Genetic Models at MCW

If interested in obtaining any of these strains, please contact mcwcustomrats@mcw.edu .   

  

Genetic Models Available

Gene Symbol Gene No. of Models Background Strain Strain Symbol Aliases Method Availability Origination Phenotype Data Publications Ask about this Model!
F10 coagulation factor X 2
Cyp7b1 cytochrome P450 family 7 subfamily B member 1 1 F344/NCrl F344-Cyp7b1Tn(sb-T2/Bart3)2.306Mcwi RRRC:0472 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Nfe2l2 nuclear factor, erythroid 2-like 2 2
Syndig1 synapse differentiation inducing 1 1 F344/NCrl F344-Syndig1Tn(sb-T2/Bart3)2.171Mcwi F344-RGD1310753Tn(sb-T2/Bart3)2.171Mcwi ;
RRRC:00342
Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Rab38 RAB38, member RAS oncogene family 2
Tpcn2 two pore segment channel 2 1 SS/JrHsdMcwi SS-Tpcn2em1Mcwi ZFN Live Animals (as of 2017-01-26) MCW Gene Editing Rat Resource Center
Elmod3 ELMO domain containing 3 1 F344/NCrl F344-Elmod3Tn(sb-T2/Bart3)2.42Mcwi RRRC:0423 ;
F344-Rbed1Tn(sb-T2/Bart3)1.42Mcwi ;
F344-Rbed1Tn(sb-T2/Bart3)2.42Mcwi
Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link Publications
Pon1 paraoxonase 1 2
Stxbp5l syntaxin binding protein 5-like 1 F344/NCrl F344-Stxbp5lTn(sb-T2/Bart3)2.202Mcwi RRRC:00386 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link Publications
Kcnh7 potassium voltage-gated channel subfamily H member 7 1 F344/NCrl F344-Kcnh7Tn(sb-T2/Bart3)2.295Mcwi RRRC:0430 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Rasgrp3 RAS guanyl releasing protein 3 2
Mas1 MAS1 proto-oncogene, G protein-coupled receptor 1 SS/JrHsdMcwi SS-Mas1em1Mcwi ZFN Unknown (as of 2017-07-18) PhysGen Knockouts Phenominer Link Publications
Rag2 recombination activating 2 4
Sorcs1 sortilin-related VPS10 domain containing receptor 1 2
Tlr4 toll-like receptor 4 1 FHH/EurMcwi FHH-Tlr4m1Mcwi RRRC:00411 ENU Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link
Bcas3 BCAS3, microtubule associated cell migration factor 1 SS/JrHsdMcwi SS-Bcas3em4Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Phenominer Link Publications
Cd55 CD55 molecule, decay accelerating factor for complement 2
Immp1l inner mitochondrial membrane peptidase subunit 1 1 F344/NCrl F344-Immp1lTn(sb-T2/Bart3)2.246Mcwi RRRC: 0355 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Ldlr low density lipoprotein receptor 2
Kcnj16 potassium voltage-gated channel subfamily J member 16 1 SS/JrHsdMcwi SS-Kcnj16em1Mcwi ZFN Live Animals; Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications
Cubn cubilin 1 SS/JrHsdMcwi SS-Cubnem1Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications
Aldh2 aldehyde dehydrogenase 2 family (mitochondrial) 1 SS/JrHsdMcwi SS-Aldh2em2Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Phenominer Link Publications
Clcn6 chloride voltage-gated channel 6 1 SS/JrHsdMcwi SS-Clcn6em2Mcwi ZFN Live Animals; Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Phenominer Link Publications
Spp1 secreted phosphoprotein 1 3
Nat8 N-acetyltransferase 8 1 SS/JrHsdMcwi SS-Nat8em4Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications
Il2rg interleukin 2 receptor subunit gamma 4
Exoc4 exocyst complex component 4 1 F344/NCrl F344-Exoc4Tn(sb-T2/Bart3)2.317Mcwi RRRC:0456 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Lama2 laminin subunit alpha 2 1 F344/NCrl F344-Lama2Tn(sb-T2/Bart3)2.2013Mcwi RRRC:0432 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Cybb cytochrome b-245 beta chain 2
Slc24a3 solute carrier family 24 member 3 2
Cd226 CD226 molecule 1 F344/NCrl F344-Cd226Tn(sb-T2/Bart3)2.141Mcwi F344-Cd226_predictedTn(sb-T2/Bart3)2.141Mcwi ;
RRRC:0329 ;
F344-Cd226_predictedTn(sb-T2/Bart3)2.141Mcwi
Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Lcat lecithin cholesterol acyltransferase 4
Lep leptin 1 SS/JrHsdMcwi SS-Lepem5Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications
Fam227a family with sequence similarity 227, member A 1 F344/NCrl F344-Fam227aTn(sb-T2/Bart3)2.333Mcwi RRRC:0484 ;
F344-LOC685444Tn(sb-T2/Bart3)2.333Mcwi ;
F344-LOC685444Tn(sb-T2/Bart3)2.333Mcwi
Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Mmel1 membrane metallo-endopeptidase-like 1 1 F344/NCrl F344-Mmel1Tn(sb-T2/Bart3)2.255Mcwi RRRC:00358 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Publications
Ulk4 unc-51 like kinase 4 1 SS/JrHsdMcwi SS-Ulk4em3Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Phenominer Link Publications
Rag1 recombination activating 1 2
Asic3 acid sensing ion channel subunit 3 1 WKY/NCrl WKY-Asic3em6Mcwi CRISPR/Cas9 Cryorecovery (as of 2017-08-14) MCW Gene Editing Rat Resource Center
Lpin1 lipin 1 1 SS/JrHsdMcwi SS-Lpin1em1Mcwi ZFN Cryopreserved Sperm (as of 2017-01-26) PhysGen Knockouts Publications
Mb myoglobin 1 WKY/NCrl WKY-Mbem6Mcwi CRISPR/Cas9 Cryorecovery (as of 2017-07-18) MCW Gene Editing Rat Resource Center
Chrna5 cholinergic receptor nicotinic alpha 5 subunit 1 LEW/NCrl LEW-Chrna5em2Mcwi CRISPR/Cas9 Cryorecovery (as of 2017-07-18) MCW Gene Editing Rat Resource Center
Dcc DCC netrin 1 receptor 1 F344/NCrl F344-DccTn(sb-T2/Bart3)2.205Mcwi RRRC:0384 Sleeping Beauty Cryopreserved Sperm (as of 2017-01-26) PhysGen Phenominer Link Publications
Vnn1 vanin 1 2