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Term:staurosporine
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Accession:CHEBI:15738 term browser browse the term
Definition:An indolocarbazole alkaloid that has formula C28H26N4O3.
Synonyms:exact_synonym: (5S,6R,7R,9R)-6-methoxy-5-methyl-7-methylamino-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-one
 related_synonym: C28H26N4O3;   CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13;   InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1;   InChIKey=HKSZLNNOFSGOKW-FYTWVXJKSA-N;   Staurosporin
 alt_id: CHEBI:15106;   CHEBI:45788;   CHEBI:9252
 xref_casrn: 62996-74-1
 xref: ChEMBL:473381 "ChEMBL COMPOUND";   ChemIDplus:62996-74-1 "CAS Registry Number";   DrugBank:DB02010 "DrugBank";   KEGG COMPOUND:62996-74-1 "CAS Registry Number";   KEGG COMPOUND:C02079 "KEGG COMPOUND"
 xref_mesh: MESH:D019311
 cyclic_relationship: is_conjugate_base_of CHEBI:57491

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Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 decreases activity ISO RGD:6480464 CTD
G Ache acetylcholinesterase increases activity ISO RGD:6480464 CTD
G Ache acetylcholinesterase multiple interactions ISO RGD:6480464 CTD
G Ache acetylcholinesterase increases expression ISO RGD:6480464 CTD
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link multiple interactions ISO 6 137,640,482 137,657,552 RGD:6480464 CTD
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link multiple interactions EXP 6 137,640,482 137,657,552 RGD:6480464 CTD
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link increases phosphorylation EXP 6 137,640,482 137,657,552 RGD:6480464 CTD
G App amyloid beta (A4) precursor protein GBrowse link multiple interactions ISO 11 24,457,855 24,693,851 RGD:6480464 CTD
G App amyloid beta (A4) precursor protein GBrowse link multiple interactions ISO 11 24,457,855 24,693,851 RGD:6480464 CTD
G Atg12 autophagy related 12 GBrowse link affects response to substance ISO 18 40,933,793 40,943,970 RGD:6480464 CTD
G Atg7 autophagy related 7 GBrowse link affects response to substance ISO 4 150,814,706 150,992,704 RGD:6480464 CTD
G Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 GBrowse link decreases expression EXP 12 35,266,600 35,316,237 RGD:6480464 CTD
G Bag3 Bcl2-associated athanogene 3 GBrowse link decreases response to substance ISO 1 187,781,147 187,804,835 RGD:6480464 CTD
G Bag3 Bcl2-associated athanogene 3 GBrowse link multiple interactions ISO 1 187,781,147 187,804,835 RGD:6480464 CTD
G Bag3 Bcl2-associated athanogene 3 GBrowse link decreases expression ISO 1 187,781,147 187,804,835 RGD:6480464 CTD
G Bag4 BCL2-associated athanogene 4 GBrowse link decreases expression ISO 16 70,663,821 70,680,671 RGD:6480464 CTD
G Bag6 BCL2-associated athanogene 6 GBrowse link decreases expression ISO 20 3,739,593 3,752,311 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link multiple interactions ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link multiple interactions ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link increases expression ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link multiple interactions ISO 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link affects expression EXP 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bax Bcl2-associated X protein GBrowse link affects localization EXP 1 95,933,023 95,938,176 RGD:6480464 CTD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link multiple interactions ISO 13 12,730,736 12,905,108 RGD:6480464 CTD
G Bcl2l1 Bcl2-like 1 GBrowse link affects expression EXP 3 143,129,087 143,180,199 RGD:6480464 CTD
G Bcl2l1 Bcl2-like 1 GBrowse link decreases response to substance ISO 3 143,129,087 143,180,199 RGD:6480464 CTD
G Bcl2l1 Bcl2-like 1 GBrowse link decreases response to substance ISO 3 143,129,087 143,180,199 RGD:6480464 CTD
G Bcl2l1 Bcl2-like 1 GBrowse link decreases response to substance EXP 3 143,129,087 143,180,199 RGD:6480464 CTD
G Bcl2l1 Bcl2-like 1 GBrowse link increases expression ISO 3 143,129,087 143,180,199 RGD:6480464 CTD
G Becn1 beclin 1, autophagy related GBrowse link multiple interactions ISO 10 90,317,957 90,333,329 RGD:6480464 CTD
G Becn1 beclin 1, autophagy related GBrowse link decreases response to substance ISO 10 90,317,957 90,333,329 RGD:6480464 CTD
G Bid BH3 interacting domain death agonist GBrowse link increases expression ISO 4 157,296,383 157,318,481 RGD:6480464 CTD
G Bid BH3 interacting domain death agonist GBrowse link multiple interactions ISO 4 157,296,383 157,318,481 RGD:6480464 CTD
G Birc3 baculoviral IAP repeat-containing 3 GBrowse link decreases response to substance ISO 8 4,682,202 4,696,856 RGD:6480464 CTD
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO RGD:6480464 CTD
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B GBrowse link affects expression ISO 3 105,063,018 105,116,145 RGD:6480464 CTD
G Casp1 caspase 1 GBrowse link multiple interactions ISO 8 2,027,976 2,036,872 RGD:6480464 CTD
G Casp1 caspase 1 GBrowse link affects localization ISO 8 2,027,976 2,036,872 RGD:6480464 CTD
G Casp1 caspase 1 GBrowse link increases activity ISO 8 2,027,976 2,036,872 RGD:6480464 CTD
G Casp2 caspase 2 GBrowse link increases cleavage ISO 4 70,029,728 70,047,164 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases cleavage ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases cleavage ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions EXP 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link multiple interactions ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp3 caspase 3 GBrowse link increases activity ISO 16 48,944,226 48,962,420 RGD:6480464 CTD
G Casp7 caspase 7 GBrowse link increases activity ISO 1 262,689,300 262,721,591 RGD:6480464 CTD
G Casp7 caspase 7 GBrowse link multiple interactions EXP 1 262,689,300 262,721,591 RGD:6480464 CTD
G Casp7 caspase 7 GBrowse link increases activity EXP 1 262,689,300 262,721,591 RGD:6480464 CTD
G Casp7 caspase 7 GBrowse link increases activity ISO 1 262,689,300 262,721,591 RGD:6480464 CTD
G Casp7 caspase 7 GBrowse link increases activity ISO 1 262,689,300 262,721,591 RGD:6480464 CTD
G Casp7 caspase 7 GBrowse link increases activity ISO 1 262,689,300 262,721,591 RGD:6480464 CTD
G Casp8 caspase 8 GBrowse link multiple interactions ISO 9 57,389,353 57,437,803 RGD:6480464 CTD
G Casp8 caspase 8 GBrowse link increases activity ISO 9 57,389,353 57,437,803 RGD:6480464 CTD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link multiple interactions ISO 5 160,704,234 160,721,796 RGD:6480464 CTD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link multiple interactions EXP 5 160,704,234 160,721,796 RGD:6480464 CTD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link multiple interactions ISO 5 160,704,234 160,721,796 RGD:6480464 CTD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link increases activity ISO 5 160,704,234 160,721,796 RGD:6480464 CTD
G Casp9 caspase 9, apoptosis-related cysteine peptidase GBrowse link increases activity ISO 5 160,704,234 160,721,796 RGD:6480464 CTD
G Ccr5 chemokine (C-C motif) receptor 5 GBrowse link multiple interactions EXP 8 128,907,157 128,912,272 RGD:6480464 CTD
G Cd28 Cd28 molecule GBrowse link multiple interactions ISO 9 59,342,273 59,367,743 RGD:6480464 CTD
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link multiple interactions ISO 20 7,376,325 7,386,778 RGD:6480464 CTD
G Cdkn1b cyclin-dependent kinase inhibitor 1B GBrowse link multiple interactions ISO 4 171,841,705 171,846,506 RGD:6480464 CTD
G Chrm1 cholinergic receptor, muscarinic 1 GBrowse link multiple interactions ISO 1 211,351,738 211,353,120 RGD:6480464 CTD
G Chrm1 cholinergic receptor, muscarinic 1 GBrowse link multiple interactions ISO 1 211,351,738 211,353,120 RGD:6480464 CTD
G Chrm1 cholinergic receptor, muscarinic 1 GBrowse link affects binding ISO 1 211,351,738 211,353,120 RGD:6480464 CTD
G Chrm2 cholinergic receptor, muscarinic 2 GBrowse link multiple interactions ISO 4 63,911,292 63,913,354 RGD:6480464 CTD
G Chrm3 cholinergic receptor, muscarinic 3 GBrowse link affects binding EXP 17 71,214,906 71,218,463 RGD:6480464 CTD
G Creb1 cAMP responsive element binding protein 1 GBrowse link multiple interactions ISO 9 63,170,785 63,234,727 RGD:6480464 CTD
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) GBrowse link multiple interactions ISO 10 39,665,850 39,667,831 RGD:6480464 CTD
G Csnk2a2 casein kinase 2, alpha prime polypeptide GBrowse link affects expression ISO 19 10,015,369 10,054,662 RGD:6480464 CTD
G Ctnnb1 catenin (cadherin associated protein), beta 1 GBrowse link increases phosphorylation EXP 8 125,978,161 125,987,670 RGD:6480464 CTD
G Cxcr1 chemokine (C-X-C motif) receptor 1 GBrowse link multiple interactions EXP 9 73,510,488 73,511,537 RGD:6480464 CTD
G Cxcr4 chemokine (C-X-C motif) receptor 4 GBrowse link multiple interactions EXP 13 41,308,286 41,312,190 RGD:6480464 CTD
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 GBrowse link multiple interactions ISO 8 61,462,207 61,468,237 RGD:6480464 CTD
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 GBrowse link multiple interactions ISO 8 61,462,207 61,468,237 RGD:6480464 CTD
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 GBrowse link multiple interactions ISO 8 61,462,207 61,468,237 RGD:6480464 CTD
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 GBrowse link multiple interactions EXP 8 61,462,207 61,468,237 RGD:6480464 CTD
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 GBrowse link multiple interactions EXP 8 61,462,207 61,468,237 RGD:6480464 CTD
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 GBrowse link multiple interactions EXP 1 200,918,521 200,928,919 RGD:6480464 CTD
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 GBrowse link increases expression EXP 1 200,918,521 200,928,919 RGD:6480464 CTD
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 GBrowse link multiple interactions ISO 12 9,517,016 9,541,000 RGD:6480464 CTD
G Dedd death effector domain-containing GBrowse link affects expression ISO 13 87,238,315 87,241,703 RGD:6480464 CTD
G Edn1 endothelin 1 GBrowse link decreases activity EXP 17 28,303,886 28,309,775 RGD:6480464 CTD
G Ednrb endothelin receptor type B GBrowse link multiple interactions EXP 15 87,893,141 87,898,700 RGD:6480464 CTD
G Egf epidermal growth factor GBrowse link multiple interactions ISO 2 227,103,900 227,195,062 RGD:6480464 CTD
G Egf epidermal growth factor GBrowse link multiple interactions EXP 2 227,103,900 227,195,062 RGD:6480464 CTD
G Egfr epidermal growth factor receptor GBrowse link multiple interactions ISO 14 97,617,358 97,788,211 RGD:6480464 CTD
G Epo erythropoietin GBrowse link decreases response to substance EXP 12 19,551,768 19,555,208 RGD:6480464 CTD
G Epo erythropoietin GBrowse link multiple interactions EXP 12 19,551,768 19,555,208 RGD:6480464 CTD
G Ercc5 excision repair cross-complementing rodent repair deficiency, complementation group 5 GBrowse link affects expression ISO 9 43,248,023 43,293,196 RGD:6480464 CTD
G F3 coagulation factor III (thromboplastin, tissue factor) GBrowse link multiple interactions ISO 2 218,371,050 218,382,645 RGD:6480464 CTD
G Fn1 fibronectin 1 GBrowse link multiple interactions EXP 9 70,702,181 70,771,155 RGD:6480464 CTD
G Fos FBJ osteosarcoma oncogene GBrowse link multiple interactions EXP 6 109,559,135 109,562,001 RGD:6480464 CTD
G Gclc glutamate-cysteine ligase, catalytic subunit GBrowse link multiple interactions ISO 8 82,724,429 82,762,848 RGD:6480464 CTD
G Gclm glutamate cysteine ligase, modifier subunit GBrowse link multiple interactions ISO 2 218,895,434 218,915,491 RGD:6480464 CTD
G Gfap glial fibrillary acidic protein GBrowse link multiple interactions EXP 10 92,059,881 92,068,555 RGD:6480464 CTD
G Gsta2 glutathione S-transferase alpha 2 GBrowse link multiple interactions EXP 8 83,299,249 83,312,958 RGD:6480464 CTD
G Hmox1 heme oxygenase (decycling) 1 GBrowse link multiple interactions ISO 19 13,963,139 13,969,960 RGD:6480464 CTD
G Hmox1 heme oxygenase (decycling) 1 GBrowse link multiple interactions ISO 19 13,963,139 13,969,960 RGD:6480464 CTD
G Hr hair growth associated GBrowse link multiple interactions ISO 15 50,957,053 50,972,842 RGD:6480464 CTD
G Hr hair growth associated GBrowse link affects response to substance ISO 15 50,957,053 50,972,842 RGD:6480464 CTD
G Hr hair growth associated GBrowse link multiple interactions EXP 15 50,957,053 50,972,842 RGD:6480464 CTD
G Igf1 insulin-like growth factor 1 GBrowse link multiple interactions EXP 7 24,531,669 24,605,742 RGD:6480464 CTD
G Igf1 insulin-like growth factor 1 GBrowse link affects activity EXP 7 24,531,669 24,605,742 RGD:6480464 CTD
G Il5 interleukin 5 GBrowse link decreases activity ISO 10 39,177,786 39,180,657 RGD:6480464 CTD
G Ins1 insulin 1 GBrowse link multiple interactions EXP 1 258,001,134 258,001,688 RGD:6480464 CTD
G Ins2 insulin 2 GBrowse link multiple interactions EXP 1 202,935,548 202,936,379 RGD:6480464 CTD
G Itgal integrin, alpha L GBrowse link multiple interactions ISO 1 186,561,795 186,598,908 RGD:6480464 CTD
G Itgb2 integrin, beta 2 GBrowse link multiple interactions ISO 20 11,446,521 11,485,009 RGD:6480464 CTD
G Jun jun proto-oncogene GBrowse link multiple interactions EXP 5 115,358,166 115,361,259 RGD:6480464 CTD
G Kng1 kininogen 1 GBrowse link decreases activity EXP 11 80,109,499 80,131,887 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions EXP 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions EXP 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mapt microtubule-associated protein tau GBrowse link multiple interactions ISO 10 93,411,098 93,508,762 RGD:6480464 CTD
G Mapt microtubule-associated protein tau GBrowse link multiple interactions EXP 10 93,411,098 93,508,762 RGD:6480464 CTD
G Mark1 MAP/microtubule affinity-regulating kinase 1 GBrowse link multiple interactions ISO 13 100,905,369 101,009,161 RGD:6480464 CTD
G Mcl1 myeloid cell leukemia sequence 1 increases cleavage ISO RGD:6480464 CTD
G Mcl1 myeloid cell leukemia sequence 1 decreases response to substance ISO RGD:6480464 CTD
G Mdm2 p53 E3 ubiquitin protein ligase GBrowse link multiple interactions ISO 7 56,996,694 57,020,926 RGD:6480464 CTD
G Mmp9 matrix metallopeptidase 9 GBrowse link multiple interactions ISO 3 155,985,473 155,993,433 RGD:6480464 CTD
G Mt1a metallothionein 1a GBrowse link multiple interactions ISO 19 11,261,631 11,262,647 RGD:6480464 CTD
G Myc myelocytomatosis oncogene GBrowse link multiple interactions ISO 7 98,953,142 98,958,060 RGD:6480464 CTD
G Myc myelocytomatosis oncogene GBrowse link decreases response to substance ISO 7 98,953,142 98,958,060 RGD:6480464 CTD
G Nefl neurofilament, light polypeptide GBrowse link multiple interactions EXP 15 47,636,303 47,640,176 RGD:6480464 CTD
G Nefm neurofilament, medium polypeptide GBrowse link multiple interactions EXP 15 47,698,371 47,703,350 RGD:6480464 CTD
G Ngf nerve growth factor (beta polypeptide) GBrowse link multiple interactions ISO 2 197,621,726 197,632,960 RGD:6480464 CTD
G Nos2 nitric oxide synthase 2, inducible GBrowse link multiple interactions EXP 10 65,036,884 65,072,453 RGD:6480464 CTD
G Nppa natriuretic peptide A GBrowse link multiple interactions EXP 5 165,074,518 165,075,827 RGD:6480464 CTD
G Nqo1 NAD(P)H dehydrogenase, quinone 1 GBrowse link multiple interactions EXP 19 37,251,147 37,266,040 RGD:6480464 CTD
G Ntf3 neurotrophin 3 GBrowse link multiple interactions EXP 4 162,435,781 162,506,961 RGD:6480464 CTD
G Ntf3 neurotrophin 3 GBrowse link multiple interactions EXP 4 162,435,781 162,506,961 RGD:6480464 CTD
G Nts neurotensin GBrowse link multiple interactions ISO 7 40,474,654 40,484,058 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link increases cleavage ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link increases cleavage ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link multiple interactions ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link increases cleavage ISO 13 96,309,670 96,341,486 RGD:6480464 CTD
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta GBrowse link affects localization EXP 18 35,865,837 36,318,308 RGD:6480464 CTD
G Ppp3ca protein phosphatase 3, catalytic subunit, alpha isozyme GBrowse link decreases response to substance ISO 2 234,130,176 234,409,232 RGD:6480464 CTD
G Ppp3ca protein phosphatase 3, catalytic subunit, alpha isozyme GBrowse link increases cleavage ISO 2 234,130,176 234,409,232 RGD:6480464 CTD
G Prdx1 peroxiredoxin 1 GBrowse link multiple interactions ISO 5 136,975,780 136,991,630 RGD:6480464 CTD
G Prkca protein kinase C, alpha GBrowse link multiple interactions ISO 10 97,367,196 97,638,910 RGD:6480464 CTD
G Prkca protein kinase C, alpha GBrowse link multiple interactions EXP 10 97,367,196 97,638,910 RGD:6480464 CTD
G Prkca protein kinase C, alpha GBrowse link multiple interactions EXP 10 97,367,196 97,638,910 RGD:6480464 CTD
G Prkcd protein kinase C, delta GBrowse link multiple interactions ISO 16 5,954,218 5,975,743 RGD:6480464 CTD
G Prkcd protein kinase C, delta GBrowse link multiple interactions EXP 16 5,954,218 5,975,743 RGD:6480464 CTD
G Psen2 presenilin 2 GBrowse link multiple interactions ISO 13 95,934,674 95,951,836 RGD:6480464 CTD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link multiple interactions ISO 13 64,427,288 64,432,978 RGD:6480464 CTD
G Ret ret proto-oncogene GBrowse link decreases expression EXP 4 154,448,179 154,491,103 RGD:6480464 CTD
G Slc1a1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 GBrowse link decreases activity EXP 1 232,469,746 232,549,584 RGD:6480464 CTD
G Slc30a1 solute carrier family 30 (zinc transporter), member 1 GBrowse link multiple interactions ISO 13 107,980,864 107,986,519 RGD:6480464 CTD
G Slc5a6 solute carrier family 5 (sodium-dependent vitamin transporter), member 6 GBrowse link multiple interactions ISO 6 25,301,630 25,312,901 RGD:6480464 CTD
G Snca synuclein, alpha (non A4 component of amyloid precursor) GBrowse link multiple interactions ISO 4 89,613,731 89,722,807 RGD:6480464 CTD
G Sptan1 spectrin, alpha, non-erythrocytic 1 GBrowse link multiple interactions ISO 3 8,956,380 9,021,831 RGD:6480464 CTD
G Sptan1 spectrin, alpha, non-erythrocytic 1 GBrowse link increases cleavage ISO 3 8,956,380 9,021,831 RGD:6480464 CTD
G Stat3 signal transducer and activator of transcription 3 (acute-phase response factor) GBrowse link multiple interactions ISO 10 89,821,078 89,872,970 RGD:6480464 CTD
G Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein GBrowse link multiple interactions ISO 8 93,730,131 93,820,288 RGD:6480464 CTD
G Tjp1 tight junction protein 1 GBrowse link multiple interactions EXP 1 119,684,774 119,750,532 RGD:6480464 CTD
G Tnf tumor necrosis factor GBrowse link multiple interactions ISO 20 3,661,000 3,663,618 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link multiple interactions ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link multiple interactions EXP 10 56,399,721 56,411,150 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link multiple interactions ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
G UST4r integral membrane transport protein UST4r GBrowse link multiple interactions ISO 1 210,618,706 210,688,125 RGD:6480464 CTD
G Vasp vasodilator-stimulated phosphoprotein GBrowse link multiple interactions ISO 1 78,621,494 78,636,762 RGD:6480464 CTD
G Vdac1 voltage-dependent anion channel 1 GBrowse link multiple interactions EXP 10 37,795,721 37,823,253 RGD:6480464 CTD
G Vdr vitamin D (1,25- dihydroxyvitamin D3) receptor GBrowse link increases cleavage ISO 7 136,567,614 136,617,280 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link multiple interactions ISO 9 10,520,730 10,536,071 RGD:6480464 CTD
G Vegfa vascular endothelial growth factor A GBrowse link multiple interactions ISO 9 10,520,730 10,536,071 RGD:6480464 CTD
G Vim vimentin GBrowse link multiple interactions EXP 17 87,847,280 87,855,763 RGD:6480464 CTD
G Wt1 Wilms tumor 1 GBrowse link increases expression ISO 3 90,529,704 90,577,280 RGD:6480464 CTD
midostaurin term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) GBrowse link multiple interactions EXP 19 54,738,556 54,750,349 RGD:6480464 CTD
G Egf epidermal growth factor GBrowse link multiple interactions ISO 2 227,103,900 227,195,062 RGD:6480464 CTD
G Flt3 fms-related tyrosine kinase 3 GBrowse link decreases response to substance ISO 12 8,193,629 8,268,682 RGD:6480464 CTD
G Flt3 fms-related tyrosine kinase 3 GBrowse link decreases activity ISO 12 8,193,629 8,268,682 RGD:6480464 CTD
G Jak2 Janus kinase 2 GBrowse link increases phosphorylation ISO 1 232,915,995 232,974,763 RGD:6480464 CTD
G Mapk1 mitogen activated protein kinase 1 GBrowse link multiple interactions ISO 11 85,968,732 86,030,387 RGD:6480464 CTD
G Mapk3 mitogen activated protein kinase 3 GBrowse link multiple interactions ISO 1 185,935,044 185,941,245 RGD:6480464 CTD
G Mpl myeloproliferative leukemia virus oncogene GBrowse link increases expression ISO 5 138,921,281 138,931,990 RGD:6480464 CTD
G Ptgs2 prostaglandin-endoperoxide synthase 2 GBrowse link multiple interactions EXP 13 64,427,288 64,432,978 RGD:6480464 CTD
G Tp53 tumor protein p53 GBrowse link multiple interactions ISO 10 56,399,721 56,411,150 RGD:6480464 CTD
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 492507
    role 482196
      biological role 480389
        biochemical role 193500
          enzyme inhibitor 67978
            protein kinase inhibitor 13265
              protein kinase C inhibitor 4694
                staurosporine 215
                  3'-demethylstaurosporine 0
                  linkable staurosporine analogue 0
                  midostaurin 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 492507
    subatomic particle 491470
      composite particle 491470
        hadron 491470
          baryon 491470
            nucleon 491470
              atomic nucleus 491470
                atom 491470
                  main group element atom 461139
                    p-block element atom 458635
                      carbon group element atom 410624
                        carbon atom 407181
                          organic molecular entity 407174
                            heteroorganic entity 324724
                              organonitrogen compound 150501
                                alkaloid 9599
                                  indole alkaloid 1975
                                    indolocarbazole alkaloid 215
                                      staurosporine 215
                                        3'-demethylstaurosporine 0
                                        linkable staurosporine analogue 0
                                        midostaurin 10
paths to the root

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