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Term:cholic acid
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Accession:CHEBI:16359 term browser browse the term
Definition:A bile acid that is 5beta-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12.
Synonyms:exact_synonym: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oic acid
 related_synonym: (3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxycholan-24-oic acid;   (3alpha,5beta,7alpha,8alpha,12alpha,14beta,17alpha)-3,7,12-trihydroxycholan-24-oic acid;   3alpha,7alpha,12alpha-Trihydroxy-5beta-cholanic acid;   C24H40O5;   Cholsaeure;   InChI=1S/C24H40O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-/m1/s1;   InChIKey=BHQCQFFYRZLCQQ-OELDTZBJSA-N;   [H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]1([H])C[C@H](O)[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])[C@H](O)C2)[C@H](C)CCC(O)=O
 alt_id: CHEBI:1694;   CHEBI:20223;   CHEBI:23210;   CHEBI:41494
 xref_casrn: 81-25-4
 xref: ChEMBL:443964 "ChEMBL COMPOUND";   ChemIDplus:2822009 "Beilstein Registry Number";   ChemIDplus:81-25-4 "CAS Registry Number";   CiteXplore:22770225 "PubMed citation";   DrugBank:DB02659 "DrugBank";   HMDB:HMDB00619 "HMDB";   KEGG COMPOUND:81-25-4 "CAS Registry Number";   KEGG COMPOUND:C00695 "KEGG COMPOUND";   LIPID MAPS:LMST04010001 "LIPID MAPS instance"
 xref_mesh: MESH:D019826
 xref: MetaCyc:CHOLATE "MetaCyc";   NIST Chemistry WebBook:81-25-4 "CAS Registry Number";   PDBeChem:CHD "PDBeChem";   Reaxys:2822009 "Reaxys Registry Number";   Wikipedia:Cholic_Acid "Wikipedia"
 cyclic_relationship: is_conjugate_acid_of CHEBI:29747

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cholic acid term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Abca1 ATP-binding cassette, subfamily A (ABC1), member 1 GBrowse link increases expression ISO 5 70,493,357 70,583,729 RGD:6480464 CTD
G Abca1 ATP-binding cassette, subfamily A (ABC1), member 1 GBrowse link multiple interactions EXP 5 70,493,357 70,583,729 RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 increases expression ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 increases expression ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 increases expression ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 increases expression EXP RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 multiple interactions EXP RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 increases expression ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 increases expression ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 increases expression ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 increases expression ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 increases expression ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 increases expression ISO RGD:6480464 CTD
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B GBrowse link increases expression ISO 4 21,829,489 21,912,239 RGD:6480464 CTD
G Abcb4 ATP-binding cassette, subfamily B (MDR/TAP), member 4 GBrowse link affects secretion ISO 4 21,946,274 22,004,328 RGD:6480464 CTD
G Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 increases expression ISO RGD:6480464 CTD
G Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 increases expression ISO RGD:6480464 CTD
G Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 increases expression ISO RGD:6480464 CTD
G Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 increases expression ISO RGD:6480464 CTD
G Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 increases expression ISO RGD:6480464 CTD
G Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 increases expression ISO RGD:6480464 CTD
G Abcc3 ATP-binding cassette, subfamily C (CFTR/MRP), member 3 GBrowse link increases expression ISO 10 82,986,552 83,030,799 RGD:6480464 CTD
G Cat catalase GBrowse link multiple interactions EXP 3 88,654,077 88,686,212 RGD:6480464 CTD
G Chek1 checkpoint kinase 1 GBrowse link increases expression ISO 8 37,954,322 37,974,748 RGD:6480464 CTD
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 GBrowse link increases expression ISO 1 81,944,896 81,953,007 RGD:6480464 CTD
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 GBrowse link increases expression ISO 1 81,266,828 81,290,471 RGD:6480464 CTD
G Cyp2b13 cytochrome P450, family 2, subfamily b, polypeptide 13 GBrowse link increases expression ISO 1 81,408,436 81,582,029 RGD:6480464 CTD
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 GBrowse link increases expression ISO 1 81,345,425 81,359,415 RGD:6480464 CTD
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO RGD:6480464 CTD
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 GBrowse link increases expression ISO 5 135,901,653 135,915,754 RGD:6480464 CTD
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 GBrowse link increases expression ISO 5 135,876,140 135,893,753 RGD:6480464 CTD
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 GBrowse link decreases expression ISO 5 19,707,159 19,716,856 RGD:6480464 CTD
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 GBrowse link decreases expression ISO 5 19,707,159 19,716,856 RGD:6480464 CTD
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 GBrowse link multiple interactions EXP 5 19,707,159 19,716,856 RGD:6480464 CTD
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 GBrowse link decreases expression ISO 5 19,707,159 19,716,856 RGD:6480464 CTD
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 GBrowse link decreases expression ISO 5 19,707,159 19,716,856 RGD:6480464 CTD
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 GBrowse link decreases expression ISO 5 19,707,159 19,716,856 RGD:6480464 CTD
G Cyp7b1 cytochrome P450, family 7, subfamily b, polypeptide 1 GBrowse link decreases expression ISO 2 103,102,679 103,271,273 RGD:6480464 CTD
G Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 GBrowse link decreases expression ISO 8 127,018,908 127,020,878 RGD:6480464 CTD
G Fmo3 flavin containing monooxygenase 3 GBrowse link increases expression ISO 13 78,659,513 78,678,524 RGD:6480464 CTD
G Fmo4 flavin containing monooxygenase 4 GBrowse link increases expression ISO 13 78,476,211 78,494,458 RGD:6480464 CTD
G Fosl1 fos-like antigen 1 GBrowse link increases expression ISO 1 208,090,612 208,099,118 RGD:6480464 CTD
G Gsta2 glutathione S-transferase alpha 2 GBrowse link increases expression ISO 8 83,299,249 83,312,958 RGD:6480464 CTD
G Gsta4 glutathione S-transferase alpha 4 GBrowse link increases expression ISO 8 83,165,139 83,183,055 RGD:6480464 CTD
G Gstm2 glutathione S-transferase mu 2 GBrowse link increases expression ISO 2 203,549,022 203,553,380 RGD:6480464 CTD
G Gstm3 glutathione S-transferase mu 3 GBrowse link increases expression ISO 2 203,532,363 203,537,135 RGD:6480464 CTD
G Gstt2 glutathione S-transferase, theta 2 GBrowse link increases expression ISO 20 13,221,696 13,225,367 RGD:6480464 CTD
G Hells helicase, lymphoid specific GBrowse link increases expression ISO 1 243,246,843 243,262,459 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link multiple interactions ISO 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il1rl1 interleukin 1 receptor-like 1 GBrowse link increases expression ISO 9 39,577,879 39,624,781 RGD:6480464 CTD
G Lpl lipoprotein lipase GBrowse link multiple interactions EXP 16 22,533,105 22,556,905 RGD:6480464 CTD
G Mcm3 minichromosome maintenance complex component 3 GBrowse link increases expression ISO 9 19,536,922 19,554,871 RGD:6480464 CTD
G Mgst3 microsomal glutathione S-transferase 3 GBrowse link increases expression ISO 13 83,038,049 83,058,802 RGD:6480464 CTD
G Mt1a metallothionein 1a GBrowse link increases expression ISO 19 11,261,631 11,262,647 RGD:6480464 CTD
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 GBrowse link increases expression ISO 5 151,524,685 151,528,000 RGD:6480464 CTD
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 GBrowse link multiple interactions ISO 5 151,524,685 151,528,000 RGD:6480464 CTD
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 GBrowse link multiple interactions EXP 5 151,524,685 151,528,000 RGD:6480464 CTD
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 GBrowse link increases expression ISO 5 151,524,685 151,528,000 RGD:6480464 CTD
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 GBrowse link increases expression EXP 5 151,524,685 151,528,000 RGD:6480464 CTD
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 GBrowse link increases expression ISO 5 151,524,685 151,528,000 RGD:6480464 CTD
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 GBrowse link increases expression ISO 5 151,524,685 151,528,000 RGD:6480464 CTD
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 GBrowse link increases expression ISO 5 151,524,685 151,528,000 RGD:6480464 CTD
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 GBrowse link increases expression ISO 5 151,524,685 151,528,000 RGD:6480464 CTD
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 GBrowse link multiple interactions EXP 3 75,542,211 75,550,793 RGD:6480464 CTD
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 GBrowse link affects binding ISO 7 26,189,759 26,307,061 RGD:6480464 CTD
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 GBrowse link multiple interactions EXP 7 26,189,759 26,307,061 RGD:6480464 CTD
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 GBrowse link increases activity ISO 7 26,189,759 26,307,061 RGD:6480464 CTD
G Orm1 orosomucoid 1 GBrowse link increases expression ISO 5 80,325,042 80,328,194 RGD:6480464 CTD
G Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 GBrowse link increases expression ISO 1 236,592,414 236,677,379 RGD:6480464 CTD
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 GBrowse link increases expression ISO 10 55,227,872 55,248,301 RGD:6480464 CTD
G Pon1 paraoxonase 1 GBrowse link decreases expression ISO 4 29,936,314 29,964,821 RGD:6480464 CTD
G Por P450 (cytochrome) oxidoreductase GBrowse link increases expression ISO 12 22,078,629 22,097,301 RGD:6480464 CTD
G Rif1 RAP1 interacting factor homolog (yeast) GBrowse link increases expression ISO 3 33,574,934 33,624,794 RGD:6480464 CTD
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 GBrowse link decreases expression ISO 6 104,735,839 104,749,464 RGD:6480464 CTD
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 GBrowse link decreases expression ISO 6 104,735,839 104,749,464 RGD:6480464 CTD
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 GBrowse link decreases expression ISO 6 104,735,839 104,749,464 RGD:6480464 CTD
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 GBrowse link decreases expression ISO 6 104,735,839 104,749,464 RGD:6480464 CTD
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 GBrowse link decreases expression ISO 6 104,735,839 104,749,464 RGD:6480464 CTD
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 GBrowse link decreases expression ISO 6 104,735,839 104,749,464 RGD:6480464 CTD
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 GBrowse link increases expression ISO 5 139,690,801 139,719,021 RGD:6480464 CTD
G Slco1a1 solute carrier organic anion transporter family, member 1a1 decreases expression ISO RGD:6480464 CTD
G Slco1a1 solute carrier organic anion transporter family, member 1a1 decreases expression ISO RGD:6480464 CTD
G Slco1a1 solute carrier organic anion transporter family, member 1a1 decreases expression ISO RGD:6480464 CTD
G Slco1a4 solute carrier organic anion transporter family, member 1a4 increases expression ISO RGD:6480464 CTD
G Slco1b3 solute carrier organic anion transporter family, member 1b3 GBrowse link increases uptake ISO 4 179,045,586 179,118,680 RGD:6480464 CTD
G Stmn1 stathmin 1 GBrowse link increases expression ISO 5 153,226,420 153,232,084 RGD:6480464 CTD
G Sult1a1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 GBrowse link increases expression ISO 1 185,829,205 185,832,725 RGD:6480464 CTD
G Sult1d1 sulfotransferase family 1D, member 1 GBrowse link increases expression ISO 14 21,983,705 22,002,744 RGD:6480464 CTD
G Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 GBrowse link increases expression ISO 1 75,632,632 75,708,022 RGD:6480464 CTD
G Tfrc transferrin receptor GBrowse link increases expression ISO 11 69,976,258 69,998,098 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link increases expression ISO 9 10,520,730 10,536,071 RGD:6480464 CTD
glycocholic acid term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 affects transport EXP RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 affects transport ISO RGD:6480464 CTD
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 GBrowse link increases activity ISO 7 26,189,759 26,307,061 RGD:6480464 CTD
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 GBrowse link affects transport EXP 6 104,735,839 104,749,464 RGD:6480464 CTD
hyodeoxycholic acid term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Ugt2b7 UDP glucuronosyltransferase 2 family, polypeptide B7 GBrowse link increases glucuronidation ISO 14 22,499,152 22,522,842 RGD:6480464 CTD
G Ugt2b7 UDP glucuronosyltransferase 2 family, polypeptide B7 GBrowse link increases glucuronidation ISO 14 22,499,152 22,522,842 RGD:6480464 CTD
G Ugt2b7 UDP glucuronosyltransferase 2 family, polypeptide B7 GBrowse link affects metabolic processing ISO 14 22,499,152 22,522,842 RGD:6480464 CTD
sodium cholate term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 GBrowse link multiple interactions EXP 12 9,517,016 9,541,000 RGD:6480464 CTD
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 GBrowse link multiple interactions ISO 12 9,517,016 9,541,000 RGD:6480464 CTD
taurocholic acid term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Abca8 ATP-binding cassette, subfamily A (ABC1), member 8 GBrowse link affects transport ISO 10 99,392,053 99,452,833 RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 affects import ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 affects transport ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 multiple interactions ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 increases export ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 affects transport ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 affects transport ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 decreases uptake ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 affects import EXP RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 affects transport EXP RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 multiple interactions EXP RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 increases secretion EXP RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 multiple interactions EXP RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 affects secretion EXP RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 affects transport EXP RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 increases export EXP RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 increases expression EXP RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 multiple interactions EXP RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 multiple interactions EXP RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 multiple interactions EXP RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 multiple interactions ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 affects transport ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 increases export ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 increases import ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 affects transport ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 affects transport EXP RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 affects transport ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 affects transport EXP RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 increases export EXP RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 affects transport ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 affects transport EXP RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 increases export EXP RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 affects transport ISO RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 increases export EXP RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 increases export EXP RGD:6480464 CTD
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 affects transport ISO RGD:6480464 CTD
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A GBrowse link increases expression EXP 4 21,709,855 21,796,628 RGD:6480464 CTD
G Abcb4 ATP-binding cassette, subfamily B (MDR/TAP), member 4 GBrowse link increases expression EXP 4 21,946,274 22,004,328 RGD:6480464 CTD
G Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 increases activity EXP RGD:6480464 CTD
G Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 multiple interactions EXP RGD:6480464 CTD
G Abcc3 ATP-binding cassette, subfamily C (CFTR/MRP), member 3 GBrowse link increases activity ISO 10 82,986,552 83,030,799 RGD:6480464 CTD
G Abcc3 ATP-binding cassette, subfamily C (CFTR/MRP), member 3 GBrowse link affects transport EXP 10 82,986,552 83,030,799 RGD:6480464 CTD
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link multiple interactions EXP 6 137,640,482 137,657,552 RGD:6480464 CTD
G Apoa1 apolipoprotein A-I decreases expression ISO RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link multiple interactions ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link increases expression ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Blvra biliverdin reductase A GBrowse link increases expression ISO 3 114,627,972 114,645,004 RGD:6480464 CTD
G Bnip3l BCL2/adenovirus E1B interacting protein 3-like GBrowse link increases expression EXP 15 46,516,626 46,539,756 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp8 caspase 8 GBrowse link multiple interactions EXP 9 57,389,353 57,437,803 RGD:6480464 CTD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link multiple interactions EXP 5 160,704,234 160,721,796 RGD:6480464 CTD
G Cav1 caveolin 1, caveolae protein GBrowse link increases secretion ISO 4 42,956,102 42,989,057 RGD:6480464 CTD
G Cav2 caveolin 2 GBrowse link increases secretion ISO 4 42,932,127 42,939,503 RGD:6480464 CTD
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link multiple interactions ISO 10 70,256,263 70,258,061 RGD:6480464 CTD
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link increases expression ISO 10 70,256,263 70,258,061 RGD:6480464 CTD
G Ccl20 chemokine (C-C motif) ligand 20 GBrowse link multiple interactions ISO 9 82,440,965 82,443,542 RGD:6480464 CTD
G Ccl20 chemokine (C-C motif) ligand 20 GBrowse link increases expression ISO 9 82,440,965 82,443,542 RGD:6480464 CTD
G Ccl3 chemokine (C-C motif) ligand 3 GBrowse link increases expression ISO 10 71,744,559 71,746,109 RGD:6480464 CTD
G Ccl4 chemokine (C-C motif) ligand 4 GBrowse link increases expression ISO 10 71,759,643 71,761,115 RGD:6480464 CTD
G Ccl5 chemokine (C-C motif) ligand 5 GBrowse link increases expression ISO 10 71,605,791 71,610,330 RGD:6480464 CTD
G Ccl7 chemokine (C-C motif) ligand 7 GBrowse link multiple interactions ISO 10 70,267,281 70,269,131 RGD:6480464 CTD
G Ccl7 chemokine (C-C motif) ligand 7 GBrowse link increases expression ISO 10 70,267,281 70,269,131 RGD:6480464 CTD
G Ccnd1 cyclin D1 GBrowse link multiple interactions ISO 1 205,357,235 205,366,757 RGD:6480464 CTD
G Ccnd1 cyclin D1 GBrowse link increases expression ISO 1 205,357,235 205,366,757 RGD:6480464 CTD
G Ccnd1 cyclin D1 GBrowse link multiple interactions ISO 1 205,357,235 205,366,757 RGD:6480464 CTD
G Ccnd1 cyclin D1 GBrowse link increases expression ISO 1 205,357,235 205,366,757 RGD:6480464 CTD
G Ccnd1 cyclin D1 GBrowse link multiple interactions ISO 1 205,357,235 205,366,757 RGD:6480464 CTD
G Ccnd1 cyclin D1 GBrowse link increases expression ISO 1 205,357,235 205,366,757 RGD:6480464 CTD
G Ccne1 cyclin E1 GBrowse link multiple interactions ISO 1 90,568,189 90,577,426 RGD:6480464 CTD
G Ccne1 cyclin E1 GBrowse link increases expression ISO 1 90,568,189 90,577,426 RGD:6480464 CTD
G Cel carboxyl ester lipase GBrowse link multiple interactions ISO 3 7,541,127 7,549,245 RGD:6480464 CTD
G Cftr cystic fibrosis transmembrane conductance regulator GBrowse link affects uptake ISO 4 43,874,852 44,041,870 RGD:6480464 CTD
G Cftr cystic fibrosis transmembrane conductance regulator GBrowse link increases activity ISO 4 43,874,852 44,041,870 RGD:6480464 CTD
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) GBrowse link multiple interactions ISO 10 39,665,850 39,667,831 RGD:6480464 CTD
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) GBrowse link increases expression ISO 10 39,665,850 39,667,831 RGD:6480464 CTD
G Csf3 colony stimulating factor 3 (granulocyte) GBrowse link increases expression ISO 10 87,473,990 87,476,365 RGD:6480464 CTD
G Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) GBrowse link increases expression ISO 14 18,690,339 18,692,118 RGD:6480464 CTD
G Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) GBrowse link multiple interactions ISO 14 18,690,339 18,692,118 RGD:6480464 CTD
G Cxcl10 chemokine (C-X-C motif) ligand 10 GBrowse link increases expression ISO 14 17,265,986 17,268,183 RGD:6480464 CTD
G Cxcl11 chemokine (C-X-C motif) ligand 11 GBrowse link increases expression ISO 14 17,250,648 17,253,423 RGD:6480464 CTD
G Cxcl11 chemokine (C-X-C motif) ligand 11 GBrowse link increases expression ISO 14 17,250,648 17,253,423 RGD:6480464 CTD
G Cxcl13 chemokine (C-X-C motif) ligand 13 GBrowse link multiple interactions ISO 14 15,126,332 15,131,368 RGD:6480464 CTD
G Cxcl13 chemokine (C-X-C motif) ligand 13 GBrowse link increases expression ISO 14 15,126,332 15,131,368 RGD:6480464 CTD
G Cxcl16 chemokine (C-X-C motif) ligand 16 GBrowse link increases expression ISO 10 57,296,126 57,300,721 RGD:6480464 CTD
G Cxcl2 chemokine (C-X-C motif) ligand 2 GBrowse link multiple interactions ISO 14 18,677,129 18,679,175 RGD:6480464 CTD
G Cxcl2 chemokine (C-X-C motif) ligand 2 GBrowse link increases expression ISO 14 18,677,129 18,679,175 RGD:6480464 CTD
G Cxcl5 chemokine (C-X-C motif) ligand 5 GBrowse link increases expression ISO 14 18,825,357 18,826,269 RGD:6480464 CTD
G Cxcl5 chemokine (C-X-C motif) ligand 5 GBrowse link multiple interactions ISO 14 18,825,357 18,826,269 RGD:6480464 CTD
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 GBrowse link multiple interactions ISO 5 19,707,159 19,716,856 RGD:6480464 CTD
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 GBrowse link decreases expression ISO 5 19,707,159 19,716,856 RGD:6480464 CTD
G Cyp7b1 cytochrome P450, family 7, subfamily b, polypeptide 1 GBrowse link decreases activity EXP 2 103,102,679 103,271,273 RGD:6480464 CTD
G Cyp7b1 cytochrome P450, family 7, subfamily b, polypeptide 1 GBrowse link decreases expression EXP 2 103,102,679 103,271,273 RGD:6480464 CTD
G Egr1 early growth response 1 GBrowse link multiple interactions ISO 18 27,343,919 27,346,117 RGD:6480464 CTD
G Egr1 early growth response 1 GBrowse link increases expression ISO 18 27,343,919 27,346,117 RGD:6480464 CTD
G Fgf19 fibroblast growth factor 19 GBrowse link multiple interactions ISO 1 205,324,890 205,328,178 RGD:6480464 CTD
G Fgf19 fibroblast growth factor 19 GBrowse link increases expression ISO 1 205,324,890 205,328,178 RGD:6480464 CTD
G Fgfr4 fibroblast growth factor receptor 4 GBrowse link multiple interactions ISO 17 15,512,144 15,527,348 RGD:6480464 CTD
G Hgf hepatocyte growth factor GBrowse link increases uptake EXP 4 14,864,357 14,932,513 RGD:6480464 CTD
G Icam1 intercellular adhesion molecule 1 GBrowse link multiple interactions EXP 8 20,040,177 20,051,939 RGD:6480464 CTD
G Icam1 intercellular adhesion molecule 1 GBrowse link increases expression EXP 8 20,040,177 20,051,939 RGD:6480464 CTD
G Icam1 intercellular adhesion molecule 1 GBrowse link multiple interactions ISO 8 20,040,177 20,051,939 RGD:6480464 CTD
G Icam1 intercellular adhesion molecule 1 GBrowse link increases expression ISO 8 20,040,177 20,051,939 RGD:6480464 CTD
G Il10 interleukin 10 GBrowse link increases expression ISO 13 43,953,900 43,957,766 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link increases expression ISO 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link multiple interactions ISO 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link multiple interactions EXP 4 456,799 461,376 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link increases expression EXP 4 456,799 461,376 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link increases expression EXP 4 456,799 461,376 RGD:6480464 CTD
G Il6 interleukin 6 GBrowse link multiple interactions EXP 4 456,799 461,376 RGD:6480464 CTD
G Kl Klotho GBrowse link multiple interactions ISO 12 3,732,712 3,772,371 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link increases phosphorylation ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mpo myeloperoxidase GBrowse link multiple interactions EXP 10 76,085,872 76,097,012 RGD:6480464 CTD
G Mpo myeloperoxidase GBrowse link increases activity EXP 10 76,085,872 76,097,012 RGD:6480464 CTD
G Mpo myeloperoxidase GBrowse link increases expression EXP 10 76,085,872 76,097,012 RGD:6480464 CTD
G Myc myelocytomatosis oncogene GBrowse link increases expression ISO 7 98,953,142 98,958,060 RGD:6480464 CTD
G Myc myelocytomatosis oncogene GBrowse link multiple interactions ISO 7 98,953,142 98,958,060 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link multiple interactions EXP 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link increases expression EXP 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 GBrowse link increases expression ISO 5 151,524,685 151,528,000 RGD:6480464 CTD
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 GBrowse link multiple interactions ISO 7 26,189,759 26,307,061 RGD:6480464 CTD
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 GBrowse link increases expression ISO 7 26,189,759 26,307,061 RGD:6480464 CTD
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 GBrowse link multiple interactions ISO 7 26,189,759 26,307,061 RGD:6480464 CTD
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 GBrowse link increases activity ISO 7 26,189,759 26,307,061 RGD:6480464 CTD
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 GBrowse link increases expression ISO 11 64,239,918 64,276,702 RGD:6480464 CTD
G Pnlip pancreatic lipase GBrowse link increases activity EXP 1 265,107,812 265,120,969 RGD:6480464 CTD
G Pnlip pancreatic lipase GBrowse link multiple interactions EXP 1 265,107,812 265,120,969 RGD:6480464 CTD
G Pon1 paraoxonase 1 GBrowse link multiple interactions ISO 4 29,936,314 29,964,821 RGD:6480464 CTD
G Pon1 paraoxonase 1 GBrowse link decreases expression ISO 4 29,936,314 29,964,821 RGD:6480464 CTD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link increases expression ISO 13 64,427,288 64,432,978 RGD:6480464 CTD
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 GBrowse link affects transport EXP 6 104,735,839 104,749,464 RGD:6480464 CTD
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 GBrowse link increases uptake ISO 6 104,735,839 104,749,464 RGD:6480464 CTD
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 GBrowse link multiple interactions EXP 6 104,735,839 104,749,464 RGD:6480464 CTD
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 GBrowse link multiple interactions ISO 6 104,735,839 104,749,464 RGD:6480464 CTD
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 GBrowse link increases uptake EXP 6 104,735,839 104,749,464 RGD:6480464 CTD
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 GBrowse link multiple interactions ISO 6 104,735,839 104,749,464 RGD:6480464 CTD
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 GBrowse link increases transport ISO 6 104,735,839 104,749,464 RGD:6480464 CTD
G Slc10a2 solute carrier family 10 (sodium/bile acid cotransporter family), member 2 GBrowse link increases uptake EXP 16 89,939,295 89,961,444 RGD:6480464 CTD
G Slc10a2 solute carrier family 10 (sodium/bile acid cotransporter family), member 2 GBrowse link increases uptake EXP 16 89,939,295 89,961,444 RGD:6480464 CTD
G Slc10a2 solute carrier family 10 (sodium/bile acid cotransporter family), member 2 GBrowse link multiple interactions EXP 16 89,939,295 89,961,444 RGD:6480464 CTD
G Slc19a1 solute carrier family 19 (folate transporter), member 1 GBrowse link multiple interactions EXP 20 11,984,283 12,001,865 RGD:6480464 CTD
G Slc19a1 solute carrier family 19 (folate transporter), member 1 GBrowse link decreases activity EXP 20 11,984,283 12,001,865 RGD:6480464 CTD
G Slc22a6 solute carrier family 22 (organic anion transporter), member 6 GBrowse link multiple interactions ISO 1 211,294,178 211,302,398 RGD:6480464 CTD
G Slc22a8 solute carrier family 22 (organic anion transporter), member 8 GBrowse link affects transport ISO 1 211,269,366 211,287,596 RGD:6480464 CTD
G Slc23a1 solute carrier family 23 (nucleobase transporters), member 1 GBrowse link increases expression ISO 18 28,238,953 28,250,889 RGD:6480464 CTD
G Slc23a2 solute carrier family 23 (nucleobase transporters), member 2 GBrowse link increases expression ISO 3 119,796,376 119,886,011 RGD:6480464 CTD
G Slco1a1 solute carrier organic anion transporter family, member 1a1 affects uptake ISO RGD:6480464 CTD
G Slco1a1 solute carrier organic anion transporter family, member 1a1 increases uptake EXP RGD:6480464 CTD
G Slco1a1 solute carrier organic anion transporter family, member 1a1 multiple interactions EXP RGD:6480464 CTD
G Slco1a1 solute carrier organic anion transporter family, member 1a1 multiple interactions EXP RGD:6480464 CTD
G Slco1a2 solute carrier organic anion transporter family, member 1A2 GBrowse link multiple interactions EXP 4 179,790,209 179,851,288 RGD:6480464 CTD
G Slco1a2 solute carrier organic anion transporter family, member 1A2 GBrowse link increases uptake EXP 4 179,790,209 179,851,288 RGD:6480464 CTD
G Slco1a4 solute carrier organic anion transporter family, member 1a4 affects uptake ISO RGD:6480464 CTD
G Slco1a4 solute carrier organic anion transporter family, member 1a4 affects transport ISO RGD:6480464 CTD
G Slco1b3 solute carrier organic anion transporter family, member 1b3 GBrowse link multiple interactions EXP 4 179,045,586 179,118,680 RGD:6480464 CTD
G Slco1b3 solute carrier organic anion transporter family, member 1b3 GBrowse link increases uptake ISO 4 179,045,586 179,118,680 RGD:6480464 CTD
G Slco1b3 solute carrier organic anion transporter family, member 1b3 GBrowse link increases uptake EXP 4 179,045,586 179,118,680 RGD:6480464 CTD
G Stat1 signal transducer and activator of transcription 1 GBrowse link increases phosphorylation EXP 9 46,455,635 46,497,560 RGD:6480464 CTD
G Stat1 signal transducer and activator of transcription 1 GBrowse link multiple interactions EXP 9 46,455,635 46,497,560 RGD:6480464 CTD
G Stat3 signal transducer and activator of transcription 3 (acute-phase response factor) GBrowse link multiple interactions ISO 10 89,821,078 89,872,970 RGD:6480464 CTD
G Stat3 signal transducer and activator of transcription 3 (acute-phase response factor) GBrowse link increases phosphorylation ISO 10 89,821,078 89,872,970 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link increases expression EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link increases expression EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link increases expression EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link increases expression EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link increases expression EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link increases expression EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link increases expression EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link increases expression EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Vcam1 vascular cell adhesion molecule 1 GBrowse link multiple interactions ISO 2 212,277,654 212,297,376 RGD:6480464 CTD
G Vcam1 vascular cell adhesion molecule 1 GBrowse link increases expression ISO 2 212,277,654 212,297,376 RGD:6480464 CTD
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 492574
    role 482262
      biological role 480454
        biochemical role 193861
          metabolite 175191
            secondary metabolite 170532
              cholic acid 277
                (23S)-methyl-3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oic acid 0
                3-[(3-cholamidopropyl)dimethylammonio]propane-1-sulfonate 0
                6alpha,20xi-murideoxycholic acid 0
                N-(2-phosphonoethyl)cholamide 0
                cholate salt + 2
                choloyl-CoA 0
                glycochenodeoxycholic acid 7-sulfate 0
                glycocholic acid 4
                hyodeoxycholic acid 3
                murideoxycholic acid 0
                taurocholic acid 177
                taurohyocholic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 492574
    subatomic particle 491537
      composite particle 491537
        hadron 491537
          baryon 491537
            nucleon 491537
              atomic nucleus 491537
                atom 491537
                  main group element atom 461203
                    p-block element atom 458699
                      carbon group element atom 410677
                        carbon atom 407233
                          organic molecular entity 407226
                            organic molecule 359465
                              organic cyclic compound 298342
                                organic polycyclic compound 82572
                                  steroid 43073
                                    steroid fundamental parent 34308
                                      cholane 1352
                                        cholanoid 1352
                                          cholanic acids 1352
                                            cholanic acid 1352
                                              5beta-cholanic acid 1352
                                                hydroxy-5beta-cholanic acid 1350
                                                  trihydroxy-5beta-cholanic acid 277
                                                    cholic acid 277
                                                      (23S)-methyl-3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oic acid 0
                                                      3-[(3-cholamidopropyl)dimethylammonio]propane-1-sulfonate 0
                                                      6alpha,20xi-murideoxycholic acid 0
                                                      N-(2-phosphonoethyl)cholamide 0
                                                      cholate salt + 2
                                                      choloyl-CoA 0
                                                      glycochenodeoxycholic acid 7-sulfate 0
                                                      glycocholic acid 4
                                                      hyodeoxycholic acid 3
                                                      murideoxycholic acid 0
                                                      taurocholic acid 177
                                                      taurohyocholic acid 0
paths to the root

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