Genetic Models at MCW

If interested in obtaining any of these strains, please contact mcwcustomrats@mcw.edu .   

  

Genetic Models Available

Gene Symbol Gene No. of Models Background Strain Strain Symbol Aliases Method Availability Origination Phenotype Data Publications Ask about this Model!
Tert telomerase reverse transcriptase 1 WKY/NCrl WKY-Tertem2Mcwi CRISPR/Cas9 Live Animals (as of 2017-02-22) MCW Gene Editing Rat Resource Center
Tph2 tryptophan hydroxylase 2 2
Rag1 recombination activating 1 2
Myo1d myosin ID 1 F344/NCrl F344-Myo1dTn(sb-T2/Bart3)2.334Mcwi RRRC:00478 Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Fgl2 fibrinogen-like 2 3
Ace angiotensin I converting enzyme 2
Kcnj16 potassium voltage-gated channel subfamily J member 16 1 SS/JrHsdMcwi SS-Kcnj16em1Mcwi ZFN Live Animals; Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Nell1 neural EGFL like 1 1 F344-Nell1Tn(sb-T2/Bart3)2.195Mcwi Unknown PhysGen Publications
Spp1 secreted phosphoprotein 1 1 SHRSP/A3NCrl SHRSP-Spp1em1Mcwi CRISPR/Cas9 Cryopreserved Sperm (as of 2017-01-26) MCW Gene Editing Rat Resource Center
Bbx BBX, HMG-box containing 1 F344/NCrl F344-BbxTn(sb-T2/Bart3)2.291Mcwi RRRC:0428 Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Plcd3 phospholipase C, delta 3 2
Mas1 MAS1 proto-oncogene, G protein-coupled receptor 1 SS/JrHsdMcwi SS-Mas1em1Mcwi ZFN Live Animals; Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link Publications
Arhgef11 Rho guanine nucleotide exchange factor 11 2
Nppa natriuretic peptide A 1 SS/JrHsdMcwi SS-Nppaem4Mcwi ZFN Live Animals; Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link Publications
Rapgef4 Rap guanine nucleotide exchange factor 4 1 F344/NCrl F344-Rapgef4Tn(sb-T2/Bart3)2.314Mcwi RRRC:00479 Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Mb myoglobin 1 WKY/NCrl WKY-Mbem6Mcwi CRISPR/Cas9 Live Animals; Cryopreserved Sperm (as of 2017-02-20) MCW Gene Editing Rat Resource Center
Grm7 glutamate metabotropic receptor 7 1 SS/JrHsdMcwi SS-Grm7em2Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Csmd3 CUB and Sushi multiple domains 3 1 F344/NCrl F344-Csmd3Tn(sb-T2/Bart3)2.288Mcwi RRRC:0390 Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Abat 4-aminobutyrate aminotransferase 1 F344-AbatTn(sb-T2/Bart3)2.163Mcwi RRRC:0381 Cryopreserved Sperm (as of 2016-11-11) PhysGen Phenominer Link Publications
Cyba cytochrome b-245 alpha chain 1 SS/JrHsdMcwi SS-Cybaem1Mcwi ZFN Live Animals; Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link Publications
Kcnj11 potassium voltage-gated channel subfamily J member 11 2
Tlr4 toll-like receptor 4 1 FHH/EurMcwi FHH-Tlr4m1Mcwi RRRC:00411 Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link
Mylip myosin regulatory light chain interacting protein 2
Erbb4 erb-b2 receptor tyrosine kinase 4 1 F344/NCrl F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi RRRC:0383 Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link Publications
Ptpra protein tyrosine phosphatase, receptor type, A 1 F344/NCrl F344-PtpraTn(sb-T2/Bart3)2.261Mcwi RRRC:00370 Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Helz2 helicase with zinc finger 2 2
Myo9a myosin IXA 1 F344/NCrl F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi RRRC:00385 Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link Publications
Ghsr growth hormone secretagogue receptor 2
Enox1 ecto-NOX disulfide-thiol exchanger 1 1 F344/NCrl F344-Enox1Tn(sb-T2/Bart3)2.282Mcwi RRRC:0470 Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Pkd1 polycystin 1, transient receptor potential channel interacting 2
Msra methionine sulfoxide reductase A 2
Mmp9 matrix metallopeptidase 9 2
Adora2b adenosine A2B receptor 2
Napb NSF attachment protein beta 1 F344/NCrl F344-NapbTn(sb-T2/Bart3)2.162Mcwi F344-LOC499903Tn(sb-T2/Bart3)2.162Mcwi ;
F344-LOC499903Tn(sb-T2/Bart3)2.162Mcwi ;
RRRC:00335
Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Fmr1 fragile X mental retardation 1 2
Trafd1 TRAF type zinc finger domain containing 1 1 SS/JrHsdMcwi SS-Trafd1em1Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Fgf1 fibroblast growth factor 1 1 SS/JrHsdMcwi SS-Fgf1em2Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Spata13 spermatogenesis associated 13 1 F344/NCrl F344-Spata13Tn(sb-T2/Bart3)2.267Mcwi RRRC:00373 Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Hps6 HPS6, biogenesis of lysosomal organelles complex 2 subunit 3 1 SS-Hps6m1Mcwi Unknown PhysGen
Resp18 regulated endocrine-specific protein 18 2
Spetex-2H Spetex-2H protein 1 F344-Spetex-2HTn(sb-T2/Bart3)2.136Mcwi Unknown PhysGen Publications
Slc7a11 solute carrier family 7 member 11 1 F344/NCrl F344-Slc7a11Tn(sb-T2/Bart3)2.266Mcwi RRRC:00372 Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Lpin1 lipin 1 1 SS/JrHsdMcwi SS-Lpin1em1Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Apoe apolipoprotein E 1 SS/JrHsdMcwi SS-Apoeem9Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Cyp7b1 cytochrome P450 family 7 subfamily B member 1 1 F344/NCrl F344-Cyp7b1Tn(sb-T2/Bart3)2.306Mcwi RRRC:0472 Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Shc1 SHC adaptor protein 1 4