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Term:leukotriene C4
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Accession:CHEBI:16978 term browser browse the term
Definition:A leukotriene that has formula C30H47N3O9S.
Synonyms:exact_synonym: L-gamma-glutamyl-S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl]-L-cysteinylglycine
 related_synonym: (R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl)glycine;   5S,6R-Ltc(sub 4);   5S-hydroxy,6R-(S-glutathionyl),7E,9E,11Z,14Z-eicosatetraenoic acid;   C30H47N3O9S;   CCCCC\\C=C/C\\C=C/C=C/C=C/[C@@H](SC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O)[C@@H](O)CCCC(O)=O;   InChI=1S/C30H47N3O9S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-25(24(34)15-14-17-27(36)37)43-21-23(29(40)32-20-28(38)39)33-26(35)19-18-22(31)30(41)42/h6-7,9-13,16,22-25,34H,2-5,8,14-15,17-21,31H2,1H3,(H,32,40)(H,33,35)(H,36,37)(H,38,39)(H,41,42)/b7-6-,10-9-,12-11+,16-13+/t22-,23-,24-,25+/m0/s1;   InChIKey=GWNVDXQDILPJIG-NXOLIXFESA-N;   LTC (sub 4);   LTC4
 alt_id: CHEBI:14504;   CHEBI:25025;   CHEBI:6422
 xref_casrn: 72025-60-6
 xref: ChEMBL:555236 "ChEMBL COMPOUND";   ChemIDplus:72025-60-6 "CAS Registry Number";   KEGG COMPOUND:72025-60-6 "CAS Registry Number";   KEGG COMPOUND:C02166 "KEGG COMPOUND";   LIPID MAPS:LMFA03020003 "LIPID MAPS instance"
 xref_mesh: MESH:D017997
 cyclic_relationship: is_conjugate_acid_of CHEBI:57973

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leukotriene C4 term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Abca8b ATP-binding cassette, sub-family A (ABC1), member 8b GBrowse link affects transport ISO 11 109,794,720 109,857,130 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 GBrowse link affects transport ISO 16 14,361,653 14,474,968 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 GBrowse link multiple interactions ISO 16 14,361,653 14,474,968 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 GBrowse link multiple interactions ISO 16 14,361,653 14,474,968 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 GBrowse link multiple interactions ISO 16 14,361,653 14,474,968 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 GBrowse link affects binding ISO 16 14,361,653 14,474,968 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 GBrowse link multiple interactions ISO 16 14,361,653 14,474,968 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 GBrowse link multiple interactions ISO 16 14,361,653 14,474,968 RGD:6480464 CTD
G Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 GBrowse link multiple interactions ISO 16 14,361,653 14,474,968 RGD:6480464 CTD
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 GBrowse link affects transport ISO 19 43,856,798 43,912,708 RGD:6480464 CTD
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 GBrowse link affects transport ISO 19 43,856,798 43,912,708 RGD:6480464 CTD
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 GBrowse link increases transport ISO 19 43,856,798 43,912,708 RGD:6480464 CTD
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 GBrowse link affects transport ISO 19 43,856,798 43,912,708 RGD:6480464 CTD
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 GBrowse link affects transport ISO 19 43,856,798 43,912,708 RGD:6480464 CTD
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 GBrowse link affects transport ISO 19 43,856,798 43,912,708 RGD:6480464 CTD
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 GBrowse link affects transport ISO 19 43,856,798 43,912,708 RGD:6480464 CTD
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 GBrowse link affects transport ISO 19 43,856,798 43,912,708 RGD:6480464 CTD
G Abcc6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 GBrowse link affects transport ISO 7 53,231,750 53,285,656 RGD:6480464 CTD
G Alox5 arachidonate 5-lipoxygenase GBrowse link multiple interactions ISO 6 116,360,089 116,411,196 RGD:6480464 CTD
G Alox5 arachidonate 5-lipoxygenase GBrowse link multiple interactions ISO 6 116,360,089 116,411,196 RGD:6480464 CTD
G Alox5 arachidonate 5-lipoxygenase GBrowse link multiple interactions EXP 6 116,360,089 116,411,196 RGD:6480464 CTD
G Alox5 arachidonate 5-lipoxygenase GBrowse link multiple interactions ISO 6 116,360,089 116,411,196 RGD:6480464 CTD
G Alox5ap arachidonate 5-lipoxygenase activating protein GBrowse link multiple interactions ISO 5 150,076,634 150,099,623 RGD:6480464 CTD
G Ambp alpha 1 microglobulin/bikunin GBrowse link decreases secretion ISO 4 62,804,313 62,815,176 RGD:6480464 CTD
G Ccl12 chemokine (C-C motif) ligand 12 GBrowse link increases expression EXP 11 81,915,347 81,916,901 RGD:6480464 CTD
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link increases expression EXP 11 81,849,079 81,850,954 RGD:6480464 CTD
G Clec7a C-type lectin domain family 7, member a GBrowse link multiple interactions ISO 6 129,411,609 129,422,795 RGD:6480464 CTD
G Cxcl1 chemokine (C-X-C motif) ligand 1 GBrowse link increases expression EXP 5 91,320,271 91,322,147 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 103,771,856 103,798,801 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 103,771,856 103,798,801 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 103,771,856 103,798,801 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link affects binding ISO X 103,771,856 103,798,801 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 103,771,856 103,798,801 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 103,771,856 103,798,801 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions EXP X 103,771,856 103,798,801 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions EXP X 103,771,856 103,798,801 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 103,771,856 103,798,801 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 103,771,856 103,798,801 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link affects binding ISO X 103,771,856 103,798,801 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 103,771,856 103,798,801 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 103,771,856 103,798,801 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link multiple interactions ISO X 103,771,856 103,798,801 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link affects binding ISO X 103,771,856 103,798,801 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link affects binding ISO X 103,771,856 103,798,801 RGD:6480464 CTD
G Cysltr1 cysteinyl leukotriene receptor 1 GBrowse link affects binding ISO X 103,771,856 103,798,801 RGD:6480464 CTD
G Cysltr2 cysteinyl leukotriene receptor 2 GBrowse link multiple interactions ISO 14 73,428,935 73,448,921 RGD:6480464 CTD
G Cysltr2 cysteinyl leukotriene receptor 2 GBrowse link increases activity ISO 14 73,428,935 73,448,921 RGD:6480464 CTD
G Cysltr2 cysteinyl leukotriene receptor 2 GBrowse link multiple interactions ISO 14 73,428,935 73,448,921 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link increases expression EXP 11 16,652,206 16,813,910 RGD:6480464 CTD
G Gpr17 G protein-coupled receptor 17 GBrowse link increases activity EXP 18 32,102,653 32,109,290 RGD:6480464 CTD
G Hmox1 heme oxygenase (decycling) 1 GBrowse link multiple interactions EXP 8 77,617,517 77,624,492 RGD:6480464 CTD
G Il13 interleukin 13 GBrowse link increases expression EXP 11 53,444,825 53,448,204 RGD:6480464 CTD
G Il13 interleukin 13 GBrowse link increases abundance ISO 11 53,444,825 53,448,204 RGD:6480464 CTD
G Il13 interleukin 13 GBrowse link multiple interactions ISO 11 53,444,825 53,448,204 RGD:6480464 CTD
G Il5 interleukin 5 GBrowse link increases secretion ISO 11 53,534,296 53,538,605 RGD:6480464 CTD
G Ltc4s leukotriene C4 synthase GBrowse link affects chemical synthesis ISO 11 50,049,974 50,051,973 RGD:6480464 CTD
G Mapk1 mitogen-activated protein kinase 1 GBrowse link increases phosphorylation EXP 16 16,983,475 17,047,546 RGD:6480464 CTD
G Mapk3 mitogen-activated protein kinase 3 GBrowse link increases phosphorylation EXP 7 133,903,140 133,909,330 RGD:6480464 CTD
G Mgst1 microsomal glutathione S-transferase 1 GBrowse link multiple interactions ISO 6 138,089,058 138,105,273 RGD:6480464 CTD
G Mmp9 matrix metallopeptidase 9 GBrowse link multiple interactions EXP 2 164,773,751 164,781,346 RGD:6480464 CTD
G Mmp9 matrix metallopeptidase 9 GBrowse link increases expression EXP 2 164,773,751 164,781,346 RGD:6480464 CTD
G Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric GBrowse link increases expression ISO 7 148,974,916 149,005,040 RGD:6480464 CTD
G Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric GBrowse link multiple interactions ISO 7 148,974,916 149,005,040 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link multiple interactions EXP 11 78,734,361 78,773,626 RGD:6480464 CTD
G Pla2g5 phospholipase A2, group V GBrowse link multiple interactions ISO 4 138,355,162 138,419,384 RGD:6480464 CTD
G Pla2g5 phospholipase A2, group V GBrowse link multiple interactions EXP 4 138,355,162 138,419,384 RGD:6480464 CTD
G Ralbp1 ralA binding protein 1 GBrowse link multiple interactions ISO 17 66,197,755 66,217,171 RGD:6480464 CTD
G Ralbp1 ralA binding protein 1 GBrowse link affects transport ISO 17 66,197,755 66,217,171 RGD:6480464 CTD
G Selp selectin, platelet GBrowse link increases expression ISO 1 166,045,509 166,079,876 RGD:6480464 CTD
G Syk spleen tyrosine kinase GBrowse link multiple interactions ISO 13 52,692,251 52,744,161 RGD:6480464 CTD
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 500591
    chemical entity 500591
      atom 499508
        nonmetal atom 458033
          carbon atom 414040
            organic molecular entity 414034
              fatty acid derivative 1161
                icosanoid 1161
                  leukotriene 258
                    leukotriene C4 70
Path 2
Term Annotations click to browse term
  CHEBI ontology 500591
    subatomic particle 499508
      composite particle 499508
        hadron 499508
          baryon 499508
            nucleon 499508
              atomic nucleus 499508
                atom 499508
                  main group element atom 468781
                    p-block element atom 466276
                      carbon group element atom 417557
                        carbon atom 414040
                          organic molecular entity 414034
                            organic group 170804
                              organic divalent group 169619
                                organodiyl group 169619
                                  carbonyl group 169303
                                    carbonyl compound 169303
                                      carboxylic acid 123928
                                        monocarboxylic acid 71730
                                          fatty acid 25477
                                            unsaturated fatty acid 1504
                                              polyunsaturated fatty acid 1165
                                                icosatetraenoic acid 743
                                                  icosa-7,9,11,14-tetraenoic acid 189
                                                    leukotriene C4 70
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