ONTOLOGY REPORT - ANNOTATIONS
| Term: | chloramphenicol |
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| Accession: | CHEBI:17698
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browse the term
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| Definition: | An organochlorine compound that is dichloro-substituted acetamide containing a nitrobenzene ring, an amide bond and two alcohol functions. |
| Synonyms: | exact_synonym: | 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide |
| | related_synonym: | C11H12Cl2N2O5; Chloramex; Chlorocid; Chlorocol; Chloromycetin; D-(-)-2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenylethyl)acetamide; D-(-)-threo-1-p-nitrophenyl-2-dichloroacetylamino-1,3-propanediol; Fenicol; Globenicol; Halomycetin; InChI=1S/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9-/m1/s1; InChIKey=WIIZWVCIJKGZOK-RKDXNWHRSA-N; OC[C@@H](NC(=O)C(Cl)Cl)[C@H](O)c1ccc(cc1)[N+]([O-])=O; Oleomycetin; Sificetina; chloramphenicolum; cloramfenicol; laevomycetinum; levomicetina; levomycetin |
| | alt_id: | CHEBI:13965; CHEBI:23106; CHEBI:23108; CHEBI:3603; CHEBI:47327 |
| | xref_casrn: | 56-75-7 |
| | xref: | Beilstein:2225532 "Beilstein Registry Number"; ChEMBL:127340 "ChEMBL COMPOUND"; ChemIDplus:56-75-7 "CAS Registry Number"; CiteXplore:11468347 "PubMed citation"; CiteXplore:12217690 "PubMed citation"; CiteXplore:16659995 "PubMed citation"; CiteXplore:16897441 "PubMed citation"; CiteXplore:17217404 "PubMed citation"; CiteXplore:17692887 "PubMed citation"; CiteXplore:18559535 "PubMed citation"; CiteXplore:18657290 "PubMed citation"; CiteXplore:18794387 "PubMed citation"; CiteXplore:23142491 "PubMed citation"; CiteXplore:23317719 "PubMed citation"; CiteXplore:23395526 "PubMed citation"; CiteXplore:23494278 "PubMed citation"; CiteXplore:23512826 "PubMed citation"; CiteXplore:657786 "PubMed citation"; CiteXplore:6653106 "PubMed citation"; DrugBank:DB00446 "DrugBank"; KEGG COMPOUND:56-75-7 "CAS Registry Number"; KEGG COMPOUND:C00918 "KEGG COMPOUND"; KEGG DRUG:D00104 "KEGG DRUG" |
| | xref_mesh: | MESH:D002701 |
| | xref: | PDBeChem:CLM "PDBeChem"; Patent:GB795131 "Patent"; Patent:GB796901 "Patent"; Patent:US2483871 "Patent"; Patent:US2483884 "Patent"; Patent:US2483892 "Patent"; Patent:US2839577 "Patent"; Wikipedia:Chloramphenicol "Wikipedia" |
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chloramphenicol
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| G |
Alpl |
alkaline phosphatase, liver/bone/kidney |
|
increases expression |
ISO |
5 |
156,501,739 |
156,558,727 |
RGD:6480464 |
CTD |
| G |
Atg12 |
autophagy related 12 |
|
increases expression |
ISO |
18 |
40,933,793 |
40,943,970 |
RGD:6480464 |
CTD |
| G |
Casp3 |
caspase 3 |
|
multiple interactions |
ISO |
16 |
48,944,226 |
48,962,420 |
RGD:6480464 |
CTD |
| G |
Cat |
catalase |
|
increases expression |
ISO |
3 |
88,654,077 |
88,686,212 |
RGD:6480464 |
CTD |
| G |
Ccnb1 |
cyclin B1 |
|
multiple interactions |
ISO |
2 |
31,574,600 |
31,581,784 |
RGD:6480464 |
CTD |
| G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
|
multiple interactions |
ISO |
20 |
7,376,325 |
7,386,778 |
RGD:6480464 |
CTD |
| G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
|
decreases degradation |
ISO |
20 |
7,376,325 |
7,386,778 |
RGD:6480464 |
CTD |
| G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
|
increases expression |
ISO |
5 |
108,908,749 |
108,916,380 |
RGD:6480464 |
CTD |
| G |
Col1a1 |
collagen, type I, alpha 1 |
|
increases expression |
ISO |
10 |
83,622,438 |
83,639,368 |
RGD:6480464 |
CTD |
| G |
Esr1 |
estrogen receptor 1 |
|
increases expression |
ISO |
1 |
35,523,680 |
35,759,891 |
RGD:6480464 |
CTD |
| G |
Faslg |
Fas ligand (TNF superfamily, member 6) |
|
decreases expression |
ISO |
13 |
77,472,950 |
77,480,210 |
RGD:6480464 |
CTD |
| G |
Jun |
jun proto-oncogene |
|
multiple interactions |
ISO |
5 |
115,358,166 |
115,361,259 |
RGD:6480464 |
CTD |
| G |
Mmp10 |
matrix metallopeptidase 10 (stromelysin 2) |
|
decreases expression |
ISO |
8 |
4,367,842 |
4,375,737 |
RGD:6480464 |
CTD |
| G |
Mmp13 |
matrix metallopeptidase 13 |
|
multiple interactions |
ISO |
8 |
4,158,887 |
4,169,166 |
RGD:6480464 |
CTD |
| G |
Mmp13 |
matrix metallopeptidase 13 |
|
increases expression |
ISO |
8 |
4,158,887 |
4,169,166 |
RGD:6480464 |
CTD |
| G |
Mmp13 |
matrix metallopeptidase 13 |
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increases secretion |
ISO |
8 |
4,158,887 |
4,169,166 |
RGD:6480464 |
CTD |
| G |
Mmp3 |
matrix metallopeptidase 3 |
|
increases expression |
ISO |
8 |
4,315,601 |
4,329,146 |
RGD:6480464 |
CTD |
| G |
Mt-co1 |
mitochondrially encoded cytochrome c oxidase I |
|
decreases expression |
ISO |
MT |
5,323 |
6,867 |
RGD:6480464 |
CTD |
| G |
Mt-nd1 |
mitochondrially encoded NADH dehydrogenase 1 |
|
multiple interactions |
ISO |
MT |
2,740 |
3,694 |
RGD:6480464 |
CTD |
| G |
Mt-nd1 |
mitochondrially encoded NADH dehydrogenase 1 |
|
decreases expression |
ISO |
MT |
2,740 |
3,694 |
RGD:6480464 |
CTD |
| G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
|
multiple interactions |
ISO |
13 |
96,309,670 |
96,341,486 |
RGD:6480464 |
CTD |
| G |
Pgd |
phosphogluconate dehydrogenase |
|
decreases activity |
EXP |
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RGD:6480464 |
CTD |
| G |
Polg |
polymerase (DNA directed), gamma |
|
increases expression |
ISO |
1 |
135,197,075 |
135,212,178 |
RGD:6480464 |
CTD |
| G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
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multiple interactions |
ISO |
13 |
64,427,288 |
64,432,978 |
RGD:6480464 |
CTD |
| G |
Rrm2b |
ribonucleotide reductase M2 B (TP53 inducible) |
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increases expression |
ISO |
7 |
73,432,161 |
73,459,541 |
RGD:6480464 |
CTD |
| G |
Slc22a7 |
solute carrier family 22 (organic anion transporter), member 7 |
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multiple interactions |
ISO |
9 |
9,934,309 |
9,940,107 |
RGD:6480464 |
CTD |
| G |
Tfam |
transcription factor A, mitochondrial |
|
increases expression |
ISO |
20 |
18,100,629 |
18,112,682 |
RGD:6480464 |
CTD |
Term paths to the root
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