ONTOLOGY REPORT - ANNOTATIONS

Term:3',5'-cyclic GMP
go back to main search page
Accession:CHEBI:16356 term browser browse the term
Definition:A guanyl ribonucleotide that has formula C10H12N5O7P.
Synonyms:exact_synonym: guanosine 3',5'-(hydrogen phosphate)
 related_synonym: C10H12N5O7P;   Cyclic GMP;   Guanosine 3',5'-cyclic monophosphate;   Guanosine 3',5'-cyclic phosphate;   Guanosine cyclic monophosphate;   InChI=1S/C10H12N5O7P/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17)/t3-,5-,6-,9-/m1/s1;   InChIKey=ZOOGRGPOEVQQDX-UUOKFMHZSA-N;   Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP(O)(=O)O[C@H]2[C@H]1O;   cGMP
 alt_id: CHEBI:11675;   CHEBI:1327;   CHEBI:14377;   CHEBI:19829
 xref_casrn: 7665-99-8
 xref: ChEMBL:488479 "ChEMBL COMPOUND";   ChemIDplus:7665-99-8 "CAS Registry Number";   DrugBank:DB02315 "DrugBank";   KEGG COMPOUND:7665-99-8 "CAS Registry Number";   KEGG COMPOUND:C00942 "KEGG COMPOUND"
 xref_mesh: MESH:D006152
 cyclic_relationship: is_conjugate_acid_of CHEBI:57746

  • Rat
  • Mouse
  • Human
  • All
  • show annotations for term's descendants
  •     Sort by:
3',5'-cyclic GMP term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Abcc4 ATP-binding cassette, subfamily C (CFTR/MRP), member 4 GBrowse link increases export ISO 15 103,384,848 103,611,238 RGD:6480464 CTD
G Abcc4 ATP-binding cassette, subfamily C (CFTR/MRP), member 4 GBrowse link multiple interactions ISO 15 103,384,848 103,611,238 RGD:6480464 CTD
G Abcc4 ATP-binding cassette, subfamily C (CFTR/MRP), member 4 GBrowse link increases transport ISO 15 103,384,848 103,611,238 RGD:6480464 CTD
G Abcc4 ATP-binding cassette, subfamily C (CFTR/MRP), member 4 GBrowse link multiple interactions ISO 15 103,384,848 103,611,238 RGD:6480464 CTD
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) GBrowse link multiple interactions EXP 19 54,738,556 54,750,349 RGD:6480464 CTD
G Agtr2 angiotensin II receptor, type 2 multiple interactions EXP RGD:6480464 CTD
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link multiple interactions EXP 6 137,640,482 137,657,552 RGD:6480464 CTD
G Aldh2 aldehyde dehydrogenase 2 family (mitochondrial) GBrowse link multiple interactions ISO 12 36,081,778 36,116,445 RGD:6480464 CTD
G Bdkrb1 bradykinin receptor B1 GBrowse link multiple interactions EXP 6 129,760,129 129,762,545 RGD:6480464 CTD
G Bdkrb2 bradykinin receptor B2 GBrowse link multiple interactions EXP 6 129,744,781 129,748,851 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Edn1 endothelin 1 GBrowse link multiple interactions EXP 17 28,303,886 28,309,775 RGD:6480464 CTD
G Edn1 endothelin 1 GBrowse link increases abundance EXP 17 28,303,886 28,309,775 RGD:6480464 CTD
G Edn3 endothelin 3 GBrowse link multiple interactions EXP 3 166,491,368 166,514,051 RGD:6480464 CTD
G Edn3 endothelin 3 GBrowse link increases abundance EXP 3 166,491,368 166,514,051 RGD:6480464 CTD
G Gch1 GTP cyclohydrolase 1 GBrowse link affects abundance ISO 15 23,023,996 23,139,794 RGD:6480464 CTD
G Gnrh1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) GBrowse link multiple interactions EXP 15 47,303,309 47,307,517 RGD:6480464 CTD
G Gnrh1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) GBrowse link multiple interactions EXP 15 47,303,309 47,307,517 RGD:6480464 CTD
G Hmox2 heme oxygenase (decycling) 2 GBrowse link affects abundance ISO 10 10,914,157 10,929,448 RGD:6480464 CTD
G Il12rb2 interleukin 12 receptor, beta 2 GBrowse link increases expression ISO 4 96,929,755 96,995,733 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link multiple interactions EXP 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link increases abundance EXP 3 116,964,422 116,970,867 RGD:6480464 CTD
G Map2k1 mitogen activated protein kinase kinase 1 GBrowse link multiple interactions ISO 8 68,379,074 68,451,554 RGD:6480464 CTD
G Map2k1 mitogen activated protein kinase kinase 1 GBrowse link decreases phosphorylation ISO 8 68,379,074 68,451,554 RGD:6480464 CTD
G Map2k2 mitogen activated protein kinase kinase 2 GBrowse link decreases phosphorylation ISO 7 10,074,654 10,094,003 RGD:6480464 CTD
G Map2k2 mitogen activated protein kinase kinase 2 GBrowse link multiple interactions ISO 7 10,074,654 10,094,003 RGD:6480464 CTD
G Mapk8 mitogen-activated protein kinase 8 GBrowse link increases activity ISO 16 8,925,133 9,004,897 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link multiple interactions EXP 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nos3 nitric oxide synthase 3, endothelial cell GBrowse link multiple interactions ISO 4 6,158,847 6,179,441 RGD:6480464 CTD
G Nos3 nitric oxide synthase 3, endothelial cell GBrowse link increases abundance EXP 4 6,158,847 6,179,441 RGD:6480464 CTD
G Nppa natriuretic peptide A GBrowse link multiple interactions ISO 5 165,074,518 165,075,827 RGD:6480464 CTD
G Nppa natriuretic peptide A GBrowse link multiple interactions EXP 5 165,074,518 165,075,827 RGD:6480464 CTD
G Nppa natriuretic peptide A GBrowse link increases abundance EXP 5 165,074,518 165,075,827 RGD:6480464 CTD
G Nppa natriuretic peptide A GBrowse link multiple interactions EXP 5 165,074,518 165,075,827 RGD:6480464 CTD
G Nppa natriuretic peptide A GBrowse link increases abundance EXP 5 165,074,518 165,075,827 RGD:6480464 CTD
G Nppa natriuretic peptide A GBrowse link increases abundance EXP 5 165,074,518 165,075,827 RGD:6480464 CTD
G Nppa natriuretic peptide A GBrowse link multiple interactions EXP 5 165,074,518 165,075,827 RGD:6480464 CTD
G Nppa natriuretic peptide A GBrowse link increases abundance EXP 5 165,074,518 165,075,827 RGD:6480464 CTD
G Nppa natriuretic peptide A GBrowse link increases abundance EXP 5 165,074,518 165,075,827 RGD:6480464 CTD
G Nppa natriuretic peptide A GBrowse link increases abundance EXP 5 165,074,518 165,075,827 RGD:6480464 CTD
G Nppa natriuretic peptide A GBrowse link increases abundance EXP 5 165,074,518 165,075,827 RGD:6480464 CTD
G Nppc natriuretic peptide C GBrowse link increases chemical synthesis EXP 9 85,434,254 85,438,454 RGD:6480464 CTD
G Nppc natriuretic peptide C GBrowse link multiple interactions EXP 9 85,434,254 85,438,454 RGD:6480464 CTD
G Nppc natriuretic peptide C GBrowse link increases abundance EXP 9 85,434,254 85,438,454 RGD:6480464 CTD
G Nppc natriuretic peptide C GBrowse link multiple interactions EXP 9 85,434,254 85,438,454 RGD:6480464 CTD
G Pde10a phosphodiesterase 10A GBrowse link multiple interactions ISO 1 46,392,900 46,589,076 RGD:6480464 CTD
G Pde10a phosphodiesterase 10A GBrowse link increases hydrolysis ISO 1 46,392,900 46,589,076 RGD:6480464 CTD
G Pde11a phosphodiesterase 11A GBrowse link multiple interactions ISO 3 58,659,595 59,049,869 RGD:6480464 CTD
G Pde11a phosphodiesterase 11A GBrowse link increases hydrolysis ISO 3 58,659,595 59,049,869 RGD:6480464 CTD
G Pde1a phosphodiesterase 1A, calmodulin-dependent GBrowse link multiple interactions EXP 3 62,650,092 62,928,487 RGD:6480464 CTD
G Pde5a phosphodiesterase 5A, cGMP-specific GBrowse link decreases abundance ISO 2 219,410,394 219,550,910 RGD:6480464 CTD
G Pde9a phosphodiesterase 9A GBrowse link increases hydrolysis ISO 20 9,806,117 9,901,584 RGD:6480464 CTD
G Pde9a phosphodiesterase 9A GBrowse link multiple interactions ISO 20 9,806,117 9,901,584 RGD:6480464 CTD
G Pomc proopiomelanocortin GBrowse link affects abundance EXP 6 26,931,969 26,937,789 RGD:6480464 CTD
G Ptpn12 protein tyrosine phosphatase, non-receptor type 12 GBrowse link increases activity EXP 4 9,517,642 9,589,954 RGD:6480464 CTD
G Stk11 serine/threonine kinase 11 GBrowse link multiple interactions ISO 7 11,086,760 11,103,522 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link decreases abundance EXP 20 3,661,000 3,663,618 RGD:6480464 CTD
G Vim vimentin GBrowse link multiple interactions ISO 17 87,847,280 87,855,763 RGD:6480464 CTD
G Xdh xanthine dehydrogenase GBrowse link multiple interactions EXP 6 21,417,685 21,590,015 RGD:6480464 CTD
8-bromo-3',5'-cyclic GMP term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Edn1 endothelin 1 GBrowse link multiple interactions EXP 17 28,303,886 28,309,775 RGD:6480464 CTD
G Edn3 endothelin 3 GBrowse link multiple interactions EXP 3 166,491,368 166,514,051 RGD:6480464 CTD
G Ednrb endothelin receptor type B GBrowse link multiple interactions EXP 15 87,893,141 87,898,700 RGD:6480464 CTD
G Il1b interleukin 1 beta GBrowse link multiple interactions ISO 3 116,964,422 116,970,867 RGD:6480464 CTD
G Il4 interleukin 4 GBrowse link multiple interactions ISO 10 39,074,582 39,080,134 RGD:6480464 CTD
G Il4 interleukin 4 GBrowse link increases expression ISO 10 39,074,582 39,080,134 RGD:6480464 CTD
G Nfatc1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 GBrowse link affects localization ISO 18 77,498,654 77,581,231 RGD:6480464 CTD
G Pde5a phosphodiesterase 5A, cGMP-specific GBrowse link multiple interactions ISO 2 219,410,394 219,550,910 RGD:6480464 CTD
G Prkg1 protein kinase, cGMP-dependent, type 1 GBrowse link increases expression EXP 1 234,420,597 235,765,375 RGD:6480464 CTD
G Scnn1b sodium channel, nonvoltage-gated 1, beta GBrowse link multiple interactions ISO 1 180,682,622 180,748,068 RGD:6480464 CTD
G Sod2 superoxide dismutase 2, mitochondrial GBrowse link increases expression EXP 1 41,862,997 41,870,327 RGD:6480464 CTD
G Spp1 secreted phosphoprotein 1 multiple interactions EXP RGD:6480464 CTD
G Th tyrosine hydroxylase GBrowse link multiple interactions EXP 1 203,164,253 203,171,506 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link increases expression EXP 10 56,399,721 56,411,150 RGD:6480464 CTD
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 GBrowse link multiple interactions EXP 8 5,472,515 5,577,537 RGD:6480464 CTD
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 GBrowse link multiple interactions ISO 8 5,472,515 5,577,537 RGD:6480464 CTD
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 GBrowse link increases phosphorylation ISO 8 5,472,515 5,577,537 RGD:6480464 CTD
G Txn1 thioredoxin 1 GBrowse link multiple interactions EXP 5 75,921,365 75,933,595 RGD:6480464 CTD
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 492574
    role 482262
      biological role 480454
        biochemical role 193861
          metabolite 175191
            secondary metabolite 170532
              guanine 154
                guanyl nucleotide 126
                  guanyl ribonucleotide 126
                    3',5'-cyclic GMP 78
                      8-bromo-3',5'-cyclic GMP 20
Path 2
Term Annotations click to browse term
  CHEBI ontology 492574
    subatomic particle 491537
      composite particle 491537
        hadron 491537
          baryon 491537
            nucleon 491537
              atomic nucleus 491537
                atom 491537
                  main group element atom 461203
                    p-block element atom 458699
                      chalcogen 315660
                        oxygen atom 300604
                          oxygen molecular entity 300604
                            hydroxides 224546
                              oxoacid 143579
                                pnictogen oxoacid 8333
                                  phosphorus oxoacid 7542
                                    phosphoric acids 7407
                                      phosphoric acid 7407
                                        phosphoric acid derivative 6386
                                          phosphate 6380
                                            organic phosphate 6379
                                              carbohydrate phosphate 1779
                                                phospho sugar 1750
                                                  aldose phosphate 1733
                                                    aldopentose phosphate 1728
                                                      ribose phosphate 1726
                                                        ribonucleotide 1627
                                                          purine ribonucleotide 1581
                                                            guanyl ribonucleotide 126
                                                              3',5'-cyclic GMP 78
                                                                8-bromo-3',5'-cyclic GMP 20
paths to the root

Contact Us |  About Us |  Jobs at RGD