 CTD
G Ddit3 DNA-damage inducible transcript 3 GBrowse link increases expression EXP 7 67,247,749 67,252,571 RGD:6480464 CTD
G Ddit3 DNA-damage inducible transcript 3 GBrowse link increases expression ISO 7 67,247,749 67,252,571 RGD:6480464 CTD
G E2f7 E2F transcription factor 7 GBrowse link decreases expression ISO 7 49,689,755 49,751,823 RGD:6480464 CTD
G Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) GBrowse link multiple interactions ISO 12 1,459,046 1,500,042 RGD:6480464 CTD
G Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) GBrowse link decreases localization ISO 12 1,459,046 1,500,042 RGD:6480464 CTD
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 GBrowse link increases expression ISO 3 3,564,380 3,569,801 RGD:6480464 CTD
G Epas1 endothelial PAS domain protein 1 GBrowse link multiple interactions EXP 6 10,203,108 10,297,215 RGD:6480464 CTD
G Ero1l ERO1-like (S. cerevisiae) GBrowse link increases expression ISO 15 21,169,438 21,205,536 RGD:6480464 CTD
G Fas Fas (TNF receptor superfamily, member 6) GBrowse link decreases expression ISO 1 238,259,443 238,274,745 RGD:6480464 CTD
G Fgf1 fibroblast growth factor 1 (acidic) GBrowse link decreases expression ISO 18 31,785,480 31,806,452 RGD:6480464 CTD
G Gadd45a growth arrest and DNA-damage-inducible, alpha GBrowse link increases expression ISO 4 96,649,941 96,652,243 RGD:6480464 CTD
G Gch1 GTP cyclohydrolase 1 GBrowse link increases expression ISO 15 23,023,996 23,139,794 RGD:6480464 CTD
G Gsta1 glutathione S-transferase alpha 1 GBrowse link increases expression ISO 9 20,051,501 20,068,146 RGD:6480464 CTD
G Gsta2 glutathione S-transferase alpha 2 GBrowse link increases expression ISO 8 83,299,249 83,312,958 RGD:6480464 CTD
G Hif1a hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) GBrowse link affects expression EXP 6 96,419,024 96,463,891 RGD:6480464 CTD
G Hspa5 heat shock protein 5 GBrowse link increases expression EXP 3 13,783,825 13,788,022 RGD:6480464 CTD
G Htra1 HtrA serine peptidase 1 GBrowse link increases expression ISO 1 190,257,899 190,308,325 RGD:6480464 CTD
G Icam1 intercellular adhesion molecule 1 GBrowse link multiple interactions ISO 8 20,040,177 20,051,939 RGD:6480464 CTD
G Icam1 intercellular adhesion molecule 1 GBrowse link decreases expression ISO 8 20,040,177 20,051,939 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link multiple interactions ISO 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il6r interleukin 6 receptor GBrowse link decreases expression ISO 2 182,078,049 182,128,135 RGD:6480464 CTD
G Itgb7 integrin, beta 7 GBrowse link increases expression ISO 7 140,971,310 140,984,091 RGD:6480464 CTD
G Jun jun proto-oncogene GBrowse link multiple interactions ISO 5 115,358,166 115,361,259 RGD:6480464 CTD
G Jun jun proto-oncogene GBrowse link increases expression ISO 5 115,358,166 115,361,259 RGD:6480464 CTD
G Lsm6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) GBrowse link decreases expression ISO 19 30,877,859 30,893,927 RGD:6480464 CTD
G Mapk14 mitogen activated protein kinase 14 GBrowse link multiple interactions ISO 20 6,939,249 7,000,378 RGD:6480464 CTD
G Mmp13 matrix metallopeptidase 13 GBrowse link increases expression ISO 8 4,158,887 4,169,166 RGD:6480464 CTD
G Mmp2 matrix metallopeptidase 2 GBrowse link multiple interactions ISO 19 15,246,036 15,275,061 RGD:6480464 CTD
G Mmp2 matrix metallopeptidase 2 GBrowse link increases activity ISO 19 15,246,036 15,275,061 RGD:6480464 CTD
G Ndrg1 N-myc downstream regulated 1 GBrowse link increases expression ISO 7 104,302,038 104,344,842 RGD:6480464 CTD
G Nrp1 neuropilin 1 GBrowse link decreases expression ISO 19 58,332,004 58,487,686 RGD:6480464 CTD
G Nt5e 5' nucleotidase, ecto GBrowse link increases expression ISO 8 93,591,630 93,635,481 RGD:6480464 CTD
G Nupr1 nuclear protein, transcriptional regulator, 1 GBrowse link increases expression ISO 1 185,770,310 185,772,313 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link increases cleavage ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link multiple interactions ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Ppl periplakin GBrowse link decreases expression ISO 10 10,566,823 10,612,474 RGD:6480464 CTD
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A GBrowse link increases expression ISO 1 95,994,023 95,997,080 RGD:6480464 CTD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link increases expression ISO 13 64,427,288 64,432,978 RGD:6480464 CTD
G Rbl1 retinoblastoma-like 1 (p107) GBrowse link decreases expression ISO 3 147,734,622 147,796,630 RGD:6480464 CTD
G Rnd1 Rho family GTPase 1 GBrowse link increases expression ISO 7 137,418,519 137,425,590 RGD:6480464 CTD
G Rrm2 ribonucleotide reductase M2 GBrowse link decreases expression ISO 6 42,350,541 42,356,748 RGD:6480464 CTD
G Snai2 snail homolog 2 (Drosophila) increases expression ISO RGD:6480464 CTD
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link multiple interactions ISO 1 41,862,997 41,870,327 RGD:6480464 CTD
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link multiple interactions EXP 1 41,862,997 41,870,327 RGD:6480464 CTD
G Sqstm1 sequestosome 1 GBrowse link increases expression ISO 10 35,751,300 35,762,630 RGD:6480464 CTD
G Star steroidogenic acute regulatory protein GBrowse link decreases expression ISO 16 70,642,580 70,647,203 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnxb tenascin XB GBrowse link decreases expression ISO 20 4,133,875 4,178,049 RGD:6480464 CTD
G Tnxb tenascin XB GBrowse link decreases expression ISO 20 4,133,875 4,178,049 RGD:6480464 CTD
G Trib3 tribbles homolog 3 (Drosophila) GBrowse link increases expression ISO 3 142,664,641 142,670,135 RGD:6480464 CTD
G Trip12 thyroid hormone receptor interactor 12 GBrowse link decreases expression ISO 9 83,961,411 84,085,077 RGD:6480464 CTD
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) GBrowse link increases expression ISO 1 157,925,514 157,928,222 RGD:6480464 CTD
G Uts2 urotensin 2 GBrowse link increases expression ISO 5 168,143,315 168,148,700 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link decreases expression ISO 9 10,520,730 10,536,071 RGD:6480464 CTD
G Wnt7a wingless-type MMTV integration site family, member 7A GBrowse link increases expression ISO 4 125,541,281 125,586,167 RGD:6480464 CTD
G Xbp1 X-box binding protein 1 GBrowse link increases expression EXP 14 86,151,910 86,156,975 RGD:6480464 CTD
G Zhx1 zinc fingers and homeoboxes 1 GBrowse link decreases expression ISO 7 94,753,899 94,775,384 RGD:6480464 CTD
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 492574
    role 482262
      biological role 480454
        antimicrobial agent 45711
          antibiotic 12604
            antimycin A 90
Path 2
Term Annotations click to browse term
  CHEBI ontology 492574
    subatomic particle 491537
      composite particle 491537
        hadron 491537
          baryon 491537
            nucleon 491537
              atomic nucleus 491537
                atom 491537
                  main group element atom 461203
                    p-block element atom 458699
                      carbon group element atom 410677
                        carbon atom 407233
                          organic molecular entity 407226
                            organic group 167766
                              organic divalent group 166601
                                organodiyl group 166601
                                  carbonyl group 166291
                                    carbonyl compound 166291
                                      carboxylic acid 121484
                                        carboacyl group 40976
                                          univalent carboacyl group 40976
                                            carbamoyl group 37195
                                              carboxamide 37186
                                                monocarboxylic acid amide 24330
                                                  arenecarboxamide 405
                                                    benzamides 405
                                                      antimycin A 90
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