ONTOLOGY REPORT - ANNOTATIONS


Term:2-hydroxyestrone
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Accession:CHEBI:1156 term browser browse the term
Definition:A 2-hydroxy steroid that has formula C18H22O3.
Synonyms:exact_synonym: 2,3-dihydroxyestra-1,3,5(10)-trien-17-one
 related_synonym: C18H22O3;   InChI=1S/C18H22O3/c1-18-7-6-11-12(14(18)4-5-17(18)21)3-2-10-8-15(19)16(20)9-13(10)11/h8-9,11-12,14,19-20H,2-7H2,1H3/t11-,12+,14-,18-/m0/s1;   InChIKey=SWINWPBPEKHUOD-JPVZDGGYSA-N;   [H][C@]12CC[C@]3(C)C(=O)CC[C@@]3([H])[C@]1([H])CCc1cc(O)c(O)cc21
 xref_casrn: 362-06-1
 xref: ChEMBL:1150234 "ChEMBL COMPOUND";   ChemIDplus:362-06-1 "CAS Registry Number";   KEGG COMPOUND:362-06-1 "CAS Registry Number";   KEGG COMPOUND:C05298 "KEGG COMPOUND";   LIPID MAPS:LMST02010032 "LIPID MAPS instance"
 xref_mesh: MESH:C024980


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2-hydroxyestrone term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Ckb creatine kinase, brain GBrowse link multiple interactions EXP 6 136,452,215 136,455,122 RGD:6480464 CTD
G Esr1 estrogen receptor 1 GBrowse link affects binding ISO 1 35,523,680 35,759,891 RGD:6480464 CTD
G Esr1 estrogen receptor 1 GBrowse link multiple interactions ISO 1 35,523,680 35,759,891 RGD:6480464 CTD
G Esr2 estrogen receptor 2 (ER beta) GBrowse link multiple interactions ISO 6 98,691,167 98,775,299 RGD:6480464 CTD
G Fshb follicle stimulating hormone, beta polypeptide GBrowse link decreases expression ISO 3 92,569,344 92,571,254 RGD:6480464 CTD
G Lhb luteinizing hormone beta GBrowse link decreases expression ISO 1 95,892,999 95,893,988 RGD:6480464 CTD
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 GBrowse link increases glucuronidation ISO 9 87,091,241 87,098,362 RGD:6480464 CTD
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 GBrowse link increases glucuronidation ISO 9 87,081,132 87,098,362 RGD:6480464 CTD
G Ugt1a8 UDP glycosyltransferase 1 family, polypeptide A8 GBrowse link increases glucuronidation ISO 9 87,017,029 87,098,362 RGD:6480464 CTD
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 GBrowse link increases glucuronidation ISO 9 86,986,915 87,098,362 RGD:6480464 CTD
G Ugt2b15 UDP glucuronosyltransferase 2 family, polypeptide B15 GBrowse link increases metabolic processing ISO 14 22,346,334 22,366,860 RGD:6480464 CTD

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 492574
    role 482262
      application 245197
        pharmaceutical 174005
          drug 173802
            antineoplastic agent 67039
              estrone 204
                2-hydroxyestrone 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 492574
    subatomic particle 491537
      composite particle 491537
        hadron 491537
          baryon 491537
            nucleon 491537
              atomic nucleus 491537
                atom 491537
                  main group element atom 461203
                    p-block element atom 458699
                      carbon group element atom 410677
                        carbon atom 407233
                          organic molecular entity 407226
                            organic group 167766
                              organic divalent group 166601
                                organodiyl group 166601
                                  carbonyl group 166291
                                    carbonyl compound 166291
                                      ketone 31433
                                        oxo steroid 13480
                                          17-oxo steroid 469
                                            estrone 204
                                              2-hydroxyestrone 11
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