ONTOLOGY REPORT - ANNOTATIONS
| Term: | 3alpha-hydroxy-5beta-pregnan-20-one |
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| Accession: | CHEBI:1712
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browse the term
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| Definition: | A 3-hydroxy-5beta-pregnan-20-one that has formula C21H34O2. |
| Synonyms: | related_synonym: | (3alpha,5beta)-3-hydroxypregnan-20-one; 3alpha-Hydroxy-5beta-pregnane-20-one; C21H34O2; InChI=1S/C21H34O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h14-19,23H,4-12H2,1-3H3/t14-,15-,16+,17-,18+,19+,20+,21-/m1/s1; InChIKey=AURFZBICLPNKBZ-YZRLXODZSA-N; [H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@]([H])(C(C)=O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CC[C@@H](O)C2; eltanolona; eltanolone; eltanolonum; pregnan-3alpha-ol-20-one; pregnanolone |
| | xref_casrn: | 128-20-1 |
| | xref: | Beilstein:3211364 "Beilstein Registry Number"; ChEMBL:449429 "ChEMBL COMPOUND"; ChemIDplus:128-20-1 "CAS Registry Number"; KEGG COMPOUND:C05480 "KEGG COMPOUND" |
| | xref_mesh: | MESH:D011280 |
| | xref: | NIST Chemistry WebBook:128-20-1 "CAS Registry Number" |
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3alpha-hydroxy-5beta-pregnan-20-one
|
| G |
Akr1c1 |
aldo-keto reductase family 1, member C1 |
|
increases reduction |
ISO |
17 |
77,084,306 |
77,112,994 |
RGD:6480464 |
CTD |
| G |
Akr1c1 |
aldo-keto reductase family 1, member C1 |
|
affects metabolic processing |
ISO |
17 |
77,084,306 |
77,112,994 |
RGD:6480464 |
CTD |
| G |
Akr1c2 |
aldo-keto reductase family 1, member C2 |
|
increases reduction |
ISO |
17 |
77,034,737 |
77,081,406 |
RGD:6480464 |
CTD |
| G |
Akr1c2 |
aldo-keto reductase family 1, member C2 |
|
affects metabolic processing |
ISO |
17 |
77,034,737 |
77,081,406 |
RGD:6480464 |
CTD |
| G |
Crh |
corticotropin releasing hormone |
|
affects expression |
EXP |
2 |
104,764,023 |
104,765,887 |
RGD:6480464 |
CTD |
| G |
Crh |
corticotropin releasing hormone |
|
multiple interactions |
EXP |
2 |
104,764,023 |
104,765,887 |
RGD:6480464 |
CTD |
| G |
Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
|
increases hydroxylation |
ISO |
1 |
251,965,458 |
251,971,449 |
RGD:6480464 |
CTD |
| G |
Egr2 |
early growth response 2 |
|
increases expression |
EXP |
20 |
21,883,885 |
21,888,177 |
RGD:6480464 |
CTD |
| G |
Gabra4 |
gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
|
increases expression |
EXP |
14 |
39,047,461 |
39,122,531 |
RGD:6480464 |
CTD |
| G |
Gabra6 |
gamma-aminobutyric acid (GABA) A receptor, alpha 6 |
|
increases response to substance |
ISO |
10 |
27,474,071 |
27,489,074 |
RGD:6480464 |
CTD |
| G |
Gabrd |
gamma-aminobutyric acid (GABA) A receptor, delta |
|
decreases expression |
EXP |
5 |
172,203,064 |
172,214,960 |
RGD:6480464 |
CTD |
| G |
Gabre |
gamma-aminobutyric acid (GABA) A receptor, epsilon |
|
decreases response to substance |
EXP |
X |
158,335,158 |
158,353,615 |
RGD:6480464 |
CTD |
| G |
Gsk3b |
glycogen synthase kinase 3 beta |
|
decreases expression |
EXP |
11 |
64,284,731 |
64,428,698 |
RGD:6480464 |
CTD |
| G |
Mag |
myelin-associated glycoprotein |
|
increases expression |
EXP |
1 |
85,954,511 |
85,970,832 |
RGD:6480464 |
CTD |
| G |
Mapk1 |
mitogen activated protein kinase 1 |
|
multiple interactions |
ISO |
11 |
85,968,732 |
86,030,387 |
RGD:6480464 |
CTD |
| G |
Mapt |
microtubule-associated protein tau |
|
increases phosphorylation |
EXP |
10 |
93,411,098 |
93,508,762 |
RGD:6480464 |
CTD |
| G |
Mapt |
microtubule-associated protein tau |
|
decreases expression |
EXP |
10 |
93,411,098 |
93,508,762 |
RGD:6480464 |
CTD |
| G |
Mpz |
myelin protein zero |
|
increases expression |
EXP |
13 |
87,040,479 |
87,045,378 |
RGD:6480464 |
CTD |
| G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
|
multiple interactions |
ISO |
18 |
32,371,496 |
32,459,145 |
RGD:6480464 |
CTD |
| G |
Pmp22 |
peripheral myelin protein 22 |
|
increases expression |
EXP |
10 |
49,305,835 |
49,335,864 |
RGD:6480464 |
CTD |
| G |
Prkca |
protein kinase C, alpha |
|
decreases expression |
ISO |
10 |
97,367,196 |
97,638,910 |
RGD:6480464 |
CTD |
Term paths to the root
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