ONTOLOGY REPORT - ANNOTATIONS
| Term: | 2-hydroxyestrone |
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| Accession: | CHEBI:1156
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browse the term
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| Definition: | A 2-hydroxy steroid that has formula C18H22O3. |
| Synonyms: | exact_synonym: | 2,3-dihydroxyestra-1,3,5(10)-trien-17-one |
| | related_synonym: | C18H22O3; InChI=1S/C18H22O3/c1-18-7-6-11-12(14(18)4-5-17(18)21)3-2-10-8-15(19)16(20)9-13(10)11/h8-9,11-12,14,19-20H,2-7H2,1H3/t11-,12+,14-,18-/m0/s1; InChIKey=SWINWPBPEKHUOD-JPVZDGGYSA-N; [H][C@]12CC[C@]3(C)C(=O)CC[C@@]3([H])[C@]1([H])CCc1cc(O)c(O)cc21 |
| | xref_casrn: | 362-06-1 |
| | xref: | ChEMBL:1150234 "ChEMBL COMPOUND"; ChemIDplus:362-06-1 "CAS Registry Number"; KEGG COMPOUND:362-06-1 "CAS Registry Number"; KEGG COMPOUND:C05298 "KEGG COMPOUND"; LIPID MAPS:LMST02010032 "LIPID MAPS instance" |
| | xref_mesh: | MESH:C024980 |
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2-hydroxyestrone
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| G |
Ckb |
creatine kinase, brain |
|
multiple interactions |
EXP |
6 |
136,452,215 |
136,455,122 |
RGD:6480464 |
CTD |
| G |
Esr1 |
estrogen receptor 1 |
|
affects binding |
ISO |
1 |
35,523,680 |
35,759,891 |
RGD:6480464 |
CTD |
| G |
Esr1 |
estrogen receptor 1 |
|
multiple interactions |
ISO |
1 |
35,523,680 |
35,759,891 |
RGD:6480464 |
CTD |
| G |
Esr2 |
estrogen receptor 2 (ER beta) |
|
multiple interactions |
ISO |
6 |
98,691,167 |
98,775,299 |
RGD:6480464 |
CTD |
| G |
Fshb |
follicle stimulating hormone, beta polypeptide |
|
decreases expression |
ISO |
3 |
92,569,344 |
92,571,254 |
RGD:6480464 |
CTD |
| G |
Lhb |
luteinizing hormone beta |
|
decreases expression |
ISO |
1 |
95,892,999 |
95,893,988 |
RGD:6480464 |
CTD |
| G |
Ugt1a1 |
UDP glucuronosyltransferase 1 family, polypeptide A1 |
|
increases glucuronidation |
ISO |
9 |
87,091,241 |
87,098,362 |
RGD:6480464 |
CTD |
| G |
Ugt1a2 |
UDP glucuronosyltransferase 1 family, polypeptide A2 |
|
increases glucuronidation |
ISO |
9 |
87,081,132 |
87,098,362 |
RGD:6480464 |
CTD |
| G |
Ugt1a8 |
UDP glycosyltransferase 1 family, polypeptide A8 |
|
increases glucuronidation |
ISO |
9 |
87,017,029 |
87,098,362 |
RGD:6480464 |
CTD |
| G |
Ugt1a9 |
UDP glucuronosyltransferase 1 family, polypeptide A9 |
|
increases glucuronidation |
ISO |
9 |
86,986,915 |
87,098,362 |
RGD:6480464 |
CTD |
| G |
Ugt2b15 |
UDP glucuronosyltransferase 2 family, polypeptide B15 |
|
increases metabolic processing |
ISO |
14 |
22,346,334 |
22,366,860 |
RGD:6480464 |
CTD |
Term paths to the root
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