ONTOLOGY REPORT - ANNOTATIONS
| Term: | NADP(+) |
|
| Accession: | CHEBI:18009
|
browse the term
|
| Definition: | A NAD(P)(+) that has formula C21H29N7O17P3. |
| Synonyms: | exact_synonym: | 2'-O-phosphonoadenosine 5'-{3-[1-(3-carbamoylpyridinio)-1,4-anhydro-D-ribitol-5-yl] dihydrogen diphosphate} |
| | related_synonym: | C21H29N7O17P3; InChI=1S/C21H28N7O17P3/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39)/p+1/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1; InChIKey=XJLXINKUBYWONI-NNYOXOHSSA-O; NC(=O)c1ccc[n+](c1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](OP(O)(O)=O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O; Nicotinamide adenine dinucleotide phosphate; TPN; Triphosphopyridine nucleotide; beta-Nicotinamide adenine dinucleotide phosphate; oxidized nicotinamide-adenine dinucleotide phosphate |
| | alt_id: | CHEBI:13398; CHEBI:21903; CHEBI:7424 |
| | xref_casrn: | 53-59-8 |
| | xref: | Beilstein:3645734 "Beilstein Registry Number"; COMe:MOL000029 "COMe"; KEGG COMPOUND:53-59-8 "CAS Registry Number"; KEGG COMPOUND:C00006 "KEGG COMPOUND" |
| | xref_mesh: | MESH:D009249 |
| | cyclic_relationship: | is_conjugate_acid_of CHEBI:44409; is_conjugate_acid_of CHEBI:58349 |
|
|
NADP(+)
|
| G |
Ache |
acetylcholinesterase |
|
multiple interactions |
ISO |
5 |
137,729,505 |
137,735,691 |
RGD:6480464 |
CTD |
| G |
Akr1a1 |
aldo-keto reductase family 1, member A1 (aldehyde reductase) |
|
multiple interactions |
ISO |
4 |
116,309,115 |
116,324,256 |
RGD:6480464 |
CTD |
| G |
Akr1a1 |
aldo-keto reductase family 1, member A1 (aldehyde reductase) |
|
multiple interactions |
ISO |
4 |
116,309,115 |
116,324,256 |
RGD:6480464 |
CTD |
| G |
Akr1b10 |
aldo-keto reductase family 1, member B10 (aldose reductase) |
|
multiple interactions |
ISO |
6 |
34,334,247 |
34,346,949 |
RGD:6480464 |
CTD |
| G |
Akr1b10 |
aldo-keto reductase family 1, member B10 (aldose reductase) |
|
decreases reduction |
ISO |
6 |
34,334,247 |
34,346,949 |
RGD:6480464 |
CTD |
| G |
Akr1b10 |
aldo-keto reductase family 1, member B10 (aldose reductase) |
|
multiple interactions |
ISO |
6 |
34,334,247 |
34,346,949 |
RGD:6480464 |
CTD |
| G |
Akr1b3 |
aldo-keto reductase family 1, member B3 (aldose reductase) |
|
multiple interactions |
ISO |
6 |
34,253,930 |
34,267,489 |
RGD:6480464 |
CTD |
| G |
Akr1b8 |
aldo-keto reductase family 1, member B8 |
|
multiple interactions |
ISO |
6 |
34,304,164 |
34,318,454 |
RGD:6480464 |
CTD |
| G |
Akr1c14 |
aldo-keto reductase family 1, member C14 |
|
multiple interactions |
ISO |
13 |
4,058,837 |
4,089,668 |
RGD:6480464 |
CTD |
| G |
Akr1c18 |
aldo-keto reductase family 1, member C18 |
|
multiple interactions |
ISO |
13 |
4,131,873 |
4,149,877 |
RGD:6480464 |
CTD |
| G |
Akr1c18 |
aldo-keto reductase family 1, member C18 |
|
multiple interactions |
ISO |
13 |
4,131,873 |
4,149,877 |
RGD:6480464 |
CTD |
| G |
Akr1c21 |
aldo-keto reductase family 1, member C21 |
|
multiple interactions |
ISO |
13 |
4,573,321 |
4,585,789 |
RGD:6480464 |
CTD |
| G |
Akr1c21 |
aldo-keto reductase family 1, member C21 |
|
multiple interactions |
ISO |
13 |
4,573,321 |
4,585,789 |
RGD:6480464 |
CTD |
| G |
Akr1c6 |
aldo-keto reductase family 1, member C6 |
|
multiple interactions |
ISO |
13 |
4,433,589 |
4,456,776 |
RGD:6480464 |
CTD |
| G |
Akr7a5 |
aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase) |
|
multiple interactions |
ISO |
4 |
138,866,659 |
138,874,701 |
RGD:6480464 |
CTD |
| G |
Aldh2 |
aldehyde dehydrogenase 2, mitochondrial |
|
multiple interactions |
EXP |
5 |
122,017,696 |
122,043,833 |
RGD:6480464 |
CTD |
| G |
Aldh3a1 |
aldehyde dehydrogenase family 3, subfamily A1 |
|
multiple interactions |
ISO |
11 |
61,022,244 |
61,031,920 |
RGD:6480464 |
CTD |
| G |
Aldh3a1 |
aldehyde dehydrogenase family 3, subfamily A1 |
|
increases activity |
EXP |
11 |
61,022,244 |
61,031,920 |
RGD:6480464 |
CTD |
| G |
Cbr1 |
carbonyl reductase 1 |
|
multiple interactions |
ISO |
16 |
93,608,082 |
93,610,594 |
RGD:6480464 |
CTD |
| G |
Cbr2 |
carbonyl reductase 2 |
|
multiple interactions |
ISO |
11 |
120,590,799 |
120,593,335 |
RGD:6480464 |
CTD |
| G |
Cd38 |
CD38 antigen |
|
multiple interactions |
EXP |
5 |
44,260,066 |
44,303,613 |
RGD:6480464 |
CTD |
| G |
Cyb5 |
cytochrome b-5 |
|
multiple interactions |
ISO |
18 |
85,020,806 |
85,049,255 |
RGD:6480464 |
CTD |
| G |
Cybb |
cytochrome b-245, beta polypeptide |
|
multiple interactions |
EXP |
X |
9,012,378 |
9,046,450 |
RGD:6480464 |
CTD |
| G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
|
multiple interactions |
ISO |
9 |
57,535,735 |
57,551,629 |
RGD:6480464 |
CTD |
| G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
|
multiple interactions |
ISO |
9 |
57,524,744 |
57,531,462 |
RGD:6480464 |
CTD |
| G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
|
multiple interactions |
ISO |
9 |
57,524,744 |
57,531,462 |
RGD:6480464 |
CTD |
| G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
|
multiple interactions |
ISO |
17 |
80,106,293 |
80,114,381 |
RGD:6480464 |
CTD |
| G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
|
multiple interactions |
ISO |
17 |
80,106,293 |
80,114,381 |
RGD:6480464 |
CTD |
| G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
|
multiple interactions |
ISO |
17 |
80,106,293 |
80,114,381 |
RGD:6480464 |
CTD |
| G |
Cyp2b10 |
cytochrome P450, family 2, subfamily b, polypeptide 10 |
|
multiple interactions |
ISO |
7 |
26,682,683 |
26,711,643 |
RGD:6480464 |
CTD |
| G |
Cyp2b10 |
cytochrome P450, family 2, subfamily b, polypeptide 10 |
|
multiple interactions |
ISO |
7 |
26,682,683 |
26,711,643 |
RGD:6480464 |
CTD |
| G |
Cyp2c50 |
cytochrome P450, family 2, subfamily c, polypeptide 50 |
|
multiple interactions |
ISO |
19 |
40,164,169 |
40,188,445 |
RGD:6480464 |
CTD |
| G |
Cyp2c50 |
cytochrome P450, family 2, subfamily c, polypeptide 50 |
|
multiple interactions |
ISO |
19 |
40,164,169 |
40,188,445 |
RGD:6480464 |
CTD |
| G |
Cyp2c55 |
cytochrome P450, family 2, subfamily c, polypeptide 55 |
|
multiple interactions |
ISO |
19 |
39,081,509 |
39,117,177 |
RGD:6480464 |
CTD |
| G |
Cyp2c65 |
cytochrome P450, family 2, subfamily c, polypeptide 65 |
|
multiple interactions |
ISO |
19 |
39,135,496 |
39,168,438 |
RGD:6480464 |
CTD |
| G |
Cyp2c65 |
cytochrome P450, family 2, subfamily c, polypeptide 65 |
|
multiple interactions |
ISO |
19 |
39,135,496 |
39,168,438 |
RGD:6480464 |
CTD |
| G |
Cyp2d22 |
cytochrome P450, family 2, subfamily d, polypeptide 22 |
|
multiple interactions |
ISO |
15 |
82,200,957 |
82,210,690 |
RGD:6480464 |
CTD |
| G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
|
multiple interactions |
ISO |
7 |
147,949,731 |
147,960,880 |
RGD:6480464 |
CTD |
| G |
Cyp3a41a |
cytochrome P450, family 3, subfamily a, polypeptide 41A |
|
multiple interactions |
ISO |
5 |
146,505,624 |
146,531,712 |
RGD:6480464 |
CTD |
| G |
Dhrs2 |
dehydrogenase/reductase member 2 |
|
multiple interactions |
ISO |
14 |
55,840,844 |
55,860,277 |
RGD:6480464 |
CTD |
| G |
Fasl |
Fas ligand (TNF superfamily, member 6) |
|
multiple interactions |
EXP |
1 |
163,710,820 |
163,718,626 |
RGD:6480464 |
CTD |
| G |
Fmo1 |
flavin containing monooxygenase 1 |
|
multiple interactions |
ISO |
1 |
164,759,692 |
164,796,679 |
RGD:6480464 |
CTD |
| G |
Fmo1 |
flavin containing monooxygenase 1 |
|
multiple interactions |
ISO |
1 |
164,759,692 |
164,796,679 |
RGD:6480464 |
CTD |
| G |
G6pdx |
glucose-6-phosphate dehydrogenase X-linked |
|
increases reduction |
ISO |
X |
71,654,825 |
71,674,500 |
RGD:6480464 |
CTD |
| G |
G6pdx |
glucose-6-phosphate dehydrogenase X-linked |
|
increases expression |
ISO |
X |
71,654,825 |
71,674,500 |
RGD:6480464 |
CTD |
| G |
Gsr |
glutathione reductase |
|
multiple interactions |
ISO |
8 |
34,763,710 |
34,808,634 |
RGD:6480464 |
CTD |
| G |
Gsr |
glutathione reductase |
|
multiple interactions |
ISO |
8 |
34,763,710 |
34,808,634 |
RGD:6480464 |
CTD |
| G |
Gsr |
glutathione reductase |
|
multiple interactions |
ISO |
8 |
34,763,710 |
34,808,634 |
RGD:6480464 |
CTD |
| G |
Gsr |
glutathione reductase |
|
multiple interactions |
EXP |
8 |
34,763,710 |
34,808,634 |
RGD:6480464 |
CTD |
| G |
Gsr |
glutathione reductase |
|
increases oxidation |
EXP |
8 |
34,763,710 |
34,808,634 |
RGD:6480464 |
CTD |
| G |
Hsd17b1 |
hydroxysteroid (17-beta) dehydrogenase 1 |
|
multiple interactions |
ISO |
11 |
100,939,725 |
100,941,819 |
RGD:6480464 |
CTD |
| G |
Hsd17b3 |
hydroxysteroid (17-beta) dehydrogenase 3 |
|
multiple interactions |
ISO |
13 |
64,159,582 |
64,190,509 |
RGD:6480464 |
CTD |
| G |
Hsd17b3 |
hydroxysteroid (17-beta) dehydrogenase 3 |
|
multiple interactions |
ISO |
13 |
64,159,582 |
64,190,509 |
RGD:6480464 |
CTD |
| G |
Ins1 |
insulin I |
|
multiple interactions |
ISO |
19 |
52,338,813 |
52,339,966 |
RGD:6480464 |
CTD |
| G |
Kcnab2 |
potassium voltage-gated channel, shaker-related subfamily, beta member 2 |
|
affects binding |
ISO |
4 |
151,764,853 |
151,851,588 |
RGD:6480464 |
CTD |
| G |
Kcnab2 |
potassium voltage-gated channel, shaker-related subfamily, beta member 2 |
|
multiple interactions |
ISO |
4 |
151,764,853 |
151,851,588 |
RGD:6480464 |
CTD |
| G |
Keap1 |
kelch-like ECH-associated protein 1 |
|
affects abundance |
EXP |
9 |
21,034,174 |
21,043,776 |
RGD:6480464 |
CTD |
| G |
Nat1 |
N-acetyl transferase 1 |
|
multiple interactions |
ISO |
8 |
70,014,657 |
70,016,003 |
RGD:6480464 |
CTD |
| G |
Nat2 |
N-acetyltransferase 2 (arylamine N-acetyltransferase) |
|
multiple interactions |
ISO |
8 |
70,018,774 |
70,026,479 |
RGD:6480464 |
CTD |
| G |
Nfe2l2 |
nuclear factor, erythroid derived 2, like 2 |
|
affects abundance |
EXP |
2 |
75,513,576 |
75,542,698 |
RGD:6480464 |
CTD |
| G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
|
multiple interactions |
ISO |
8 |
109,912,125 |
109,927,105 |
RGD:6480464 |
CTD |
| G |
Nqo1 |
NAD(P)H dehydrogenase, quinone 1 |
|
multiple interactions |
ISO |
8 |
109,912,125 |
109,927,105 |
RGD:6480464 |
CTD |
| G |
Parp1 |
poly (ADP-ribose) polymerase family, member 1 |
|
multiple interactions |
ISO |
1 |
182,499,106 |
182,531,385 |
RGD:6480464 |
CTD |
| G |
Pgd |
phosphogluconate dehydrogenase |
|
increases expression |
ISO |
4 |
148,524,094 |
148,540,816 |
RGD:6480464 |
CTD |
| G |
Por |
P450 (cytochrome) oxidoreductase |
|
multiple interactions |
ISO |
5 |
136,165,084 |
136,211,195 |
RGD:6480464 |
CTD |
| G |
Por |
P450 (cytochrome) oxidoreductase |
|
multiple interactions |
ISO |
5 |
136,165,084 |
136,211,195 |
RGD:6480464 |
CTD |
| G |
Por |
P450 (cytochrome) oxidoreductase |
|
multiple interactions |
ISO |
5 |
136,165,084 |
136,211,195 |
RGD:6480464 |
CTD |
| G |
Por |
P450 (cytochrome) oxidoreductase |
|
multiple interactions |
ISO |
5 |
136,165,084 |
136,211,195 |
RGD:6480464 |
CTD |
| G |
Por |
P450 (cytochrome) oxidoreductase |
|
multiple interactions |
ISO |
5 |
136,165,084 |
136,211,195 |
RGD:6480464 |
CTD |
| G |
Por |
P450 (cytochrome) oxidoreductase |
|
increases metabolic processing |
EXP |
5 |
136,165,084 |
136,211,195 |
RGD:6480464 |
CTD |
| G |
Por |
P450 (cytochrome) oxidoreductase |
|
increases metabolic processing |
ISO |
5 |
136,165,084 |
136,211,195 |
RGD:6480464 |
CTD |
| G |
Por |
P450 (cytochrome) oxidoreductase |
|
multiple interactions |
EXP |
5 |
136,165,084 |
136,211,195 |
RGD:6480464 |
CTD |
| G |
Prnp |
prion protein |
|
multiple interactions |
EXP |
2 |
131,735,664 |
131,764,167 |
RGD:6480464 |
CTD |
| G |
Prnp |
prion protein |
|
multiple interactions |
ISO |
2 |
131,735,664 |
131,764,167 |
RGD:6480464 |
CTD |
| G |
Ptgr1 |
prostaglandin reductase 1 |
|
multiple interactions |
ISO |
4 |
58,978,462 |
58,999,950 |
RGD:6480464 |
CTD |
| G |
Ptgr1 |
prostaglandin reductase 1 |
|
multiple interactions |
ISO |
4 |
58,978,462 |
58,999,950 |
RGD:6480464 |
CTD |
| G |
Sult1a1 |
sulfotransferase family 1A, phenol-preferring, member 1 |
|
multiple interactions |
ISO |
7 |
133,816,384 |
133,819,871 |
RGD:6480464 |
CTD |
| G |
Taldo1 |
transaldolase 1 |
|
decreases abundance |
EXP |
7 |
148,578,059 |
148,588,875 |
RGD:6480464 |
CTD |
| G |
Taldo1 |
transaldolase 1 |
|
multiple interactions |
EXP |
7 |
148,578,059 |
148,588,875 |
RGD:6480464 |
CTD |
| G |
Tdo2 |
tryptophan 2,3-dioxygenase |
|
affects abundance |
ISO |
3 |
81,762,334 |
81,779,650 |
RGD:6480464 |
CTD |
| G |
Txn1 |
thioredoxin 1 |
|
multiple interactions |
ISO |
4 |
57,956,245 |
57,969,283 |
RGD:6480464 |
CTD |
| G |
Txnrd1 |
thioredoxin reductase 1 |
|
multiple interactions |
ISO |
10 |
82,296,696 |
82,360,469 |
RGD:6480464 |
CTD |
| G |
Txnrd1 |
thioredoxin reductase 1 |
|
multiple interactions |
ISO |
10 |
82,296,696 |
82,360,469 |
RGD:6480464 |
CTD |
| G |
Txnrd1 |
thioredoxin reductase 1 |
|
multiple interactions |
ISO |
10 |
82,296,696 |
82,360,469 |
RGD:6480464 |
CTD |
| G |
Txnrd1 |
thioredoxin reductase 1 |
|
increases reduction |
ISO |
10 |
82,296,696 |
82,360,469 |
RGD:6480464 |
CTD |
| G |
Txnrd1 |
thioredoxin reductase 1 |
|
multiple interactions |
ISO |
10 |
82,296,696 |
82,360,469 |
RGD:6480464 |
CTD |
| G |
Txnrd1 |
thioredoxin reductase 1 |
|
multiple interactions |
ISO |
10 |
82,296,696 |
82,360,469 |
RGD:6480464 |
CTD |
Term paths to the root
|