ONTOLOGY REPORT - ANNOTATIONS

Term:lipoic acid
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Accession:CHEBI:16494 term browser browse the term
Definition:A heterocyclic thia fatty acid comprising pentanoic acid with a 1,2-dithiolan-3-yl group at the 5-position.
Synonyms:exact_synonym: 5-(1,2-dithiolan-3-yl)pentanoic acid
 related_synonym: 1,2-dithiolane-3-pentanoic acid;   1,2-dithiolane-3-valeric acid;   5-(1,2-dithiolan-3-yl)valeric acid;   5-(dithiolan-3-yl)valeric acid;   5-[3-(1,2-dithiolanyl)]pentanoic acid;   6,8-thioctic acid;   6,8-thiotic acid;   6-thioctic acid;   6-thiotic acid;   Acetate-replacing factor;   Biletan;   C8H14O2S2;   InChI=1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10);   InChIKey=AGBQKNBQESQNJD-UHFFFAOYSA-N;   OC(=O)CCCCC1CCSS1;   Thioctansaeure;   Thioctsaeure;   Thioktsaeure;   alpha-Liponsaeure;   alpha-lipoic acid;   liponic acid
 alt_id: CHEBI:146958;   CHEBI:25058;   CHEBI:6492
 xref_casrn: 62-46-4
 xref: Beilstein:122410 "Beilstein Registry Number";   Beilstein:81853 "Beilstein Registry Number";   ChEMBL:146958 "ChEMBL COMPOUND";   ChemIDplus:62-46-4 "CAS Registry Number";   CiteXplore:7519986 "PubMed citation";   CiteXplore:7548757 "PubMed citation";   DrugBank:DB00166 "DrugBank";   Gmelin:720915 "Gmelin Registry Number"
 xref_mesh: MESH:D008063
 xref: NIST Chemistry WebBook:62-46-4 "CAS Registry Number";   Reaxys:81853 "Reaxys Registry Number"
 cyclic_relationship: is_conjugate_acid_of CHEBI:30313

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lipoic acid term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Ache acetylcholinesterase multiple interactions EXP RGD:6480464 CTD
G Ache acetylcholinesterase multiple interactions EXP RGD:6480464 CTD
G Ache acetylcholinesterase multiple interactions ISO RGD:6480464 CTD
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link decreases phosphorylation ISO 6 137,640,482 137,657,552 RGD:6480464 CTD
G Alad aminolevulinate dehydratase GBrowse link multiple interactions EXP 5 79,505,645 79,515,983 RGD:6480464 CTD
G Alad aminolevulinate dehydratase GBrowse link multiple interactions EXP 5 79,505,645 79,515,983 RGD:6480464 CTD
G Alad aminolevulinate dehydratase GBrowse link multiple interactions EXP 5 79,505,645 79,515,983 RGD:6480464 CTD
G Alad aminolevulinate dehydratase GBrowse link multiple interactions EXP 5 79,505,645 79,515,983 RGD:6480464 CTD
G Alad aminolevulinate dehydratase GBrowse link multiple interactions EXP 5 79,505,645 79,515,983 RGD:6480464 CTD
G Alad aminolevulinate dehydratase GBrowse link multiple interactions EXP 5 79,505,645 79,515,983 RGD:6480464 CTD
G Apln apelin GBrowse link multiple interactions ISO X 134,387,285 134,396,762 RGD:6480464 CTD
G Apln apelin GBrowse link increases expression ISO X 134,387,285 134,396,762 RGD:6480464 CTD
G Apln apelin GBrowse link increases secretion ISO X 134,387,285 134,396,762 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link multiple interactions ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bche butyrylcholinesterase GBrowse link multiple interactions ISO 2 164,329,613 164,427,994 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link multiple interactions ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link decreases response to substance ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link multiple interactions ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G C1qa complement component 1, q subcomponent, A chain GBrowse link decreases expression ISO 5 155,662,333 155,665,180 RGD:6480464 CTD
G C4b complement component 4B (Chido blood group) GBrowse link decreases expression ISO 20 4,300,687 4,315,882 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link increases activity ISO 5 160,704,234 160,721,796 RGD:6480464 CTD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link multiple interactions EXP 5 160,704,234 160,721,796 RGD:6480464 CTD
G Cat catalase GBrowse link multiple interactions ISO 3 88,654,077 88,686,212 RGD:6480464 CTD
G Cat catalase GBrowse link multiple interactions EXP 3 88,654,077 88,686,212 RGD:6480464 CTD
G Cat catalase GBrowse link increases activity EXP 3 88,654,077 88,686,212 RGD:6480464 CTD
G Cat catalase GBrowse link increases activity EXP 3 88,654,077 88,686,212 RGD:6480464 CTD
G Cat catalase GBrowse link multiple interactions EXP 3 88,654,077 88,686,212 RGD:6480464 CTD
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link multiple interactions ISO 10 70,256,263 70,258,061 RGD:6480464 CTD
G Ccnd1 cyclin D1 GBrowse link multiple interactions ISO 1 205,357,235 205,366,757 RGD:6480464 CTD
G Cd36 CD36 molecule (thrombospondin receptor) GBrowse link multiple interactions ISO 4 13,471,878 13,525,620 RGD:6480464 CTD
G Cd86 CD86 molecule GBrowse link increases expression ISO 11 66,215,233 66,238,882 RGD:6480464 CTD
G Chat choline O-acetyltransferase GBrowse link multiple interactions EXP 16 7,913,026 7,965,985 RGD:6480464 CTD
G Cntf ciliary neurotrophic factor GBrowse link multiple interactions ISO 1 215,842,668 215,844,691 RGD:6480464 CTD
G Col1a1 collagen, type I, alpha 1 GBrowse link multiple interactions EXP 10 83,622,438 83,639,368 RGD:6480464 CTD
G Cryaa crystallin, alpha A multiple interactions EXP RGD:6480464 CTD
G Ctsd cathepsin D GBrowse link multiple interactions EXP 1 202,619,669 202,631,545 RGD:6480464 CTD
G Ctss cathepsin S GBrowse link decreases expression ISO 2 190,425,290 190,466,877 RGD:6480464 CTD
G Cycs cytochrome c, somatic GBrowse link multiple interactions EXP 4 78,825,878 78,827,978 RGD:6480464 CTD
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 GBrowse link multiple interactions ISO 8 61,462,207 61,468,237 RGD:6480464 CTD
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 GBrowse link multiple interactions ISO 8 61,439,062 61,447,861 RGD:6480464 CTD
G Dld dihydrolipoamide dehydrogenase GBrowse link multiple interactions EXP 6 49,185,188 49,205,894 RGD:6480464 CTD
G Drd2 dopamine receptor D2 GBrowse link multiple interactions ISO 8 52,641,160 52,707,749 RGD:6480464 CTD
G Fshb follicle stimulating hormone, beta polypeptide GBrowse link multiple interactions EXP 3 92,569,344 92,571,254 RGD:6480464 CTD
G Gclc glutamate-cysteine ligase, catalytic subunit GBrowse link increases expression ISO 8 82,724,429 82,762,848 RGD:6480464 CTD
G Gclc glutamate-cysteine ligase, catalytic subunit GBrowse link increases expression ISO 8 82,724,429 82,762,848 RGD:6480464 CTD
G Gclm glutamate cysteine ligase, modifier subunit GBrowse link increases expression ISO 2 218,895,434 218,915,491 RGD:6480464 CTD
G Gfap glial fibrillary acidic protein GBrowse link decreases expression ISO 10 92,059,881 92,068,555 RGD:6480464 CTD
G Gsk3b glycogen synthase kinase 3 beta GBrowse link increases phosphorylation ISO 11 64,284,731 64,428,698 RGD:6480464 CTD
G Gsr glutathione reductase GBrowse link multiple interactions EXP 16 62,255,562 62,298,458 RGD:6480464 CTD
G Gstm1 glutathione S-transferase mu 1 GBrowse link multiple interactions ISO 2 203,575,444 203,580,821 RGD:6480464 CTD
G Gstp1 glutathione S-transferase pi 1 GBrowse link multiple interactions EXP 1 206,627,398 206,629,866 RGD:6480464 CTD
G Gstp1 glutathione S-transferase pi 1 GBrowse link increases expression EXP 1 206,627,398 206,629,866 RGD:6480464 CTD
G Gstp1 glutathione S-transferase pi 1 GBrowse link multiple interactions EXP 1 206,627,398 206,629,866 RGD:6480464 CTD
G Gusb glucuronidase, beta GBrowse link multiple interactions EXP 12 27,744,409 27,757,755 RGD:6480464 CTD
G Hmox1 heme oxygenase (decycling) 1 GBrowse link increases expression ISO 19 13,963,139 13,969,960 RGD:6480464 CTD
G Hmox1 heme oxygenase (decycling) 1 GBrowse link multiple interactions ISO 19 13,963,139 13,969,960 RGD:6480464 CTD
G Hmox1 heme oxygenase (decycling) 1 GBrowse link multiple interactions ISO 19 13,963,139 13,969,960 RGD:6480464 CTD
G Il10 interleukin 10 GBrowse link multiple interactions EXP 13 43,953,900 43,957,766 RGD:6480464 CTD
G Il2 interleukin 2 GBrowse link multiple interactions EXP 2 123,655,005 123,659,709 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link multiple interactions ISO 4 456,799 461,376 RGD:6480464 CTD
G Ins1 insulin 1 GBrowse link multiple interactions EXP 1 258,001,134 258,001,688 RGD:6480464 CTD
G Ins2 insulin 2 GBrowse link multiple interactions ISO 1 202,935,548 202,936,379 RGD:6480464 CTD
G Jun jun proto-oncogene GBrowse link increases activity EXP 5 115,358,166 115,361,259 RGD:6480464 CTD
G Jun jun proto-oncogene GBrowse link increases expression EXP 5 115,358,166 115,361,259 RGD:6480464 CTD
G Jun jun proto-oncogene GBrowse link multiple interactions EXP 5 115,358,166 115,361,259 RGD:6480464 CTD
G Keap1 Kelch-like ECH-associated protein 1 GBrowse link increases expression ISO 8 20,259,178 20,266,351 RGD:6480464 CTD
G Ldhc lactate dehydrogenase C GBrowse link multiple interactions EXP 1 97,418,622 97,435,275 RGD:6480464 CTD
G Lep leptin GBrowse link decreases secretion ISO 4 55,943,837 55,945,938 RGD:6480464 CTD
G Lep leptin GBrowse link decreases expression ISO 4 55,943,837 55,945,938 RGD:6480464 CTD
G Lep leptin GBrowse link decreases expression EXP 4 55,943,837 55,945,938 RGD:6480464 CTD
G Lhb luteinizing hormone beta GBrowse link multiple interactions EXP 1 95,892,999 95,893,988 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link affects activity EXP 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions EXP 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions EXP 1 185,935,044 185,941,245 RGD:6480464 CTD
G Msr1 macrophage scavenger receptor 1 GBrowse link multiple interactions ISO 16 56,278,223 56,345,472 RGD:6480464 CTD
G Mt1a metallothionein 1a GBrowse link multiple interactions ISO 19 11,261,631 11,262,647 RGD:6480464 CTD
G Mvd mevalonate (diphospho) decarboxylase GBrowse link multiple interactions ISO 19 52,722,306 52,732,312 RGD:6480464 CTD
G Myc myelocytomatosis oncogene GBrowse link multiple interactions ISO 7 98,953,142 98,958,060 RGD:6480464 CTD
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 GBrowse link multiple interactions ISO 3 58,366,693 58,394,116 RGD:6480464 CTD
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 GBrowse link multiple interactions ISO 3 58,366,693 58,394,116 RGD:6480464 CTD
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 GBrowse link multiple interactions ISO 3 58,366,693 58,394,116 RGD:6480464 CTD
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 GBrowse link decreases expression ISO 3 58,366,693 58,394,116 RGD:6480464 CTD
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 GBrowse link multiple interactions EXP 3 58,366,693 58,394,116 RGD:6480464 CTD
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 GBrowse link increases expression EXP 3 58,366,693 58,394,116 RGD:6480464 CTD
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 GBrowse link increases activity EXP 3 58,366,693 58,394,116 RGD:6480464 CTD
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 GBrowse link multiple interactions ISO 2 233,091,013 233,187,501 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link multiple interactions ISO 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link increases activity ISO 19 37,251,147 37,266,040 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link increases expression ISO 19 37,251,147 37,266,040 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link increases activity EXP 19 37,251,147 37,266,040 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link increases expression EXP 19 37,251,147 37,266,040 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link increases expression ISO 19 37,251,147 37,266,040 RGD:6480464 CTD
G Pah phenylalanine hydroxylase GBrowse link decreases expression ISO 7 24,175,898 24,243,592 RGD:6480464 CTD
G Pcna proliferating cell nuclear antigen GBrowse link multiple interactions EXP 3 120,008,715 120,012,589 RGD:6480464 CTD
G Por P450 (cytochrome) oxidoreductase GBrowse link multiple interactions ISO 12 22,078,629 22,097,301 RGD:6480464 CTD
G Por P450 (cytochrome) oxidoreductase GBrowse link decreases activity ISO 12 22,078,629 22,097,301 RGD:6480464 CTD
G Potef POTE ankyrin domain family, member F GBrowse link multiple interactions EXP 18 24,420,779 24,422,284 RGD:6480464 CTD
G Ppargc1a peroxisome proliferator-activated receptor gamma, coactivator 1 alpha GBrowse link multiple interactions ISO 14 64,278,115 64,370,912 RGD:6480464 CTD
G Ppargc1a peroxisome proliferator-activated receptor gamma, coactivator 1 alpha GBrowse link increases expression ISO 14 64,278,115 64,370,912 RGD:6480464 CTD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link multiple interactions EXP 13 64,427,288 64,432,978 RGD:6480464 CTD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link multiple interactions ISO 1 208,262,669 208,273,148 RGD:6480464 CTD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link decreases phosphorylation ISO 1 208,262,669 208,273,148 RGD:6480464 CTD
G Slc5a6 solute carrier family 5 (sodium-dependent vitamin transporter), member 6 GBrowse link increases transport ISO 6 25,301,630 25,312,901 RGD:6480464 CTD
G Slc5a6 solute carrier family 5 (sodium-dependent vitamin transporter), member 6 GBrowse link multiple interactions ISO 6 25,301,630 25,312,901 RGD:6480464 CTD
G Slc5a6 solute carrier family 5 (sodium-dependent vitamin transporter), member 6 GBrowse link multiple interactions EXP 6 25,301,630 25,312,901 RGD:6480464 CTD
G Snca synuclein, alpha (non A4 component of amyloid precursor) GBrowse link multiple interactions ISO 4 89,613,731 89,722,807 RGD:6480464 CTD
G Sod1 superoxide dismutase 1, soluble GBrowse link multiple interactions EXP 11 29,810,766 29,816,342 RGD:6480464 CTD
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link multiple interactions EXP 1 41,862,997 41,870,327 RGD:6480464 CTD
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link multiple interactions EXP 1 41,862,997 41,870,327 RGD:6480464 CTD
G Sp1 Sp1 transcription factor GBrowse link multiple interactions ISO 7 141,164,180 141,194,509 RGD:6480464 CTD
G Stat1 signal transducer and activator of transcription 1 GBrowse link multiple interactions ISO 9 46,455,635 46,497,560 RGD:6480464 CTD
G Stat3 signal transducer and activator of transcription 3 (acute-phase response factor) GBrowse link multiple interactions ISO 10 89,821,078 89,872,970 RGD:6480464 CTD
G Tgfb1 transforming growth factor, beta 1 GBrowse link multiple interactions EXP 1 80,894,705 80,911,020 RGD:6480464 CTD
G Tgfb1 transforming growth factor, beta 1 GBrowse link multiple interactions EXP 1 80,894,705 80,911,020 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnni3 troponin I type 3 (cardiac) GBrowse link multiple interactions EXP 1 68,028,198 68,031,882 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link multiple interactions EXP 10 56,399,721 56,411,150 RGD:6480464 CTD
G Txnrd1 thioredoxin reductase 1 GBrowse link increases reduction ISO 7 23,055,544 23,093,815 RGD:6480464 CTD
G Txnrd1 thioredoxin reductase 1 GBrowse link multiple interactions EXP 7 23,055,544 23,093,815 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link multiple interactions EXP 9 10,520,730 10,536,071 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link multiple interactions ISO 9 10,520,730 10,536,071 RGD:6480464 CTD
(R)-lipoic acid term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Ache acetylcholinesterase multiple interactions EXP RGD:6480464 CTD
G Ache acetylcholinesterase multiple interactions EXP RGD:6480464 CTD
G Ache acetylcholinesterase multiple interactions ISO RGD:6480464 CTD
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link decreases phosphorylation ISO 6 137,640,482 137,657,552 RGD:6480464 CTD
G Alad aminolevulinate dehydratase GBrowse link multiple interactions EXP 5 79,505,645 79,515,983 RGD:6480464 CTD
G Alad aminolevulinate dehydratase GBrowse link multiple interactions EXP 5 79,505,645 79,515,983 RGD:6480464 CTD
G Alad aminolevulinate dehydratase GBrowse link multiple interactions EXP 5 79,505,645 79,515,983 RGD:6480464 CTD
G Alad aminolevulinate dehydratase GBrowse link multiple interactions EXP 5 79,505,645 79,515,983 RGD:6480464 CTD
G Alad aminolevulinate dehydratase GBrowse link multiple interactions EXP 5 79,505,645 79,515,983 RGD:6480464 CTD
G Alad aminolevulinate dehydratase GBrowse link multiple interactions EXP 5 79,505,645 79,515,983 RGD:6480464 CTD
G Apln apelin GBrowse link multiple interactions ISO X 134,387,285 134,396,762 RGD:6480464 CTD
G Apln apelin GBrowse link increases expression ISO X 134,387,285 134,396,762 RGD:6480464 CTD
G Apln apelin GBrowse link increases secretion ISO X 134,387,285 134,396,762 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link multiple interactions ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bche butyrylcholinesterase GBrowse link multiple interactions ISO 2 164,329,613 164,427,994 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link multiple interactions ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link decreases response to substance ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link multiple interactions ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G C1qa complement component 1, q subcomponent, A chain GBrowse link decreases expression ISO 5 155,662,333 155,665,180 RGD:6480464 CTD
G C4b complement component 4B (Chido blood group) GBrowse link decreases expression ISO 20 4,300,687 4,315,882 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link increases activity ISO 5 160,704,234 160,721,796 RGD:6480464 CTD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link multiple interactions EXP 5 160,704,234 160,721,796 RGD:6480464 CTD
G Cat catalase GBrowse link multiple interactions ISO 3 88,654,077 88,686,212 RGD:6480464 CTD
G Cat catalase GBrowse link multiple interactions EXP 3 88,654,077 88,686,212 RGD:6480464 CTD
G Cat catalase GBrowse link increases activity EXP 3 88,654,077 88,686,212 RGD:6480464 CTD
G Cat catalase GBrowse link increases activity EXP 3 88,654,077 88,686,212 RGD:6480464 CTD
G Cat catalase GBrowse link multiple interactions EXP 3 88,654,077 88,686,212 RGD:6480464 CTD
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link multiple interactions ISO 10 70,256,263 70,258,061 RGD:6480464 CTD
G Ccnd1 cyclin D1 GBrowse link multiple interactions ISO 1 205,357,235 205,366,757 RGD:6480464 CTD
G Cd36 CD36 molecule (thrombospondin receptor) GBrowse link multiple interactions ISO 4 13,471,878 13,525,620 RGD:6480464 CTD
G Cd86 CD86 molecule GBrowse link increases expression ISO 11 66,215,233 66,238,882 RGD:6480464 CTD
G Chat choline O-acetyltransferase GBrowse link multiple interactions EXP 16 7,913,026 7,965,985 RGD:6480464 CTD
G Cntf ciliary neurotrophic factor GBrowse link multiple interactions ISO 1 215,842,668 215,844,691 RGD:6480464 CTD
G Col1a1 collagen, type I, alpha 1 GBrowse link multiple interactions EXP 10 83,622,438 83,639,368 RGD:6480464 CTD
G Cryaa crystallin, alpha A multiple interactions EXP RGD:6480464 CTD
G Ctsd cathepsin D GBrowse link multiple interactions EXP 1 202,619,669 202,631,545 RGD:6480464 CTD
G Ctss cathepsin S GBrowse link decreases expression ISO 2 190,425,290 190,466,877 RGD:6480464 CTD
G Cycs cytochrome c, somatic GBrowse link multiple interactions EXP 4 78,825,878 78,827,978 RGD:6480464 CTD
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 GBrowse link multiple interactions ISO 8 61,462,207 61,468,237 RGD:6480464 CTD
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 GBrowse link multiple interactions ISO 8 61,439,062 61,447,861 RGD:6480464 CTD
G Dld dihydrolipoamide dehydrogenase GBrowse link multiple interactions EXP 6 49,185,188 49,205,894 RGD:6480464 CTD
G Drd2 dopamine receptor D2 GBrowse link multiple interactions ISO 8 52,641,160 52,707,749 RGD:6480464 CTD
G Fshb follicle stimulating hormone, beta polypeptide GBrowse link multiple interactions EXP 3 92,569,344 92,571,254 RGD:6480464 CTD
G Gclc glutamate-cysteine ligase, catalytic subunit GBrowse link increases expression ISO 8 82,724,429 82,762,848 RGD:6480464 CTD
G Gclc glutamate-cysteine ligase, catalytic subunit GBrowse link increases expression ISO 8 82,724,429 82,762,848 RGD:6480464 CTD
G Gclm glutamate cysteine ligase, modifier subunit GBrowse link increases expression ISO 2 218,895,434 218,915,491 RGD:6480464 CTD
G Gfap glial fibrillary acidic protein GBrowse link decreases expression ISO 10 92,059,881 92,068,555 RGD:6480464 CTD
G Gsk3b glycogen synthase kinase 3 beta GBrowse link increases phosphorylation ISO 11 64,284,731 64,428,698 RGD:6480464 CTD
G Gsr glutathione reductase GBrowse link multiple interactions EXP 16 62,255,562 62,298,458 RGD:6480464 CTD
G Gstm1 glutathione S-transferase mu 1 GBrowse link multiple interactions ISO 2 203,575,444 203,580,821 RGD:6480464 CTD
G Gstp1 glutathione S-transferase pi 1 GBrowse link multiple interactions EXP 1 206,627,398 206,629,866 RGD:6480464 CTD
G Gstp1 glutathione S-transferase pi 1 GBrowse link increases expression EXP 1 206,627,398 206,629,866 RGD:6480464 CTD
G Gstp1 glutathione S-transferase pi 1 GBrowse link multiple interactions EXP 1 206,627,398 206,629,866 RGD:6480464 CTD
G Gusb glucuronidase, beta GBrowse link multiple interactions EXP 12 27,744,409 27,757,755 RGD:6480464 CTD
G Hmox1 heme oxygenase (decycling) 1 GBrowse link increases expression ISO 19 13,963,139 13,969,960 RGD:6480464 CTD
G Hmox1 heme oxygenase (decycling) 1 GBrowse link multiple interactions ISO 19 13,963,139 13,969,960 RGD:6480464 CTD
G Hmox1 heme oxygenase (decycling) 1 GBrowse link multiple interactions ISO 19 13,963,139 13,969,960 RGD:6480464 CTD
G Il10 interleukin 10 GBrowse link multiple interactions EXP 13 43,953,900 43,957,766 RGD:6480464 CTD
G Il2 interleukin 2 GBrowse link multiple interactions EXP 2 123,655,005 123,659,709 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link multiple interactions ISO 4 456,799 461,376 RGD:6480464 CTD
G Ins1 insulin 1 GBrowse link multiple interactions EXP 1 258,001,134 258,001,688 RGD:6480464 CTD
G Ins2 insulin 2 GBrowse link multiple interactions ISO 1 202,935,548 202,936,379 RGD:6480464 CTD
G Jun jun proto-oncogene GBrowse link increases expression EXP 5 115,358,166 115,361,259 RGD:6480464 CTD
G Jun jun proto-oncogene GBrowse link multiple interactions EXP 5 115,358,166 115,361,259 RGD:6480464 CTD
G Jun jun proto-oncogene GBrowse link increases activity EXP 5 115,358,166 115,361,259 RGD:6480464 CTD
G Keap1 Kelch-like ECH-associated protein 1 GBrowse link increases expression ISO 8 20,259,178 20,266,351 RGD:6480464 CTD
G Ldhc lactate dehydrogenase C GBrowse link multiple interactions EXP 1 97,418,622 97,435,275 RGD:6480464 CTD
G Lep leptin GBrowse link decreases secretion ISO 4 55,943,837 55,945,938 RGD:6480464 CTD
G Lep leptin GBrowse link decreases expression ISO 4 55,943,837 55,945,938 RGD:6480464 CTD
G Lep leptin GBrowse link decreases expression EXP 4 55,943,837 55,945,938 RGD:6480464 CTD
G Lhb luteinizing hormone beta GBrowse link multiple interactions EXP 1 95,892,999 95,893,988 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link affects activity EXP 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions EXP 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions EXP 1 185,935,044 185,941,245 RGD:6480464 CTD
G Msr1 macrophage scavenger receptor 1 GBrowse link multiple interactions ISO 16 56,278,223 56,345,472 RGD:6480464 CTD
G Mt1a metallothionein 1a GBrowse link multiple interactions ISO 19 11,261,631 11,262,647 RGD:6480464 CTD
G Mvd mevalonate (diphospho) decarboxylase GBrowse link multiple interactions ISO 19 52,722,306 52,732,312 RGD:6480464 CTD
G Myc myelocytomatosis oncogene GBrowse link multiple interactions ISO 7 98,953,142 98,958,060 RGD:6480464 CTD
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 GBrowse link multiple interactions ISO 3 58,366,693 58,394,116 RGD:6480464 CTD
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 GBrowse link multiple interactions ISO 3 58,366,693 58,394,116 RGD:6480464 CTD
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 GBrowse link multiple interactions ISO 3 58,366,693 58,394,116 RGD:6480464 CTD
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 GBrowse link decreases expression ISO 3 58,366,693 58,394,116 RGD:6480464 CTD
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 GBrowse link multiple interactions EXP 3 58,366,693 58,394,116 RGD:6480464 CTD
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 GBrowse link increases activity EXP 3 58,366,693 58,394,116 RGD:6480464 CTD
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 GBrowse link increases expression EXP 3 58,366,693 58,394,116 RGD:6480464 CTD
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 GBrowse link multiple interactions ISO 2 233,091,013 233,187,501 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link multiple interactions ISO 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link increases activity ISO 19 37,251,147 37,266,040 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link increases expression ISO 19 37,251,147 37,266,040 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link increases activity EXP 19 37,251,147 37,266,040 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link increases expression EXP 19 37,251,147 37,266,040 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link increases expression ISO 19 37,251,147 37,266,040 RGD:6480464 CTD
G Pah phenylalanine hydroxylase GBrowse link decreases expression ISO 7 24,175,898 24,243,592 RGD:6480464 CTD
G Pcna proliferating cell nuclear antigen GBrowse link multiple interactions EXP 3 120,008,715 120,012,589 RGD:6480464 CTD
G Por P450 (cytochrome) oxidoreductase GBrowse link multiple interactions ISO 12 22,078,629 22,097,301 RGD:6480464 CTD
G Por P450 (cytochrome) oxidoreductase GBrowse link decreases activity ISO 12 22,078,629 22,097,301 RGD:6480464 CTD
G Potef POTE ankyrin domain family, member F GBrowse link multiple interactions EXP 18 24,420,779 24,422,284 RGD:6480464 CTD
G Ppargc1a peroxisome proliferator-activated receptor gamma, coactivator 1 alpha GBrowse link multiple interactions ISO 14 64,278,115 64,370,912 RGD:6480464 CTD
G Ppargc1a peroxisome proliferator-activated receptor gamma, coactivator 1 alpha GBrowse link increases expression ISO 14 64,278,115 64,370,912 RGD:6480464 CTD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link multiple interactions EXP 13 64,427,288 64,432,978 RGD:6480464 CTD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link multiple interactions ISO 1 208,262,669 208,273,148 RGD:6480464 CTD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link decreases phosphorylation ISO 1 208,262,669 208,273,148 RGD:6480464 CTD
G Slc5a6 solute carrier family 5 (sodium-dependent vitamin transporter), member 6 GBrowse link increases transport ISO 6 25,301,630 25,312,901 RGD:6480464 CTD
G Slc5a6 solute carrier family 5 (sodium-dependent vitamin transporter), member 6 GBrowse link multiple interactions ISO 6 25,301,630 25,312,901 RGD:6480464 CTD
G Slc5a6 solute carrier family 5 (sodium-dependent vitamin transporter), member 6 GBrowse link multiple interactions EXP 6 25,301,630 25,312,901 RGD:6480464 CTD
G Snca synuclein, alpha (non A4 component of amyloid precursor) GBrowse link multiple interactions ISO 4 89,613,731 89,722,807 RGD:6480464 CTD
G Sod1 superoxide dismutase 1, soluble GBrowse link multiple interactions EXP 11 29,810,766 29,816,342 RGD:6480464 CTD
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link multiple interactions EXP 1 41,862,997 41,870,327 RGD:6480464 CTD
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link multiple interactions EXP 1 41,862,997 41,870,327 RGD:6480464 CTD
G Sp1 Sp1 transcription factor GBrowse link multiple interactions ISO 7 141,164,180 141,194,509 RGD:6480464 CTD
G Stat1 signal transducer and activator of transcription 1 GBrowse link multiple interactions ISO 9 46,455,635 46,497,560 RGD:6480464 CTD
G Stat3 signal transducer and activator of transcription 3 (acute-phase response factor) GBrowse link multiple interactions ISO 10 89,821,078 89,872,970 RGD:6480464 CTD
G Tgfb1 transforming growth factor, beta 1 GBrowse link multiple interactions EXP 1 80,894,705 80,911,020 RGD:6480464 CTD
G Tgfb1 transforming growth factor, beta 1 GBrowse link multiple interactions EXP 1 80,894,705 80,911,020 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnni3 troponin I type 3 (cardiac) GBrowse link multiple interactions EXP 1 68,028,198 68,031,882 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link multiple interactions EXP 10 56,399,721 56,411,150 RGD:6480464 CTD
G Txnrd1 thioredoxin reductase 1 GBrowse link increases reduction ISO 7 23,055,544 23,093,815 RGD:6480464 CTD
G Txnrd1 thioredoxin reductase 1 GBrowse link multiple interactions EXP 7 23,055,544 23,093,815 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link multiple interactions EXP 9 10,520,730 10,536,071 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link multiple interactions ISO 9 10,520,730 10,536,071 RGD:6480464 CTD
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 492574
    chemical entity 492574
      molecular entity 475835
        polyatomic entity 442085
          molecule 364791
            cyclic compound 300260
              heterocyclic compound 154278
                heterocyclic fatty acid 235
                  lipoic acid 234
                    (R)-lipoic acid + 117
                    (S)-lipoic acid + 0
                    lipoyl group + 0
                    lipoyl-AMP 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 492574
    subatomic particle 491537
      composite particle 491537
        hadron 491537
          baryon 491537
            nucleon 491537
              atomic nucleus 491537
                atom 491537
                  main group element atom 461203
                    p-block element atom 458699
                      carbon group element atom 410677
                        carbon atom 407233
                          organic molecular entity 407226
                            organic group 167766
                              organic divalent group 166601
                                organodiyl group 166601
                                  carbonyl group 166291
                                    carbonyl compound 166291
                                      carboxylic acid 121484
                                        monocarboxylic acid 70508
                                          fatty acid 25073
                                            saturated fatty acid 21707
                                              straight-chain saturated fatty acid 14378
                                                caprylic acid 2327
                                                  lipoic acid 234
                                                    (R)-lipoic acid + 117
                                                    (S)-lipoic acid + 0
                                                    lipoyl group + 0
                                                    lipoyl-AMP 0
paths to the root

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