cerulenin - Ontology Report - Rat Genome Database

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ONTOLOGY REPORT - ANNOTATIONS

Term:	cerulenin	go back to main search page
Accession:	CHEBI:171741	browse the term
Definition:	An epoxydodecadienamide isolated from several species, including Acremonium, Acrocylindrum and Helicoceras. It inhibits the biosynthesis of several lipids by interfering with enzyme function.
Synonyms:	related_synonym:	(2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-carboxylic acid amide; (2R,3S)-3-((4E,7E)-nona-4,7-dienoyl)oxirane-2-carboxamide; C12H17NO3; InChI=1S/C12H17NO3/c1-2-3-4-5-6-7-8-9(14)10-11(16-10)12(13)15/h2-3,5-6,10-11H,4,7-8H2,1H3,(H2,13,15)/b3-2+,6-5+/t10-,11-/m1/s1; InChIKey=GVEZIHKRYBHEFX-NQQPLRFYSA-N; [H][C@]1(O[C@]1([H])C(=O)CC\\C=C\\C\\C=C\\C)C(N)=O
	alt_id:	CHEBI:29552
	xref_casrn:	17397-89-6
	xref:	Beilstein:4807182 "Beilstein Registry Number"; ChEMBL:171741 "ChEMBL COMPOUND"; ChemIDplus:17397-89-6 "CAS Registry Number"; DrugBank:DB01034 "DrugBank"; KEGG COMPOUND:17397-89-6 "CAS Registry Number"; KEGG COMPOUND:C12058 "KEGG COMPOUND"
	xref_mesh:	MESH:D002569

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cerulenin
	Symbol	Object Name	GBrowse	Qualifiers	Evidence	Chr	Start	Stop	Reference	Source
G	Agrp	agouti related protein homolog (mouse)		increases expression	ISO	19	35,386,682	35,388,274	RGD:6480464	CTD
G	Asip	agouti signaling protein		affects response to substance	ISO	3	145,445,175	145,536,831	RGD:6480464	CTD
G	Casp3	caspase 3		increases activity	ISO	16	48,944,226	48,962,420	RGD:6480464	CTD
G	Casp9	caspase 9, apoptosis-related cysteine peptidase		increases activity	ISO	5	160,704,234	160,721,796	RGD:6480464	CTD
G	Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha		decreases expression	ISO	1	87,626,111	87,627,499	RGD:6480464	CTD
G	Eif2a	eukaryotic translation initiation factor 2A		increases phosphorylation	ISO	2	147,870,265	147,903,411	RGD:6480464	CTD
G	Ern1	endoplasmic reticulum to nucleus signaling 1		multiple interactions	ISO	10	95,794,488	95,855,895	RGD:6480464	CTD
G	Fasn	fatty acid synthase		multiple interactions	ISO				RGD:6480464	CTD
G	Fasn	fatty acid synthase		decreases activity	ISO				RGD:6480464	CTD
G	Fasn	fatty acid synthase		decreases activity	ISO				RGD:6480464	CTD
G	Fasn	fatty acid synthase		decreases expression	ISO				RGD:6480464	CTD
G	Hnf4a	hepatocyte nuclear factor 4, alpha		multiple interactions	ISO	3	154,459,863	154,482,825	RGD:6480464	CTD
G	Lep	leptin		affects response to substance	ISO	4	55,943,837	55,945,938	RGD:6480464	CTD
G	Pparg	peroxisome proliferator-activated receptor gamma		decreases expression	ISO	4	151,492,220	151,617,331	RGD:6480464	CTD
G	Shbg	sex hormone binding globulin		multiple interactions	ISO	10	56,432,474	56,435,654	RGD:6480464	CTD
G	Xbp1	X-box binding protein 1		multiple interactions	ISO	14	86,151,910	86,156,975	RGD:6480464	CTD

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	492574
role	482262
biological role	480454
antimicrobial agent	45711
antibiotic	12604
cerulenin	16
Path 2
Term	Annotations
CHEBI ontology	492574
subatomic particle	491537
composite particle	491537
hadron	491537
baryon	491537
nucleon	491537
atomic nucleus	491537
atom	491537
main group element atom	461203
p-block element atom	458699
carbon group element atom	410677
carbon atom	407233
organic molecular entity	407226
organic group	167766
organic divalent group	166601
organodiyl group	166601
carbonyl group	166291
carbonyl compound	166291
carboxylic acid	121484
carboacyl group	40976
univalent carboacyl group	40976
carbamoyl group	37195
carboxamide	37186
monocarboxylic acid amide	24330
cerulenin	16