|
.015 |
.056 |
.424 |
.018 |
.998 |
.003 |
.001 |
.003 |
.006 |
.022 |
.004 |
-- |
.018 |
.016 |
.033 |
1.0 |
.009 |
.001 |
.001 |
.073 |
.282 |
.005 |
.046 |
.0 |
.006 |
-- |
-- |
.284 |
.016 |
.432 |
.642 |
.037 |
.002 |
.246 |
.005 |
.003 |
.003 |
.015 |
.136 |
.042 |
.001 |
.621 |
.05 |
.003 |
.003 |
.001 |
1.0 |
.004 |
.002 |
.0 |
.001 |
.132 |
.163 |
.024 |
.012 |
.046 |
.017 |
.008 |
.007 |
.01 |
.019 |
.053 |
.098 |
.466 |
.545 |
.051 |
.035 |
.028 |
.013 |
.013 |
.002 |
.364 |
1.0 |
.929 |
.932 |
.984 |
.002 |
.464 |
1.0 |
.943 |
.002 |
.064 |
.001 |
.001 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.005 |
.005 |
.001 |
.013 |
.063 |
.138 |
.0 |
.049 |
.035 |
.046 |
.0 |
.003 |
.002 |
.018 |
.053 |
.086 |
.274 |
.272 |
.254 |
.204 |
.008 |
.027 |
.019 |
.121 |
.003 |
.07 |
.0 |
.001 |
.004 |
.001 |
.299 |
.013 |
.001 |
.0 |
.001 |
.385 |
-- |
.067 |
.013 |
.013 |
.001 |
.913 |
.001 |
.17 |
.0 |
.079 |
.0 |
.002 |
.001 |
.003 |
.045 |
.002 |
.014 |
.012 |
.871 |
.179 |
.0 |
.736 |
.973 |
.0 |
.001 |
.009 |
.029 |
.0 |
.014 |
.23 |
.019 |
.0 |
.028 |
.034 |
.004 |
.005 |
.006 |
.0 |
.005 |
.006 |
.149 |
.007 |
.003 |
.506 |
.135 |
.0 |
.352 |
.004 |
.001 |
.266 |
.12 |
.995 |
.997 |
.017 |
.001 |
.0 |
.001 |
.084 |
.023 |
.0 |
.001 |
.0 |
-- |
-- |
.164 |
.528 |
.188 |
.434 |
.006 |
.01 |
.009 |
.057 |
.344 |
.834 |
.018 |
.004 |
.0 |
.113 |
-- |
.003 |
.018 |
.001 |
.003 |
.004 |
.004 |
.0 |
.002 |
.005 |
.0 |
.047 |
.001 |
.173 |
.014 |
.001 |
.005 |
.025 |
.019 |
.101 |
.001 |
.001 |
.006 |
.02 |
.002 |
.0 |
.001 |
.0 |
.0 |
.084 |
.0 |
.015 |
.014 |
.016 |
.016 |
.0 |
.027 |
.04 |
.004 |
.009 |
.002 |
.949 |
.023 |
.001 |
.024 |
.006 |
.001 |
.001 |
.013 |
.042 |
.001 |
-- |
.155 |
.005 |
.063 |
-- |
-- |
-- |
-- |
.005 |
.001 |
.001 |
.001 |
.025 |
.003 |
.003 |
.001 |
.001 |
.963 |
.634 |
.093 |
.0 |
.008 |
.003 |
.003 |
.001 |
.0 |
.0 |
.023 |
.011 |
.014 |
.001 |
.001 |
.001 |
.0 |
.0 |
.151 |
.0 |
.004 |
.016 |
.001 |
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
Setbp1
|
|
A |
T |
4 |
A |
C |
T |
G |
T |
G |
T |
21 |
T |
T |
A |
G |
C |
T |
A |
C |
G |
G |
A |
C |
G |
A |
A |
C |
T |
G |
A |
A |
A |
A |
6 |
A |
A |
C |
T |
C |
T |
A |
C |
T |
G |
C |
C |
A |
G |
A |
G |
G |
10 |
C |
C |
G |
G |
T |
C |
A |
T |
C |
A |
G |
T |
T |
C |
2 |
T |
C |
C |
T |
C |
C |
2 |
A |
A |
C |
G |
G |
C |
T |
A |
C |
G |
T |
C |
A |
3 |
T |
3 |
C |
C |
T |
G |
T |
A |
C |
T |
T |
30 |
10 |
A |
C |
C |
2 |
G |
G |
G |
G |
A |
A |
A |
G |
G |
C |
C |
A |
G |
G |
T |
G |
C |
T |
G |
A |
G |
A |
A |
C |
T |
C |
A |
G |
A |
G |
A |
A |
G |
G |
C |
C |
G |
T |
C |
A |
T |
G |
C |
T |
C |
20 |
A |
C |
A |
A |
A |
G |
C |
T |
T |
G |
G |
C |
G |
A |
T |
G |
2 |
C |
A |
G |
G |
4 |
2 |
T |
2 |
A |
2 |
C |
2 |
A |
2 |
2 |
2 |
T |
C |
C |
C |
A |
A |
A |
C |
A |
C |
T |
A |
6 |
2 |
A |
A |
G |
A |
G |
T |
G |
T |
4 |
12 |
184 |
C |
C |
T |
G |
C |
C |
G |
21 |
T |
A |
G |
A |
G |
T |
2 |
G |
G |
T |
4 |
G |
C |
3 |
G |
G |
A |
3 |
G |
C |
T |
G |
C |
T |
A |
C |
C |
C |
A |
A |
T |
T |
G |
A |
G |
A |
G |
C |
A |
A |
A |
C |
C |
G |
T |
G |
G |
A |
T |
A |
T |
15 |
A |
A |
C |
G |
C |
A |
G |
T |
T |
G |
A |
T |
G |
T |
10 |
T |
A |
A |
4 |
3 |
C |
G |
C |
C |
A |
A |
T |
G |
28 |
A |
A |
G |
C |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
C
|
C
|
-
|
4/5
|
G
|
G
|
C
|
25
|
A
|
A
|
-
|
G
|
-
|
-
|
A
|
T
|
C
|
G
|
T
|
G/-
|
A
|
T
|
T
|
A
|
T
|
G
|
T
|
C
|
A
|
T
|
G
|
G
|
G
|
-
|
C
|
C
|
T
|
A
|
G
|
C
|
C
|
T
|
A
|
A
|
T
|
A
|
T
|
2
|
T
|
2
|
A
|
-
|
T
|
T
|
A
|
A
|
C
|
T
|
G
|
C
|
A
|
G
|
A
|
C
|
6
|
T
|
-
|
G
|
T
|
6/5
|
C
|
13
|
T
|
2/-
|
A/-
|
C
|
T
|
A
|
T
|
A
|
A
|
G
|
T
|
5
|
C
|
T
|
G
|
-
|
-
|
-
|
T
|
T
|
G
|
C
|
C
|
G
|
T
|
C
|
C
|
-
|
-
|
G
|
T
|
T
|
-
|
-
|
A
|
A
|
T
|
G
|
T
|
G
|
A
|
A
|
T
|
T
|
T
|
A
|
C
|
C
|
T
|
T
|
C
|
A
|
G
|
A
|
G
|
G
|
T
|
A
|
T
|
G
|
A
|
9
|
8
|
3
|
9
|
T
|
A
|
T
|
T
|
A
|
C
|
T
|
G
|
C
|
A
|
T
|
C
|
T
|
-
|
C
|
T
|
C
|
-
|
T
|
A
|
T
|
C
|
G
|
A
|
A
|
T
|
3
|
T
|
C
|
G/6
|
-
|
C/8
|
C
|
-
|
G/9
|
-
|
2/-
|
3
|
2/-
|
A/3
|
2/-
|
9
|
2/-
|
A/3
|
2/-
|
2/-
|
2/-
|
C
|
T
|
T
|
A
|
-
|
C
|
-
|
G
|
C
|
-
|
-
|
5
|
6/-
|
-
|
11
|
G
|
T
|
G
|
C
|
C
|
A
|
13
|
-
|
12/-
|
184/-
|
G
|
G
|
C
|
A
|
9
|
C/-
|
-
|
21/-
|
C
|
G
|
A
|
17
|
A
|
2
|
-
|
A
|
15
|
-
|
-
|
A
|
T
|
3/-
|
A
|
A
|
G
|
-
|
A
|
G
|
C
|
A
|
A
|
A
|
G
|
T
|
T
|
T
|
G
|
C
|
C
|
A
|
A
|
G
|
A
|
C
|
A
|
T
|
C
|
C
|
G
|
T
|
2
|
A
|
C
|
A
|
A
|
G
|
9
|
C
|
-
|
-
|
G
|
G
|
G
|
A
|
T
|
G
|
A
|
C
|
C
|
G/3
|
2
|
2
|
4
|
C
|
-
|
2
|
C
|
C
|
4/-
|
3/-
|
T
|
A
|
A
|
T
|
G
|
-
|
C
|
A
|
-
|
G
|
T
|
5
|
G
|
|