|
.081 |
.001 |
.396 |
-- |
-- |
.104 |
.12 |
.102 |
.001 |
.01 |
.065 |
.008 |
.143 |
.021 |
.001 |
.001 |
.002 |
.0 |
.09 |
.012 |
.084 |
.085 |
.105 |
.001 |
.006 |
.001 |
.012 |
.129 |
.17 |
.153 |
.831 |
-- |
.028 |
.003 |
.055 |
.228 |
.258 |
.002 |
.0 |
.851 |
.925 |
.01 |
.007 |
.016 |
.244 |
.0 |
.017 |
.0 |
.0 |
.001 |
.976 |
.001 |
.195 |
.133 |
.013 |
.291 |
.899 |
.002 |
.009 |
.033 |
.0 |
.003 |
-- |
-- |
-- |
-- |
-- |
.038 |
.007 |
.001 |
.002 |
.753 |
.023 |
.998 |
.005 |
.01 |
.0 |
.013 |
.001 |
.0 |
.009 |
.005 |
.001 |
.083 |
.089 |
.054 |
.026 |
.002 |
.006 |
.006 |
.011 |
.185 |
.11 |
.178 |
.188 |
.007 |
.979 |
.895 |
.001 |
.002 |
.0 |
.001 |
.001 |
.015 |
.065 |
.024 |
.016 |
.003 |
.62 |
.001 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.004 |
.111 |
.012 |
.046 |
.023 |
.104 |
.038 |
-- |
-- |
.009 |
.367 |
.077 |
.198 |
.01 |
.0 |
.6 |
.018 |
.052 |
.002 |
.007 |
.07 |
.029 |
.012 |
.044 |
.002 |
.3 |
.065 |
.017 |
.006 |
.026 |
.893 |
.004 |
.067 |
.008 |
.01 |
.0 |
1.0 |
.281 |
.673 |
.011 |
.013 |
.004 |
.001 |
.167 |
.0 |
.076 |
.001 |
.0 |
.006 |
.046 |
-- |
.011 |
.011 |
.012 |
.0 |
.2 |
.176 |
.148 |
.814 |
-- |
.023 |
.021 |
.141 |
.04 |
.003 |
.001 |
.189 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.763 |
.736 |
.258 |
.041 |
-- |
.037 |
.088 |
.141 |
.557 |
.001 |
.036 |
.005 |
.016 |
.002 |
.041 |
.0 |
.013 |
.005 |
.0 |
-- |
.017 |
.939 |
.227 |
.001 |
.0 |
.047 |
.086 |
.013 |
.016 |
-- |
.004 |
.002 |
.013 |
.992 |
.054 |
.012 |
.079 |
.0 |
.0 |
.011 |
.012 |
.001 |
.005 |
.001 |
-- |
-- |
-- |
.195 |
.001 |
.012 |
.009 |
.0 |
.034 |
.676 |
.003 |
.006 |
.002 |
.08 |
.001 |
.444 |
.007 |
.036 |
.034 |
.001 |
.001 |
.001 |
.406 |
.001 |
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
Scn8a
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
15 |
C |
2 |
A |
G |
C |
8 |
G |
T |
G |
C |
G |
G |
T |
C |
A |
4 |
T |
C |
A |
T |
17 |
T |
A |
T |
T |
A |
C |
T |
A |
15 |
A |
A |
C |
3 |
A |
A |
T |
G |
G |
A |
T |
T |
A |
C |
A |
C |
A |
C |
C |
C |
16 |
A |
C |
T |
A |
A |
C |
C |
T |
A |
G |
G |
T |
T |
2 |
2 |
T |
5 |
A |
A |
T |
G |
G |
C |
A |
A |
A |
G |
G |
T |
A |
C |
T |
A |
A |
T |
C |
A |
A |
A |
16 |
A |
24 |
22 |
T |
A |
A |
C |
A |
C |
G |
T |
C |
T |
124 |
C |
C |
A |
C |
T |
G |
C |
A |
T |
T |
T |
T |
C |
C |
T |
C |
G |
A |
4 |
A |
G |
A |
T |
T |
C |
A |
T |
T |
G |
G |
C |
T |
G |
C |
G |
G |
C |
120 |
A |
A |
C |
G |
C |
T |
T |
T |
T |
C |
G |
T |
T |
C |
G |
2 |
A |
C |
2 |
T |
G |
T |
T |
G |
C |
2 |
T |
7 |
G |
A |
T |
G |
T |
C |
C |
C |
A |
C |
G |
G |
G |
G |
G |
T |
T |
A |
G |
A |
A |
T |
C |
T |
T |
A |
C |
C |
A |
G |
C |
A |
G |
T |
G |
C |
G |
A |
T |
5 |
C |
7 |
T |
G |
G |
G |
A |
T |
T |
A |
T |
T |
2 |
T |
2 |
2 |
T |
C |
G |
4 |
2 |
A |
T |
2 |
T |
A |
G |
T |
4 |
G |
G |
C |
G |
G |
2 |
A |
A |
T |
C |
G |
C |
G |
C |
G |
A |
C |
T |
T |
A |
T |
C |
A |
G |
C |
A |
T |
T |
12 |
C |
C |
G |
A |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
-
|
T
|
-
|
G
|
G/2
|
T
|
-
|
2
|
C
|
A
|
T
|
-
|
A
|
-
|
A
|
G
|
-
|
-
|
T
|
C
|
-
|
-
|
A
|
G
|
C
|
C
|
2
|
T
|
2
|
G
|
-
|
G
|
G
|
T
|
-
|
G
|
G
|
G
|
A
|
A
|
G
|
C
|
G
|
3
|
G
|
G
|
-
|
5
|
G
|
G
|
2
|
-
|
G
|
5
|
A
|
A/2
|
-
|
2
|
T
|
C
|
G
|
A
|
7
|
G
|
2
|
-
|
-
|
A
|
-
|
G
|
G
|
4
|
A
|
A
|
T
|
G
|
G
|
G
|
A
|
A
|
9
|
-
|
T
|
3
|
5
|
G
|
C
|
3
|
G
|
C
|
3
|
-
|
G
|
24/-
|
-
|
C
|
T
|
G
|
T
|
2
|
-
|
A
|
G
|
G
|
C
|
-
|
T
|
T
|
G
|
T
|
2
|
C
|
G
|
T
|
A
|
C
|
A
|
6
|
T
|
T
|
C
|
T
|
A
|
G
|
-
|
C
|
3
|
G
|
C
|
C
|
C/13
|
2
|
5
|
C
|
A
|
A
|
A
|
2
|
A
|
A
|
A
|
A
|
G
|
-
|
T
|
G
|
T
|
A
|
A
|
C
|
A
|
C
|
C
|
T
|
2
|
G
|
A
|
A
|
A
|
-
|
4
|
T
|
-
|
130
|
T
|
C
|
C
|
A
|
7
|
-
|
C
|
7/-
|
A
|
C
|
C
|
A
|
G
|
T
|
2
|
T
|
G
|
2
|
A
|
A
|
A
|
C
|
A
|
C
|
-
|
G
|
A
|
G
|
G
|
C
|
T
|
G
|
C
|
G
|
-
|
A
|
-
|
A
|
T
|
G
|
A
|
-
|
3
|
3
|
A
|
G
|
C
|
-
|
-
|
-
|
C
|
A
|
T
|
T
|
-
|
C
|
C
|
G
|
C
|
C
|
-
|
T/-
|
-
|
-
|
G
|
T
|
A
|
4/-
|
2/-
|
3
|
A
|
-
|
49
|
T
|
A
|
C
|
-
|
A
|
T
|
T
|
A
|
4
|
-
|
G
|
-
|
A
|
C/5
|
9
|
2
|
A
|
G
|
T
|
G
|
T
|
C
|
C
|
G
|
C
|
T
|
G
|
4/3
|
T
|
-
|
C
|
C
|
-
|
T
|
T
|
T
|
3
|
|